CN105726777A - Chinese herbal plaster for treating shoulder, neck and leg pain and skin and external diseases - Google Patents

Chinese herbal plaster for treating shoulder, neck and leg pain and skin and external diseases Download PDF

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Publication number
CN105726777A
CN105726777A CN201610147813.2A CN201610147813A CN105726777A CN 105726777 A CN105726777 A CN 105726777A CN 201610147813 A CN201610147813 A CN 201610147813A CN 105726777 A CN105726777 A CN 105726777A
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herba
radix
skin
folium
blood
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徐庆田
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
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    • A61K33/00—Medicinal preparations containing inorganic active ingredients
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    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A61K36/12—Filicopsida or Pteridopsida
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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Abstract

The invention relates to the field of Chinese herbal medicine application, in particular to Chinese herbal plaster for treating shoulder, neck and leg pain and skin and external diseases.The Chinese herbal plaster for treating shoulder, neck and leg pain and skin and external disease is prepared by decumbent bugle herb, folium polygoni tinctorii, folium ilicis chinensis, sculellaria barbata, nandina domestica thumb, frangipani, lotus leaf, rockfoil, mesona chinensis, rehmannia, shrub althea flower, cortex Lycii, cortex dictamni, oxalidaceae, coptis chinensis, astragalus membranaceus, radix rubiae, common cephalanoplos herb, flos sophorae, bryophyllum, eclipta, spiny amarauth herb, sanguisorba officinalis, pseudo-ginseng, acacia catechu, drynaria rhizome, rhizoma bolbostemmae, folium psychotriae rubrae, calamine, thymifoious euphorbia herb, and houttuynia cordata according to a certain proportion.The Chinese herbal plaster is simple to prepare, good in absorption effect, long in effective duration, remarkable in curative effect, free of toxic and side effect, highly safe, low in production cost, and can alleviate symptoms of patients in time.

Description

A kind for the treatment of takes on the Chinese medicine plaster that neck has a pain in the leg bitterly, sores ulceration of skin is sick
(1) technical field
The present invention relates to application in TCM field, treat, particularly to a kind of, the Chinese medicine plaster that shoulder neck has a pain in the leg bitterly, sores ulceration of skin is sick.
(2) background technology
The paathogenic factor of skin infection, has diseases caused by exogenous pathogenic factor (diseases caused by exogenous pathogenic factor six climate exopathogens heresy poison, experience special malicious, external injury etc.) and internal injury (feelings will internal injury, eating and drinking without temperance, chamber damage etc.) two big classes.The skin infection that exopathogen causes, the most common with " pyretic toxicity ", " fire-toxin ", skin infection that wind and cold heat-damp in summer etc. causes, have in the initial phase, not necessarily all there is the red heat phenomenon of pyretic toxicity, fire-toxin, in out of contior situation, sick to mid-term, just can manifest.This kind of skin infection generally all has the feature of YANG syndrome skin infection because after skin infection occurs, pathological process is development and change, and the final performance of skin infection, be mostly pyretic toxicity, fire-toxin as.The skin infection that internal injury causes, mostly because void is caused a disease, and belongs to chronic more, such as network sky of suffering from a deficiency of the kidney, easily forms the tuberculosis of bone and joint for the turbid invasion and attack of wind and cold expectorant；Deficiency of YIN of both the lung and kidney, hyperactivity of deficient fire, bright Tianjin be expectorant form this kind of skin infection of scrofula just, there is mid-term the feature of YIN syndrome skin infection more.Additionally, due to eating and drinking without temperance, disorder of the spleen and stomach caused by internal damage, cause raw in fire-toxin and cause skin infection, although healthy energy not yet void declines sometimes, but mostly is serious than single for exopathogen causer, as diabetes merges furuncle, carbuncle etc..Therefore the generation of skin infection, it is common to thinking light from diseases caused by exogenous pathogenic factor receptor, internal organs accumulate poison from interior and originator weight.
The skin infection no matter that a kind of paathogenic factor causes, all can cause locally and systemically a series of pathological reactions.Energy and blood of human body, circumfluence all over the body, moves in endless cycles.After above-mentioned various paathogenic factors invade people's human body, will destroying this physiological function, cause local coagulation of QI-blood, disharmony of nutrient QI with defensive QI, meridians block, and produce to swell and ache symptom.As human disease resistance is low, and pathogenic factor can not control in time, then form hyperactivity of heat bringing about rottenness of muscle further, and meat corruption is pus, thus causing the formation of abscess.In the caking of internal organs, pain, suppuration, it is due to internal organs coagulation of QI-blood, the result that meridians block equally.During skin infection domination of pathogenic poison, it is possible to destroy human defense's function, by the conduction of meridians, it is possible to affect or invade people's internal organs, cause a series of inherent pathological reaction.Light then heating, thirsty, constipation occur, the disease such as red of urinating；Heavy then the diseases such as nausea and vomiting, dysphoria, unconsciousness and delirium, cough, sputum mixed with blood occur, even threat to life.
(3) summary of the invention
The present invention is in order to make up the deficiencies in the prior art, it is provided that a kind of prepare a kind of shoulder neck for the treatment of simple, evident in efficacy and has a pain in the leg the sick Chinese medicine plaster of pain, sores ulceration of skin.
