CN105770538A - Traditional Chinese medicine for treating local vascular access induration of hemodialysis patients - Google Patents
Traditional Chinese medicine for treating local vascular access induration of hemodialysis patients Download PDFInfo
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Abstract
The invention relates to the field of applications of traditional Chinese medicines and in particular discloses a traditional Chinese medicine for treating local vascular access induration of hemodialysis patients. The traditional Chinese medicine for treating local vascular access induration of hemodialysis patients is prepared from the following raw materials according to a certain weight ratio: Indian iphigenia bulb, subprostrate sophora, climbing groundsel herb, discolor cinquefoil herb, isatis root, fructus chebulae immaturus, lophatherum gracile, plumeria rubra, microcos paniculata, thin evodia leaf, alangium platanifolium, myrrh, corydalis tuber, frankincense, medicinal cyathula root, Caulis Spatholobi, China rose, false-yellowflower milkwort root or herb, trumpet-creeper, spina gleditsiae and fructus cnidii. The traditional Chinese medicine disclosed by the invention is easy to prepare, good in absorption effect, long in drug effect duration, obvious in curative effect, high in safety and low in production cost, does not have any side effect and contributes to timely alleviating symptoms of patients.
Description
(1) technical field
The present invention relates to application in TCM field, particularly to a kind of Chinese medicine treating the scleroma of hemodialysis patients vascular access local.
(2) background technology
Modern medicine thinks that the scleroma of vascular access local is that to benefit from blood vessel cavity wall impaired owing to prolonged and repeated puncture stimulation causes, and elasticity weakens, local organization fibrosis and cause hard tubercle cicatrization；Chinese medicine thinks that the scleroma of hemodialysis vascular path belongs to the traditional Chinese medical science " gathering " category；Due to prolonged and repeated puncture, channels local damage, causing channels and be obstructed, QI and blood is not smooth, and obstruction, formation of accumulating over a long period is gathered；Qi depression to blood stasis, venation is got along well, long-pending and in bulk is its main pathogenesis；Common Therapeutic Method has certain effect to treatment local is swollen, but detumescence is relatively slower, can affect hemodialysis and be normally carried out.
(3) summary of the invention
The present invention is in order to make up the deficiencies in the prior art, it is provided that a kind of Chinese medicine preparing treatment hemodialysis patients vascular access local scleroma simple, evident in efficacy.
The present invention is achieved through the following technical solutions:
A kind of Chinese medicine treating the scleroma of hemodialysis patients vascular access local, is made up of the raw material of following parts by weight:
Pseudobulbus Cremastrae Seu Pleiones 9-26 gram, Radix Sophorae Tonkinensis 10-25 gram, Herba Senecionis Scandentis 9-28 gram, Herba Potentillae Discoloris 9-26 gram, Radix Isatidis 10-25 gram, FRUCTUS TERMINALIAE IMMATURUS 10-26 gram, Herba Lophatheri 9-25 gram, Flos Plumeriae Acutifoliae 10-26 gram, Folium Microcoris paniculatae 10-21 gram, three hardship 6-25 gram of bifurcations, Radix Alangii 6-26 gram, Myrrha 10-26 gram, Rhizoma Corydalis 6-21 gram, Olibanum 6-9 gram, Radix Cyathulae 10-26 gram, Caulis Spatholobi 9-26 gram, Flos Rosae Chinensis 16-35 gram, Radix Polygalae fallacis 10-26 gram, Flos Campsis 9-25 gram, Spina Gleditsiae 6-26 gram, Fructus Cnidii 8-24 gram.
The weight proportion of its preferred each raw material is:
Pseudobulbus Cremastrae Seu Pleiones 9 grams, Radix Sophorae Tonkinensis 10 grams, Herba Senecionis Scandentis 9 grams, Herba Potentillae Discoloris 9 grams, Radix Isatidis 10 grams, FRUCTUS TERMINALIAE IMMATURUS 10 grams, Herba Lophatheri 9 grams, Flos Plumeriae Acutifoliae 10 grams, Folium Microcoris paniculatae 10 grams, bitter 6 grams of three bifurcations, Radix Alangii 6 grams, Myrrha 10 grams, Rhizoma Corydalis 6 grams, Olibanum 6 grams, Radix Cyathulae 10 grams, Caulis Spatholobi 9 grams, Flos Rosae Chinensis 16 grams, Radix Polygalae fallacis 10 grams, Flos Campsis 9 grams, Spina Gleditsiae 6 grams, Fructus Cnidii 8 grams.
