CN102973770A - Varicella-curing Chinese medicine combination and preparing method thereof - Google Patents
Varicella-curing Chinese medicine combination and preparing method thereof Download PDFInfo
- Publication number
- CN102973770A CN102973770A CN2012104671148A CN201210467114A CN102973770A CN 102973770 A CN102973770 A CN 102973770A CN 2012104671148 A CN2012104671148 A CN 2012104671148A CN 201210467114 A CN201210467114 A CN 201210467114A CN 102973770 A CN102973770 A CN 102973770A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- cortex
- fructus
- herba
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a varicella-curing Chinese medicine combination and a preparing method of the combination. The combination comprises 15-35 parts of cortex lycii radicis, 15-35 parts of cortex mori radicis, 15-35 parts of moutan bark, 12-30 parts of folium isatidis, 12-30 parts of radix scutellariae, 10-25 parts of radix isatidis, 5-12 parts of fructus forsythiae, 5-12 parts of radix scrophulariae, 5-12 parts of rhizoma anemarrhenae, 5-12 parts of fructus arctii, 4-10 parts of dried radix rehmanniae, 4-10 parts of semen plantaginis, 2-9 parts of fructus gardeniae and 1-6 parts of radix glycyrrhizae. The Chinese medicine combination can be prepared to be any kind of medicinal preparation which is acceptable clinically according to a Chinese medicine traditional preparation method. The Chinese medicine combination has the functions of heat clearing, detoxifying, blood cooling, detumescence and lung-heat clearing, and the clinical curative effect shows that the Chinese medicine combination has an exact and reliable curative effect on varicella, treats symptoms and causes, is safe in clinical use, and has no toxic and side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine composition for the treatment of chickenpox and preparation method thereof, belong to the treatment by Chinese herbs field of chickenpox.
Background technology
Chickenpox (chickenpox, varicella) is the acute infectious disease that is caused by varicella zoster virus (varicella-zoster virus, VZV) primary infection, and infectious rate is very high.Chickenpox mainly occurs in infant, and any age all can be infected chickenpox, is mainly child's multiple infectious disease, and age of onset is more with infant, has the antibody of parent with interior baby in 0～6 month, and sickness rate is lower.2～6 years old is onset peak.In the past namely there was the people more than 90% to infect chickenpox in 15 years old.And the dangerous group of complication be less than 5 years old, greater than 20 years old person and immunological incompetence person.To generate heat and whole body property red grouper pimple, herpes, crust rash to occur in batch as feature.Winter and spring is multiple, and its infectivity is strong, and contact or the spittle all can infect.The susceptible sickness rate can reach more than 95%, and preschooler is common.Clinically maculopapule, vesicle and incrustation occur with mucocutaneous, and each phase erythra exists for characteristics simultaneously in batches.
Chickenpox belongs to viral infectious, and herpes zoster belongs to the same viral infection.Some people, in addition some doctors because the childhood period suffer from the chickenpox favourable prognosis, so usually despised the harm of chickenpox.In fact, the child suffer from after the chickenpox might the secondary varicella encephalitis, the serious complication such as constitutional varicella pneumonia.In addition, staphylococcus, streptococcus also can infect through erythra, cause furuncle, carbuncle, Pyoderma, erysipelas or cellulitis etc., even cause septicemia, pneumonia, suppurative arthritis or osteomyelitis.The anemia of pregnant woman infected chickenpox in conceived 3-4 month, the baby that gives birth to may suffer from congenital chickenpox syndrome in the future.When the anemia of pregnant woman suffered from chickenpox before childbirth, its baby that gives birth to can not get the maternal antibody protection, in 5-10 days serious chickenpox can occur after the birth.After some children's suffered from chickenpox, virus can be hidden in craniospinal ganglia for a long time, was unlikelyly removed by Serum Antibody.After growing up, perhaps when immune status changed, virus was active once again, and causes herpes zoster.The chickenpox prognosis is generally good.Crust comes off rear most without cicatrix, but gos deep into cortex and secondary infection person is arranged at varioliform exanthema, can leave shallow cicatrix, usually appears at forehead and face, ovalize.Serious symptom chickenpox or concurrent heavy encephalitis, pneumonia person can cause death.Accept immunosuppressant or the cell toxicity medicament therapist generation chickenpox state of an illness is heavier, case fatality rate is high.
At present, the Chinese patent medicine that is used for the treatment of chickenpox all in various degree exist slow, the defective such as curative effect is remarkable not that takes effect, have much room for improvement.
Summary of the invention
That technical problem to be solved by this invention is that overcome existing treatment chickenpox existing takes effect is slow, curative effect not significantly, the defective such as toxic and side effects is large, the Chinese medicine composition of the treatment chickenpox that provide a kind of instant effect, determined curative effect, has no side effect;
Another technical problem to be solved by this invention provides a kind of method for preparing above-mentioned Chinese medicine composition.