The present invention is achieved through the following technical solutions:
A kind for the treatment of takes on the Chinese medicine plaster that neck has a pain in the leg bitterly, sores ulceration of skin is sick, is made up of the raw material of following parts by weight:
nullHerba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 15g-26g，Folium Polygoni Tinctorii 16g-29g，Ilex purpurea Hassk.[I.chinensis Sims 12g-26g，Herba Scutellariae Barbatae 10g-25g，Folium Nandinae domesticae 11g-25g，Flos Plumeriae Acutifoliae 11g-26g，Folium Nelumbinis 10g-26g，Herba Saxifragae 10g-25g，Herba mesonae chinensis 12g-29g，Radix Rehmanniae 10g-28g，Flos Hibisci 12g-29g，Cortex Lycii 10g-26g，Cortex Dictamni 10g-26g，Slurry grass 10g-26g，Rhizoma Coptidis 12g-26g，Radix Astragali 12g-25g，Radix Rubiae 10g-25g，Herba Cirsii 10g-24g，Flos Sophorae 12g-23g，Herba Bryophylli Pinnati 10g-25g，Herba Ecliptae 12g-25g，Amaranthus spinosus L. 12g-26g，Radix Sanguisorbae 11g-26g，Radix Notoginseng 12g-29g，Catechu 13g-29g，Rhizoma Drynariae 11g-25g，Rhizoma Bolbostematis 12g-26g，Red Psychotria Leaf 12g-28g，Calamina 10g-28g，Herba Euphorbiae Thymifoliae 10g-25g，Herba Houttuyniae 10g-28g.
The weight proportion of its preferred each raw material is:
Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 15g, Folium Polygoni Tinctorii 16g, Ilex purpurea Hassk.[I.chinensis Sims 12g, Herba Scutellariae Barbatae 10g, Folium Nandinae domesticae 11g, Flos Plumeriae Acutifoliae 11g, Folium Nelumbinis 10g, Herba Saxifragae 10g, Herba mesonae chinensis 12g, Radix Rehmanniae 10g, Flos Hibisci 12g, Cortex Lycii 10g, Cortex Dictamni 10g, slurry grass 10g, Rhizoma Coptidis 12g, Radix Astragali 12g, Radix Rubiae 10g, Herba Cirsii 10g, Flos Sophorae 12g, Herba Bryophylli Pinnati 10g, Herba Ecliptae 12g, Amaranthus spinosus L. 12g, Radix Sanguisorbae 11g, Radix Notoginseng 12g, catechu 13g, Rhizoma Drynariae 11g, Rhizoma Bolbostematis 12g, Red Psychotria Leaf 12g, Calamina 10g, Herba Euphorbiae Thymifoliae 10g, Herba Houttuyniae 10g.
Chinese medicine of the present invention is unguentum or powder, after being cleaned up by each raw material, makes unguentum or powder according to a conventional method, is externally applied to affected part and uses.
Wherein, the pharmaceutical characteristic of each raw material is as follows:
Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.): bitter, cold, nontoxic.Clearing away heat and cooling blood, detumescence of bringing down a fever.Antitussive, eliminate the phlegm, antiasthmatic effect: stimulate mice to cause the method for coughing and show with ammonia mist, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) acid alcohol extract 112, flavonoid glycoside, total acid phenol, total alkaloids, crystallization (I) and Saponin, all there is certain antitussive action, wherein the antitussive action similar intensity of flavonoid glycoside (2.5mg/ is only) and codeine (0.4mg/ is only)；It act as and directly suppresses coughing centre.Prove that acid alcohol extract 112, flavonoid glycoside, total acid phenol, alkaloid and crystallization (I) all have certain phlegm-dispelling functions by the phenol red method of mice；It act as directly stimulates respiratory mucosa secretory cell, make secretion increase, expectorant inner acidic mucopolysaccharide fiber is also had certain dissolution, and has the effect reducing capillary permeability, illustrate that its flavonoid glycoside can reduce the permeability of trachea during inflammation, thus playing antiinflammatory phlegm-dispelling functions.Experimental animal models asthma is had antiasthmatic effect in various degree by acid alcohol extract, flavonoid glycoside and alkaloid, and wherein the flavonoid glycoside of 250mg/kg is equal to the antiasthmatic effect of 125mg/kg aminophylline；Antiasthmatic effect is due to direct expansion bronchus smooth muscle and has caused by stronger anti-infectious function.Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) effective ingredient luteolin 250mg/kg gavage, 25mg/kg lumbar injection, draw ammonia mist and cough mice and all have an antitussive effect, 30mg/kg intravenous injection, and fiber crops cat stimulates superior laryngeal nerve draw to cough and also have inhibitory action；100mg/kg gavage, shows there is phlegm-dispelling functions to mice PSP method, 100mg/kg intravenous injection, and the bronchial smooth muscle that can antihistamine be caused shrinks.[br] 2. antiinflammatory immunity function: luteolin intramuscular injection, the mouse ear inflammation that xylol causes has obvious inhibiting effect, and its ED50 is 106mg/kg.Luteolin 80,160mg/kg intramuscular injection, on Carrageenan, rat ankle joint that yeast brings out is swollen, and swollen and Oleum Tiglii brings out and has rat granuloma all to have obvious inhibitory action, but 30,60mg/kg intramuscular injection, continuous 30 days, increasing the sickness rate of the experimental allergic encephalomyelitis of Cavia porcellus, prompting has immunological enhancement.Luteolin 80,120,160mg/kg intramuscular injection, the rat pleural that Dichlorodiphenyl Acetate brings out is scorching, and its transudate can be made to reduce, and to total white blood cells in transudate without obvious change.Luteolin 180mg/kg gavage, generates normal mouse hemolytic antibody and special red rose pigment rate has no significant effect, but improves cyclophosphamide and suppress the immunologic function of rabbit epidemic disease mice, makes these two indexs all improve.During the final concentration of 1.09 × 10-4mol/L of luteolin, suppressing sensitized guinea pig isolated ileal rings anaphylaxis contractile response, the guinea pig ileum that SRS-A is caused is shunk, and also has inhibitory action, and its IC50 is 2.76 × 10-5mol/L.Egg protein sensitized guinea pig lung rat tissue is discharged luteolin 4 × 10-4 concentration histamine and SRS-A also has inhibitory action.[br] be antibacterial, antivirus action 3.: alpha streptococcus, staphylococcus aureus, streptococcus pneumoniae, escherichia coli and bacillus pyocyaneus are had inhibitory action by alcohol-ether extract；Staphylococcus glucose coccus, alpha streptococcus, micrococcus catarrhalis and streptococcus pneumoniae are all had inhibitory action by flavonoid glycoside (10mg/ml)；10% Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) preserved material, 10% coated tablet and flavone all have the effect suppressing 68-1 influenza virus in obvious Embryo Gallus domesticus.Staphylococcus aureus, α-hemolytic streptococcus, micrococcus catarrhalis, streptococcus pneumoniae, bacillus pyocyaneus are had inhibitory action, 700mg/kg gavage by luteolin 10mg/ml, the mice infecting staphylococcus aureus are had anti-infectious function, hence it is evident that reduce mortality rate.
