CN104257840A - Pharmaceutical composition for treating eczema of infants and young children and preparation method of pharmaceutical composition - Google Patents
Pharmaceutical composition for treating eczema of infants and young children and preparation method of pharmaceutical composition Download PDFInfo
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Abstract
The invention discloses a pharmaceutical composition for treating eczema of infants and young children and a preparation method of the pharmaceutical composition. The composition is prepared from radix arnebiae seu lithospermi, folium artemisiae argyi, honeysuckle, cortex fraxini, cortex phellodendri, radix scutellariae, herba houttuyniae, gypsum and borneol. The pharmaceutical composition for treating eczema of infants and young children has the characteristics of good effect, no toxic and side effects and the like, and is safe to use. Trials show that the composition is good in both hardness and skin touch feeling, and is suitable for external use for skins of the infants and young children.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition for the treatment of infant eczema and preparation method thereof, belong to medical art.
Background technology
Infant eczema is a kind of allergic skin disease, is common clinical, and the traditional Chinese medical science is called tire leprosy, infantile eczema, erythroderma of newborn etc.Clinical symptoms, with local erythema, pimple, vesicle, has juice etc., and with violent pruritus, the wet eczema that all can make of heat, chance shows significantly.Primary disease pruritus difficulty is delayed, and touching difficulty heals, and easy recurrent exerbation, make infant emotion uneasy and impact sleep and diet, and secondary bacterial infection, hinder normal growth growth and health.
At present outer method of the preventing and treating treatment be coated with for oral administration is generally adopted to the treatment of this disease, and clinically in medicine for external use often containing glucocorticoids medicine or histamine class antiallergic agent, side effect is more, easily causes whole body or local untoward reaction, and treatment natural law can not be long.
Summary of the invention
In order to overcome the deficiencies in the prior art, the invention provides a kind of pharmaceutical composition for the treatment of infant eczema, this pharmaceutical composition is effective, use safety, to have no side effect.Present invention also offers the preparation method of this pharmaceutical composition.
Technical scheme of the present invention is as follows:
Treat a pharmaceutical composition for infant eczema, said composition is made up of the crude drug of following weight portion: Radix Arnebiae (Radix Lithospermi) 50-100 part, Folium Artemisiae Argyi 100-150 part, Flos Lonicerae 50-100 part, Cortex Fraxini 50-80 part, Cortex Phellodendri 20-40 part, Radix Scutellariae 20-40 part, Herba Houttuyniae 10-20 part, Gypsum Fibrosum 20-30 part, Borneolum Syntheticum 4-10 part.
The present invention is preferred, the pharmaceutical composition of above-mentioned treatment infant eczema, is made up of the crude drug of following weight portion: Radix Arnebiae (Radix Lithospermi) 80 parts, Folium Artemisiae Argyi 120 parts, Flos Lonicerae 70 parts, Cortex Fraxini 60 parts, Cortex Phellodendri 30 parts, Radix Scutellariae 25 parts, Herba Houttuyniae 15 parts, 25 parts, Gypsum Fibrosum, Borneolum Syntheticum 5 parts.
Present invention also offers the preparation method of the pharmaceutical composition of this treatment infant eczema, step is as follows:
1) dried cream powder is prepared: after Folium Artemisiae Argyi, Flos Lonicerae, Cortex Phellodendri, Radix Scutellariae, Herba Houttuyniae, Gypsum Fibrosum powder are broken into coarse powder, add ethanol extraction 2-3 time of percent by volume 35-65%, the ethanol contend at every turn added is the 6-10 times amount of medical material weight, each extraction 1-2h, extracting solution merges and filters and concentrate, dry, pulverize, and get dry extract powder I;
Or: after Cortex Fraxini is ground into coarse powder together with Folium Artemisiae Argyi, Flos Lonicerae, Cortex Phellodendri, Radix Scutellariae, Herba Houttuyniae, Gypsum Fibrosum powder, obtain the dried cream powder II containing Cortex Fraxini by above-mentioned steps;
2) prepare oil immersion thing: Radix Arnebiae (Radix Lithospermi) is ground into coarse powder, and add Semen Lini oil, the refine Adeps Caprae seu ovis miscella immersion 3-10 day of medical material 3-7 times weight, then slow fire decocts 1-2h, filters while hot, obtains oil immersion thing I;
Or: by Cortex Fraxini together with Radix Arnebiae (Radix Lithospermi), obtain the oil immersion thing II containing Cortex Fraxini by above-mentioned steps;
3) mix: get step 2) the obtained oil immersion thing II containing Cortex Fraxini, temperature is cooled to 50 DEG C, adds step 1) obtained not containing the dried cream powder I of Cortex Fraxini, stir, and polish 2 times with colloid mill, finally add Borneolum Syntheticum, mix homogeneously, obtains pharmaceutical composition of the present invention;
Or: get step 2) obtained not containing oil immersion thing I and the step 1 of Cortex Fraxini) the obtained dried cream powder II containing Cortex Fraxini, obtain pharmaceutical composition of the present invention by above-mentioned steps.
