CN107929598A - A kind of Chinese medicine composition for treating gout and preparation method thereof - Google Patents
A kind of Chinese medicine composition for treating gout and preparation method thereof Download PDFInfo
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- CN107929598A CN107929598A CN201711261787.7A CN201711261787A CN107929598A CN 107929598 A CN107929598 A CN 107929598A CN 201711261787 A CN201711261787 A CN 201711261787A CN 107929598 A CN107929598 A CN 107929598A
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Abstract
The invention belongs to technical field of traditional Chinese medicines, a kind of Chinese medicine composition for treating gout, in parts by weight, which is made of the raw material of following parts by weight:10~20 parts of Rhizoma Atractylodis Macrocephalae,10~15 parts of Poria cocos,10~20 parts of coix seed,10~15 parts of rhizoma atractylodis,15~30 parts of gypsum,10~15 parts of cassia twig,10~20 parts of rhizoma anemarrhenae,10~15 parts of the root bark of tree peony,10~15 parts of Cortex Phellodendri,10~30 parts of Radix Salviae Miltiorrhizae,15~20 parts of reticulate millettia,10~15 parts of pangolin,Damp 10~20 parts of sunset,Centipede 2,15~20 parts of zaocys dhumnade,10~15 parts of rhizoma cyperi,10~20 parts of corydalis tuber,10~15 parts of the banksia rose,6~9 parts of Semen Strychni (processed),The present invention is using Rhizoma Atractylodis Macrocephalae as monarch drug in a prescription,Using Poria cocos and coix seed as ministerial drug,With rhizoma atractylodis,Gypsum,Cassia twig,Rhizoma anemarrhenae,The root bark of tree peony,Cortex Phellodendri,Radix Salviae Miltiorrhizae,Reticulate millettia,Pangolin,Damp sunset,Centipede,Zaocys dhumnade,Rhizoma cyperi,Corydalis tuber,The banksia rose is adjutant,Using Semen Strychni (processed) to make medicine,Compatibility is reasonable,Complement each other,For ventilation,Have no toxic side effect,Good effect,Short treating period,Treat both principal and secondary aspect of disease,Do not recur.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine composition for treating gout and preparation method thereof.
Background technology
Gout (gout) is one group of heterogeneity chronic metabolic disease caused by disorders of purine metabolism, its clinical characters is height
Uricacidemia, gouty acute arthritis, interstitial nephritis and the tophus of recurrent exerbation are formed;Severe patient with joint deformity or
Uric acid lithangiuria.This disease is often accompanied by obesity, diabetes B, hyperlipidemia, hypertension, artery sclerosis and coronary heart disease etc., faces
It is known as metabolic syndrome on bed.Hyperuricemia and gout are only one of performance in this syndrome.Gout can according to cause of disease difference
It is divided into two major class of primary and Secondary cases.Primary gout refers on the basis of other diseases are excluded, due to congenital purine generation
Thank caused by disorderly and (or) uric acid excretion disorder;Secondary gout refers to be arranged secondary to uric acid caused by kidney trouble or some drugs
Let out reduction, myeloproliferative disease and the generation of uric acid caused by chemotherapy of tumors increases.Primary gout:There is heredity more, but face
Bed has gout family history person only to account for 10%~20%.Uric acid generation excessively accounts for 10% in the cause of disease of primary hyperuricemia.
Its reason is mainly purine metabolism enzyme defect, and hypoxanthine guanine phosphoribosyltransferase (HGPRT) lacks and ribose phosphate
Pyrophosphate (PRPP) synthase activity is hyperfunction.Primary renal underexcretion accounts for primary hyperuricemia
90%, specific pathogenesis is unclear, may be multiple-factor inheritance disease, but should exclude kidney organic disease.Secondary cases pain
Wind:Refer to secondary to a kind of clinical manifestation during other diseases, also can be caused by some drugs.Myeloproliferative disease is for example white
Blood disease, lymthoma, Huppert's disease, polycythemia, hemolytic anemia and cancer etc. can cause the propagation of cell to accelerate,
Make nucleic acid conversion increase, cause uric acid to produce and increase.Malignant tumour causes cell considerable damage, nucleic acid after the chemicotherapy of tumour
Conversion also increases, and causes uric acid to produce and increases.Kidney trouble includes chronic glomerulonephritis, pyelonephritis, polycystic kindey, lead poisoning
With hypertension late period etc. caused by detection of glomeruli filtration function decline, underexcretion can be made, cause serum Uric Acid Concentration to raise.Medicine
Thing such as thiazide diuretic, frusemide, ethambutol, pyrazinamide, low-dosage aspirin and nicotinic acid etc., contestable suppress
Tubular excretion uric acid and cause hyperuricemia.In addition, high urine can also occur for renal transplant recipients long-term use immunodepressant
Acidaemia, it is related may to suppress tubular excretion uric acid with immunodepressant.At present, primary gout lacks etiological treatment, still
Without radical cure method.