Above-mentioned technical problem to be solved by this invention is achieved through the following technical solutions:
A kind of Chinese medicine composition for the treatment of chickenpox comprises that each component of following weight portion forms:
Cortex Lycii 15-35 part, Cortex Mori 15-35 part, Cortex Moutan 15-35 part, Folium Isatidis 12-30 part, Radix Scutellariae 12-30 part, Radix Isatidis 10-25 part, Fructus Forsythiae 5-12 part, Radix Scrophulariae 5-12 part, Rhizoma Anemarrhenae 5-12 part, Fructus Arctii 5-12 part, Radix Rehmanniae 4-10 part, Semen Plantaginis 4-10 part, Fructus Gardeniae 2-9 part, Radix Glycyrrhizae 1-6 part;
Preferably, the weight portion of each component is: Cortex Lycii 20-35 part, Cortex Mori 20-35 part, Cortex Moutan 15-30 part, Folium Isatidis 12-25 part, Radix Scutellariae 12-25 part, Radix Isatidis 10-20 part, Fructus Forsythiae 5-10 part, Radix Scrophulariae 5-10 part, Rhizoma Anemarrhenae 5-10 part, Fructus Arctii 5-10 part, Radix Rehmanniae 4-8 part, Semen Plantaginis 4-8 part, Fructus Gardeniae 2-6 part, Radix Glycyrrhizae 1-5 part;
Preferred, the weight portion of each component is: 30 parts of Cortex Lycii, 30 parts of Cortex Mori, 25 parts of Cortex Moutans, 20 parts of Folium Isatidiss, 20 parts of Radix Scutellariaes, 15 parts of Radix Isatidis, 8 parts of Fructus Forsythiaes, 8 parts of Radix Scrophulariaes, 8 parts of the Rhizoma Anemarrhenaes, 8 parts of Fructus Arctiis, 6 parts in the Radix Rehmanniae, 6 parts of Semen Plantaginiss, 4 parts of Fructus Gardeniaes, 3 parts in Radix Glycyrrhizae.
Chinese medicine composition of the present invention is based on the inventor to the pathogenetic research of the deep layer of chickenpox and Therapeutic Principle thereof, simultaneously according to inventor for many years clinical experience and pharmaceutical research achievement, filter out that heat-clearing and toxic substances removing, removing heat from blood are moisturized, tonifying YIN promotes the production of body fluid, the crude drug of lung heat clearing pathogenic fire reducing, form according to certain weight proportion prescription.
Cortex Lycii: be the root bark of matrimony vine of solanaceae plant Lycium chinense Mill..Nature and flavor: cold in nature, sweet in the mouth.Function cures mainly: removing heat from blood is except steaming the lung heat clearing pathogenic fire reducing.Be used for deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis.
Cortex Mori: be the root bark of moraceae plants Mulberry Morus alba L..Main product in Anhui, the ground such as Henan, Zhejiang, Jiangsu, Hunan.Effect: eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema.Be used for the lung-heat cough with asthma, the edema of the face, the diseases such as dysuria.
Cortex Moutan: be the dry root bark of ranunculaceae peony.Clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The calentura later stage, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and pounce on the pain of injury; The rheumatism pyretic arthralgia.
Folium Isatidis: the dried leaves of cruciferae isatis Isatis indigotica Fort..Heat clearing away, detoxifcation, removing heat from blood, hemostasis.Control epidemic febrile disease intenseness of heat excessive thirst, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas is spitted blood epistaxis, jaundice, dysentery, sore throat, aphtha, swollen ulcer drug.
Radix Scrophulariae: the dry root of goatweed Radix Scrophulariae Scrophularia ningpoensis Hemsl..Cure mainly: epidemic febrile disease and nutrient blood, fever of the body, excessive thirst, crimson tongue, send out speckle, hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency not awake, Tianjin hinder constipation, order puckery dim-sighted, the throat larynx swells and ache, scrofula sucutaneous nodule, skin sore.
Fructus Arctii: be Compositae biennial herb plant Fructus Arctii (formal name used at school: dry mature fruit Arctium lappa L.).Have another name called Fructus Arctii, FRUCTUS ARCTII, evil reality etc.Has dispelling wind and heat pathogens, lung qi dispersing rash, sore-throat relieving eliminating stagnation, the effect of removing toxic substances and promoting subsidence of swelling.Belong to wind-heat-dispersing medicinal in the diaphoretic medicine.
The Radix Rehmanniae: the Radix Rehmanniae also is Radix Rehmanniae, the fresh or dry tuber of Scrophulariaceae herbaceos perennial Radix Rehmanniae Rehmannia glutinosa Libosch..The effect that Radix Rehmanniae has clearing away heat and cooling blood, tonifying YIN to promote the production of body fluid.
Semen Plantaginis: Plantago asiatica L.Plantago major L.Plantago depressa Willd. Herba Plantaginis has another name called the wheel dish, and perennial herb connects scape up to 50 centimetres, the tool fibrous root.Nature and flavor: sweet; Light; Cold nature.Return lung meridian; Liver Channel; Kidney channel; Urinary bladder channel.Function: clearing away heat and promoting diuresis; Eliminating dampness by diuresis antidiarrheal; Make eye bright; Eliminate the phlegm.Cure mainly: main dysuria; The stranguria with turbid discharge leukorrhagia; The edema distension; The heat-damp in summer dysentery; Conjunctival congestion is hidden from view; The expectorant heat syndrome cough is breathed heavily.Have eliminate the phlegm, antitussive, the effect such as relieving asthma.
