CN105250525A - Traditional Chinese medicine lotion for treating diabetic foot and preparation method thereof - Google Patents
Traditional Chinese medicine lotion for treating diabetic foot and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine lotion for treating a diabetic foot. The traditional Chinese medicine lotion for treating the diabetic foot is mainly prepared from, by weight, 1-5 parts of blackend swallowwort roots, 20-35 parts of ormosia, 1-5 parts of saffron crocus, 25-40 parts of rhodiola rosea, 25-35 parts of indigo naturalis, 5-12 parts of radices trichosanthis, 9-30 parts of pearl powder, 2-9 parts of rose hip seed oil, 5-15 parts of honeysuckles, 25-35 parts of golden larch bark, 5-9 parts of burdock, 9-30 parts of calamine, 5-15 parts of ailanthus altissima bark (the preferable proportion of the ailanthus altissima bark is 5.5-14.5 parts) and 3-6 parts of tortoise plastron. According to the traditional Chinese medicine lotion for treating the diabetic foot, blackend swallowwort roots, saffron crocus, ormosia, golden larch bark and the like have the effects of clearing heat, removing toxicity, killing bacteria and promoting tissue regeneration, and the pain brought by the diabetic foot can be effectively improved.
Description
Technical field
The invention discloses a kind of Chinese medicine lotion, especially Chinese medicine lotion for the treatment of diabetic foot and preparation method thereof, belong to traditional Chinese medicine field.
Background technology
Foot is the target organ that of this multisystem disease of diabetes is complicated.Diabetics merges too high mechanical pressure because of peripheral neuropathy and peripheral blood vessel, destruction and the teratogenesis of foot soft tissue and osteoarticular system can be caused, and then cause a series of foot problems, from slight nervous symptoms to serious ulcer, infection, angiopathy, Charcot arthrosis and Neuropathic fracture.If active treatment fully can not solve symptom and the complication of lower limb appearance, then can cause catastrophic consequence.Therefore, carry out in diabetics and will have important meaning to the early prevention of foot problems and treatment.
The cause of disease: 1. ulcer: a lot of foot complication of diabetics rise from sensualness neuropathy and slight autonomous and nervus motorius pathological changes.Wherein sensory nerve pathological changes merges too high mechanical stress, is the main initiating agent causing foot ulcers and infection.Inflammation and histologic lesion are the results that alternate stress to a certain degree acts on the region that specifically loses sensibility.Cause ulcer from the pressure of ground, shoes or other contiguous toes or shearing force, owing to lacking normal Neuroprotective Mechanisms, ulcer often increases the weight of because of the existence of apophysis.Autonomic pathological changes causes the normal perspire regulatory function of skin, skin temperature regulatory function and blood to transport regulating power forfeiture, causes local organization pliability to reduce, and forms thick callus and easier broken and cracking.In addition, the forfeiture of normal perspire ability has blocked the rehydration of local organization, causes tissue to destroy further, makes deep tissue be easier to bacteria planting.Nervus motorius pathological changes also serves certain effect in the morbidity of diabetic foot, and the contracture of the inherent flesh of foot causes typical claw toe deformity.The hyperextension of metatarsophalangeal joints is also proved to be able to directly increase head of metatarsal bone downforce, makes this position more easily form ulcer.Nearly interphalangeal joint flexing causes the ulcerated risk of the interphalangeal joint dorsal part of projection and toe point sole of the foot side to increase, and vascular lesion makes the tissue destroyed be difficult to healing.2. infect: dysautonomia causes skin soft tissue to destroy, and causes outer derived bacterium to invade.Chemotaxis change causes leukocytoreaction inefficiency.In addition, hyperglycemia, partial pressure of oxygen reduction and malnutrition etc. can cause tissue edema jointly, acid is gathered, height blends poor efficiency anaerobic metabolism.This type of environment is applicable to bacterial growth, and hinders leukocytic function.In addition, it is limited that angiopathy can cause antibiotic to transport, and causes antibacterial elimination efficiency to reduce further, cause local soft tissue to infect, even myelitic formation.3.Charcot arthrosis: be the destructive pathological changes of gradual weight-bearing joints.Traumatic nerve injury theory is thought, loses the pain sensation and somesthetic sensibility back foot part suffers mechanical damage repeatedly or the wound of single-shot can cause Charcot arthropathy; Neural blood vessel theory is thought, the lesion region blood that autonomic nervous dysfunction causes causes bone absorption and strength reduction for increase, and then wound repeatedly causes osteoclasia with unstable.4. toes deformity: nervus motorius pathological changes causes the contracture of the inherent flesh of foot, causes typical claw toe deformity.
Clinical manifestation: the diverse clinical manifestations of diabetic foot.1. early stage: sensation changes the performance in ankle socks sample usually, first involves far-end of limb, then proximally develops.Light touch, somesthetic sensibility, jointly the weakening of thermo aesthesia and pain perception; Nervus motorius pathological changes shows as the inherent amyotrophy of foot, occurs claw toe deformity; Autonomic nerve is got involved and is shown as the normal perspire of skin, temperature and the forfeiture of blood fortune regulatory function, causes local organization pliability to reduce, forms thick callus and easier broken and cracking.2. the later stage: outside the symptom that the above-mentioned early stage neuropathy that continues causes, also can occur ulcer, infection, osteomyelitis, Charcot arthrosis etc.