Folium Polygoni Tinctorii: cold in nature, bitter in the mouth.GUIXIN warp, stomach warp.Heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.Belong to the heat and toxic materials clearing away medicine of classification under antipyretic.With controlling epidemic febrile disease heating, send out speckle dermexanthesis, lung-heat cough with asthma, sore throat, mumps, erysipelas, carbuncle.Containing indirubin in herb, indigo, N-phenyl-2-naphthylamine, cupreol, laccerol, its aerial parts containing Kaempferol-glucopyanoside, 3,5,4 '-trihydroxy-6,7-methylene-dioxy flavone-3-O-β-D-glucopyanoside.Additionally, also containing color ammonia ketone.
Ilex purpurea Hassk.[I.chinensis Sims: cool in nature is bitter in the mouth, puckery.Return lung meridian, large intestine channel, bladder warp.Heat-clearing and toxic substances removing, blood stasis dispelling of subsiding a swelling.Belong to the heat and toxic materials clearing away medicine of antipyretic subordinate classification.With controlling cough due to lung-heat, laryngopharynx swelling and pain, dysentery, hypochondriac pain, pyretic stranguria；Externally treating burns and scalds, skin ulcer.Folium Ilicis Purpureae is mainly composed of Ilicis Purpureae Triterpene Glycosides A, that is 3 β-O-(β-D-xylopyranosyl) siaresinolic acid and Ilicis Purpureae Triterpene Glycosides B methyl ester that is 3 β-O-(β-D-xylopyranosyl) pomolic acid methyl ester.Additionally, also containing protocatechuic acid, protocatechualdehyde, ursolic acid, tannin, flavonoid glycoside and saccharide etc..
Herba Scutellariae Barbatae: acrid in the mouth, hardship, cold in nature.Return lung meridian, Liver Channel, kidney channel.Heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, diuresis.Belong to the heat and toxic materials clearing away medicine in antipyretic subordinate, there is diuresis, the excited effect breathed and antidote against snake bite.With controlling advanced schistosomiasis ascites, cirrhotic ascites, venom, furuncle carbuncle.Main containing alkaloid, flavonoid glycoside, saponin, aminoacid, polysaccharide；Secondary to inulin.
Folium Nandinae domesticae: cold in nature, bitter in the mouth.Gui Jingwu.Clearing away heat-damp and promoting diuresis, pathogenic fire purging, removing toxic substances.Belong to the heat clearing and fire purging medicine of classification under antipyretic.Cure mainly cough due to lung-heat, pertussis, pyretic stranguria, hematuria, conjunctival congestion and swelling pain, carbuncle sore, scrofula.Main containing compositions such as magnoflorine, vitamin C, Fructus Nandinae Domesticae cyanogen glycosides, amentoflavone, Fructus Nandinae Domesticae glycosides A.Flos Plumeriae Acutifoliae: property hardship sweet, micro-, taste is put down.Return lung meridian, large intestine channel.Eliminating damp-heat, bowel relieving antidiarrheal, relieving cough and resolving phlegm.Belonging to the heat clearing and fire purging medicine of antipyretic subordinate, rabbit, Cavia porcellus, cat, mice are had local numb and nonspecific spasmolysis by Aqueous extracts.Brown plumericin in leaf, stem can suppress growth of bacillus tubercle.With controlling diarrhea due to damp-heat, dysentery stomachache.Containing 27 kinds of volatile ingredients such as a-terpineol, nerolidol；Plumieric acid and glycoside.The peel of stem of Flos Plumeriae Acutifoliae is containing plumieride；Root is containing plumericin, isoplumericin etc.；Leaf is containing Kaempferol Glucoside, Quercetin Glucoside；Containing lupeol and acetas thereof in milk.
Folium Nelumbinis: property is put down, bitter in the mouth.Return Liver Channel, spleen channel, stomach warp.Clearing away summer-heat and eliminating dampness, sending up the lucid YANG, cooling blood for hemostasis.Belong to the heat removing and blood cooling medicine of classification under antipyretic.Tell nosebleed for summer-heat excessive thirst, diarrhea due to summer heat and dampness, diarrhea due to hypofunction of the spleen, heat in blood, metrorrhagia of having blood in stool, burnt FOLIUM NELUMBINIS astringent therapy removing stasis to stop bleeding, for hemorrhage and puerperal blood faints.
Herba Saxifragae: cold in nature, mildly bitter flavor.Return lung meridian, stomach warp.Tool dispel the wind, heat clearing away, blood-cleaning detoxifying effect.Belong to the heat removing and blood cooling medicine of antipyretic subordinate classification.With controlling rubella, eczema, otitis media, erysipelas, cough haematemesis, lung abscess, metrorrhagia, haemorrhoids.Containing Quercitroside, Quercetin, 5-glucoside, Bergeninum, gallic acid, protocatechuic acid, succinic acid, first class Fumaric acid, Quercetin, chlorogenic acid, Folium Vaccinii vitis-idaeae powder glycosides and volatile oil.Bacillus proteus, Bacillus typhi, dysentery bacterium, staphylococcus aureus, bacillus pyocyaneus there is inhibitory action in various degree.
