CN102861227B - Traditional Chinese medicine composition for treating suppurative meningitis sequelae and preparation method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for treating suppurative meningitis sequelae and preparation method of traditional Chinese medicine composition Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating suppurative meningitis sequelae and a preparation method of the traditional Chinese medicine composition. According to the traditional Chinese medicine composition, 6-18 parts of unprocessed rehmannia roots, 5-15 parts of red peony roots, 5-15 parts of white peony roots, 6-18 parts of dwarf lilyturf tuber, 3-8 parts of radix glycyrrhizae preparata, 5-15 parts of Chinese angelica, 15-45 parts of milkvetch roots, 5-15 parts of earthworms, 5-15 parts of red-rooted salvia roots, 5-15 parts of fructus chaenomelis lagenariae, 5-15 parts ofloofah sponges, 6-18 parts of mulberry twigs, 5-15 parts of common anemarrhena rhizome, 6-18 parts of Chinese taxillus herbs and 3-8 parts of fried scorpions are used as raw materials, and the raw materials are processed by methods of smashing, concentrating, extracting, drying and then smashing respectively according to different characteristics of each part of traditional Chinese medicines, then proportionally prepared and finally combined with carriers or excipients which are acceptable in pharmacy to be prepared into pills, tablets, capsules, powders and the like. According to the traditional Chinese medicine composition for treating the suppurative meningitis sequelae, actual cure rates of the suppurative meningitis sequelae can be improved, the traditional Chinese medicine composition can not produce drug resistance and is free of toxic and side effects and wide in application crowds, and the preparation method is simple and easy to operate and free of toxic and side effects.
Description
Technical field
The present invention relates to the field of Chinese medicines, specifically, relate to a kind of Chinese medicine composition of purulent meningitis sequela for the treatment of, and the preparation method of said composition.
Background technology
Purulent meningitis (purulent meningitis, abbreviationization brain) is to infect by various suppuration bacterium the meninges inflammation causing.Children's especially infant is common.Since using antibiotic, its case fatality rate is down to below 10% by 50%～90%, but still is one of children's's severe infections disease.Adult, also can be because the symptom such as flu causes purulent meningitis under the state of hypoimmunity, and wherein meningococcus causer is the most common, can occur popularly, and clinical manifestation has its particularity, title epidemic cerebrospinal meningitis.Epidemic cerebrospinal meningitis (abbreviation epidemic encephalitis) is the purulent meningitis being caused by meningococcus.Be more common in winter-spring season.Meningococcus is gram negative bacteria, invades human body by respiratory tract, produces a large amount of endotoxins in upper respiratory tract breeding, and time lower for the resistance, pathogen is invaded blood, then invades meninges, forms purulent meningitis.
At present, we treat purulent meningitis and adopt antibiotic therapy more, but it has also eliminated a part of beneficial bacteria in kill harmful antibacterial, make human body dysbacteriosis, cause body function disorder, more frighteningly life-time service antibiotic can make human body produce drug resistance, does not often reach expected effect in really needing antibiotic therapy.
Summary of the invention
In order to overcome above-mentioned deficiency, the object of the invention is to provide a kind of Chinese medicine composition for the treatment of purulent meningitis sequela and preparation method thereof, and this medicine can effectively improve the actual cure rate of purulent meningitis, does not produce drug resistance, have no side effect, be applicable to all kinds of crowds.
The present invention seeks to be achieved through the following technical solutions:
Think that through clinical observation for many years and experimental study the basic pathogenesis of purulent meningitis is due to affection due to external wind and heat, strongly fragrant and fire-transformation, mental activity disturbed by heat, hoodwinks thinking, occurs unconsciousness due to high fever; Pathogenic heat impairment of body fluid hematozemia, order loses and nourishes, therefore occur that sight is dark and gloomy, bradykinesia, lethargy; " tongue acting as the window of the heart "." words are the voice of the mind ", pathogenic heat impairment of body fluid is not multiple, and tongue is moving malfunctioning, thus tongue body vibration, aphasia; Pathogenic heat impairment of body fluid, crystal can not four cloth, and the heat body fluid that burns is expectorant, Phlegm to hinder collaterals, muscle arteries and veins loses in nourishing and makes moist, therefore occur that limbs flaccidity is soft, finger contracture; Red tongue is slightly purple, few tongue, and deep and weak pulse all belongs to resembling of yin deficiency and blood stasis.Stasis blocking channels, the suitable yin nourishing QI invigorating of the raw wind of the deficiency of YIN, clots absorbing dredging collateral.
Medicine of the present invention is made up of following raw materials according, Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli, Scorpio (parched).Radix Rehmanniae, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Angelicae Sinensis, Fructus Chaenomelis, Rhizoma Anemarrhenae YIN nourishing and the production of body fluid promoting in side, emergency relaxing muscles and tendons; Radix Paeoniae Rubra, Retinervus Luffae Fructus removing heat from blood and promoting blood circulation dredging collateral; The eleminating phlegm and freeing channels that relieves dizziness, high fever, infantile convulsions, epilepsy, etc. of Pheretima, Scorpio; The Radix Astragali, Radix Glycyrrhizae Preparata QI invigorating; Radix Salviae Miltiorrhizae blood circulation promoting competent silt; Herba Taxilli the lumbus strengthening and the kidney invigorating; The Ramulus Mori the meridian dredging that dispels the wind, reuses the Radix Astragali in side, gets its power obligate and walks, and the merit of all row whole bodies, to promote all medicine performance effect, passes unimpeded QI and blood, the stasis of blood ruton of dispelling.
