CN104971138A - Preparation for treating constipation and preparation method thereof - Google Patents
Preparation for treating constipation and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a preparation for treating constipation. The preparation is prepared from the following medicinal raw materials in parts by mass: 10-17 parts of bunge cherry seeds, 8-16 parts of leave of hovenia, 10-16 parts of black jujube, 9-14 parts of fruit of purple perilla, 6-12 parts of semen cannabis, 11-17 parts of fructus forsythiae, 9-16 parts of Common Russianthistle Herb, 12-18 parts of Angelica sinensis, 8-13 parts of Coffee senna fruit or seed, 7-14 parts of Prunus serrulata, 6-11 parts of Rumex japonicus Houtt leaves, 9-12 parts of Morinda parvifolia, 10-15 parts of Morinda parvifolia, 8-12 parts of Long Stephania Herb, 9-15 parts of Herb of Tibet Lancea and 7-16 parts of plantain seed. The preparation disclosed by the invention is obtained by summary of clinical practice of many years, has the efficacies of relaxing bowel, strengthening spleen and benefiting qi and is obvious in curative effect.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to preparation for the treatment of constipation and preparation method thereof.
Background technology
Constipation is clinical common complicated symptom, instead of a kind of disease, mainly refers to that defecation frequency reduces, feces amount reduces, dry and hard, the defecation effort of feces etc.Constipation can affect the people of each age group.Women is more than male, old more than blue or green, the prime of life.Because constipation sickness rate is high, the cause of disease is complicated, patient often has manifold vexations, and can affect quality of life when constipation is serious.Constipation often shows as: awareness of defecation is few, just secondary also few; Defecation is difficult, effort; Defecation is not smooth; Constipation with dry stool, hard just, defecation is not felt only; Constipation is with stomachache or abdominal discomfort.Some patients is also with Behavioral disturbances such as insomnia, agitation, dreaminess, depression, anxieties.
Publication No. CN 104208340 A(application number 201410354847.X) Chinese patent literature disclose a kind of Chinese medicine for the treatment of constipation, pressed certain weight ratio synthesized by Semen Persicae, Fructus Cannabis, Semen Sesami Nigrum, Galla Chinensis, Radix Sophorae Flavescentis, Rhizoma Cyperi, Semen Castaneae, Radix melastomatis candidi, Flos Lonicerae, Mel, there is effect of benefiting QI and nourishing blood, loosening bowel to relieve constipation, promoting blood circulation and stopping pain.Publication No. CN 104706799 A(application number 201310682500.3) Chinese patent literature disclose a kind of Chinese medicine for the treatment of constipation, be made up of the raw material of following parts by weight: Fructus Aurantii Immaturus 5-15 part, Herba Melandrii Aprici 2-4 part, Caulis Bauhiniae Championii 1-3 part, Radix Angelicae Sinensis 3-5 part, Herba Apocyni veneti 3-5 part, Radix Paeoniae Alba 2-10 part, Rhizoma Atractylodis Macrocephalae 5-15 part, Fructus Cannabis 5-10 part, Radix Rehmanniae Preparata 2-10 part, Radix Astragali 5-10 part.Publication No. CN 104510871A(application number 201310469984.3) Chinese patent literature disclose a kind of Chinese medicine for the treatment of constipation, be made up of by weight following Chinese medicinal components: Semen Persicae 30-50 part, Fructus Mori 30-50 part, Radix Et Rhizoma Rhei 30-50 part, Pericarpium Arecae 10-20 part, Herba Melandrii Aprici 10-20 part, Semen Platycladi 30-50 part, ten liang of leaf 10-20 parts, Radix Amaranthi Caudati 10-20 part.
The medicine for the treatment of constipation mostly can only temporary relief of symptoms, can not treating both the principal and secondary aspects of a disease, and some medicine long-term taking, easily produces dependency and zest, and therefore the Chinese medicine formula that has no side effect of a kind of evident in efficacy, safety, is the optimum selection of constipation patient.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, the preparation taking the wide treatment constipation of safe and applicable and preparation method thereof.
Technical scheme of the present invention is:
The preparation for the treatment of constipation, is prepared from primarily of following bulk drugs, is mass parts: Semen Pruni 10-17; Folium Hoveniae 8-16; Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) 10-16; Fructus Perillae 9-14; Fructus Cannabis 6-12; Fructus Forsythiae 11-17; Herba Salsolae Collinae 9-16; Radix Angelicae Sinensis 12-18; Semen Cassiae Occidemtalis 8-13; Fructus Pruni Tomentosae 7-14; Folium Rumicis Japonici 6-11; Herba Morindae Parvifoliae 9-12; Herba Cistanches 10-15; Herba Stephaniae Longae 8-12; Herba Lanceae Tibeticae 9-15; Semen Plantaginis 7-16.
Preferred version is, Semen Pruni 12-15; Folium Hoveniae 10-14; Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) 11-15; Fructus Perillae 10-13; Fructus Cannabis 8-10; Fructus Forsythiae 13-15; Herba Salsolae Collinae 11-14; Radix Angelicae Sinensis 14-16; Semen Cassiae Occidemtalis 9-12; Fructus Pruni Tomentosae 9-12; Folium Rumicis Japonici 7-10; Herba Morindae Parvifoliae 10-11; Herba Cistanches 11-14; Herba Stephaniae Longae 9-11; Herba Lanceae Tibeticae 11-13; Semen Plantaginis 9-14.
More preferably, Semen Pruni 13.5; Folium Hoveniae 12; Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) 13; Fructus Perillae 11.5; Fructus Cannabis 9; Fructus Forsythiae 14; Herba Salsolae Collinae 12.5; Radix Angelicae Sinensis 15; Semen Cassiae Occidemtalis 10.5; Fructus Pruni Tomentosae 10.5; Folium Rumicis Japonici 8.5; Herba Morindae Parvifoliae 10.5; Herba Cistanches 12.5; Herba Stephaniae Longae 10; Herba Lanceae Tibeticae 12; Semen Plantaginis 11.5.