Herba mesonae chinensis: cold in nature is sweet in the mouth, light.Gui Jingwu.Relieve summer heat quench one's thirst, heat-clearing and toxic substances removing.Belong to the heat removing and blood cooling medicine of antipyretic subordinate classification.With controlling heatstroke fire osteodynia thirsty, wet；Closely have for diabetes, hypertension.Containing compositions such as flavonoid, phenols, terpenoid, tannin, aminoacid, polysaccharide, therefrom separate and obtain oleanolic acid, Quercetin.According to another report, this product being made antihypelipidemic preparation, the live part of blood sugar lowering is water soluble part.
Radix Rehmanniae: Radix Rehmanniae: clearing away heat and cooling blood, yin nourishing, promote the production of body fluid.Radix Rehmanniae: clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis.Belong to the heat removing and blood cooling medicine of antipyretic subordinate classification.Conventional control calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, hematemesis and epistaxis, send out speckle dermexanthesis.Radix Rehmanniae: for consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, spit blood, epistaxis, laryngopharynx swelling and pain.Containing Martynoside., dihydro catalpol glycosides, aucubin, catalpol glycosides and several amino acids.Pharmacological evaluation confirms, has the effects such as blood sugar lowering, hemostasis, anti-disseminated inravascular coagulation and anti inflammatory immunity.
Flos Hibisci: cool in nature, sweet in the mouth, hardship.Return spleen channel, lung meridian, Liver Channel.Clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Belong to the heat removing and blood cooling medicine of classification under antipyretic.Cure mainly hemorrhoidal hamorrhage and rush down blood, red white dysentery, bleeding hemorrhoids, cough due to lung-heat, spitting of blood, leucorrhea, furuncle carbuncle, scald.To pathogenic escherichia coli and dysentery bacterium all without obvious effect；Can killing parasites for relieving itching, wash one's face with it, it is possible to treatment scalp itch；Animal experiment proves that its pollen has sensitization.Cortex Lycii: cold in nature, sweet in the mouth.Return lung meridian, Liver Channel, kidney channel.Removing heat from blood is except steaming, lung heat clearing pathogenic fire reducing.Belong to the heat removing and blood cooling medicine of antipyretic subordinate classification.With controlling deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis, interior-heat are quenched one's thirst.Containing cinnamic acid and substantial amounts of aldehydes matter etc..Low grade fever that tuberculosis and chronic inflammatory disease are caused, hectic fever etc. have better effects, and can improve thirsty and reduce the symptom such as blood glucose, blood pressure.
Cortex Dictamni: cold in nature, bitter in the mouth.Return spleen channel, stomach warp.Heat clearing and damp drying, removing toxic substances of dispeling the wind.Belong to the heat clearing and dampness removing medicine of classification under antipyretic.Treat the diseases such as damp and hot sore, impetigo, eczema, rubella, scabies, skin ulcer leprosy, rheumatism numbness, jaundice dark coloured urine.Suitable amount used externally, pan-fried soup is washed or levigation applies.Containing compositions such as dictamine .beta.-fagarine, ketone, obacunone.Various skin fungus is all had inhibitory action in various degree by infusion；The rabbit that temperature is stung heating by infusion has refrigeration function；Cellular immunization and humoral immunization all there are is inhibitory action, and is not resulted in spleen atrophy；This product polysaccharide can also improve the phagocytic function of reticuloendothelial system；Isolated frog heart is had excitation by dictamine, and cardiac muscular tension can be made to increase, and in vitro rabbit ear blood vessel has obvious contraction .gamma.-fagarine energy arrhythmia；In addition this product can shorten clotting time, and lax blood vessel, rat is had antifertility, decapacitation by ketone, and dictamine has Anticancer Activity in vitro.Gynesin rats gavaged LD50 is 5 g kg.
Slurry grass: clearing away heat-damp and promoting diuresis, cool the blood dissipate blood stasis, subduing swelling and detoxicating.Control and have loose bowels, dysentery, jaundice, gonorrhea, leucorrhea with red and white discharge, measles, spit blood, epistaxis, laryngopharynx swelling and pain, furuncle, carbuncle, scabies, haemorrhoids, proctoptosis, traumatic injury, burn.
Rhizoma Coptidis: pathogenic fire purging, dampness, removing toxic substances, parasite killing.Row pyretic toxicity when controlling, typhoid fever, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, and diarrhea of heat type is suffered from abdominal pain, and lung knot is pressed, and tells, is defeated in battle, hematochezia, quenches one's thirst, infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha etc..
The Radix Astragali: sweet in the mouth slightly warm in nature.Return lung, spleen, liver, kidney channel.Polishing consolidating superficial resistance, holds in the palm skin ulcer granulation promoting.Curing mainly body void spontaneous perspiration, chronic diarrhea, proctoptosis, uterine prolapse, chronic nephritis, body is impractical swollen, chronic ulcer, open sore part disunion of a specified duration.
Radix Rubiae: removing heat from blood and promoting blood circulation, blood stasis dispelling, stimulates the menstrual flow.For spitting blood, epistaxis, metrostaxis, traumatic hemorrhage, amenorrhea stasis blocking, arthralgia, tumbling and swelling.Cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling: this product is stopped blooding and do not stayed the stasis of blood, amenorrhea stomachache, traumatic injury hemorrhage for heat syndrome.Join Os Sepiae hemostasis power higher.
