CN105381335B

CN105381335B - A kind of drug for treating eczema

Info

Publication number: CN105381335B
Application number: CN201510969217.8A
Authority: CN
Inventors: 毕新颖
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-12-21
Filing date: 2015-12-21
Publication date: 2018-12-28
Anticipated expiration: 2035-12-21
Also published as: CN105381335A

Abstract

The invention discloses a kind of drugs for treating eczema.It is made of oral preparation and traditional Chinese medicine lotion, and the oral preparation is made of following raw material medicaments: ginseng, Chinese yam, semen ziziphi spinosae, lily, dried orange peel, semen coicis, radix bupleuri, fingered citron, fructus lycii, cassia seed, Semen sesami nigrum, Radix Angelicae Sinensis, honeysuckle, dandelion, cape jasmine, rhizoma imperatae, rde bean and brown sugar；The traditional Chinese medicine lotion is made of following raw material medicaments: kuh-seng, cortex dictamni, the fruit of summer cypress and Chinese gall.Oral preparation of the invention all uses the material of dual-purpose of drug and food to be made, and is particularly suitable for youngsters and children and takes, and traditional Chinese medicine lotion prescription is simple, good effect.With drug therapy eczema of the invention, clinical effective rate 100%.

Description

A kind of drug for treating eczema

Technical field

The present invention relates to a kind of drugs for treating eczema, belong to pharmaceutical technology field.

Background technique

Eczema is a kind of common allergic skin disease easy to recur, is apt to occur in head, four limbs bend side and perineum etc. Position is often in general hair or symmetry distribution.Eczema is that a kind of scytitis of the acute pruritus as caused by a variety of internal and external factors is anti- It answers.Divide acute, subacute, chronic three phases.Acute stage tool exudation tendency, chronic phase, then infiltrate, are plump.Some patients directly show For chronic eczema.Skin lesion has the characteristics that pleomorphism, symmetry, itch and easy recurrent exerbation.No matter whenever, no matter body Which position suffered from dermatitis and eczema, all to patient can bring biggish pain because of because of violent itch, or even influence it Normal work, life, it is irritated and some other mental element barrier occur if to will lead to patient mental dispirited for long-term recurrence Hinder.Therefore active and effective treatment must be carried out to it.

For the treatment of eczema, it is divided into interior therapy and Topical therapy.The interior of eczema uses therapy based on hormone for oral administration, long Phase, which takes, can generate some toxin and side effect, and larger, easy recurrence is damaged to human body.Topical therapy are as follows: acute eczema is adopted more It is rinsed with local physiological salt water, 3% boric acid or 1:2000~1:10000 liquor potassic permanganate, soak, calamine lotion convergence, Protection；Subacute, chronic eczema is using suitable glucocorticoid creme, burnt oil-like formulations or immunomodulator, such as Ta Kemo Take charge of ointment, pimecrolimus ointment.Above-mentioned therapeutic modality is only capable of alleviating the symptom of eczema, cannot eradicate eczema.

Summary of the invention

The present invention overcomes above-mentioned the deficiencies in the prior art, provide a kind of drug for treating eczema.It is by oral preparation It being formed with traditional Chinese medicine lotion, oral preparation all uses the material of dual-purpose of drug and food to be made, is particularly suitable for youngsters and children and takes, in Medicine lotion prescription is simple, good effect.

The technical scheme is that a kind of drug for treating eczema, characterized in that by oral preparation and traditional Chinese medicine lotion group At,

The oral preparation is made of the bulk pharmaceutical chemicals of following weight parts: ginseng 10-15, Chinese yam 8-12, semen ziziphi spinosae 5-10, hundred Close 3-8, dried orange peel 10-15, semen coicis 8-12, radix bupleuri 15-20, fingered citron 10-15, fructus lycii 8-12, cassia seed 5-10, Semen sesami nigrum 3- 8, Radix Angelicae Sinensis 8-12, honeysuckle 10-15, dandelion 8-12, cape jasmine 8-12, rhizoma imperatae 5-10, rde bean 3-8, brown sugar 10-15；

The traditional Chinese medicine lotion is made of the bulk pharmaceutical chemicals of following weight parts: kuh-seng 15-20, cortex dictamni 8-12, fruit of summer cypress 8-12 With Chinese gall 5-10.