The preparation of described treatment constipation, be made into pharmaceutically acceptable soft extract, its preparation method is:
(1) get Semen Pruni, Fructus Cannabis, Fructus Forsythiae, Semen Cassiae Occidemtalis and Semen Plantaginis remove impurity to clean, be placed in pot, drench into oil, big fire stir-fry 4-10 minute (preferred: big fire stir-fries 6-8 minute; Be more preferably: big fire stir-fries 7 minutes), take out, pulverize, add salt water infiltration 15 minutes, slow fire dries, and takes out;
(2) get Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.), Fructus Perillae and Fructus Pruni Tomentosae to clean, add rice wine and boil to well-done, take out and be placed in baking box, 110 DEG C of constant temperature toast 12-24 minute (preferably: constant temperature baking 16-20 minute; Be more preferably: constant temperature toasts 18 minutes), take out and pulverize together with step (1) made crude drug;
(3) Folium Hoveniae and Folium Rumicis Japonici are cleaned chopping, add rice vinegar and mix thoroughly, moistening 16-24 minute (preferred: moistening 18-22 minute; Be more preferably: moistening 20 minutes), take out, put into frying pan, moderate heat is fried to surperficial zoom, takes out;
(4) Herba Salsolae Collinae, Radix Angelicae Sinensis, Herba Morindae Parvifoliae, Herba Cistanches, Herba Stephaniae Longae and Herba Lanceae Tibeticae are cleaned remove impurity, be placed in marmite, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times), intense fire is heated to boiling, add step (3) made crude drug again, turn little fire to decoct, after filtration, collect filtrate;
(5) blend step (2) (4) gained medicated powder and filtrate, heating is concentrated into thick paste, obtains soft extract.
The preparation method of the preparation soft extract of described treatment constipation, step (4) turns little fire and decocts 18-26 minute (preferably: turn little fire and decoct 20-24 minute; Be more preferably: turn little fire and decoct 22 minutes).
The preparation of described treatment constipation, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Semen Pruni, Fructus Cannabis, Fructus Forsythiae, Semen Cassiae Occidemtalis and Semen Plantaginis remove impurity to clean, be placed in pot, drench into oil, big fire stir-fry 4-10 minute (preferred: big fire stir-fries 6-8 minute; Be more preferably: big fire stir-fries 7 minutes), take out, pulverize, add salt water infiltration 15 minutes, slow fire dries, and takes out;
(2) get Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.), Fructus Perillae and Fructus Pruni Tomentosae to clean, add rice wine and boil to well-done, take out and be placed in baking box, 110 DEG C of constant temperature toast 12-24 minute (preferably: constant temperature baking 16-20 minute; Be more preferably: constant temperature toasts 18 minutes), take out;
(3) Folium Hoveniae and Folium Rumicis Japonici are cleaned chopping, add rice vinegar and mix thoroughly, moistening 16-24 minute (preferred: moistening 18-22 minute; Be more preferably: moistening 20 minutes), take out, put into frying pan, moderate heat is fried to surperficial zoom, takes out;
(4) Herba Salsolae Collinae, Radix Angelicae Sinensis, Herba Morindae Parvifoliae, Herba Cistanches, Herba Stephaniae Longae and Herba Lanceae Tibeticae are cleaned remove impurity, be placed in marmite, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times), intense fire is heated to boiling, add step (3) made crude drug again, turn little fire and decoct 18-26 minute (preferably: turn little fire and decoct 20-24 minute; Be more preferably: turn little fire and decoct 22 minutes), after filtration, collect filtrate;
(5) heat concentration step (4) gained filtrate, pulverize and sieve together with step (1) (2) made crude drug after drying, obtain powder.
The preparation method of the preparation powder of described treatment constipation, it is (preferred: to pulverize 160-200 mesh sieve that step (5) pulverized 130-230 mesh sieve; Be more preferably: pulverized 180 mesh sieves).
The preparation of described treatment constipation, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Semen Pruni, Fructus Cannabis, Fructus Forsythiae, Semen Cassiae Occidemtalis and Semen Plantaginis remove impurity to clean, be placed in pot, drench into oil, big fire stir-fry 4-10 minute (preferred: big fire stir-fries 6-8 minute; Be more preferably: big fire stir-fries 7 minutes), take out, pulverize, add salt water infiltration 15 minutes, slow fire dries, and takes out;
(2) get Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.), Fructus Perillae and Fructus Pruni Tomentosae to clean, add rice wine and boil to well-done, take out and be placed in baking box, 110 DEG C of constant temperature toast 12-24 minute (preferably: constant temperature baking 16-20 minute; Be more preferably: constant temperature toasts 18 minutes), take out and pulverize together with step (1) made crude drug;
(3) Folium Hoveniae and Folium Rumicis Japonici are cleaned chopping, add rice vinegar and mix thoroughly, moistening 16-24 minute (preferred: moistening 18-22 minute; Be more preferably: moistening 20 minutes), take out, put into frying pan, moderate heat is fried to surperficial zoom, takes out;
(4) Herba Salsolae Collinae, Radix Angelicae Sinensis, Herba Morindae Parvifoliae, Herba Cistanches, Herba Stephaniae Longae and Herba Lanceae Tibeticae are cleaned remove impurity, be placed in marmite, decoct with water, intense fire is heated to boiling, add step (3) made crude drug again, turn little fire and decoct 18-26 minute (preferably: turn little fire and decoct 20-24 minute; Be more preferably: turn little fire and decoct 22 minutes), after filtration, collect filtrate;
(5) blend step (2) (4) made medicated powder and filtrate, heating is concentrated into the half of original volume, obtains decoction.
The preparation method of the preparation decoction of described treatment constipation, the 6-9 that step (4) amount of water is boiled crude drug quality is doubly (preferred: the 7-8 that amount of water is boiled crude drug quality is doubly; Be more preferably: amount of water is 7.5 times of boiled crude drug quality).
