CN104225094A - Traditional Chinese medicine preparation for treating Behcet's syndrome - Google Patents
Traditional Chinese medicine preparation for treating Behcet's syndrome Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating Behcet's syndrome. The traditional Chinese medicine preparation is characterized in that the chosen traditional Chinese medicine raw materials are as follows in parts by weight: 8 parts of radix glycyrrhizae, 10 parts of phellodendron amurense, 15 parts of radix sophorae flavescentis, 15 parts of gentian, 35 parts of taraxacum, 12 parts of rheum officinale, 12 parts of radix bupleuri, 12 parts of folium mori, 10 parts of feverfew, 30 parts of bunge corydalis herb, 30 parts of radix rehmanniae recen and 15 parts of angelica. According to the invention, medical properties and effects of the chosen raw medicinal materials are complementary, mutual-inhibition, mutual-restraint and mutual-detoxication in the compatibility of medicines are avoided, so as to achieve remarkable mutual-promotion and mutual-enhancement effects of the medicines and to boost immunity; the preparation has the efficacies of clearing heat to relieve internal heat, nourishing yin to detoxicate and promoting diuresis to disperse stasis and is an oral administration preparation for treating Behcet's syndrome, which is purely prepared from Chinese herbal medicines.
Description
Technical field
The present invention relates to field of traditional Chinese, be specifically related to a kind of Chinese medicine preparation being used for the treatment of behcet syndrome, there is clearing heat, purging intense-heat, YIN nourishing removing toxic substances, dampness removing lead to effect of the stasis of blood.
Background technology
Behcet syndrome, with oral ulcer, genital ulcer and uvea scorching chronic, recurrent disease for main clinical manifestation, involves the chronic disease of multiple system.The state of an illness is recurrent exerbation and alleviates alternation procedure.Some patients lose have visual disorder, minority because of outside visceral injury death, the prognosis bona of most of patient.The generation of behcet syndrome and environment, immunity, trace element, hormone and inherited genetic factors and primary disease and develop relevant.Main clinical manifestation: oral ulcer, pudendal ulcer, uveitis.Dermatosis, gastrointestinal disease, vascular lesion, pulmonary lesion, arthritis, urinary system disease, nervous system lesion.
Summary of the invention:
The object of the present invention is to provide a kind of Chinese medicine preparation being used for the treatment of behcet syndrome, there is clearing heat, purging intense-heat, YIN nourishing removing toxic substances, dampness removing lead to effect of the stasis of blood.
Present invention employs following technical scheme for achieving the above object: the medical material that Chinese medicine preparation of the present invention is selected and weight portion respectively: 8 parts, Radix Glycyrrhizae, Cortex Phellodendri 10 parts, Radix Sophorae Flavescentis 15 parts, Radix Gentianae 15 parts, Herba Taraxaci 35 parts, Radix Et Rhizoma Rhei 12 parts, Radix Bupleuri 12 parts, 12 parts, Folium Mori, Flos Chrysanthemi 10 parts, Herba Violae 30 parts, Radix Rehmanniae 30 parts, Radix Angelicae Sinensis 15 parts.
In the raw material of Chinese medicine that the present invention selects: Radix Glycyrrhizae: property is put down, sweet in the mouth.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong, in the traditional Chinese medical science, Radix Glycyrrhizae invigorating the spleen and replenishing QI, relieving cough and moistening lung, emergency is detoxified, and is in harmonious proportion hundred medicines.
