CN109663020A - A kind of Yao medicinal composition that treating pruritus and its application - Google Patents
A kind of Yao medicinal composition that treating pruritus and its application Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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Abstract
The invention belongs to national medicine fields, and in particular to a kind of Yao medicinal composition for treating pruritus and application, it is solved the technical issues of be to provide a kind of Yao medicinal composition for treat due to autumn, winter climate it is dry caused by cutaneous pruritus.The weight proportion of Yao medicinal composition bulk pharmaceutical chemicals of the present invention are as follows: fresh kiss-me 10-50 parts, 10-30 parts of boxthorn root, 10-30 parts of Chinese mahonia.It may be implemented that there is significant therapeutic effect in particular for geroderma itch to the therapeutic effect in autumn, the dry caused cutaneous pruritus of winter climate using Yao medicinal composition provided by the invention.The drug in treatment autumn, skin pruritus in winter disease prepared by the Yao medicinal composition has the advantages that short treating period, quick, adverse reaction is few, drug effect can be played persistently.
Description
Technical field
The invention belongs to national medicine fields, and in particular to a kind of Yao medicinal composition for treating pruritus and its application.
Background technique
The described pruritus of Chinese medicine nationality doctor, also known as pruritus due to wind pathogen, pruritus, universal eczema etc., the pruitus of similar doctor trained in Western medicine meaning
Disease." surgery card controls pandect " volume four: " itch all over, has no sore scabies, scratches more than.", so pruritus refers to itch all over, and
Without sore scabies, what is scratched is the cacesthesia skin disease mainly showed incessantly.Pruritus is damaged without primary cutaneous, with conscious skin
Paroxysmal itch, often occurring the secondary skin lesion such as scratch, scab, pigmentation and lichenification after scratching is Clinical symptoms.Face
Limitation and two kinds of hair property general can be divided on bed, limitation person is most with private parts, perianal itch；General hair property person, then it is how general
Send out whole body.This disease male morbidity is in the majority, is more common in old and person between twenty and fifty, geroderma itch disease incidence is more than 10%；This disease
It is apt to occur in Qiu Mo and winter, minority can also fall ill summer.From the Chinese point of view, this disease is wind disease, by wind, wet, hot is accumulate in flesh
Skin, must not be caused by catharsis；Or blood deficiency and sthenic liver-energy, raw weathering is dry, failure of skin and muscle to be nourished and obtain." General Treatise on the Cause and Symptoms of Diseases ": " pruritus due to wind pathogen person is body
Empty wind-engaging, wind enters space between skin and muscles, mutually fights with qi and blood, and is all to and between skin.Perverse trend is micro-, cannot impact for pain, therefore but itch
?." pruritus due to wind pathogen because natural disposition intolerant to, accumulate in blood-head, exopathogen invasion, cause blood hot air wind producing and itch；Or because of sick long, old and frail, qi and blood
Virtual loss, ailment said due to cold or exposure take advantage of a weak point in opponent's defence it is outer attacks, wind formation from blood deficiency, failure of skin and muscle to be nourished and itch；Or be eating and drinking without temperance, the pungent toast of addiction is rich, pure wine is greasy, damage
The impairment of the spleen, damp and hot interior life, with the passing of time change hot air wind producing, it is interior must not catharsis, must not reach thoroughly outside, it is strongly fragrant to be sent out in skin；Or by feelings will internal injury,
Fire-syndrome caused by the disorders of the five emotions accumulates in blood-head, changes the dynamic wind of heat and forms.Pruritus patient itch all over, lighter night on daytime is particularly acute, often because of itch
And it causes uneasy sleeping at night, receive poor, lassitude.Although clinically the cause of disease is different for pruritus, to sum up nothing more than blood-head, blood
Empty, blood stasis etc, so as to cause 3 kinds of blood hot air wind producing card, syndrome of wind and dryness due to blood deficiency, blood-stasis syndrome card types.Traditional Chinese medicine according to " control wind elder generation
Control blood, blood wind is from going out " scheduling theory, go respectively in treatment pruritus enriched blood with cool blood enriching yin, blood-nourishing, the treatments side such as activating blood circulation
Method.
