CN104740211A - Traditional Chinese medicine composition for treating varicose vein of lower limbs and preparation method for traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for treating varicose vein of lower limbs and preparation method for traditional Chinese medicine composition Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating varicose vein of lower limbs. The traditional Chinese medicine composition is prepared from the following main raw materials in parts by weight: 10-20 parts of Chinese angelica, 10-25 parts of dioscorea nipponica makino, 5-15 parts of pangolins, 15-25 parts of oysters, 3-8 parts of red flowers, 12-24 parts of rhizoma corydalis, 20-30 parts of phryma leptostachya, 20-40 parts of pseudo-ginseng, 13-27 parts of radix achyranthis bidentatae, 4-17 parts of dysosma versipellis, 10-15 parts of ligusticum wallichii, 4-10 parts of huperzia serrata, 15-25 parts of securinega suffruticosa and 15-20 parts of manyleaf paris rhizome. The traditional Chinese medicine composition disclosed by the invention is remarkable in effect of treating varicose vein of lower limbs, and has the effects of promoting blood circulation to remove blood stasis, relaxing the muscles and stimulating the blood circulation, recuperating gas-blood and improving the long-term illness of the patient due to the varicose vein of lower limbs. The traditional Chinese medicine composition selects normal local medical raw materials with low price, so that the economic burden of the patient is relieved.
Description
Technical field
The invention discloses a kind of Chinese medicine composition, especially a kind of Chinese medicine composition for the treatment of varicose veins of the lower extremity and preparation method thereof, the invention belongs to traditional Chinese medicine field.
Background technology
The varicose of pure superficial veins of lower limb refers to the pathological changes person that is only confined to superficial veins of lower limb, and its extent of disease comprises great saphenous vein, small saphenous vein and branch thereof, and most humans all occurs in great saphenous vein, and clinical diagnosis is great saphenous varicose vein.The superficial vein of pathological changes shows as elongation, expansion and sinuous flexing, and multiple being born in is engaged in the work of standing and blue-collar crowd lastingly.The pure superficial veins of lower limb varicose state of an illness is general comparatively light, and operative treatment often can obtain good effect.How due to the superficial vein blood flow reflux that superficial vein first pair of valve (stock saphena valve) incompetence causes, increase veins of lower extremity pressure and cause.Secondly, geneogenous wall of vein weakness is also major reason, and patient is often associated with the whole body or circumscribed wall of vein defect, when vein pressure increases, just produces tortuous, the expansion of vein.Finally, stand for a long time, fat and abdominal pressure etc. because of procatarxis can increase that vein pressure all can increase that varicosis development occurs may.
Clinical manifestation: morbidity is early stage, mostly is the lower limb swollen discomfort of acid and dull pain sense, has limbs sense of heaviness simultaneously, easily weak.How above-mentionedly behind station for a long time feel to increase the weight of, then can be alleviated by flat sleeping, limb lifting.Pathological changes middle and late stage, wall of vein is impaired, vein protuberance, expansion, tortuous, in Lumbricus sample outward appearance, with the traveling of medial leg great saphenous vein, district is obvious.Course of disease elder, limb skin then occurs that trophism changes, and as desquamation, pruritus, pigmentation etc., even forms eczema and ulcer.Along with the differentiation of the state of an illness, can with the symptom such as pain, lower extremity swelling and distension, stasis dermatitis, superficial vein thrombosis of blood vessel traveling.Superficial veins of lower limb varicose has obvious morphological characteristic, namely can be clarified a diagnosis by general physical examination.After standing, superficial veins of lower limb projection, namely points out cirsoid possibility.To fully understand the state of an illness further, then needing to carry out detailed physical examination further, understanding vein valve function situation and the unobstructed situation of Deep venou, needing if desired to carry out intravenous or contrast examination.The varicosis that emphasis should cause with deep venous thrombosis sequela is differentiated mutually, and the latter has deep venous thrombosis medical history, and lower limb have the performance of obvious tumefaction more.As lower limb You Xue district ulcer, severe dermatitis etc., should be noted that communicating veins is with or without getting involved.
In the method for existing treatment varicose veins of the lower extremity, Authorization Notice No. CN 103330780 B(application number 201310317486.7) disclose a kind of medicine for the treatment of varicose veins of the lower extremity, it is characterized in that: it is made up of the crude drug in following weight range: Radix Rehmanniae 25-35 grams, 10-20 grams, Flos Carthami, Fructus Aurantii 8-15 grams, the Radix Astragali 15-25 grams, Radix Sophorae Flavescentis 25-35 grams, Cortex Dictamni 8-15 grams, Herba Portulacae 8-15 grams, Rhizoma Atractylodis 10-20 grams, Cortex Phellodendri 10-20 grams, Lumbricus 8-15 grams, Radix Paeoniae Rubra 8-15 grams, Radix Bupleuri 5-10 grams, Rhizoma Chuanxiong 8-15 grams, Radix Angelicae Sinensis 10-20 grams.Authorization Notice No. CN 103099996 B(application number 201210558994.X) patent discloses a kind of Chinese medicine composition for the treatment of varicose veins of the lower extremity, it is characterized in that being made up of the crude drug of following weight parts: Fructus Gardeniae 12, Fructus Chaenomelis 10, Caulis Trachelospermi 12, Caulis Spatholobi 15, Cortex Lycii 15, Herba Portulacae 15, Radix Arnebiae (Radix Lithospermi) 12, Herba Lycopodii 10, Radix Achyranthis Bidentatae 15, Radix Trichosanthis 12, Pheretima 8, Semen Coicis 8, Ramulus Cinnamomi 12, Semen Persicae 15.
Chinese medicine occupies very consequence in treatment varicose veins of the lower extremity as can be seen here, but its main dosage form of existing patent is decoction, and it is desirable that the effect for treatment varicose veins of the lower extremity is also not so good as compositions, can cause extra burden to the health of patient.