Preferably, the oral preparation is made of the bulk pharmaceutical chemicals of following weight parts: ginseng 12, Chinese yam 10, semen ziziphi spinosae 8, hundred Close 5, dried orange peel 12, semen coicis 10, radix bupleuri 18, fingered citron 12, fructus lycii 10, cassia seed 8, Semen sesami nigrum 5, Radix Angelicae Sinensis 10, honeysuckle 12, Pu Public English 10, cape jasmine 10, rhizoma imperatae 8, rde bean 5, brown sugar 12.

Preferably, the traditional Chinese medicine lotion is made of the bulk pharmaceutical chemicals of following weight parts: kuh-seng 18, cortex dictamni 10, the fruit of summer cypress 10 With Chinese gall 8.

Preparation and instructions of taking: each raw water of oral preparation is decocted, and after decoction liquor concentration, adds brown sugar, spraying It is spare that granule is obtained after drying, every bag of 3g；It takes 3 times a day.General adult dose is 2 bags every time, and children's dosage is every 0.5-1 bags secondary, baby's dosage within 1 years old is 1/3-1/2 bags.Each bulk pharmaceutical chemicals water of traditional Chinese medicine lotion is decocted, decoction liquor temperature is washed Affected part.Oral preparation and traditional Chinese medicine lotion are used in combination, and 3 days are 1 course for the treatment of.

Each raw material and effect:

Ginseng: sweet, slight bitter, tepor.Returns spleen, lung, the heart, kidney channel.Function and the major functions: replenish vital energy, restore pulse, and strengthen and remove vital energy, tonifying spleen benefit Lung, shengjin nourishing, tranquilize the mind and promote the intelligence.It to be taken off for physically weak, cold weak pulse of limb, spleen eating less, the deficiency syndrome of the lung is breathed with cough, injury thirst, and interior heat disappears Yearningly, deficiency of qi and blood, prolonged illness virtual winning, insomnia of palpitating with fear, impotence palace cold.

Chinese yam: sweet and neutral.Returns spleen, lung, kidney channel.Tonifying spleen nourishing the stomach, engender liquid and benefic lung, kidney tonifying arresting seminal emission.For spleen eating less, chronic diarrhea Incessantly, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, leukorrhagia, frequent micturition, and abnormal heat is quenched one's thirst.

Semen ziziphi spinosae: it is sweet, sour, it puts down.Return liver, gallbladder, the heart channel of Hang-Shaoyin.Function with the major functions: nourishing heart tonifying liver, antitoxic heart-soothing and sedative, arrest sweating promote the production of body fluid. For restlessness of asrhenia type and insomnia, horrified to much dream, body void hidrosis, injury thirst.

Lily: sweet in flavor, mild-natured, slight bitter；Return lung, the heart, kidney channel.With Yin nourishing and lung moistening, the effect of clearing away the heart fire and tranquillizing, cough-relieving.It is main Control yin chronic cough, blood-stained sputum, pharyngalgia aphonia；In the pyreticosis later period, waste heat is not clear or feelings will is unsuccessful, dysphoria palpitates with fear, insomnia and dreamful sleep, It is absent-minded, carbuncle swells.

Dried orange peel: bitter, acrid in flavour and warm in nature.Return lung, the spleen channel.Function with the major functions: regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm.For abdominal fullness and distention, food It is few to vomit and diarrhoea, coughing with a lot of sputum.

Semen coicis: it is sweet, light, it is cool.Returns spleen, stomach, lung channel.Function with the major functions: sharp water penetration is wet, arrange by invigorating the spleen to arrest diarrhea, eliminating impediment Purulence, detoxicating and resolving a mass.For oedema, tinea pedis, difficult urination, splenasthenic diarrhea, arthritis with fixed pain caused by dampness muscular constricture, pulmonary abscess, acute appendicitis；Wart, cancerous swelling.

Radix bupleuri: it is pungent, bitter, it is slightly cold.Return liver, gallbladder, lung channel.Function is brought down a fever with the major functions: evacuating, soothing liver-qi stagnation, lifting disease.With In cold, fever, fevers and chills alternate, distending pain in the chest and hypochondrium, irregular menstruation, uterine prolapse, rectal prolapse.

Fingered citron: pungent, bitter, sour, temperature.Return liver, spleen, lung channel.Function with the major functions: liver-smoothing, qi-regulating, protecting the stomach and relieve the pain.For liver stomach Qi It is stagnant, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, deficiency of food vomiting.

Fructus lycii: sweet and neutral.Return liver and kidney channel.Function with the major functions: nourishing liver and kidney, benefiting shrewd head.For consumption consumptive loss, waist and knee Ache, dizziness and tinnitus, impotence and seminal emission, Heat Diabetes, blood deficiency chlorosis, blurred vision.