Medicine of the present invention is made (consumption is weight portion) by following raw materials according
6～18 parts of Radix Rehmanniae, 5～15 parts of Radix Paeoniae Rubra, 5～15 parts of the Radix Paeoniae Albas, 6～18 parts of Radix Ophiopogonis, 3～8 parts of Radix Glycyrrhizae Preparatas, 5～15 parts of Radix Angelicae Sinensis, 15～45 parts of the Radixs Astragali, 5～15 parts of Pheretimas, 5～15 parts of Radix Salviae Miltiorrhizaes, 5～15 parts of Fructus Chaenomeliss, 5～15 parts of Retinervus Luffae Fructuss, 6～18 parts of Ramulus Moris, 5～15 parts of the Rhizoma Anemarrhenaes, 6～18 parts of Herba Taxillis, 3～8 parts of Scorpio (parched).
The preferred weight ratio range of preparation medicine of the present invention is:
8～14 parts of Radix Rehmanniae, 8～12 parts of Radix Paeoniae Rubra, 8～12 parts of the Radix Paeoniae Albas, 8～14 parts of Radix Ophiopogonis, 4～7 parts of Radix Glycyrrhizae Preparatas, 8～12 parts of Radix Angelicae Sinensis, 20～40 parts of the Radixs Astragali, 8～12 parts of Pheretimas, 8～12 parts of Radix Salviae Miltiorrhizaes, 8～12 parts of Fructus Chaenomeliss, 8～12 parts of Retinervus Luffae Fructuss, 8～14 parts of Ramulus Moris, 8～12 parts of the Rhizoma Anemarrhenaes, 8～14 parts of Herba Taxillis, 4～7 parts of Scorpio (parched).
The optimum weight proportioning of medicine of the present invention is:
12 parts of Radix Rehmanniae, 10 parts of Radix Paeoniae Rubra, 10 parts of the Radix Paeoniae Albas, 12 parts of Radix Ophiopogonis, 5 parts of Radix Glycyrrhizae Preparatas, 10 parts of Radix Angelicae Sinensis, 30 parts of the Radixs Astragali, 10 parts of Pheretimas, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Chaenomeliss, 10 parts of Retinervus Luffae Fructuss, 12 parts of Ramulus Moris, 10 parts of the Rhizoma Anemarrhenaes, 12 parts of Herba Taxillis, 5 parts of Scorpio (parched).
The preparation technology of medicine of the present invention: above-mentioned raw materials directly can be pulverized or through the conventional extractive technique in this area active component that obtains treating as the present invention purulent meningitis sequela medicine as refining in the extraction of decoction and alcohol sedimentation technique or ethanol extract from water precipitation.Described active component can be made various pharmaceutical formulations as powder, pill, tablet, granule, capsule etc. with pharmaceutically acceptable carrier or excipient composition.Wherein said pharmaceutically acceptable carrier or excipient are selected according to different dosage forms, and these carriers used or excipient can determine for the those of ordinary skill of pharmaceutical field.
Medicine of the present invention can be prepared according to following three kinds of methods:
First method, comprises the following steps:
(1) take raw materials of traditional Chinese medicinal materials according to above-mentioned consumption;
(2) above-mentioned Chinese crude drug is dried and crushed into fine powder, makes the dosage forms such as tablet, capsule, powder, pill, granule together with pharmaceutically acceptable excipient.
Second method, comprises the following steps:
(1) take raw materials of traditional Chinese medicinal materials according to above-mentioned consumption;
(2) Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary, each 1～1.5 hour, filter, collecting decoction, be concentrated into thick paste shape, make the dosage forms such as tablet, capsule, powder, pill, granule together with pharmaceutically acceptable excipient.
The invention has the beneficial effects as follows the actual cure rate that can improve purulent meningitis sequela, do not produce drug resistance, have no side effect, be suitable for crowd wide, preparation method is simple to operation.
The source of the Chinese crude drug that above-mentioned best preferred embodiment is mentioned is as follows:
Radix Rehmanniae: for the dried root of scrophulariaceae rehmannia glutinosa plant, sweet, cold.GUIXIN, liver, kidney channel have clearing away heat and cooling blood, and effect of YIN nourishing and the production of body fluid promoting, enters nutrient blood for heat, maculae caused by violent heat pathogen, and hematemesis and epistaxis, consumption of YIN caused by febrile disease, crimson tongue excessive thirst, constipation is hindered in Tianjin, fever due to yin deficiency, hectic fever due to YIN-deficiency consumptive fever, the interior-heat disease such as quench one's thirst.
Radix Paeoniae Rubra: be the dry root of ranunculaceae plant Radix Paeoniae.There is clearing away heat and cooling blood, effect of eliminating stasis to stop pain.Enter nutrient blood, maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, injury from falling down, the diseases such as carbuncle skin infection for heat.