The content of the invention
To solve the above problems, the technical solution adopted by the present invention is:
A kind of Chinese medicine composition for treating gout, in parts by weight, the Chinese medicine composition by following parts by weight raw material group
Into:10~20 parts of Rhizoma Atractylodis Macrocephalae, 10~15 parts of Poria cocos, 10~20 parts of coix seed, 10~15 parts of rhizoma atractylodis, 15~30 parts of gypsum, cassia twig 10
~15 parts, 10~20 parts of rhizoma anemarrhenae, 10~15 parts of the root bark of tree peony, 10~15 parts of Cortex Phellodendri, 10~30 parts of Radix Salviae Miltiorrhizae, 15~20 parts of reticulate millettia, wear
10~15 parts of naze, damp 10~20 parts of sunset, centipede 2,15~20 parts of zaocys dhumnade, 10~15 parts of rhizoma cyperi, 10~20 parts of corydalis tuber, wood
Fragrant 10~15 parts, 6~9 parts of Semen Strychni (processed).
The Chinese medicine composition of above-mentioned treatment gout, preferred ingredient are:15~18 parts of Rhizoma Atractylodis Macrocephalae, 11~13 parts of Poria cocos, coix seed
13~18 parts, it is 12~13 parts of rhizoma atractylodis, 18~25 parts of gypsum, 11~14 parts of cassia twig, 13~18 parts of rhizoma anemarrhenae, 12~15 parts of the root bark of tree peony, yellow
12~15 parts of cypress, 18~26 parts of Radix Salviae Miltiorrhizae, 17~19 parts of reticulate millettia, 12~15 parts of pangolin, damp 10~18 parts of sunset, centipede 2, crow
16~20 parts of tip snake, 13~15 parts of rhizoma cyperi, 15~20 parts of corydalis tuber, 10~15 parts of the banksia rose, 6~9 parts of Semen Strychni (processed).
The Chinese medicine composition of above-mentioned treatment gout, optimal component are:16 parts of Rhizoma Atractylodis Macrocephalae, 12 parts of Poria cocos, 15 parts of coix seed, rhizoma atractylodis
12 parts, 20 parts of gypsum, 12 parts of cassia twig, 15 parts of rhizoma anemarrhenae, 13 parts of the root bark of tree peony, 13 parts of Cortex Phellodendri, 20 parts of Radix Salviae Miltiorrhizae, 17 parts of reticulate millettia, pangolin
13 parts, damp 13 parts of sunset, centipede 2,18 parts of zaocys dhumnade, 14 parts of rhizoma cyperi, 17 parts of corydalis tuber, 13 parts of the banksia rose, 7 parts of Semen Strychni (processed);It is or, white
17 parts of art, 13 parts of Poria cocos, 16 parts of coix seed, 13 parts of rhizoma atractylodis, 23 parts of gypsum, 13 parts of cassia twig, 17 parts of rhizoma anemarrhenae, 14 parts of the root bark of tree peony, Cortex Phellodendri
14 parts, 24 parts of Radix Salviae Miltiorrhizae, 18 parts of reticulate millettia, 14 parts of pangolin, damp 16 parts of sunset, centipede 2,19 parts of zaocys dhumnade, 15 parts of rhizoma cyperi, corydalis tuber
18 parts, 15 parts of the banksia rose, 8 parts of Semen Strychni (processed).
The Chinese medicine composition of above-mentioned treatment gout, the Chinese medicine composition can be made any in pulvis, capsule and decoction
It is a kind of.
