CN104667076A - Tendon-relaxing and collateral-dredging medicinal wine for treating acute soft tissue injuries - Google Patents
Tendon-relaxing and collateral-dredging medicinal wine for treating acute soft tissue injuries Download PDFInfo
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Abstract
The invention discloses tendon-relaxing and collateral-dredging medicinal wine for treating acute soft tissue injuries. The tendon-relaxing and collateral-dredging medicinal wine is mainly prepared from the following active pharmaceutical ingredients in parts by mass: 6-12 parts of diverse wormwood herb, 5-10 parts of sappan wood, 8-12 parts of common burreed rhizome, 6-9 parts of corydalis tuber, 5-10 parts of fistular onion stalk, 4-9 parts of Japanese dock root, 3-9 parts of Szechuan melandium root, 5-10 parts of earthworm, 9-12 parts of bigflower cape jasmine fruits, 8-15 parts of kusnezoff monkshood root and an appropriate amount of rice wine. The tendon-relaxing and collateral-dredging medicinal wine is summarized from many years of clinical practices, has the effects of activating blood circulation, removing stasis, regulating qi and relieving pain, and has significant curative effects and capability of treating both symptoms and root causes.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine.
Background technology
Acute soft tissue injury mean a series of acute contusion that the tissue outside the following skeleton of human motion system, skin occurs or (with) laceration, comprise the acute injury of different situations of the tissues such as muscle, ligament, fascia, tendon, synovial membrane, fat, joint capsule and peripheral nerve, blood vessel.These tissues are subject to the effect of external or inherent different causative factors of injury, cause and organize the temporary disturbance of acute destruction and tissue physiology's function and produce damage.Acute soft tissue injury is generally the effect by external mechanism's stress, exceedes soft tissue and bears load, can bring out damage, produce symptom when stress reaches certain intensity.Clinical symptoms shows as 1. pain: with the nature and extent of violence, the distribution of injury nerve and the power of inflammatory reaction relevant.2. swelling: because of local soft tissue internal hemorrhage or (with) caused by inflammatory reaction oozes out.3. dysfunction: the obstacle causing limb function or activity.4. wound or wound surface: the violence nature and extent according to damage can have the wound of different depth or skin abrasion etc.
Publication No. CN 103301411 A(application number 201310281418.X) Chinese patent literature disclose a kind of Chinese medicinal liquor for the treatment of soft tissue injury and preparation method thereof, be made up of the raw material of following weight portion: Folium Hibisci Mutabilis 28-42 gram, Radix Angelicae Dahuricae 28-42 gram, Radix Angelicae Sinensis 23-33 gram, Radix Arnebiae (Radix Lithospermi) 23-33 gram, Radix Notoginseng 13-17 gram, Olibanum 13-17 gram, Flos Caryophylli 13-17 gram, Rhizoma Kaempferiae 13-17 gram, Rhizoma Corydalis 10-14 gram, Rhizoma Alismatis 10-14 gram, Rhizoma Coptidis 10-14 gram, Radix Scutellariae 7-11 gram, Radix Paeoniae Rubra 7-11 gram, Flos Carthami 6-8 gram, Cortex Moutan 6-8 gram, Rhizoma Curcumae Longae 6-8 gram, 60 degree of Chinese liquor 4600-6600 gram.Publication No. CN 103169830 A(application number 201310120987.6) Chinese patent literature disclose a kind of exterior-applied medical wine for the treatment of closed soft tissue injury, do not have 10g, Rhizoma Drynariae 10g, Eupolyphaga Seu Steleophaga 10g, Semen Momordicae 10g, Sanguis Draxonis 10g, Typhonium flagelliforme (Lodd.) Blume 10g, Radix Glycyrrhizae 10g by Radix Angelicae Sinensis 10g, Rhizoma Chuanxiong 10g, Radix Et Rhizoma Rhei 10g, Flos Carthami 10g, Radix Aconiti 10g, Radix Aconiti Kusnezoffii 10g, RADIX CODONOPSIS PILOSULAE from Northwest of China 10g, Semen Persicae 10g, breast, 52 degree of Chinese liquor 1kg make.Publication No. CN 104337918 A(application number 201310337815.4) Chinese patent literature disclose and be a kind ofly used for the treatment of the exterior-applied medical wine sprained, it is characterized in that comprising following composition: Radix Aconiti 10 grams, Rhizoma Et Radix Notopterygii 15 grams, Radix Notoginseng 10 grams, Lignum Sappan 25 grams, Herba Lycopi 15 grams, Radix Et Rhizoma Rhei 5 grams, Lignum Sappan 6 grams, white orchid 10 grams, Radix Polygalae 15 grams, strangle party's root 9 grams, alcoholic strength is the Chinese liquor 400 milliliters of 40%.