Radix Glycyrrhizae: property is sweet, and is flat.GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
The effect that has better heat clearing and damp drying when in above-mentioned Chinese medicine composition, adding the raw material of following weight portion: Cortex Fraxini 5-12 part, Radix Sophorae Flavescentis 5-12 part, Gypsum Fibrosum 4-10 part, Cortex Phellodendri 4-10 part, Radix Gentianae 4-10 part, Rhizoma Atractylodis 4-10 part, Herba Erodii 4-10 part; Preferably, the weight portion of each raw material is: 10 parts of Cortex Fraxinis, 10 parts of Radix Sophorae Flavescentiss, 6 parts in Gypsum Fibrosum, 8 parts of Cortex Phellodendris, 8 parts of Radix Gentianaes, 8 parts of Rhizoma Atractylodis, 8 parts of Herba Erodiis.
Cortex Fraxini: be dry branch skin or the dried bark of Oleaceae plants fraxinus rhynchophylla Hance, Chinese ash, sharp leaf Chinese ash or place post Chinese ash.Nature and flavor are bitter, and are cold.Heat clearing and damp drying Chinese medicine.Cure mainly: heat clearing and damp drying, liver heat removing and eyesight improving, antiasthmatic-antitussive.Be used for pyretic toxicity dysentery, conjunctival congestion and swelling pain, the living cataracta of order.
Herba Erodii: English name: HERBA ERODII/HERBA GERANII.Another name: old stork mouth, crow mouth, pass through muscle, always pass through muscle, old tendon Bovis seu Bubali.The source: (or the dry drying of the band fruit herb of Carolina Cranesbill Herb Geranium carolinianum L. is used as medicine for the plant Mang cattle Seedling Erodium stephanianum Willd. of Mang cattle Seedling section, Herba Erodii Geranium Wilfordii Maxim., nepal cranesbill, Siberia Herba Erodii, tuber Herba Erodii and mutation high mountain tuber Herba Erodii thereof.Have wind-damp dispelling, the meridian dredging, antidiarrheal is sharp.Be used for rheumatic arthralgia, numbness contracture, muscles and bones is ached, the effect of dysentery.
Radix Gentianae: be root and the rhizome of gentianaceae plant Radix Gentianae, bar leaf Radix Gentianae, three flower Radix Gentianae and Yunnan Radix Gentianae.Effect with heat clearing away, eliminating pathogen in the liver, arresting convulsion.The Compendium of Material Medica record: " nature and flavor are bitter, and are puckery, Great Cold, nontoxic.Cure mainly cold and heat between bone, frightened pathogenic factor gas, continue and hinder absolutely, decide the five internal organs, the parasite killing poison.”
Has the effect of better heat-clearing and toxic substances removing when further adding in the present invention the raw material of following weight portion in the drug composition: Herba Violae 5-12 part, Herba Taraxaci 5-12 part, Herba Houttuyniae 3-8 part, Flos Lonicerae 4-10 part, Herba Saxifragae 4-10 part; Preferably, the weight portion of each raw material is: 9 parts of Herba Violaes, 9 parts of Herba Taraxacis, 6 parts of Herba Houttuyniae, 7 parts of Flos Loniceraes, 7 parts of Herba Saxifragaes.
Herba Violae: the dry herb of Violaceae Chinese violet Viola yedonensis Makino.Meridian distribution of property and flavor: bitter, hot, cold, nontoxic; GUIXIN, Liver Channel.Function cures mainly: can be used as medicine its mildly bitter flavor cold in nature, heat-clearing and toxic substances removing, removing heat from blood detumescence.Cure mainly jaundice, dysentery, mastitis, conjunctival congestion and swelling pain, pharyngitis; Traumatic injury, carbuncle, venom etc. are controlled in external application.
Herba Taraxaci: property is sweet, and little hardship is cold.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Sweet cold removing summer-heat, bitter with using pungent drugs for dispersion and bitter drugs for purgation, the special removing toxic substances and promoting subsidence of swelling of merit is for controlling the acute mastitis key medicine.Have the merit of dampness removing concurrently.
Flos Lonicerae: property is sweet, little hardship, and suffering, cold.Return lung, stomach, the heart, large intestine channel.Has dispelling wind-heat, the effect of removing summer-heat blood poison.
Herba Saxifragae (formal name used at school: be saxifragaceae plant Saxifraga stolonifera Curt.).Contain alkaloid, potassium nitrate, potassium chloride, Folium Vaccinii vitis-idaeae phenolic glycoside (arbutin), phenolase contained in its chloroplast can be with the cis caffeic acid; Little hardship, suffering, cold, slightly poisonous; Effect with expelling wind and clearing away heat, removing pathogenic heat from blood and toxic substance from the body.
Has the effect of better heat clearing away clearing away heat and cooling blood when further adding in the present invention the raw material of following weight portion in the drug composition: Herba Scutellariae Barbatae 5-12 part, Rhizoma et Radix Thalictri 5-12 part, Herba Andrographis 5-12 part, Herba Lophatheri 2-8 part, Rhizoma Imperatae 2-8 part; Preferably, the weight portion of each crude drug is: 10 parts of Herba Scutellariae Barbataes, 10 parts of Rhizoma et Radix Thalictri, 9 parts of Herba Andrographis, 6 parts of Herba Lophatheris, 6 parts of Rhizoma Imperataes.