The invention also discloses a kind of preparation method of the Chinese medicine composition of the treatment gout, formulation is capsule, bag
Include following steps:
Step (1):According to it is described treatment gout Chinese medicine composition parts by weight of raw materials weigh Rhizoma Atractylodis Macrocephalae, Poria cocos, coix seed,
Rhizoma atractylodis, gypsum, cassia twig, rhizoma anemarrhenae, the root bark of tree peony, Cortex Phellodendri, Radix Salviae Miltiorrhizae, reticulate millettia, pangolin, damp sunset, centipede, zaocys dhumnade, rhizoma cyperi, corydalis tuber,
The banksia rose, Semen Strychni (processed);
Step (2):The Chinese medicine material weighed in step (1) is placed in clear water and soaks 10-15min, is removed miscellaneous in medicinal powder
Thing;
Step (3):Chinese medicine material obtained by step (2) is pulled out from water, is placed under natural light and dries;Dry rear aqueous
Rate is controlled less than or equal to 98%;
Step (4):Step (3) dried Chinese medicine is placed in grinding machine for Chinese herb medicines and is pulverized, crosses 500-800 mesh sieves point
Afterwards, when sterilization processing 12-24 is small under UV light sterilization lamp;
Step (5):The herb powder that step (4) obtains is filled in capsule, that is, the Chinese medicinal capsule for the gout that obtains medical treatment.
The invention also discloses the preparation method of the Chinese medicine composition of second for the treatment of gout, formulation is pulvis, including such as
Lower step:
Step (1):According to it is described treatment gout Chinese medicine composition parts by weight of raw materials weigh Rhizoma Atractylodis Macrocephalae, Poria cocos, coix seed,
Rhizoma atractylodis, gypsum, cassia twig, rhizoma anemarrhenae, the root bark of tree peony, Cortex Phellodendri, Radix Salviae Miltiorrhizae, reticulate millettia, pangolin, damp sunset, centipede, zaocys dhumnade, rhizoma cyperi, corydalis tuber,
The banksia rose, Semen Strychni (processed);
Step (2):The Chinese medicine material weighed in step (1) is placed in clear water and soaks 10-15min, is removed miscellaneous in medicinal powder
Thing;
Step (3):Chinese medicine material obtained by step (2) is pulled out from water, is placed under natural light and dries;Dry rear aqueous
Rate is controlled less than or equal to 98%;
Step (4):Step (3) dried Chinese medicine is placed in grinding machine for Chinese herb medicines and is pulverized, crosses 500-800 mesh sieves point
Afterwards, when sterilization processing 12-24 is small under UV light sterilization lamp;
Step (5):The herb powder that step (4) obtains is fitted into Chinese medicine net bag, that is, the traditional Chinese medicine powder for the gout that obtains medical treatment
Agent.
The invention also discloses the preparation method of the Chinese medicine composition of the third treatment gout, formulation is decoction, including such as
Lower step:
Step (1):According to it is described treatment gout Chinese medicine composition parts by weight of raw materials weigh Rhizoma Atractylodis Macrocephalae, Poria cocos, coix seed,
Rhizoma atractylodis, gypsum, cassia twig, rhizoma anemarrhenae, the root bark of tree peony, Cortex Phellodendri, Radix Salviae Miltiorrhizae, reticulate millettia, pangolin, damp sunset, centipede, zaocys dhumnade, rhizoma cyperi, corydalis tuber,
The banksia rose, Semen Strychni (processed);
Step (2):The Chinese medicine material weighed in step (1) is placed in medicine pot, and adds clear water immersion 30min, is removed
Debris in medicinal powder;The addition of clear water is advisable with flooding all Chinese medicine materials, after immersion, after boiling by intense fire, and slow boiling heating
30-50 minutes, filter to obtain a liquid;
Step (3):Add clear water in the dregs of a decoction into step (2) in marmite, the addition of clear water is to flood all dregs of a decoction
It is advisable, carries out second and decoct, first boil by intense fire, then be cooked by slow fire 30 minutes, filters to obtain secondary liquid;
Step (4):Gained liquid in step (2) and step (3) is merged, pack, cooled to room temperature is placed on ice
Refrigerated in case, refrigerated storage temperature is controlled at 0-5 DEG C, and the traditional Chinese herbal decoction for the treatment of gout is thus made.