In the patent of existing treatment diabetic foot, Authorization Notice No. CN103656372B(application number 201310459029.1) disclose a kind of diabetic foot ointment, it is characterized in that it is made up of the raw material of following weight: Radix Notoginseng 40-45g, Rhizoma Coptidis
55-60g, Rhizoma Paridis 35-40g, Pseudobulbus Bletillae (Rhizoma Bletillae) 50-55g, Radix Ampelopsis 45-50g, Radix Cynanchi Atrati 50-55g, Radix Et Rhizoma Rhei 45-50g, Herba Centellae 50-55g, Rhizoma Smilacis Chinensis 40-45g, Radix Rhapontici 35-40g, Cortex Phellodendri 45-50g, Semen Phaseoli 50-55g, Radix Scutellariae 55-60g, Rhizoma Corydalis 45-50g, Fructus Gardeniae 40-45g, Herba Cissampelotis 45-50g, Fructus Forsythiae 35-40g, Rabdosia rubescens 35-40g, Herba Glechomae 30-35g, Rhizoma Polygoni Cuspidati 45-50g, Fructus Arctii 40-45g, Radix Rhodiolae 45-50g, Borneolum Syntheticum 25-30g, Radix Glycyrrhizae 45-50g, Radix Berberidis 40-45g, Ilex purpurea Hassk.[I.chinensis Sims 45-50g, Herba Senecionis Scandentis 45-50g, Herba Lobeliae Chinensis 45-50g, Herba Scutellariae Barbatae 45-50g, Rhizoma Et Radix Baphicacanthis Cusiae 45-50g, Herba Lysimachiae 40-45g, Herba Houttuyniae 40-45g, Herba Andrographis 45-50g, Folium Ginkgo 50-55g, Herba Taraxaci 35-40g, Radix Angelicae Sinensis 45-50g, Radix Picriae felterrae 45-50g, Cera Flava 1200g, non-transgenic salad oil 10 kilograms.Authorization Notice No. CN102940677B(application number 201210428581.X) disclose a kind of medicine Chinese medicine lotion for the treatment of diabetic foot, it is characterized in that: it is the medicament that medicinal raw material is made by Radix Rhodiolae, eupolyphaga, Aspongopus and Radix Glycyrrhizae; The weight of described crude drug is Radix Rhodiolae 12 parts, eupolyphaga 6 parts, Aspongopus 3 parts, 2 parts, Radix Glycyrrhizae; The preparation method of described medicine Chinese medicine lotion adds suitable quantity of water respectively for getting crude drug, adopts decocting method to extract 2 times respectively, filters, merge 2 filtrates, by each concentrated solution mix homogeneously after concentrated, dry, is distributed into bag after granulation.
Now, Chinese medicine occupies very important status on treatment diabetic foot, but is inconvenient to carry, and uncertain therapeutic efficacy is cut, and therapeutic effect has much room for improvement.
Summary of the invention
For existing current treatment status, an object of the present invention is to provide a kind of Chinese medicine lotion for the treatment of diabetic foot, by heat-clearing and toxic substances removing, relieving itching and eliminating swelling, granulation promoting, the Chinese medicine composition holding up this training first, there is feature easy to operate, evident in efficacy, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned Chinese medicine lotion.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat a Chinese medicine lotion for diabetic foot, take off the primary raw material stating weight proportion and be prepared from: Radix Cynanchi Atrati 1-5 part, Semen Phaseoli 20-35 part, Stigma Croci 1-5 part, Radix Rhodiolae 25-40 part, Indigo Naturalis 25-35 part, Radix Trichosanthis 5-12 part, Margarita powder 9-30 part, Rosehips oil 2-9 part, Flos Lonicerae 5-15 part, Cortex Pseudolaricis 25-35 part, Fructus Arctii 5-9 part, Calamina 9-30 part, ailanthus altissima (mill.) swingle skin 5-15 part (preferred proportioning, ailanthus altissima (mill.) swingle skin 5.5-14.5 part), Carapax et Plastrum Testudinis 3-6 part.
Treat a Chinese medicine lotion for diabetic foot, preferred scheme, take off the primary raw material stating weight proportion and be prepared from: Radix Cynanchi Atrati 2-4 part, Semen Phaseoli 25-30 part, Stigma Croci 2-4 part, Radix Rhodiolae 30-35 part, Indigo Naturalis 28-32 part, Radix Trichosanthis 7-10 part, Margarita powder 15-25 part, Rosehips oil 3-7 part, Flos Lonicerae 8-12 part, Cortex Pseudolaricis 28-32 part, Fructus Arctii 6-8 part, Calamina 15-25 part, ailanthus altissima (mill.) swingle skin 8-12 part, Carapax et Plastrum Testudinis 4-5 part.
Treat a Chinese medicine lotion for diabetic foot, better preferred scheme, take off the primary raw material stating weight proportion and be prepared from: Radix Cynanchi Atrati 3 parts, 28 parts, Semen Phaseoli, Stigma Croci 3 parts, Radix Rhodiolae 32 parts, Indigo Naturalis 30 parts, Radix Trichosanthis 8 parts, Margarita powder 20 parts, Rosehips oil 6 parts, Flos Lonicerae 10 parts, Cortex Pseudolaricis 30 parts, Fructus Arctii 7 parts, Calamina 20 parts, ailanthus altissima (mill.) swingle skin 10 parts, Carapax et Plastrum Testudinis 4.5 parts.
