CN112755162A

CN112755162A - Composition for treating chilblain

Info

Publication number: CN112755162A
Application number: CN202110110986.8A
Authority: CN
Inventors: 李友贵
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-01-27
Filing date: 2021-01-27
Publication date: 2021-05-07

Abstract

The application discloses a composition for treating chilblain, which comprises the following components in parts by weight: 2-5 parts of sargentgloryvine stem, 5-7 parts of ginger, 8-10 parts of rose, 30-40 parts of cherry, 2-4 parts of angelica sinensis, 4-8 parts of safflower, 2-4 parts of akebiaquinata, 4-8 parts of fennel, 4-8 parts of motherwort, 3-6 parts of ligusticum wallichii, 5-8 parts of pseudo-ginseng, 2-6 parts of jasmine, 60-70 parts of white spirit and 3-5 parts of dragon's blood. The composition for treating chilblain is prepared by selecting traditional Chinese medicinal materials, cherry, rose, jasmine, ginger and the like and adopting high-alcohol-content white spirit; the external use liniment achieves the effects of prevention and treatment by a skin absorption mode, is safe without side effect, and can play the effects of bacteriostasis and sterilization.

Description

Composition for treating chilblain

Technical Field

The invention relates to the field of traditional Chinese medicine compositions, in particular to an externally applied liquid composition, and specifically relates to a composition for treating chilblain.

Background

Chilblain is usually caused in early winter and early spring, and most of children, women and peripheral poor blood circulation are accompanied by cold skin at the extremities, cyanosis of extremities, hyperhidrosis and the like. Skin lesions are usually located on the fingers, back of hand, face, pinna, toes, edges of feet, and heel, and often distributed on both sides. The common lesions are localized gorgeous dark purplish red swollen edematous erythema, unclear boundaries, bright red edges, tense and glossy surfaces and soft texture. The color faded by local compression, and the red color gradually recovers after decompression. In severe cases, blisters may develop, rupture to form erosions or ulcers, and the healed skin may contain pigmentation or atrophic scars. Itching is obvious, aggravated after being heated and pain after ulceration.

The existing chilblain plaster, liquid medicine or spray has various types and great differences in treatment effects, and at present, numerous and complicated chilblain auxiliary products, preventive products and treatment medicines on the market are various, but no known product with good treatment effect exists. Meanwhile, the product is a curative effect product without certainty and industry recognition aiming at the influence of different individual symptoms, different tolerance and other factors.

The western medicine field has a consistent theorem for chilblain, namely the effects of expanding blood vessels, improving microcirculation, increasing blood flow and dissolving thrombus are finally realized through oral administration or other auxiliary modes so as to achieve the purpose of improving and radically treating chilblain.

Disclosure of Invention

In order to solve the trouble and discomfort brought by chilblain, the application provides a composition for treating chilblain, and the composition is externally applied, so that the skin absorbs the composition to promote blood circulation and remove blood stasis, promote blood circulation and reduce or avoid the probability of chilblain recurrence, and the problem of the chilblain patients suffering from chilblain in cold winter is solved.

In order to achieve the purpose, the technical scheme adopted by the application is as follows:

a composition for treating chilblain comprises the following components in parts by weight: 2-5 parts of sargentgloryvine stem, 5-7 parts of ginger, 8-10 parts of rose, 30-40 parts of cherry, 2-4 parts of angelica sinensis, 4-8 parts of safflower, 2-4 parts of akebiaquinata, 4-8 parts of fennel, 4-8 parts of motherwort, 3-6 parts of ligusticum wallichii, 5-8 parts of pseudo-ginseng, 2-6 parts of jasmine, 60-70 parts of white spirit and 3-5 parts of dragon's blood.

As one of the preferable formulas of the application, 3-4 parts of sargentgloryvine stem, 6-7 parts of ginger, 9 parts of rose, 32-38 parts of cherry, 3 parts of angelica, 5-7 parts of safflower, 3 parts of akebia stem, 5-7 parts of fennel, 5-7 parts of motherwort, 4-5 parts of ligusticum wallichii, 7 parts of pseudo-ginseng, 3-5 parts of jasmine flower, 62-67 parts of white spirit and 4 parts of dragon's blood are weighed according to the mass parts.

