CN105412371A - External medicine for treating soft tissue injury - Google Patents

Abstract

The invention relates to the field of the application of traditional Chinese medicine, and in particular discloses an external medicine for treating soft tissue injury. The external medicine for treating soft tissue injury is prepared from the following materials in a certain percentage by weight: wild chrysanthemum, flos hibisci, Chinese mesona herb, herba sarcandrae, radix berberidis, fimbriatestipulate begonia herb, folium hibisci mutabilis, Chinese pulsatilla root, saxifraga stolonifera, radices lithospermi, broadleaf holly leaf, gypsophila oldhamiana, rhizoma rehmanniae, decumbent bugle herb, potentilla discolor, climbing groundsel herb, herba orostachyos, basil, herba erigeromtis, eucalyptus oil, Chinese starjasmine stem, branches and leaves of piper wallichii, herba siegesbeckiae, herba clinopodii, carbonized hair, pollen pini, root or leaf of bigleaf beautyberry, asiatic toddalia root, Pink Plumepoppy Herb and spina gleditsiae. The external medicine disclosed by the invention is simple to prepare, good in absorption effect, long in efficacy duration, significant in curative effect, free from side effects, high in safety and low in production cost, and the external medicine is beneficial for timely relieving symptoms in patients.

Description

A kind of medicine for external use for the treatment of soft tissue injury

(1) technical field

The present invention relates to application in TCM field, particularly a kind of medicine for external use for the treatment of soft tissue injury.

(2) background technology

Soft tissue injury comprises weapons, traumatic injury, hits, dampens, puncture wound, scratch, athletic injury etc., and there are pain, swelling, hemorrhage or fracture, dislocation etc. in injury more, broadly also comprises some visceral injuries; Soft tissue injury refers to that soft tissue or skeletal muscle are subject to direct or indirect violence, or long-term chronic strains the large class wound syndrome caused.There is microcirculation disturbance, aseptic inflammation after tissue is wound, cause local swelling pain.With swelling, pain for main manifestations.Acute stage, local oozing of blood, edema, sharp ache.The adhesion of muscle, tendon, ischemic contracture may be there is late period, periarthritis, even cause joint stiffness.

At present, the medicine of state's internal therapy soft tissue injury is more, mainly based on Western medicine, there is the shortcomings such as medical expense is high, therapeutic effect is satisfied not, treatment time long, easy recurrence.

(3) summary of the invention

The present invention, in order to make up the deficiencies in the prior art, provides and a kind ofly prepares a kind of medicine for external use for the treatment of soft tissue injury simple, evident in efficacy.

The present invention is achieved through the following technical solutions:

Treat a medicine for external use for soft tissue injury, be made up of the raw material of following parts by weight:

Flos Chrysanthemi Indici 10-25 gram, Flos Hibisci 10-23 gram, Herba mesonae chinensis 11-25 gram, Herba Sarcandrae 12-23 gram, Radix Berberidis 15-26 gram, Rhizoma Begoniae Fimbristipulatae 12-26 gram, Folium Hibisci Mutabilis 10-26 gram, Radix Pulsatillae 10-25 gram, Herba Saxifragae 11-24 gram, Radix Arnebiae (Radix Lithospermi) 11-25 gram, Folium Ilicis 12-20 gram, Caulis et folium pavettae hongkongensis 10-23 gram, Radix Rehmanniae 11-25 gram, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 10-24 gram, Herba Potentillae Discoloris 10-26 gram, Herba Senecionis Scandentis 12-23 gram, Herba Orostachyos 12-25 gram, JIUCENGTA 10-26 gram, Herba Erigerontis 12-26 gram, peace leaf oil 10-24 gram, Caulis Trachelospermi 10-25 gram, Caulis et Folium piperis 11-26 gram, Herba Siegesbeckiae 13-26 gram, Herba Clinopodii 12-26 gram, Crinis Carbonisatus 10-23 gram, Pollen Pini 10-25 gram, Folium Callicarpae Macrophyllae 11-26 gram, Radix Toddaliae Asiaticae 11-25 gram, Herba Macleayae Cordatae 10-26 gram, Spina Gleditsiae 10-25 gram.