Each component pharmacology is as follows:
Rhizoma Atractylodis Macrocephalae:Meridian distribution of property and flavor:Bitter, it is sweet, it is warm-natured.Returns spleen, stomach.Major function:Strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis,
Tocolysis.For spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, fetal irritability.Rhizoma Atractylodis Macrocephalae invigorating the spleen, and stomach, tocolysis.
For spleen eating less, diarrhea loose stool, fetal irritability.
Poria cocos:Nature and flavor:It is sweet light, put down.Channel tropism:Liver Channel, stomach, the spleen channel.Clearing damp and promoting diuresis, invigorating the spleen calming heart.For oedema oliguria,
Phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.
Coix seed:Nature and flavor:It is sweet light, it is cool.Enter spleen, lung, kidney channel.Invigorating the spleen excreting dampness, remove numbness antidiarrheal, heat-clearing row are dense.For oedema,
Tinea pedis, difficult urination, arthritis with fixed pain caused by dampness contraction, splenasthenic diarrhea, lung carbuncle, acute appendicitis;Flat wart.
Rhizoma atractylodis:Nature and flavor:It is arduous, temperature.Channel tropism:Enter spleen, stomach.It is drying damp and strengthening spleen, expelling wind and clearing away cold, improving eyesight.For abdominal fullness and distention,
Diarrhea oedema, tinea pedis Wei lame, arthralgia pain due to rheumatism, anemofrigid cold, yctalopia.
Gypsum:Nature and flavor:Xin Gan, trembles with fear.Enter stomach, lung channel.Control pyreticosis high fever not move back, vexed coma, delirious speech is gone mad, thirsty pharynx
Dry, lung heat asthma is anxious, heatstroke spontaneous perspiration, stomach fire headache, toothache, and heat toxin, which is stopped up, contains, spot dermexanthesis, aphthae.Forge deposited myogenic sore.Outside
Ulcer sores are controlled, bursts and does not close up, the burning hot wound of soup.
Cassia twig:Nature and flavor:Pungent sweet, warm.Enter bladder, the heart, lung channel.Sweating expelling pathogenic factors from muscles and skin, warming meridian, helps yang transforming qi, flat gas that spins.
For anemofrigid cold, coldness and pain in the epigastrium, blood trembles with fear Amenorrhea, joint pain, phlegm and retained fluid, oedema, palpitaition, run quickly globefish.
Rhizoma anemarrhenae:Nature and flavor:Hardship, trembles with fear.Enter lung, stomach, kidney channel.Clearing heat-fire, fluid dryness.For fever caused by exogenous pathogenic factors, hyperpyrexia polydipsia,
Lung-heat type cough, osteopyrexia and fever, Heat Diabetes, dry constipation of intestines.
The root bark of tree peony:Nature and flavor:Bitter, acrid, cold.Channel tropism:Enter the heart, liver and kidney channel.Function:Clearing heat and cooling blood, promoting blood circulation to remove blood stasis.Cure mainly:Macula
Hematemesis, amenorrhea due to stagnation of blood, premenstrual fever, carbuncle sore tumefacting virus, traumatic blood stasis, fever due to yin deficiency, lossless sliding steaming.
Cortex Phellodendri:Meridian distribution of property and flavor:Bitter, it is cold in nature.Kidney, bladder warp.Function:There is a heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment
Effect.Cure mainly:For damp-heat dysentery, jaundice, with lower pruritus vulvae, puckery pain of heat gonorrhea, tinea pedis impotence is knitted, and hectic fever due to yin labor heat, night sweat, loses
Essence, sore swollen toxin, eczema wet sore.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing yin and lessening fire.For fire excess from yin deficiency, night sweat hectic fever due to yin.
Radix Salviae Miltiorrhizae:Nature and flavor:Bitter, is slightly cold.Channel tropism:Converge to heart and liver channels.Effect:Promoting blood circulation, inducing meastruation to relieve menalgia, relieving restlessness that clears away heart-fire are cool
Blood disappears carbuncle.For chest impediment and cardialgia, gastral cavity abdomen hypochondriac pain, the accumulation of lump in the abdomen lump in the abdomen, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhoea Amenorrhea, sore
Ulcer swells and ache.
