CN105616576A

CN105616576A - Blood-activating and dysentery-stopping thick paste for chronic dysentery

Info

Publication number: CN105616576A
Application number: CN201610095588.2A
Authority: CN
Inventors: 不公告发明人
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-10-28
Filing date: 2014-10-28
Publication date: 2016-06-01
Also published as: CN104367650A; CN105687362A; CN105560430A

Abstract

The invention discloses blood-activating and dysentery-stopping thick paste for chronic dysentery.The thick paste is prepared from, by weight, 3-6 parts of rhizoma coptidis, 10-20 parts of radix pulsatillae, 5-15 parts of radix aucklandiae, 15-25 parts of capitate knotweed herb, 6-12 parts of twigs and leaves of java bishopwood, 12-20 parts of milkvetch roots, 6-10 parts of radix angelicae sinensis, 8-15 parts of cassia twigs, 18-40 parts of herba portulacae, 6-12 parts of rhizoma chuanxiong, 6-15 parts of roots of sampsonii hance and 4-9 parts of herb of abacopteris simplex (Hook.) ching.The preparation is significant in curative effect, free of toxic and side effects, short in course of treatment, quick in effect and free of relapse.

Description

Chronic dysentery is invigorated blood circulation dysentery relieving thick paste

Divisional application, original applying number 2014105830371, applying date 2014.10.28, title chronic dysentery is invigorated blood circulation dysentery stopping preparation and preparation method.

Technical field

The present invention relates to traditional Chinese medicine field, particularly relate to a kind of chronic dysentery and invigorate blood circulation dysentery stopping preparation and preparation method thereof.

Background technology

Dysentery is a kind of commonly encountered diseases being main feature with stomachache, tenesmus, dysentery pus and blood, is apt to occur in summer and autumn. "Nei Jing" is referred to as " spouting bleeding from anus ", " red fertile ", caused by the heresy how damp and hot by impression, epidemic disease is malicious and eating and drinking without temperance impairing the spleen and stomach intestinal internal organs. The course of disease is called chronic dysentery more than more than two months persons. How being changed by acute bacillary dysentery, with good fortune, Salmonella the infected is in the majority. Some courses of disease are several months or several years, and intestinal pathological changes is risen one after another during this period, and original ulcer not yet heals, and new ulcer is formed again. Therefore new and old focus exists simultaneously. Due to tissue injury repairing be repeatedly performed, chronic ulcer edge is irregular, the normal hyperplasia of mucosa and form polyp. Or even each layer of intestinal wall has chronic inflammatory cell infiltration and proliferation of fibrous tissue cicatrization, so that intestinal wall irregular thickening, hardening, serious case can cause stenosis of bowel.

The treatment of chronic dysentery: 1. general treatment. Form good living habit, it is to avoid psychentonia, note striking a proper balance between work and rest, improve resistance and the adaptive faculty of body. The few slag of feed, nutritious, be prone to the food of digestion, it is to avoid cold stimulation, active treatment intestinal parasitical diseases. 2. Drug therapy. Effective antibacterials are selected according to drug sensitive test result or conventional Couple herbs, 2 kinds of antibacterials of use in conjunction also extend the period for the treatment of to 10��15 days, also can the effective antibacterials of alternate application, retention enema can be carried out if desired: enema 200mL, add antibacterials such as 0.5% kanamycin, 1%��2% neomycin etc. with 0.25% procaine and 20mg prednisone, every night once, within 10��14 days, be a course for the treatment of. The traditional Chinese medical science thinks that the treatment to deficiency of YIN dysentery is that consolidating YIN expels the heat-evil, righting dysentery relieving. Zhuche pills plus-minus is closed with Chinese goldthread colla corii asini decoction. Chronic dysentery with frequent relapse is damp and hot based on Qinghua when showing effect, available Radix Pulsatillae Decoction plus-minus. Based on invigorating the spleen and benefiting QI when stopping, available invigorating the spleen and regulating the stomach soup closes Xianglian Wan. Deficiency and coldness dysentery is answered warming and recuperating the spleen and kidney, and assistant is admittedly to take off. Subtract with Taohua Tang He Yangzang Tonga. Answer clearing away heat and eliminating dampness to detoxify dysentery due to damp-heat, be aided with regulating QI promoting the circulation of blood. Fulminant dysentery is answered clearing away heat,cooling blood and removing toxin.