The Radix Paeoniae Alba: be the dry root of ranunculaceae plant Radix Paeoniae.Bitter, acid, be slightly cold.Return liver, spleen channel.There is nourishing blood for regulating menstruation, astringing YIN to stop sweating, easing the affected liver to relieve pain, effect of suppressing liver-YANG.For blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat, hypochondriac pain, stomachache, limb pain twin, the dizzy disease of waiting of having a headache.
Radix Ophiopogonis: be the liliaceous plant dried root of Radix Ophiopogonis.There is YIN nourishing and the production of body fluid promoting, effect that lung moistening clears away heart-fire, for dryness of the lung dry cough, deficiency of YIN chronic cough, sore throat pharyngalgia, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, the diseases such as dryness of the intestine constipation.
Radix Glycyrrhizae Preparata: be the Preparation process product of Radix Glycyrrhizae.Sweet, flat.GUIXIN, lung, spleen, stomach warp, have spleen reinforcing stomach function regulating, effect of Yiqi and vein recovery.For weakness of the spleen and stomach, fatigue and weakness, severe palpitation, irregularly intermittent and regularly intermittent pulse.
Radix Angelicae Sinensis: be the dry root of umbelliferae angelica, having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, the diseases such as dryness of the intestine constipation.
The Radix Astragali: for the dry root of leguminous plant Radix Astagali or Radix Astragali, there is tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promotes the production of body fluid and nourishes blood, the stagnant blood stasis dispelling of row, expelling pus and toxin by strengthening QI, effect of expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, hemiplegia, arthralgia pain numbness, carbuncle is difficult bursts, and bursts for a long time and the disease such as does not hold back.
Pheretima: be the dry body of Ju Yin section animal Pheretima aspergillum, popular Pheretimatschiliensis, William Pheretimatschiliensis or the blind Pheretimatschiliensis of comb.Have heat clearing away arresting convulsion, dredging collateral, relievings asthma, effect of diuresis.Wrong for high heat god, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, the diseases such as edema oliguria.
Radix Salviae Miltiorrhizae: for dry root and the rhizome of labiate Radix Salviae Miltiorrhizae, there is blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, the relieving restlessness that clears away heart-fire, effect of removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, dysmenorrhea amenorrhea, skin infection swells and ache.
Fructus Chaenomelis: be the dry almost ripe fruit of rosaceous plant chaenomeles lagenaria.There is relaxing muscles and tendons and activating QI and blood in the collateral, effect of stomach function regulating removing dampness.For arthralgia chiefly caused by damp pathogen contracture, the heavy pain of waist knee joint acid, heat-damp in summer is vomited and diarrhoea, convulsion spasm and pain, the diseases such as beriberi edema.
Retinervus Luffae Fructus: for the vascular bundle of the dry mature fruit of cucurbitaceous plant Fructus Luffae, have and dispel the wind, dredging collateral, invigorates blood circulation, effect of stimulating milk secretion.For arthralgia pain contracture, distending pain in the chest and hypochondrium, newborn antiperspirant is obstructed, the acute mastitis disease such as swell and ache.
Ramulus Mori: be the dry twig of moraceae plants Mulberry.There is wind-damp dispelling, the effect in sharp joint, for Bi condition, the diseases such as shoulder arm, joint aches numbness.
The Rhizoma Anemarrhenae: be the dry rhizome of the liliaceous plant Rhizoma Anemarrhenae.There is clearing away heat-fire, nourshing Yin and drynsessmoistening prescription effect.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, the disease such as interior-heat is quenched one's thirst, dryness of the intestine constipation.
Herba Taxilli: be the dry stem and branch with leaf of Loranthaceae plant Herba Taxilli.There is wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, effect of antiabortive unit.For rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, and metrorrhagia is through many, blood leaking in gestation, frequent fetal movement, the disease such as have a dizzy spell.
Scorpio (parched): be the dry processed goods of Scorpio.There is endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain, effect of dispersing pathogen accumulation.For liver-wind stirring up internally, spasm is twitched, infantile convulsion, hemiplegia, tetanus, rheumatic arthralgia, migraine and general headache, skin infection, the diseases such as scrofula.
Detailed description of the invention
This pharmaceutical composition and preparation method thereof is as follows:
Embodiment 1: the preparation of pill
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 6 parts of Radix Rehmanniae, 5 parts of Radix Paeoniae Rubra, 5 parts of the Radix Paeoniae Albas, 6 parts of Radix Ophiopogonis, 3 parts of Radix Glycyrrhizae Preparatas, 5 parts of Radix Angelicae Sinensis, 15 parts of the Radixs Astragali, 5 parts of Pheretimas, 5 parts of Radix Salviae Miltiorrhizaes, 5 parts of Fructus Chaenomeliss, 5 parts of Retinervus Luffae Fructuss, 6 parts of Ramulus Moris, 5 parts of the Rhizoma Anemarrhenaes, 6 parts of Herba Taxillis, 3 parts of Scorpio (parched), Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary, each 1～1.5 hour, filter, collecting decoction, be concentrated into thick paste shape, add Scorpio fine powder to mix, dry, be ground into fine powder, mix, the general micropill of making of water, uses Pulvis Fumi Carbonisatus coating, hit light, dry making.