Though the medicine being applied to treatment acute soft tissue injury at present has much, therapeutic effect differs very large, and some drugs exists the shortcoming of length consuming time, weak curative effect, therefore should work out that clinical effectiveness is more remarkable, the medicine of use safety, instant effect.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take the wide a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine of safe and applicable.
Technical scheme of the present invention is:
A kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine, is prepared from primarily of following bulk drugs, is mass parts: Herba Artemisiae Anomalae 6-12; Lignum Sappan 5-10; Rhizoma Sparganii 8-12; Rhizoma Corydalis 6-9; Bulbus Allii Fistulosi 5-10; Radix Rumicis Japonici 4-9; Radix Melandrii szechuanensis 3-9; Pheretima 5-10; Fructus Gardeniae grandiflorae 9-12; Radix Aconiti Kusnezoffii 8-15; Rice wine is appropriate.
Preferred version is, Herba Artemisiae Anomalae 8-10; Lignum Sappan 6-9; Rhizoma Sparganii 9-11; Rhizoma Corydalis 7-8; Bulbus Allii Fistulosi 6-9; Radix Rumicis Japonici 5-8; Radix Melandrii szechuanensis 4-8; Pheretima 6-9; Fructus Gardeniae grandiflorae 10-11; Radix Aconiti Kusnezoffii 10-13; Rice wine is appropriate.
The scheme be more preferably, Herba Artemisiae Anomalae 9; Lignum Sappan 7.5; Rhizoma Sparganii 10; Rhizoma Corydalis 7.5; Bulbus Allii Fistulosi 7.5; Radix Rumicis Japonici 6.5; Radix Melandrii szechuanensis 6; Pheretima 7.5; Fructus Gardeniae grandiflorae 10.5; Radix Aconiti Kusnezoffii 11.5; Rice wine is appropriate.
The preparation method of described a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine, step is as follows:
(1) get Pheretima removing impurity, clean, cutting, add crude drug quality 0.3-0.5 yellow wine doubly (preferred: the yellow wine adding crude drug quality 0.4 times) and mix thoroughly, after moistening, be placed in heat oil pot, exploding to surface is brown color, takes out, drains oil;
(2) Radix Glycyrrhizae and Semen sojae atricolor are decocted with water filter to obtain soup, get Radix Aconiti Kusnezoffii and clean, be placed in soup and soak and (soak 7-9 hour in 6-10 hour; Be more preferably: soak 8 hours), take out and put into steamer, Steam by water bath, shave, to dry;
(3) Herba Artemisiae Anomalae, Lignum Sappan, Rhizoma Sparganii, Rhizoma Corydalis, Bulbus Allii Fistulosi, Radix Rumicis Japonici, Radix Melandrii szechuanensis and Fructus Gardeniae grandiflorae are cleaned remove impurity, add rice vinegar and clear water (mass ratio of rice vinegar and clear water is 1:3), slow fire heating is boiled to the saturating heart altogether, take out, cut sheet, dry, smash to pieces together with step (1) and (2) made crude drug and sieve;
(4) be added in rice wine by step (3) gained medicated powder, sealing dipping, every day stirs once, and total immersion stain 25-35 days (preferred: dipping 28-32 days; Be more preferably: flood 30 days), get supernatant, squeezing medicinal residues, press liquor and supernatant merge, and stir, sealing and standing, and namely filtration, fill obtain channels sootheing and network vessel quickening medicated wine.
The preparation method of described a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine, step (1) moistening 20-30 hour is (preferred: moistening 22-28 hour; Be more preferably: moistening 25 hours).
The preparation method of described a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine, step (2) Steam by water bath 4-6 hour is (preferred: Steam by water bath 4.5-5.5 hour; Be more preferably: Steam by water bath 5 hours).
The preparation method of described a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine, the 6-8 that the total amount of step (3) rice vinegar and clear water is boiled crude drug quality is (preferred: 7 times that the total amount of rice vinegar and clear water is boiled crude drug quality) doubly.
The preparation method of described a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine, it is (preferred: to smash 80-100 mesh sieve to pieces that step (3) smashed 60-120 mesh sieve to pieces; Be more preferably: smashed 90 mesh sieves to pieces).
The preparation method of described a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine, the amount that step (4) adds rice wine is that the 12-24 of medicated powder quality is doubly (preferred: the amount adding rice wine is 16-20 times of medicated powder quality; Be more preferably: the amount adding rice wine is 18 times of medicated powder quality).
The preparation method of described a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine, step (4) sealing and standing 12-18 days is (preferred: sealing and standing 14-16 days; Be more preferably: sealing and standing 15 days).