Summary of the invention
For the present situation of existing treatment varicose veins of the lower extremity deficiency, an object of the present invention is to provide a kind of Chinese medicine composition for the treatment of varicose veins of the lower extremity, have easy to carry, action effect is obvious, the effect playing blood circulation promoting and blood stasis dispelling that can be very fast, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned Chinese medicine composition.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat a Chinese medicine composition for varicose veins of the lower extremity, take off the primary raw material stating weight proportion and be prepared from: Radix Angelicae Sinensis 10-20 part, Rhizoma Dioscoreae Nipponicae 10-25 part, Squama Manis 5-15 part, Concha Ostreae 15-25 part, Flos Carthami 3-8 part, Rhizoma Corydalis 12-24 part, Herba speranskiae tuberculatae 20-30 part, Radix Notoginseng 20-40 part, Radix Achyranthis Bidentatae 13-27 part, Radix et Rhizoma Dysosmatis 4-17 part, Rhizoma Chuanxiong 10-15 part, Herba Lycopodii serrati 4-10 part Cacumen Securinegae Suffruticosae 15-25 part, Rhizoma Paridis 15-20 part.
Treat a Chinese medicine composition for varicose veins of the lower extremity, optimum ratio, take off the primary raw material stating weight proportion and be prepared from: Radix Angelicae Sinensis 13-18 part, Rhizoma Dioscoreae Nipponicae 14-20 part, Squama Manis 8-13 part, Concha Ostreae 18-23 part, Flos Carthami 4-6 part, Rhizoma Corydalis 16-20 part, Herba speranskiae tuberculatae 23-28 part, Radix Notoginseng 25-35 part, Radix Achyranthis Bidentatae 15-25 part, Radix et Rhizoma Dysosmatis 7-10 part, Rhizoma Chuanxiong 11-14 part, Herba Lycopodii serrati 6-8 part, Cacumen Securinegae Suffruticosae 18-23 part, Rhizoma Paridis 16-19 part.
Treat a Chinese medicine composition for varicose veins of the lower extremity, better preferred proportioning, take off the primary raw material stating weight proportion and be prepared from: Radix Angelicae Sinensis 15 parts, Rhizoma Dioscoreae Nipponicae 17 parts, Squama Manis 10 parts, Concha Ostreae 20 parts, 5 parts, Flos Carthami, Rhizoma Corydalis 18 parts, Herba speranskiae tuberculatae 25 parts, 30 parts, Radix Notoginseng, Radix Achyranthis Bidentatae 20 parts, Radix et Rhizoma Dysosmatis 9 parts, Rhizoma Chuanxiong 13 parts, Herba Lycopodii serrati 7 parts, Cacumen Securinegae Suffruticosae 20 parts, Rhizoma Paridis 17 parts.
The preparation method of above-mentioned Chinese medicine composition, preparation process is as follows:
(1) Radix Angelicae Sinensis, Radix Notoginseng, Herba Lycopodii serrati and Rhizoma Chuanxiong are eluriated 2-6 time, be placed in shady and cool ventilation place ventilation 10-20 hour, pressure cooker is put in chopping, a longer leather hose having certain degree of hardness is connected in gas outlet, then section leather hose of is wherein immersed in cold water and cool, another section of leather hose connects a carafe, is then separated the oil on upper strata, and the oil separated is exactly Mixed chaotic sequences;
(2) Flos Carthami and Rhizoma Paridis are cleaned the spray of chopping yellow wine even, sealing and standing 2-4 days, extrudes yellow wine and obtains processed with wine Flos Carthami and Rhizoma Paridis;
(3) Concha Ostreae is placed in boiled hot water, boils 1-3 minute, taking-up is dried in the air cool, is taken out by Carnis ostreae, is cut into block, is placed in parch 3-7 minute in pot, grinds into powder stand-by;
(4) cleaned by Squama Manis, with rice vinegar bubble 4-8 hour, it is crisp to be placed in forging on smokeless stove fire, and grinding into smalls into powder, to cross 80-120 mesh sieve stand-by;
(5) Rhizoma Dioscoreae Nipponicae, Rhizoma Corydalis, Herba speranskiae tuberculatae, Radix Achyranthis Bidentatae, Radix et Rhizoma Dysosmatis and Cacumen Securinegae Suffruticosae are placed in marmite the water adding raw material gross weight 4-6 times; intense fire is fried open; add processed with wine Flos Carthami and Rhizoma Paridis after turning slow fire boiling 10-20 minute, big fire is heated to boiling, ceases fire after 2-8 minute until boiling; filter; filtrate is dried in the air to during room temperature and is dropped into step (3) and (4) gains, and big fire decocts to boiling, ceases fire after stirring 2-4 minute with large ferrum spoon; leave standstill 7-9 hour, get supernatant loading air-tight bottle and namely obtain oral liquid medicine.
Above-mentioned preparation method, Radix Angelicae Sinensis, Radix Notoginseng, Herba Lycopodii serrati and Rhizoma Chuanxiong are eluriated 3-5 all over (preferred, Radix Angelicae Sinensis, Radix Notoginseng, Herba Lycopodii serrati and Rhizoma Chuanxiong are eluriated 4 times) by step (1).
Above-mentioned preparation method, step (1) is placed in the ventilation of shady and cool ventilation place 13-18 hour (preferred, to be placed in shady and cool ventilation place and to ventilate 15 hours).
Above-mentioned preparation method, Carnis ostreae takes out by step (3), is cut into block, to be placed in pot parch 4-6 minute (preferred, to be taken out by Carnis ostreae, be cut into block, to be placed in pot parch 5 minutes).
Above-mentioned preparation method, Squama Manis is cleaned by step (4), with rice vinegar bubble 5-7 hour (preferred, to be cleaned by Squama Manis, steep 6 hours with rice vinegar).