Cortex Phellodendri: [meridian distribution of property and flavor] is bitter, cold.Return kidney, bladder, large intestine channel.[function with cure mainly] heat clearing and damp drying, eliminating fire and detoxication, except hectic fever due to YIN-deficiency clearind deficient heat.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.[chemical composition] Cortex Phellodendri is mainly containing berberine about 1.6%, still appoint alkali, candicine, magnoline, limonin etc. containing palmatine, phellodendrine, jateorhizine, obacunone, Caulis menispermi. root bark isolates berberine about 9%, still containing jateorhizine, phellodendrine, candicine; Cortex Phellodendri content of berberine is higher, reaches 3%; [antibacterial action] Cortex Phellodendri antibiotic effective ingredient is berberine. Cortex Phellodendri decoct or the in vitro tests of alcohol preserved material all have inhibitory action to staphylococcus aureus, Staphylococcus albus, Staphylococcus citreus, Diplococcus pneumoniae, meningococcus, Streptococcus viridans, vibrio cholera, diphtheria corynebacterium, dysentery bacterium, bacillus pyocyaneus etc., nearly unavailable to escherichia coli, Bacillus typhi.
Radix Sophorae Flavescentis: the effect with anti-inflammation, all has inhibitory action to Propiobacterium, staphylococcus aureus, escherichia coli, can diuresis, antiallergic, ease pain, relieving asthma, eliminate the phlegm, [nature and flavor] bitter in the mouth; Cold in nature.[return through] liver; Kidney; Large intestine; Small intestine meridian; Bladder; Heart channel; Urinary bladder channel.[effect] 1, heat clearing and damp drying: extensive use and multiple humidifier fever, as damp-heat dysentery external can decoct soup washout, for hemorrhoid, women gynecological.2, parasite killing (external), diuresis.
Radix Gentianae: the effect with heat clearing away, eliminating pathogen in the liver, arresting convulsion.Compendium of Material Medica is recorded: " nature and flavor are bitter, puckery, Great Cold, nontoxic.Cure mainly cold and heat between bone, frightened pathogenic factor gas, continue wound absolutely, determines the five internal organs, parasite killing poison.Function cures mainly: heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire.For jaundice due to damp-heat, swelling of the vulva pudendal pruritus, leukorrhagia, persistent erection of the penis, eczema pruritus, conjunctival congestion, deaf, hypochondriac pain, bitter taste, convulsion with spasms.
Herba Taraxaci: [nature,taste and action]: sweet, micro-hardship, cold.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.[curing mainly]: upper respiratory tract infection, eye conjunctivitis, mumps, hyperglycemia, acute mastitis swells and ache, gastritis, dysentery, hepatitis, gallbladder assists inflammation, acute appendicitis, urinary system infection, pelvic inflammatory disease, carbuncle furuncle furuncle, pharyngitis, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, urinary tract infection.Containing taraxasterol (Taraxasterol), choline (Choline), inulin (Inulin), pectin (Pectin); Taraxol (Taraxol), stigmasterol (Stigmasterol), β-Amyrin (β-Amyrin), cupreol (β-Sitosterol), taraxerol (taraxerol), taraxacin (Taraxacerin), taraxacin (Taraxacin) and vitamin A, B, C etc.
Radix Et Rhizoma Rhei: meridian distribution of property and flavor: bitter in the mouth, cold in nature.Return stomach, spleen, large intestine, liver, pericardium channel.Function cures mainly: have purging heat to relax the bowels effect, and, constipation, abdominal part distension, pain with tenderness, even hyperpyrexia, unconsciousness and delirium stagnant for Gastrointestinal excess heat, as DACHENGQI TANG; Or the cold accumulation and constipation of spleen YANG deficiency, as wenpi decoction.Removing toxicity for eliminating carbuncles effect, for pathopyretic ulcer, sudden and violent acute conjunctivitis pain, aphtha of the mouth and tongue, gingivitis, as Dahuang Mudan skin soup.Clots absorbing stimulates the menstrual flow effect, for the menstruation apolipsis of stagnation of blood stasis, postpartum stagnation, lump in the abdomen, and traumatic injury, swelling and pain due to blood stasis.Removing damp-heat effect, for jaundice, dysuria, the constipation with dry stool of stagnation of damp-heat; Pyretic stranguria, stranguria caused by urinary stone are as BAZHENG SAN.Also can cooling blood for hemostasis, for injury of blood collaterals by heat haematemesis, epistaxis, have blood in stool, metrorrhagia, leucorrhea with red and white discharge.Modern clinic can be used for treatment epidemic cerebrospinal meningitis, lobar pneumonia, acute biliary infection, acute parotitis, acute appendicitis, Fiedeler's disease type hepatitis, acute enteritis, bacillary dysentery, digestive tract hemorrhage, pharyngolaryngitis, gingival abscess, dermatitis, eczema, gonorrhea, herpes zoster etc.