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Herba Artemisiae Anomalae: have another name called Herba Artemisiae Anomalae grass, Herba Senecionis Scandentis is the wounded in the battle herb of Compositae sagebruss artemisia anomalas.The property of medicine: stem is cylindrical, surperficial brown color or brown-green, matter is hard and crisp, frangibility, the integrated spike panicle of head inflorescence, withered yellow, gas fragrance, bitter in the mouth, pungent, warm in nature.Composition: mainly containing arteanoflavone, tricin, apigenin, Palmic acid etc.Find according to modern pharmacological research, this medical instrument has effect of anti-hypoxia, blood circulation promoting and blood stasis dispelling, removing food stagnancy, hemostasia and detumescence, for amenorrhea due to stagnation of blood, and abdominal pain due to retention of food, hematuria, the diseases such as scald.
Lignum Sappan: base is former: be the dry duramen of leguminous plant Lignum Sappan.Chemical analysis: woody part is containing colourless protochrome-brazilin about 2%.Brazilin is met air and is namely oxidized to brasilein.Separately containing Lignum Sappan phenol, can organic reagent be done, check aluminium ion.Again containing volatile oil, main body of oil is phellandrene and ocimene.Also containing tannin.Nature and flavor: Gan Xian are flat.Gui Jing: enter the heart, Liver Channel.Function cures mainly: promoting the circulation of blood, removing blood stasis with potent drugs, detumescence, pain relieving.Control married woman's vim and vigour cardiac and abdominal pain, amenorrhea, postnatal blood stasis distending pain dyspnea with rapid respiration, dysentery, tetanus, carbuncle, flutter and damage that the stasis of blood is stagnant has a pain.
Rhizoma Sparganii: base is former: be the tuber of Sparganiaceae plant rhizoma scirpi, spire rhizoma scirpi, little rhizoma scirpi.Nature and flavor: acrid in the mouth; Puckery; Cool.Gui Jing: liver; Spleen channel.Function cures mainly: removing blood stasis circulation of qi promoting; Removing food stagnancy pain relieving.Primary symptom abdominal mass mass in the abdomen; The stagnant amenorrhea of the stasis of blood; Dysmenorrhea; Food stagnation distending pain; Fall the year pain of injury.
Rhizoma Corydalis: base is former: be the tuber of papaveraceae plant corydalis.Nature and flavor: arduous, temperature.Gui Jing: enter liver, stomach warp.Function cures mainly: invigorate blood circulation, and dissipating blood stasis is regulated the flow of vital energy, pain relieving.Control all pains of trusted subordinate's waist knee joint, menoxenia, lump in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.
Bulbus Allii Fistulosi: base is former: be the bulb of liliaceous plant Herba Alii fistulosi.Chemical analysis: bulb is containing volatile oil, and in oil, main component is Bulbus Allii element; Again containing allyl sulfide.Calcium oxalate crystal is had in sheath and squamous cell.Nature and flavor: pungent, temperature.Gui Jing: enter lung, stomach warp.Function cures mainly: deliver, and activates yang, removing toxic substances.The cold and heat that cure the wound are had a headache, and YIN-cold is suffered from abdominal pain, malnutrition due to parasitic infestation internal resistance, constipation and anuresis, dysentery, carbuncle.
Radix Rumicis Japonici: base is former: be the root of polygonaceae plant Radix Rumicis Japonici or Nepal's Radix Rumicis Japonici.Chemical analysis: Radix Rumicis Crispi is containing chrysophanic acid, emodin, Nepodin base-3-methyl naphthalene.Nature and flavor: bitter, cold, slightly poisonous.Gui Jing: " book on Chinese herbal medicine brief points ": " enter meridian of Hand-SHAO YIN." function cures mainly: heat clearing away, relieving constipation, diuretic, hemostasis, parasite killing.Control constipation due to dry stool, stranguria with turbid discharge, jaundice, spit blood, hemorrhoidal hamorrhage, dysfunctional uterine hemorrhage, tinea alba, scabies, carbuncle, traumatic injury.
Radix Melandrii szechuanensis: base is former: be the root of pinkwort Radix Melandrii szechuanensis.Nature and flavor: bitter; Pungent; Cool in nature.Gui Jing: lung; Kidney channel.Function cures mainly: analgesia; Heat clearing away; Diuresis; Reduce phlegm.Main traumatic injury; Rheumatalgia; Gastric abscess; Pyretic stranguria; Cough due to lung-heat; Traumatic hemorrhage; Furuncle toxic swelling.
Pheretima: nature and flavor with return through: salty, cold.Return liver, spleen, urinary bladder channel.There is heat clearing away to calm the frightened, dredging collateral, relieving asthma, effect of diuresis.For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, edema oliguria.
Fructus Gardeniae grandiflorae: base is former: be the fruit of dicotyledon medicine Maguireothamnus speciosus Flos Caryophylli Fructus Gardeniae.Chemical analysis: seed is containing crocin, mannitol, and a kind of fusing point is the composition of 167-168 DEG C, may be phytohormone.Branch skin is containing the polyhydroxy-alcohol such as Sorbitol, mannitol.Nature and flavor: bitter; Cold.Gui Jing: the heart; Liver Channel.Function cures mainly: heat radiation removing toxic substances; Reducing swelling and alleviating pain.Main pyretic toxicity; Jaundice; Epistaxis; Oedema due to nephritis; Contusion is sprained.