Treat a preparation method for the Chinese medicine lotion of diabetic foot, preparation process is as follows:
1. be placed in marmite by Semen Phaseoli, add Semen Phaseoli weight 10-20 warm water doubly, soak 4-6 hour, little fire puts into appropriate cold water after simmering 50-70 minute slowly, then boils 10-20 minute, and filter, filtrate is stand-by, and filtering residue pulverizes slagging dries stand-by;
2. by step 1. gained disintegrating slag and Indigo Naturalis, Radix Trichosanthis, Margarita powder, Rosehips oil mixes, be placed in plate with preservative film parcel place 40-60 minute stand-by;
3. Radix Cynanchi Atrati, Stigma Croci, Radix Rhodiolae, Flos Lonicerae, Cortex Pseudolaricis, Fructus Arctii and ailanthus altissima (mill.) swingle skin are placed in the hot pot dryouied, fry 5-15 minute, dry in the air to crisp, grind stand-by;
4. Calamina and Carapax et Plastrum Testudinis are placed in step 1. gained filtrate, soak 20-40 minute, forging is crisp, grinds 40-80 mesh sieve stand-by;
5. by step 2.-4. gains mixing, be placed in fine and close gauze, closing in tighten, adds vinegar, and intense fire is fried open, and turns 10-20 minute at a simmer, leaches medicinal liquid and bottle and get final product.
The preparation method of above-mentioned Chinese medicine lotion, 1. step adds Semen Phaseoli weight 13-18 warm water doubly, and soak 4.5-5.5 hour, little fire is put into appropriate cold water and (preferably added the warm water of Semen Phaseoli weight 15 times after simmering 55-65 minute slowly, soak 5 hours, little fire puts into appropriate cold water after simmering 60 minutes slowly).
The preparation method of above-mentioned Chinese medicine lotion, 1. step boils 13-18 minute again, filters, filtrate stand-by (preferably boil 15 minutes again, filter, filtrate is stand-by).
The preparation method of above-mentioned Chinese medicine lotion, 2. step is placed in plate and places 45-55 minute stand-by (being preferably placed in plate stand-by with preservative film parcel placement 50 minutes) with preservative film parcel.
The preparation method of above-mentioned Chinese medicine lotion, 3. Radix Cynanchi Atrati, Stigma Croci, Radix Rhodiolae, Flos Lonicerae, Cortex Pseudolaricis, Fructus Arctii and ailanthus altissima (mill.) swingle skin are placed in the hot pot dryouied by step, fry 8-13 minute (preferably, Radix Cynanchi Atrati, Stigma Croci, Radix Rhodiolae, Flos Lonicerae, Cortex Pseudolaricis, Fructus Arctii and ailanthus altissima (mill.) swingle skin are placed in the hot pot dryouied, fry 10 minutes).
The preparation method of above-mentioned Chinese medicine lotion, 4. step soaks 25-35 minute, and forging is crisp, grinds 50-70 mesh sieve stand-by (preferred, soak 30 minutes, forging is crisp, grinds 60 mesh sieves stand-by).
The preparation method of above-mentioned Chinese medicine lotion, step 5. intense fire is fried open, and turns 13-18 at a simmer minute (preferred, intense fire is fried open, and turns 15 minutes at a simmer).
Using method: be the therapeutic effect making the present invention reach best, gained Chinese medicine lotion drips in warm water, foot bath 20 minutes before sleep in evening every day, drip 20ml, 5 days be a course for the treatment of at every turn.
The pharmacological effect of each crude drug is respectively:
Radix Cynanchi Atrati: Radix Cynanchi Atrati, another name: common vetch grass, know that micro-old, old melon gourd dipper root, mountain cigarette root, hundred swing grass, Baima common vetch, Rhizoma Cynanchi Stauntonii, Radix Tylophorae arenicolae, root and part rhizome hyoscine, have except fidgets due to deficiency, heat clearing away are loose swollen, the effect of granulation promoting pain relieving, fidgets due to deficiency vomiting after can managing property, dribbling urination, nephritis, urinary tract infection, edema, bronchitis and rheumatic lumbago and scelalgia etc.
Semen Phaseoli: heat-clearing and toxic substances removing, invigorating spleen and reinforcing stomach, inducing diuresis to remove edema, ventilation relieving restlessness etc., can treat the diseases such as dysuria, edema due to deficiency of the spleen, beriberi.Disappear pyretic toxicity carbuncle, dispelling malignant blood, not to the utmost, stuffy sensation with restlessness.To harness the river swollen musculus cutaneus distension; Smash on scumbling carbuncle; Main children's's acute jaundice, rotten skin ulcer, extracting juice order washes it; Cuisines can be made us; End and Ovum Gallus domesticus album are adjusted and are coated with pyretic toxicity carbuncle; Ventilation, strengthening the spleen and stomach.
Stigma Croci: Stigma Croci has thin channels and activating collaterals, stimulating the menstrual flow silt, scattered silt relieving accumulation of pathogens, reducing swelling and alleviating pain, removing pathogenic heat from blood and toxic substance from the body, troubled thoughts pent-up, adheres to for a long time taking receiving and makes us heart happiness, improve effect of the immunity of human body comprehensively.Modern pharmacological research proves that it is to improving the aspect determined curative effects such as blood supply of cardiac muscle oxygen supply, and Stigma Croci contains the composition of multiple glycoside, and multiple glycoside obviously can increase large blood flow coronarius.
Radix Rhodiolae: nature and flavor: cold, sweet, puckery.Gui Jing: lung meridian.Function cures mainly: have QI invigorating lung heat clearing, Fructus Alpiniae Oxyphyllae is nourished heart, effect of hemostasis with astringents, dissipating blood stasis for subsidence of swelling.Cure mainly deficiency of vital energy and physically weak, after being ill fear of cold, shortness of breath and fatigue, cough due to lung-heat, spitting of blood, leucorrhea diarrhoea, traumatic injury etc.