Above-mentioned preparation method, Rhizoma Dioscoreae Nipponicae, Rhizoma Corydalis, Herba speranskiae tuberculatae, Radix Achyranthis Bidentatae, Radix et Rhizoma Dysosmatis and Cacumen Securinegae Suffruticosae are placed in marmite and add raw material gross weight 4.5-5.5 water doubly (preferred, Rhizoma Dioscoreae Nipponicae, Rhizoma Corydalis, Herba speranskiae tuberculatae, Radix Achyranthis Bidentatae, Radix et Rhizoma Dysosmatis and Cacumen Securinegae Suffruticosae to be placed in marmite the water adding raw material gross weight 5 times) by step (5).
Above-mentioned preparation method, step (5) adds processed with wine Flos Carthami and Rhizoma Paridis (preferred, to turn slow fire boiling and add processed with wine Flos Carthami and Rhizoma Paridis after 15 minutes) after turning slow fire boiling 13-18 minute.
Using method: for making the present invention reach optimum therapeuticing effect, the volatile oil made spreads upon affected part on 1st for several times, and suitable massage, each 5-10ml of oral liquid, after breakfast, lunch and dinner, half an hour takes.
This Chinese medicine composition, can also relaxing muscles and tendons to promote blood circulation to the Be very effective of varicose veins of the lower extremity, not only blood circulation promoting and blood stasis dispelling, QI and blood regulating, improves patient for a long time because of the slight illness that varicose veins of the lower extremity brings, and the local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
Treat a Chinese medicine composition for varicose veins of the lower extremity, the pharmacological effect of each crude drug is respectively:
Radix Angelicae Sinensis: bitter in the mouth, temperature, nontoxic, enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.The all cards of main blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
Cacumen Securinegae Suffruticosae: base is former: be browse or the root of Euphorbiaceae Suffrutescent Securinega Twig platymiscium Suffrutescent Securinega Twig.Composition: Herb contains alkaloid: Securinine, Suffrutescent Securinega Twig alkali.Containing dihydrosecurinine in leaf, securinol A, B, securinol C picrate, Bie Securinine, Securinine; Also containing phenolic constituent: Herba Euphorbiae Helioscopiae tannin B and the nor-Bergeninum of 11-O-galloyl.Containing gallic acid etc. in stem.The property of medicine: pungent, bitter, tepor, slightly poisonous.Function cures mainly: expelling wind and activating blood circulation, the strong muscle of kidney tonifying.Cure mainly lumbago due to pathogenic wind-dampness, sexual impotence, dizzy, tinnitus, deaf, facial paralysis, poliomyelitis sequela.
Rhizoma Dioscoreae Nipponicae: another name Dioscorea nipponica Mak. Ningpo Yam Rhizome, Rhizoma Dioscoreae Nipponicae, Dioscorea nipponica bone, ground joist, Rhizoma Smilacis Bockii, chicken bone, mountain Radix Dichroae, Radix Dichroae, parthenocissus, tip of a whip dish.Flavor efficacy is bitter, flat.Return liver, lung meridian.Function relaxing muscles and tendons to promote blood circulation, timid wind pain relieving, relieving cough and asthma, timid expectorant.Be applicable to lumbago and skelalgia, muscles and bones numbness, traumatic injury, lumbar sprain and QI divergeny, cough pant.
Squama Manis: there is eliminating mass of invigorating blood circulation, stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, effect of expel wind to dredge collateral.For Jing Bi WEIJIA, galactostasis, carbuncle sore tumefacting virus, rheumatic arthralgia, paralysis due to windstroke, numbness contracture.
Concha Ostreae: salty, is slightly cold; Return liver, gallbladder, kidney channel.Function: medicine for calming liver and calming endopathic wind; Yin-nourishing drug.Concha Ostreae (calcined): the effect restraining astringent or styptic treatment for spontaneous sweating deacidification is strong, treatment has a stomach-ache, gastric acid etc.Concha Ostreae: above accept and hold back, treatment is dizzy, just rare.There are convergence, calmness, removing toxic substances, analgesic effect; The acidic extraction thing of Concha Ostreae is inhibited to poliovirus in live body, and the Mus mortality rate of infection is reduced.
Flos Carthami: pungent, temperature, nontoxic, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, contributes to controlling amenorrhea, dysmenorrhea, lochia, obstruction of qi in the chest and cardialgia, the stagnant stomachache of the stasis of blood, the twinge of the breast side of body, traumatic injury, skin infection swells and ache curative effect.Have blood circulation promoting and blood stasis dispelling, wet dissipation goes the effect swollen.
Rhizoma Corydalis: Rhizoma Corydalis acrid in the mouth, hardship, warm in nature.Have promoting blood circulation to remove blood stasis, the function of regulating QI to relieve pain, for whole body each portion qi depression to blood stasis pain, dysmenorrhea, amenorrhea, lump in the abdomen, postpartum stagnation, injury from falling down, hernia is had a pain.