Reticulate millettia:Meridian distribution of property and flavor:Bitter;Micro-sweet;It is warm-natured.The heart channel of Hang-Shaoyin;The spleen channel.Function:Enrich blood, invigorate blood circulation, dredging collateral.For menstruation
It is uncomfortable, blood deficiency chlorosis, paralysis and numbness, arthralgia pain due to rheumatism.Cure mainly:Activate blood and relax tendons;Nourishing blood for regulating menstruation.Master is numb in every limb;Quadriplegia;Wind
Arthritis with fixed pain caused by dampness pain;Women has through uncomfortable;Dysmenorrhoea;Amenorrhoea.
Pangolin:Nature and flavor:It is salty, it is cool.Channel tropism:Enter Liver Channel, stomach.Major function:Enriching yin, enriches blood.It is few to control deficiency of Yin blood, waist and knee
Impotence is weak, Cough osteopyrexia, and seminal emission, uterine bleeding, irregular menstruation, quenches one's thirst, number of urinating, deaf, blurred vision.
Damp sunset:Damp sunset refers to raw rhizoma alismatis.It is raw with the person of being used as medicine for the section of active compound decontamination.Main function is removing toxic substances, sweet in flavor;It is light;
It is cold in nature.Return kidney;Bladder warp.Li Shui, excreting dampness, expels the heat-evil.Difficult urination is controlled, oedema turgor, vomits, rush down dysentery, phlegm and retained fluid, tinea pedis, gonorrhoea,
Hematuria.
Centipede:Nature and flavor:It is acrid in flavour and warm in nature.Return liver warp.Effect:Antispastic cramp and relieves dizziness, removes obstruction in channels to relieve pain, dispersing pathogen accumulation.Cure mainly:For liver wind
It is interior dynamic, spasm twitch, child convulsion, apoplexy, hemiplegia, lockjaw, rheumatoid arthritis stubborn, migraine and general headache, sore, snakebite and bugbite.
Zaocys dhumnade:Nature and flavor:It is sweet in flavor, it is mild-natured.Effect:Dispelling wind and removing obstruction in the meridians, arresting convulsion.Cure mainly arthralgia pain due to rheumatism, frightened epilepsy, skin mange,
Face sore, leprosy.
Rhizoma cyperi:Meridian distribution of property and flavor:Pungent, slight bitter, micro- sweet and neutral.Return liver, spleen, tri-jiao channel.Regulating the flow of vital energy Xie Yu, relieves pain menstruation regulating.Control liver stomach
Discord, depression of QI, the chest and abdomen distending pain in hypochondrium, phlegm and retained fluid feeling of fullness, irregular menstruation, under uterine bleeding band.
Corydalis tuber:Meridian distribution of property and flavor:It is pungent, bitter, temperature.Return liver, the spleen channel.It is promoting blood circulation and removing blood stasis, promoting qi circulation and relieving pain quality goods, especially to relieve pain it
Effect and be world-famous for.Li Shizhen (1518-1593 A.D.) exists《Compendium of Materia Medica》Middle conclusion corydalis tuber has " promoting blood circulation, qi-regulating, analgesic, diuresis " four large effects,
And praise highly corydalis tuber " can the stagnation of the circulation of vital energy in promoting circulation of blood, stasis in gas, therefore specially control all pains up and down all over the body ".
The banksia rose:Nature and flavor:Pungent acrid flavour;It is bitter;It is warm-natured.Channel tropism:Returns spleen;Large intestine, tri-jiao channel.Effect:Promoting the circulation of qi, analgesic, invigorating the spleen, disappears
Food.Cure mainly:Promoting qi circulation and relieving pain;Led in tune stagnant.Main born of the same parents coerce turgor foot;Abdominal distention;Spit diarrhea;Weight after dysentery.It is swollen for chest gastral cavity
Bitterly, weight after rush down dysentery, dyspepsia, do not feel like eating;Middle gas does not save;Sudden deafness;Snakebite and bugbite;Toothache.