The heat-clearing and toxic substances removing that each medicine compatibility is played together altogether among the side of the present invention, the removing heat from blood detumescence, the effect of lung heat clearing pathogenic fire reducing, Chinese medicine composition of the present invention is for the chickenpox treating both the principal and secondary aspects of a disease, and clinical observation on the therapeutic effect confirms that Chinese medicine composition of the present invention is reliable, true for the chickenpox determined curative effect.Chinese medicine composition of the present invention is nontoxic, and is safe and reliable, has no adverse reaction after taking, clinical use safety.
The crude drug of respectively distinguishing the flavor of that the present invention is used can be bought at pharmacy and obtain.
Medicine activity component of the present invention can add various adjuvants required when preparing different dosage form, such as disintegrating agent, lubricant, adhesive etc., method of Chinese medicinal with routine is prepared into any suitable clinical preparation, such as oral formulations or external preparation, described oral formulations can be pill, powder, granule, capsule, tablet, oral liquid, drop pill etc.; Used external preparation can unguentum, washing liquid, liniment etc.
A kind of preparation method of Chinese medicine composition of the present invention: after each crude drug of the present invention taken by weighing by described weight portion proportioning, pulverize, sieve (for example can be the 600-1000 mesh sieve), and get final product.Certainly, after also each crude drug can being pulverized, add required adjuvant or the excipient of preparations shaping, be prepared into capsule, tablet or pill according to conventional method.
The another kind of preparation method of Chinese medicine composition of the present invention: take by weighing each crude drug by described weight portion; Each crude drug water is decocted, merge decoction liquor, filter, filtrate is condensed into clear paste, adds adjuvant or the excipient of preparations shaping, preparations shaping, and get final product.
The usage of Chinese medicine composition of the present invention and consumption: dosage of the present invention depends on the factors such as concrete dosage form, patient's age, health status.As guidance: usage and dosage: capsule, each capsule content 0.6 gram crude drug, each oral 1 to 3, three times on the one, 7 days is a course for the treatment of.
The specific embodiment
Further describe the present invention below in conjunction with specific embodiment; these embodiment only are exemplary; what those skilled in the art should understand that is; can make amendment or replace the details of technical solution of the present invention and form lower without departing from the spirit and scope of the present invention, but these modifications and replacing all fall within the scope of protection of the present invention.
The preparation of embodiment 1 capsule
Take by weighing each crude drug (unit: g): Cortex Lycii 15, Cortex Mori 15, Cortex Moutan 15, Folium Isatidis 12, Radix Scutellariae 12, Radix Isatidis 10, Fructus Forsythiae 5, Radix Scrophulariae 5, the Rhizoma Anemarrhenae 5, Fructus Arctii 5, the Radix Rehmanniae 4, Semen Plantaginis 4, Fructus Gardeniae 2, Radix Glycyrrhizae 1 by following weight; Above-mentioned each crude drug is decocted with water secondary, add 4 times of weight of water for the first time, decocted 2 hours, add 5 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.17-1.19 (60 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 2 capsules
Take by weighing each crude drug (unit: g): Cortex Lycii 35, Cortex Mori 35, Cortex Moutan 35, Folium Isatidis 30, Radix Scutellariae 30, Radix Isatidis 25, Fructus Forsythiae 12, Radix Scrophulariae 12, the Rhizoma Anemarrhenae 12, Fructus Arctii 12, the Radix Rehmanniae 10, Semen Plantaginis 10, Fructus Gardeniae 9, Radix Glycyrrhizae 6 by following weight; Above-mentioned each crude drug is decocted with water secondary, add 6 times of weight of water for the first time, decocted 2 hours, add 4 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.17-1.19 (60 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 3 capsules
Take by weighing each crude drug (unit: g): Cortex Lycii 20, Cortex Mori 20, Cortex Moutan 15, Folium Isatidis 12, Radix Scutellariae 12, Radix Isatidis 10, Fructus Forsythiae 5, Radix Scrophulariae 5, the Rhizoma Anemarrhenae 5, Fructus Arctii 5, the Radix Rehmanniae 4, Semen Plantaginis 4, Fructus Gardeniae 2, Radix Glycyrrhizae 1 by following weight; Above-mentioned each crude drug is decocted with water secondary, add 4 times of weight of water for the first time, decocted 2 hours, add 5 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.30-1.35 (55 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 4 capsules
Take by weighing each crude drug (unit: g): Cortex Lycii 35, Cortex Mori 35, Cortex Moutan 30, Folium Isatidis 25, Radix Scutellariae 25, Radix Isatidis 20, Fructus Forsythiae 10, Radix Scrophulariae 10, the Rhizoma Anemarrhenae 10, Fructus Arctii 10, the Radix Rehmanniae 8, Semen Plantaginis 8, Fructus Gardeniae 6, Radix Glycyrrhizae 5 by following weight; Above-mentioned each crude drug is decocted with water secondary, add 4 times of weight of water for the first time, decocted 2 hours, add 5 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.30-1.35 (55 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 5 capsules