Embodiment 2: the preparation of pill
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 18 parts of Radix Rehmanniae, 15 parts of Radix Paeoniae Rubra, 15 parts of the Radix Paeoniae Albas, 18 parts of Radix Ophiopogonis, 8 parts of Radix Glycyrrhizae Preparatas, 15 parts of Radix Angelicae Sinensis, 45 parts of the Radixs Astragali, 15 parts of Pheretimas, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Fructus Chaenomeliss, 15 parts of Retinervus Luffae Fructuss, 18 parts of Ramulus Moris, 15 parts of the Rhizoma Anemarrhenaes, 18 parts of Herba Taxillis, 8 parts of Scorpio (parched), Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary, each 1～1.5 hour, filter, collecting decoction, be concentrated into thick paste shape, add Scorpio fine powder to mix, dry, be ground into fine powder, mix, the general micropill of making of water, uses Pulvis Fumi Carbonisatus coating, hit light, dry making.
Embodiment 3: the preparation of pill
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 12 parts of Radix Rehmanniae, 10 parts of Radix Paeoniae Rubra, 10 parts of the Radix Paeoniae Albas, 12 parts of Radix Ophiopogonis, 5 parts of Radix Glycyrrhizae Preparatas, 10 parts of Radix Angelicae Sinensis, 30 parts of the Radixs Astragali, 10 parts of Pheretimas, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Chaenomeliss, 10 parts of Retinervus Luffae Fructuss, 12 parts of Ramulus Moris, 10 parts of the Rhizoma Anemarrhenaes, 12 parts of Herba Taxillis, 5 parts of Scorpio (parched).Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary, each 1～1.5 hour, filter, collecting decoction, be concentrated into thick paste shape, add Scorpio fine powder to mix, dry, be ground into fine powder, mix, the general micropill of making of water, uses Pulvis Fumi Carbonisatus coating, hit light, dry making.
Embodiment 4: the preparation of pill
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 12 parts of Radix Rehmanniae, 10 parts of Radix Paeoniae Rubra, 10 parts of the Radix Paeoniae Albas, 12 parts of Radix Ophiopogonis, 5 parts of Radix Glycyrrhizae Preparatas, 10 parts of Radix Angelicae Sinensis, 30 parts of the Radixs Astragali, 10 parts of Pheretimas, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Chaenomeliss, 10 parts of Retinervus Luffae Fructuss, 12 parts of Ramulus Moris, 10 parts of the Rhizoma Anemarrhenaes, 12 parts of Herba Taxillis, 5 parts of Scorpio (parched).Above-mentioned Chinese crude drug is dried and crushed into fine powder, and the general micropill of making of water, uses Pulvis Fumi Carbonisatus coating, hits light, dry making.
Embodiment 5: the preparation of tablet
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 6 parts of Radix Rehmanniae, 5 parts of Radix Paeoniae Rubra, 5 parts of the Radix Paeoniae Albas, 6 parts of Radix Ophiopogonis, 3 parts of Radix Glycyrrhizae Preparatas, 5 parts of Radix Angelicae Sinensis, 15 parts of the Radixs Astragali, 5 parts of Pheretimas, 5 parts of Radix Salviae Miltiorrhizaes, 5 parts of Fructus Chaenomeliss, 5 parts of Retinervus Luffae Fructuss, 6 parts of Ramulus Moris, 5 parts of the Rhizoma Anemarrhenaes, 6 parts of Herba Taxillis, 3 parts of Scorpio (parched), Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary; each 1～1.5 hour, filter collecting decoction; be concentrated into thick paste shape; add Scorpio fine powder to mix, dry, pulverize into fine powder; mix homogeneously; add appropriate adjuvant, granulation mixes, and compacting in flakes.
Embodiment 6: the preparation of tablet
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 18 parts of Radix Rehmanniae, 15 parts of Radix Paeoniae Rubra, 15 parts of the Radix Paeoniae Albas, 18 parts of Radix Ophiopogonis, 8 parts of Radix Glycyrrhizae Preparatas, 15 parts of Radix Angelicae Sinensis, 45 parts of the Radixs Astragali, 15 parts of Pheretimas, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Fructus Chaenomeliss, 15 parts of Retinervus Luffae Fructuss, 18 parts of Ramulus Moris, 15 parts of the Rhizoma Anemarrhenaes, 18 parts of Herba Taxillis, 8 parts of Scorpio (parched), Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary, each 1～1.5 hour, filter, collecting decoction, be concentrated into thick paste shape, add Scorpio fine powder to mix, dry, pulverize into fine powder; Add appropriate adjuvant, mix, granulate, compacting in flakes.
Embodiment 7: the preparation of tablet
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 12 parts of Radix Rehmanniae, 10 parts of Radix Paeoniae Rubra, 10 parts of the Radix Paeoniae Albas, 12 parts of Radix Ophiopogonis, 5 parts of Radix Glycyrrhizae Preparatas, 10 parts of Radix Angelicae Sinensis, 30 parts of the Radixs Astragali, 10 parts of Pheretimas, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Chaenomeliss, 10 parts of Retinervus Luffae Fructuss, 12 parts of Ramulus Moris, 10 parts of the Rhizoma Anemarrhenaes, 12 parts of Herba Taxillis, 5 parts of Scorpio (parched).Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary, each 1～1.5 hour, filter, collecting decoction, be concentrated into thick paste shape, add Scorpio fine powder to mix, dry, pulverize into fine powder.Add appropriate adjuvant, mix, granulate, compacting in flakes.