Publication number CN1857460A(application number 2006100050998.1) Chinese patent literature disclose a kind of pharmaceutical composition treating dysentery, Main Ingredients and Appearance is herb Potentillae cryptotaeniae, Radix ardisiae villosae, Fructus glochidionis puberi(Herba Glochidii Puberi), Herba Chenopodii Hybridi, Folium Bauhiniae pernervosae, Mahonia fortunei (Lindl.) Fedde and Mel. Application publication number CN104096159A(application number 201410343777.8) Chinese patent literature disclose a kind of viable bacteria mixture alleviating chronic dysentery and bowel dysfunction, take off the primary raw material stating weight proportion to be prepared from: Fructus Evodiae 2-4 part, Fructus Gardeniae 3-10 part, Massa Medicata Fermentata 4-12 part, Fructus Schisandrae Chinensis 5-12 part, Poria cum Radix Pini's 4-12 part, Fructus Crataegi 6-15 part, Herba Dendrobii 6-9 part, Fructus Amomi 5-12 part, Nodus Nelumbinis Rhizomatis 3-10 part, bacillus cereus 0.3-1.0 part. Application publication number CN103405703A(application number 201310275325.6) Chinese patent literature provide a kind of Chinese medicine pill treating chronic dysentery, become Chinese medicine component including following weight ratio thin,tough silk: Radix Scutellariae 10-15 part, Rhizoma Atractylodis Macrocephalae 12-18 part, 15 parts of Poria, Massa Medicata Fermentata 5 parts, the Radix Aucklandiae 8 parts, Fructus Amomi 10-15 part, Rhizoma Dioscoreae 15-20 part, 10 parts of Flos Sophorae, Radix Platycodonis 5 parts, difficult to understand Cortex Ailanthi 20 parts, Radix Sanguisorbae 10-15 part, Herba Portulacae 20 parts, 6 parts of Radix Glycyrrhizae; The preparation method additionally providing pill.

In a word, the chronic bacillary dysentery course of disease is long, recurrent exerbation or protracted course of disease, and clinical in antibiotic therapy at present, bad for chronic dysentery curative effect, toxic and side effects is big. And treatment by Chinese herbs chronic dysentery is longer for the course for the treatment of.

Summary of the invention

For the deficiencies in the prior art, it is an object of the invention to provide a kind of chronic dysentery and invigorate blood circulation dysentery stopping preparation and preparation method thereof. Said preparation is evident in efficacy, have no side effect, short treating period, instant effect, without recurrence.

The technical scheme is that

Chronic dysentery is invigorated blood circulation dysentery stopping preparation, takes off the primary raw material medicine stating weight proportion and is prepared from: Rhizoma Coptidis 3-6, Radix Pulsatillae 10-20, Radix Aucklandiae 5-15, Herba Polygoni Capitati 15-25, Ramulus et Folium Bischofiae Javanicae 6-12, Radix Astragali 12-20, Radix Angelicae Sinensis 6-10, Ramulus Cinnamomi 8-15, Herba Portulacae 18-40, Rhizoma Chuanxiong 6-12, Radix Thyrocarpi sampsonii 6-15, straw sandals green grass or young crops 4-9.

Chronic dysentery is invigorated blood circulation dysentery stopping preparation, it is preferred that scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Rhizoma Coptidis 4-5.5, Radix Pulsatillae 13-16, Radix Aucklandiae 8-12, Herba Polygoni Capitati 19-22, Ramulus et Folium Bischofiae Javanicae 8-11, Radix Astragali 15-18, Radix Angelicae Sinensis 7-9, Ramulus Cinnamomi 11-13, Herba Portulacae 24-32, Rhizoma Chuanxiong 9-11, Radix Thyrocarpi sampsonii 8-11, straw sandals green grass or young crops 6-8.

Chronic dysentery is invigorated blood circulation dysentery stopping preparation, it is more preferable to scheme be take off the primary raw material medicine stating weight proportion and be prepared from: Rhizoma Coptidis 5, the Radix Pulsatillae 14, the Radix Aucklandiae 10, Herba Polygoni Capitati 21, Ramulus et Folium Bischofiae Javanicae 9, the Radix Astragali 17, Radix Angelicae Sinensis 8, Ramulus Cinnamomi 12, Herba Portulacae 29, Rhizoma Chuanxiong 10, Radix Thyrocarpi sampsonii 9, straw sandals green grass or young crops 7.