Chinese medicine of the present invention is unguentum, after being cleaned up by each raw material, makes unguentum according to a conventional method, is externally applied to affected part and uses.
Wherein, the pharmaceutical characteristic of each raw material is as follows:
Pseudobulbus Cremastrae Seu Pleiones: cool in nature, sweet in the mouth, micro-pungent.ReturnLiver Channel、Spleen channel.Heat-clearing and toxic substances removing, dissipating phlegm and resolving masses.Belong to the heat and toxic materials clearing away medicine of antipyretic subordinate classification.Containing compositions such as glucomannan, Cremastra appendiculata element I, Cremastra appendiculata element II, hydroxy benzaldehydes.
Radix Sophorae Tonkinensis: cold in nature, bitter in the mouth is poisonous.ReturnLung meridian、Stomach warp.Heat-clearing and toxic substances removing, detumescence sore-throat relieving.Belong to the heat and toxic materials clearing away medicine of classification under antipyretic.With control fire-toxin pent up, laryngopharynx swelling and pain；The all heat of external treatment is swollen, insect-bite.Radix Sophorae Tonkinensis has antitumor, strengthens immunologic function, antiulcer, it is suppressed that high-level center, and the effect of excited low-level center, wherein alkaloid is its antineoplastic effective composition, and kinds of experiments tumor is had inhibitory action.Radix Sophorae FlavescentisAlkali also has In Vitro Bacteriostasis.Rabbit, mouse carbon tetrachloride acute liver damage and mice D-Gal hepatic injury all there is protective effect；Additionally, 5 kinds of arthritis animal model of large and small Mus are had antiinflammatory action by matrine, oxymatrine, sophocarpine etc..The alkaloid such as dauricine and matrine tool spasmolytic antiasthmatic effect.Additionally, matrine, oxymatrine, sophocarpine and dauricine tool antiarrhythmic effect；And have two-way immunologic function.There are Nausea and vomiting, stomachache, diarrhoea, tic, stupor etc. in heavy dose, and even respiratory failure is till death, notes being cautious use of.Modern clinic is used for treating laryngopharynx swelling and pain, hepatitis B, chronic active hepatitis, tracheitis, asthma, encephalitis b etc..Main containing alkaloid and flavones ingredient, other are still containing Phenylpropanoid Glycosides class, triterpene and sterol etc..Alkaloid has matrine.Oxymatrine, sophocarpine, N-oxysophocarpine, dauricine etc.；Flavone has sophoradin, sophoradin, pterocarpin, trifolirhizin etc..Alkaloid is 1.37%～1.88%, and matrine content is 0.039%, 0.177%, and oxymatrine concentration is 0.339%.1.336%.
Herba Senecionis Scandentis: cold in nature, bitter in the mouth.ReturnLiver Channel、Lung meridian.The detumescence of heat-clearing and toxic substances removing, removing heat from blood, liver heat removing and eyesight improving, parasite killing pain relieving.Belong to the heat and toxic materials clearing away medicine of classification under antipyretic.External: decoct washing, smash and apply or endure cream painting.With controlling anemopyretic cold, influenza, upper respiratory tract infection, acute tonsillitis, laryngopharynx swelling and pain, pneumonia, lobar pneumonia etc..Decoct has the effects such as antibacterial, suppression leptospira growth, anti-trichomonal, and toxicity is little, and decoct gavages the median lethal dose(LD 50) that can not measure mice, and people's trichomonas vaginitis is had certain inhibitory action.Main containing aureine., Herba Senecionis Scandentis film alkali, lupenone, oleanane, β-sitoesterol, daucosterol, alkaloid, p-hydroxyphenylaceticacid, hyperin, linarin, egonol, Quercetin, racemizationFlos CaryophylliFat element,Radix Et Rhizoma RheiThe compositions such as element, chlorogenic acid, caffeic acid.