Herba Cirsii: cool in nature, sweet in the mouth, hardship.GUIXIN warp, Liver Channel.Cooling blood for hemostasis, removing blood stasis to reduce swelling.Belong to the blood-cooling hemostatic of hemorrhage subordinate classification.External: smash and apply or decoct washing.With controlling haematemesis, epistaxis, hematuria, have blood in stool, metrostaxis, traumatic hemorrhage, jaundice, carbuncle sore tumefacting virus etc..There is anastalsis.PARA FORMALDEHYDE PRILLS(91,95) arthritis has a degree of antiinflammation；Also calm, antibacterial and choleretic effect, containing choline, saponin, Catecholamine matter, and the reaction of aobvious alkaloid saponin.Water decoction has the effect of direct sympathomimetic, and the rat destroying spinal cord after fiber crops has the boosting of norepinephrine sample；Extrasomatic rabbit heart and toad heart all there is excitation.
Flos Sophorae: cold nature, bitter in the mouth.Return Liver Channel, large intestine channel.Cooling blood for hemostasis, purging liver-fire.Belong to the blood-cooling hemostatic of hemorrhage subordinate classification.By treating hematochezia, hemorrhoidal bleeding, dysentery, metrorrhagia, haematemesis, epistaxis, liver-heat conjunctival congestion, headache dizziness.Containing rutin (rutin) 10%～28%.The highest with content in alabastrum, after open, content reduces.Another containing compositions such as triterpene saponin, glucose, glucuronic acids.Pharmacological research shows, contained rutin and aglycon quercetin thereof can keep the normal tension of blood capillary, reduce its permeability, and the blood capillary hemorrhage because fragility increases can be made to recover normal elasticity.Quercetin can expand coronary vasodilator, improves myocardial circulation, strengthens contractility and the output of the heart；And reduce heart rate.There are antiinflammatory, spasmolytic and antiulcer action, and antibacterial, virus and fungus are all had inhibitory action.
Herba Bryophylli Pinnati: cold in nature is the micro-acid of taste, puckery.Return lung meridian, kidney channel.Removing toxic substances and promoting subsidence of swelling, promoting blood circulation and stopping pain, removing toxic substances and promoting tissue regeneration.Belong to the blood-cooling hemostatic of classification under hemorrhage.With controlling laryngopharynx swelling and pain, hot stomachache, diarrhea of heat type hematodiarrhoea, hemoptysis, haematemesis, acute catarrhal conjunctivitis, otitis media, carbuncle furunculosis, acute mastitis, burn due to hot liquid or fire, traumatic hemorrhage etc..Leaf containing cis-aconitic, ascorbic acid, to bean perfume (or spice) element, ferulic acid, syringic acid, caffeic acid, P-hydroxybenzoic acid and other organic acid etc..Multiple Gram-positive and gram negative bacteria are had broad-spectrum bactericidal action, multiple there is drug-fast antibacterial including what be clinically separated out.
Herba Ecliptae: cold in nature, sweet in the mouth, acid.Return kidney channel, Liver Channel.Nourishing the liver and kidney, cooling blood for hemostasis.Belong to the blood-cooling hemostatic of hemorrhage subordinate classification.Use treating the liver deficiency of the kidney yin, odontoseisis, early whitening of beard and hair, vertigo and tinnitus, soreness of the waist and knees, YinXuXueRe, haematemesis, epistaxis, hematuria, dysentery, metrostaxis, traumatic hemorrhage.Herb containing Saponin 1.32%, nicotine about 0.08%, tannin, vitamin A, ecliptine, multiple thiophene compound, wedelolactone, demethylwedelolactone.Demethylwedelolactone-7-glycoside, aerial parts Petroleum ether extraction part is containing stigmasterol, plant sterol A and β-balsam；Still containing luteolin-7-O-glycoside, plant sterol A glycoside and a kind of triterpenic acid glycoside in ethanol extraction.
Amaranthus spinosus L.: sweet, light is cool.Return stomach warp, spleen channel, large intestine channel.Clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, cooling blood for hemostasis.Belong to the blood-cooling hemostatic of hemorrhage subordinate classification.With controlling dysentery, abdominal pain due to damp-heat, bleeding hemorrhoids, nebulousurine, stranguria with blood, skin eczema.Root containing hitodesterol, mixing saponin, wherein separate sapogenin has oleanolic acid, sugar is D-Glucose and D-Glucose aldehydic acid.Stem and leaf is containing hitodesterol, hentriacontane.Have been reported that leaf is containing Microamounts of Hydrogen cyanic acid.
Radix Sanguisorbae: cold nature, bitter in the mouth, acid, puckery.Return Liver Channel, large intestine channel.Cooling blood for hemostasis, removing toxic substances sore.Belong to the blood-cooling hemostatic of hemorrhage subordinate classification.With treating hematochezia, hemorrhoidal bleeding, dysentery, metrorrhagia, burn due to hot liquid or fire, carbuncle sore tumefacting virus.Containing Radix Sanguisorbae glycosides I, Radix Sanguisorbae glycosides II, aglycon 19-Alpha-hydroxy ursolic acid.Another containing sanguisorbin A, sanguisorbin B, sanguisorbin E, aglycon ursolic acid, and the composition such as catechin.Pharmacological research, has anastalsis, and wound fluid can be made to reduce, and infection is conducive to wound tissue healing.Additionally, still have blood pressure lowering and emesis etc. to act on.