The present invention is preferred, in the preparation method of described pharmaceutical composition, step 1) described in the method preparing dried cream powder be: after described crude drug is ground into coarse powder, add the ethanol extraction 2 times of percent by volume 50%, the ethanol contend at every turn added is 7 times amount of medical material weight, each extraction 2h, extracting solution merges and filters and concentrate, dry, pulverize, and get dry extract powder I or II.
The present invention is preferred further, in the preparation method of described pharmaceutical composition, step 2) described in the method preparing oil immersion thing be: described crude drug is ground into coarse powder, and add the Semen Lini oil of medical material 6 times of weight, refine Adeps Caprae seu ovis miscella soaks 5, slow fire decocts 2h again, filter while hot, obtain oil immersion thing I or II.
Further, in the preparation method of pharmaceutical composition of the present invention, step 2) described in Semen Lini oil, refine Adeps Caprae seu ovis miscella weight ratio be 2:1.
The unit corresponding relation of volume of the present invention and weight is mL:g or L:kg.
Beneficial effect: the pharmaceutical composition for the treatment of infant eczema provided by the invention, has effective, use safety, the feature such as has no side effect.The present invention is found by test, and when the ratio of Semen Lini oil and refine Adeps Caprae seu ovis is 2: 1, gained mixture no matter hardness, contact skin sense or half way freezing point is all better, is applicable to infant external preparation for skin, and the extraction to Cortex Fraxini, the effect of oil immersion is better than alcohol extraction.
Detailed description of the invention:
Below in conjunction with experimental example and embodiment, the present invention is further illustrated.
The selection of experimental example 1, miscella
Adeps Caprae seu ovis is fine and smooth, contact skin sense is good, but freezing point is higher, is unfavorable for preparation; Semen Lini oil freezing point is lower, but contact skin is too greasy.Consider the two mixing to extract Radix Arnebiae (Radix Lithospermi) for this reason, and with the ratio that contact skin sense and fusing point are both choose targets.
One, test material and sample
Refine Adeps Caprae seu ovis (He'nan Yisai Beef (Stock) Co., Ltd. produces, lot number 2013120908X), Semen Lini oil (Huajian, Datong oils and fats Co., Ltd produces, lot number 20140211)
Two, test method
The miscella of configuration Different Weight ratio, add 8g Radix Arnebiae (Radix Lithospermi) coarse powder, 6g Cortex Fraxini coarse powder, soak 5, slow fire decocts 2h again, filter while hot, add embodiment 1 step 1) the dried cream powder 20g for preparing, colloid mill is polished 2 times, Slow cooling, writes down half way freezing point (namely having solidified the temperature of 1/2), after solidifying completely, gained mixture is applied on skin, according to the hardness of mixture with give a mark respectively with the contiguous sense of skin, hardness score value according to contact skin, suitable 5 points of soft or hard, cross 3 points soft or really up to the mark, too soft or too hard 1 point; To give a mark score value with the contiguous sense of skin: lubricate non-greasy to greasy not dry and comfortable from exquisiteness, score value is respectively 5 ~ 1.
Three, result of the test: in table 1.
The investigation of table 1 difference mixing oil ratio example
According to upper table, when the ratio of Semen Lini oil and refine Adeps Caprae seu ovis is 2:1, gained mixture no matter hardness, contact skin sense or half way freezing point is all better, is applicable to infant external preparation for skin.
Experimental example 2, clinical data
One, case selection
Choose 78 routine infant eczema infants, man 38 example, female 40 example; 3 months ages ~ 2 years old 8 months, 1 years old 3 months mean age, main clinical manifestation: face, cervical region and other area skin erythra of whole body, red pimple, erythema, vesicle and silly skin, ooze out, rotten to the corn, and with pruritus in various degree.