Embodiment 8: the preparation of tablet
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 12 parts of Radix Rehmanniae, 10 parts of Radix Paeoniae Rubra, 10 parts of the Radix Paeoniae Albas, 12 parts of Radix Ophiopogonis, 5 parts of Radix Glycyrrhizae Preparatas, 10 parts of Radix Angelicae Sinensis, 30 parts of the Radixs Astragali, 10 parts of Pheretimas, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Chaenomeliss, 10 parts of Retinervus Luffae Fructuss, 12 parts of Ramulus Moris, 10 parts of the Rhizoma Anemarrhenaes, 12 parts of Herba Taxillis, 5 parts of Scorpio (parched), above-mentioned Chinese crude drug is dried and crushed into fine powder, add appropriate adjuvant, mix, granulate, compacting in flakes.
Embodiment 9: the preparation of powder
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 6 parts of Radix Rehmanniae, 5 parts of Radix Paeoniae Rubra, 5 parts of the Radix Paeoniae Albas, 6 parts of Radix Ophiopogonis, 3 parts of Radix Glycyrrhizae Preparatas, 5 parts of Radix Angelicae Sinensis, 15 parts of the Radixs Astragali, 5 parts of Pheretimas, 5 parts of Radix Salviae Miltiorrhizaes, 5 parts of Fructus Chaenomeliss, 5 parts of Retinervus Luffae Fructuss, 6 parts of Ramulus Moris, 5 parts of the Rhizoma Anemarrhenaes, 6 parts of Herba Taxillis, 3 parts of Scorpio (parched), Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary, each 1～1.5 hour, filter, collecting decoction, be concentrated into thick paste shape, add Scorpio fine powder to mix, dry, be ground into fine powder, make.
Embodiment 10: the preparation of powder
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 18 parts of Radix Rehmanniae, 15 parts of Radix Paeoniae Rubra, 15 parts of the Radix Paeoniae Albas, 18 parts of Radix Ophiopogonis, 8 parts of Radix Glycyrrhizae Preparatas, 15 parts of Radix Angelicae Sinensis, 45 parts of the Radixs Astragali, 15 parts of Pheretimas, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Fructus Chaenomeliss, 15 parts of Retinervus Luffae Fructuss, 18 parts of Ramulus Moris, 15 parts of the Rhizoma Anemarrhenaes, 18 parts of Herba Taxillis, 8 parts of Scorpio (parched), Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary, each 1～1.5 hour, filter, collecting decoction, be concentrated into thick paste shape, add Scorpio fine powder to mix, dry, pulverize into fine powder and make.
Embodiment 11: the preparation of powder
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 12 parts of Radix Rehmanniae, 10 parts of Radix Paeoniae Rubra, 10 parts of the Radix Paeoniae Albas, 12 parts of Radix Ophiopogonis, 5 parts of Radix Glycyrrhizae Preparatas, 10 parts of Radix Angelicae Sinensis, 30 parts of the Radixs Astragali, 10 parts of Pheretimas, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Chaenomeliss, 10 parts of Retinervus Luffae Fructuss, 12 parts of Ramulus Moris, 10 parts of the Rhizoma Anemarrhenaes, 12 parts of Herba Taxillis, 5 parts of Scorpio (parched).Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary, each 1～1.5 hour, filter, collecting decoction, be concentrated into thick paste shape, add Scorpio fine powder to mix, dry, pulverize into fine powder and make.
Embodiment 12: the preparation of powder
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 12 parts of Radix Rehmanniae, 10 parts of Radix Paeoniae Rubra, 10 parts of the Radix Paeoniae Albas, 12 parts of Radix Ophiopogonis, 5 parts of Radix Glycyrrhizae Preparatas, 10 parts of Radix Angelicae Sinensis, 30 parts of the Radixs Astragali, 10 parts of Pheretimas, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Chaenomeliss, 10 parts of Retinervus Luffae Fructuss, 12 parts of Ramulus Moris, 10 parts of the Rhizoma Anemarrhenaes, 12 parts of Herba Taxillis, 5 parts of Scorpio (parched), be dried and crushed into fine powder by above-mentioned Chinese crude drug and make.
Embodiment 13: the preparation of capsule
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 6 parts of Radix Rehmanniae, 5 parts of Radix Paeoniae Rubra, 5 parts of the Radix Paeoniae Albas, 6 parts of Radix Ophiopogonis, 3 parts of Radix Glycyrrhizae Preparatas, 5 parts of Radix Angelicae Sinensis, 15 parts of the Radixs Astragali, 5 parts of Pheretimas, 5 parts of Radix Salviae Miltiorrhizaes, 5 parts of Fructus Chaenomeliss, 5 parts of Retinervus Luffae Fructuss, 6 parts of Ramulus Moris, 5 parts of the Rhizoma Anemarrhenaes, 6 parts of Herba Taxillis, 3 parts of Scorpio (parched), Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary, each 1～1.5 hour, filter, collecting decoction, is concentrated into thick paste shape, adds Scorpio fine powder to mix, dry, be ground into fine powder, mix homogeneously, packs hard capsule case into.