Radix Aconiti Kusnezoffii: base is former: be the tuber of ranunculaceae plant Aconitum carmichjaelii Debx. (wild species), Aconitum kusnezoffii Reichb etc.Nature and flavor: pungent; Bitter; Heat; Large poison.Gui Jing: the heart; Liver; Spleen channel.Function cures mainly: expelling wind and removing dampness; Dispelling cold by warming the meridian; Reducing swelling and alleviating pain; .Main anemofrigid-damp arthralgia; Arthralgia; Wind syndrome of head is had a headache; Apoplectic dyscinesia; Trusted subordinate's cold type of pain; Colic of cold type is had a pain; Traumatic injury; Swelling and pain due to blood stasis; Carbuncle of yin nature toxic swelling; Narcotic analgesic.
Rice wine: base is former: a kind of sweet rice wine mixing the fermentation of upper wine ferment with the Oryza glutinosa cooked.Nature and flavor: sweet in the mouth is pungent, warm in nature.Function cures mainly: QI invigorating, promotes the production of body fluid, and invigorates blood circulation.
A kind of acute soft tissue injury channels sootheing and network vessel quickening medicinal liquor prescription science provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, therapeutic effect is good, and cure rate is high, effectively can shorten treatment time;
2, this formula is summed up through clinical practice for many years and is formed, and has effect of blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain;
3, Chinese crude drug selected by the present invention, safety has no side effect, can long-term taking, improves immunity.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Artemisiae Anomalae 6 parts, Lignum Sappan 5 parts, Rhizoma Sparganii 8 parts, Rhizoma Corydalis 6 parts, Bulbus Allii Fistulosi 5 parts, 4 parts, Radix Rumicis Japonici, Radix Melandrii szechuanensis 3 parts, Pheretima 5 parts, Fructus Gardeniae grandiflorae 9 parts, Radix Aconiti Kusnezoffii 8 parts, rice wine is appropriate.The preparation method of above-mentioned a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine is:
(1) get Pheretima removing impurity, clean, cutting, the yellow wine adding crude drug quality 0.3 times is mixed thoroughly, and moistening, after 20 hours, is placed in heat oil pot, and exploding to surface is brown color, takes out, drains oil;
(2) Radix Glycyrrhizae and Semen sojae atricolor are decocted with water filter to obtain soup, get Radix Aconiti Kusnezoffii and clean, be placed in soup and soak 6 hours, take out and put into steamer, Steam by water bath 4 hours, shave, to dry;
(3) Herba Artemisiae Anomalae, Lignum Sappan, Rhizoma Sparganii, Rhizoma Corydalis, Bulbus Allii Fistulosi, Radix Rumicis Japonici, Radix Melandrii szechuanensis and Fructus Gardeniae grandiflorae are cleaned remove impurity, add rice vinegar and clear water (mass ratio of rice vinegar and clear water is 1:3), 6 times that the total amount of rice vinegar and clear water is boiled crude drug quality, slow fire heating is boiled to the saturating heart altogether, take out, cut sheet, dry, smashed 60 mesh sieves to pieces together with step (1) and (2) made crude drug;
(4) step (3) gained medicated powder is added in rice wine, the amount of rice wine is 12 times of medicated powder quality, sealing dipping, every day stirs once, total immersion stain 25 days, get supernatant, squeezing medicinal residues, press liquor and supernatant merge, and stir, sealing and standing 12 days, namely filtration, fill obtain channels sootheing and network vessel quickening medicated wine.
embodiment 2a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Artemisiae Anomalae 12 parts, Lignum Sappan 10 parts, Rhizoma Sparganii 12 parts, Rhizoma Corydalis 9 parts, Bulbus Allii Fistulosi 10 parts, 9 parts, Radix Rumicis Japonici, Radix Melandrii szechuanensis 9 parts, Pheretima 10 parts, Fructus Gardeniae grandiflorae 12 parts, Radix Aconiti Kusnezoffii 15 parts, rice wine is appropriate.The preparation method of above-mentioned a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine is:
(1) get Pheretima removing impurity, clean, cutting, the yellow wine adding crude drug quality 0.5 times is mixed thoroughly, and moistening, after 30 hours, is placed in heat oil pot, and exploding to surface is brown color, takes out, drains oil;
(2) Radix Glycyrrhizae and Semen sojae atricolor are decocted with water filter to obtain soup, get Radix Aconiti Kusnezoffii and clean, be placed in soup and soak 10 hours, take out and put into steamer, Steam by water bath 6 hours, shave, to dry;
(3) Herba Artemisiae Anomalae, Lignum Sappan, Rhizoma Sparganii, Rhizoma Corydalis, Bulbus Allii Fistulosi, Radix Rumicis Japonici, Radix Melandrii szechuanensis and Fructus Gardeniae grandiflorae are cleaned remove impurity, add rice vinegar and clear water (mass ratio of rice vinegar and clear water is 1:3), 8 times that the total amount of rice vinegar and clear water is boiled crude drug quality, slow fire heating is boiled to the saturating heart altogether, take out, cut sheet, dry, smashed 120 mesh sieves to pieces together with step (1) and (2) made crude drug;
(4) step (3) gained medicated powder is added in rice wine, the amount of rice wine is 24 times of medicated powder quality, sealing dipping, every day stirs once, total immersion stain 35 days, get supernatant, squeezing medicinal residues, press liquor and supernatant merge, and stir, sealing and standing 18 days, namely filtration, fill obtain channels sootheing and network vessel quickening medicated wine.