Radix Bupleuri: clearind deficient heat Chinese medicine, comes off for cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterus, menoxenia.Meridian distribution of property and flavor: cold nature, bitter in the mouth, pungent, return Liver Channel, lung meridian, spleen channel.Function: expelling pathogenic factors from the exterior expels the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.Cure mainly: cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, uterus comes off, menoxenia.
Folium Mori: nature and flavor: bitter in the mouth, sweet, cold in nature.Return lung, Liver Channel.Effect: dispelling wind and heat pathogens; Lung heat clearing; Improving eyesight.Main anemopyretic cold; Pathogenic wind-warm from the beginning of, fever and headache, perspiration and aversion to wind, cough chest pain; Or dryness of the lung dry cough without phlegm; Dry throat and mouth; Wind heat and liver-yang are disturbed; Conjunctival congestion and swelling pain.For anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted.
Flos Chrysanthemi: effectively effect of dispelling wind and heat pathogens, suppressing the hyperactive liver improving eyesight, heat-clearing and toxic substances removing, Flos Chrysanthemi has that treatment anemopyretic cold, fever and headache, conjunctival congestion are dim-sighted, secretly dim-sighted, the dizzy frightened wind action of deficiency of the liver and kindey, order.Nature and flavor: pungent, sweet, bitter, are slightly cold; Gui Jing: return lung, Liver Channel.Effect: effect dispelling wind and heat pathogens, suppressing the hyperactive liver improving eyesight, heat-clearing and toxic substances removing.Cure mainly: anemopyretic cold, fever and headache, conjunctival congestion is dim-sighted, deficiency of the liver and kindey, and order is secretly dim-sighted, dizzy infantile convulsion, controls excessive rising of liver-YANG, has a headache dizzy, kind wind and heat dispersing, purging liver-fire, holding concurrently can tonifying YIN improving eyesight, therefore availablely controls wind-heat of liver channel, or liver-fire is attacked caused conjunctival congestion and swelling pain, the effect of long memorial wind liver heat removing and eyesight improving altogether; Heat-clearing and toxic substances removing, outstanding kind separates furunculosis, therefore availablely controls furuncle swelling toxin.
Herba Violae: cold in nature, bitter in the mouth, mild toxicity [return through]: " plateau Chinese herbal treatment handbook ": " enter the heart, spleen channel." [curative effect of medication] has the effect of heat-clearing and toxic substances removing, promoting blood circulation and detumescence.There is heat-clearing toxin-expelling functions.Cure mainly: influenza; Upper respiratory tract infection, tonsillitis; The high heat of epidemic febrile disease is irritated, influenza, infectious hepatitis, and intestinal is scorching; Nephritis, dysentery; Scrofula, conjunctivitis; Parotitis, acute appendicitis; Furuncle and other pyogenic infection; [chemical composition]: containing more than 10 kinds of alkaloids.From wherein obtaining Herba Corydalis Bungeanae A prime, B prime, C prime and D prime (temporary name) 4 kinds of different alkaloids.Another containing Coumarins lactone, steroid saponin, phenolic substance, resinene and volatilization wet goods;
Radix Rehmanniae: sweet in the mouth, hardship, cold in nature. enter the heart, liver, kidney channel.[effect] clearing away heat and promoting production of body fluid YIN nourishing, nourishes blood.[curing mainly] controls fever due to yin deficiency, quenches one's thirst, and spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon hinders constipation.Clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid; For calentura excessive thirst, send out speckle dermexanthesis, yin asthenia generating intrinsic heat, haematemesis, epistaxis, diabetes, infectious hepatitis.