Herba Potentillae Discoloris: property is put down, sweet in the mouth, micro-hardship.ReturnLiver Channel、Stomach warp、Large intestine channel.Heat-clearing and toxic substances removing, dysentery relieving, hemostasis.Belong to the heat and toxic materials clearing away medicine of antipyretic subordinate classification.For oral administration: to decoct soup, consumption 10～15g；Or infusing drugs in wine clothes.External: appropriate, pan-fried water smoking is washed or fresh goods is smash deposited.For damp-heat dysentery, carbuncle sore tumefacting virus, heat in blood tells nosebleed, has blood in stool, metrorrhagia.
Radix Isatidis: cold in nature, bitter in the mouth.ReturnHeart channel、Stomach warp.Heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving.Belong to the heat and toxic materials clearing away medicine of classification under antipyretic.With controlling influenza, epidemic encephalitis, encephalitis b, pneumonia, erysipelas, pyretic toxicity sends out speckle, coma tells nosebleed, pharyngeal swelling, mumps, skin ulcer rash etc..Containing indigo Magnolia denudata, indigo；And containing 18 seed amino acids, wherein arginic content is higher, and aminoacid is probably a principle active component in Radix Isatidis.Hepatitis B virus DNA is had moderate inhibitory action；The various pathogens such as staphylococcus aureus and leptospira all there is inhibitory action.
FRUCTUS TERMINALIAE IMMATURUS: property is put down, bitter in the mouth, micro-sweet, puckery.ReturnLung meridian、Large intestine channel.Clearing away heat and promoting production of body fluid, liyan jiedu.Belong to the heat and toxic materials clearing away medicine of antipyretic subordinate classification.With controlling chronic pharyngolaryngitis, hoarseness, dry laryngopharynx.Containing tannin 20%～40%.Wherein it is mainly composed of chebulinic acid, Chebulagic acid, and containing corilagin, terchebin, ellagic acid and gallic acid etc..Additionally, still containing shihimic acid, quinic acid, saccharide and aminoacid etc..
Herba Lophatheri: cold in nature, sweet in the mouth, light.ReturnHeart channel、Stomach warp、Small intestine meridian.Clearing heat and relieving fidgetness, diuresis.Belong to the heat clearing and fire purging medicine of antipyretic subordinate classification.With controlling calentura excessive thirst, hot urination drenches pain, aphtha of the mouth and tongue.Untreatable flu, cold and heat are had a headache, irritated uncomfortable in chest, restlessness of asrhenia type and insomnia.Containing triterpenes and steroid class material arundoin, Cylindrin, freidelin, cupreol, stigmasterol, campesterol,Herba TaraxaciSterol etc..By rabbit and cat it have been experienced that, Herba Lophatheri has refrigeration function.Diuresis is not strong, but can substantially increase the content of urine chloride.There is the effect raising blood glucose.Bacteriostatic test shows, staphylococcus aureus is had certain bacteriostasis by water decoction.
Flos Plumeriae Acutifoliae: property hardship sweet, micro-, taste is put down.ReturnLung meridian、Large intestine channel.Eliminating damp-heat, bowel relieving antidiarrheal, relieving cough and resolving phlegm.Belonging to the heat clearing and fire purging medicine of antipyretic subordinate, rabbit, Cavia porcellus, cat, mice are had local anesthesia and nonspecific spasmolysis by Aqueous extracts.Brown plumericin in leaf, stem can suppress growth of bacillus tubercle.With controlling diarrhea due to damp-heat, dysentery stomachache.Containing 27 kinds of volatile ingredients such as a-terpineol, nerolidol；Plumieric acid and glycoside.The peel of stem of Flos Plumeriae Acutifoliae is containing plumieride；Root is containing plumericin, isoplumericin etc.；Leaf is containing Kaempferol Glucoside, Quercetin Glucoside；Containing lupeol and acetas thereof in milk.