Cassia seed: it is sweet in flavor, bitter, it is cold in nature, it is micro- salty.Return liver, large intestine channel.Effect: clearing liver and improving vision, relax bowel and defecation.

Semen sesami nigrum: sweet and neutral.Return liver, kidney, large intestine channel.Function with the major functions: nourishing liver and kidney, benefiting essence-blood, ease constipation are dry.For dizziness Dim eyesight, Hiccough and deaf, poliosis, post disease alopecia, dry constipation of intestines.

Radix Angelicae Sinensis: sweet, acrid, warm.Return liver, the heart, the spleen channel.Function with the major functions: replenishing and activating blood, regulating menstruation and relieving pain, moistening intestines and relaxing bowels.For Blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, amenorrhea and algomenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, intestinal dryness Constipation.Prepared RADIX ANGELICAE SINENSIS with yellow rice wine blood circulation.For amenorrhea and algomenorrhea, rheumatic arthralgia, injury from falling down.

Honeysuckle: it is sweet, it trembles with fear.Return lung, the heart, stomach meridian.Function with the major functions: clearing heat and detoxicating, dispelling wind and heat from the body.Sore is treated for carbuncle swells, Sore throat, erysipelas, toxic-heat and blood stasis, wind-heat cold, warm disease and fever.

Dandelion: it is bitter, sweet, it trembles with fear.Return liver, stomach meridian.Function with the major functions: clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia.For Furuncle swelling toxin, acute mastitis, scrofula, hot eyes, pharyngalgia, pulmonary abscess, acute appendicitis, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.

Cape jasmine: it is bitter, it trembles with fear.Return heart, lung, tri-jiao channel.Function with the major functions: purging intense heat relieving restlessness, clearing heat and promoting diuresis, removing pattogenic heat from the blood and toxic material from the body；External application Swelling and pain relieving.For Vexed, jaundice with damp-heat pathogen, the puckery pain of stranguria, blood-head tells nosebleed, red eye, swell pain, pathogenic fire,toxin and furuncles control bruise outside Bitterly.

Rhizoma imperatae: return lung, stomach, bladder meridian.Major function: cooling blood and hemostasis, reducing fever and causing diuresis.It spits blood for blood-head, bleeding from five sense organs or subcutaneous tissue, urine Blood, pyreticosis and polydipsia, jaundice, oedema, puckery pain of heat gonorrhea；Acute nephritis edema.

Rde bean: it is mild-natured, it is sweet in flavor, sour.Major function: inducing diuresis for removing edema, removing toxic substances apocenosis.For edema swelling, beriberi edema, Jaundice and reddish urine, beriberoid pyretic arthralgia, carbuncle sore tumefacting virus, abdominalgia with intestinal abscess.

Brown sugar: it is warm-natured, sweet in flavor, enter spleen, have the function of blood-enrich, invigorating the spleen warm stomach, it is slow in analgesic, activate blood circulation and disperse blood clots.

Kuh-seng: it is bitter, it trembles with fear.Return heart, liver, stomach, large intestine, bladder meridian.Function with the major functions: heat-clearing and damp-drying drug, desinsection, diuresis.For Hot dysentery, hematochezia, jaundice urodialysis, leukorrhea with reddish discharge, swelling of vulva pruritus vulvae, eczema, wet sore, pruitus, castor control trichomonas yin outside Road is scorching.

Cortex dictamni: it is bitter, it trembles with fear.Returns spleen, stomach, bladder meridian.Function and the major functions: heat-clearing and damp-drying drug, wind-dispelling removing toxic substances.For herpes simplex Poison, yellow water is dripping, eczema, rubeola, scabies sore leprosy, beriberoid pyretic arthralgia, jaundice and reddish urine.

The fruit of summer cypress: it is pungent, bitter, it trembles with fear.Return kidney, bladder meridian.Function with the major functions: clearing heat and promoting diuresis, dispelling wind and arresting itching.It is puckery for urine Bitterly, pruritus vulvae leukorrhagia, rubeola, eczema, pruitus.

Chinese gall: nature and flavor are sour, salty, cold, and acid can restrain, cold to detoxify, and have effects that sore fall fire, swollen for sore, tinea Poison, skin moisture fester are main ingredient in side.