Present invention also offers the preparation method that dysentery stopping preparation of aforementioned chronic dysentery being invigorated blood circulation makes pharmaceutically acceptable decoction, powder, thick paste agent and pill.

The preparation method of described decoction is:

(1) Radix Pulsatillae is removed impurity, clean dust, be soaked in water 15-35 minute (being preferably soaked in water 25 minutes), drag in basket, add a cover wet cloth and moisten 4-8 hour (preferably adding a cover wet cloth to moisten 5 hours), take out, section, soak 1.5-3.5 hour (preferably soaking 2.5 hours with wine again) with wine again, take out;

(2) all the other the 10 taste crude drugs except the Radix Pulsatillae and the Radix Aucklandiae are placed in marmite, add water, the consumption of water is 2.5-5.5 times (consumption of preferred water is 4.5 times of medical material gross weight added) of the medical material gross weight added, and soaks 1.5-2.5 hour (preferred immersion 2 hours);

(3) medical material step (2) soaked first boils to boiling with big fire, rear turn of little fire decocts 15-30 minute (after preferably, a turn little fire decocts 22 minutes), add water, the consumption of water is 2.2-4.5 times 3.2 times of medical material gross weight of addition (consumption of preferred water be) of the medical material gross weight added, being subsequently adding the Radix Aucklandiae and step (1) the gained Radix Pulsatillae, boil to boiling with big fire, rear turn of little fire decocts 35-55 minute (after preferably, a turn little fire decocts 42 minutes), leach medicinal liquid, to obtain final product.

The preparation method of described powder is:

(1) Radix Pulsatillae is removed impurity, cleaning dust, be soaked in water 15-35 minute (being preferably soaked in water 25 minutes), drags in basket, add a cover wet cloth and moisten 4-8 hour (preferably adding a cover wet cloth to moisten 5 hours), take out, section, then soak 1.5-3.5 hour (preferably soaking 2.5 hours with wine again) with wine, take out, dry, be ground into fine powder, cross 130-170 mesh sieve (preferred mistake 150 mesh sieve);

(2) all the other crude drug except the Radix Pulsatillae being removed impurity, attrition grinding becomes fine powder respectively, crosses 140-180 mesh sieve (preferred mistake 150 mesh sieve);

(3) step (1) and step (2) gained fine powder are fully mixed, sterile packaged, often bag 5 grams.

The preparation method of described thick paste agent is:

(2) all the other the 10 taste crude drugs except the Radix Pulsatillae and the Radix Aucklandiae are placed in marmite, add water, the consumption of water is 2.2-5.5 times (consumption of preferred water is 4.5 times of medical material gross weight added) of the medical material gross weight added, and soaks 1.5-2.5 hour (preferred immersion 2 hours);

(3) medical material step (2) soaked first boils to boiling with big fire, rear turn of little fire decocts 15-30 minute (after preferably, a turn little fire decocts 22 minutes), add water, the consumption of water is 2.2-4.5 times 3.2 times of medical material gross weight of addition (consumption of preferred water be) of the medical material gross weight added, it is subsequently adding the Radix Aucklandiae and step (1) the gained Radix Pulsatillae, boiling to boiling with big fire, rear turn of little fire decocts 35-55 minute (after preferably, a turn little fire decocts 42 minutes), leaches medicinal liquid;

(4) being reduced pressure by step (3) gained medicinal liquid, being concentrated into relative density be the preferred relative density of 1.2-1.4(is 1.3) clear paste, be subsequently adding adjuvant and mix well, dress aseptic bottle seals and get final product.

The preparation method of described pill is:

(1) Radix Pulsatillae is removed impurity, cleaning dust, be soaked in water 15-35 minute (being preferably soaked in water 25 minutes), drags in basket, add a cover wet cloth and moisten 4-8 hour (preferably adding a cover wet cloth to moisten 5 hours), take out, section, then soak 1.5-3.5 hour (preferably soaking 2.5 hours with wine again) with wine, take out, dry, be ground into fine powder, cross 110-140 mesh sieve (preferred mistake 130 mesh sieve);

(2) all the other crude drug except the Radix Pulsatillae are removed impurity, after drying, these medicines are mixed together and are ground into fine powder, cross 110-150 mesh sieve (preferred mistake 130 mesh sieve), then fully mix with step (1) gained fine powder;

(3) refined honey is joined in step (2) gained mixing fine powder, the weight of refined honey is 0.9-1.8 times 1.3 times of medicine gross weight (weight of preferred refined honey be) of medicine gross weight, making little pill, the particle diameter of little pill is that to be preferably made the particle diameter of little pill be 3mm to 2-5mm().