Embodiment 14: the preparation of capsule
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 18 parts of Radix Rehmanniae, 15 parts of Radix Paeoniae Rubra, 15 parts of the Radix Paeoniae Albas, 18 parts of Radix Ophiopogonis, 8 parts of Radix Glycyrrhizae Preparatas, 15 parts of Radix Angelicae Sinensis, 45 parts of the Radixs Astragali, 15 parts of Pheretimas, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Fructus Chaenomeliss, 15 parts of Retinervus Luffae Fructuss, 18 parts of Ramulus Moris, 15 parts of the Rhizoma Anemarrhenaes, 18 parts of Herba Taxillis, 8 parts of Scorpio (parched), Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary, each 1～1.5 hour, filter, collecting decoction, be concentrated into thick paste shape, add Scorpio fine powder to mix, dry, be ground into fine powder, pack hard capsule case into.
Embodiment 15: the preparation of capsule
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 12 parts of Radix Rehmanniae, 10 parts of Radix Paeoniae Rubra, 10 parts of the Radix Paeoniae Albas, 12 parts of Radix Ophiopogonis, 5 parts of Radix Glycyrrhizae Preparatas, 10 parts of Radix Angelicae Sinensis, 30 parts of the Radixs Astragali, 10 parts of Pheretimas, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Chaenomeliss, 10 parts of Retinervus Luffae Fructuss, 12 parts of Ramulus Moris, 10 parts of the Rhizoma Anemarrhenaes, 12 parts of Herba Taxillis, 5 parts of Scorpio (parched).Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary, each 1～1.5 hour, filter, collecting decoction, be concentrated into thick paste shape, add Scorpio fine powder to mix, dry, be ground into fine powder, pack hard capsule case into.
Embodiment 16: the preparation of capsule
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 12 parts of Radix Rehmanniae, 10 parts of Radix Paeoniae Rubra, 10 parts of the Radix Paeoniae Albas, 12 parts of Radix Ophiopogonis, 5 parts of Radix Glycyrrhizae Preparatas, 10 parts of Radix Angelicae Sinensis, 30 parts of the Radixs Astragali, 10 parts of Pheretimas, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Chaenomeliss, 10 parts of Retinervus Luffae Fructuss, 12 parts of Ramulus Moris, 10 parts of the Rhizoma Anemarrhenaes, 12 parts of Herba Taxillis, 5 parts of Scorpio (parched), above-mentioned Chinese crude drug is dried and crushed into fine powder, packs hard capsule case into.
Embodiment 17: the preparation of granule
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 6 parts of Radix Rehmanniae, 5 parts of Radix Paeoniae Rubra, 5 parts of the Radix Paeoniae Albas, 6 parts of Radix Ophiopogonis, 3 parts of Radix Glycyrrhizae Preparatas, 5 parts of Radix Angelicae Sinensis, 15 parts of the Radixs Astragali, 5 parts of Pheretimas, 5 parts of Radix Salviae Miltiorrhizaes, 5 parts of Fructus Chaenomeliss, 5 parts of Retinervus Luffae Fructuss, 6 parts of Ramulus Moris, 5 parts of the Rhizoma Anemarrhenaes, 6 parts of Herba Taxillis, 3 parts of Scorpio (parched), Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary, each 1～1.5 hour, filter collecting decoction, be concentrated into thick paste shape, add Scorpio fine powder to mix, dry, pulverize into fine powder, mix homogeneously, add appropriate adjuvant, mix, granulation.
Embodiment 18: the preparation of granule
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 18 parts of Radix Rehmanniae, 15 parts of Radix Paeoniae Rubra, 15 parts of the Radix Paeoniae Albas, 18 parts of Radix Ophiopogonis, 8 parts of Radix Glycyrrhizae Preparatas, 15 parts of Radix Angelicae Sinensis, 45 parts of the Radixs Astragali, 15 parts of Pheretimas, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Fructus Chaenomeliss, 15 parts of Retinervus Luffae Fructuss, 18 parts of Ramulus Moris, 15 parts of the Rhizoma Anemarrhenaes, 18 parts of Herba Taxillis, 8 parts of Scorpio (parched), Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary, each 1～1.5 hour, filter, collecting decoction, be concentrated into thick paste shape, add Scorpio fine powder to mix, dry, pulverize into fine powder; Add appropriate adjuvant, mix, granulation.
Embodiment 19: the preparation of granule
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 12 parts of Radix Rehmanniae, 10 parts of Radix Paeoniae Rubra, 10 parts of the Radix Paeoniae Albas, 12 parts of Radix Ophiopogonis, 5 parts of Radix Glycyrrhizae Preparatas, 10 parts of Radix Angelicae Sinensis, 30 parts of the Radixs Astragali, 10 parts of Pheretimas, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Chaenomeliss, 10 parts of Retinervus Luffae Fructuss, 12 parts of Ramulus Moris, 10 parts of the Rhizoma Anemarrhenaes, 12 parts of Herba Taxillis, 5 parts of Scorpio (parched).Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary, each 1～1.5 hour, filter, collecting decoction, be concentrated into thick paste shape, add Scorpio fine powder to mix, dry, pulverize into fine powder.Add appropriate adjuvant, mix, granulation.