Chinese medicine thinks: eczema patient and the puzzlement of heated and wet two kinds of disease and evils.On the one hand patient has excess fire, but because of body Function is dull, so that the chemical plant liver of human body fails to play the function of catharsis toxin expelling, intracorporal heat toxin is just arranged from size two It is external out.As a result have to transfer to be discharged from pore, if microcirculqtory system is not good enough or chosure of pores, toxin will gather in vivo. It is excluded to be unfavorable for the waste of body.Oral preparation 'Shugan Lidan ' of the invention, invigorating the spleen to dry, clearing heat and detoxicating, tranquilizing and allaying excitement, Enriching yin boost qi promoting blood circulation to make the heat toxin of body by liver transporting, and is excluded by stool and urine, while relax liver, invigorating the spleen, QI invigorating, peace Disease resistance of the mind to inhibit the generation again of heat toxin, and enhance body itself.Traditional Chinese medicine lotion heat-clearing and damp-drying drug, antipruritic, sore.Mouthful Formulation and traditional Chinese medicine lotion are used in combination, and can achieve the effect for the treatment of both manifestation and root cause of disease.

The beneficial effects of the present invention are: oral preparation of the invention all uses the material of dual-purpose of drug and food to be made, it is especially suitable It is taken for youngsters and children, traditional Chinese medicine lotion prescription is simple, good effect.With drug therapy eczema of the invention, clinical effective rate It is 100%.

Beneficial effects of the present invention are further illustrated below in conjunction with clinical data and typical case.

One, clinical observation

1, clinical data: carrying out clinical observation selected from January, 2014 to 100 eczema patients of in June, 2014 hospital outpatient, Wherein male 53, female 47.Age is between -65 years old 2 months.Wherein acute eczema 35, it is subacute eczema 21, chronic wet Rash 44.

2, diagnostic criteria:

2.1 acute eczema

(1) acute onset, skin lesion are made of erythema, papule, blister.Cluster slabbing often causes rotten to the corn, infiltration because scratching Out, it forms a scab and change, the blur margins such as suppuration is often symmetric.

(2) itching.

2.2 subacute eczemas: after acute lesion inflammation mitigates, sepage is reduced, protracted course, skin lesion with papule, the scales of skin that peel off and Based on incrustation, only a small number of papulo-vesicles and rotten to the corn or have mild infiltration.

2.3 chronic eczema

(1) can be caused since acute eczema recurrent exerbation or i.e. in chronic.

(2) be apt to occur in face, after ear, the positions such as Zhou, popliteal nest, shank, vulva and anus, with itching.

(3) skin lesion is relatively limited to, and plumpness infiltration is significant, and boundary understands, there is pigmentation more.

(4) course of disease is chronic, often there is acute attack.

3, treatment method

It is treated in such a way that the present invention takes orally and adds washout, 3 days are 1 course for the treatment of.

4, efficacy assessment standard:

Cure: skin lesion is all subsided, and gargalesthesia disappears；Follow-up half a year is without recurrence；

Effective: erythema, papule, papulo-vesicle 70% subside, and exudation disappears, and gargalesthesia is substantially reduced；

Improve: erythema, papule, papulo-vesicle 40% subside, and decrustation at incrustation, exudation significantly reduces, and gargalesthesia mitigates；

Invalid: fash is without significant change, and gargalesthesia is without mitigation.

5, treatment results

Cure 96, effective 3, effective 1, invalid 0.Total effective rate is 100%.

Two, typical case

Case 1, in so-and-so, female, 6 months.Before infant 15 days, there is small red pimple in face, gradually increases later, cheek, Forehead, glabella, head and the visible phlysis of upper limb, the yellow-white scales of skin that peel off and crust, occasionally there is sepage, are eczema through hospital diagnosis.Once It is smeared with traditional Chinese medicinal ointment, it is ineffective.Traditional Chinese medicine lotion washout affected part is combined using oral preparation (3 times a day, each 1g) of the invention Treatment, skin lesion is all subsided after 5 days, and gargalesthesia disappears；Follow-up half a year is without recurrence.

Case 2, Liang, male, 55 years old.Whole body breakout before patient 3 years, acute pruritus.Once it took orally prednisone and external application swashs Plain ointment, symptom mitigates when medication, recurs after drug withdrawal, unbearably, therapeutic effect is undesirable for itching.Through being taken orally using of the invention Preparation (3 times a day, each 6g) is treated in conjunction with traditional Chinese medicine lotion washout affected part, and skin lesion is all subsided after 9 days, and gargalesthesia disappears；Follow-up 1 Year is without recurrence.