Model case: xxx, women, 22 years old.Medical history: careless traumatic injury when patient's pulley is sliding, arm has scratch, and slight bleeding, left lower limb swelling, livid purple have congestion, hurt like hell, can not walk, and checks through doctor, and patient, without fracture phenomenon, is diagnosed as soft tissue injury.
Take a kind of acute soft tissue injury channels sootheing and network vessel quickening of this example gained medicated wine, each one or two, twice daily, within five days, be a course for the treatment of, after patient takes three days, congestion, pain obviously alleviate, and abrasion takes a turn for the better, after continuing to take a course for the treatment of, left lower limb can normally be walked, without other uncomfortable diseases, in drug withdrawal half a year, all are normal.
embodiment 3a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Artemisiae Anomalae 8 parts, Lignum Sappan 6 parts, Rhizoma Sparganii 9 parts, Rhizoma Corydalis 7 parts, Bulbus Allii Fistulosi 6 parts, 5 parts, Radix Rumicis Japonici, Radix Melandrii szechuanensis 4 parts, Pheretima 6 parts, Fructus Gardeniae grandiflorae 10 parts, Radix Aconiti Kusnezoffii 10 parts, rice wine is appropriate.The preparation method of above-mentioned a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine is:
(1) get Pheretima removing impurity, clean, cutting, the yellow wine adding crude drug quality 0.3 times is mixed thoroughly, and moistening, after 22 hours, is placed in heat oil pot, and exploding to surface is brown color, takes out, drains oil;
(2) Radix Glycyrrhizae and Semen sojae atricolor are decocted with water filter to obtain soup, get Radix Aconiti Kusnezoffii and clean, be placed in soup and soak 7 hours, take out and put into steamer, Steam by water bath 4.5 hours, shave, to dry;
(3) Herba Artemisiae Anomalae, Lignum Sappan, Rhizoma Sparganii, Rhizoma Corydalis, Bulbus Allii Fistulosi, Radix Rumicis Japonici, Radix Melandrii szechuanensis and Fructus Gardeniae grandiflorae are cleaned remove impurity, add rice vinegar and clear water (mass ratio of rice vinegar and clear water is 1:3), 6 times that the total amount of rice vinegar and clear water is boiled crude drug quality, slow fire heating is boiled to the saturating heart altogether, take out, cut sheet, dry, smashed 80 mesh sieves to pieces together with step (1) and (2) made crude drug;
(4) step (3) gained medicated powder is added in rice wine, the amount of rice wine is 16 times of medicated powder quality, sealing dipping, every day stirs once, total immersion stain 28 days, get supernatant, squeezing medicinal residues, press liquor and supernatant merge, and stir, sealing and standing 14 days, namely filtration, fill obtain channels sootheing and network vessel quickening medicated wine.
embodiment 4a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Artemisiae Anomalae 10 parts, Lignum Sappan 9 parts, Rhizoma Sparganii 11 parts, Rhizoma Corydalis 8 parts, Bulbus Allii Fistulosi 9 parts, 8 parts, Radix Rumicis Japonici, Radix Melandrii szechuanensis 8 parts, Pheretima 9 parts, Fructus Gardeniae grandiflorae 11 parts, Radix Aconiti Kusnezoffii 13 parts, rice wine is appropriate.The preparation method of above-mentioned a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine is:
(1) get Pheretima removing impurity, clean, cutting, the yellow wine adding crude drug quality 0.5 times is mixed thoroughly, and moistening, after 28 hours, is placed in heat oil pot, and exploding to surface is brown color, takes out, drains oil;
(2) Radix Glycyrrhizae and Semen sojae atricolor are decocted with water filter to obtain soup, get Radix Aconiti Kusnezoffii and clean, be placed in soup and soak 9 hours, take out and put into steamer, Steam by water bath 5.5 hours, shave, to dry;
(3) Herba Artemisiae Anomalae, Lignum Sappan, Rhizoma Sparganii, Rhizoma Corydalis, Bulbus Allii Fistulosi, Radix Rumicis Japonici, Radix Melandrii szechuanensis and Fructus Gardeniae grandiflorae are cleaned remove impurity, add rice vinegar and clear water (mass ratio of rice vinegar and clear water is 1:3), 8 times that the total amount of rice vinegar and clear water is boiled crude drug quality, slow fire heating is boiled to the saturating heart altogether, take out, cut sheet, dry, smashed 100 mesh sieves to pieces together with step (1) and (2) made crude drug;
(4) step (3) gained medicated powder is added in rice wine, the amount of rice wine is 20 times of medicated powder quality, sealing dipping, every day stirs once, total immersion stain 32 days, get supernatant, squeezing medicinal residues, press liquor and supernatant merge, and stir, sealing and standing 16 days, namely filtration, fill obtain channels sootheing and network vessel quickening medicated wine.