Embodiment 20: the preparation of granule
Take these raw materials of traditional Chinese medicinal materials according to following consumption: 12 parts of Radix Rehmanniae, 10 parts of Radix Paeoniae Rubra, 10 parts of the Radix Paeoniae Albas, 12 parts of Radix Ophiopogonis, 5 parts of Radix Glycyrrhizae Preparatas, 10 parts of Radix Angelicae Sinensis, 30 parts of the Radixs Astragali, 10 parts of Pheretimas, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Chaenomeliss, 10 parts of Retinervus Luffae Fructuss, 12 parts of Ramulus Moris, 10 parts of the Rhizoma Anemarrhenaes, 12 parts of Herba Taxillis, 5 parts of Scorpio (parched), above-mentioned Chinese crude drug is dried and crushed into fine powder, add appropriate adjuvant, mix granulation.
The raw wind of the pharmaceutical treatment deficiency of YIN that Chinese medicine composition of the present invention or its extract are made as active component, the purulent meningitis sequela total effective rate of stasis blocking channels are 89.6%.Prove through clinical trial for many years, the preparation of pharmaceutical composition of the present invention is fairly obvious to purulent meningitis sequela curative effect, refers to following experiment.
(1) clinical effect trial of the present invention to treatment purulent meningitis sequela
1. method: accept altogether 48 routine purulent meningitis sequela patients and receive treatment, child's 35 examples, adult's 13 examples, average 41 years old, wherein plain edition 25 examples, fulminant type 16 examples, chronic septicemia type 7 examples, all patients all do hemogram checking.Treatment gives medicine of the present invention, and each 3-5g, every day 3 times, 5 days is a course for the treatment of.
2. efficacy determination:
(1) symptom is improved degree:
Plain edition: Acute onset, upper respiratory tract infection symptoms, as pharyngalgia, watery nasal discharge, enters deteriorated blood after date and occur high heat, fear of cold, shiver with cold.70% the mucocutaneous appearance of case is dark or aubergine differs in size, the petechia of skewness, ecchymosis.After 1～2 day, enter the meningitis phase, occur intracranial hypertension, show as headache aggravation, vomiting frequent (being spurting) and meningismus (are stiffness of the neck, opisthotonus, the brudzinski's sign positive), hypertension, often keeps in dark place, mad dry even respiratory failure etc.General pain dysphoria and the toxemia performance such as have a dull expression on one's face, there is delirium, stupor in severe patient.Because of skull suture and fontanel patent, meningitis symptom is not often true to type infant (2 years old following), shows as high heat, vomiting, refusing to eat, the uneasiness of crying and screaming, and even faints from fear, though without meningeal irritation sign, anterior anus is full.
Fulminant type: this kind of is more common in child, state of an illness ferociousness, can be dead in 24 hours as rescued not in time.Chang Gaore, headache, vomiting, serious lethargy, disturbance of consciousness, time have convulsions, oliguria or anuria, suffer from brain material injury patient and enter rapidly stupor, frequent convulsion, hemiplegia of limb, hypertension, a side platycoria, disappears to luminous reflectance, and eyeball is fixing there is respiratory failure and death very soon.This kind of is divided into again and breaks out shock type and break out encephalitis type.Body gram type is except plain edition symptom, and its outstanding behaviours is whole body poisoning symptom, and spirit is extremely withered and rubbed, and has pale complexion, cold limbs, and there is decorative pattern in skin, hypourocrinia, blood pressure drops, cerebrospinal fluid is clarified more, and cell number slightly increases or is normal.Hemoculture and petechiae smear are positive.Break out encephalitis type, its outstanding behaviours is severe headache, dysphoria, and frequently vomiting, twitches, and, finally there is cerebral hernia, respiratory failure in stupor rapidly.Have shock type and encephalitis type symptom for mixed type, case fatality rate is high simultaneously.
Chronic septicemia type: mostly be adult, the delay several months long, generating heat, erythra, arthropathy have hepatomegaly as feature, minority, repeatedly hemoculture lofty perch smear can find pathogen
Cure: refer to that more than 95% original symptom obviously alleviates;
Significantly effectively: more than 75% original symptom obviously alleviates;
Effective: to refer to that more than 50% original symptom obviously alleviates;
Invalid: to refer to that original symptom below 50% alleviates or complete nothing alleviates.
3. clinical observation result
Modern medicine study confirmation, medicine of the present invention can effectively alleviate the symptoms such as high heat, headache, pharyngalgia, vomiting, improves disturbance of consciousness, faint from fear, oliguria or anuria, stupor, hemiplegia of limb, hypertension, a side platycoria, the symptoms such as erythra.