Herba speranskiae tuberculatae: 1. expelling wind and removing dampness, the pungent temperature of these product, Xin Nenghang falls apart, and temperature overcomes the coldness wet.Eight Liver Channel, therefore energy expelling wind and removing dampness, as Compendium of Material Medica is said: Herba speranskiae tuberculatae " controls all rheumatalgia contractures of muscles and bones.If " cause limbs pain because of wind-cold damp pathogen invasion and attack limbs meridians, numb, joint stuffiness.Can select these product, expelling wind and cold victory is wet, and pathogenic factor goes, then all disease spontaneous recovery.2. relaxing muscles and tendons and activating QI and blood in the collateral, the pungent loose temperature of these product is led to, and enters Liver Channel, and liver governing tendons. therefore these product have effect of relaxing muscles and tendons and activating QI and blood in the collateral.For the heresy of affection of exogenous wind-cold, lose a surname through gas, disease is seen that limbs muscle arteries and veins shrinks and is taken out urgency, can not relax and turn freely.Can select Herba speranskiae tuberculatae, expelling wind and cold, relaxing muscles and tendons and activating QI and blood in the collateral controls it.As " the sweet peaceful blue or green Chinese herbal medicine choosing in Shan " namely selects these product, control muscles and bones contracture.3. promoting blood circulation and stopping pain, the pungent loose temperature of these product is led to, and enters Liver Channel blood system, therefore can promoting blood circulation and stopping pain.To upper and lower, trusted subordinate's waist knee joint, inside and outside various pain, all can select these product to control it, and get its pungent temperature and be apt to away, the merit of promoting the circulation of QI of invigorating blood circulation, vim and vigour general rule is not bitterly.4. solution poisons rash, the secret red medicine writing paper of spirit " say: " treat pyretic toxicity." " Yang Cheng Empirical formula " select this product, control toxic swelling from the beginning of." the sweet peaceful blue or green Chinese herbal medicine choosing in Shan " then uses these product, controls eczema scrotum, sore swollen toxin.Therefore Herba speranskiae tuberculatae treatment skin ulcer tinea toxic swelling can be thought, eczema scrotum, general many decoction being used as a lotion.Because this medicine washout also has priming to penetrate meridians, blood vessels, and dispel the wind, invigorate blood circulation, the feature of pain relieving.
Radix Notoginseng: sweet, micro-hardship, temperature.Gui Jing returns liver, stomach warp.Effect dissipating blood stasis stops blooding, subduing swelling and relieving pain.Cure mainly for spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
Radix Achyranthis Bidentatae: root is used as medicine, raw use, promoting blood circulation to restore menstrual flow; Control puerperal abdonimal pain, menoxenia, amenorrhea, epistaxis, toothache caused by fire of deficiency type, beriberi edema; Ripe use, invigorating the liver and kidney, strong waist knee joint; Control soreness of waist and knee joint, caused by liver and kidney deficiency, traumatic injury stasis of blood pain.Veterinary, as controlling cattle weak foot disease, gets injured by a fall knochenbruch etc., nature and flavor: bitter, sweet, sour, flat.Gui Jing: return liver, kidney channel.Effect: eliminating blood stasis and inducing menstruation, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, conducting blood to flow downwards.Cure mainly: for amenorrhea, dysmenorrhea, soreness of waist and knee joint, muscles and bones is unable, stranguria, edema, headache, dizzy toothache, day skin ulcer, spit blood, epistaxis.
Radix et Rhizoma Dysosmatis: Radix et Rhizoma Dysosmatis: base is former: be the root and rhizome of Berberidaceae Dysosma plant Radix et Rhizoma Dysosmatis, Dysosma Pleiantha and dysosma veitchii Fu.Composition: 1. Radix et Rhizoma Dysosmatis rhizome is containing lignanoid: podophyllotoxin, picropodophyllin; Flavonoid: diphyllin kaempferol, Quercetin etc.2. Dysosma Pleiantha rhizome is containing lignanoid: podophyllotoxin, dehydropodophyllotoxin, podophyllotoxone etc.3. dysosma veitchii Fu root is containing deoxypodophyllotoxin ,-peltain, podophyllotoxin, kaempferol-3--D-Glucose glycosides, glucose, sucrose and-sitosterol.The property of medicine: bitter, pungent, temperature.Poisonous.Return lung, Liver Channel.Function cures mainly: removing toxic substances of reducing phlegm, eliminating stasis and resolving masses.Cure mainly cough, laryngopharynx swelling and pain, scrofula, goiter, nameless gall, herpes zoster, venom, traumatic injury, rheumatic arthralgia.
Herba Lycopodii serrati: base is former: be the herb of Huperziaceae plants of Huperzia snake-stone stone China fir.Composition: Herba Lycopodii serrati grass is containing alkaloid: lycopodine, [4aR-(4a.alpha.,5.alpha.,10b.alpha.,12R .), serrate clubmoss herb alkali, lycodoline, excellent lycoclavanin alkali, the peaceful alkali of Herba Lycopodii serrati, its peaceful alkali of Herba Lycopodii serrati, its Buddhist nun of Herba Lycopodii serrati determines alkali, lycoclavine alkali etc.The property of medicine: bitter, pungent, micro-sweet, flat, mild toxicity.Function cures mainly: dissipating blood stasis stops blooding, and removing damp-heat, cures mainly traumatic injury, over-strained hemoptysis, hematuria, hemorrhoid hematochezia, tympanites, leucorrhea, venom, and ulcer does not close up for a long time, burn and scald.
Rhizoma Paridis: base is former: be the rhizome of paris plant China of Radix Angelicae Sinensis section Rhizoma Paridis, Rhizoma Paridis or Rhizoma Paridis.Composition: 1. magnificent rhizoma paris rhizome is containing steroidal saponin :-3-O-α-L-arabinofuranosyl etc.2. Rhizoma Paridis rhizome is containing steroidal saponin: diosgenin-3-O-α-L-rhamnopyranosyl (1 → 2)-[α-L-arabinofuranosyl (1 → 4)]-β-D-pyranglucoside, the black and white aglycon of Rhizoma Dioscoreae-3-O-α-L-rhamnopyranosyloxyhy Tang Ji (1 → 4)-α-L rhamnopyranosyloxyhy Tang Ji (1 → 4)-[α-L-rhamnopyranosyl (1 → 2)-] β-D-pyranglucoside, etc.3. Rhizoma Paridis rhizome is containing body saponin: paris polyphylla saponin A, etc.The property of medicine: bitter, is slightly cold, mild toxicity.Return Liver Channel.Function cures mainly: heat-clearing and toxic substances removing, detumescence arresting convulsion.Cure mainly carbuncle sore tumefacting virus, pharyngeal swelling sore throat, acute mastitis, snake bite and insect sting, traumatic pain, liver-heat is twitched.