The weight proportion of its preferred each raw material is:

Flos Chrysanthemi Indici 10 grams, Flos Hibisci 10 grams, Herba mesonae chinensis 11 grams, Herba Sarcandrae 12 grams, Radix Berberidis 15 grams, Rhizoma Begoniae Fimbristipulatae 12 grams, Folium Hibisci Mutabilis 10 grams, the Radix Pulsatillae 10 grams, Herba Saxifragae 11 grams, Radix Arnebiae (Radix Lithospermi) 11 grams, Folium Ilicis 12 grams, Caulis et folium pavettae hongkongensis 10 grams, Radix Rehmanniae 11 grams, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 10 grams, Herba Potentillae Discoloris 10 grams, Herba Senecionis Scandentis 12 grams, Herba Orostachyos 12 grams, JIUCENGTA 10 grams, Herba Erigerontis 12 grams, peace leaf oil 10 grams, Caulis Trachelospermi 10 grams, Caulis et Folium piperis 11 grams, Herba Siegesbeckiae 13 grams, Herba Clinopodii 12 grams, Crinis Carbonisatus 10 grams, Pollen Pini 10 grams, Folium Callicarpae Macrophyllae 11 grams, Radix Toddaliae Asiaticae 11 grams, Herba Macleayae Cordatae 10 grams, Spina Gleditsiae 10 grams.

Chinese medicine of the present invention is unguentum, after being cleaned up by each raw material, makes unguentum according to a conventional method, spreads on affected part outward and uses.

Wherein, the pharmaceutical characteristic of each raw material is as follows:

Flos Chrysanthemi Indici: bitter, pungent, property is put down; Return lung, Liver Channel.Heat-clearing and toxic substances removing; Dispelling wind suppressing the hyperactive liver.Main furuncle; Carbuncle; Erysipelas; Eczema; Dermatitis; Anemopyretic cold; Laryngopharynx swelling and pain; Hypertension.

Flos Hibisci: cool in nature, sweet in the mouth, hardship.Return spleen channel, lung meridian, Liver Channel.Clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.The heat removing and blood cooling medicine of classifying under belonging to antipyretic.Cure mainly hemorrhoidal hamorrhage and rush down blood, red white dysentery, bleeding hemorrhoids, cough due to lung-heat, spitting of blood, leucorrhea, furuncle carbuncle, scald.To pathogenic escherichia coli and dysentery bacterium all without obvious effect; Can killing parasites for relieving itching, wash one's face with it, can scalp itch be treated; Animal experiment proves that its pollen has sensitization.Herba mesonae chinensis: cold in nature is sweet in the mouth, light.Gui Jingwu.Relieve summer heat quench one's thirst, heat-clearing and toxic substances removing.Belong to the heat removing and blood cooling medicine of antipyretic subordinate classification.With controlling thirsty, the wet fiery osteodynia of heatstroke; Closely have for diabetes, hypertension.Containing compositions such as flavonoid, phenols, terpenoid, tannin, aminoacid, polysaccharide, be therefrom separated and obtain oleanolic acid, Quercetin.According to another report, this product is made antihypelipidemic preparation, the live part of blood sugar lowering is water soluble part.

Herba Sarcandrae: property is put down, bitter in the mouth, pungent.GUIXIN warp, Liver Channel.Clearing away heat and cooling blood, speckle removing of invigorating blood circulation, dispelling wind and removing obstruction in the collateral.Belong to the heat removing and blood cooling medicine of antipyretic subordinate classification.With controlling heat in blood purpura, purpura, rheumatic arthralgia, traumatic injury, influenza, infantile pneumonia and lobar pneumonia etc.Containing left-handed class Myrrha element first, Isofraxidin etc., also containing volatile oil.Tool is antibacterial, antitumor, promotion union of fracture and antivirus action; Extractum and the cytophagy of total flavones to animal thereof have facilitation; To nonspecific inflammation, particularly gastric ulcer has the effect significantly promoting that gastric cells mucosa protection layer is repaired.

Radix Berberidis: cold in nature, bitter in the mouth is poisonous.Return Liver Channel, stomach warp, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.The heat clearing and dampness removing medicine of classifying under belonging to antipyretic.For damp-heat dysentery, jaundice, eczema, pharyngalgia conjunctival congestion, ceruminal impaction is suppurated, carbuncle sore tumefacting virus.There is resisting pathogenic microbes effect, leukocyte increasing, have reduce blood pressure, negative inotropic action, diastole arteria coronaria blood vessel, has antiarrhythmic effect, has preventive and therapeutic effect to experimental silicosis, have antitumor action.

Rhizoma Begoniae Fimbristipulatae: cool in nature is sweet in the mouth, light.Clearing away heat and cooling blood, relieving cough and resolving phlegm, dissipating blood stasis for subsidence of swelling.Belong to the heat removing and blood cooling medicine of antipyretic subordinate classification.With controlling heatstroke fever, cough due to lung-heat, spitting of blood, lymphoid tuberculosis, abdominal pain due to blood stasis, bruise, fracture, burn and scald.