It is 10%~50% that, which there are studies have shown that the elderly's pruitus illness rate in foreign countries, the frequency of age bigger pruitus
Rate and degree are higher, and in China, senile skin pruritus illness rate is up to 10% or more.Someone is to 1556 trouble in certain home for destitute
Person carries out inspection discovery, has 1002 with itch and related disease, illness rate is up to 64.4%；There are also studies have shown that Jinan armies
1286 60 years old and the above the elderly person in middle and old age property pruritus are up to 42.4% in the second sanatorium of area Qingdao, it is seen that senile skin
Skin pruritus disease incidence is high, seriously affects the healthy living of the elderly.In the treatment of pruritus, doctor trained in Western medicine is mostly with oral anti-allergy
There is the problems such as easily causing drug resistance and big side effect because the effect of its antipruritic is single in medicine and local topical glucocorticoid treatment.
Chinese medicine is then frequently with oral medicinal herb, bloodletting threapy and cupping etc., and compared with doctor trained in Western medicine, the safety of Chinese medicine treatment is higher, without obvious
Adverse reaction, but there is not yet the longer treatment pruritus of curative effect special efficacy Chinese patent drug or Chinese prescription, most recipe, which exist, to be controlled
Treat the disadvantage that the time is long, duration of efficacy is short.The Yao nationality is the nationality of a good health and a long life, and the autonomous county, the Yao nationality of nearly half is commented
For the township of national longevity, Yao Autonomous County of Bama is then cited as the township of world's longevity, and long-lived reason essentially consists in the Yao nationality and exists
There is unique advantage in health care and disease treatment, wherein skin disease, gynaecological disease etc. are Yao nationality medicine advantage disease, particularly with skin
The treatment of skin relevant disease such as nettle rash, pruritus etc. is especially good at.High in view of pruritus disease incidence, cure rate is low, and the course of disease is long, easily
Recurrence, it is larger for the damage of patient's body and mind, and it is directed to the respective deficiency of above-mentioned integrative therapy, present invention applicant collects precious jade
Race's folk remedy through advanced optimizing, and determines that it has short treating period, quick, adverse reaction for pruritus according to clinical verification
Less, the endurable treatment advantage of drug effect.
Summary of the invention
In view of this, one of the objects of the present invention is to provide a kind of Yao medicinal composition for treating pruritus, the composition root
According to the theory of traditional Chinese medical science of " control wind and first control blood, blood wind from go out ", for the illness mechanism of blood hot air wind producing, blood-deficiency and wind-dry, stagnation of blood stasis,
Enriched blood using cool blood enriching yin, blood-nourishing, the treatment concept of activating blood circulation and propose.
To achieve the above object, the invention adopts the following technical scheme:
A kind of Yao medicinal composition for treating pruritus, is made of following material component: fresh kiss-me, boxthorn root, Chinese mahonia.
Chinese mahonia in the Yao medicinal composition of the treatment pruritus, including mahonia fortuneiFedde and/or north Jiang Shi great function
Labor and/or fruitlet Chinese mahonia and/or mahonia bealei.
It is described treatment pruritus Yao medicinal composition in Chinese mahonia medicinal part include root and/or stem and/or leaf and/or
Colored and/or fruit.
Preferably, the Yao medicinal composition of the treatment pruritus, is made of following precious jade medicine component: fresh kiss-me by weight
10-50 parts, 10-30 parts of boxthorn root, 10-30 parts of Chinese mahonia.
It is further preferred that the Yao medicinal composition of the treatment pruritus, is made of following precious jade medicine component: fresh by weight
20-40 parts of kiss-me, 15-25 parts of boxthorn root, 15-25 parts of Chinese mahonia.
It is further preferred that the Yao medicinal composition of the treatment pruritus, is made of following precious jade medicine component by weight:
30 parts of fresh kiss-me, 20 parts of boxthorn root, 20 parts of Chinese mahonia.