The preparation of described treatment constipation, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get Semen Pruni, Fructus Cannabis, Fructus Forsythiae, Semen Cassiae Occidemtalis and Semen Plantaginis remove impurity to clean, be placed in pot, drench into oil, big fire stir-fry 4-10 minute (preferred: big fire stir-fries 6-8 minute; Be more preferably: big fire stir-fries 7 minutes), take out, pulverize, add salt water infiltration 15 minutes, slow fire dries, and takes out;
(2) get Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.), Fructus Perillae and Fructus Pruni Tomentosae to clean, add rice wine and boil to well-done, take out and be placed in baking box, 110 DEG C of constant temperature toast 12-24 minute (preferably: constant temperature baking 16-20 minute; Be more preferably: constant temperature toasts 18 minutes), take out;
(3) Folium Hoveniae and Folium Rumicis Japonici are cleaned chopping, add rice vinegar and mix thoroughly, moistening 16-24 minute (preferred: moistening 18-22 minute; Be more preferably: moistening 20 minutes), take out, put into frying pan, moderate heat is fried to surperficial zoom, takes out;
(4) Herba Salsolae Collinae, Radix Angelicae Sinensis, Herba Morindae Parvifoliae, Herba Cistanches, Herba Stephaniae Longae and Herba Lanceae Tibeticae are cleaned remove impurity, be placed in marmite, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times), intense fire is heated to boiling, add step (3) made crude drug again, turn little fire and decoct 18-26 minute (preferably: turn little fire and decoct 20-24 minute; Be more preferably: turn little fire and decoct 22 minutes), after filtration, collect filtrate;
(5) spray drying step (4) gained filtrate, pulverizes and sieves dry thing, adds refined honey water together with step (1) (2) made crude drug, generally makes ball, dry packing, obtains pill.
The preparation method of the preparation pill of described treatment constipation, it is (preferred: to pulverize 90-110 mesh sieve that step (5) pulverized 80-120 mesh sieve; Be more preferably: pulverized 100 mesh sieves).
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Semen Pruni: base is former: for strongly fragrant Lee of the strongly fragrant cherry of Rosaceae, Prunus humilis and flowering plum platymiscium flowering plum, grow the kernel obstructing almond etc.Composition: 1. strongly fragrant Lee: seed contains amygdaloside, prunuside A, B; 2 kinds of protein component: IR-A and IR-B.Fresh fruit, containing multiflorin A, B, is namely prunuside A, B; Also containing ursolic acid, vanillic acid, protocatechuic acid, afzclin, Rhizoma Kaempferiae glycosides, rosamultin.2. Prunus humilis: seed contains amygdaloside, prunuside A, B.3. cerasus nakaii: seed contains amygdaloside, prunuside A, B.4. Radix seu semen Pruni dictyneurae: seed contains amygdaloside, prunuside A, B.The property of medicine: pungent, bitter, sweet, flat.Return spleen, large intestine, small intestine meridian.Function cures mainly: loosening bowel to relieve constipation, therapeutic method to keep the adverse QI flowing downwards diuretic.Cure mainly dryness of the intestine constipation, dysuria, edema abdominal distention, beriberi.
Folium Hoveniae: base is former: be the leaf of Rhamnaceae plant Semen Hoveniae, Semen Hoveniae (Fructus Hoveniae) and comospore Semen Hoveniae (Fructus Hoveniae).Nature and flavor: bitter in the mouth; Cool in nature.Gui Jing: stomach; Liver Channel.Function cures mainly: heat-clearing and toxic substances removing; Relieving restlessness is quenched the thirst.Main anemopyretic cold; Drunk excessive thirst; Vomiting; Constipation.
Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.): base is former: be the fruit of Rhamnaceae plant fineflower buckthorn.Nature and flavor: bitter; Puckery; Flat.Gui Jing: the heart; Spleen; Kidney channel.Function cures mainly: relieving dyspepsia; Row water can be just.Main dyspeptic abdominal distention; Edema; Ascites; Constipation.
Fructus Perillae: base is former: be the fruit of labiate Folium Perillae and wild Folium Perillae.Nature and flavor: acrid in the mouth; Warm in nature.Gui Jing: return lung; Large intestine channel.Function cures mainly: sending down the abnormal ascending QI; Expectorant; Relieving asthma; Intestine moistening.Main expectorant stops up QI rising in reverse order; Cough and asthma; Dryness of the intestine constipation.
Fructus Cannabis: base is former: be the kernel of moraceae plants Fructus Cannabis.Nature and flavor: sweet; Property is put down.Gui Jing: spleen; Stomach; Large intestine channel.Function cures mainly: moisturize laxation; Relieving stranguria by diuresis; Invigorate blood circulation.Main dryness of the intestine constipation; Migratory arthralgia; Quench one's thirst; Edema due to wind pathogen; Pyretic stranguria; Dysentery; Menoxenia; Skin ulcer tinea; Erysipelas.
Fructus Forsythiae: nature and flavor with return through: bitter, be slightly cold.Return lung, the heart, small intestine meridian; There is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, effect of dispelling wind and heat pathogens; For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warm people battalion, high hot excessive thirst, coma sends out speckle, the puckery pain of pyretic stranguria.
Herba Salsolae Collinae: base is former: be the herb of chenopod Herba Salsolae Collinae.Nature and flavor: light; Cool in nature.Gui Jing: Liver Channel.Function cures mainly: suppressing the hyperactive liver and subsiding YANG; Loosening bowel to relieve constipation.Main hypertension; How sick; Dizzy; Insomnia; Dryness of the intestine constipation.
Radix Angelicae Sinensis: nature and flavor with return through sweet, acrid, warm.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine constipation.
Semen Cassiae Occidemtalis: base is former: be the seed of leguminous plant Herba cassiae occidentalis.Nature and flavor: sweetness and bitterness; Cool; Poisonous.Gui Jing: liver; Stomach; Large intestine channel.Function cures mainly: liver heat removing, stomach invigorating, relieving constipation, removing toxic substances.Main conjunctival congestion and swelling pain, dizzy feeling of fullness in the head, dyspepsia, stomachache, dysentery, constipation, carbuncle furunculosis.
Fructus Pruni Tomentosae: base is former: be the fruit of rosaceous plant Fructus Pruni Tomentosae.Nature and flavor: pungent; Sweet; Flat; Nontoxic.Gui Jing: spleen; Kidney channel.Function cures mainly: spleen invigorating, QI invigorating, controlling nocturnal emission with astringent drugs.Staple food amasss dysentery, constipation, beriberi, seminal emission lingering diarrhea.