Model case: xxx, male, 38 years old.Main suit: waist swelling, hurt like hell three days; Medical history: patient is before three days during dry weight muscular labor, accidentally sprain waist, just started to feel not serious, then do not pay attention to, evening is hurt like hell in bed, there is swelling in waist both sides, there is ecchymosis in local, limb activity is restricted, to hospital through x-ray inspection, do not find dislocation or fracture, be diagnosed as articular sprain.
After infusion treatment, effect is not remarkable, just goes home to seek additive method; take a kind of acute soft tissue injury channels sootheing and network vessel quickening of this example gained medicated wine upon somebody's introduction, each one or two, twice daily; within five days, be a course for the treatment of, after patient takes one week, sensation flank pain alleviates; ecchymosis starts to disappear, and holds on and takes a course for the treatment of, and uncomfortable disease is eliminated; limbs can normal activity, is consolidate curative effect, continues again to take a course for the treatment of; follow up a case by regular visits in 1 year, do not occur sequela.
embodiment 5a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine, be prepared from (every part of 10g) primarily of following bulk drugs: Herba Artemisiae Anomalae 9 parts, Lignum Sappan 7.5 parts, Rhizoma Sparganii 10 parts, Rhizoma Corydalis 7.5 parts, Bulbus Allii Fistulosi 7.5 parts, 6.5 parts, Radix Rumicis Japonici, Radix Melandrii szechuanensis 6 parts, Pheretima 7.5 parts, Fructus Gardeniae grandiflorae 10.5 parts, Radix Aconiti Kusnezoffii 11.5 parts, rice wine is appropriate.The preparation method of above-mentioned a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine is:
(1) get Pheretima removing impurity, clean, cutting, the yellow wine adding crude drug quality 0.4 times is mixed thoroughly, and moistening, after 25 hours, is placed in heat oil pot, and exploding to surface is brown color, takes out, drains oil;
(2) Radix Glycyrrhizae and Semen sojae atricolor are decocted with water filter to obtain soup, get Radix Aconiti Kusnezoffii and clean, be placed in soup and soak 8 hours, take out and put into steamer, Steam by water bath 5 hours, shave, to dry;
(3) Herba Artemisiae Anomalae, Lignum Sappan, Rhizoma Sparganii, Rhizoma Corydalis, Bulbus Allii Fistulosi, Radix Rumicis Japonici, Radix Melandrii szechuanensis and Fructus Gardeniae grandiflorae are cleaned remove impurity, add rice vinegar and clear water (mass ratio of rice vinegar and clear water is 1:3), 7 times that the total amount of rice vinegar and clear water is boiled crude drug quality, slow fire heating is boiled to the saturating heart altogether, take out, cut sheet, dry, smashed 90 mesh sieves to pieces together with step (1) and (2) made crude drug;
(4) step (3) gained medicated powder is added in rice wine, the amount of rice wine is 18 times of medicated powder quality, sealing dipping, every day stirs once, total immersion stain 30 days, get supernatant, squeezing medicinal residues, press liquor and supernatant merge, and stir, sealing and standing 15 days, namely filtration, fill obtain channels sootheing and network vessel quickening medicated wine.