Radix Notoginseng: warm in nature, sweet in the mouth, micro-hardship.Return Liver Channel, stomach warp.Dissipating blood stasis hemostasis, subduing swelling and relieving pain.Belong to the stasis-resolving hemostatic of hemorrhage subordinate classification.With controlling spitting of blood, haematemesis, epistaxis, have blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen twinge, tumbling and swelling.Animal experiment shows, nervus centralis is had excitation by ginsenoside Rg's class, Rb class then has inhibitory action, and Radix Notoginseng total arasaponins can suppress platelet aggregation, Radix Notoginseng extract has heart tonifying, blood pressure lowering, protects the liver, antiinflammatory, reduction blood cholesterol, immunomodulating and antivirus action.It is sayed in total face, and blood and hemopoietic system have the effects such as hemostasis, antiplatelet aggregation and thrombolytic, haemolysis, hemopoietic；Cardiovascular system is had arrhythmia, atherosclerosis, anoxia enduring and shock, improves the effects such as cerebral ischemia；Nervous system is had the effect such as central nerve inhibition, analgesia；Improving immunocompetence, liver function protecting, antitumor, slow down aging, blood sugar lowering, antiinflammatory, Auto-regulator metabolism, promote growth；Toxicity is relatively low, and long-term prescription is substantially without side reaction.Main containing ginsenoside Rg1, Quercetin, acetic acid, Flos Caryophylli alkene, ginsenoside Re, leucine, 12 kinds of monomer saponins and the hemostatic compositions dencichine such as β-sitoesterol-D-Glucose glycosides, panaxytiol, arasaponin.Another containing volatile oil and various trace elements.
Catechu: cold nature is bitter in the mouth, puckery.Return lung meridian, heart channel.Removing dampness, granulation promoting, sore, hemostasis.Belong to the stasis-resolving hemostatic of hemorrhage subordinate classification.With controlling ulcer being unable to heal, eczema, aphtha, falling and flutter the pain of injury, traumatic hemorrhage.Containing catechin, epicatechin, catechotannin, lymphatic temperament, fatty oil, natural gum and wax etc..Pharmacological evaluation shows, aqueous solution can suppress the wriggling of duodenum in rabbit and small intestinal, and can promote the retrostalsis of caecum, and has anti-diarrhea effect.Staphylococcus aureus, diphtheria corynebacterium, Bacillus proteus, shigella flexneri and Bacillus typhi are all had inhibitory action by water decoction, and Common Pathogenic dermatophytes is also had inhibitory action.
Rhizoma Drynariae: warm in nature, bitter in the mouth.Return Liver Channel, kidney channel.Continue and hinder pain relieving, the kidney invigorating bone strengthening.Belong to the blood-activating analgesic of drug for invigorating blood circulation and eliminating stasis subordinate classification.With controlling lumbago due to renal deficiency, toothache, tinnitus, chronic diarrhea, traumatic injury, alopecia areata, clavus etc..Containing naringin, it is hydrolyzed to obtain Quercetin and D-Glucose and L-rhamnose, containing Rhizoma Drynariae flavanone glycosides and multiple four or five triterpenoid compound.Application thin layer ultraviolet spectrophotometry, the content measuring the naringin in Drynaria fortunei(Kunze) J.Smith rhizome is 1.00%.Pharmacological evaluation shows, naringin has and significantly promotes bone injury Healing, is one of the effective ingredient of Rhizoma Drynariae.This product can also promote the bone absorption to calcium, and improves blood calcium and serum phosphorus levels, is conducive to the healing of fracture.Rhizoma Drynariae has some improvement chondrocyte function, postpones the effect that cell regeneration becomes.Mice is had significantly analgesia and sedation by Rhizoma Drynariae flavanone.Streptomycin etc. can be prevented and treated poisoning.Clinically for osteoarthritis, preventing and treating streptomycin toxicity etc..
Rhizoma Bolbostematis: cold nature, bitter in the mouth.Return lung meridian, spleen channel.Eliminating stagnation, detumescence, removing toxic substances.Belong to medicine for removing toxic substances and promoting tissue regeneration.With controlling acute mastitis, scrofula, mastitis, lymphoid tuberculosis, chronic lymphadenitis, hypertrophic rhinitis.Containing the composition such as alkaloid, sucrose.The composition of Rhizoma Bolbostematis is different from Bulbus Fritillariae Uninbracteatae, and effect has very big-difference.Immunologic function, it has been shown that have antiinflammatory and antitumaous effect, is separately also had many-sided influence by pharmacological tests.
Red Psychotria Leaf: bitter in the mouth, cool in nature.Return through temporary nothing.Heat-clearing and toxic substances removing, detumescence and drawing out poison.Belong to medicine for removing toxic substances and promoting tissue regeneration, root, leaf: diphtheria, tonsillitis, pharyngolaryngitis, dysentery, ileotyphus, stomachache, rheumatic ostalgia；Leaf: treating swelling and pain by traumatic injury, traumatic hemorrhage, venom, sore swollen toxin, ulcer of the lower limb are controlled in external.Suitable amount used externally, pan-fried water smoking washes, grind into powder and dress, and fresh goods mashes deposited affected part.With controlling diphtheria, tonsillitis, pharyngolaryngitis, dysentery, ileotyphus, stomachache, rheumatic ostalgia.Treating swelling and pain by traumatic injury, traumatic hemorrhage, venom, sore swollen toxin, ulcer of the lower limb are controlled in external.
Calamina: property is put down, sweet in the mouth.Return Liver Channel, spleen channel.Removing toxic substances, improving acuity of vision and removing nebula, removing dampness are antipruritic, sore.Belong to medicine for removing toxic substances and promoting tissue regeneration.Only can external, be ground into fine powder during use, dress affected part or eye dripping in right amount.With control cataract, order edge red rotten, nebula film bulbar conjunctiva polyp, ulcer being unable to heal, pus are dripping, eczema, skin pruritus.Main containing zinc carbonate, still contain the ferrum of volume, aluminum, calcium, magnesium, sodium, silicon in addition, a small amount of lead, titanium, manganese etc..For treating scytitis or surface injury, both can be partly dissolved, and inhale the juice herding wound surface and restrain, and local staphylococcus can be killed again and limit its breeding, having good anti-inflammatory analgetic effect.