Folium Microcoris paniculatae: sweet in the mouth, light, cold nature.ReturnSpleen channel、Stomach warp.Heat clearing away disappears stagnant, dampness removing jaundice eliminating.Belong to the heat clearing and fire purging medicine in antipyretic subordinate, with controlling acute icterohepatitis, simple indigestion.Isolated guinea pig heart is had increase coronary flow effect by water extract, and can improve mice hypoxia-bearing capability, and the Acute Myocardial Ischemia in Rats caused by pituitrin has protective effect, increases the cerebral blood flow of anesthetized rabbit, reduces blood pressure and cerebral vascular resistance.With curing cold, dyspepsia, the abdominal distention of damp and hot dyspepsia, lack of appetite are had loose bowels, jaundice due to damp-heat.Containing flavones ingredient, have isorhamnetin, Rhizoma Kaempferiae flavin, Quercetin, 5,6,4 '-trihydroxy-3 '-methoxy flavone-7-0-rhamanopyranosyl glucoside, 5,6,8,4 '-kaempferol-7-0-rhamnoside etc..
Three bifurcations are bitter: cold in nature, bitter in the mouth.ReturnLiver Channel、Lung meridian、Stomach warp.Heat-clearing and toxic substances removing, promoting the circulation of QI to relieve pain, dampness removing to stop itchin.Belong to the heat clearing and dampness removing medicine of classification under antipyretic.The fresh leaf of external is mashed and is applied or decoct washing affected part.With controlling calentura hyperpyrexia, laryngopharynx swelling and pain, hot carbuncle toxin, rheumatic arthralgia, wet fire osteodynia, venom, gastric heat pain, treating swelling and pain by traumatic injury.Skin herpes simplex, skin pruritus, hemorrhoid are controlled in external.Leaf, root are containing alkaloid.Leaf, also containing volatile oil, is mainly composed of a-pinene and furfural in oil.
Radix Alangii: acrid in the mouth, hardship, warm in nature, poisonous.ReturnHeart channel、Liver Channel.Expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, eliminating stasis to stop pain.Belong to the blood-activating analgesic in drug for invigorating blood circulation and eliminating stasis subordinate.No matter root decoct or biology total alkali, be intravenous injection or lumbar injection, all have obvious Muscle relaxation, but do not affect the waking state of animal；The dosage generally causing Muscle relaxation can strengthen the Rythmic contractions characteristic of isolated rabbit intestinal tube, and in dose-effect relationship.When isolated frog heart and Cor Leporis are irrigated by low dose, contraction can be made to strengthen；Escalated dose asystole, even results in chamber transmission retardance, but can recover voluntarily, also have antibacterial action, cardiovascular system has inhibitory action, strengthen intestinal, uterine myometrium, strengthen hypnotic effect, antiearly pregnancy and anti-implantation, antiinflammatory etc., have nephrotoxicity.Containing venoterpine, racemization poison multitude's alkali, β-amyrin caproate, triacontanol, β-sitoesterol, containing anabasine in root, root bark, maximum with content in fibrous root, reach 0.73%, the monosomic alkali got is mainly dl-anabasine；Also isolate ipecine, N-methyl cephaeline, in addition with cardiac glycoside, phenols, aminoacid, organic acid, resin etc..
Myrrha: property is put down, acrid in the mouth, hardship.ReturnHeart channel、Liver Channel、Spleen channel.Dissipating blood stasis analgesic therapy, detumescence and promoting granulation.Belong to the blood-activating analgesic of classification under drug for invigorating blood circulation and eliminating stasis.For obstruction of qi in the chest and cardialgia, gastralgia, dysmenorrhea amenorrhea, postpartum stagnation, abdominal mass is suffered from abdominal pain, rheumatic arthralgia, traumatic injury, carbuncle skin infection.Similar to the material of other oleo-resins, Myrrha (generally with tincture) has some local irritant effect, can be used in mouth wass, it is also possible to excited enterokinesia when gastrointestinal is unable.Water logging agent tube dilution method, the dermatophytess such as trichophyton are had inhibitory action by 1:2.Mycete is had slight inhibitory action by contained volatile oil.Myrrha decoct 20mg/kg Femoral Artery Injection, can make anesthesia Canine femoral artery blood flow increase, and vascular resistance declines.