Folium Hibisci Mutabilis: cool in nature, taste is micro-pungent.Return lung meridian, Liver Channel.Heat-clearing and toxic substances removing, cooling blood for hemostasis, reducing swelling and alleviating pain.Belong to the heat removing and blood cooling medicine of antipyretic subordinate classification.With controlling cough due to lung-heat, haematemesis metrorrhagia, carbuncle sore tumefacting virus, lymphadenitis, appendicitis etc., carbuncle joint abscess is controlled in external, empyrosis etc.Containing flavonoid glycoside, phenols, aminoacid, tannin, reducing sugar etc.Still there is report, containing Fumaric acid and rutin etc.Pharmacological evaluation shows, leaf, flower fluid extract have obvious antibacterial action.

The Radix Pulsatillae: cold in nature, bitter in the mouth.Return stomach warp, large intestine channel.Heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery.The heat removing and blood cooling medicine of classifying under belonging to antipyretic.Treatment bacillary dysentery, amebic dysentery, nose bleeding, bleeding hemorrhoids etc.Suitable amount used externally, smashes deposited, in addition, also has the effects such as anti-trichomonal, calmness, analgesia.Herb is containing protoanemonin; Root containing triterpene saponin, after hydrolysis aglycon and glucose and rhamnose.All there is obvious anti-ameba effect decoct and saponin inside and outside thereof, and toxicity is very low; Water extract-alcohol precipitation injection obviously can suppress transplanted tumor and tumor-bearing mice time-to-live in body, can also improve immunity of organisms, reduces spleen index, raises thymus index; Ethanol extract has inhibitory action in various degree to invisible spectro various bacteria and fungus, and antibiotic effective ingredient is protoanemonin and Anemonin.

Herba Saxifragae: cold in nature, mildly bitter flavor.Tool dispels the wind, heat clearing away, blood-cleaning detoxifying effect.Belong to the heat removing and blood cooling medicine of antipyretic subordinate classification.With controlling rubella, eczema, otitis media, erysipelas, cough haematemesis, lung abscess, metrorrhagia, haemorrhoids.Containing Quercitroside, Quercetin, 5-glucoside, Bergeninum, gallic acid, protocatechuic acid, succinic acid, first class Fumaric acid, Quercetin, chlorogenic acid, Folium Vaccinii vitis-idaeae powder glycosides and volatile oil.Inhibitory action is in various degree had to Bacillus proteus, Bacillus typhi, dysentery bacterium, staphylococcus aureus, bacillus pyocyaneus.

Radix Arnebiae (Radix Lithospermi): cold in nature is sweet in the mouth, salty.GUIXIN warp, Liver Channel.Removing heat from blood, invigorate blood circulation, rash of detoxifying.Belong to the heat removing and blood cooling medicine of antipyretic subordinate classification.With controlling, heat in blood poison is contained, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.Pharmacological testing also confirms, has anticancer, the effect such as antifertility and blood sugar lowering.Containing shikonin, acetylshikonin and polysaccharide composition.Think at present, shikonin and acetylshikonin are the main components of anti-inflammatory.In addition, antigonadotropic GLH, FSH) effect be the effect of alkannic acid at least partly, this component content accounts for 20% ~ 3% of Radix Arnebiae (Radix Lithospermi) dry weight.

Folium Ilicis: cold in nature, bitter in the mouth, sweet.Return Liver Channel, lung meridian, stomach warp.Wind and heat dispersing, relieving restlessness cough-relieving, to eliminate indigestion and phlegm.The heat removing and blood cooling medicine of classifying under belonging to antipyretic.With controlling calentura excessive thirst, headache due to pathogenic wind-heat, toothache, conjunctival congestion, Ting discharging ear, hygropyretic dysentery.Leaf is containing amyrin, lupeol, uvaol, cupreol and ursolic acid etc.Containing amaroid saponin, broad-leaved glucosides first and broad-leaved glucosides second in fresh leaf.Subcutaneous or the lumbar injection of Folium Ilicis decoct has the effect of antiearly pregnancy and anti-implantation to rat.Aqueous extracts can increase the coronary flow of guinea-pig heart, improves mice hypoxia-bearing capability significantly, extends the time-to-live of anoxia Mus, also has protective effect to the Acute Myocardial Ischemia in Rats that pituitrin causes; Obviously can increase the cerebral blood flow of anesthetized rabbit after the quiet note of Aqueous extracts, reduce cerebrovascular resistance and blood pressure.