Two, sample preparation
1, sample 1:
1) dried cream powder is prepared: after Folium Artemisiae Argyi 120g, Flos Lonicerae 70g, Cortex Phellodendri 30g, Radix Scutellariae 25g, Herba Houttuyniae 15g, Gypsum Fibrosum 25g are ground into coarse powder, add the ethanol extraction 2 times of percent by volume 50%, the ethanol contend at every turn added is 7 times amount of medical material weight, each extraction 2h, extracting solution merges and filters and concentrate, dry, pulverize, and get dry extract powder 23g;
2) prepare oil immersion thing: Radix Arnebiae (Radix Lithospermi), Cortex Fraxini are ground into coarse powder, and add medical material 6 times of weight, Semen Lini oil that weight ratio is 2:1, refine Adeps Caprae seu ovis miscella soak 5, then slow fire decocts 2h, filters while hot, obtains oil immersion thing;
3) mix: wait oil immersion thing temperature to be cooled to 50 DEG C and add step 1) dried cream powder of gained, stir, and polish 2 times with colloid mill, finally add Borneolum Syntheticum 5g, mix homogeneously, obtain sample 1.
2, sample 2:
The preparation method of Cortex Fraxini is become together with Folium Artemisiae Argyi, Flos Lonicerae, Cortex Phellodendri, Radix Scutellariae, Herba Houttuyniae, Gypsum Fibrosum powder by step 1 from oil immersion) described method makes dried cream powder, and other preparation processes are with the preparation method of sample 1.
Three, Therapeutic Method
Above 78 routine infant stochastic averagina are divided into 3 groups: matched group, treat 1 group and treatment 2 groups, wherein matched group adopts 999 baby Radix Arnebiae (Radix Lithospermi) eczema ointments (three nine-day periods after the winter solstice Pharmaceutical, 20140122), smears affected part every day 3 times; Treat 1 group and adopt sample 1, treat 2 groups and adopt sample 2, smear affected part equal every day 3 times.
Affected part is cleaned by the front warm water of medication, rubs affected part with the hands heat with hands, with cotton swab dip reference substance and sample 1, sample 2 is coated with and puts affected part on the skin, every day 3 times, within one week, is a course for the treatment of, two courses for the treatment of of treatment continuously, treatments period is stopped using other drug.
Four, criterion of therapeutical effect
1, cure: erythra, red pimple, erythema, little water scar, yellow squama and silly skin, ooze out, the clinical symptoms such as rotten to the corn all disappears, physical rehabilitation;
2, effective: clinical symptom relief, improvement;
3, invalid: to compare before symptom and treatment without improving.
Five, therapeutic outcome
In table 2, compare between group and check with ridit.
Duration of test matched group has 2 examples slightly bad, and 1 group, sample and 2 groups all do not observe untoward reaction.
Table 2, clinical effectiveness
| ? | Cure (n/%) | Effectively (n/%) | Invalid (n/%) | Total effective rate (%) | Untoward reaction rate |
| Matched group | 9(34.6) | 11(42.3) | 6(23.1) | 76.9 | 2(7.7％) |
| 1 group, sample | 19(73.1) | 6(23.1) | 1(3.8) | 96.2** | —— |
| 2 groups, sample | 17(65.4) | 7(26.9) | 2(7.7) | 92.3* | —— |
Note: compare * P < 0.05 with matched group; * P < 0.01.
Six, brief summary
Clinical effectiveness shows, contrast medicine, sample 1 and sample 2 all have good effect for infant eczema; Wherein Cortex Fraxini oil immersion (sample 1) is better than ethanol extraction (sample 2) effect, and contrasts medicine and compares and have pole significant difference (P < 0.01).
Following examples all can realize the effect of described experimental example.
Embodiment 1, a kind of pharmaceutical composition for the treatment of infant eczema, its raw material composition comprises the medical material of following weight portion: Radix Arnebiae (Radix Lithospermi) 80g, Folium Artemisiae Argyi 120g, Flos Lonicerae 70g, Cortex Fraxini 60g, Cortex Phellodendri 30g, Radix Scutellariae 25g, Herba Houttuyniae 15g, Gypsum Fibrosum 25g, Borneolum Syntheticum 5g.