Herba Euphorbiae Thymifoliae: cool in nature is sour in the mouth, puckery.Gui Jingwu.Heat clearing away, removing toxic substances, dampness removing, antipruritic.Belong to the heat and toxic materials clearing away medicine of antipyretic subordinate classification.Smash and apply or decoct washing.With controlling dysentery, enteritis；Allergic dermatitis, eczema, skin pruritus, decoct washing；Acute mastitis, mashes external application.Aerial parts master is containing taraxerol, hexacosanol etc.；Herb is again containing alkaloid, hydrolysable tannin composition.
Herba Houttuyniae: acrid in the mouth, cold.Can heat-clearing and toxic substances removing, row pain detumescence treatment skin ulcer, promoting urination to remove dampness, invigorating the stomach and promoting digestion.With controlling excess-heat, pyretic toxicity, damp, disease heat be suffer from lung abscess, sore swollen toxin, hemorrhoidal hemorrhage, retention of heat in the spleen and stomach etc..
The present invention is with heat-clearing and toxic substances removing, and expelling pus and promoting granulation is the rule for the treatment of, and the combination of multiple medical material is collaborative, it is mainly used in replenishing and activating blood, powder detoxifcation, resolving heat and reducing pathogenic fire, inducing diuresis to remove edema, convergence anticorrosion, dredging collateral eases pain, and alleviating distention in middle-JIAO is regulated the flow of vital energy, regulate internal organs negative and positive, promoting flow of QI and blood, improves immunity of organisms, and pain that shoulder neck is had a pain in the leg, sores ulceration of skin disease have significant therapeutic effect.
Clinical observation:
(1) clinical data
453 examples in 2010 so far, are takeed on the patient that neck has a pain in the leg bitterly, sores ulceration of skin is sick and are carried out clinical observation treatment by the present inventor.
(2) Therapeutic Method
Prepared ointment or powder are externally applied to affected part, every day two to three times.Calculating treatment time, patients with mild application about 7～30 days according to conditions of patients weight, severe case even applies and can fully recover for 30～60 days.
(3) curative effect determinate standard
Criterion of therapeutical effect is with reference to criterion of therapeutical effect relevant in " disease of tcm judgement criterion of therapeutical effect ".
Cure: clinical symptoms all disappears, and lab testing is normal.
Effective: clinical symptoms disappears substantially, test chamber checks that each index of correlation is close to normal level.
Effective: clinical symptom relief, test chamber checks that each index of correlation makes moderate progress, and sign has improvement.
Invalid: clinical symptoms is without being clearly better or increasing the weight of.
(4) clinical effectiveness
Clinical cure 370 example (81.68%), effective 59 examples (13.02%), effective 21 examples (4.64%), invalid 3 examples (0.66%), total effective rate is 99.34%.
The present invention prepares simply, good absorbing effect, and duration of efficacy is long, evident in efficacy, has no side effect, and safety is high, and production cost is low, is conducive to sufferer to alleviate condition of illness in time.
(4) detailed description of the invention
Embodiment 1:
Stringing GUCAO 15g, Folium Polygoni Tinctorii 16g, Ilex purpurea Hassk.[I.chinensis Sims 12g, Herba Scutellariae Barbatae 10g, Folium Nandinae domesticae 11g, Flos Plumeriae Acutifoliae 11g, Folium Nelumbinis 10g, Herba Saxifragae 10g, Herba mesonae chinensis 12g, Radix Rehmanniae 10g, Flos Hibisci 12g, Cortex Lycii 10g, Cortex Dictamni 10g, slurry grass 10g, Rhizoma Coptidis 12g, Radix Astragali 12g, Radix Rubiae 10g, Herba Cirsii 10g, Flos Sophorae 12g, Herba Bryophylli Pinnati 10g, Herba Ecliptae 12g, Amaranthus spinosus L. 12g, Radix Sanguisorbae 11g, Radix Notoginseng 12g, catechu 13g, Rhizoma Drynariae 11g, Rhizoma Bolbostematis 12g, Red Psychotria Leaf 12g, Calamina 10g, Herba Euphorbiae Thymifoliae 10g, Herba Houttuyniae 10g, above-mentioned raw materials is cleaned up, unguentum is made by conventional method.
Usage and dosage: prepared ointment or powder are externally applied to affected part, every day two to three times.
Embodiment 2:
Stringing GUCAO 26g, Folium Polygoni Tinctorii 29g, Ilex purpurea Hassk.[I.chinensis Sims 26g, Herba Scutellariae Barbatae 25g, Folium Nandinae domesticae 25g, Flos Plumeriae Acutifoliae 26g, Folium Nelumbinis 26g, Herba Saxifragae 25g, Herba mesonae chinensis 29g, Radix Rehmanniae 28g, Flos Hibisci 29g, Cortex Lycii 26g, Cortex Dictamni 26g, slurry grass 26g, Rhizoma Coptidis 26g, Radix Astragali 25g, Radix Rubiae 25g, Herba Cirsii 24g, Flos Sophorae 23g, Herba Bryophylli Pinnati 25g, Herba Ecliptae 25g, Amaranthus spinosus L. 26g, Radix Sanguisorbae 26g, Radix Notoginseng 29g, catechu 29g, Rhizoma Drynariae 25g, Rhizoma Bolbostematis 26g, Red Psychotria Leaf 28g, Calamina 28g, Herba Euphorbiae Thymifoliae 25g, Herba Houttuyniae 28g, above-mentioned raw materials is cleaned up, unguentum is made by conventional method.
Usage and dosage: prepared ointment or powder are externally applied to affected part, every day two to three times.