In above-mentioned Yao medicinal composition:
The parts by weight can be unit of weight well known to the field of medicaments such as μ g, mg, g, kg, be also possible to its multiple, such as
1/10,1/100,10 times, 100 times etc..
The second purpose of the present invention is to provide a kind of applications of the Yao medicinal composition for the treatment of pruritus, are specially preparing
Treat the application in pruritus drug.The Yao medicinal composition for the treatment of pruritus of the present invention is that Yao nationality area Popular Utilization is extremely wide
Empirical formula, confirm that the composition of the treatment pruritus has that short treating period, quick, adverse reaction is few, drug effect is endurable controls
Treat advantage.
To achieve the above object, the present invention uses following scheme:
The drug of the treatment pruritus can be any pharmaceutically acceptable dosage form.
Further, the drug of the treatment pruritus further includes pharmaceutical acceptable carrier and/or auxiliary agent.
The pharmaceutically acceptable dosage form includes Yao medicinal composition of the invention and optional one or more pharmaceutically may be used
Carrier, diluent or the excipient of receiving.Term " pharmaceutically acceptable " used in the present invention refer to such compound,
Raw material, composition and/or dosage form, they within the scope of reasonable medical judgment, be suitable for contacted with patient tissue and without excessive
Toxicity, irritation, allergy or other problems relative to a reasonable benefit/risk ratio and complication, and effective for
Given application.
Key problem in technology point of the invention is:
1. the present invention is the Chinese medicine and the Yao nationality medicine interpretation of the cause, onset and process of an illness according to pruritus, overcomes the shortage of prior art and propose.The present invention mentions
The raw material of the Yao medicinal composition of confession forms: fresh kiss-me, boxthorn root, Chinese mahonia.The present invention according to pruritus by blood-head, the deficiency of blood or
The characteristics of blood stasis causes, using with wind-damp dispelling, relieving itching, cooling blood and hemostasis, solution endogenous toxic material, clear interior hot kiss-me, the fire that dries is moved back
Abnormal heat, the boxthorn root of clearing lung-heat fire and heat-clearing and damp-drying drug, purging fire for removing toxin Chinese mahonia be group a recipe, to reach the mesh of dispelling wind and arresting itching
, there is good curative effect for the treatment of pruritus.
Caused by 2. Yao medicinal composition provided by the invention can be used for treating pruritus, especially Qiu Mo and winter climate drying
Geroderma itch.
3. Yao medicinal composition provided by the invention is pure natural medical preparation, without side-effects, there is heat-clearing and damp-drying drug, wind-dispelling to stop
The effect of itching can improve rapidly patient symptom.
4. show that Yao medicinal composition provided by the invention can be used for the treatment of pruritus, and prescription is simple by clinical verification,
Effect is lasting, is better than the prior art.
Specific embodiment
Illustrated embodiment is in order to which preferably the present invention will be described, but is not that the contents of the present invention are limited only to institute
For embodiment.So those skilled in the art according to foregoing invention content to embodiment carry out it is nonessential improvement and
Adjustment, still falls within protection scope of the present invention.
It elaborates below with reference to embodiment to technical solution of the present invention.
Kiss-me (Saxifraga stolonifera Curt.) is Saxifragaceae Saxifraga perennial evergreen draft
Plant has effects that dispelling wind and eliminating dampness, antipruritic anti-inflammatory, cooling blood and hemostasis, solution endogenous toxic material, clear interior heat with all herbal medicine, using fresh herb.Mainly
For treating cough due to wind-heat evil, otitis media acuta, bullous myringitis, prostatitis, eczema, rubella itch, toothache, haematemesis, lung
The diseases such as carbuncle, metrorrhagia and metrostaxis, haemorrhoids.
Boxthorn root is the root of matrimony vine of solanaceae plant Lycium chinense Mill., using fresh herb or dry use.With dry fire,
Effect of reducing the asthenic fever, clearing lung-heat fire, the wet fiery ostalgia of primary treatment, deficiency of Yin hectic fever, the diseases such as cough with lung heat.