Semen Strychni (processed):Vomiting nut bitter, warm-natured, very toxic, Return liver, the spleen channel, have and remove obstruction in channels to relieve pain, the work(of mass dissipating and swelling eliminating
Effect.Semen Strychni (processed) toxicity reduces, and quality is crisp, also easily crushes, and for taking orally, ball is often made and dissipates application.It is chiefly used in arthralgia pain due to rheumatism,
Traumatic injury, stasis caused pain of fracturing, skin sore, scrofula, subcutaneous nodule, paralysis and numbness.Effect:It is promoting blood circulation and removing obstruction in channels;Vomiting nut has relaxing tendons and activating collaterals,
The effect of cold dispelling dredging collateral.For breast lump, ulcer sore pain has the effect of fine.Antiphlogistic antibacterial:Vomiting nut also has anti-inflammatory effect,
There is the effect of certain suitable for nonspecific inflammation ulcer sore pain.Analgesic:Vomiting nut is that Chinese medicine relieves pain one of most effective medicine,
Particularly newborn pain treating rheumatic ostealgia, muscular injury pain have special efficacy.Expelling the stasis for the new:Vomiting nut is to polio, numb in every limb, anticancer
Deng also having certain effect.
The present invention is using the Rhizoma Atractylodis Macrocephalae of strengthening the spleen and replenishing qi as monarch drug in a prescription, using the Poria cocos of clearing damp and promoting diuresis and the coix seed of invigorating the spleen excreting dampness as minister
Medicine, with drying damp and strengthening spleen rhizoma atractylodis, the gypsum for controlling pyreticosis, the cassia twig of warming meridian, the rhizoma anemarrhenae of clearing heat-fire, clearing heat and cooling blood pellet
Skin, the Cortex Phellodendri of purging intense heat, except steaming, the Radix Salviae Miltiorrhizae of promoting blood circulation, reticulate millettia promoting blood circulation and removing obstruction in channels, the pangolin of nourishing yin and supplementing blood, clearing damp and promoting diuresis
Damp sunset, the centipede removed obstruction in channels to relieve pain, the zaocys dhumnade of dispelling wind and removing obstruction in the meridians, the rhizoma cyperi of regulating the flow of vital energy Xie Yu, corydalis tuber promoting blood circulation and removing blood stasis, promoting qi circulation and relieving pain
The banksia rose is adjutant, to remove obstruction in channels to relieve pain, the Semen Strychni (processed) of mass dissipating and swelling eliminating as medicine is made, compatibility is reasonable, complements each other, give full play to each
Pharmacological property, there is the effect of clearing heat-fire, invigorating the spleen excreting dampness, nourishing yin and supplementing blood, promoting blood circulation and removing obstruction in channels, inducing meastruation to relieve menalgia, for ventilation, nontoxic pair
Effect, good effect, short treating period, treats both principal and secondary aspect of disease, and does not recur.
The Chinese medicine composition can be prepared into the diversified forms such as Chinese medicinal tablet, particle, traditional Chinese medicine pill, be not limited to decoction and
Capsule, suitable for a variety of therapeutic modalities, application method.
Embodiment
The present invention is further described with reference to embodiment.
Embodiment 1
A kind of Chinese medicine composition for treating gout, in parts by weight, the Chinese medicine composition by following parts by weight raw material group
Into:10 parts of Rhizoma Atractylodis Macrocephalae, 15 parts of Poria cocos, 10 parts of coix seed, 15 parts of rhizoma atractylodis, 15 parts of gypsum, 15 parts of cassia twig, 10 parts of rhizoma anemarrhenae, 15 parts of the root bark of tree peony,
10 parts of Cortex Phellodendri, 30 parts of Radix Salviae Miltiorrhizae, 15 parts of reticulate millettia, 15 parts of pangolin, damp 10 parts of sunset, centipede 2,20 parts of zaocys dhumnade, 10 parts of rhizoma cyperi,
20 parts of corydalis tuber, 10 parts of the banksia rose, 9 parts of Semen Strychni (processed).
Embodiment 2
A kind of Chinese medicine composition for treating gout, in parts by weight, the Chinese medicine composition by following parts by weight raw material group
Into:20 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of Poria cocos, 20 parts of coix seed, 10 parts of rhizoma atractylodis, 30 parts of gypsum, 10 parts of cassia twig, 20 parts of rhizoma anemarrhenae, 10 parts of the root bark of tree peony,
15 parts of Cortex Phellodendri, 10 parts of Radix Salviae Miltiorrhizae, 20 parts of reticulate millettia, 10 parts of pangolin, damp 20 parts of sunset, centipede 2,15 parts of zaocys dhumnade, 15 parts of rhizoma cyperi,
10 parts of corydalis tuber, 15 parts of the banksia rose, 6 parts of Semen Strychni (processed).