Radix Angelicae Sinensis: [chemical composition] is containing basic lactone, n-butene acyl lactone, ferulic acid, nicotinic acid, sucrose and several amino acids, and sesquiterpenoids etc.[meridian distribution of property and flavor] is warm in nature, hides sweet, pungent.Return liver, the heart, spleen channel.[function cures mainly] is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Raw medicinal material property of medicine effect selected by the present invention is complementary, has evaded the choosing of the mutual inhibition of compatibility between medicine, mutual restraint between two drugs, the mutual-detoxication, makes medicine mutual reinforcement between, mutual-assistance effect significantly, has the effect of enhancing immunity.There is clearing heat, purging intense-heat, YIN nourishing removing toxic substances, dampness removing leads to effect of the stasis of blood, is that for oral administration pure Chinese herbal medicine for the treatment of behcet syndrome forms preparation.There is during clinical practice good precise effects.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations.Such as these crude drug pulverize mix homogeneously powder can be taken after mixing it with water; Can by these crude drug together decocting, then concentrated decocting liquid is taken, or concentrated decocting liquid is condensed into cream is processed into pill and takes; In order to make each raw material of this medicine play drug effect better, carry out special extraction for certain crude drug, as ethanol extraction, these can not be used for limiting the scope of the invention.
Medicine of the present invention has clearing heat, purging intense-heat, YIN nourishing removing toxic substances, dampness removing lead to effect of the stasis of blood, is used for the treatment of behcet syndrome.The present inventor through repeatedly studying, and passes through the checking repeatedly of clinical trial, finally have found the endo-medicine of better curative effect, thus completes the present invention.
Clinical test of pesticide effectiveness material and model case:
1. an XX, female, 37 years old.Hold a consultation July 10 2009 date.
Patient is in October, 2008, and start to play the large ulcer surface of beans in tongue body both sides, ache influence appetite, does not heal for a long time.In May, 2009 also there is multiple ulcer, pain in external genital, inconvenience of walking.Feel that blurred vision is unclear simultaneously.Check at certain hospital admission: conjunctival congestion.Tongue two takes up external genital multiple ulcer, little of the grain of rice is greatly to Semen Glycines.Surface is with white exudate, and pain is touched more so.Heavy time light during the state of an illness, prolongedly not heal.Be diagnosed as behcet syndrome.Go to a doctor in Lai in July 10 the court in 2009.Patient's bitter taste is indigestion and loss of appetite, general weakness, yellowish or reddish urine.Red tongue, yellow and greasy fur, pulse condition stringy and rolling pulse.This belongs to liver and gall excess-fire, and caused by dampness-heat of the liver fills the air, control suitable clearing away heat-fire, YIN nourishing is detoxified.After clothes we 20 doses, tongue and vulval ulcer face take a turn for the better to some extent.Continue to take we after 1 month, heal completely in tongue and vulval ulcer face, tongue arteries and veins is normal, and disease is fully recovered.
Method and effective dose: 8 parts, Radix Glycyrrhizae, Cortex Phellodendri 10 parts, Radix Sophorae Flavescentis 15 parts, Radix Gentianae 15 parts, Herba Taraxaci 35 parts, Radix Et Rhizoma Rhei 12 parts, Radix Bupleuri 12 parts, 12 parts, Folium Mori, Flos Chrysanthemi 10 parts, Herba Violae 30 parts, Radix Rehmanniae 30 parts, Radix Angelicae Sinensis 15 parts; Get prescription ormal weight tcm and herbal slice, put in suitable decocting device, add clear water appropriate, soak suitable time, be heated to boil, keep slight boiling condition certain hour (about 25 ~ 30 minutes), be separated fried liquid, medicinal residues add water and decoct in right amount, after regulation decoction 2 ~ 3 times, merge fried liquid, filter or settlement separate fried liquid for.