Embodiment 3:
Stringing GUCAO 21g, Folium Polygoni Tinctorii 22g, Ilex purpurea Hassk.[I.chinensis Sims 21g, Herba Scutellariae Barbatae 19g, Folium Nandinae domesticae 18g, Flos Plumeriae Acutifoliae 21g, Folium Nelumbinis 20g, Herba Saxifragae 20g, Herba mesonae chinensis 21g, Radix Rehmanniae 22g, Flos Hibisci 21g, Cortex Lycii 20g, Cortex Dictamni 21g, slurry grass 21g, Rhizoma Coptidis 19g, Radix Astragali 19g, Radix Rubiae 20g, Herba Cirsii 18g, Flos Sophorae 16g, Herba Bryophylli Pinnati 19g, Herba Ecliptae 21g, Amaranthus spinosus L. 21g, Radix Sanguisorbae 20g, Radix Notoginseng 20g, catechu 22g, Rhizoma Drynariae 18g, Rhizoma Bolbostematis 19g, Red Psychotria Leaf 21g, Calamina 22g, Herba Euphorbiae Thymifoliae 18g, Herba Houttuyniae 17g, above-mentioned raw materials is cleaned up, unguentum is made by conventional method.
Usage and dosage: prepared ointment or powder are externally applied to affected part, every day two to three times.

Claims (3)

  1. null1. a treatment shoulder neck has a pain in the leg bitterly、The Chinese medicine plaster that sores ulceration of skin is sick，It is characterized by，It is made up of the raw material of following parts by weight: Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 15g-26g，Folium Polygoni Tinctorii 16g-29g，Ilex purpurea Hassk.[I.chinensis Sims 12g-26g，Herba Scutellariae Barbatae 10g-25g，Folium Nandinae domesticae 11g-25g，Flos Plumeriae Acutifoliae 11g-26g，Folium Nelumbinis 10g-26g，Herba Saxifragae 10g-25g，Herba mesonae chinensis 12g-29g，Radix Rehmanniae 10g-28g，Flos Hibisci 12g-29g，Cortex Lycii 10g-26g，Cortex Dictamni 10g-26g，Slurry grass 10g-26g，Rhizoma Coptidis 12g-26g，Radix Astragali 12g-25g，Radix Rubiae 10g-25g，Herba Cirsii 10g-24g，Flos Sophorae 12g-23g，Herba Bryophylli Pinnati 10g-25g，Herba Ecliptae 12g-25g，Amaranthus spinosus L. 12g-26g，Radix Sanguisorbae 11g-26g，Radix Notoginseng 12g-29g，Catechu 13g-29g，Rhizoma Drynariae 11g-25g，Rhizoma Bolbostematis 12g-26g，Red Psychotria Leaf 12g-28g，Calamina 10g-28g，Herba Euphorbiae Thymifoliae 10g-25g，Herba Houttuyniae 10g-28g.
  2. null2. one according to claim 1 treat shoulder neck have a pain in the leg pain、The Chinese medicine plaster that sores ulceration of skin is sick，It is characterized by，It is made up of the raw material of following parts by weight: Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 15g，Folium Polygoni Tinctorii 16g，Ilex purpurea Hassk.[I.chinensis Sims 12g，Herba Scutellariae Barbatae 10g，Folium Nandinae domesticae 11g，Flos Plumeriae Acutifoliae 11g，Folium Nelumbinis 10g，Herba Saxifragae 10g，Herba mesonae chinensis 12g，Radix Rehmanniae 10g，Flos Hibisci 12g，Cortex Lycii 10g，Cortex Dictamni 10g，Slurry grass 10g，Rhizoma Coptidis 12g，Radix Astragali 12g，Radix Rubiae 10g，Herba Cirsii 10g，Flos Sophorae 12g，Herba Bryophylli Pinnati 10g，Herba Ecliptae 12g，Amaranthus spinosus L. 12g，Radix Sanguisorbae 11g，Radix Notoginseng 12g，Catechu 13g，Rhizoma Drynariae 11g，Rhizoma Bolbostematis 12g，Red Psychotria Leaf 12g，Calamina 10g，Herba Euphorbiae Thymifoliae 10g，Herba Houttuyniae 10g.
  3. 3. a kind for the treatment of according to claim 1 takes on the Chinese medicine plaster that neck has a pain in the leg bitterly, sores ulceration of skin is sick, it is characterised in that: described Chinese medicine is unguentum or powder.
CN201610147813.2A 2016-03-16 2016-03-16 Chinese herbal plaster for treating shoulder, neck and leg pain and skin and external diseases Pending CN105726777A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109663020A (en) * 2019-02-25 2019-04-23 广西中医药大学 A kind of Yao medicinal composition that treating pruritus and its application
CN115444855A (en) * 2022-10-24 2022-12-09 牡丹江医学院附属红旗医院 Pharmaceutical composition for treating ulcerative colitis and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102178874A (en) * 2010-12-14 2011-09-14 史志辉 Preparation method of Chinese medicinal tablet for treating skin diseases
CN102205068A (en) * 2011-05-12 2011-10-05 倪惠君 Medicament for treating chronic ulcerative colitis and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102178874A (en) * 2010-12-14 2011-09-14 史志辉 Preparation method of Chinese medicinal tablet for treating skin diseases
CN102205068A (en) * 2011-05-12 2011-10-05 倪惠君 Medicament for treating chronic ulcerative colitis and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109663020A (en) * 2019-02-25 2019-04-23 广西中医药大学 A kind of Yao medicinal composition that treating pruritus and its application
CN115444855A (en) * 2022-10-24 2022-12-09 牡丹江医学院附属红旗医院 Pharmaceutical composition for treating ulcerative colitis and application thereof

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