Chinese medicine composition of the present invention is based on the principle of traditional Chinese medical herbal treatment varicose veins of the lower extremity.The Chinese medicinal material selected all has blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons to promote blood circulation, effect of regulating the flow of Qi and the middle Jiao, and cheap, and life-time service also can not cause the financial burden of patient, is to treat the ideal medicine of varicose veins of the lower extremity.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1treat a Chinese medicine composition for varicose veins of the lower extremity, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Radix Angelicae Sinensis 10 parts, Rhizoma Dioscoreae Nipponicae 10 parts, Squama Manis 5 parts, Concha Ostreae 15 parts, 3 parts, Flos Carthami, Rhizoma Corydalis 12 parts, Herba speranskiae tuberculatae 20 parts, 20 parts, Radix Notoginseng, Radix Achyranthis Bidentatae 13 parts, Radix et Rhizoma Dysosmatis 4 parts, Rhizoma Chuanxiong 10 parts, Herba Lycopodii serrati 4 parts of Cacumen Securinegae Suffruticosaes 15 parts, Rhizoma Paridis 15 parts.
The preparation method of above-mentioned Chinese medicine composition, step is:
(1) Radix Angelicae Sinensis, Radix Notoginseng, Herba Lycopodii serrati and Rhizoma Chuanxiong are eluriated 2 times, be placed in shady and cool ventilation place to ventilate 10 hours, pressure cooker is put in chopping, a longer leather hose having certain degree of hardness is connected in gas outlet, then section leather hose of is wherein immersed in cold water and cool, another section of leather hose connects a carafe, is then separated the oil on upper strata, and the oil separated is exactly Mixed chaotic sequences;
(2) Flos Carthami and Rhizoma Paridis are cleaned the spray of chopping yellow wine even, sealing and standing 2 days, extrudes yellow wine and obtains processed with wine Flos Carthami and Rhizoma Paridis;
(3) Concha Ostreae is placed in boiled hot water, boils 1 minute, taking-up is dried in the air cool, is taken out by Carnis ostreae, is cut into block, is placed in parch 3-7 minute in pot, grinds into powder stand-by;
(4) cleaned by Squama Manis, steep 4 hours with rice vinegar, it is crisp to be placed in forging on smokeless stove fire, and grinding into smalls into powder, to cross 80 mesh sieves stand-by;
(5) Rhizoma Dioscoreae Nipponicae, Rhizoma Corydalis, Herba speranskiae tuberculatae, Radix Achyranthis Bidentatae, Radix et Rhizoma Dysosmatis and Cacumen Securinegae Suffruticosae are placed in marmite the water adding raw material gross weight 4 times; intense fire is fried open; turn slow fire boiling and add processed with wine Flos Carthami and Rhizoma Paridis after 10 minutes, big fire is heated to boiling, ceases fire after 2 minutes until boiling; filter; filtrate is dried in the air to during room temperature and is dropped into step (3) and (4) gains, and big fire decocts to boiling, ceases fire after stirring 2 minutes with large ferrum spoon; leave standstill 7 hours, get supernatant loading air-tight bottle and namely obtain oral liquid medicine.
model case onewu XX, female, 58 years old, Chiping County, Liaocheng of Shandong Province, in April, 2013 fell ill, symptom: tortuous nearly 15 years of the two lower limb vascular of main cause, more than left lower extremity ulcer January.In more than 15 years of this sufferer of patient's readme, before 15 years, the conscious pair of swollen discomfort of lower limb acid also accompanies slight edema, occurs that two lower limb superficial vein tortuous increasing is slightly in Lumbricus shape simultaneously.Extend right lower extremity malaise symptoms in time to increase the weight of, varix increases the weight of, and horizontal position can relief of symptoms after having a rest, but stands when walking and can rebound, and fails for many years to cure always, starts after being introduced to take medicine of the present invention.
Take embodiment 1 gained Chinese medicine oral liquid and with the use of volatile oil, after 10 days, symptom starts to alleviate, fully recover, use again Chinese medicine composition of the present invention to consolidate 1 month after recovery from illness when 30 days, drug withdrawal is so far without recurring.
embodiment 2treat a Chinese medicine composition for varicose veins of the lower extremity, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Radix Angelicae Sinensis 20 parts, Rhizoma Dioscoreae Nipponicae 25 parts, Squama Manis 15 parts, Concha Ostreae 25 parts, 8 parts, Flos Carthami, Rhizoma Corydalis 24 parts, Herba speranskiae tuberculatae 30 parts, 40 parts, Radix Notoginseng, Radix Achyranthis Bidentatae 27 parts, Radix et Rhizoma Dysosmatis 17 parts, Rhizoma Chuanxiong 15 parts, Herba Lycopodii serrati 10 parts of Cacumen Securinegae Suffruticosaes 25 parts, Rhizoma Paridis 20 parts.
The preparation method of above-mentioned Chinese medicine composition, step is:
(1) Radix Angelicae Sinensis, Radix Notoginseng, Herba Lycopodii serrati and Rhizoma Chuanxiong are eluriated 6 times, be placed in shady and cool ventilation place to ventilate 20 hours, pressure cooker is put in chopping, a longer leather hose having certain degree of hardness is connected in gas outlet, then section leather hose of is wherein immersed in cold water and cool, another section of leather hose connects a carafe, is then separated the oil on upper strata, and the oil separated is exactly Mixed chaotic sequences;
(2) Flos Carthami and Rhizoma Paridis are cleaned the spray of chopping yellow wine even, sealing and standing 4 days, extrudes yellow wine and obtains processed with wine Flos Carthami and Rhizoma Paridis;
(3) Concha Ostreae is placed in boiled hot water, boils 3 minutes, taking-up is dried in the air cool, is taken out by Carnis ostreae, is cut into block, is placed in parch 3-7 minute in pot, grinds into powder stand-by;
(4) cleaned by Squama Manis, steep 8 hours with rice vinegar, it is crisp to be placed in forging on smokeless stove fire, and grinding into smalls into powder, to cross 120 mesh sieves stand-by;
(5) Rhizoma Dioscoreae Nipponicae, Rhizoma Corydalis, Herba speranskiae tuberculatae, Radix Achyranthis Bidentatae, Radix et Rhizoma Dysosmatis and Cacumen Securinegae Suffruticosae are placed in marmite the water adding raw material gross weight 6 times; intense fire is fried open; turn slow fire boiling and add processed with wine Flos Carthami and Rhizoma Paridis after 20 minutes, big fire is heated to boiling, ceases fire after 8 minutes until boiling; filter; filtrate is dried in the air to during room temperature and is dropped into step (3) and (4) gains, and big fire decocts to boiling, ceases fire after stirring 2-4 minute with large ferrum spoon; leave standstill 9 hours, get supernatant loading air-tight bottle and namely obtain oral liquid medicine.