Decoction oral is main, and every day takes orally for 2 times sooner or later, each 150ml decoction being taken warmly.Decoction then acts on fast and power is high, is adapted to the more anxious severe one of the state of an illness.As lighter in the state of an illness or slow person, is preferably that pill is for oral administration asks its merit.
Detailed description of the invention
The described Chinese medicine preparation being used for the treatment of behcet syndrome, it is characterized in that, the raw material of Chinese medicine of selection and weight portion respectively: 8 parts, Radix Glycyrrhizae, Cortex Phellodendri 10 parts, Radix Sophorae Flavescentis 15 parts, Radix Gentianae 15 parts, Herba Taraxaci 35 parts, Radix Et Rhizoma Rhei 12 parts, Radix Bupleuri 12 parts, 12 parts, Folium Mori, Flos Chrysanthemi 10 parts, Herba Violae 30 parts, Radix Rehmanniae 30 parts, Radix Angelicae Sinensis 15 parts;
Preparation method: extracting liquorice 8 parts, Cortex Phellodendri 10 parts, Radix Sophorae Flavescentis 15 parts, Radix Gentianae 15 parts, Herba Taraxaci 35 parts, Radix Et Rhizoma Rhei 12 parts, Radix Bupleuri 12 parts, 12 parts, Folium Mori, Flos Chrysanthemi 10 parts, Herba Violae 30 parts, Radix Rehmanniae 30 parts, Radix Angelicae Sinensis 15 parts; Make decoction pieces respectively, put in suitable decocting device, add clear water appropriate, soak suitable time, be heated to boil, keep slight boiling condition certain hour (about 25 ~ 30 minutes), be separated fried liquid, medicinal residues add water and decoct in right amount, after regulation decoction 2 ~ 3 times, merge fried liquid, filter or settlement separate fried liquid for.
Claims (1)
1. be used for the treatment of the Chinese medicine preparation of behcet syndrome, it is characterized in that, the raw material of Chinese medicine of selection and weight portion respectively: 8 parts, Radix Glycyrrhizae, Cortex Phellodendri 10 parts, Radix Sophorae Flavescentis 15 parts, Radix Gentianae 15 parts, Herba Taraxaci 35 parts, Radix Et Rhizoma Rhei 12 parts, Radix Bupleuri 12 parts, 12 parts, Folium Mori, Flos Chrysanthemi 10 parts, Herba Violae 30 parts, Radix Rehmanniae 30 parts, Radix Angelicae Sinensis 15 parts;
It is characterized in that:
Its preparation method: extracting liquorice 8 parts, Cortex Phellodendri 10 parts, Radix Sophorae Flavescentis 15 parts, Radix Gentianae 15 parts, Herba Taraxaci 35 parts, Radix Et Rhizoma Rhei 12 parts, Radix Bupleuri 12 parts, 12 parts, Folium Mori, Flos Chrysanthemi 10 parts, Herba Violae 30 parts, Radix Rehmanniae 30 parts, Radix Angelicae Sinensis 15 parts; Make decoction pieces respectively, put in suitable decocting device, add clear water appropriate, soak suitable time, be heated to boil, keep slight boiling condition certain hour (about 25 ~ 30 minutes), be separated fried liquid, medicinal residues add water and decoct in right amount, after regulation decoction 2 ~ 3 times, merge fried liquid, filter or settlement separate fried liquid for.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105232756A (en) * | 2015-11-23 | 2016-01-13 | 李先强 | Traditional Chinese medicine for treating behcet syndromes |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232756A (en) * | 2015-11-23 | 2016-01-13 | 李先强 | Traditional Chinese medicine for treating behcet syndromes |
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Application publication date: 20141224 |