Embodiment 3
A kind of Chinese medicine composition for treating gout, in parts by weight, the Chinese medicine composition by following parts by weight raw material group
Into:15 parts of Rhizoma Atractylodis Macrocephalae, 13 parts of Poria cocos, 13 parts of coix seed, 13 parts of rhizoma atractylodis, 18 parts of gypsum, 14 parts of cassia twig, 13 parts of rhizoma anemarrhenae, 15 parts of the root bark of tree peony,
12 parts of Cortex Phellodendri, 26 parts of Radix Salviae Miltiorrhizae, 17 parts of reticulate millettia, 15 parts of pangolin, damp 10 parts of sunset, centipede 2,16 parts of zaocys dhumnade, 15 parts of rhizoma cyperi,
15 parts of corydalis tuber, 15 parts of the banksia rose, 6 parts of Semen Strychni (processed).
Embodiment 4
A kind of Chinese medicine composition for treating gout, in parts by weight, the Chinese medicine composition by following parts by weight raw material group
Into:18 parts of Rhizoma Atractylodis Macrocephalae, 11 parts of Poria cocos, 18 parts of coix seed, 12 parts of rhizoma atractylodis, 25 parts of gypsum, 11 parts of cassia twig, 18 parts of rhizoma anemarrhenae, 12 parts of the root bark of tree peony,
15 parts of Cortex Phellodendri, 18 parts of Radix Salviae Miltiorrhizae, 19 parts of reticulate millettia, 12 parts of pangolin, damp 18 parts of sunset, centipede 2,20 parts of zaocys dhumnade, 13 parts of rhizoma cyperi,
20 parts of corydalis tuber, 10 parts of the banksia rose, 9 parts of Semen Strychni (processed).
Embodiment 5
A kind of Chinese medicine composition for treating gout, in parts by weight, the Chinese medicine composition by following parts by weight raw material group
Into:16 parts of Rhizoma Atractylodis Macrocephalae, 12 parts of Poria cocos, 15 parts of coix seed, 12 parts of rhizoma atractylodis, 20 parts of gypsum, 12 parts of cassia twig, 15 parts of rhizoma anemarrhenae, 13 parts of the root bark of tree peony,
13 parts of Cortex Phellodendri, 20 parts of Radix Salviae Miltiorrhizae, 17 parts of reticulate millettia, 13 parts of pangolin, damp 13 parts of sunset, centipede 2,18 parts of zaocys dhumnade, 14 parts of rhizoma cyperi,
17 parts of corydalis tuber, 13 parts of the banksia rose, 7 parts of Semen Strychni (processed).
Embodiment 6
A kind of Chinese medicine composition for treating gout, in parts by weight, the Chinese medicine composition by following parts by weight raw material group
Into:17 parts of Rhizoma Atractylodis Macrocephalae, 13 parts of Poria cocos, 16 parts of coix seed, 13 parts of rhizoma atractylodis, 23 parts of gypsum, 13 parts of cassia twig, 17 parts of rhizoma anemarrhenae, 14 parts of the root bark of tree peony,
14 parts of Cortex Phellodendri, 24 parts of Radix Salviae Miltiorrhizae, 18 parts of reticulate millettia, 14 parts of pangolin, damp 16 parts of sunset, centipede 2,19 parts of zaocys dhumnade, 15 parts of rhizoma cyperi,
18 parts of corydalis tuber, 15 parts of the banksia rose, 8 parts of Semen Strychni (processed).
Embodiment 7:Capsule is made
The preparation method of the Chinese medicine composition for the treatment of gout described in embodiment 1-6, formulation are capsule, including following step
Suddenly:
Step (1):According to it is described treatment gout Chinese medicine composition parts by weight of raw materials weigh Rhizoma Atractylodis Macrocephalae, Poria cocos, coix seed,
Rhizoma atractylodis, gypsum, cassia twig, rhizoma anemarrhenae, the root bark of tree peony, Cortex Phellodendri, Radix Salviae Miltiorrhizae, reticulate millettia, pangolin, damp sunset, centipede, zaocys dhumnade, rhizoma cyperi, corydalis tuber,
The banksia rose, Semen Strychni (processed);
Step (2):The Chinese medicine material weighed in step (1) is placed in clear water and soaks 10-15min, is removed miscellaneous in medicinal powder
Thing;
Step (3):Chinese medicine material obtained by step (2) is pulled out from water, is placed under natural light and dries;Dry rear aqueous
Rate is controlled less than or equal to 98%;
Step (4):Step (3) dried Chinese medicine is placed in grinding machine for Chinese herb medicines and is pulverized, crosses 500-800 mesh sieves point
Afterwards, when sterilization processing 12-24 is small under UV light sterilization lamp;
Step (5):The herb powder that step (4) obtains is fitted into capsule, that is, the Chinese medicinal capsule for the gout that obtains medical treatment.