The preparation method of aforementioned pharmaceutical compositions, comprises the steps:
1) dried cream powder is prepared: after Folium Artemisiae Argyi, Flos Lonicerae, Cortex Phellodendri, Radix Scutellariae, Herba Houttuyniae, Gypsum Fibrosum powder are broken into coarse powder, add the ethanol extraction 2 times of percent by volume 50%, the ethanol contend at every turn added is 7 times amount of medical material weight, each extraction 2h, extracting solution merges and filters and concentrate, dry, pulverize, and get dry extract powder 63.5g;
2) prepare oil immersion thing: Radix Arnebiae (Radix Lithospermi), Cortex Fraxini are ground into coarse powder, and add medical material 6 times of weight, Semen Lini oil that weight ratio is 2:1, refine Adeps Caprae seu ovis miscella soak 5, then slow fire decocts 2h, filters while hot, obtains oil immersion thing;
3) mix: wait oil immersion thing temperature to be cooled to 50 DEG C and add step 1) dried cream powder of gained, stir, and polish 2 times with colloid mill, finally add Borneolum Syntheticum, mix homogeneously, to obtain final product.
Embodiment 2, a kind of pharmaceutical composition for the treatment of infant eczema, its raw material composition comprises following medical material: Radix Arnebiae (Radix Lithospermi) 50g, Folium Artemisiae Argyi 100g, Flos Lonicerae 50g, Cortex Fraxini 50g, Cortex Phellodendri 20g, Radix Scutellariae 20g, Herba Houttuyniae 10g, Gypsum Fibrosum 20g, Borneolum Syntheticum 4g.
The preparation method of aforementioned pharmaceutical compositions, comprises the steps:
1) dried cream powder is prepared: after Folium Artemisiae Argyi, Flos Lonicerae, Cortex Phellodendri, Radix Scutellariae, Herba Houttuyniae, Gypsum Fibrosum powder are broken into coarse powder, add the ethanol extraction 2 times of percent by volume 35%, the ethanol contend at every turn added is 6 times amount of medical material weight, each extraction 1h, extracting solution merges and filters and concentrate, dry, pulverize, and get dry extract powder 54.5g;
2) prepare oil immersion thing: Radix Arnebiae (Radix Lithospermi), Cortex Fraxini are ground into coarse powder, and add medical material 3 times of weight, Semen Lini oil that weight ratio is 1:1, refine Adeps Caprae seu ovis miscella soak 3, then slow fire decocts 1h, filters while hot, obtains oil immersion thing;
3) mix: wait oil immersion thing temperature to be cooled to 50 DEG C and add step 1) dried cream powder of gained, stir, and polish 2 times with colloid mill, finally add Borneolum Syntheticum, mix homogeneously, to obtain final product.
Embodiment 3, a kind of pharmaceutical composition for the treatment of infant eczema, its raw material composition comprises following medical material: Radix Arnebiae (Radix Lithospermi) 100g, Folium Artemisiae Argyi 150g, Flos Lonicerae 100g, Cortex Fraxini 80g, Cortex Phellodendri 40g, Radix Scutellariae 40g, Herba Houttuyniae 20g, Gypsum Fibrosum 30g, Borneolum Syntheticum 10g.
The preparation method of aforementioned pharmaceutical compositions, comprises the steps:
1) dried cream powder is prepared: after Folium Artemisiae Argyi, Flos Lonicerae, Cortex Phellodendri, Radix Scutellariae, Herba Houttuyniae, Gypsum Fibrosum powder are broken into coarse powder, add the ethanol extraction 3 times of percent by volume 65%, the ethanol contend at every turn added is 10 times amount of medical material weight, each extraction 2h, extracting solution merges and filters and concentrate, dry, pulverize, and get dry extract powder 82.5g;
2) prepare oil immersion thing: Radix Arnebiae (Radix Lithospermi), Cortex Fraxini are ground into coarse powder, and add the Semen Lini oil of medical material 7 times of weight, refine Adeps Caprae seu ovis miscella (the two weight ratio 1:1) soaks 5, then slow fire decocts 2h, filters while hot, obtains oil immersion thing;
3) mix: wait oil immersion thing temperature to be cooled to 50 DEG C and add step 1) dried cream powder of gained, stir, and polish 2 times with colloid mill, finally add Borneolum Syntheticum, mix homogeneously, obtain pharmaceutical composition of the present invention.
Embodiment 4, a kind of pharmaceutical composition for the treatment of infant eczema, its raw material composition comprises following medical material: Radix Arnebiae (Radix Lithospermi) 80g, Folium Artemisiae Argyi 100g, Flos Lonicerae 50g, Cortex Fraxini 80g, Cortex Phellodendri 30g, Radix Scutellariae 30g, Herba Houttuyniae 20g, Gypsum Fibrosum 30g, Borneolum Syntheticum 6g.