Indigo Naturalis: have another name called Concha Meretricis Seu Cyclinae powder, indigo-blue flower, for the leaf of Acanthaceae Acanthaceous indigo platymiscium Acanthaceous indigo, Polygonaceae arsesmart polygonum tinctorium ait., pulse family anil Folium et Caulis Indigoferae Tinctoriae, Cruciferae Isatis indigotica Fort. platymiscium Isatis indigotica Fort. or stem and leaf are through processing obtained dried powder or agglomerate.The property of medicine: this product is navy blue powder, body is light, and easily fly upward, micro-have careless stink smell, salty in the mouth, cold in nature.Composition: its main component has indirubin, indigo.Find according to modern pharmacological research, this medical instrument has effect of antitumor, anti-inflammatory and antalgic, antiulcer, antibacterial, clearing away heat and cooling blood, removing toxic substances, and for the malicious macule of temperature, laryngopharynx swelling and pain, spits blood, epistaxis, the symptoms such as spitting of blood.
Radix Trichosanthis: Radix Trichosanthis, Chinese medicine name." book on Chinese herbal medicine justice ": medicine so-called Radix Trichosanthis person wantonly, namely cuts into slices with it with the root that withers, has the name of powder, real without powder.Radix Trichosanthis is the root of cucurbitaceous plant Chinese juniper beach wormwood, is a kind of Chinese medicine, and be clearing away heat-fire class medicine, its concrete effect is clearing away heat-fire, promoting the production of body fluid to quench thirst, and evacuation of pus is subsided a swelling.Cure mainly: control calentura thirsty, quench one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle, hemorrhoid flaccidity.For treatment diabetes, conventional it and drugs for nourishing yin with the use of, to reach the effect for the treatment of both the principal and secondary aspects of a disease.
Margarita powder: enhancing immunity, supplement calcium, Bao Chunyan decline, improving water flood, treatment ulcer, nourishing the liver to improve visual acuity, secondary buck.Free radical is old and feeble important priming factors, and with advancing age, metabolism slows down gradually, and therefore the ability of self opposing free radical can reduce, and skin and organ just there will be phenomenon aging ahead of time.Three kinds of trace element such as the manganese that Margarita powder itself contains, copper, zinc are the compositions of composition SOD, are coated with face, can promote the activity of human skin superoxide dismutase (SOD), the synthesis of check melanin with Margarita powder, keep whitening skin.
Rosehips oil: enhanced tissue effect, produces active function of organization, easily permeates skin corium, moisturizing, promotes effect of the smooth whitening of skin.To cell regeneration, maintenance and healing have splendid effect.It can make skin pigment desalinate, and reappears homogeneous hue, makes skin level and smooth.It can keep skin clean, soft, soft, moistening, deflation, solid, the effect of high resilience, Feng Li.Especially more effect is shown in general coarse skin.
Flos Lonicerae: Flos Lonicerae is just extensive and famous with its medical value since ancient times.Its effect mainly heat-clearing and toxic substances removing, cures mainly epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle furunculosis etc.Modern study proves, Flos Lonicerae contains the pharmacological component such as chlorogenic acid, luteolin glycosides, stronger restraint is had to the various pathogens such as Hemolytic streptococcus, staphylococcus aureus and upper respiratory tract infection Causative virus etc., in addition also can enhancing immunity, antiearly pregnancy, hepatoprotective, antitumor, antiinflammatory, antipyretic, hemostasis (blood coagulation), suppress intestinal absorption cholesterol etc., its clinical application widely, can be used for the treatment of respiratory tract infection, bacillary dysentery, acute urinary, hypertension etc. more than 40 with other medicines compatibility and plant disease.
Cortex Pseudolaricis: have another name called arhat Cortex Pini Massonianae, wattle skin, pseudolaricis,cortex is root bark and the near root bark of Pinaceae Pseudolarix plant golden larch.The property of medicine: root bark is irregular strip, distortion and slightly rolling up, not of uniform size, matter is tough, feeble QI, acrid in the mouth, hardship, warm in nature.Composition: root bark contains pseudolaric acid B, betulic acid, myricetin, amaron alcohol A and B etc.Find according to modern pharmacological research, this medical instrument has effect of antifungal, anticancer, expelling wind and removing dampness, killing parasites for relieving itching, for eczema, and neurodermatitis.
Fructus Arctii: there is dispelling wind and heat pathogens, lung qi dispersing rash, sore-throat relieving eliminating stagnation, effect of removing toxic substances and promoting subsidence of swelling.Belong to wind-heat-dispersing medicinal in diaphoretic medicine.Modern study, Fructus Arctii also can be used for preventing and treating diabetic nephropathy; The arctigenin that Arctium lappa fruit generates through hydrolysis containing arctigenin has active anticancer.
Calamina: be carbonate calcite race's minerals smithsonite or carbonate mineral marionite.Composition: 1. Calamina is mainly old is zinc carbonate, still containing small amounts calcium 0.27%, magnesium oxide 0.45%, ferrum oxide 0.58%, manganese oxide 0.01%.Wherein zinc is often by a small amount of ferrum (bivalence) is replaced.What have still contains a small amount of cobalt, copper, cadmium, lead etc.2. Calamina main component of swimming is basic zinc carbonate, and leaded, the magazine such as cadmium, magnesium, ferrum, aluminum.The property of medicine: sweet, flat.Return liver, spleen, lung meridian.Function cures mainly: improving eyesight removing nebula, and removing dampness is antipruritic, expelling pus and promoting granulation.Cure mainly conjunctival congestion and swelling pain, marginal blepharitis eye, many tear photophobia, nebula film bulbar conjunctiva polyp, ulcer being unable to heal, skin eczema, pudendum pruritus due to damp pathogen.