The pharmacology of the present invention main raw material of Chinese medicine used is as follows:

Rhizoma Coptidis: another name: taste company, Rhizoma Coptidis, Rhizoma Coptidis, base: for the dry rhizome of ranunculaceae plant Rhizoma Coptidis, Coptis deltoidea C.Y.Cheng et Hsiao or Coptis Teeta Wall. The property of medicine: bitter, cold. GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel. Function cures mainly: heat clearing and damp drying, eliminating fire and detoxication. Tying mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted. Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting. For incoordination between the liver and stomach, vomit acid regurgitation.

The Radix Pulsatillae: base: this product is the dry root of the ranunculaceae plant Radix Pulsatillae. The property of medicine: bitter, cold. Return stomach, large intestine channel. Function cures mainly: heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery. For toxic-heat and blood stasis, pudendal pruritus leukorrhagia, amebic dysentery.

The Radix Aucklandiae: base: for the dry root of the feverfew Radix Aucklandiae. The property of medicine: pungent, bitter, temperature. Return spleen, stomach, large intestine, three burnt, gallbladder meridians. Function cures mainly: promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion. For breast gastral cavity distending pain, weight after dysentery, food stagnation does not disappear, anorexia. Radix Aucklandiae (roasted) reality intestinal antidiarrheal. For stomachache of having loose bowels.

Herba Polygoni Capitati: base: for the herb of polygonaceae plant Herba Polygoni Capitati. Chemical composition of Chinese materia medica: Herba Polygoni Capitati herb is containing benzaldehyde, acetic acid, 24-hydroxyl lignocerane-3-ketone, 29-hydroxyl nonacosane-3-ketone, cupreol, gallic acid. " Guangxi Chinese herbal medicine ": " bitter in the mouth, pungent, property is put down, nontoxic. " function cures mainly: removing toxic substances, dissipating blood stasis, inducing diuresis for treating stranguria syndrome. Control dysentery, pyelitis, cystitis, lithangiuria, rheumatalgia, traumatic injury, skin infection eczema.

Ramulus et Folium Bischofiae Javanicae: base: for the root of euphorbia plant Ramulus et Folium Bischofiae Javanicae, bark. Chemical composition of Chinese materia medica: stem is containing cupreol, freidelin, epifriedelanol, freidelin alcohol and cupreol-��-glycoside. Seed oil-containing 25.5%, the iodine number 159.0 of oil, saponification number 194.5. Fatty acid forms: myristic acid 0.3%, Palmic acid 10.5%, stearic acid 5.0%, hexadecenoic acid 0.2%, oleic acid 23.9%, linoleic acid 23.4%, linolenic acid 36.7%. The property of medicine: pungent, puckery, cool. GUIXIN warp. Function cures mainly: expelling wind and removing dampness, blood stasis dispelling removing food stagnancy. Main rheumatic ostalgia, dysphagic, regurgitation, dysentery.

The Radix Astragali: base: for the dry root of leguminous plant Radix Astagali or Radix Astragali. The property of medicine: sweet, temperature. Return lung, spleen channel. Function cures mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation. Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and bursts for a long time and does not hold back, and blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst, chronic nephritis proteinuria, diabetes.

Radix Angelicae Sinensis: base: for the dry root of umbelliferae angelica. The property of medicine: sweet, acrid, warm. Return liver, the heart, spleen channel. Function cures mainly: replenishing and activating blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation. For blood deficiency and yellow complexion, dizziness cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores. Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow. For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.

Ramulus Cinnamomi: base: for the twig of canella Cortex Cinnamomi. Ramulus Cinnamomi, containing volatile oil 0.69%, is mainly composed of cinnamic aldehyde 64.75% in oil, also have benzyl benzoate, cinnamyl acetate, ��-cadinene, Chang Pu's alkene, coumarin etc. The property of medicine: acrid, sweet, warm. Return bladder, the heart, lung meridian. Function cures mainly: expelling cold and relieving exterior syndrome, promoting the flow of QI-blood by warming the meridian. For activating YANG and prormoting functioning of QI exterior syndrome due to wind-cold, arthralgia due to cold-dampnes, extreme cold of the limbs, amenorrhea dysmenorrhea, abdominal mass is lumpd, the thoracic obstruction, cardiopalmus, phlegm retention, dysuria.