According to a further preferable formula scheme, the traditional Chinese medicine composition comprises, by mass, 4 parts of sargentgloryvine stem, 7 parts of ginger, 9 parts of rose, 36 parts of cherry, 3 parts of Chinese angelica, 6 parts of safflower, 3 parts of akebia stem, 6 parts of fennel, 6 parts of motherwort, 5 parts of ligusticum wallichii, 7 parts of pseudo-ginseng, 4 parts of jasmine, 65 parts of white spirit and 4 parts of dragon's blood.

Preferably, the ginger is fresh old ginger, the rose is dehydrated dry rose, the cherry is fresh red cherry, and the jasmine is dehydrated dry jasmine. The alcoholic strength concentration of the white spirit is not lower than 60%. In order to further shorten the soaking time and improve the drug effect, the ginger is sliced for use, and the thickness of a single slice is less than 1 mm; puncturing or crushing cherries; cutting caulis Sargentodoxae, radix Angelicae sinensis, caulis Akebiae, fructus Foeniculi, rhizoma Ligustici Chuanxiong, Notoginseng radix and sanguis Draxonis into small segments or pulverizing.

The related components in the formula have the following functions:

sargentgloryvine stem:

the sargentgloryvine stem and large intestine meridian has excellent functions of detoxicating, relieving pain, promoting blood circulation, dispelling wind and eliminating dampness. The sargentgloryvine stem has better effects of activating blood and dredging channels and collaterals, can improve qi and blood circulation of a human body, and has the effects of enhancing physique and improving the immunity of the human body at the same time; and can be used for treating enterodynia, heat sore, toxic and external diseases, rheumatalgia, and swelling and blood stasis.

Ginger:

ginger has the actions of warming spleen and stomach, dispelling cold, relieving exterior syndrome and dispelling cold. The folk popular saying that the radish going to bed and the ginger going to bed do not need a prescription of a doctor is to explain that the ginger has the effect of dispersing wind cold, the ginger can disperse cold evil and prevent cold, and the ginger can be used for treating symptoms such as aversion to cold and fever caused by wind cold. Ginger also has the function of detoxification, such as the poison of fish and crab, and also has the effects of bacteriostasis and sterilization.

And (3) rose:

the rose contains a large amount of nutrient elements such as vitamins, amino acids, alkaloids, basic protein, carbohydrates and the like, and is also rich in mineral substances such as calcium, phosphorus, potassium, iron and the like and various aromatic phenols. The rose is warm in nature, has the effects of promoting blood circulation and removing blood stasis, and can play the effects of storing blood circulation and blood stasis and body cold in the links when being taken in the menstrual period of women.

Cherry:

the cherry contains abundant anthocyanidin, haematochrome, carotene, tartaric acid, and microelements such as iron, calcium, phosphorus, etc. The cherry has effects of promoting blood circulation, promoting uric acid excretion, and relieving discomfort caused by ventilation and arthritis. Quercetin in cherry is an antioxidant, and has important effects in resisting inflammation and scavenging free radicals. The iron content of the cherries is high, and the iron content of each hundred grams of cherries is up to 5.9 milligrams, and is positioned at the head of various fruits. The iron element is also a raw material for synthesizing human hemoglobin and myoglobin, and plays an important role in human immunity, protein synthesis and energy metabolism.

The anthocyanidin, haematochrome and the like contained in the cherry can effectively resist oxidation, have stronger anti-aging effect than vitamin E, and can promote blood circulation. Can relieve discomfort symptoms caused by ventilation and arthritis, and has the effects of relieving pain and diminishing inflammation. The cherry has the function of treating burn, and meanwhile, the cherry also has a certain function on frostbite, so that the cherry is a good nutritional fruit.