Caulis et folium pavettae hongkongensis: cold nature, sweet in the mouth, pungent.Return Liver Channel.Clearing away heat and cooling blood.Belong to the heat removing and blood cooling medicine of antipyretic subordinate classification.Cure mainly yin asthenia generating intrinsic heat, asthenia hectic fever due to YIN-deficiency.Northeastward, diuretic is then used as Radix Phytolaccae in the ground such as Henan.

Radix Rehmanniae: clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis.Containing Martynoside., dihydro catalpol glycosides, aucubin, catalpol glycosides and several amino acids.Pharmacological evaluation confirms, has the effects such as blood sugar lowering, hemostasis, anti-disseminated inravascular coagulation and anti inflammatory immunity.

Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.): cold in nature, bitter in the mouth.Return lung meridian.Heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.Belong to the heat and toxic materials clearing away medicine of antipyretic subordinate classification.Treatment laryngopharynx swelling and pain, lung-heat hemoptysis, treating swelling and pain by traumatic injury.Containing ecdysterone, cyasterone, ajugasterone B and C, ajugalactone, ajugose, flavonoid glycoside, Saponin and alkaloid etc.

Herba Potentillae Discoloris: property is put down, sweet in the mouth, micro-hardship.Return Liver Channel, stomach warp, large intestine channel.Heat-clearing and toxic substances removing, dysentery relieving, hemostasis.Belong to the heat and toxic materials clearing away medicine of antipyretic subordinate classification.Containing compositions such as Fumaric acid, gallic acid, protocatechuic acid, Quercetin, naringenin, nimbecetin, isophthalic acids.For damp-heat dysentery, carbuncle sore tumefacting virus, heat in blood tells nosebleed, has blood in stool, metrorrhagia.

Herba Senecionis Scandentis: cold in nature, bitter in the mouth.Return Liver Channel, lung meridian.The detumescence of heat-clearing and toxic substances removing, removing heat from blood, liver heat removing and eyesight improving, parasite killing pain relieving.The heat and toxic materials clearing away medicine of classifying under belonging to antipyretic.With controlling anemopyretic cold, influenza, upper respiratory tract infection, acute tonsillitis, laryngopharynx swelling and pain, pneumonia, lobar pneumonia etc.Decoct have antibacterial, suppress the effects such as leptospira growth, anti-trichomonal, toxicity is little, and decoct gavages the median lethal dose(LD 50) can not measuring mice, has certain inhibitory action to people's trichomonas vaginitis.Main containing compositions such as aureine., Herba Senecionis Scandentis film alkali, lupenone, oleanane, β-sitoesterol, daucosterol, alkaloid, p-hydroxyphenylaceticacid, hyperin, linarin, egonol, Quercetin, racemization syringaresinol, emodin, chlorogenic acid, caffeic acids.Herba Orostachyos: cool in nature, sour in the mouth, hardship.Return Liver Channel, lung meridian, spleen channel.Cooling blood for hemostasis, removing toxic substances, sore.Belong to the heat and toxic materials clearing away medicine under antipyretic classification.With controlling dysentery, have blood in stool, hemorrhoidal bleeding, open sore part disunion of a specified duration.Herba Orostachyos herb is containing Quercetin, and Quercetin-3-glycoside, kaempferol, kaempferol-7-rhamnoside, kaempferol-3-glycoside-7-rhamnoside and oxalic acid, orostachys erudescens is containing oxalic acid.Toxotest: mouse peritoneal injected current extractum 50-100g crude drug/kg can be lethal, and guinea pig intraperitoneal injection 50g crude drug/kg also causes death.

JIUCENGTA: warm in nature, acrid in the mouth.Return lung meridian, spleen channel, stomach warp, large intestine channel.Dispelling wind to relieve the exterior syndrome, dispel the wind detumescence, eliminating stasis to stop pain, promoting blood circulation to restore menstrual flow.Belong to the pungent and warm medicine for relieving the exterior syndrome of diaphoretic medicine subordinate classification.With controlling headache due to invasion of exogenous pathogens, the flatulence due to improper diet stagnation of QI, gastric abscess, traumatic injury, snake bite and insect sting, eczema pruritus.There is the effects such as certain antibacterial, antiinflammatory, venom.