embodiment 3treat a Chinese medicine composition for varicose veins of the lower extremity, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Radix Angelicae Sinensis 13 parts, Rhizoma Dioscoreae Nipponicae 14 parts, Squama Manis 8 parts, Concha Ostreae 18 parts, 4 parts, Flos Carthami, Rhizoma Corydalis 16 parts, Herba speranskiae tuberculatae 23 parts, 25 parts, Radix Notoginseng, Radix Achyranthis Bidentatae 15 parts, Radix et Rhizoma Dysosmatis 7 parts, Rhizoma Chuanxiong 11 parts, Herba Lycopodii serrati 6 parts of Cacumen Securinegae Suffruticosaes 18 parts, Rhizoma Paridis 16 parts.
The preparation method of above-mentioned Chinese medicine composition, step is:
(1) Radix Angelicae Sinensis, Radix Notoginseng, Herba Lycopodii serrati and Rhizoma Chuanxiong are eluriated 3 times, be placed in shady and cool ventilation place to ventilate 13 hours, pressure cooker is put in chopping, a longer leather hose having certain degree of hardness is connected in gas outlet, then section leather hose of is wherein immersed in cold water and cool, another section of leather hose connects a carafe, is then separated the oil on upper strata, and the oil separated is exactly Mixed chaotic sequences;
(2) Flos Carthami and Rhizoma Paridis are cleaned the spray of chopping yellow wine even, sealing and standing 2 days, extrudes yellow wine and obtains processed with wine Flos Carthami and Rhizoma Paridis;
(3) Concha Ostreae is placed in boiled hot water, boils 1 minute, taking-up is dried in the air cool, is taken out by Carnis ostreae, is cut into block, is placed in parch 3-7 minute in pot, grinds into powder stand-by;
(4) cleaned by Squama Manis, steep 5 hours with rice vinegar, it is crisp to be placed in forging on smokeless stove fire, and grinding into smalls into powder, to cross 90 mesh sieves stand-by;
(5) Rhizoma Dioscoreae Nipponicae, Rhizoma Corydalis, Herba speranskiae tuberculatae, Radix Achyranthis Bidentatae, Radix et Rhizoma Dysosmatis and Cacumen Securinegae Suffruticosae are placed in marmite the water adding raw material gross weight 4.5 times; intense fire is fried open; turn slow fire boiling and add processed with wine Flos Carthami and Rhizoma Paridis after 13 minutes, big fire is heated to boiling, ceases fire after 4 minutes until boiling; filter; filtrate is dried in the air to during room temperature and is dropped into step (3) and (4) gains, and big fire decocts to boiling, ceases fire after stirring 2 minutes with large ferrum spoon; leave standstill 7.5 hours, get supernatant loading air-tight bottle and namely obtain oral liquid medicine.
embodiment 4treat a Chinese medicine composition for varicose veins of the lower extremity, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Radix Angelicae Sinensis 18 parts, Rhizoma Dioscoreae Nipponicae 20 parts, Squama Manis 13 parts, Concha Ostreae 23 parts, 6 parts, Flos Carthami, Rhizoma Corydalis 20 parts, Herba speranskiae tuberculatae 28 parts, 35 parts, Radix Notoginseng, Radix Achyranthis Bidentatae 25 parts, Radix et Rhizoma Dysosmatis 10 parts, Rhizoma Chuanxiong 14 parts, Herba Lycopodii serrati 8 parts of Cacumen Securinegae Suffruticosaes 23 parts, Rhizoma Paridis 16-19 part.
The preparation method of above-mentioned Chinese medicine composition, step is:
(1) Radix Angelicae Sinensis, Radix Notoginseng, Herba Lycopodii serrati and Rhizoma Chuanxiong are eluriated 5 times, be placed in shady and cool ventilation place to ventilate 18 hours, pressure cooker is put in chopping, a longer leather hose having certain degree of hardness is connected in gas outlet, then section leather hose of is wherein immersed in cold water and cool, another section of leather hose connects a carafe, is then separated the oil on upper strata, and the oil separated is exactly Mixed chaotic sequences;
(2) Flos Carthami and Rhizoma Paridis are cleaned the spray of chopping yellow wine even, sealing and standing 4 days, extrudes yellow wine and obtains processed with wine Flos Carthami and Rhizoma Paridis;
(3) Concha Ostreae is placed in boiled hot water, boils 3 minutes, taking-up is dried in the air cool, is taken out by Carnis ostreae, is cut into block, is placed in parch 3-7 minute in pot, grinds into powder stand-by;
(4) cleaned by Squama Manis, steep 7 hours with rice vinegar, it is crisp to be placed in forging on smokeless stove fire, and grinding into smalls into powder, to cross 110 mesh sieves stand-by;
(5) Rhizoma Dioscoreae Nipponicae, Rhizoma Corydalis, Herba speranskiae tuberculatae, Radix Achyranthis Bidentatae, Radix et Rhizoma Dysosmatis and Cacumen Securinegae Suffruticosae are placed in marmite the water adding raw material gross weight 5.5 times; intense fire is fried open; turn slow fire boiling and add processed with wine Flos Carthami and Rhizoma Paridis after 18 minutes, big fire is heated to boiling, ceases fire after 6 minutes until boiling; filter; filtrate is dried in the air to during room temperature and is dropped into step (3) and (4) gains, and big fire decocts to boiling, ceases fire after stirring 4 minutes with large ferrum spoon; leave standstill 8.5 hours, get supernatant loading air-tight bottle and namely obtain oral liquid medicine.