Chinese angelica:

radix Angelicae sinensis has effects in replenishing blood, promoting blood circulation, regulating menstruation and relieving pain. Dang Gui is sweet and heavy, so it can tonify blood, and its qi is light and pungent, so it can move blood, tonify middle energizer and tonify middle energizer, and is the essential herb in blood. Therefore, the angelica can enrich the blood and activate the blood, can dredge the channels and activate the collaterals, and has excellent important value in the aspect of activating the blood and dissolving stasis. The Chinese angelica is a soup which is the most common edible mode in the traditional Chinese medicine, has good effect on anemia patients, can also obviously promote the hematopoietic function and improve the content of red blood cell white blood cells and hemoglobin. After being soaked in high-alcohol liquor, the Chinese medicinal composition can stimulate the medicinal effect, is effectively absorbed by the skin of a human body, promotes the blood circulation of subcutaneous tissues, improves the blood flow, and achieves the effects of promoting blood circulation and removing blood stasis.

Safflower:

safflower, name of Chinese medicine. Collected in the shade or dried in the sun when the flowers turn yellow and red in summer. The cultivation is widely carried out all over the country. Has the functions of promoting blood circulation to restore menstrual flow, eliminating blood stasis and relieving pain. Can be used for treating amenorrhea, dysmenorrhea, lochiorrhea, abdominal mass, thoracic obstruction, cardialgia, abdominal pain due to blood stasis, pricking pain in chest and hypochondrium, traumatic injury, and pyocutaneous disease with swelling and pain.

B, wood through:

akebia quinata is bitter and cold in property, and enters heart channel, small intestine channel and bladder channel; has the effects of inducing diuresis for treating stranguria, clearing away heart-fire and relieving restlessness, and stimulating the menstrual flow and promoting lactation. Modern medical pharmacology research proves that the akebia stem has an anti-inflammatory effect and certain auxiliary effects on promoting urination, inhibiting thrombosis, reducing blood fat, resisting oxidation, resisting stress and the like.

Fennel:

the whole herb and spica are commonly used Chinese herbs, and are mostly used for relieving exterior syndrome, and can be used for treating wind-cold type common cold, headache, sore throat, menorrhagia, metrorrhagia, infantile fever and convulsion, furuncle, scabies, acute contagious conjunctivitis, wind-fire toothache, eczema, urticaria and skin pruritus. The whole herb is rich in aromatic oil, and the aromatic oil can be extracted. The fennel has the functions of invigorating stomach, regulating qi, sterilizing, dispelling cold and relieving pain, is pungent in taste and warm in nature, and mainly enters lung, stomach and kidney meridians. Meanwhile, the fennel has good sterilization and anti-inflammation effects and plays a role in dispelling cold and relieving pain; it can also be used for treating cold pain of waist and knee, and hernia of lower abdomen caused by cold obstruction of kidney channel.

Motherwort:

motherwort herb, the name of traditional Chinese medicine. Harvesting fresh products from a spring seedling stage to an early summer flower stage; collecting the dried product in summer when stem and leaf flourish, flower do not bloom or bloom, sun-drying, or cutting and sun-drying. Widely distributed all over the country. Has the effects of promoting blood circulation, regulating menstruation, inducing diuresis, relieving swelling, and clearing away heat and toxic materials. Can be used for treating menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema, oliguria, pyocutaneous disease, and toxic swelling. Meanwhile, the motherwort has good effects of inducing diuresis and reducing edema, and has obvious curative effect on edema of lower limbs caused by water metabolism diseases of human bodies due to various reasons; meanwhile, obstructive diseases can be treated. Such as prostatic hyperplasia in men or difficulty in urination due to obstruction of the bladder neck in women.