The preparation method of aforementioned pharmaceutical compositions, comprises the steps:
1) dried cream powder is prepared: after Folium Artemisiae Argyi, Flos Lonicerae, Cortex Phellodendri, Radix Scutellariae, Herba Houttuyniae, Gypsum Fibrosum powder are broken into coarse powder, add the ethanol extraction 3 times of percent by volume 45%, the ethanol contend at every turn added is 6 times amount of medical material weight, each extraction 2h, extracting solution merges and filters and concentrate, dry, pulverize, and get dry extract powder 45.5g;
2) prepare oil immersion thing: Radix Arnebiae (Radix Lithospermi), Cortex Fraxini are ground into coarse powder, and add the Semen Lini oil of medical material 6 times of weight, refine Adeps Caprae seu ovis miscella (the two weight ratio 3:1) soaks 7, then slow fire decocts 1h, filters while hot, obtains oil immersion thing;
3) mix: wait oil immersion thing temperature to be cooled to 50 DEG C and add step 1) dried cream powder of gained, stir, and polish 2 times with colloid mill, finally add Borneolum Syntheticum, mix homogeneously, obtain pharmaceutical composition of the present invention.
Embodiment 5, a kind of pharmaceutical composition for the treatment of infant eczema, its raw material composition comprises following medical material: Radix Arnebiae (Radix Lithospermi) 80g, Folium Artemisiae Argyi 120g, Flos Lonicerae 70g, Cortex Fraxini 80g, Cortex Phellodendri 20g, Radix Scutellariae 20g, Herba Houttuyniae 10g, Gypsum Fibrosum 20g, Borneolum Syntheticum 5g.
The preparation method of aforementioned pharmaceutical compositions, comprises the steps
1) dried cream powder is prepared: after Cortex Fraxini, Folium Artemisiae Argyi, Flos Lonicerae, Cortex Phellodendri, Radix Scutellariae, Herba Houttuyniae, Gypsum Fibrosum powder are broken into coarse powder, add the ethanol extraction 2 times of percent by volume 50%, the ethanol contend at every turn added is 6 times amount of medical material weight, each extraction 1h, extracting solution merges and filters and concentrate, dry, pulverize, and get dry extract powder 63.5g;
2) prepare oil immersion thing: Radix Arnebiae (Radix Lithospermi) is ground into coarse powder, and add the Semen Lini oil of medical material 5 times of weight, refine Adeps Caprae seu ovis miscella (the two weight ratio 2:1) soaks 10, then slow fire decocts 1h, filters while hot, obtains oil immersion thing;
3) mix: wait oil immersion thing temperature to be cooled to 50 DEG C and add step 1) dried cream powder of gained, stir, and polish 2 times with colloid mill, finally add Borneolum Syntheticum, mix homogeneously, obtain pharmaceutical composition of the present invention.
Embodiment of the present invention only illustrates, is not restriction the present invention being made to other form, and the same change that any those skilled in the art utilize technology contents of the present invention to do, still belongs to the protection domain of technical solution of the present invention.
Claims (6)
1. treat the pharmaceutical composition of infant eczema for one kind, it is characterized in that, said composition is made up of the crude drug of following weight portion: Radix Arnebiae (Radix Lithospermi) 50-100 part, Folium Artemisiae Argyi 100-150 part, Flos Lonicerae 50-100 part, Cortex Fraxini 50-80 part, Cortex Phellodendri 20-40 part, Radix Scutellariae 20-40 part, Herba Houttuyniae 10-20 part, Gypsum Fibrosum 20-30 part, Borneolum Syntheticum 4-10 part.
2. the pharmaceutical composition for the treatment of infant eczema according to claim 1, it is characterized in that, said composition is made up of the crude drug of following weight portion: Radix Arnebiae (Radix Lithospermi) 80 parts, Folium Artemisiae Argyi 120 parts, Flos Lonicerae 70 parts, Cortex Fraxini 60 parts, Cortex Phellodendri 30 parts, Radix Scutellariae 25 parts, Herba Houttuyniae 15 parts, 25 parts, Gypsum Fibrosum, Borneolum Syntheticum 5 parts.