Rhizoma Corydalis: warm in nature, acrid in the mouth, hardship.ReturnLiver Channel、Spleen channel.Promoting blood circulation to remove blood stasis, regulating QI to relieve pain.Belong to the blood-activating analgesic of classification under drug for invigorating blood circulation and eliminating stasis.Treatment whole body each portion qi depression to blood stasis pain, dysmenorrhea, amenorrhea, lump in the abdomen, postpartum stagnation, injury from falling down, hernia are had a pain.Containing more than 20 kinds of alkaloids, as corydaline, protopine, a-allocryptopine,Rhizoma CoptidisAlkali, palmatine etc..The analgesia titer of total alkali is the 40% of morphine, in total alkali with Corydaline, Rhizoma Corydalis B prime, Rhizoma Corydalis Chou prime analgesic activity the most obvious, wherein Rhizoma Corydalis B prime is the strongest, Rhizoma Corydalis Chou prime is taken second place, Rhizoma Corydalis A prime is again, rabbit, dog, monkey etc. are all had sedative-hypnotic effect, tetrahydropalmatine have antagonism central excitation and strengthen central inhibitory action by bigger consumption；Intravenous Rhizoma Corydalis B prime can reduce Range of Cerebral Infarction, cerebral edema and calcium ion and suppress.Toxicity: total alkali LD50 is 2840 mg/kg, Rhizoma Corydalis B prime LD50 is 146 mg/kg.
Olibanum: warm in nature, acrid in the mouth, hardship.ReturnHeart channel、Spleen channel、Liver Channel.Regulating qi and activating blood, analgesic therapy, detumescence, granulation promoting.Belong to the blood-activating analgesic of classification under drug for invigorating blood circulation and eliminating stasis.Consumption 3～9 grams.With controlling stagnation of QI-blood, trusted subordinate's pain, ulcerative carbuncle toxic swelling, traumatic injury, rheumatic arthralgia, dysmenorrhea, postnatal blood stasis twinge.Clinic is additionally operable to treatment acute appendicitis.Resinous 60%～70%, natural gum 27%～35%, volatile oil 3%～8%.Resin is mainly composed of free a, B. boswellic acid, in conjunction with boswellic acid etc..Volatile oil is Olibanum analgesic effective ingredient, is mainly the acetic acid n-octyl of tool analgesic activity, accounts for the 92.46% of volatile oil total amount.Make index components with instrument-pinene, Somalia's Olibanum can be distinguished with Gum Olibanum Ethiopia and the Sudan's Olibanum.
Radix Cyathulae: property is put down, sweet in the mouth, micro-hardship.ReturnLiver Channel、Kidney channel.Eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome.Belong to the blood-activating and menstruation-regulating medicinal of drug for invigorating blood circulation and eliminating stasis subordinate classification.By treating rheumatic lumbocrural pain, foot flaccidity clonic spasm of the muscle, stranguria with blood, urine pouring, hematuria, women's amenorrhea, abdominal mass abdominal mass.Containing steroid compounds such as alkaloid, β-ecdysterones.Animal experiment shows, water decoction and fluid extract can make laboratory animal uterus strong contraction, and have antifertility action and effect of necessarily invigorating blood circulation.Ecdysterone gavage can promote that rat bile is secreted, and makes cholic acid and content of bilirubin increase, and cholesterol level reduces；And hypercholesterolemiain in rats caused by WR-1339 and increased TG can be suppressed, rabbit experimental atherosclerosis also there is is inhibitory action.
Caulis Spatholobi: warm in nature, bitter in the mouth, sweet.ReturnLiver Channel、Kidney channel.Enrich blood, invigorate blood circulation, dredging collateral, have antiinflammatory action.Belong to the blood-activating and menstruation-regulating medicinal of classification under drug for invigorating blood circulation and eliminating stasis.With controlling menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.Containing compositions such as multiple isoflavone, flavanone, chalcone derivative, coumestrol class, triterpenes and sterols.Water decoction is in vitro and have slight inhibitory action at body toad heart；Also can increase prime of life Sanguis Leporis seu oryctolagi cytosis, raise its hemoglobin；The Rythmic contractions characteristic in uterus can be strengthened.There are adjustment blood fat, atherosclerosis pathological changes effect.With 10～20 milliliters of Caulis Spatholobi syrup, every day 3 times, treat anemia good effect.Good clinical efficacy is had in order to " rising white electuary " or " Ji Jia rises plain soup " treatment leukopenia that Caulis Spatholobi is principal agent.Also the diseases such as rheumatic arthritis, lupus erythematosus, thrombocytopenia, acute diarrhea can be treated.