model case twoopen XX, female, 38 years old, Zhengzhou, henan people, heavy, the sour swollen discomfort of conscious left lower extremity before 5 years also accompanies edema, occurs the tortuous increasing of left lower extremity superficial vein slightly in Lumbricus shape simultaneously.What did not feel at that time sick, the thick symptom of the swollen discomfort of left lower extremity acid afterwards, tortuous increasing is day by day obvious, even all become difficult on foot, makes a move and all thinks that leg is sour endlessly swollen.
Take embodiment 4 gained Chinese medicine oral liquid and massage 10 days with the use of volatile oil, lump obviously reduces, and within 20 days, patient oneself sensation whole body has strength, from sweet recovery from illness, takes again present composition nothing recurrence in 10 days after recovery from illness.
embodiment 5treat a Chinese medicine composition for varicose veins of the lower extremity, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Radix Angelicae Sinensis 15 parts, Rhizoma Dioscoreae Nipponicae 17 parts, Squama Manis 10 parts, Concha Ostreae 20 parts, 5 parts, Flos Carthami, Rhizoma Corydalis 18 parts, Herba speranskiae tuberculatae 25 parts, 30 parts, Radix Notoginseng, Radix Achyranthis Bidentatae 20 parts, Radix et Rhizoma Dysosmatis 9 parts, Rhizoma Chuanxiong 13 parts, Herba Lycopodii serrati 7 parts of Cacumen Securinegae Suffruticosaes 20 parts, Rhizoma Paridis 17 parts.
The preparation method of above-mentioned Chinese medicine composition, step is:
(1) Radix Angelicae Sinensis, Radix Notoginseng, Herba Lycopodii serrati and Rhizoma Chuanxiong are eluriated 4 times, be placed in shady and cool ventilation place to ventilate 15 hours, pressure cooker is put in chopping, a longer leather hose having certain degree of hardness is connected in gas outlet, then section leather hose of is wherein immersed in cold water and cool, another section of leather hose connects a carafe, is then separated the oil on upper strata, and the oil separated is exactly Mixed chaotic sequences;
(2) Flos Carthami and Rhizoma Paridis are cleaned the spray of chopping yellow wine even, sealing and standing 3 days, extrudes yellow wine and obtains processed with wine Flos Carthami and Rhizoma Paridis;
(3) Concha Ostreae is placed in boiled hot water, boils 2 minutes, taking-up is dried in the air cool, is taken out by Carnis ostreae, is cut into block, is placed in parch 3-7 minute in pot, grinds into powder stand-by;
(4) cleaned by Squama Manis, steep 6 hours with rice vinegar, it is crisp to be placed in forging on smokeless stove fire, and grinding into smalls into powder, to cross 100 mesh sieves stand-by;
(5) Rhizoma Dioscoreae Nipponicae, Rhizoma Corydalis, Herba speranskiae tuberculatae, Radix Achyranthis Bidentatae, Radix et Rhizoma Dysosmatis and Cacumen Securinegae Suffruticosae are placed in marmite the water adding raw material gross weight 5 times; intense fire is fried open; turn slow fire boiling and add processed with wine Flos Carthami and Rhizoma Paridis after 15 minutes, big fire is heated to boiling, ceases fire after 5 minutes until boiling; filter; filtrate is dried in the air to during room temperature and is dropped into step (3) and (4) gains, and big fire decocts to boiling, ceases fire after stirring 3 minutes with large ferrum spoon; leave standstill 8 hours, get supernatant loading air-tight bottle and namely obtain oral liquid medicine.
experimental exampleobject is to verify whether this Chinese medicine composition has curative effect to treatment varicose veins of the lower extremity." new Chinese medicine guideline of clinical investigations " according to Ministry of Public Health formulation in 1993 is diagnosis basis, and totally 400 routine varicose veins of the lower extremity patients, the mean age is 50 years old.Random division is administration group and matched group.
Before the experiments one day, record patient health, look over patient body symptom every day, guarantee administration group and matched group situation basically identical.Administration group uses this product embodiments 5 gained Chinese medicine composition every day, within 10 days, is a course for the treatment of.Check patient body situation every day, make a record.Result is as following table 1:
Table 1:
efficacy analysis:when administration group (Chinese medicine composition of the present invention) uses 15 days, most patient sensory symptoms obviously alleviates, obviously feel to take a favorable turn in affected part, patient's emotion takes a turn for the better, during medication 30 days, patient is almost recovered, drug withdrawal a period of time has no repeatedly, the state of an illness is better controlled, matched group take medicine after curative effect obvious.Chinese medicine composition instant effect of the present invention, can reach the object alleviating rapidly patient's misery, and relapse rate is low, is a kind of Chinese medicine composition for the treatment of varicose veins of the lower extremity safely and effectively.
Claims (10)
1. treat a Chinese medicine composition for varicose veins of the lower extremity, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Radix Angelicae Sinensis 10-20 part, Rhizoma Dioscoreae Nipponicae 10-25 part, Squama Manis 5-15 part, Concha Ostreae 15-25 part, Flos Carthami 3-8 part, Rhizoma Corydalis 12-24 part, Herba speranskiae tuberculatae 20-30 part, Radix Notoginseng 20-40 part, Radix Achyranthis Bidentatae 13-27 part, Radix et Rhizoma Dysosmatis 4-17 part, Rhizoma Chuanxiong 10-15 part, Herba Lycopodii serrati 4-10 part Cacumen Securinegae Suffruticosae 15-25 part, Rhizoma Paridis 15-20 part.