Herba Portulacae: base: for the herb of portulacaceous plant Herba Portulacae. Chemical composition of Chinese materia medica: herb is containing a large amount of norepinephrine and volume potassium salt (including potassium nitrate, potassium chloride, potassium sulfate and other potassium salt). Also containing DOPA, dopamine, betanidin, isobetanidin, different Radix Betae glycoside, oxalic acid, malic acid, citric acid, glutamic acid, aspartic acid, alanine and glucose, fructose, sucrose etc. The aobvious alkaloid of herb, coumarin, flavone, the reaction of cardiotonic glycoside and anthracene glycoside according to another report. And containing substantial amounts of poly-omega-3 unsaturated fatty acid. The property of medicine: acid, cold. Return large intestine, Liver Channel. Function cures mainly: heat-clearing and toxic substances removing, cooling blood for hemostasis. For toxic-heat and blood stasis, carbuncle furuncle, eczema, erysipelas, snake bite and insect sting, have blood in stool, hemorrhoidal bleeding, metrostaxis.

Rhizoma Chuanxiong: base: for the dry rhizome of samphire Rhizoma Chuanxiong. The property of medicine: pungent, temperature. Return liver, gallbladder, pericardium channel. Function cures mainly: blood-activating and qi-promoting, wind-expelling pain-stopping. For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, breast side of body twinge, tumbling and swelling, headache, rheumatic arthralgia.

Radix Thyrocarpi sampsonii: base: for the herb of Boraginaceae Radix Thyrocarpi sampsonii platymiscium Radix Thyrocarpi sampsonii. The property of medicine: bitter, cool. Function cures mainly: clearing heat, releasing toxin, removing swelling. Cure mainly carbuncle, furuncle, have sore throat, have loose bowels, dysentery.

Straw sandals are blue or green: base: for the herb of Thelypteridaceae Parathelypteris glanduligera (Kunze) Ching platymiscium Pronephrium simplex. The property of medicine: sweet, micro-puckery, cool. Function cures mainly: heat-clearing and toxic substances removing. Cure mainly laryngopharynx swelling and pain, dysentery, venom.

Chronic dysentery provided by the invention is invigorated blood circulation dysentery stopping preparation scientific formula, and the preparation method of various dosage forms is simple, products obtained therefrom taking convenience. In addition, the excellent results of the present invention is also manifested by:

1, safe and reliable, have no side effect;

2, short treating period, instant effect;

3, evident in efficacy, without recurrence;

4, there is effect of heat-clearing and toxic substances removing, loosening bowel to relieve constipation, dysentery relieving of invigorating blood circulation;

5, raw material is cheap and easy to get, and treatment cost is low, alleviates patient economy burden.

Detailed description of the invention

Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.

Embodiment 1 chronic dysentery is invigorated blood circulation dysentery stopping preparation, and the primary raw material medicine taking following weight is prepared from: Rhizoma Coptidis 3g, Radix Pulsatillae 10g, Radix Aucklandiae 5g, Herba Polygoni Capitati 15g, Ramulus et Folium Bischofiae Javanicae 6g, Radix Astragali 12g, Radix Angelicae Sinensis 6g, Ramulus Cinnamomi 8g, Herba Portulacae 18g, Rhizoma Chuanxiong 6g, Radix Thyrocarpi sampsonii 6g, straw sandals green grass or young crops 4g.

The invigorate blood circulation preparation method of dysentery stopping preparation decoction of chronic dysentery is:

(1) Radix Pulsatillae is removed impurity, clean dust, be soaked in water 15 minutes, drag in basket, add a cover wet cloth and moisten 4 hours, take out, section, then soak 1.5 hours with wine, take out;

(2) being placed in marmite by all the other the 10 taste crude drugs except the Radix Pulsatillae and the Radix Aucklandiae, add water, the consumption of water is 2.5 times of the medical material gross weight added, soaks 2 hours;

(3) medical material step (2) soaked first boils to boiling with big fire, rear turn of little fire decocts 15 minutes, add water, the consumption of water is 2.2 times of the medical material gross weight added, being subsequently adding the Radix Aucklandiae and step (1) the gained Radix Pulsatillae, boil to boiling with big fire, rear turn of little fire decocts 35 minutes, leach medicinal liquid, to obtain final product.