Flos Rosae Chinensis: warm in nature, sweet in the mouth.ReturnLiver Channel.Promoting blood flow to regulate menstruation, dispersing the stagnated live-QI to relieve the stagnation of QI.Belong to the blood-activating and menstruation-regulating medicinal of drug for invigorating blood circulation and eliminating stasis subordinate classification.The menoxenia that causes with controlling depression of liver-QI, dysmenorrhea, amenorrhea, chest and abdomen swelling and pain, traumatic injury, blood stasis are swollen and ache, swollen ulcer drug and scrofula etc..Should not decoct for a long time；Consumption is unsuitable excessive, excessive causes stomachache, and many clothes clothes for a long time can cause loose stool to suffer from diarrhoea.Anemia of pregnant woman is also when being cautious use of；Main containing volatile oil, major part is terpene alcohol compound.Have a stronger antifungic action, separated go out its antifungal effective ingredient be gallic acid.
Radix Polygalae fallacis: property is put down, sweet in the mouth, micro-hardship.ReturnLiver Channel、Kidney channel、Spleen channel.Benefiting QI and nourishing blood, invigorating spleen to remove dampness, promoting blood flow to regulate menstruation.Belong to the blood-activating and menstruation-regulating medicinal of drug for invigorating blood circulation and eliminating stasis subordinate classification.With body void, soreness of waist and knee joint, the edema of insufficiency of the spleen leading to overabundance of dampness, leukorrhagia, the menoxenia of blood deficiency and blood stasis, treating swelling and pain by traumatic injury after curing the disease.Containing the composition such as saponin, polysaccharide.10% and 30% decocting liquid is resistant to the Rabbits With Acute Myocardial Ischemia that pituitrin causes, and reduces guinea pig isolated heart coronary resistance, increases coronary flow；Rat kidney-type hypertension is had hypotensive effect, and its ventricular hypertrophy is had protective effect.Polysaccharide composition can improve the immunity of normal mouse, and has anti-stress effect.Additionally, to the external tool inhibitory action of hepatitis B virus.Clinically with controlling hyperlipemia, has certain curative effect.Useful on modern clinic control the diseases such as uterine prolapse, acute hepatitis, chronic hepatitis.
Flos Campsis: cold in nature, sweet in the mouth, acid.ReturnLiver Channel、Pericardium channel.Circulation of qi promoting blood stasis dispelling, cooling blood, expelling wind.Belong to the blood-activating and menstruation-regulating medicinal of drug for invigorating blood circulation and eliminating stasis subordinate classification.With controlling blood stasis amenorrhea, abdominal mass, traumatic injury, hemostagnant metrorrhagia, difficult labour, epilepsy disease, urticaria, exudative dermatitis etc..Containing flavonoid, organic acid, actinidine, Herba Boschniakiae Rossicae alkali etc..Shigella flexneri and Bacillus typhi there is inhibitory action.
Spina Gleditsiae: warm in nature, acrid in the mouth.ReturnLiver Channel、Stomach warp.Detumescence poison holding, evacuation of pus, parasite killing.Belong to killing parasites for relieving itching medicine.Being decocted in water for oral dose, suitable amount used externally, steaming with vinegar extracting juice is coated with affected part.With control carbuncle from the beginning of or difficulty in discharging of pus；External treatment scabies leprosy.Swollen ulcer drug, the non-Cheng Zhechang of pus withSquama ManisWith using.Containing compositions such as flavonoid glycoside, phenols, aminoacid.Staphylococcus aureus and micrococcus catarrhalis are had inhibitory action by the decoct flat board method that burrows；The suppression ratio of S-180 is 32.8% by water logging agent.