Herba Erigerontis: warm in nature, acrid in the mouth, micro-hardship.GUIXIN warp, Liver Channel.Promoting blood circulation, dredging meridian and relieving pain, expelling wind and cold.Belong to the pungent and warm medicine for relieving the exterior syndrome of diaphoretic medicine subordinate classification.With controlling apoplectic hemiplegia, obstruction of qi in the chest and cardialgia, rheumatic arthralgia, headache, toothache.Herb is containing pyromeconic acid, erigeroside (two title erigeroside), the intoxicated sour methyl ester glycoside of 7-kaempferol-7-O-β-D-Glucopyranose., apigenin, high mountain baicalin, cosmosiin, the apigenin-7-O-glucose intoxicated sour glycoside of sugar (Herba Erigerontis A prime), Herba Plantaginis flavonoid glycoside and the intoxicated sour glycoside (lamp-dish flower acetic) of high mountain baicalin-7-O-glucose are wherein the main mixture called after breviscapine containing the intoxicated sour glycoside of a small amount of apigenin-7-O-glucose with the former.

Peace leaf oil: acrid in the mouth, hardship, property is put down.Dispelling wind is antipyretic, damp eliminating removing toxic substances.Belong to pungent and cold medicine for relieving the exterior syndrome, leaf water decoction is external all has stronger bacteriostasis to staphylococcus aureus, streptococcus pneumoniae, bacillus pyocyaneus, escherichia coli, dysentery bacterium etc., and its antibacterial action and contained gallic acid etc. are relevant.Eucalyptus globulus Labill aldehyde has comparatively strong inhibitory activity to carcinogenecity promotor gene Eb viral activation.10 kinds of composition tool anti-inflammatory activities such as the Ea-Ej got in Eucalyptus globulus Labill, leaf water decoction soaks rabbit ear II degree and scalds face, and the adjacent injured tissue inflammation of scald can be made to alleviate, and local necrosis alleviates.Eucalyptus oil 10% ~ 20% suspension tool local anesthesia effect.In addition, an antioxidation is also had.With curing cold, influenza, enteritis, diarrhoea, skin pruritus, neuralgia, and burn can be controlled, except mosquito.

Caulis Trachelospermi: bitter in the mouth, cold nature.GUIXIN warp, Liver Channel, kidney channel.Dispelling wind and removing obstruction in the collateral, removing heat from blood are subsided a swelling.Belong to wind-damp dispelling bone and muscle strengthening medicine of classifying under medicine for rheumatism.Suitable amount used externally, grinds into powder and dresses or get fresh goods and mash deposited injury.Use dispelling the wind and dampness pathogens pyretic arthralgia, the contracture of muscle arteries and veins, soreness of waist and knee joint, sore throat, injury from falling down.Rattan is containing arctigenin, and tracheloside, nortracheloside, fringe matairesinoside, dambonitol, arctigenin, fringe matairesinol, tracheloside is first, nortrachelogenin.Stem and leaf is containing alkaloid.Herb contains β-Amyrin, β-XIANGSHU fat acid acetas, lupeol, Thin Layer scanning, lupeol unsaturated fatty acid ester, cupreol, stigmasterol and campesterol.

Caulis et Folium piperis: wind-damp dispelling, relaxing muscles and tendons network, strong waist knee joint, except arthralgia pain.For anemofrigid-damp arthralgia, bones and muscles pain.Weakness of the waist and knees, cough and asthma, cough of suffering from a deficiency of the kidney, sexual impotence.

Herba Siegesbeckiae: wind-damp dispelling, relieving rigidity of muscles and joints.Kind removing dampness heat, except pruritus due to wind pathogen, be the key medicine of damp and hot skin infection and skin rubella, noxious dampness pruritus.After processed with wine, its property transfers Gan Wen to by hardship, in the effect having liver and kidney tonifying by residence among wet of dispeling the wind, therefore can be used for the cards such as numb limbs and tense tendons, bones and muscles pain, soreness of the waist and knees.

Herba Clinopodii: cool in nature is bitter in the mouth, puckery.Return Liver Channel.Astringing to arrest bleeding.Belong to the astringent hemostatic of hemorrhage subordinate classification.Treatment metrorrhagia, hematuria, epistaxis, gingival hemorrhage, wound hemorrhage.

Crinis Carbonisatus: the effect having hemostasis, antiinflammatory, resisting pathogenic microbes.Grind into powder mix or oil adjust, endure cream coating.For spitting blood, spitting of blood, epistaxis, stranguria with blood, hematuria, has blood in stool, metrorrhagia, traumatic hemorrhage, dysuria.