Chinese mahonia is Berberidaceae plant mahonia fortuneiFedde Mahonia fortunei (Lindl.) Fedde or fruitlet
Chinese mahonia Mahonia bodinieri Gagnep. or north river Chinese mahonia Mahonia fordii C.K.Schneid or wealthy
The complete stool of leaf Chinese mahonia Mahonia bealie (Fort.) Carr., using fresh herb or it is dry use, have heat-clearing and damp-drying drug, purging fire for removing toxin,
Anti-inflammatory analgetic, relieving cough and reducing sputum and other effects, primary treatment osteopyrexia and fever, tuberculosis hemoptysis, bacillary dysentery, dizziness and tinnitus, throat are swollen
The diseases such as pain.
Embodiment 1
The present embodiment provides a kind of Yao medicinal composition for treating pruritus, composition: 10 parts of fresh kiss-me, boxthorn root 20
Part, 20 parts of mahonia fortuneiFedde (root and stem mixture).
Preparation method: weighing each raw medicinal material according to above-mentioned parts by weight, and raw medicinal material gross weight measures 100g, is decocted in water for oral dose, and 5 days
It is as a treatment course.
Patient take after effect:
Case 1: patient Tang XX, male 65 years old, suffer from pruritus 10 years, take within 2016 2 courses for the treatment of, and Morbidity control returns for 2017
It visits, does not recur.
Case 2: what XX of patient, male 35 years old, suffer from pruritus 6 years, take within 2017 1 course for the treatment of, and Morbidity control is paid a return visit for 2018,
It does not recur.
Case 3: what XX of patient, male 55 years old, suffer from pruritus 10 years, take within 2017 1 course for the treatment of, and Morbidity control returns for 2018
It visits, does not recur.
Embodiment 2
The present embodiment provides a kind of Yao medicinal composition for treating pruritus, composition: 50 parts of fresh kiss-me, boxthorn root 25
Part, 25 parts of mahonia fortuneiFedde (leaf and flower and fruit mixture).
Application method: each raw medicinal material is weighed according to above-mentioned parts by weight, raw medicinal material gross weight measures 1kg, with 30L boiling
20min filters the dregs of a decoction and takes liquid medicine external application bathing, bathing time 20min, 7 days as one therapeutic course.
Effect after patient's use:
Case 1: patient Lee XX, male 63 years old, suffer from pruritus 5 years, use within 2016 3 courses for the treatment of, and Morbidity control is paid a return visit for 2017,
It does not recur.
Case 2: patient thanks to XX, and male 70 years old, suffers from pruritus 12 years, uses within 2016 3 courses for the treatment of, and Morbidity control returns for 2017
It visits, does not recur.
Case 3: patient Zhu XX, male 50 years old, suffer from pruritus 5 years, use within 2016 2 courses for the treatment of, and Morbidity control is paid a return visit for 2017,
It does not recur.
Embodiment 3
The present embodiment provides a kind of Yao medicinal composition for treating pruritus, composition: 20 parts of fresh kiss-me, boxthorn root 15
Part, 15 parts of fruitlet Chinese mahonia (leaf and flower and fruit mixture).
Preparation method: weighing each raw medicinal material according to above-mentioned parts by weight, and raw medicinal material gross weight measures 100g, is decocted in water for oral dose, and 5 days
It is as a treatment course.
Patient take after effect:
Case 1: the white XX of patient, female 59 years old, suffer from pruritus 4 years, take within 2017 1 course for the treatment of, and Morbidity control is paid a return visit for 2018,
It does not recur.
Case 2: patient Feng XX, male 75 years old, suffer from pruritus 13 years, take within 2016 2 courses for the treatment of, and Morbidity control returns for 2017
It visits, does not recur.
Case 3: patient ox XX, male 65 years old, suffer from pruritus 11 years, take within 2016 2 courses for the treatment of, and Morbidity control returns for 2017
It visits, does not recur.