Rhizoma Ligustici Chuanxiong

Ligusticum wallichii (with the scientific name of Ligusticum chuanxiong Hort) is cultivated in Sichuan (Shuichuan) and grows in the places of Yunnan, Guizhou, Guangxi and the like in mild climatic environment. Is a traditional Chinese medicine plant which is commonly used for promoting blood circulation and promoting qi circulation, dispelling wind and relieving pain, and the ligusticum wallichii is pungent, warm, fragrant and dry and can disperse and ascend to the vertex; it enters the blood system and goes down to reach the blood sea. Promoting blood circulation and removing blood stasis, and is suitable for various diseases caused by blood stasis; can be used for treating headache due to wind, and rheumatalgia. Xiren is that Chuan Xiong is a qi-flowing medicine in blood, but it has the functions of dispersing acrid, relieving depression, dredging and relieving pain.

Pseudo-ginseng:

the rhizome and fleshy root are rare traditional Chinese medicines, have the effects of stopping bleeding, breaking blood and dissipating blood stasis, diminishing inflammation and relieving pain and nourishing, and are main medicines for treating traumatic injuries. Flowers and leaves also have the effect of clearing heat. The clinical research shows that the panax notoginseng also has the function of anti-aging, and the panax notoginseng contains panaxatriol saponin, so that the panax notoginseng can excite the central nerve of the brain of a human body, promote the blood circulation of the brain and resist the fatigue of the brain.

Jasmine flower:

jasmine flower: pungent, sweet and warm. Regulating qi, resolving stagnation, removing filth, and regulating the middle warmer. It can be used for treating abdominal pain due to dysentery, conjunctival congestion, red swelling, and sore. The jasmine flower has the effects of relieving swelling and detoxifying, has good effects of clearing liver and improving vision, promoting fluid production to quench thirst, dispelling wind and detoxifying, reducing blood pressure and resisting aging, and the volatile oil substances contained in the jasmine flower have the effects of promoting qi circulation and relieving pain, resolving stagnation and dissipating stagnation, and can relieve chest and abdomen distending pain, relieve swelling and detoxifying, calm nerves and relieve emotion.

White spirit:

the white spirit has the functions of promoting human metabolism and promoting human blood circulation, is particularly obvious in cold winter, and can effectively improve the human metabolism.

Dragon's blood:

has good effects of promoting blood circulation, relieving pain, removing blood stasis, stopping bleeding, healing sore and promoting granulation. It is mainly used for treating traumatic injury, heart and abdomen blood stasis and pain, traumatic hemorrhage, unhealed skin and external diseases, etc.

Has the advantages that:

the composition for treating chilblain is prepared by selecting traditional Chinese medicinal materials, cherry, rose, jasmine, ginger and the like and adopting high-alcohol-content white spirit; the external use liniment achieves the effects of prevention and treatment by a skin absorption mode, is safe without side effect, and can play the effects of bacteriostasis and sterilization.

Detailed Description

All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

Example 1:

a composition for treating chilblain is prepared from 2 parts of sargentgloryvine stem, 5 parts of ginger, 8 parts of rose, 30 parts of cherry, 2 parts of Chinese angelica, 4 parts of safflower, 2 parts of akebia stem, 4 parts of common fennel, 4 parts of motherwort, 3 parts of ligusticum wallichii, 5 parts of pseudo-ginseng, 2 parts of jasmine flower, 60 parts of white spirit and 3 parts of dragon's blood.

Example 2:

a composition for treating chilblain comprises, by mass, 4 parts of sargentgloryvine stem, 7 parts of ginger, 9 parts of rose, 36 parts of cherry, 3 parts of Chinese angelica, 6 parts of safflower, 3 parts of akebia stem, 6 parts of common fennel, 6 parts of motherwort, 5 parts of ligusticum wallichii, 7 parts of pseudo-ginseng, 4 parts of jasmine flower, 65 parts of white spirit and 4 parts of dragon's blood.

Example 3:

a composition for treating chilblain comprises, by mass, 5 parts of sargentgloryvine stem, 7 parts of ginger, 10 parts of rose, 40 parts of cherry, 4 parts of Chinese angelica, 8 parts of safflower, 4 parts of akebia stem, 8 parts of fennel, 8 parts of motherwort, 6 parts of ligusticum wallichii, 8 parts of pseudo-ginseng, 6 parts of jasmine flower, 70 parts of white spirit and 5 parts of dragon's blood.