Take by weighing each crude drug (unit: g): Cortex Lycii 30, Cortex Mori 30, Cortex Moutan 25, Folium Isatidis 20, Radix Scutellariae 20, Radix Isatidis 15, Fructus Forsythiae 8, Radix Scrophulariae 8, the Rhizoma Anemarrhenae 8, Fructus Arctii 8, the Radix Rehmanniae 6, Semen Plantaginis 6, Fructus Gardeniae 4, Radix Glycyrrhizae 3 by following weight; Above-mentioned each crude drug is decocted with water secondary, add 6 times of weight of water for the first time, decocted 2 hours, add 4 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.17-1.19 (60 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 6 capsules
Take by weighing each crude drug (unit: g): Cortex Lycii 30, Cortex Mori 30, Cortex Moutan 25, Folium Isatidis 20, Radix Scutellariae 20, Radix Isatidis 15, Fructus Forsythiae 8, Radix Scrophulariae 8, the Rhizoma Anemarrhenae 8, Fructus Arctii 8, the Radix Rehmanniae 6, Semen Plantaginis 6, Fructus Gardeniae 4, Radix Glycyrrhizae 3, Cortex Fraxini 10, Radix Sophorae Flavescentis 10, Gypsum Fibrosum 6, Cortex Phellodendri 8, Radix Gentianae 8, Rhizoma Atractylodis 8, Herba Erodii 8 by following weight; Above-mentioned each crude drug is decocted with water secondary, add 6 times of weight of water for the first time, decocted 2 hours, add 4 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.17-1.19 (60 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 7 capsules
Take by weighing each crude drug (unit: g): Cortex Lycii 30, Cortex Mori 30, Cortex Moutan 25, Folium Isatidis 20, Radix Scutellariae 20, Radix Isatidis 15, Fructus Forsythiae 8, Radix Scrophulariae 8, the Rhizoma Anemarrhenae 8, Fructus Arctii 8, the Radix Rehmanniae 6, Semen Plantaginis 6, Fructus Gardeniae 4, Radix Glycyrrhizae 3, Herba Violae 9, Herba Taraxaci 9, Herba Houttuyniae 6, Flos Lonicerae 7, Herba Saxifragae 7 by following weight; Above-mentioned each crude drug is decocted with water secondary, add 6 times of weight of water for the first time, decocted 2 hours, add 4 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.17-1.19 (60 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The preparation of embodiment 8 capsules
Take by weighing each crude drug (unit: g): Cortex Lycii 30, Cortex Mori 30, Cortex Moutan 25, Folium Isatidis 20, Radix Scutellariae 20, Radix Isatidis 15, Fructus Forsythiae 8, Radix Scrophulariae 8, the Rhizoma Anemarrhenae 8, Fructus Arctii 8, the Radix Rehmanniae 6, Semen Plantaginis 6, Fructus Gardeniae 4, Radix Glycyrrhizae 3, Herba Scutellariae Barbatae 10, Rhizoma et Radix Thalictri 10, Herba Andrographis 9, Herba Lophatheri 6, Rhizoma Imperatae 6 by following weight; Above-mentioned each crude drug is decocted with water secondary, add 6 times of weight of water for the first time, decocted 2 hours, add 4 times of weight of water for the second time, decocted 1.5 hours; Decoction liquor is merged, filter, filtrate is concentrated into the clear paste that relative density is 1.17-1.19 (60 ℃); Merge clear paste twice, add appropriate amount of starch, mixing, dry, pulverize, add the appropriate amount of ethanol granulation, drying, granulate, filled capsules, and get final product.
The clinical observation on the therapeutic effect test of test example 1 traditional Chinese medicine composition for treating chickenpox of the present invention
One, physical data: 152 routine patients all meet the seborrheic dermatitis diagnostic criteria, wherein, and male 98 examples, women 86 examples, 6 months～15 years old age, average 5 years old.The patient is divided into four groups at random, every group of 38 examples; Four groups of no significant differences on sex, age, the course of disease and coincident with severity degree of condition.
Two, trial drug
The medicine that embodiment of the invention 1-8 is prepared.
Three, Therapeutic Method
152 routine patients are divided into 4 groups at random, that is: test 1 group, 2 groups of tests, test 3 groups and test 4 groups, every group of each 38 example are tested 1 group and are adopted the prepared capsule treatment of embodiment 1-5, test 2 groups and adopt the prepared capsules treatment of embodiment 6; Test 3 groups and adopt embodiment 7 prepared capsules to treat, test 4 groups and adopt embodiment 8 prepared capsules to treat; Oral, one time 3 (0.6g crude drug/grain), 3 times on the one, 7 days is a course for the treatment of, treats altogether 2 courses for the treatment of; Period in a medicine is withdrawn other related drugs and other treatment.
Four, efficacy assessment standard
Efficacy assessment standard and foundation: criterion of therapeutical effect: treat forward and backward 1 week, 2 weeks, 3 weeks, patient's sings and symptoms is carried out objective scoring.Clinical symptoms and sign are undertaken by 4 grades of point systems, 0=without, 1=is slight, 2=moderate, 3=severe.Recovery from illness reduces＞95% for integrated value, and produce effects is integrated value＞60%, transfers well integrated value minimizing 20%～60% to, and invalid is that integrated value reduces＜20%.Integrated value: total mark * 100% before (integration after integration before the treatment-treatment)/treatment.
Five, clinical observation result
Clinical observation result sees Table 1.