Folium Rumicis Japonici: base is former: be the leaf of polygonaceae plant Radix Rumicis Japonici or Nepal's Radix Rumicis Japonici.Nature and flavor: sweet; Cold in nature.Function cures mainly: cooling blood for hemostasis; Relieving constipation; Removing toxic substances and promoting subsidence of swelling; Killing parasites for relieving itching.Main discharging fresh blood stool; Constipation; Infantile malnutrition carbuncle pyogenic infections from tumour or sore; Scabies.
Herba Morindae Parvifoliae: base is former: be the Herb of dicotyledon medicine Maguireothamnus speciosus spire Radix Morindae Officinalis.Nature and flavor: sweet; Cool.Gui Jing: lung meridian.Function cures mainly: heat-clearing and toxic substances removing; Eliminating stasis to stop pain; Stomach function regulating removing dampness.Main cold cough; Pertussis; Dyspepsia; Eczema; Traumatic injury, lumbar muscle strain.
Herba Cistanches: base is former: be the fleshy stem of orobanchaceae plant cistanche.Nature and flavor: sweet in the mouth; Salty; Warm in nature.Gui Jing: return kidney; Large intestine channel.Function cures mainly: kidney-replenishing; Benefiting essence-blood; Intestine moistening road.Main kidney yang deficiency; The sexual impotence of asthenia of essence and blood; Seminal emission; Nebulousurine; The frequent micturition heeltap; Lumbago flaccidity of the lower limbs; Tinnitus order flower; Menstruation is spread out the phase; Infertility; Dryness of the intestine constipation.
Herba Stephaniae Longae: base is former: be the herb of menispermaceous plants Herba Stephaniae Longae or rhizome and root.Nature and flavor: micro-hardship, puckery are flat.Function cures mainly: heat-clearing and toxic substances removing, inducing diuresis to remove edema.For pyelonephritis, cystitis, chronic nephritis, enteritis, dysentery, venom; Carbuncle furuncle infections is controlled in external, suppurative otitis media.
Herba Lanceae Tibeticae: base is former: be the herb of goatweed Fructus Lanceae tibeticae.Nature and flavor: sweet in the mouth; Bitter; Cold in nature.Function cures mainly: lung heat clearing; Evacuation of pus; Removing toxic substances; Detumescence.Main cough due to lung-heat; Lung abscess; Influenza; Dysentery; Laryngopharynx swelling and pain.
Semen Plantaginis: base is former: be the seed of Plantaginaceae plant Herba Plantaginis or Plantago depressa Willd.Chemical analysis: containing volume phlegmatic temperament, aucubin, and containing plantenolic acid, choline, adenine, succinic acid, resin etc.Nature and flavor: sweet, cold.Gui Jing: enter kidney, urinary bladder channel.Function cures mainly: diuretic, heat clearing away, tomorrow, eliminates the phlegm.Control urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, heat-damp in summer dysentery, cough ant phlegm, arthralgia chiefly caused by damp pathogen, conjunctival congestion is hidden from view.
The pharmaceutical formulation science for the treatment of constipation provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, therapeutic effect is good, and cure rate is high, effectively can reduce relapse rate;
2, this formula is summed up through clinical practice for many years and is formed, and has effect of loosening bowel to relieve constipation, invigorating the spleen and benefiting QI;
3, Chinese crude drug selected by the present invention, safety has no side effect, can long-term taking, regulates patient body function.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the preparation for the treatment of constipation, is prepared from (every part of 10g) primarily of following bulk drugs: Semen Pruni 10 parts, Folium Hoveniae 8 parts, Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) 10 parts, Fructus Perillae 9 parts, Fructus Cannabis 6 parts, Fructus Forsythiae 11 parts, Herba Salsolae Collinae 9 parts, Radix Angelicae Sinensis 12 parts, Semen Cassiae Occidemtalis 8 parts, Fructus Pruni Tomentosae 7 parts, Folium Rumicis Japonici 6 parts, Herba Morindae Parvifoliae 9 parts, Herba Cistanches 10 parts, Herba Stephaniae Longae 8 parts, Herba Lanceae Tibeticae 9 parts, Semen Plantaginis 7 parts.The preparation method of the preparation soft extract of above-mentioned treatment constipation is:
(1) get Semen Pruni, Fructus Cannabis, Fructus Forsythiae, Semen Cassiae Occidemtalis and Semen Plantaginis remove impurity to clean, be placed in pot, drench into oil, big fire stir-fries 7 minutes, and take out, pulverize, add salt water infiltration 15 minutes, slow fire dries, and takes out;
(2) get Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.), Fructus Perillae and Fructus Pruni Tomentosae to clean, add rice wine and boil to well-done, take out and be placed in baking box, 110 DEG C of constant temperature toast 18 minutes, take out and pulverize together with step (1) made crude drug;
(3) Folium Hoveniae and Folium Rumicis Japonici are cleaned chopping, add rice vinegar and mix thoroughly, moistening 20 minutes, take out, put into frying pan, moderate heat is fried to surperficial zoom, takes out;
(4) Herba Salsolae Collinae, Radix Angelicae Sinensis, Herba Morindae Parvifoliae, Herba Cistanches, Herba Stephaniae Longae and Herba Lanceae Tibeticae are cleaned remove impurity, be placed in marmite, add the water of boiled crude drug quality 6 times, intense fire is heated to boiling, then adds step (3) made crude drug, turns little fire and decocts 22 minutes, after filtration, collect filtrate;
(5) blend step (2) (4) gained medicated powder and filtrate, heating is concentrated into thick paste, obtains soft extract.