Specific embodiment

Embodiment 1

Oral preparation matches (parts by weight) ginseng 12, Chinese yam 10, semen ziziphi spinosae 8, lily 5, dried orange peel 12, semen coicis 10, radix bupleuri 18, fingered citron 12, fructus lycii 10, cassia seed 8, Semen sesami nigrum 5, Radix Angelicae Sinensis 10, honeysuckle 12, dandelion 10, cape jasmine 10, rhizoma imperatae 8, red Red bean 5, brown sugar 12.

Traditional Chinese medicine lotion matches (parts by weight): kuh-seng 18, cortex dictamni 10, the fruit of summer cypress 10 and Chinese gall 8.

Embodiment 2

Oral preparation (parts by weight): ginseng 15, Chinese yam 12, semen ziziphi spinosae 10, lily 8, dried orange peel 15, semen coicis 12, radix bupleuri 20, It is fingered citron 15, fructus lycii 12, cassia seed 10, Semen sesami nigrum 8, Radix Angelicae Sinensis 12, honeysuckle 15, dandelion 12, cape jasmine 12, rhizoma imperatae 10, red Red bean 8, brown sugar 15；

Traditional Chinese medicine lotion (parts by weight): kuh-seng 20, cortex dictamni 12, the fruit of summer cypress 12 and Chinese gall 10.

Preparation and instructions of taking: with embodiment 1.

Embodiment 3

Oral preparation (parts by weight): ginseng 10, Chinese yam 8, semen ziziphi spinosae 5, lily 3, dried orange peel 10, semen coicis 8, radix bupleuri 15, Buddhist It is hand 10, fructus lycii 8, cassia seed 5, Semen sesami nigrum 3, Radix Angelicae Sinensis 8, honeysuckle 10, dandelion 8, cape jasmine 8, rhizoma imperatae 5, rde bean 3, red Sugar 10；

Traditional Chinese medicine lotion (parts by weight): kuh-seng 15, cortex dictamni 8, the fruit of summer cypress 8 and Chinese gall 5.

Preparation and instructions of taking: with embodiment 1.

Embodiment 4

Oral preparation (parts by weight): ginseng 15, Chinese yam 10, semen ziziphi spinosae 7, lily 5, dried orange peel 10, semen coicis 8, radix bupleuri 15, Buddhist Hand 12, fructus lycii 10, cassia seed 5, Semen sesami nigrum 3, Radix Angelicae Sinensis 10, honeysuckle 12, dandelion 10, cape jasmine 8, rhizoma imperatae 5, rde bean 3, Brown sugar 10；

Traditional Chinese medicine lotion (parts by weight): kuh-seng 15, cortex dictamni 10, the fruit of summer cypress 10 and Chinese gall 5.

Preparation and instructions of taking: with embodiment 1.

Claims

1. a kind of drug for treating eczema, characterized in that it is made of oral preparation and traditional Chinese medicine lotion,

The oral preparation is made of the bulk pharmaceutical chemicals of following weight parts: ginseng 10-15, Chinese yam 8-12, semen ziziphi spinosae 5-10, lily 3- 8, dried orange peel 10-15, semen coicis 8-12, radix bupleuri 15-20, fingered citron 10-15, fructus lycii 8-12, cassia seed 5-10, Semen sesami nigrum 3-8, when Return 8-12, honeysuckle 10-15, dandelion 8-12, cape jasmine 8-12, rhizoma imperatae 5-10, rde bean 3-8, brown sugar 10-15；

The traditional Chinese medicine lotion is made of the bulk pharmaceutical chemicals of following weight parts: kuh-seng 15-20, cortex dictamni 8-12, fruit of summer cypress 8-12 and five Gall nut 5-10.

2. a kind of drug for treating eczema as described in claim 1, characterized in that the oral preparation is by following weight parts Bulk pharmaceutical chemicals are made: ginseng 12, Chinese yam 10, semen ziziphi spinosae 8, lily 5, dried orange peel 12, semen coicis 10, radix bupleuri 18, fingered citron 12, fructus lycii 10, cassia seed 8, Semen sesami nigrum 5, Radix Angelicae Sinensis 10, honeysuckle 12, dandelion 10, cape jasmine 10, rhizoma imperatae 8, rde bean 5, brown sugar 12.

3. a kind of drug for treating eczema as claimed in claim 1 or 2, characterized in that the traditional Chinese medicine lotion is by following weight The bulk pharmaceutical chemicals of part are made: kuh-seng 18, cortex dictamni 10, the fruit of summer cypress 10 and Chinese gall 8.