Ailanthus altissima (mill.) swingle skin: other application ailanthus altissima (mill.) swingle barks of ailanthus altissima (mill.) swingle, root bark, fruit all can be used as medicine, and have effect of heat clearing and damp drying, astringent therapy leukorrhagia stopping, antidiarrheal, hemostasis.Chinese medicine document is recorded, and ailanthus altissima (mill.) swingle has " mild toxicity ", only for decocting soup washout.Ailanthus altissima (mill.) swingle leaf can not eat.
Carapax et Plastrum Testudinis: Carapax et Plastrum Testudinis contains several amino acids, protein, fat and calcium salt etc. containing bone gelatin, hydrolysate.Carapax et Plastrum Testudinis nourishing kidney YANG hyperactivity suppressing, replenishing kidney and strengthening bone, reinforcing the heart of nourishing blood.Cure mainly hyperactivity of YANG due to deficiency of YIN, yin asthenia generating intrinsic heat, stirring-up of pathogenic wind in the interior resulting from deficiency.To suffer from a deficiency of the kidney the atrophic debility of bones, infantile metopism.Deficiency of YIN-blood, palpitation with fear, insomnia, forgetful.Carapax et Plastrum Testudinis is sternite and the carapace of Testudinidae animal.
Compared with prior art, technical advantage of the present invention is embodied in:
1, the present invention's medical material used does not have toxicity, and the health mechanism for sufferer can not cause damage, and audient crowd is wide, and applicable female patient is taken.
2, bright the used medical material relative inexpensiveness of this law, compared with prior art the bright obtained Chinese medicine lotion cost of this law is cheaper.
3, therapeutic effect of the present invention is compared to prior art, and therapeutic effect is more obvious, and treatment cycle is short, does not have obvious sequela, can life-time service.
4, heat-clearing and toxic substances removing: the Radix Cynanchi Atrati in medicine, Stigma Croci, Semen Phaseoli, Cortex Pseudolaricis etc. have effect of heat-clearing and toxic substances removing, sterilizing, effectively can improve the slight illness that diabetic foot brings.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1: a kind of Chinese medicine lotion for the treatment of diabetic foot, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Radix Cynanchi Atrati 1 part, 20 parts, Semen Phaseoli, Stigma Croci 1 part, Radix Rhodiolae 25 parts, Indigo Naturalis 25 parts, Radix Trichosanthis 5 parts, Margarita powder 9 parts, Rosehips oil 2 parts, Flos Lonicerae 5 parts, Cortex Pseudolaricis 25 parts, Fructus Arctii 5 parts, Calamina 9 parts, ailanthus altissima (mill.) swingle skin 5 parts, Carapax et Plastrum Testudinis 3 parts.
The preparation method of the Chinese medicine lotion of above-mentioned treatment diabetic foot, step is as follows:
1. be placed in marmite by Semen Phaseoli, add the warm water of Semen Phaseoli weight 10 times, soak 4 hours, little fire puts into appropriate cold water after simmering 50 minutes slowly, then boils 10 minutes, and filter, filtrate is stand-by, and filtering residue pulverizes slagging dries stand-by;
2. by step 1. gained disintegrating slag and Indigo Naturalis, Radix Trichosanthis, Margarita powder, Rosehips oil mixes, and is placed in plate stand-by with preservative film parcel placement 40 minutes;
3. Radix Cynanchi Atrati, Stigma Croci, Radix Rhodiolae, Flos Lonicerae, Cortex Pseudolaricis, Fructus Arctii and ailanthus altissima (mill.) swingle skin are placed in the hot pot dryouied, fry 5 minutes, dry in the air to crisp, grind stand-by;
4. Calamina and Carapax et Plastrum Testudinis are placed in step 1. gained filtrate, soak 20 minutes, forging is crisp, grinds 40 mesh sieves stand-by;
5. by step 2.-4. gains mixing, be placed in fine and close gauze, closing in tighten, adds vinegar, and intense fire is fried open, and turns 10 minutes at a simmer, leaches medicinal liquid and bottle and get final product.
model case one:liu XX, man, 46 years old, Xuecheng District, Zaozhuang City of Shandong Province.Symptom: these more than 5 years of diabetes mellitus's history, diabetic foot 3 years, bilateral ulcer of foot, gangrene, go over many policlinics all fixed with amputation treatment of performing the operation, at this city hospital row right lower extremity high-level amputation, after amputation, wound surface infects once again, ulcer, the long-time disunion of wound surface, cannot carry out the operation of opposite side lower extremity amputation, belong to 4 grades by this sufferer of wagner classification, learn unintentionally Chinese medicine lotion of the present invention.
Use embodiment 1 gained Chinese medicine lotion, treat 10 days, the place of the right side ulcer wound surface redness after amputation disappears, continual cure 40 days again, ulcer wound surface all healed, the ulcer gangrene also all healed of amputation is treated in left side in advance, wound surface is smooth, and patient and family members are deeply grateful.
embodiment 2treat a Chinese medicine lotion for diabetic foot, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Radix Cynanchi Atrati 5 parts, 35 parts, Semen Phaseoli, Stigma Croci 5 parts, Radix Rhodiolae 40 parts, Indigo Naturalis 35 parts, Radix Trichosanthis 12 parts, Margarita powder 30 parts, Rosehips oil 9 parts, Flos Lonicerae 15 parts, Cortex Pseudolaricis 35 parts, Fructus Arctii 9 parts, Calamina 30 parts, ailanthus altissima (mill.) swingle skin 15 parts, Carapax et Plastrum Testudinis 6 parts.