embodiment 2the preparation for the treatment of constipation, is prepared from (every part of 10g) primarily of following bulk drugs: Semen Pruni 17 parts, Folium Hoveniae 16 parts, Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) 16 parts, Fructus Perillae 14 parts, Fructus Cannabis 12 parts, Fructus Forsythiae 17 parts, Herba Salsolae Collinae 16 parts, Radix Angelicae Sinensis 18 parts, Semen Cassiae Occidemtalis 13 parts, Fructus Pruni Tomentosae 14 parts, Folium Rumicis Japonici 11 parts, Herba Morindae Parvifoliae 12 parts, Herba Cistanches 15 parts, Herba Stephaniae Longae 12 parts, Herba Lanceae Tibeticae 15 parts, Semen Plantaginis 16 parts.The preparation method of the preparation powder of above-mentioned treatment constipation is:
(1) get Semen Pruni, Fructus Cannabis, Fructus Forsythiae, Semen Cassiae Occidemtalis and Semen Plantaginis remove impurity to clean, be placed in pot, drench into oil, big fire stir-fries 7 minutes, and take out, pulverize, add salt water infiltration 15 minutes, slow fire dries, and takes out;
(2) get Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.), Fructus Perillae and Fructus Pruni Tomentosae to clean, add rice wine and boil to well-done, take out and be placed in baking box, 110 DEG C of constant temperature toast 18 minutes, take out;
(3) Folium Hoveniae and Folium Rumicis Japonici are cleaned chopping, add rice vinegar and mix thoroughly, moistening 20 minutes, take out, put into frying pan, moderate heat is fried to surperficial zoom, takes out;
(4) Herba Salsolae Collinae, Radix Angelicae Sinensis, Herba Morindae Parvifoliae, Herba Cistanches, Herba Stephaniae Longae and Herba Lanceae Tibeticae are cleaned remove impurity, be placed in marmite, add the water of boiled crude drug quality 6 times, intense fire is heated to boiling, then adds step (3) made crude drug, turns little fire and decocts 22 minutes, after filtration, collect filtrate;
(5) heat concentration step (4) gained filtrate, pulverized 180 mesh sieves after drying together with step (1) (2) made crude drug, and obtained powder.
Model case: xxx, male, 24 years old.Medical history: suffer from constipation 2 years, stool has some setbacks, difficult defecation, average four days defecations 1-2 time, and just have the uncomfortable diseases such as stomachache, insomnia, anxiety, during one's sickness, once took cathartic treatment, constipation symptom slightly takes a turn for the better, but after drug withdrawal, disease relapse, patient is very painful.
Recommending to take this example gained powder, each 2-3g, warm boiled water, one day twice through people, ten days is a course for the treatment of, patient takes a course for the treatment of, and times of defecation increases, and defecation is comparatively smooth and easy, after adhering to two courses for the treatment of of use, tients with constipation's symptom is eliminated, and recovery from illness, follow up a case by regular visits to after 1 year, patient is not recurred.
embodiment 3the preparation for the treatment of constipation, is prepared from (every part of 10g) primarily of following bulk drugs: Semen Pruni 12 parts, Folium Hoveniae 10 parts, Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) 11 parts, Fructus Perillae 10 parts, Fructus Cannabis 8 parts, Fructus Forsythiae 13 parts, Herba Salsolae Collinae 11 parts, Radix Angelicae Sinensis 14 parts, Semen Cassiae Occidemtalis 9 parts, Fructus Pruni Tomentosae 9 parts, Folium Rumicis Japonici 7 parts, Herba Morindae Parvifoliae 10 parts, Herba Cistanches 11 parts, Herba Stephaniae Longae 9 parts, Herba Lanceae Tibeticae 11 parts, Semen Plantaginis 9 parts.The preparation method of the preparation decoction of above-mentioned treatment constipation is:
(1) get Semen Pruni, Fructus Cannabis, Fructus Forsythiae, Semen Cassiae Occidemtalis and Semen Plantaginis remove impurity to clean, be placed in pot, drench into oil, big fire stir-fries 7 minutes, and take out, pulverize, add salt water infiltration 15 minutes, slow fire dries, and takes out;
(2) get Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.), Fructus Perillae and Fructus Pruni Tomentosae to clean, add rice wine and boil to well-done, take out and be placed in baking box, 110 DEG C of constant temperature toast 18 minutes, take out and pulverize together with step (1) made crude drug;
(3) Folium Hoveniae and Folium Rumicis Japonici are cleaned chopping, add rice vinegar and mix thoroughly, moistening 20 minutes, take out, put into frying pan, moderate heat is fried to surperficial zoom, takes out;
(4) Herba Salsolae Collinae, Radix Angelicae Sinensis, Herba Morindae Parvifoliae, Herba Cistanches, Herba Stephaniae Longae and Herba Lanceae Tibeticae are cleaned remove impurity, be placed in marmite, add the soak by water of boiled crude drug quality 7.5 times, intense fire is heated to boiling, then adds step (3) made crude drug, turns little fire and decocts 22 minutes, after filtration, collect filtrate;
(5) blend step (2) (4) made medicated powder and filtrate, heating is concentrated into the half of original volume, obtains decoction.
Model case: xxx, women, 44 years old.Main suit: suffer from abdominal pain weak, difficult defecation, did not defecate in four days; Medical history: patient closely in two years, often occur stomachache phenomenon, continue 1-3 minute, defecate dry and astringent, be afraid of cold, easy to be tired out weak, checks, patient's xerostomia, pale tongue through doctor by fear of cold, and thin fur is slightly yellow, and deep and weak pulse, is diagnosed as chronic constipation.
By the agency of takes this example gained decoction, each 200-300ml, warmly takes, one day twice ten days is a course for the treatment of, after patient takes three days, colic symptoms disappears substantially, defecation 3 times, after taking a course for the treatment of, stool deliquescing, defecation is no longer difficult, after consolidating a course for the treatment of, patient fully recovers, stool is normal, follows up a case by regular visits in half a year, has no recurrence.