Fructus Cnidii: warm in nature, acrid in the mouth, hardship.ReturnKidney channel.Warming the kidney to invigorate YANG, dampness, dispel the wind, parasite killing.Belong to killing parasites for relieving itching medicine.It is decocted in water for oral dose or enters ball and dissipate.External: pan-fried water smoking is washed, or grind into powder and spread, dress.With controlling sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago, external treatment vulval eczema, married woman's pudendal pruritus, trichomonal vaginitis.Tool gonadal hormone sample, relieving asthma, the effect such as calm, local anesthesia and antimicrobial.Containing volatile oil, it is mainly composed of that pinane is rare, isovaleric acid borneol acetate, osthole, Columbianetin (+)-Columbianetin., bergapton, osthole, isopimpinellin etc..
The present invention is with promoting blood circulation to remove blood stasis, and regulating QI to relieve pain is the rule for the treatment of, and the combination of multiple medical material is collaborative, is mainly used in powder detoxifcation, resolving heat and reducing pathogenic fire, inducing diuresis to remove edema, restrain anticorrosion, dredging collateral eases pain, alleviating distention in middle-JIAO is regulated the flow of vital energy, and regulates internal organs negative and positive, promoting flow of QI and blood, the scleroma of hemodialysis patients vascular access local is had significant therapeutic effect.
Clinical observation:
(1) clinical data
453 example hemodialysis patients vascular access local scleroma patients in 2010 so far, are carried out clinical observation treatment by the present inventor.
(2) Therapeutic Method
By prepared external application of ointment in affected part, every day two to three times.Calculating treatment time, patients with mild application about 5～7 days according to conditions of patients weight, severe case even applies and can fully recover for 10～15 days.
(3) curative effect determinate standard
Criterion of therapeutical effect is with reference to criterion of therapeutical effect relevant in " disease of tcm judgement criterion of therapeutical effect ".
Cure: clinical symptoms all disappears, and lab testing is normal.
Effective: clinical symptoms disappears substantially, test chamber checks that each index of correlation is close to normal level.
Effective: clinical symptom relief, test chamber checks that each index of correlation makes moderate progress, and sign has improvement.
Invalid: clinical symptoms is without being clearly better or increasing the weight of.
(4) clinical effectiveness
Clinical cure 370 example (81.68%), effective 59 examples (13.02%), effective 21 examples (4.64%), invalid 3 examples (0.66%), total effective rate is 99.34%.
The present invention prepares simply, good absorbing effect, and duration of efficacy is long, evident in efficacy, has no side effect, and safety is high, and production cost is low, is conducive to sufferer to alleviate condition of illness in time.
(4) detailed description of the invention
Embodiment 1:
Take Pseudobulbus Cremastrae Seu Pleiones 9 grams, Radix Sophorae Tonkinensis 10 grams, Herba Senecionis Scandentis 9 grams, Herba Potentillae Discoloris 9 grams, Radix Isatidis 10 grams, FRUCTUS TERMINALIAE IMMATURUS 10 grams, Herba Lophatheri 9 grams, Flos Plumeriae Acutifoliae 10 grams, Folium Microcoris paniculatae 10 grams, bitter 6 grams of three bifurcations, Radix Alangii 6 grams, Myrrha 10 grams, Rhizoma Corydalis 6 grams, Olibanum 6 grams, Radix Cyathulae 10 grams, Caulis Spatholobi 9 grams, Flos Rosae Chinensis 16 grams, Radix Polygalae fallacis 10 grams, Flos Campsis 9 grams, Spina Gleditsiae 6 grams, Fructus Cnidii 8 grams, cleans up above-mentioned raw materials, makes unguentum by conventional method.
Usage and dosage: by prepared external application of ointment in affected part, every day two to three times.