Pollen Pini: sweet in the mouth, warm in nature.Return spleen channel, Liver Channel.To dispel the wind QI invigorating, removing dampness, hemostasis.Controlling head revolves dizzy, and middle void has a stomach-ache, chronic dysentery, and all skin ulcers wet rotten, wound hemorrhage.

Folium Callicarpae Macrophyllae: property is put down, acrid in the mouth, hardship.Return Liver Channel, lung meridian, stomach warp.Dissipating blood stasis stops blooding, reducing swelling and alleviating pain.Belong to the stasis-resolving hemostatic of hemorrhage subordinate classification.For epistaxis, spitting of blood, spits blood, has blood in stool, traumatic hemorrhage, tumbling and swelling.Leaf is containing sitosterol (sitosterol), luteolin (luteolin), apigenin (apigenin), luteolin-7-O-glucuronide (luteolin-7-O-glucuronide), apigenin-7-O-glucuronide (apigenin-7-O-glu-curonide), cupreol-β-D-Glucose glycoside (β-sitosterol-β-D-glucoside), ursolic acid (ursolicacid), 2α-Hydroxyursolic Acid (2 α-hydroxyursolicacid), Crataegolic acid (crategolicacid), behenic acid (doxosanoicacid), tricosanic acid (tricosanoicacid), lignoceric acid (tetracosanoicacid), tricosane acetoacetic ester (ethyltricosanoate) and 3, 7, 3 '-trimethoxy 5, 4 '-dihydroxyflavone (3, 7, 3 '-trimethoxy4 ',-5-dihydroxyflavone).Radix Toddaliae Asiaticae: warm in nature, acrid in the mouth, hardship.Return spleen channel, stomach warp.Wind-expelling pain-stopping, dissipating blood stasis stop blooding.Belong to the stasis-resolving hemostatic of hemorrhage subordinate classification., dysmenorrhea, amenorrhea, amebic dysentery hemorrhage with dispelling the wind and dampness pathogens arthralgia pain, stomachache, traumatic injury, haematemesis, epistaxis, knife injury, toothache, malaria.Suitable amount used externally, mashes or grinds into powder deposited affected part.Containing chelerythrine, dihydrochelerythrine etc.Experiment shows, this product biology total alkali has antiinflammatory action, can suppress dimethylbenzene induced mice ear swelling, suppresses the foot swelling of agar induced mice, suppresses leukoplania caused by sodium carboxymethyl cellulose; There is analgesic activity simultaneously, the number of times of glacial acetic acid induced mice writhing response can be reduced.

Herba Macleayae Cordatae: warm in nature, acrid in the mouth, hardship.Poisonous.GUIXIN warp, stomach warp, Liver Channel, subduing swelling and detoxicating, killing parasites for relieving itching.Belong to killing parasites for relieving itching medicine.For furunculosis abscess, chronic ulcer, scald, honeybee insect stings, stubborn dermatitis.

Spina Gleditsiae: warm in nature, acrid in the mouth.Return Liver Channel, stomach warp.Detumescence poison holding, evacuation of pus, parasite killing.Belong to killing parasites for relieving itching medicine.With control carbuncle from the beginning of or difficulty in discharging of pus; External treatment scabies leprosy.Swollen ulcer drug, the non-Cheng Zhechang of pus and Squama Manis are with using.Carbuncle joins the Chinese medicine of heat-clearing and toxic substances removing, promoting blood circulation and detumescence and so on from the beginning of often adding, as Flos Lonicerae, Radix Glycyrrhizae, Olibanum, Myrrha etc.; If the empty pus of body becomes the difficult person that bursts, join the Radix Astragali, Radix Angelicae Sinensis expelling pus and toxin by strengthening QI, its diabrosis short.Or alone with old hen with cooking.Woman's milk of separately managing property is stagnated, and joins Radix Bupleuri, the Radix Angelicae Dahuricae, Radix Rhapontici, Semen Vaccariae subside a swelling with lactogenesis.Inspissate juice with rice vinegar to be coated with outward and to control stubborn dermatitis.Containing compositions such as flavonoid glycoside, phenols, aminoacid.The decoct flat board method that burrows has inhibitory action to staphylococcus aureus and micrococcus catarrhalis; Water logging agent is 32.8% to the suppression ratio of S-180.

The present invention is with wind-expelling pain-stopping, dissipating blood stasis hemostasis for the rule for the treatment of, and multiple medical material combination is collaborative, and be mainly used in removing obstruction in the collateral to relieve pain, expelling wind and cold, promoting flow of QI and blood, removing heat from blood is subsided a swelling, and has significant therapeutic effect to treatment soft tissue injury.