Instructions of taking: every day twice, each 280mL(decoction being taken warmly).

Embodiment 2 chronic dysentery is invigorated blood circulation dysentery stopping preparation, and the primary raw material medicine taking following weight is prepared from: Rhizoma Coptidis 6g, Radix Pulsatillae 20g, Radix Aucklandiae 15g, Herba Polygoni Capitati 25g, Ramulus et Folium Bischofiae Javanicae 12g, Radix Astragali 20g, Radix Angelicae Sinensis 10g, Ramulus Cinnamomi 15g, Herba Portulacae 40g, Rhizoma Chuanxiong 12g, Radix Thyrocarpi sampsonii 15g, straw sandals green grass or young crops 9g.

The invigorate blood circulation preparation method of dysentery stopping preparation powder of chronic dysentery is:

(1) Radix Pulsatillae is removed impurity, clean dust, be soaked in water 25 minutes, drag in basket, add a cover wet cloth and moisten 5 hours, take out, section, then soak 2.5 hours with wine, take out, dry, be ground into fine powder, cross 150 mesh sieves;

(2) all the other crude drug except the Radix Pulsatillae being removed impurity, attrition grinding becomes fine powder respectively, crosses 150 mesh sieves;

Model case one: once XX, man, 46 years old. Chronic dysentery 3 years. Just because unhygienic diet causes acute toxic dysentery, heal through rescue. After 3 months, suffering from dysentery, stool day 8-9 time, tenesmus, just band pus and blood again because drinking and eating raw food, once took XIELITING and transfusion etc., all diseases disappear, but hereafter slightly namely diet recurs accidentally. Over nearly 1 year, dysentery ceaselessly, all over taking Chinese and western drugs, dysentery is not recovered eventually existing stool every day for several times, and just band pus and blood accompanies tenesmus, tenesmus, feverish sensation in the palms and soles, excessive thirst, few abdomen is lasting continuous has a pain, and happiness is warm presses temperature food, but appetite is very few, waist is aching and limp to be sent out cool, and shallow complexion shades, look asthenia, faint low voice, pale tongue tongue is white, thready and rapid pulse without strength. Taking the present embodiment gained chronic dysentery to invigorate blood circulation dysentery stopping preparation powder, every day twice, each 5 grams, boiled water is taken after mixing it with water. Taking two days, stool every day 2 times, slightly shape, mycopus amount subtracts, and blood almost loses, and the disease such as stomachache, tenesmus, feverish sensation in the palms and soles all has and alleviates in various degree. Taking 4 days, stool every day 1 time, shape, in just, band blood and stomachache pain in the abdomen lose, and diet increases, and spirit takes a turn for the better, but still have a small amount of mucus in stool, time feel thirsty. After taking 6 days, all diseases disappear, and sick announcement is fully recovered. Follow up a case by regular visits to and do not recur.

Embodiment 3 chronic dysentery is invigorated blood circulation dysentery stopping preparation, and the primary raw material medicine taking following weight is prepared from: Rhizoma Coptidis 4g, Radix Pulsatillae 13g, Radix Aucklandiae 8g, Herba Polygoni Capitati 19g, Ramulus et Folium Bischofiae Javanicae 8g, Radix Astragali 15g, Radix Angelicae Sinensis 7g, Ramulus Cinnamomi 11g, Herba Portulacae 24g, Rhizoma Chuanxiong 9g, Radix Thyrocarpi sampsonii 8g, straw sandals green grass or young crops 6g.

The invigorate blood circulation thick paste agent preparation method of dysentery stopping preparation of chronic dysentery is:

(1) Radix Pulsatillae is removed impurity, clean dust, be soaked in water 25 minutes, drag in basket, add a cover wet cloth and moisten 5 hours, take out, section, then soak 2.5 hours with wine, take out;

(2) being placed in marmite by all the other the 10 taste crude drugs except the Radix Pulsatillae and the Radix Aucklandiae, add water, the consumption of water is 4.5 times of the medical material gross weight added, soaks 2 hours;

(3) medical material step (2) soaked first boils to boiling with big fire, rear turn of little fire decocts 22 minutes, add water, the consumption of water is 3.2 times of the medical material gross weight added, it is subsequently adding the Radix Aucklandiae and step (1) the gained Radix Pulsatillae, boiling to boiling with big fire, rear turn of little fire decocts 42 minutes, leaches medicinal liquid;

(4) step (3) gained medicinal liquid is reduced pressure, be concentrated into the clear paste that relative density is 1.3, be subsequently adding adjuvant and mix well, dress aseptic bottle seals and get final product.