3. a preparation method for the pharmaceutical composition of the treatment infant eczema described in claim 1 or 2, step is as follows:
1) dried cream powder is prepared: after Folium Artemisiae Argyi, Flos Lonicerae, Cortex Phellodendri, Radix Scutellariae, Herba Houttuyniae, Gypsum Fibrosum powder are broken into coarse powder, add ethanol extraction 2-3 time of percent by volume 35-65%, the ethanol contend at every turn added is the 6-10 times amount of medical material weight, each extraction 1-2h, extracting solution merges and filters and concentrate, dry, pulverize, and get dry extract powder I;
Or: after Cortex Fraxini is ground into coarse powder together with Folium Artemisiae Argyi, Flos Lonicerae, Cortex Phellodendri, Radix Scutellariae, Herba Houttuyniae, Gypsum Fibrosum, obtain the dried cream powder II containing Cortex Fraxini by above-mentioned steps;
2) prepare oil immersion thing: Radix Arnebiae (Radix Lithospermi) is ground into coarse powder, and add Semen Lini oil, the refine Adeps Caprae seu ovis miscella immersion 3-10 day of medical material 3-7 times weight, then slow fire decocts 1-2h, filters while hot, obtains oil immersion thing I;
Or: by Cortex Fraxini together with Radix Arnebiae (Radix Lithospermi), obtain the oil immersion thing II containing Cortex Fraxini by above-mentioned steps;
3) mix: get step 2) the obtained oil immersion thing II containing Cortex Fraxini, temperature is cooled to 50 DEG C, adds step 1) obtained not containing the dried cream powder I of Cortex Fraxini, stir, and polish 2 times with colloid mill, finally add Borneolum Syntheticum, mix homogeneously, obtains pharmaceutical composition of the present invention;
Or: get step 2) obtained not containing oil immersion thing I and the step 1 of Cortex Fraxini) the obtained dried cream powder II containing Cortex Fraxini, obtain pharmaceutical composition of the present invention by above-mentioned steps;
The unit corresponding relation of the volume described in this method and weight is mL: g or L: kg.
4. the preparation method of the pharmaceutical composition for the treatment of infant eczema according to claim 3, it is characterized in that, step 1) described in the method preparing dried cream powder be: after described crude drug is ground into coarse powder, add the ethanol extraction 2 times of percent by volume 50%, the ethanol contend at every turn added is 7 times amount of medical material weight, each extraction 2h, extracting solution merges and filters and concentrate, dry, pulverize, and get dry extract powder I or II.
5. the preparation method of the pharmaceutical composition for the treatment of infant eczema according to claim 3, it is characterized in that, step 2) described in the method preparing oil immersion thing be: described crude drug is ground into coarse powder, and add the Semen Lini oil of medical material 6 times of weight, refine Adeps Caprae seu ovis miscella soaks 5, slow fire decocts 2h again, filter while hot, obtain oil immersion thing I or II.
6. the preparation method of the pharmaceutical composition of the treatment infant eczema according to any one of claim 3-5, is characterized in that, step 2) described in Semen Lini oil, refine Adeps Caprae seu ovis miscella weight ratio be 2: 1.
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| CN105343278A (en) * | 2015-12-15 | 2016-02-24 | 李国深 | Traditional Chinese medicine composition for infant itching dispelling |
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| CN101757387A (en) * | 2010-02-08 | 2010-06-30 | 张昌生 | Preparation method of traditional Chinese medicine for treating subcutaneous acute cellulitis |
| CN102895306A (en) * | 2012-11-16 | 2013-01-30 | 张旻 | All-natural herbal medicine lotion for infantile eczema |
| CN102973770A (en) * | 2012-11-13 | 2013-03-20 | 黄文珍 | Varicella-curing Chinese medicine combination and preparing method thereof |
| CN103055193A (en) * | 2012-12-03 | 2013-04-24 | 展继军 | Chinese medicinal composition for treating eczema |
| CN103784773A (en) * | 2012-10-30 | 2014-05-14 | 蔡田湉 | Health-care product for treating eczema |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101757387A (en) * | 2010-02-08 | 2010-06-30 | 张昌生 | Preparation method of traditional Chinese medicine for treating subcutaneous acute cellulitis |
| CN103784773A (en) * | 2012-10-30 | 2014-05-14 | 蔡田湉 | Health-care product for treating eczema |
| CN102973770A (en) * | 2012-11-13 | 2013-03-20 | 黄文珍 | Varicella-curing Chinese medicine combination and preparing method thereof |
| CN102895306A (en) * | 2012-11-16 | 2013-01-30 | 张旻 | All-natural herbal medicine lotion for infantile eczema |
| CN103055193A (en) * | 2012-12-03 | 2013-04-24 | 展继军 | Chinese medicinal composition for treating eczema |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105343278A (en) * | 2015-12-15 | 2016-02-24 | 李国深 | Traditional Chinese medicine composition for infant itching dispelling |
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