2. the Chinese medicine composition for the treatment of varicose veins of the lower extremity according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Radix Angelicae Sinensis 13-18 part, Rhizoma Dioscoreae Nipponicae 14-20 part, Squama Manis 8-13 part, Concha Ostreae 18-23 part, Flos Carthami 4-6 part, Rhizoma Corydalis 16-20 part, Herba speranskiae tuberculatae 23-28 part, Radix Notoginseng 25-35 part, Radix Achyranthis Bidentatae 15-25 part, Radix et Rhizoma Dysosmatis 7-10 part, Rhizoma Chuanxiong 11-14 part, Herba Lycopodii serrati 6-8 part Cacumen Securinegae Suffruticosae 18-23 part, Rhizoma Paridis 16-19 part.
3. the Chinese medicine composition for the treatment of varicose veins of the lower extremity according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Radix Angelicae Sinensis 15 parts, Rhizoma Dioscoreae Nipponicae 17 parts, Squama Manis 10 parts, Concha Ostreae 20 parts, 5 parts, Flos Carthami, Rhizoma Corydalis 18 parts, Herba speranskiae tuberculatae 25 parts, 30 parts, Radix Notoginseng, Radix Achyranthis Bidentatae 20 parts, Radix et Rhizoma Dysosmatis 9 parts, Rhizoma Chuanxiong 13 parts, Herba Lycopodii serrati 7 parts of Cacumen Securinegae Suffruticosaes 20 parts, Rhizoma Paridis 17 parts.
4. the preparation method of the Chinese medicine composition of the treatment varicose veins of the lower extremity according to any one of claim 1-3, is characterized in that: step is as follows:
(1) Radix Angelicae Sinensis, Radix Notoginseng, Herba Lycopodii serrati and Rhizoma Chuanxiong are eluriated 2-6 time, be placed in shady and cool ventilation place ventilation 10-20 hour, pressure cooker is put in chopping, a longer leather hose having certain degree of hardness is connected in gas outlet, then section leather hose of is wherein immersed in cold water and cool, another section of leather hose connects a carafe, is then separated the oil on upper strata, and the oil separated is exactly Mixed chaotic sequences;
(2) Flos Carthami and Rhizoma Paridis are cleaned the spray of chopping yellow wine even, sealing and standing 2-4 days, extrudes yellow wine and obtains processed with wine Flos Carthami and Rhizoma Paridis;
(3) Concha Ostreae is placed in boiled hot water, boils 1-3 minute, taking-up is dried in the air cool, is taken out by Carnis ostreae, is cut into block, is placed in parch 3-7 minute in pot, grinds into powder stand-by;
(4) cleaned by Squama Manis, with rice vinegar bubble 4-8 hour, it is crisp to be placed in forging on smokeless stove fire, and grinding into smalls into powder, to cross 80-120 mesh sieve stand-by;
(5) Rhizoma Dioscoreae Nipponicae, Rhizoma Corydalis, Herba speranskiae tuberculatae, Radix Achyranthis Bidentatae, Radix et Rhizoma Dysosmatis and Cacumen Securinegae Suffruticosae are placed in marmite the water adding raw material gross weight 4-6 times; intense fire is fried open; add processed with wine Flos Carthami and Rhizoma Paridis after turning slow fire boiling 10-20 minute, big fire is heated to boiling, ceases fire after 2-8 minute until boiling; filter; filtrate is dried in the air to during room temperature and is dropped into step (3) and (4) gains, and big fire decocts to boiling, ceases fire after stirring 2-4 minute with large ferrum spoon; leave standstill 7-9 hour, get supernatant loading air-tight bottle and namely obtain oral liquid medicine.
5. preparation method according to claim 4, is characterized in that: Radix Angelicae Sinensis, Radix Notoginseng, Herba Lycopodii serrati and Rhizoma Chuanxiong are eluriated 3-5 all over (preferred, Radix Angelicae Sinensis, Radix Notoginseng, Herba Lycopodii serrati and Rhizoma Chuanxiong are eluriated 4 times) by step (1).
6. preparation method according to claim 4, is characterized in that: step (1) is placed in the ventilation of shady and cool ventilation place 13-18 hour (preferred, to be placed in shady and cool ventilation place and to ventilate 15 hours).
7. preparation method according to claim 4, is characterized in that: Carnis ostreae takes out by step (3), is cut into block, to be placed in pot parch 4-6 minute (preferred, to be taken out by Carnis ostreae, be cut into block, to be placed in pot parch 5 minutes).
8. preparation method according to claim 4, is characterized in that: Squama Manis is cleaned by step (4), with rice vinegar bubble 5-7 hour (preferred, to be cleaned by Squama Manis, steep 6 hours with rice vinegar).
9. preparation method according to claim 4, it is characterized in that: Rhizoma Dioscoreae Nipponicae, Rhizoma Corydalis, Herba speranskiae tuberculatae, Radix Achyranthis Bidentatae, Radix et Rhizoma Dysosmatis and Cacumen Securinegae Suffruticosae are placed in marmite and add raw material gross weight 4.5-5.5 water doubly (preferred, Rhizoma Dioscoreae Nipponicae, Rhizoma Corydalis, Herba speranskiae tuberculatae, Radix Achyranthis Bidentatae, Radix et Rhizoma Dysosmatis and Cacumen Securinegae Suffruticosae to be placed in marmite the water adding raw material gross weight 5 times) by step (5).
10. preparation method according to claim 4, is characterized in that: step (5) adds processed with wine Flos Carthami and Rhizoma Paridis (preferred, to turn slow fire boiling and add processed with wine Flos Carthami and Rhizoma Paridis after 15 minutes) after turning slow fire boiling 13-18 minute.
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