test example 1the clinical practice of a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine (embodiment 5) of gained of the present invention:
Choose crowd: in January ,-2015 in March, 2014, according to medical case history, suffer from patient 367 example of acute soft tissue injury four hospitals' screenings, age 12-55 year, 34.9 ± 1.8 years old mean age, wherein male patient 196 example, female patient 171 example.Western medicine diagnose standard: (1) soft tissue contusion: 1 has obvious trauma history, sharp ache, local swelling rapidly, limb activity dysfunction; 2 injury tenderness are obvious, can occur the livid purple congestion speckle in local, can occur ecchymosis time serious, and fluctuation disease is positive; 3 latter about two weeks of damages, silt tumescence disappears or transfers yellowish-brown to, and pain alleviates gradually, functional rehabilitation or slight obstacle; 4 minorities damage comparatively severe patient, and convalescent period is longer, and local still has swelling or scleroma, has a dull ache, and it is limited that limb activity has in various degree, and x-ray inspection mainly gets rid of fracture, dislocate and osteopathia etc.(2) articular sprain: 1 has in early days and significantly sprains history, there is swelling in various degree, ecchymosis, joint movement disorder in sharp ache after wound, local; After 2 injured 3-4 days mid-terms, swelling starts to disappear, the livid purple color that shoals gradually of ecchymosis, and skin temperature is high, and decrescence, joint motion is still limited for pain; After 3 later stage joint injuries two weeks, silt tumescence disappears, and ecchymosis becomes yellowish-brown, and pain fades, and function major part is recovered, and it is longer that minority damages serious patient's convalescent period, and local still has scleroma, and have a dull ache, joint is limited, protracted course of disease; Fracture, dislocation and osteopathia etc. are mainly got rid of in 4 x-ray inspections, sometimes have certain reference value to the damage of tendon, ligament and cartilage.
Before test, patient is divided into two groups at random, experimental group 237 example and matched group 130 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes a kind of acute soft tissue injury channels sootheing and network vessel quickening of gained of the present invention medicated wine, and each one or two, twice daily, within five days, be a course for the treatment of; Matched group takes other conventional medicines (Votalin Ointment, Yunnan Baiyao Capsule, invigorate blood circulation bone knitting powder or tablet for relieving rigidity of muscles and promoting blood circulation etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: pain and swelling disappears completely, and without pressure pain point, ecchymosis disappears, and local function recovers normal, and activity reaches normal range; (2) effective: pain and swelling disappears substantially, affected part or have slight tenderness, functional activity recovers or close to normal, ecchymosis area obviously reduces; (3) effective: pain and swelling obviously alleviates, and affected part still has tenderness, function makes moderate progress comparatively before, and ecchymosis area reduces; (4) invalid: each symptom and sign are not improved.
Clinical effectiveness: after the taking medicine of two courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
As shown in Table 1, after treating a course for the treatment of, the healing patient of experimental group is 116 examples, cure rate is 48.9%, and effective patient is 42 examples, and obvious effective rate is 17.7%, effective patient is 57 examples, and effective percentage is 24.1%, and total effective rate is 90.7%, and the patient that matched group is cured is 34 examples, cure rate is 26.2%, and effective patient is 25 examples, obvious effective rate is 19.2%, and effective patient is 41 examples, and effective percentage is 31.5%, total effective rate 76.9%, significantly lower than the therapeutic effect of experimental group; Through the treatment of two courses for the treatment of, the total effective rate of experimental group reaches 97.9%, is obviously better than the total effective rate 83.8% of matched group, and products obtained therefrom short treating period of the present invention, instant effect are described.
The Chinese medicine used in the present invention, Herba Artemisiae Anomalae can blood circulation promoting and blood stasis dispelling, and Lignum Sappan can reducing swelling and alleviating pain, Rhizoma Sparganii can removing blood stasis circulation of qi promoting, and Rhizoma Corydalis can promoting blood circulation to remove blood stasis, and Bulbus Allii Fistulosi can be activated yang removing toxic substances, Radix Rumicis Japonici can clearing away heat to stop bleeding, and Radix Melandrii szechuanensis can ease pain heat clearing away, and Pheretima can be relievingd asthma by dredging collateral, Fructus Gardeniae grandiflorae can reducing swelling and alleviating pain, Radix Aconiti Kusnezoffii can dispelling cold by warming the meridian, and multiple medical material synergism, adds benefiting QI for activating blood circulation effect of rice wine, effectively can treat acute soft tissue injury, alleviate uncomfortable disease.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. an acute soft tissue injury channels sootheing and network vessel quickening medicated wine, is characterized in that, is prepared from primarily of following bulk drugs, is mass parts: Herba Artemisiae Anomalae 6-12; Lignum Sappan 5-10; Rhizoma Sparganii 8-12; Rhizoma Corydalis 6-9; Bulbus Allii Fistulosi 5-10; Radix Rumicis Japonici 4-9; Radix Melandrii szechuanensis 3-9; Pheretima 5-10; Fructus Gardeniae grandiflorae 9-12; Radix Aconiti Kusnezoffii 8-15; Rice wine is appropriate.
2. a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine as claimed in claim 1, is characterized in that, Herba Artemisiae Anomalae 8-10; Lignum Sappan 6-9; Rhizoma Sparganii 9-11; Rhizoma Corydalis 7-8; Bulbus Allii Fistulosi 6-9; Radix Rumicis Japonici 5-8; Radix Melandrii szechuanensis 4-8; Pheretima 6-9; Fructus Gardeniae grandiflorae 10-11; Radix Aconiti Kusnezoffii 10-13; Rice wine is appropriate.