Model case two: high XX, female, 40 years old. Suffer from dysentery 2 years, take Western medicine, Chinese patent medicine and Chinese medicine decoction and fail eventually more. Now Mucous Stool every day 5-7 time, just band pus and blood, less abdominal part dull pain, to like Wen Xinuan, meet abdominal pain due to cold dysentery weight, tenesmus, not freely, awareness of defecation is most, bitter taste, red tongue, yellow and greasy fur, soft and rapid pulse for stool. Take the present embodiment gained chronic dysentery to invigorate blood circulation dysentery stopping preparation thick paste agent, every day three times, each 25 grams. Taking medicine 2 days, stool every day 3 times, shapeless, mucus reduces, and blood almost loses, and symptom alleviates, and body of the tongue is slightly red, yellow and thin fur, still feels slightly cool in abdomen. Taking 4 days, stool is basic to be shaped, and mucus almost loses, and appetite increases, and all diseases disappear substantially. Take 6 days, recovery from illness. Follow up a case by regular visits to and have no recurrence.

Embodiment 4 chronic dysentery is invigorated blood circulation dysentery stopping preparation, and the primary raw material medicine taking following weight is prepared from: Rhizoma Coptidis 5.5g, Radix Pulsatillae 16g, Radix Aucklandiae 12g, Herba Polygoni Capitati 22g, Ramulus et Folium Bischofiae Javanicae 11g, Radix Astragali 18g, Radix Angelicae Sinensis 9g, Ramulus Cinnamomi 13g, Herba Portulacae 32g, Rhizoma Chuanxiong 11g, Radix Thyrocarpi sampsonii 11g, straw sandals green grass or young crops 8g.

The invigorate blood circulation preparation method of dysentery stopping preparation pill of chronic dysentery is:

(1) Radix Pulsatillae is removed impurity, clean dust, be soaked in water 25 minutes, drag in basket, add a cover wet cloth and moisten 5 hours, take out, section, then soak 2.5 hours with wine, take out, dry, be ground into fine powder, cross 130 mesh sieves;

(2) all the other crude drug except the Radix Pulsatillae are removed impurity, after drying, these medicines are mixed together and are ground into fine powder, cross 130 mesh sieves, then fully mix with step (1) gained fine powder;

(3) being joined by refined honey in step (2) gained mixing fine powder, the weight of refined honey is 1.3 times of medicine gross weight, makes little pill, and the particle diameter of little pill is 3mm.

Model case three: woods XX, female, 60 years old. First visit on April 25 in 2009. Suffer from more than dysentery June, more than under dysentery, lower mucoid stool, the band blood streak, accompany tenesmus, xerostomia is weak, red tongue, yellow and thin fur, thready and rapid pulse. Once with the treatment such as intravenous drip Ceftriaxone, amikacin many days, the first used time take a favorable turn, after gradually invalid, defecate still under day dysentery for several times. Take the present embodiment gained chronic dysentery to invigorate blood circulation dysentery stopping preparation pill, every day three times, each 15. Being used in conjunction 4 days, sick announcement is fully recovered. The blood streak loses. Following up a case by regular visits to 2 years, disease is not sent out again.

Embodiment 5 chronic dysentery is invigorated blood circulation dysentery stopping preparation, and the primary raw material medicine taking following weight is prepared from: Rhizoma Coptidis 5g, Radix Pulsatillae 14g, Radix Aucklandiae 10g, Herba Polygoni Capitati 21g, Ramulus et Folium Bischofiae Javanicae 9g, Radix Astragali 17g, Radix Angelicae Sinensis 8g, Ramulus Cinnamomi 12g, Herba Portulacae 29g, Rhizoma Chuanxiong 10g, Radix Thyrocarpi sampsonii 9g, straw sandals green grass or young crops 7g.