Embodiment 4
The present embodiment provides a kind of Yao medicinal composition for treating pruritus, composition: 45 parts of fresh kiss-me, boxthorn root 25
Part, 30 parts of the fresh complete stool of fruitlet Chinese mahonia.
Application method: each raw medicinal material is weighed according to above-mentioned parts by weight, raw medicinal material gross weight measures 1kg, with 30L boiling
20min filters the dregs of a decoction and takes liquid medicine external application bathing, bathing time 20min, 7 days as one therapeutic course.
Effect after patient's use:
Case 1: patient Yao XX, female 55 years old, suffer from pruritus 3 years, use within 2017 2 courses for the treatment of, and Morbidity control is paid a return visit for 2018,
It does not recur.
Case 2: Guo patient XX, male 65 years old, suffer from pruritus 7 years, use within 2016 3 courses for the treatment of, and Morbidity control is paid a return visit for 2017,
It does not recur.
Case 3: patient Yan XX, male 45 years old, suffer from pruritus 3 years, use within 2017 2 courses for the treatment of, and Morbidity control is paid a return visit for 2018,
It does not recur.
Embodiment 5
The present embodiment provides a kind of Yao medicinal composition for treating pruritus, composition: 25 parts of fresh kiss-me, boxthorn root 10
Part, northern 15 parts of river Chinese mahonia (leaf and flower and fruit mixture).
Preparation method: weighing each raw medicinal material according to above-mentioned parts by weight, and raw medicinal material gross weight measures 100g, is decocted in water for oral dose, and 5 days
It is as a treatment course.
Patient take after effect:
Case 1: patient Lee XX, male 63 years old, suffer from pruritus 10 years, take within 2016 2 courses for the treatment of, and Morbidity control returns for 2017
It visits, does not recur.
Case 2: XX when patient, male 62 years old, suffer from pruritus 6 years, take within 2016 2 courses for the treatment of, and Morbidity control is paid a return visit for 2017,
It does not recur.
Case 3: patient opens XX, and male 67 years old, suffers from pruritus 10 years, takes within 2017 2 courses for the treatment of, and Morbidity control returns for 2018
It visits, does not recur.
Embodiment 6
The present embodiment provides a kind of Yao medicinal composition for treating pruritus, composition: 40 parts of fresh kiss-me, boxthorn root 30
Part, northern fresh 25 parts of complete stool of Chinese mahonia of river.
Application method: each raw medicinal material is weighed according to above-mentioned parts by weight, raw medicinal material gross weight measures 0.95kg, with 30L water
20min is boiled, the dregs of a decoction is filtered and takes liquid medicine external application bathing, bathing time 20min, 7 days as one therapeutic course.
Effect after patient's use:
Case 1: the high XX of patient, female 65 years old, suffer from pruritus 13 years, use within 2016 3 courses for the treatment of, and Morbidity control returns for 2017
It visits, does not recur.
Case 2: the high XX of patient, male 85 years old, suffer from pruritus 17 years, use within 2016 3 courses for the treatment of, and Morbidity control returns for 2018
It visits, does not recur.
Case 3: patient king XX, male 45 years old, suffer from pruritus 5 years, use within 2016 2 courses for the treatment of, and Morbidity control is paid a return visit for 2017,
It does not recur.
Embodiment 7
The present embodiment provides a kind of Yao medicinal composition for treating pruritus, composition: 35 parts of fresh kiss-me, boxthorn root 15
Part, 10 parts of mahonia bealei (flowers and fruits mixture).
Preparation method: weighing each raw medicinal material according to above-mentioned parts by weight, and raw medicinal material gross weight measures 120g, is decocted in water for oral dose, and 5 days
It is as a treatment course.
Patient take after effect:
Case 1: patient opens XX, and male 60 years old, suffers from pruritus 5 years, takes within 2016 2 courses for the treatment of, and Morbidity control is paid a return visit for 2017,
It does not recur.