The preparation method of the Chinese medicine lotion of above-mentioned treatment diabetic foot, step is as follows:
1. be placed in marmite by Semen Phaseoli, add the warm water of Semen Phaseoli weight 20 times, soak 6 hours, little fire puts into appropriate cold water after simmering 70 minutes slowly, then boils 20 minutes, and filter, filtrate is stand-by, and filtering residue pulverizes slagging dries stand-by;
2. by step 1. gained disintegrating slag and Indigo Naturalis, Radix Trichosanthis, Margarita powder, Rosehips oil mixes, and is placed in plate stand-by with preservative film parcel placement 60 minutes;
3. Radix Cynanchi Atrati, Stigma Croci, Radix Rhodiolae, Flos Lonicerae, Cortex Pseudolaricis, Fructus Arctii and ailanthus altissima (mill.) swingle skin are placed in the hot pot dryouied, fry 15 minutes, dry in the air to crisp, grind stand-by;
4. Calamina and Carapax et Plastrum Testudinis are placed in step 1. gained filtrate, soak 40 minutes, forging is crisp, grinds 80 mesh sieves stand-by;
5. by step 2.-4. gains mixing, be placed in fine and close gauze, closing in tighten, adds vinegar, and intense fire is fried open, and turns 20 minutes at a simmer, leaches medicinal liquid and bottle and get final product.
model case two:lee XX, female, 39 years old, Shenxian County, Liaocheng of Shandong Province.Symptom: patient is the workman in chemical plant, suffers from two paraplela inferior, diabetes 5 years, suffer from diabetic foot (right foot) ulcer gangrene 3 years, because ulcer and gangrene develop rapidly the complete depigmentation of right foot, right leg fibula depigmentation, only residual Bare tibia is outside, skin and flesh has not existed completely, bear because medical expense is unable, hospital surgical has certain difficulty, delays the state of an illness always and increases the weight of day by day, by the agency of is sought medical advice to burn hospital, belongs to 5 grades by this sufferer of wagner classification.
Use embodiment 2 gained Chinese medicine lotion, adhere to that medication is uninterrupted, through the Drug therapy of half a year, traumatic infection is suppressed, the continuous elongation growth of granulation tissue, and surface is covered by epidermis gradually, the tibia exposed the most at last wrap up by skin and flesh, patient's wound surface rehabilitates.
embodiment 3treat a Chinese medicine lotion for diabetic foot, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Radix Cynanchi Atrati 2 parts, 25 parts, Semen Phaseoli, Stigma Croci 2 parts, Radix Rhodiolae 30 parts, Indigo Naturalis 28 parts, Radix Trichosanthis 7 parts, Margarita powder 15 parts, Rosehips oil 3 parts, Flos Lonicerae 8 parts, Cortex Pseudolaricis 28 parts, Fructus Arctii 6 parts, Calamina 15 parts, ailanthus altissima (mill.) swingle skin 8 parts, Carapax et Plastrum Testudinis 4 parts.
The preparation method of the Chinese medicine lotion of above-mentioned treatment diabetic foot, step is as follows:
1. be placed in marmite by Semen Phaseoli, add the warm water of Semen Phaseoli weight 13 times, soak 4.5 hours, little fire puts into appropriate cold water after simmering 55 minutes slowly, then boils 13 minutes, and filter, filtrate is stand-by, and filtering residue pulverizes slagging dries stand-by;
2. by step 1. gained disintegrating slag and Indigo Naturalis, Radix Trichosanthis, Margarita powder, Rosehips oil mixes, and is placed in plate stand-by with preservative film parcel placement 45 minutes;
3. Radix Cynanchi Atrati, Stigma Croci, Radix Rhodiolae, Flos Lonicerae, Cortex Pseudolaricis, Fructus Arctii and ailanthus altissima (mill.) swingle skin are placed in the hot pot dryouied, fry 8 minutes, dry in the air to crisp, grind stand-by;
4. Calamina and Carapax et Plastrum Testudinis are placed in step 1. gained filtrate, soak 25 minutes, forging is crisp, grinds 50 mesh sieves stand-by;
5. by step 2.-4. gains mixing, be placed in fine and close gauze, closing in tighten, adds vinegar, and intense fire is fried open, and turns 13 minutes at a simmer, leaches medicinal liquid and bottle and get final product.
embodiment 4treat a Chinese medicine lotion for diabetic foot, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Radix Cynanchi Atrati 4 parts, 30 parts, Semen Phaseoli, Stigma Croci 4 parts, Radix Rhodiolae 35 parts, Indigo Naturalis 32 parts, Radix Trichosanthis 10 parts, Margarita powder 25 parts, Rosehips oil 7 parts, Flos Lonicerae 12 parts, Cortex Pseudolaricis 32 parts, Fructus Arctii 8 parts, Calamina 25 parts, ailanthus altissima (mill.) swingle skin 12 parts, Carapax et Plastrum Testudinis 5 parts.