(3) medical material step (2) soaked first boils to boiling with big fire, rear turn of little fire decocts 22 minutes, add water, the consumption of water is 3.2 times of the medical material gross weight added, being subsequently adding the Radix Aucklandiae and step (1) the gained Radix Pulsatillae, boil to boiling with big fire, rear turn of little fire decocts 42 minutes, leach medicinal liquid, to obtain final product.

Test example 1: in order to verify that embodiment 5 gained chronic dysentery is invigorated blood circulation the drug effect of dysentery stopping preparation, We conducted contrast test. Experiment screening chronic dysentery patient 248 people, is divided into matched group and experimental group randomly, and every panel size is identical, is respectively 124 people. Experimental group: take embodiment 5 gained chronic dysentery and invigorate blood circulation dysentery stopping preparation decoction, instructions of taking: every day twice, each 280mL(decoction being taken warmly). Matched group: use the medicine of the conventional therapy chronic dysenterys such as norfloxacin, bactrim, Berberine Tablet. Curative effect situation criterion: cure: clinical symptoms, sign disappear, and the lab testing such as stool routine examination, routine blood test is often all become a full member; Effective: clinical symptoms, sign disappear substantially, the index such as routine blood test, stool routine examination major part is normal; Take a turn for the better: clinical symptoms, sign take a turn for the better, and routine blood test, stool routine examination part are normal; Invalid: clinical symptoms and sign, blood and stool routine examination check without improving. Result is as shown in the table:

Table 1: embodiment 5 gained chronic dysentery is invigorated blood circulation dysentery stopping preparation decoction compliance test result

Therapeutic effect: cure 76 examples (61.29%), effective 45 examples (36.29%), 3 examples that take a turn for the better (2.42%), total effective rate 97.58%. Effect is substantially better than matched group.

The present invention selects Rhizoma Coptidis, the Radix Pulsatillae, the Radix Aucklandiae, Herba Polygoni Capitati etc. to carry out compatibility so that these medicines produce synergism, it is possible to more effectively treat chronic dysentery. Radix Pulsatillae heat-clearing and toxic substances removing in side, eliminating pathogenic heat from blood to cure dysentery. Rhizoma Coptidis bitter cold has the effect of heat clearing and damp drying, consolidating YIN eliminating fire and detoxication. Radix Aucklandiae promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion. Herba Polygoni Capitati detoxifies, dissipating blood stasis, inducing diuresis for treating stranguria syndrome. Ramulus et Folium Bischofiae Javanicae expelling wind and removing dampness, blood stasis dispelling removing food stagnancy. Radix Astragali invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation. Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation. Ramulus Cinnamomi expelling cold and relieving exterior syndrome, promoting the flow of QI-blood by warming the meridian. Herba Portulacae heat-clearing and toxic substances removing, cooling blood for hemostasis. Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping. Radix Thyrocarpi sampsonii clearing heat, releasing toxin, removing swelling. Straw sandals green grass or young crops heat-clearing and toxic substances removing. All medicine compatibilities, play the effect of heat-clearing and toxic substances removing, loosening bowel to relieve constipation, dysentery relieving of invigorating blood circulation altogether. Chronic dysentery of the present invention dysentery stopping preparation of invigorating blood circulation is evident in efficacy.

It should be pointed out that, the detailed description of the invention more representational example that is the present invention, it is clear that technical scheme is not limited to above-described embodiment, it is also possible to have many variations. Those of ordinary skill in the art, with the present invention undoubted the obtaining of clearly disclosed or according to file written description, be all considered as this patent scope of the claimed.

Claims

1. chronic dysentery is invigorated blood circulation dysentery stopping preparation, it is characterised in that takes off the primary raw material medicine stating weight proportion and is prepared from: Rhizoma Coptidis 4, the Radix Pulsatillae 13, the Radix Aucklandiae 8, Herba Polygoni Capitati 19, Ramulus et Folium Bischofiae Javanicae 8, the Radix Astragali 15, Radix Angelicae Sinensis 7, Ramulus Cinnamomi 11, Herba Portulacae 24, Rhizoma Chuanxiong 9, Radix Thyrocarpi sampsonii 8, straw sandals green grass or young crops 6.

2. chronic dysentery according to claim 1 is invigorated blood circulation the preparation method of dysentery stopping preparation thick paste agent, it is characterised in that