embodiment 4the preparation for the treatment of constipation, is prepared from (every part of 10g) primarily of following bulk drugs: Semen Pruni 15 parts, Folium Hoveniae 14 parts, Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) 15 parts, Fructus Perillae 13 parts, Fructus Cannabis 10 parts, Fructus Forsythiae 15 parts, Herba Salsolae Collinae 14 parts, Radix Angelicae Sinensis 16 parts, Semen Cassiae Occidemtalis 12 parts, Fructus Pruni Tomentosae 12 parts, Folium Rumicis Japonici 10 parts, Herba Morindae Parvifoliae 11 parts, Herba Cistanches 14 parts, Herba Stephaniae Longae 11 parts, Herba Lanceae Tibeticae 13 parts, Semen Plantaginis 14 parts.The preparation method of the preparation pill of above-mentioned treatment constipation is:
(1) get Semen Pruni, Fructus Cannabis, Fructus Forsythiae, Semen Cassiae Occidemtalis and Semen Plantaginis remove impurity to clean, be placed in pot, drench into oil, big fire stir-fries 7 minutes, and take out, pulverize, add salt water infiltration 15 minutes, slow fire dries, and takes out;
(2) get Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.), Fructus Perillae and Fructus Pruni Tomentosae to clean, add rice wine and boil to well-done, take out and be placed in baking box, 110 DEG C of constant temperature toast 18 minutes, take out;
(3) Folium Hoveniae and Folium Rumicis Japonici are cleaned chopping, add rice vinegar and mix thoroughly, moistening 20 minutes, take out, put into frying pan, moderate heat is fried to surperficial zoom, takes out;
(4) Herba Salsolae Collinae, Radix Angelicae Sinensis, Herba Morindae Parvifoliae, Herba Cistanches, Herba Stephaniae Longae and Herba Lanceae Tibeticae are cleaned remove impurity, be placed in marmite, add the water of boiled crude drug quality 6 times, intense fire is heated to boiling, then adds step (3) made crude drug, turns little fire and decocts 22 minutes, after filtration, collect filtrate;
(5) spray drying step (4) gained filtrate, pulverized 100 mesh sieves by dry thing, added refined honey water together with step (1) (2) made crude drug, generally made ball, dry packing, obtained pill.
Model case: xxx, male, 58 years old.Main suit: suffer from constipation 6 years, once, awareness of defecation is not obvious, comparatively requires great effort during defecation for every three days defecations, and having row to feel not to the utmost, constipation with dry stool is comparatively hard, suffers from abdominal pain without obvious abdominal distention, intermittent dependence cathartic defecation, to examination in hospital, fecal occult blood, has polyp of colon, is diagnosed as chronic constipation.
Accept doctor advised, use traditional Chinese medical science expectant treatment, take this example gained pill, each 2-3 grain, warm boiled water, one day twice, within ten days, be a course for the treatment of, after patient takes a course for the treatment of, defecation frequency obviously increases, stool deliquescing, health obviously recovers, after adhering to taking two courses for the treatment of, patient's defecation is normal, feel not to the utmost without row, follow up a case by regular visits to after 1 year, the state of an illness does not recur.
embodiment 5the preparation for the treatment of constipation, is prepared from (every part of 10g) primarily of following bulk drugs: Semen Pruni 13.5 parts, Folium Hoveniae 12 parts, Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) 13 parts, Fructus Perillae 11.5 parts, Fructus Cannabis 9 parts, Fructus Forsythiae 14 parts, Herba Salsolae Collinae 12.5 parts, Radix Angelicae Sinensis 15 parts, Semen Cassiae Occidemtalis 10.5 parts, Fructus Pruni Tomentosae 10.5 parts, Folium Rumicis Japonici 8.5 parts, Herba Morindae Parvifoliae 10.5 parts, Herba Cistanches 12.5 parts, Herba Stephaniae Longae 10 parts, Herba Lanceae Tibeticae 12 parts, Semen Plantaginis 11.5 parts.The preparation method of the preparation soft extract of above-mentioned treatment constipation is:
(1) get Semen Pruni, Fructus Cannabis, Fructus Forsythiae, Semen Cassiae Occidemtalis and Semen Plantaginis remove impurity to clean, be placed in pot, drench into oil, big fire stir-fries 7 minutes, and take out, pulverize, add salt water infiltration 15 minutes, slow fire dries, and takes out;
(2) get Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.), Fructus Perillae and Fructus Pruni Tomentosae to clean, add rice wine and boil to well-done, take out and be placed in baking box, 110 DEG C of constant temperature toast 18 minutes, take out and pulverize together with step (1) made crude drug;
(3) Folium Hoveniae and Folium Rumicis Japonici are cleaned chopping, add rice vinegar and mix thoroughly, moistening 20 minutes, take out, put into frying pan, moderate heat is fried to surperficial zoom, takes out;
(4) Herba Salsolae Collinae, Radix Angelicae Sinensis, Herba Morindae Parvifoliae, Herba Cistanches, Herba Stephaniae Longae and Herba Lanceae Tibeticae are cleaned remove impurity, be placed in marmite, add the water of boiled crude drug quality 6 times, intense fire is heated to boiling, then adds step (3) made crude drug, turns little fire and decocts 22 minutes, after filtration, collect filtrate;
(5) blend step (2) (4) gained medicated powder and filtrate, heating is concentrated into thick paste, obtains soft extract.
test example 1the clinical practice of the preparation (embodiment 5) of gained treatment constipation of the present invention:
Choose crowd: in April ,-2015 in February, 2014, according to medical case history, have patient 268 example of constipation symptom six hospitals' screenings, age 18-64 year, 38.5 ± 2.2 years old mean age, course of disease 0.5-25, wherein male patient 132 example, female patient 136 example.All cases weekly defecation are less than 3 times, and excrement matter is hard or difficult defecation.Get rid of the diseases such as digestive tract organic disease, diabetes, hypothyroidism on inspection.
Before test, patient is divided into two groups at random, experimental group 183 example and matched group 85 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes products obtained therefrom of the present invention, each 4-6g, one day twice, warm boiled water, within ten days, is a course for the treatment of; Matched group takes other conventional medicines (MAREN RUNCHANG WAN, aloe capsule, TONGBIAN LING etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: in two weeks, times of defecation is more than 6 times, and defecation is smooth and easy, and stool deliquescing, without other uncomfortable diseases; (2) effective: in two weeks, times of defecation is 3-6 time, and defecation is slightly required great effort, and defecates harder; (3) invalid: before and after treatment, symptom is without improving or increasing the weight of.
Clinical effectiveness: after the taking medicine of two courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
As shown in Table 1, experimental group total effective rate be 98.4%, apparently higher than the total effective rate of matched group, illustrate that products obtained therefrom of the present invention is evident in efficacy, cure rate is high.After half a year, follow up a case by regular visits to two groups of patients, experimental group only has an example recurrence, and matched group patients with recurrent reaches 10 examples, products obtained therefrom treating both the principal and secondary aspects of a disease of the present invention is described, effectively prevents the state of an illness from again recurring.