The preparation method of the Chinese medicine lotion of above-mentioned treatment diabetic foot, step is as follows:
1. be placed in marmite by Semen Phaseoli, add the warm water of Semen Phaseoli weight 18 times, soak 5.5 hours, little fire puts into appropriate cold water after simmering 65 minutes slowly, then boils 18 minutes, and filter, filtrate is stand-by, and filtering residue pulverizes slagging dries stand-by;
2. by step 1. gained disintegrating slag and Indigo Naturalis, Radix Trichosanthis, Margarita powder, Rosehips oil mixes, and is placed in plate stand-by with preservative film parcel placement 55 minutes;
3. Radix Cynanchi Atrati, Stigma Croci, Radix Rhodiolae, Flos Lonicerae, Cortex Pseudolaricis, Fructus Arctii and ailanthus altissima (mill.) swingle skin are placed in the hot pot dryouied, fry 13 minutes, dry in the air to crisp, grind stand-by;
4. Calamina and Carapax et Plastrum Testudinis are placed in step 1. gained filtrate, soak 35 minutes, forging is crisp, grinds 70 mesh sieves stand-by;
5. by step 2.-4. gains mixing, be placed in fine and close gauze, closing in tighten, adds vinegar, and intense fire is fried open, and turns 18 minutes at a simmer, leaches medicinal liquid and bottle and get final product.
model case three: Zou XX, man, 60 years old, Ling County, Dezhou City Shandong Province.Symptom: suffer from type Ⅱdiabetes mellitus 10 years, complicated with diabetes biped ulcer 1 year, by the agency of is sought medical advice to burn hospital, belongs to 3 grades by this sufferer of wagner classification.
Use embodiment 4 gained Chinese medicine lotion, adhere to that medication is uninterrupted, through the Drug therapy of half a year, traumatic infection is suppressed, the continuous elongation growth of granulation tissue, and surface is covered by epidermis gradually, the tibia exposed the most at last wrap up by skin and flesh, patient's wound surface rehabilitates.
embodiment 5treat a Chinese medicine lotion for diabetic foot, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Radix Cynanchi Atrati 3 parts, 28 parts, Semen Phaseoli, Stigma Croci 3 parts, Radix Rhodiolae 32 parts, Indigo Naturalis 30 parts, Radix Trichosanthis 8 parts, Margarita powder 20 parts, Rosehips oil 6 parts, Flos Lonicerae 10 parts, Cortex Pseudolaricis 30 parts, Fructus Arctii 7 parts, Calamina 20 parts, ailanthus altissima (mill.) swingle skin 10 parts, Carapax et Plastrum Testudinis 4.5 parts.
The preparation method of the Chinese medicine lotion of above-mentioned treatment diabetic foot, step is as follows:
1. be placed in marmite by Semen Phaseoli, add the warm water of Semen Phaseoli weight 15 times, soak 5 hours, little fire puts into appropriate cold water after simmering 60 minutes slowly, then boils 15 minutes, and filter, filtrate is stand-by, and filtering residue pulverizes slagging dries stand-by;
2. by step 1. gained disintegrating slag and Indigo Naturalis, Radix Trichosanthis, Margarita powder, Rosehips oil mixes, and is placed in plate stand-by with preservative film parcel placement 50 minutes;
3. Radix Cynanchi Atrati, Stigma Croci, Radix Rhodiolae, Flos Lonicerae, Cortex Pseudolaricis, Fructus Arctii and ailanthus altissima (mill.) swingle skin are placed in the hot pot dryouied, fry 10 minutes, dry in the air to crisp, grind stand-by;
4. Calamina and Carapax et Plastrum Testudinis are placed in step 1. gained filtrate, soak 30 minutes, forging is crisp, grinds 60 mesh sieves stand-by;
5. by step 2.-4. gains mixing, be placed in fine and close gauze, closing in tighten, adds vinegar, and intense fire is fried open, and turns 15 minutes at a simmer, leaches medicinal liquid and bottle and get final product.
test example:the clinical practice of the Chinese medicine lotion of embodiment 5 gained treatment diabetic foot: screen 240 routine patient with diabetic feet in 4 hospitals, and be divided into two groups at random, experimental group and matched group, experimental group uses the present embodiment 5 products obtained therefrom, and matched group uses other treatment diabetic foot medicine.
Curative effect situation criterion: recovery from illness: after using Chinese medicine lotion of the present invention, malaise symptoms obviously alleviates or disappears; Effective: malaise symptoms alleviates to some extent; Invalid: after using Chinese medicine lotion of the present invention, malaise symptoms is unchanged.Result is as shown in table 1.
Table 1:
Prove through clinical trial, Chinese medicine lotion effective percentage of the present invention is 95.8%, the cure rate of Chinese medicine lotion of the present invention is 94.2%, and treatment safety coefficient is far away higher than surgical operation therapy, the safety coefficient for the treatment of reaches 99%, in clinical observation, have no obvious adverse reaction, be a kind of treat diabetic foot ideal and without any harm medicine.
Claims (10)
1. treat a Chinese medicine lotion for diabetic foot, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Radix Cynanchi Atrati 1-5 part, Semen Phaseoli 20-35 part, Stigma Croci 1-5 part, Radix Rhodiolae 25-40 part, Indigo Naturalis 25-35 part, Radix Trichosanthis 5-12 part, Margarita powder 9-30 part, Rosehips oil 2-9 part, Flos Lonicerae 5-15 part, Cortex Pseudolaricis 25-35 part, Fructus Arctii 5-9 part, Calamina 9-30 part, ailanthus altissima (mill.) swingle skin 5-15 part (preferred proportioning, ailanthus altissima (mill.) swingle skin 5.5-14.5 part), Carapax et Plastrum Testudinis 3-6 part.
2. the Chinese medicine lotion for the treatment of diabetic foot according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Radix Cynanchi Atrati 2-4 part, Semen Phaseoli 25-30 part, Stigma Croci 2-4 part, Radix Rhodiolae 30-35 part, Indigo Naturalis 28-32 part, Radix Trichosanthis 7-10 part, Margarita powder 15-25 part, Rosehips oil 3-7 part, Flos Lonicerae 8-12 part, Cortex Pseudolaricis 28-32 part, Fructus Arctii 6-8 part, Calamina 15-25 part, ailanthus altissima (mill.) swingle skin 8-12 part, Carapax et Plastrum Testudinis 4-5 part.