After taking medicine 10 days, patient's clinical symptoms improvement situation is in table 1:
Wang, female, 50 years old, lives Hegang City Nanshan District, because catching a cold, the two ears pain of successively suppurating, a severe pain, nausea and vomiting, coma due to high fever, hospital diagnosis is purulent meningitis, through moving back by hyperpyrexia after antibiotic etc treatment, god knows gradually clear, find again tongue body vibration, the diseases such as babble, are diagnosed as meningitis sequela, treat more than 20, without being clearly better, card is shown in that sight is dark and gloomy, bradykinesia, lethargy, tongue body vibration, aphasia, left side upper and lower extremities flaccidity is soft, and the right hand refers to contracture; Body of the tongue is slightly purple, few tongue, deep and weak pulse.Take medicine of the present invention potion on the one, serve on after three doses, freely, the right hand refers to that contracture stops to upper left lower limb exercise.Serve on again five doses, lamprophonia, body is refreshing, has to the trend that heals.Serve on again 15 doses, all diseases disappear entirely, and rehabilitation is as usual.After 1 year, follow up a case by regular visits to not recurrence again.
Claims (5)
1. treat a Chinese medicine composition for purulent meningitis sequela, it is characterized in that it is the medicament of being made up of the pharmacodynamic raw materials of following weight portion and pharmaceutically acceptable carrier or excipient:
6～18 parts of Radix Rehmanniae, 5～15 parts of Radix Paeoniae Rubra, 5～15 parts of the Radix Paeoniae Albas, 6～18 parts of Radix Ophiopogonis, 3～8 parts of Radix Glycyrrhizae Preparatas, 5～15 parts of Radix Angelicae Sinensis, 15～45 parts of the Radixs Astragali, 5～15 parts of Pheretimas, 5～15 parts of Radix Salviae Miltiorrhizaes, 5～15 parts of Fructus Chaenomeliss, 5～15 parts of Retinervus Luffae Fructuss, 6～18 parts of Ramulus Moris, 5～15 parts of the Rhizoma Anemarrhenaes, 6～18 parts of Herba Taxillis, 3～8 parts of Scorpio (parched).
2. treat a Chinese medicine composition for purulent meningitis sequela, it is characterized in that it is the medicament of being made up of the pharmacodynamic raw materials of following weight portion and pharmaceutically acceptable carrier or excipient:
8～14 parts of Radix Rehmanniae, 8～12 parts of Radix Paeoniae Rubra, 8～12 parts of the Radix Paeoniae Albas, 8～14 parts of Radix Ophiopogonis, 4～7 parts of Radix Glycyrrhizae Preparatas, 8～12 parts of Radix Angelicae Sinensis, 20～40 parts of the Radixs Astragali, 8～12 parts of Pheretimas, 8～12 parts of Radix Salviae Miltiorrhizaes, 8～12 parts of Fructus Chaenomeliss, 8～12 parts of Retinervus Luffae Fructuss, 8～14 parts of Ramulus Moris, 8～12 parts of the Rhizoma Anemarrhenaes, 8～14 parts of Herba Taxillis, 4～7 parts of Scorpio (parched).
3. treat a Chinese medicine composition for purulent meningitis sequela, it is characterized in that it is the medicament of being made up of the pharmacodynamic raw materials of following weight portion and pharmaceutically acceptable carrier or excipient:
12 parts of Radix Rehmanniae, 10 parts of Radix Paeoniae Rubra, 10 parts of the Radix Paeoniae Albas, 12 parts of Radix Ophiopogonis, 5 parts of Radix Glycyrrhizae Preparatas, 10 parts of Radix Angelicae Sinensis, 30 parts of the Radixs Astragali, 10 parts of Pheretimas, 10 parts of Radix Salviae Miltiorrhizaes, 10 parts of Fructus Chaenomeliss, 10 parts of Retinervus Luffae Fructuss, 12 parts of Ramulus Moris, 10 parts of the Rhizoma Anemarrhenaes, 12 parts of Herba Taxillis, 5 parts of Scorpio (parched).
4. the preparation method of a kind of Chinese medicine composition for the treatment of purulent meningitis sequela as described in claim 1～3 any one, is characterized in that comprising the following steps:
(1) take raw materials of traditional Chinese medicinal materials according to above-mentioned consumption;
(2) above-mentioned Chinese crude drug is dried and crushed into fine powder, makes tablet, capsule, powder, pill, granule together with pharmaceutically acceptable excipient.
5. the preparation method of a kind of Chinese medicine composition for the treatment of purulent meningitis sequela as described in claim 1～3 any one, is characterized in that comprising the following steps:
(1) take raw materials of traditional Chinese medicinal materials according to above-mentioned consumption;
(2) Scorpio (parched) is ground into fine powder, sieves; Radix Rehmanniae, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Radix Ophiopogonis, Radix Glycyrrhizae Preparata, Radix Angelicae Sinensis, the Radix Astragali, Pheretima, Radix Salviae Miltiorrhizae, Fructus Chaenomelis, Retinervus Luffae Fructus, Ramulus Mori, the Rhizoma Anemarrhenae, Herba Taxilli are decocted with water to secondary, each 1～1.5 hour, filter, collecting decoction, be concentrated into thick paste shape, make tablet, capsule, powder, pill, granule together with pharmaceutically acceptable excipient.
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