The clinical observation on the therapeutic effect result of the test of table 1 traditional Chinese medicine composition for treating chickenpox of the present invention
Clinical observation on the therapeutic effect is the result show, Chinese medicine composition of the present invention has significant curative effect for patient with varicella; Safety observe to be found, does not observe any clinical adverse, show Chinese medicine composition clinical practice of the present invention safely, have no side effect.
Claims (10)
1. a Chinese medicine composition for the treatment of chickenpox comprises that each component of following weight portion forms: Cortex Lycii 15-35 part, Cortex Mori 15-35 part, Cortex Moutan 15-35 part, Folium Isatidis 12-30 part, Radix Scutellariae 12-30 part, Radix Isatidis 10-25 part, Fructus Forsythiae 5-12 part, Radix Scrophulariae 5-12 part, Rhizoma Anemarrhenae 5-12 part, Fructus Arctii 5-12 part, Radix Rehmanniae 4-10 part, Semen Plantaginis 4-10 part, Fructus Gardeniae 2-9 part and Radix Glycyrrhizae 1-6 part.
2. according to Chinese medicine composition claimed in claim 1, it is characterized in that the weight portion of each component is: Cortex Lycii 20-35 part, Cortex Mori 20-35 part, Cortex Moutan 15-30 part, Folium Isatidis 12-25 part, Radix Scutellariae 12-25 part, Radix Isatidis 10-20 part, Fructus Forsythiae 5-10 part, Radix Scrophulariae 5-10 part, Rhizoma Anemarrhenae 5-10 part, Fructus Arctii 5-10 part, Radix Rehmanniae 4-8 part, Semen Plantaginis 4-8 part, Fructus Gardeniae 2-6 part, Radix Glycyrrhizae 1-5 part; Preferably, the weight portion of each component is: 30 parts of Cortex Lycii, 30 parts of Cortex Mori, 25 parts of Cortex Moutans, 20 parts of Folium Isatidiss, 20 parts of Radix Scutellariaes, 15 parts of Radix Isatidis, 8 parts of Fructus Forsythiaes, 8 parts of Radix Scrophulariaes, 8 parts of the Rhizoma Anemarrhenaes, 8 parts of Fructus Arctiis, 6 parts in the Radix Rehmanniae, 6 parts of Semen Plantaginiss, 4 parts of Fructus Gardeniaes, 3 parts in Radix Glycyrrhizae.
3. a Chinese medicine composition for the treatment of chickenpox comprises that each component of following weight portion forms: Cortex Lycii 15-35 part, Cortex Mori 15-35 part, Cortex Moutan 15-35 part, Folium Isatidis 12-30 part, Radix Scutellariae 12-30 part, Radix Isatidis 10-25 part, Fructus Forsythiae 5-12 part, Radix Scrophulariae 5-12 part, Rhizoma Anemarrhenae 5-12 part, Fructus Arctii 5-12 part, Radix Rehmanniae 4-10 part, Semen Plantaginis 4-10 part, Fructus Gardeniae 2-9 part, Radix Glycyrrhizae 1-6 part, Cortex Fraxini 5-12 part, Radix Sophorae Flavescentis 5-12 part, Gypsum Fibrosum 4-10 part, Cortex Phellodendri 4-10 part, Radix Gentianae 4-10 part, Rhizoma Atractylodis 4-10 part, Herba Erodii 4-10 part.
4. according to Chinese medicine composition claimed in claim 1, it is characterized in that the weight portion of each component is: 30 parts of Cortex Lycii, 30 parts of Cortex Mori, 25 parts of Cortex Moutans, 20 parts of Folium Isatidiss, 20 parts of Radix Scutellariaes, 15 parts of Radix Isatidis, 8 parts of Fructus Forsythiaes, 8 parts of Radix Scrophulariaes, 8 parts of the Rhizoma Anemarrhenaes, 8 parts of Fructus Arctiis, 6 parts in the Radix Rehmanniae, 6 parts of Semen Plantaginiss, 4 parts of Fructus Gardeniaes, 3 parts in Radix Glycyrrhizae, 10 parts of Cortex Fraxinis, 10 parts of Radix Sophorae Flavescentiss, 6 parts in Gypsum Fibrosum, 8 parts of Cortex Phellodendris, 8 parts of Radix Gentianaes, 8 parts of Rhizoma Atractylodis, 8 parts of Herba Erodiis.
5. a Chinese medicine composition for the treatment of chickenpox comprises that each component of following weight portion forms: Cortex Lycii 15-35 part, Cortex Mori 15-35 part, Cortex Moutan 15-35 part, Folium Isatidis 12-30 part, Radix Scutellariae 12-30 part, Radix Isatidis 10-25 part, Fructus Forsythiae 5-12 part, Radix Scrophulariae 5-12 part, Rhizoma Anemarrhenae 5-12 part, Fructus Arctii 5-12 part, Radix Rehmanniae 4-10 part, Semen Plantaginis 4-10 part, Fructus Gardeniae 2-9 part, Radix Glycyrrhizae 1-6 part, Herba Violae 5-12 part, Herba Taraxaci 5-12 part, Herba Houttuyniae 3-8 part, Flos Lonicerae 4-10 part, Herba Saxifragae 4-10 part.