3. a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine as claimed in claim 1, is characterized in that, Herba Artemisiae Anomalae 9; Lignum Sappan 7.5; Rhizoma Sparganii 10; Rhizoma Corydalis 7.5; Bulbus Allii Fistulosi 7.5; Radix Rumicis Japonici 6.5; Radix Melandrii szechuanensis 6; Pheretima 7.5; Fructus Gardeniae grandiflorae 10.5; Radix Aconiti Kusnezoffii 11.5; Rice wine is appropriate.
4. the preparation method of a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine as described in as arbitrary in claim 1-3, it is characterized in that, step is as follows:
(1) get Pheretima removing impurity, clean, cutting, add crude drug quality 0.3-0.5 yellow wine doubly (preferred: the yellow wine adding crude drug quality 0.4 times) and mix thoroughly, after moistening, be placed in heat oil pot, exploding to surface is brown color, takes out, drains oil;
(2) Radix Glycyrrhizae and Semen sojae atricolor are decocted with water filter to obtain soup, get Radix Aconiti Kusnezoffii and clean, be placed in soup and soak and (soak 7-9 hour in 6-10 hour; Be more preferably: soak 8 hours), take out and put into steamer, Steam by water bath, shave, to dry;
(3) Herba Artemisiae Anomalae, Lignum Sappan, Rhizoma Sparganii, Rhizoma Corydalis, Bulbus Allii Fistulosi, Radix Rumicis Japonici, Radix Melandrii szechuanensis and Fructus Gardeniae grandiflorae are cleaned remove impurity, add rice vinegar and clear water (mass ratio of rice vinegar and clear water is 1:3), slow fire heating is boiled to the saturating heart altogether, take out, cut sheet, dry, smash to pieces together with step (1) and (2) made crude drug and sieve;
(4) be added in rice wine by step (3) gained medicated powder, sealing dipping, every day stirs once, and total immersion stain 25-35 days (preferred: dipping 28-32 days; Be more preferably: flood 30 days), get supernatant, squeezing medicinal residues, press liquor and supernatant merge, and stir, sealing and standing, and namely filtration, fill obtain channels sootheing and network vessel quickening medicated wine.
5. the preparation method of a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine as claimed in claim 4, is characterized in that, step (1) moistening 20-30 hour (preferred: moistening 22-28 hour; Be more preferably: moistening 25 hours).
6. the preparation method of a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine as claimed in claim 4, is characterized in that, step (2) Steam by water bath 4-6 hour (preferred: Steam by water bath 4.5-5.5 hour; Be more preferably: Steam by water bath 5 hours).
7. the preparation method of a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine as claimed in claim 4, it is characterized in that, the 6-8 that the total amount of step (3) rice vinegar and clear water is boiled crude drug quality is (preferred: 7 times that the total amount of rice vinegar and clear water is boiled crude drug quality) doubly.
8. the preparation method of a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine as claimed in claim 4, is characterized in that, it is (preferred: to smash 80-100 mesh sieve to pieces that step (3) smashed 60-120 mesh sieve to pieces; Be more preferably: smashed 90 mesh sieves to pieces).
9. the preparation method of a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine as claimed in claim 4, is characterized in that, the amount that step (4) adds rice wine is that the 12-24 of medicated powder quality is doubly (preferred: the amount adding rice wine is 16-20 times of medicated powder quality; Be more preferably: the amount adding rice wine is 18 times of medicated powder quality).
10. the preparation method of a kind of acute soft tissue injury channels sootheing and network vessel quickening medicated wine as claimed in claim 4, is characterized in that, step (4) sealing and standing 12-18 days is (preferred: sealing and standing 14-16 days; Be more preferably: sealing and standing 15 days).
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| CN1365685A (en) * | 2001-01-15 | 2002-08-28 | 杨孟君 | Nano medicine for reating bone fracture and injury and its preparing process |
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| CN103830485A (en) * | 2012-11-28 | 2014-06-04 | 马俊杰 | Preparation process of traumatic injury medicinal liquor |
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| CN1365685A (en) * | 2001-01-15 | 2002-08-28 | 杨孟君 | Nano medicine for reating bone fracture and injury and its preparing process |
| CN102988566A (en) * | 2012-11-25 | 2013-03-27 | 溧阳市天目湖保健品有限公司 | Traditional Chinese medicine composition for treating soft tissue injury and preparation method thereof |
| CN103830485A (en) * | 2012-11-28 | 2014-06-04 | 马俊杰 | Preparation process of traumatic injury medicinal liquor |
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Address after: Qinglong Road, Hanzhoung District Court 723000 city of Shaanxi province Hantai District No. 4 1-802 Applicant after: Chen Zhijian Address before: 250000 Ji'nan, China Hi tech Zone, Shandong Chong Hua Road, No. 1587 Applicant before: Chen Zhijian |
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Application publication date: 20150603 |