Example 4:

a method for preparing a composition for treating chilblain comprises slicing rhizoma Zingiberis recens, wherein the thickness of single slice is less than 1 mm; puncturing or crushing cherries; caulis Sargentodoxae, radix Angelicae sinensis, caulis Akebiae, fructus Foeniculi, herba Leonuri, rhizoma Ligustici Chuanxiong, Notoginseng radix and sanguis Draxonis by cutting into small segments. The rose, safflower and jasmine flower are not specially treated. The components are accurately weighed according to the preset parts by mass and are placed in a brown or light-shielding closed glass or ceramic container. Finally, pouring the white spirit into the container, and placing a heavy object made of glass or ceramic materials on the surface of the container to avoid the problem that the medicinal materials are floated and cannot be completely soaked in the white spirit; after soaking for 10 days, manually stirring or turning over to completely submerge all the materials in the formula in the white spirit, and continuously soaking for more than 2 months.

Example 5:

soaking 2 parts of rhubarb, 2 parts of hot pepper, 1.5 parts of camphor and 1.5 parts of borneol in 50 parts of white spirit with the alcoholic strength of 55% vol for fermentation for 7 months. Then filtering the composition after soaking and fermenting, collecting the filtrate and storing for later use.

Example 6:

the applicant associates several chilblain patients with different ages with the same location and periphery to participate in the curative effect experiment, and collects case samples for years to obtain the following information:

the number of participants is 24, the symptoms are at least obvious visual red and swollen, the skin is more than purple, and the phenomena of cracking, opening and bleeding appear on part of the skin; participants ranged in age from 8-62 years; the 24 participants were divided into 4 groups of A-D, and 6 of each group had at least 2 male patients or female patients.

Composition 1: the composition obtained by the preparation method of example 4 was prepared according to the formulation in example 1.

Composition 2: the composition obtained by the preparation method of example 4 was prepared according to the formulation in example 2.

Composition 3: the composition obtained by the preparation method of example 4 was prepared according to the formulation in example 3.

Composition 4: the composition obtained according to the formulation and preparation method of example 5. The composition adopts the technical scheme that the publication number is CN109045147A, and the subject names are: the technical contents disclosed by the invention patent application of the preparation raw material and the application of the chilblain medicine, the preparation raw material of the chilblain liquid, the chilblain liquid and the preparation method thereof are prepared as the prior art and are used as a control group of the chilblain liquid.

The details are shown in table 1 below:

the applicant/inventors have personally experienced the above compositions 3 and 4, and the conditions and feelings of use are as follows:

the plum is friendly, male is 49 years old, and the fingers of the male are suffered from red swelling, scalding, pruritus and ulceration caused by long-term cold sores in winter. Composition 4 was prepared according to the method of example 5 starting at 1 month 2019, and after a half-year fermentation, the filtrate of composition 4 was obtained and applied to the affected area, after which there was a clear cooling sensation, but after about 2 minutes the liquid medicine had evaporated, the repentance felt increasingly intense heat and even tended to burn. The finger paste is applied for 2-3 times every day for 10 days, but the application is always kept once every morning and evening, the red swelling of the finger roots of the two hands is obvious before the finger paste is used, a plurality of cracks exist in joints, tissue fluid or a small amount of blood can be squeezed out when the finger paste is serious, and the finger is obviously painful when the finger is used for making a fist. After the finger-nail-shaped punch is used, the cracks are obviously scabbed, the finger-nail-shaped punch is difficult to bend, the red swelling is not obviously subsided, but the finger-nail-shaped punch is improved in sense and is not cured.

In the same year, within one week after application of composition 4, hands were washed daily with skin soothing soap and then applied three times daily with composition 3. The application operation is as follows:

pouring the composition 3 into a proper amount of the palm, quickly rubbing repeatedly, applying to the affected part after the palm can feel obvious temperature rise, and continuously gently softening to heat the affected part, thereby facilitating the absorption of the composition 3. The amount of each application is ensured to completely cover the whole affected part.