6. according to Chinese medicine composition claimed in claim 1, it is characterized in that the weight portion of each component is: 30 parts of Cortex Lycii, 30 parts of Cortex Mori, 25 parts of Cortex Moutans, 20 parts of Folium Isatidiss, 20 parts of Radix Scutellariaes, 15 parts of Radix Isatidis, 8 parts of Fructus Forsythiaes, 8 parts of Radix Scrophulariaes, 8 parts of the Rhizoma Anemarrhenaes, 8 parts of Fructus Arctiis, 6 parts in the Radix Rehmanniae, 6 parts of Semen Plantaginiss, 4 parts of Fructus Gardeniaes, 3 parts in Radix Glycyrrhizae, 9 parts of Herba Violaes, 9 parts of Herba Taraxacis, 6 parts of Herba Houttuyniae, 7 parts of Flos Loniceraes, 7 parts of Herba Saxifragaes.
7. a Chinese medicine composition for the treatment of chickenpox comprises that each component of following weight portion forms: Cortex Lycii 15-35 part, Cortex Mori 15-35 part, Cortex Moutan 15-35 part, Folium Isatidis 12-30 part, Radix Scutellariae 12-30 part, Radix Isatidis 10-25 part, Fructus Forsythiae 5-12 part, Radix Scrophulariae 5-12 part, Rhizoma Anemarrhenae 5-12 part, Fructus Arctii 5-12 part, Radix Rehmanniae 4-10 part, Semen Plantaginis 4-10 part, Fructus Gardeniae 2-9 part, Radix Glycyrrhizae 1-6 part, Herba Scutellariae Barbatae 5-12 part, Rhizoma et Radix Thalictri 5-12 part, Herba Andrographis 5-12 part, Herba Lophatheri 2-8 part, Rhizoma Imperatae 2-8 part.
8. according to Chinese medicine composition claimed in claim 1, it is characterized in that the weight portion of each component is: 30 parts of Cortex Lycii, 30 parts of Cortex Mori, 25 parts of Cortex Moutans, 20 parts of Folium Isatidiss, 20 parts of Radix Scutellariaes, 15 parts of Radix Isatidis, 8 parts of Fructus Forsythiaes, 8 parts of Radix Scrophulariaes, 8 parts of the Rhizoma Anemarrhenaes, 8 parts of Fructus Arctiis, 6 parts in the Radix Rehmanniae, 6 parts of Semen Plantaginiss, 4 parts of Fructus Gardeniaes, 3 parts in Radix Glycyrrhizae, 10 parts of Herba Scutellariae Barbataes, 10 parts of Rhizoma et Radix Thalictri, 9 parts of Herba Andrographis, 6 parts of Herba Lophatheris, 6 parts of Rhizoma Imperataes.
9. method for preparing any one described Chinese medicine composition of claim 1-8 may further comprise the steps:
(1), takes by weighing each crude drug by described weight proportion;
(2) each crude drug water is decocted, merge decoction liquor, filter, filtrate is condensed into clear paste, adds adjuvant or the excipient of preparations shaping, preparations shaping, and get final product.
10. any one described Chinese medicine composition of claim 1-8 is preparing the purposes for the treatment of in the chickenpox medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012104671148A CN102973770A (en) | 2012-11-13 | 2012-11-13 | Varicella-curing Chinese medicine combination and preparing method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012104671148A CN102973770A (en) | 2012-11-13 | 2012-11-13 | Varicella-curing Chinese medicine combination and preparing method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102973770A true CN102973770A (en) | 2013-03-20 |
Family
ID=47848305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012104671148A Pending CN102973770A (en) | 2012-11-13 | 2012-11-13 | Varicella-curing Chinese medicine combination and preparing method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102973770A (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103800524A (en) * | 2014-01-19 | 2014-05-21 | 逯玲 | Traditional Chinese medicine mixture for treating excessive noxious heat type chicken pox |
| CN103908560A (en) * | 2014-04-04 | 2014-07-09 | 青岛大学医学院附属医院 | Traditional Chinese medicine preparation for treating chicken pox |
| CN104257840A (en) * | 2014-09-29 | 2015-01-07 | 淄博市食品药品检验所 | Pharmaceutical composition for treating eczema of infants and young children and preparation method of pharmaceutical composition |
| CN105169123A (en) * | 2015-07-02 | 2015-12-23 | 王翠霞 | Chinese medicinal powder for treatment of infantile toxic heat flourishing chickenpox and preparation method thereof |
| CN105434971A (en) * | 2016-01-20 | 2016-03-30 | 赵世明 | Traditional Chinese medicine composition for treating chicken pox |
| CN105560961A (en) * | 2015-09-18 | 2016-05-11 | 范月辉 | Traditional Chinese medicine formula for treating Kaposi's varicelliform eruption |
| CN105833073A (en) * | 2016-04-28 | 2016-08-10 | 苏州市天灵中药饮片有限公司 | Chinese herb preparation capable of clearing away heat and toxic materials and application thereof |
| CN109663020A (en) * | 2019-02-25 | 2019-04-23 | 广西中医药大学 | A kind of Yao medicinal composition that treating pruritus and its application |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101954012A (en) * | 2010-10-18 | 2011-01-26 | 李玉娥 | Traditional Chinese medicine for treating chicken pox |
-
2012
- 2012-11-13 CN CN2012104671148A patent/CN102973770A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101954012A (en) * | 2010-10-18 | 2011-01-26 | 李玉娥 | Traditional Chinese medicine for treating chicken pox |