Case 2: patient opens XX, and female 66 years old, suffers from pruritus 8 years, takes within 2016 2 courses for the treatment of, and Morbidity control is paid a return visit for 2017,
It does not recur.
Case 3: patient side XX, male 65 years old, suffer from pruritus 10 years, take within 2017 2 courses for the treatment of, and Morbidity control returns for 2018
It visits, does not recur.
Embodiment 8
The present embodiment provides a kind of Yao medicinal composition for treating pruritus, composition: it is fresh tiger 30 parts of ear, 20 parts of boxthorn root,
20 parts of the fresh complete stool of mahonia bealei.
Application method: each raw medicinal material is weighed according to above-mentioned parts by weight, raw medicinal material gross weight measures 1.4kg, with 30L boiling
20min filters the dregs of a decoction and takes liquid medicine external application bathing, bathing time 20min, 7 days as one therapeutic course.
Effect after patient's use:
Case 1: patient relies XX, and male 64 years old, suffers from pruritus 10 years, uses within 2016 2 courses for the treatment of, and Morbidity control returns for 2017
It visits, does not recur.
Case 2: the old XX of patient, male 69 years old, suffer from pruritus 10 years, use within 2017 3 courses for the treatment of, and Morbidity control returns for 2018
It visits, does not recur.
Case 3: patient Zhu XX, male 63 years old, suffer from pruritus 9 years, use within 2016 2 courses for the treatment of, and Morbidity control is paid a return visit for 2017,
It does not recur.
Finally, it is stated that the above examples are only used to illustrate the technical scheme of the present invention and are not limiting, although referring to compared with
Good embodiment describes the invention in detail, those skilled in the art should understand that, it can be to skill of the invention
Art scheme is modified or replaced equivalently, and without departing from the objective and range of technical solution of the present invention, should all be covered at this
In the scope of the claims of invention.
Claims (10)
1. a kind of Yao medicinal composition for treating pruritus, which is characterized in that calculate by weight containing following precious jade medicine component: fresh kiss-me
10-50 parts, 10-30 parts of boxthorn root.
2. the Yao medicinal composition for the treatment of pruritus according to claim 1, which is characterized in that calculate by weight by following precious jade medicine
Component composition: fresh kiss-me 10-50 parts, 10-30 parts of boxthorn root, 10-30 parts of Chinese mahonia.
3. the Yao medicinal composition for the treatment of pruritus according to claim 2, which is characterized in that calculate by weight by following precious jade medicine
Component composition: fresh kiss-me 20-40 parts, 15-25 parts of boxthorn root, 15-25 parts of Chinese mahonia.
4. the Yao medicinal composition for the treatment of pruritus according to claim 3, which is characterized in that calculate by weight by following precious jade medicine
Component composition: 30 parts of fresh kiss-me, 20 parts of boxthorn root, 20 parts of Chinese mahonia.
5. according to the Yao medicinal composition of the described in any item treatment pruritus of claim 2-4, which is characterized in that the big function of described ten
Labor includes mahonia fortuneiFedde and/or fruitlet Chinese mahonia and/or northern river Chinese mahonia and/or mahonia bealei.
6. according to the Yao medicinal composition of the described in any item treatment pruritus of claim 2-5, which is characterized in that the big function of described ten
Labor includes root and/or stem and/or leaf and/or flower and/or fruit.
7. the Yao medicinal composition of any one of the claim 1-6 treatment pruritus is preparing the application in pharmaceutical preparation.
8. application according to claim 7, which is characterized in that be treatment the effect of the pharmaceutical preparation due to autumn, winter
Pruitus caused by dry.
9. application according to claim 7, which is characterized in that the Yao medicinal composition of the treatment pruritus can be any medicine
Learn acceptable dosage form.
10. application according to claim 9, which is characterized in that the Yao medicinal composition of the treatment pruritus further includes pharmacy
Acceptable carriers and/or auxiliary agent.
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| CN112933166A (en) * | 2021-03-08 | 2021-06-11 | 霸王（广州）有限公司 | External traditional Chinese medicine composition for improving scalp sensitivity intolerance |
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