Clinical observation:

(1) clinical data

The present inventor in 2005 so far, carries out clinical observation treatment to 453 example treatment soft tissue injury patients.

(2) Therapeutic Method

By obtained external application of ointment in affected part, every day two to three times.Calculate treatment time according to conditions of patients weight, patients with mild application about 5 ~ 7 days, severe case's application can be fully recovered for 10 ~ 15 days.

(3) curative effect determinate standard

Criterion of therapeutical effect is with reference to criterion of therapeutical effect relevant in " disease of tcm judgement criterion of therapeutical effect ".

Cure: clinical symptoms all disappears, and lab testing is normal.

Effective: clinical symptoms disappears substantially, test chamber checks that each index of correlation is close to normal level.

Effective: clinical symptom relief, test chamber checks that each index of correlation makes moderate progress, and sign is improved.

Invalid: clinical symptoms is without being clearly better or increasing the weight of.

(4) clinical effectiveness

Clinical cure 370 example (81.68%), effective 59 examples (13.02%), effective 21 examples (4.64%), invalid 3 examples (0.66%), total effective rate is 99.34%.

The present invention prepares simply, good absorbing effect, and duration of efficacy is long, evident in efficacy, has no side effect, and safety is high, and production cost is low, is conducive to sufferer and alleviates condition of illness in time.

(4) detailed description of the invention

Embodiment 1:

Get Flos Chrysanthemi Indici 10 grams, Flos Hibisci 10 grams, Herba mesonae chinensis 11 grams, Herba Sarcandrae 12 grams, Radix Berberidis 15 grams, Rhizoma Begoniae Fimbristipulatae 12 grams, Folium Hibisci Mutabilis 10 grams, the Radix Pulsatillae 10 grams, Herba Saxifragae 11 grams, Radix Arnebiae (Radix Lithospermi) 11 grams, Folium Ilicis 12 grams, Caulis et folium pavettae hongkongensis 10 grams, Radix Rehmanniae 11 grams, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 10 grams, Herba Potentillae Discoloris 10 grams, Herba Senecionis Scandentis 12 grams, Herba Orostachyos 12 grams, JIUCENGTA 10 grams, Herba Erigerontis 12 grams, peace leaf oil 10 grams, Caulis Trachelospermi 10 grams, Caulis et Folium piperis 11 grams, Herba Siegesbeckiae 13 grams, Herba Clinopodii 12 grams, Crinis Carbonisatus 10 grams, Pollen Pini 10 grams, Folium Callicarpae Macrophyllae 11 grams, Radix Toddaliae Asiaticae 11 grams, Herba Macleayae Cordatae 10 grams, Spina Gleditsiae 10 grams, above-mentioned raw materials is cleaned up, unguentum is made by conventional method.

Usage and dosage: by obtained external application of ointment in affected part, every day two to three times.

Embodiment 2:

Get Flos Chrysanthemi Indici 25 grams, Flos Hibisci 23 grams, Herba mesonae chinensis 25 grams, Herba Sarcandrae 23 grams, Radix Berberidis 26 grams, Rhizoma Begoniae Fimbristipulatae 26 grams, Folium Hibisci Mutabilis 26 grams, the Radix Pulsatillae 25 grams, Herba Saxifragae 24 grams, Radix Arnebiae (Radix Lithospermi) 25 grams, Folium Ilicis 20 grams, Caulis et folium pavettae hongkongensis 23 grams, Radix Rehmanniae 25 grams, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 24 grams, Herba Potentillae Discoloris 26 grams, Herba Senecionis Scandentis 23 grams, Herba Orostachyos 25 grams, JIUCENGTA 26 grams, Herba Erigerontis 26 grams, peace leaf oil 24 grams, Caulis Trachelospermi 25 grams, Caulis et Folium piperis 26 grams, Herba Siegesbeckiae 26 grams, Herba Clinopodii 26 grams, Crinis Carbonisatus 23 grams, Pollen Pini 25 grams, Folium Callicarpae Macrophyllae 26 grams, Radix Toddaliae Asiaticae 25 grams, Herba Macleayae Cordatae 26 grams, Spina Gleditsiae 25 grams, above-mentioned raw materials is cleaned up, unguentum is made by conventional method.

Usage and dosage: by obtained external application of ointment in affected part, every day two to three times.