After the Chinese medicinal composition is used for 4 days, swelling is obviously relieved, the temperature of fingers is reduced in the evening, obvious slight wrinkles can be seen on the skin, the looseness of muscles is increased, and cracks are scabbed and partially fall off. After the continuous use till the 8 th day, the finger dimension of the finger is recovered to be normal, the skin has wrinkles, the crack is healed, and although obvious scars or traces are observed at the visual crack, no new crack is found. After the chilblain is continuously used for 10 days, all chilblain symptoms completely disappear, and the chilblain does not relapse until the next 3 months.

In the participants, all the healers have no repeated phenomenon after healing in the current year, but the chilblain symptoms are almost all caused in the following years, and the composition provided by the invention can not realize one-time permanent radical cure. The same therapeutic effect can be achieved by continuing treatment with the compositions provided herein the following year. However, whether the composition provided by the application can be used repeatedly for many times or not and how many times the composition needs to be repeated can be treated radically permanently, based on the reason of experimental time period, objective treatment is not obtained, but a single repeated smearing administration can obtain a remarkable curative effect and is obviously beneficial to patients, and the dosage concentration is increased or the action time and times are increased, so that the patients can benefit more. Aiming at severe chilblain patients with cracks, suppurations and the like, the patients can benefit by increasing the smearing times, and the treatment period is shortened.

The above description is only a preferred embodiment of the present application and is not intended to limit the present application, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A composition for treating chilblain, comprising: the composition comprises the following components in percentage by weight: 2-5 parts of sargentgloryvine stem, 5-7 parts of ginger, 8-10 parts of rose, 30-40 parts of cherry, 2-4 parts of angelica sinensis, 4-8 parts of safflower, 2-4 parts of akebiaquinata, 4-8 parts of fennel, 4-8 parts of motherwort, 3-6 parts of ligusticum wallichii, 5-8 parts of pseudo-ginseng, 2-6 parts of jasmine, 60-70 parts of white spirit and 3-5 parts of dragon's blood.

2. The composition for treating chilblain according to claim 1, wherein: the composition comprises the following components in percentage by weight: 3-4 parts of sargentgloryvine stem, 6-7 parts of ginger, 9 parts of rose, 32-38 parts of cherry, 3 parts of angelica sinensis, 5-7 parts of safflower, 3 parts of akebia stem, 5-7 parts of fennel, 5-7 parts of motherwort, 4-5 parts of ligusticum wallichii, 7 parts of pseudo-ginseng, 3-5 parts of jasmine flower, 62-67 parts of white spirit and 4 parts of dragon's blood.

3. The composition for treating chilblain according to claim 1, wherein: the composition comprises the following components in percentage by weight: 4 parts of sargentgloryvine stem, 7 parts of ginger, 9 parts of rose, 36 parts of cherry, 3 parts of Chinese angelica, 6 parts of safflower, 3 parts of akebia stem, 6 parts of fennel, 6 parts of motherwort, 5 parts of ligusticum wallichii, 7 parts of pseudo-ginseng, 4 parts of jasmine, 65 parts of white spirit and 4 parts of dragon's blood.

4. The composition for treating chilblain according to any one of claims 1-3, wherein: the ginger is fresh old ginger, the rose is dehydrated dry rose, the cherry is fresh red cherry, and the jasmine is dehydrated dry jasmine.

5. The composition for treating chilblain according to claim 4, wherein: the alcoholic strength concentration of the white spirit is not lower than 60%.

6. The composition for treating chilblain according to claim 5, wherein: the ginger is sliced, and the thickness of a single slice is less than 1 mm; puncturing or crushing cherries; cutting caulis Sargentodoxae, radix Angelicae sinensis, caulis Akebiae, fructus Foeniculi, rhizoma Ligustici Chuanxiong, Notoginseng radix and sanguis Draxonis into small segments or pulverizing.