The Chinese medicine used in the present invention, Semen Pruni, Herba Salsolae Collinae can loosening bowel to relieve constipation, Folium Hoveniae can heat-clearing and toxic substances removing, the feasible water of Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) can just, and Fructus Perillae is relievingd asthma intestine moistening, and Fructus Cannabis can moisturize laxation, Fructus Forsythiae can dispersing swelling and dissipating binds, Radix Angelicae Sinensis can be enriched blood and be invigorated blood circulation, and Semen Cassiae Occidemtalis relieving constipation is detoxified, and Fructus Pruni Tomentosae can invigorating the spleen and benefiting QI, Folium Rumicis Japonici can cooling blood for hemostasis, Herba Morindae Parvifoliae can stomach function regulating removing dampness, and Herba Cistanches can intestine moistening road, and Herba Stephaniae Longae can inducing diuresis to remove edema, Herba Lanceae Tibeticae removing toxic substances and promoting subsidence of swelling, Semen Plantaginis can diuretic heat clearing away, and multiple medical material synergism, plays effect of loosening bowel to relieve constipation, invigorating the spleen and benefiting QI altogether.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat the preparation of constipation, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Semen Pruni 10-17; Folium Hoveniae 8-16; Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) 10-16; Fructus Perillae 9-14; Fructus Cannabis 6-12; Fructus Forsythiae 11-17; Herba Salsolae Collinae 9-16; Radix Angelicae Sinensis 12-18; Semen Cassiae Occidemtalis 8-13; Fructus Pruni Tomentosae 7-14; Folium Rumicis Japonici 6-11; Herba Morindae Parvifoliae 9-12; Herba Cistanches 10-15; Herba Stephaniae Longae 8-12; Herba Lanceae Tibeticae 9-15; Semen Plantaginis 7-16.
2. the preparation for the treatment of constipation as claimed in claim 1, is characterized in that, Semen Pruni 12-15; Folium Hoveniae 10-14; Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) 11-15; Fructus Perillae 10-13; Fructus Cannabis 8-10; Fructus Forsythiae 13-15; Herba Salsolae Collinae 11-14; Radix Angelicae Sinensis 14-16; Semen Cassiae Occidemtalis 9-12; Fructus Pruni Tomentosae 9-12; Folium Rumicis Japonici 7-10; Herba Morindae Parvifoliae 10-11; Herba Cistanches 11-14; Herba Stephaniae Longae 9-11; Herba Lanceae Tibeticae 11-13; Semen Plantaginis 9-14(is preferably: Semen Pruni 13.5; Folium Hoveniae 12; Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) 13; Fructus Perillae 11.5; Fructus Cannabis 9; Fructus Forsythiae 14; Herba Salsolae Collinae 12.5; Radix Angelicae Sinensis 15; Semen Cassiae Occidemtalis 10.5; Fructus Pruni Tomentosae 10.5; Folium Rumicis Japonici 8.5; Herba Morindae Parvifoliae 10.5; Herba Cistanches 12.5; Herba Stephaniae Longae 10; Herba Lanceae Tibeticae 12; Semen Plantaginis 11.5).
3. the preparation of the treatment constipation as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable soft extract, its preparation method is:
(1) get Semen Pruni, Fructus Cannabis, Fructus Forsythiae, Semen Cassiae Occidemtalis and Semen Plantaginis remove impurity to clean, be placed in pot, drench into oil, big fire stir-fry 4-10 minute (preferred: big fire stir-fries 6-8 minute; Be more preferably: big fire stir-fries 7 minutes), take out, pulverize, add salt water infiltration 15 minutes, slow fire dries, and takes out;
(2) get Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.), Fructus Perillae and Fructus Pruni Tomentosae to clean, add rice wine and boil to well-done, take out and be placed in baking box, 110 DEG C of constant temperature toast 12-24 minute (preferably: constant temperature baking 16-20 minute; Be more preferably: constant temperature toasts 18 minutes), take out and pulverize together with step (1) made crude drug;
(3) Folium Hoveniae and Folium Rumicis Japonici are cleaned chopping, add rice vinegar and mix thoroughly, moistening 16-24 minute (preferred: moistening 18-22 minute; Be more preferably: moistening 20 minutes), take out, put into frying pan, moderate heat is fried to surperficial zoom, takes out;
(4) Herba Salsolae Collinae, Radix Angelicae Sinensis, Herba Morindae Parvifoliae, Herba Cistanches, Herba Stephaniae Longae and Herba Lanceae Tibeticae are cleaned remove impurity, be placed in marmite, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times), intense fire is heated to boiling, add step (3) made crude drug again, turn little fire to decoct, after filtration, collect filtrate;
(5) blend step (2) (4) gained medicated powder and filtrate, heating is concentrated into thick paste, obtains soft extract.
4. the preparation method of the preparation soft extract for the treatment of constipation as claimed in claim 3, is characterized in that, it is (preferred: to turn little fire and decoct 20-24 minute that step (4) turns little fire decoction 18-26 minute; Be more preferably: turn little fire and decoct 22 minutes).
5. the preparation of the treatment constipation as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Semen Pruni, Fructus Cannabis, Fructus Forsythiae, Semen Cassiae Occidemtalis and Semen Plantaginis remove impurity to clean, be placed in pot, drench into oil, big fire stir-fry 4-10 minute (preferred: big fire stir-fries 6-8 minute; Be more preferably: big fire stir-fries 7 minutes), take out, pulverize, add salt water infiltration 15 minutes, slow fire dries, and takes out;
(2) get Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.), Fructus Perillae and Fructus Pruni Tomentosae to clean, add rice wine and boil to well-done, take out and be placed in baking box, 110 DEG C of constant temperature toast 12-24 minute (preferably: constant temperature baking 16-20 minute; Be more preferably: constant temperature toasts 18 minutes), take out;
(3) Folium Hoveniae and Folium Rumicis Japonici are cleaned chopping, add rice vinegar and mix thoroughly, moistening 16-24 minute (preferred: moistening 18-22 minute; Be more preferably: moistening 20 minutes), take out, put into frying pan, moderate heat is fried to surperficial zoom, takes out;
(4) Herba Salsolae Collinae, Radix Angelicae Sinensis, Herba Morindae Parvifoliae, Herba Cistanches, Herba Stephaniae Longae and Herba Lanceae Tibeticae are cleaned remove impurity, be placed in marmite, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times), intense fire is heated to boiling, add step (3) made crude drug again, turn little fire and decoct 18-26 minute (preferably: turn little fire and decoct 20-24 minute; Be more preferably: turn little fire and decoct 22 minutes), after filtration, collect filtrate;
(5) heat concentration step (4) gained filtrate, pulverize and sieve together with step (1) (2) made crude drug after drying, obtain powder.