Embodiment 2:
Take Pseudobulbus Cremastrae Seu Pleiones 26 grams, Radix Sophorae Tonkinensis 25 grams, Herba Senecionis Scandentis 28 grams, Herba Potentillae Discoloris 26 grams, Radix Isatidis 25 grams, FRUCTUS TERMINALIAE IMMATURUS 26 grams, Herba Lophatheri 25 grams, Flos Plumeriae Acutifoliae 26 grams, Folium Microcoris paniculatae 21 grams, bitter 25 grams of three bifurcations, Radix Alangii 26 grams, Myrrha 26 grams, Rhizoma Corydalis 21 grams, Olibanum 9 grams, Radix Cyathulae 26 grams, Caulis Spatholobi 26 grams, Flos Rosae Chinensis 35 grams, Radix Polygalae fallacis 26 grams, Flos Campsis 25 grams, Spina Gleditsiae 26 grams, Fructus Cnidii 24 grams, cleans up above-mentioned raw materials, makes unguentum by conventional method.
Usage and dosage: by prepared external application of ointment in affected part, every day two to three times.
Embodiment 3:
Take Pseudobulbus Cremastrae Seu Pleiones 16 grams, Radix Sophorae Tonkinensis 15 grams, Herba Senecionis Scandentis 21 grams, Herba Potentillae Discoloris 18 grams, Radix Isatidis 17 grams, FRUCTUS TERMINALIAE IMMATURUS 19 grams, Herba Lophatheri 21 grams, Flos Plumeriae Acutifoliae 20 grams, Folium Microcoris paniculatae 16 grams, bitter 19 grams of three bifurcations, Radix Alangii 21 grams, Myrrha 18 grams, Rhizoma Corydalis 16 grams, Olibanum 7 grams, Radix Cyathulae 20 grams, Caulis Spatholobi 21 grams, Flos Rosae Chinensis 25 grams, Radix Polygalae fallacis 18 grams, Flos Campsis 21 grams, Spina Gleditsiae 20 grams, Fructus Cnidii 19 grams, cleans up above-mentioned raw materials, makes unguentum by conventional method.
Usage and dosage: by prepared external application of ointment in affected part, every day two to three times.
Claims (3)
1. the Chinese medicine treating the scleroma of hemodialysis patients vascular access local, it is characterized by, it is made up of the raw material of following parts by weight: Pseudobulbus Cremastrae Seu Pleiones 9-26 gram, Radix Sophorae Tonkinensis 10-25 gram, Herba Senecionis Scandentis 9-28 gram, Herba Potentillae Discoloris 9-26 gram, Radix Isatidis 10-25 gram, FRUCTUS TERMINALIAE IMMATURUS 10-26 gram, Herba Lophatheri 9-25 gram, Flos Plumeriae Acutifoliae 10-26 gram, Folium Microcoris paniculatae 10-21 gram, three hardship 6-25 gram of bifurcations, Radix Alangii 6-26 gram, Myrrha 10-26 gram, Rhizoma Corydalis 6-21 gram, Olibanum 6-9 gram, Radix Cyathulae 10-26 gram, Caulis Spatholobi 9-26 gram, Flos Rosae Chinensis 16-35 gram, Radix Polygalae fallacis 10-26 gram, Flos Campsis 9-25 gram, Spina Gleditsiae 6-26 gram, Fructus Cnidii 8-24 gram.
2. a kind of Chinese medicine treating the scleroma of hemodialysis patients vascular access local according to claim 1, is characterized by, be made up of the raw material of following parts by weight: Pseudobulbus Cremastrae Seu Pleiones 9 grams, Radix Sophorae Tonkinensis 10 grams, Herba Senecionis Scandentis 9 grams, Herba Potentillae Discoloris 9 grams, Radix Isatidis 10 grams, FRUCTUS TERMINALIAE IMMATURUS 10 grams, Herba Lophatheri 9 grams, Flos Plumeriae Acutifoliae 10 grams, Folium Microcoris paniculatae 10 grams, bitter 6 grams of three bifurcations, Radix Alangii 6 grams, Myrrha 10 grams, Rhizoma Corydalis 6 grams, Olibanum 6 grams, Radix Cyathulae 10 grams, Caulis Spatholobi 9 grams, Flos Rosae Chinensis 16 grams, Radix Polygalae fallacis 10 grams, Flos Campsis 9 grams, Spina Gleditsiae 6 grams, Fructus Cnidii 8 grams.
3. a kind of Chinese medicine treating the scleroma of hemodialysis patients vascular access local according to claim 1, it is characterised in that: described Chinese medicine is unguentum.
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