Embodiment 3:

Get Flos Chrysanthemi Indici 18 grams, Flos Hibisci 20 grams, Herba mesonae chinensis 21 grams, Herba Sarcandrae 20 grams, Radix Berberidis 18 grams, Rhizoma Begoniae Fimbristipulatae 22 grams, Folium Hibisci Mutabilis 21 grams, the Radix Pulsatillae 23 grams, Herba Saxifragae 16 grams, Radix Arnebiae (Radix Lithospermi) 19 grams, Folium Ilicis 18 grams, Caulis et folium pavettae hongkongensis 19 grams, Radix Rehmanniae 21 grams, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 17 grams, Herba Potentillae Discoloris 16 grams, Herba Senecionis Scandentis 18 grams, Herba Orostachyos 19 grams, JIUCENGTA 21 grams, Herba Erigerontis 21 grams, peace leaf oil 19 grams, Caulis Trachelospermi 20 grams, Caulis et Folium piperis 20 grams, Herba Siegesbeckiae 21 grams, Herba Clinopodii 21 grams, Crinis Carbonisatus 18 grams, Pollen Pini 22 grams, Folium Callicarpae Macrophyllae 21 grams, Radix Toddaliae Asiaticae 21 grams, Herba Macleayae Cordatae 20 grams, Spina Gleditsiae 22 grams, above-mentioned raw materials is cleaned up, unguentum is made by conventional method.

Usage and dosage: by obtained external application of ointment in affected part, every day two to three times.

Claims (3)

1. treat the medicine for external use of soft tissue injury for one kind, it is characterized by, be made up of the raw material of following parts by weight: Flos Chrysanthemi Indici 10-25 gram, Flos Hibisci 10-23 gram, Herba mesonae chinensis 11-25 gram, Herba Sarcandrae 12-23 gram, Radix Berberidis 15-26 gram, Rhizoma Begoniae Fimbristipulatae 12-26 gram, Folium Hibisci Mutabilis 10-26 gram, Radix Pulsatillae 10-25 gram, Herba Saxifragae 11-24 gram, Radix Arnebiae (Radix Lithospermi) 11-25 gram, Folium Ilicis 12-20 gram, Caulis et folium pavettae hongkongensis 10-23 gram, Radix Rehmanniae 11-25 gram, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 10-24 gram, Herba Potentillae Discoloris 10-26 gram, Herba Senecionis Scandentis 12-23 gram, Herba Orostachyos 12-25 gram, JIUCENGTA 10-26 gram, Herba Erigerontis 12-26 gram, peace leaf oil 10-24 gram, Caulis Trachelospermi 10-25 gram, Caulis et Folium piperis 11-26 gram, Herba Siegesbeckiae 13-26 gram, Herba Clinopodii 12-26 gram, Crinis Carbonisatus 10-23 gram, Pollen Pini 10-25 gram, Folium Callicarpae Macrophyllae 11-26 gram, Radix Toddaliae Asiaticae 11-25 gram, Herba Macleayae Cordatae 10-26 gram, Spina Gleditsiae 10-25 gram.

2. a kind of medicine for external use for the treatment of soft tissue injury according to claim 1, it is characterized by, be made up of the raw material of following parts by weight: Flos Chrysanthemi Indici 10 grams, Flos Hibisci 10 grams, Herba mesonae chinensis 11 grams, Herba Sarcandrae 12 grams, Radix Berberidis 15 grams, Rhizoma Begoniae Fimbristipulatae 12 grams, Folium Hibisci Mutabilis 10 grams, the Radix Pulsatillae 10 grams, Herba Saxifragae 11 grams, Radix Arnebiae (Radix Lithospermi) 11 grams, Folium Ilicis 12 grams, Caulis et folium pavettae hongkongensis 10 grams, Radix Rehmanniae 11 grams, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 10 grams, Herba Potentillae Discoloris 10 grams, Herba Senecionis Scandentis 12 grams, Herba Orostachyos 12 grams, JIUCENGTA 10 grams, Herba Erigerontis 12 grams, peace leaf oil 10 grams, Caulis Trachelospermi 10 grams, Caulis et Folium piperis 11 grams, Herba Siegesbeckiae 13 grams, Herba Clinopodii 12 grams, Crinis Carbonisatus 10 grams, Pollen Pini 10 grams, Folium Callicarpae Macrophyllae 11 grams, Radix Toddaliae Asiaticae 11 grams, Herba Macleayae Cordatae 10 grams, Spina Gleditsiae 10 grams.

3. a kind of medicine for external use for the treatment of soft tissue injury according to claim 1, is characterized in that: described Chinese medicine is unguentum.