3. the Chinese medicine lotion for the treatment of diabetic foot according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Radix Cynanchi Atrati 3 parts, 28 parts, Semen Phaseoli, Stigma Croci 3 parts, Radix Rhodiolae 32 parts, Indigo Naturalis 30 parts, Radix Trichosanthis 8 parts, Margarita powder 20 parts, Rosehips oil 6 parts, Flos Lonicerae 10 parts, Cortex Pseudolaricis 30 parts, Fructus Arctii 7 parts, Calamina 20 parts, ailanthus altissima (mill.) swingle skin 10 parts, Carapax et Plastrum Testudinis 4.5 parts.
4. the preparation method of the Chinese medicine lotion of the treatment diabetic foot according to any one of claim 1-3, is characterized in that: step is as follows:
1. be placed in marmite by Semen Phaseoli, add Semen Phaseoli weight 10-20 warm water doubly, soak 4-6 hour, little fire puts into appropriate cold water after simmering 50-70 minute slowly, then boils 10-20 minute, and filter, filtrate is stand-by, and filtering residue pulverizes slagging dries stand-by;
2. by step 1. gained disintegrating slag and Indigo Naturalis, Radix Trichosanthis, Margarita powder, Rosehips oil mixes, be placed in plate with preservative film parcel place 40-60 minute stand-by;
3. Radix Cynanchi Atrati, Stigma Croci, Radix Rhodiolae, Flos Lonicerae, Cortex Pseudolaricis, Fructus Arctii and ailanthus altissima (mill.) swingle skin are placed in the hot pot dryouied, fry 5-15 minute, dry in the air to crisp, grind stand-by;
4. Calamina and Carapax et Plastrum Testudinis are placed in step 1. gained filtrate, soak 20-40 minute, forging is crisp, grinds 40-80 mesh sieve stand-by;
5. by step 2.-4. gains mixing, be placed in fine and close gauze, closing in tighten, adds vinegar, and intense fire is fried open, and turns 10-20 minute at a simmer, leaches medicinal liquid and bottle and get final product.
5. the preparation method of Chinese medicine lotion according to claim 4, it is characterized in that: 1. step adds Semen Phaseoli weight 13-18 warm water doubly, soak 4.5-5.5 hour, little fire is put into appropriate cold water and (is preferably added the warm water of Semen Phaseoli weight 15 times after simmering 55-65 minute slowly, soak 5 hours, little fire puts into appropriate cold water after simmering 60 minutes slowly).
6. the preparation method of Chinese medicine lotion according to claim 4, is characterized in that: 1. step boils 13-18 minute again, filters, filtrate stand-by (preferably boil 15 minutes again, filter, filtrate is stand-by).
7. the preparation method of Chinese medicine lotion according to claim 4, is characterized in that: 2. step is placed in plate and places 45-55 minute stand-by (being preferably placed in plate stand-by with preservative film parcel placement 50 minutes) with preservative film parcel.
8. the preparation method of Chinese medicine lotion according to claim 4, it is characterized in that: 3. Radix Cynanchi Atrati, Stigma Croci, Radix Rhodiolae, Flos Lonicerae, Cortex Pseudolaricis, Fructus Arctii and ailanthus altissima (mill.) swingle skin are placed in the hot pot dryouied by step, fry 8-13 minute (preferably, Radix Cynanchi Atrati, Stigma Croci, Radix Rhodiolae, Flos Lonicerae, Cortex Pseudolaricis, Fructus Arctii and ailanthus altissima (mill.) swingle skin are placed in the hot pot dryouied, fry 10 minutes).
9. the preparation method of Chinese medicine lotion according to claim 4, it is characterized in that: 4. step soaks 25-35 minute, forging is crisp, grinds 50-70 mesh sieve stand-by (preferred, soak 30 minutes, forging is crisp, grinds 60 mesh sieves stand-by).
10. the preparation method of Chinese medicine lotion according to claim 4, is characterized in that: step 5. intense fire is fried open, and turns 13-18 at a simmer minute (preferred, intense fire is fried open, and turns 15 minutes at a simmer).
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106880713A (en) * | 2017-03-24 | 2017-06-23 | 蔡成良 | It is a kind of to prevent foot-bath liquor of diabetes and its preparation method and application |
| CN107156372A (en) * | 2017-04-24 | 2017-09-15 | 南昌大学 | A kind of rose hip oil inulin beauty treatment weight reducing milk tea |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1943721A (en) * | 2006-10-20 | 2007-04-11 | 青岛市市立医院 | A Chinese traditional externally use medicinal composition for treatment of diabetic feet |
| CN102949578A (en) * | 2012-11-28 | 2013-03-06 | 宁夏易欣回药科技有限公司 | Traditional Chinese medicine for treating diabetic foot |
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2015
- 2015-10-14 CN CN201510659705.9A patent/CN105250525A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1943721A (en) * | 2006-10-20 | 2007-04-11 | 青岛市市立医院 | A Chinese traditional externally use medicinal composition for treatment of diabetic feet |
| CN102949578A (en) * | 2012-11-28 | 2013-03-06 | 宁夏易欣回药科技有限公司 | Traditional Chinese medicine for treating diabetic foot |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106880713A (en) * | 2017-03-24 | 2017-06-23 | 蔡成良 | It is a kind of to prevent foot-bath liquor of diabetes and its preparation method and application |
| CN107156372A (en) * | 2017-04-24 | 2017-09-15 | 南昌大学 | A kind of rose hip oil inulin beauty treatment weight reducing milk tea |
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Application publication date: 20160120 |