6. the preparation method of the preparation powder for the treatment of constipation as claimed in claim 5, it is characterized in that, it is (preferred: to pulverize 160-200 mesh sieve that step (5) pulverized 130-230 mesh sieve; Be more preferably: pulverized 180 mesh sieves).
7. the preparation of the treatment constipation as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Semen Pruni, Fructus Cannabis, Fructus Forsythiae, Semen Cassiae Occidemtalis and Semen Plantaginis remove impurity to clean, be placed in pot, drench into oil, big fire stir-fry 4-10 minute (preferred: big fire stir-fries 6-8 minute; Be more preferably: big fire stir-fries 7 minutes), take out, pulverize, add salt water infiltration 15 minutes, slow fire dries, and takes out;
(2) get Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.), Fructus Perillae and Fructus Pruni Tomentosae to clean, add rice wine and boil to well-done, take out and be placed in baking box, 110 DEG C of constant temperature toast 12-24 minute (preferably: constant temperature baking 16-20 minute; Be more preferably: constant temperature toasts 18 minutes), take out and pulverize together with step (1) made crude drug;
(3) Folium Hoveniae and Folium Rumicis Japonici are cleaned chopping, add rice vinegar and mix thoroughly, moistening 16-24 minute (preferred: moistening 18-22 minute; Be more preferably: moistening 20 minutes), take out, put into frying pan, moderate heat is fried to surperficial zoom, takes out;
(4) Herba Salsolae Collinae, Radix Angelicae Sinensis, Herba Morindae Parvifoliae, Herba Cistanches, Herba Stephaniae Longae and Herba Lanceae Tibeticae are cleaned remove impurity, be placed in marmite, decoct with water, intense fire is heated to boiling, add step (3) made crude drug again, turn little fire and decoct 18-26 minute (preferably: turn little fire and decoct 20-24 minute; Be more preferably: turn little fire and decoct 22 minutes), after filtration, collect filtrate;
(5) blend step (2) (4) made medicated powder and filtrate, heating is concentrated into the half of original volume, obtains decoction.
8. the preparation method of the preparation decoction for the treatment of constipation as claimed in claim 7, is characterized in that, the 6-9 that step (4) amount of water is boiled crude drug quality is doubly (preferred: the 7-8 that amount of water is boiled crude drug quality doubly; Be more preferably: amount of water is 7.5 times of boiled crude drug quality).
9. the preparation of the treatment constipation as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get Semen Pruni, Fructus Cannabis, Fructus Forsythiae, Semen Cassiae Occidemtalis and Semen Plantaginis remove impurity to clean, be placed in pot, drench into oil, big fire stir-fry 4-10 minute (preferred: big fire stir-fries 6-8 minute; Be more preferably: big fire stir-fries 7 minutes), take out, pulverize, add salt water infiltration 15 minutes, slow fire dries, and takes out;
(2) get Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.), Fructus Perillae and Fructus Pruni Tomentosae to clean, add rice wine and boil to well-done, take out and be placed in baking box, 110 DEG C of constant temperature toast 12-24 minute (preferably: constant temperature baking 16-20 minute; Be more preferably: constant temperature toasts 18 minutes), take out;
(3) Folium Hoveniae and Folium Rumicis Japonici are cleaned chopping, add rice vinegar and mix thoroughly, moistening 16-24 minute (preferred: moistening 18-22 minute; Be more preferably: moistening 20 minutes), take out, put into frying pan, moderate heat is fried to surperficial zoom, takes out;
(4) Herba Salsolae Collinae, Radix Angelicae Sinensis, Herba Morindae Parvifoliae, Herba Cistanches, Herba Stephaniae Longae and Herba Lanceae Tibeticae are cleaned remove impurity, be placed in marmite, add boiled crude drug quality 5-7 water doubly (preferred: the water adding boiled crude drug quality 6 times), intense fire is heated to boiling, add step (3) made crude drug again, turn little fire and decoct 18-26 minute (preferably: turn little fire and decoct 20-24 minute; Be more preferably: turn little fire and decoct 22 minutes), after filtration, collect filtrate;
(5) spray drying step (4) gained filtrate, pulverizes and sieves dry thing, adds refined honey water together with step (1) (2) made crude drug, generally makes ball, dry packing, obtains pill.
10. the preparation method of the preparation pill for the treatment of constipation as claimed in claim 9, it is characterized in that, it is (preferred: to pulverize 90-110 mesh sieve that step (5) pulverized 80-120 mesh sieve; Be more preferably: pulverized 100 mesh sieves).
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| CN101306179A (en) * | 2008-06-27 | 2008-11-19 | 张来祥 | Zimi ointment for emaciating body |
| CN103599358A (en) * | 2013-10-10 | 2014-02-26 | 陈友望 | Anti-constipation herbal tea formula |
| CN104258045A (en) * | 2014-09-25 | 2015-01-07 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicine for relaxing bowels and preparation method of traditional Chinese medicine |
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2015
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101306179A (en) * | 2008-06-27 | 2008-11-19 | 张来祥 | Zimi ointment for emaciating body |
| CN103599358A (en) * | 2013-10-10 | 2014-02-26 | 陈友望 | Anti-constipation herbal tea formula |
| CN104258045A (en) * | 2014-09-25 | 2015-01-07 | 苏州市天灵中药饮片有限公司 | Traditional Chinese medicine for relaxing bowels and preparation method of traditional Chinese medicine |
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