Non-Patent Citations (2)
| Title |
|---|
| 李春生: "中西医结合治疗成人水痘36例", 《陕西中医》, vol. 24, no. 9, 31 December 2003 (2003-12-31), pages 791 - 792 * |
| 汪受传等: "水痘中医诊疗指南", 《中医儿科杂志》, vol. 7, no. 3, 31 May 2011 (2011-05-31), pages 1 - 4 * |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103800524A (en) * | 2014-01-19 | 2014-05-21 | 逯玲 | Traditional Chinese medicine mixture for treating excessive noxious heat type chicken pox |
| CN103908560A (en) * | 2014-04-04 | 2014-07-09 | 青岛大学医学院附属医院 | Traditional Chinese medicine preparation for treating chicken pox |
| CN104257840A (en) * | 2014-09-29 | 2015-01-07 | 淄博市食品药品检验所 | Pharmaceutical composition for treating eczema of infants and young children and preparation method of pharmaceutical composition |
| CN104257840B (en) * | 2014-09-29 | 2017-01-11 | 淄博市食品药品检验研究院 | Pharmaceutical composition for treating eczema of infants and young children and preparation method of pharmaceutical composition |
| CN105169123A (en) * | 2015-07-02 | 2015-12-23 | 王翠霞 | Chinese medicinal powder for treatment of infantile toxic heat flourishing chickenpox and preparation method thereof |
| CN105169123B (en) * | 2015-07-02 | 2018-12-14 | 王翠霞 | A kind of traditional Chinese medicine powder and preparation method thereof for treating children's extreme noxious heat varicella |
| CN105560961A (en) * | 2015-09-18 | 2016-05-11 | 范月辉 | Traditional Chinese medicine formula for treating Kaposi's varicelliform eruption |
| CN105434971A (en) * | 2016-01-20 | 2016-03-30 | 赵世明 | Traditional Chinese medicine composition for treating chicken pox |
| CN105833073A (en) * | 2016-04-28 | 2016-08-10 | 苏州市天灵中药饮片有限公司 | Chinese herb preparation capable of clearing away heat and toxic materials and application thereof |
| CN109663020A (en) * | 2019-02-25 | 2019-04-23 | 广西中医药大学 | A kind of Yao medicinal composition that treating pruritus and its application |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102973770A (en) | Varicella-curing Chinese medicine combination and preparing method thereof | |
| CN102973779B (en) | Traditional Chinese medicine composition for treating seborrheic dermatitis and acne and preparation method thereof | |
| CN102488792A (en) | Traditional Chinese medicinal composition for treating rhinitis and paranasal sinusitis and preparation method thereof | |
| CN102000175A (en) | Traditional Chinese medicine composition for treating hemorrhoids and preparation method thereof | |
| CN104758773A (en) | Traditional Chinese medicine preparation for treating hand-foot-and-mouth disease | |
| CN103599403B (en) | Traditional Chinese medicine composition for treating migraine and preparation method thereof | |
| CN103169883B (en) | Traditional Chinese medicine for treating infantile jaundice | |
| CN104958448A (en) | Medicine for treating puerperal infection | |
| CN103432466B (en) | Female pelvic inflammatory disease treatment traditional Chinese medicine composition and preparation method thereof | |
| CN102988692B (en) | Traditional Chinese medicine composition for treating herpes zoster and preparation method thereof | |
| CN102488758A (en) | Traditional Chinese medicine composition for treating allergic rhinitis and preparation method thereof | |
| CN106177542A (en) | The Chinese prescription of a kind of summer heat clearing toxin resolving and goods thereof | |
| CN105521332A (en) | Traditional Chinese medicinal composition for treating anal fissure, and preparation method and application thereof | |
| CN105535730A (en) | Novel traditional Chinese medicine composition for treating coughs and preparation method thereof | |
| CN105327182A (en) | Medicine for treating child pertussis and preparation method thereof | |
| CN104771585A (en) | Traditional Chinese medicine composition for treating acute nephritis and preparation method thereof | |
| CN104606600A (en) | Traditional Chinese medicine composition for treating interstitial lung disease and preparation method of composition | |
| CN104399036A (en) | Medicine composition for treating chronic diarrhea and application of medicine composition | |
| CN102861227B (en) | Traditional Chinese medicine composition for treating suppurative meningitis sequelae and preparation method of traditional Chinese medicine composition | |
| CN105395914A (en) | Traditional Chinese medicine composition for treating cystolith and preparation method and application thereof | |
| CN105434874A (en) | Medicine for treating epifolliculitis and preparation method of medicine | |
| CN105343556A (en) | Medicine for treating thromboangiitis obliterans and preparation method thereof | |
| CN104162077A (en) | Traditional Chinese medicine for treating infantile eczema | |
| CN105381410A (en) | Traditional Chinese medicinal preparation for treating hepatitis | |
| CN103655846B (en) | Traditional Chinese medicine for treating gastric collateral stasis syndrome type gastroptosis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20130320 |