Pulvis is made in embodiment 8
The preparation method of the Chinese medicine composition for the treatment of gout described in embodiment 1-6, formulation are pulvis, including following step
Suddenly:
Step (1):According to it is described treatment gout Chinese medicine composition parts by weight of raw materials weigh Rhizoma Atractylodis Macrocephalae, Poria cocos, coix seed,
Rhizoma atractylodis, gypsum, cassia twig, rhizoma anemarrhenae, the root bark of tree peony, Cortex Phellodendri, Radix Salviae Miltiorrhizae, reticulate millettia, pangolin, damp sunset, centipede, zaocys dhumnade, rhizoma cyperi, corydalis tuber,
The banksia rose, Semen Strychni (processed);
Step (2):The Chinese medicine material weighed in step (1) is placed in clear water and soaks 10-15min, is removed miscellaneous in medicinal powder
Thing;
Step (3):Chinese medicine material obtained by step (2) is pulled out from water, is placed under natural light and dries;Dry rear aqueous
Rate is controlled less than or equal to 98%;
Step (4):Step (3) dried Chinese medicine is placed in grinding machine for Chinese herb medicines and is pulverized, crosses 500-800 mesh sieves point
Afterwards, when sterilization processing 12-24 is small under UV light sterilization lamp;
Step (5):The herb powder that step (4) obtains is fitted into Chinese medicine net bag, that is, the traditional Chinese medicine powder for the gout that obtains medical treatment
Agent.
Decoction is made in embodiment 9
The preparation method of the Chinese medicine composition for the treatment of gout described in embodiment 1-6, formulation are decoction, including following step
Suddenly:
Step (1):According to it is described treatment gout Chinese medicine composition parts by weight of raw materials weigh Rhizoma Atractylodis Macrocephalae, Poria cocos, coix seed,
Rhizoma atractylodis, gypsum, cassia twig, rhizoma anemarrhenae, the root bark of tree peony, Cortex Phellodendri, Radix Salviae Miltiorrhizae, reticulate millettia, pangolin, damp sunset, centipede, zaocys dhumnade, rhizoma cyperi, corydalis tuber,
The banksia rose, Semen Strychni (processed);
Step (2):The Chinese medicine material weighed in step (1) is placed in medicine pot, and adds clear water immersion 30min, is removed
Debris in medicinal powder;The addition of clear water is advisable with flooding all Chinese medicine materials, after immersion, after boiling by intense fire, and slow boiling heating
30-50 minutes, filter to obtain a liquid;
Step (3):Add clear water in the dregs of a decoction into step (2) in marmite, the addition of clear water is to flood all dregs of a decoction
It is advisable, carries out second and decoct, first boil by intense fire, then be cooked by slow fire 30 minutes, filters to obtain secondary liquid;
Step (4):Gained liquid in step (2) and step (3) is merged, pack, cooled to room temperature is placed on ice
Refrigerated in case, refrigerated storage temperature is controlled at 0-5 DEG C, and the traditional Chinese herbal decoction for the treatment of gout is thus made.
Toxicity test
The suitable Adult mouse 40 of weight is chosen, is divided into control group and administration group, rearing conditions are consistent, and control group is not
Medicine feed, the daily medicine feed of administration group 1 time, records the physical condition of each small white mouse, ingests, drinks water, weight daily, test duration six
A month, compared with control group, administration group small white mouse physical condition, ingest, drink water, body weight increase it is normal, and have no small white mouse
It is sick or dead.Prompt the medicine security good, have no toxic side effect.
The present invention has carried out clinical efficacy tracking with the data given by embodiment 5, and curative effect is summarized as follows:
1. choosing gout case load 450, average age 45 years old, is randomly divided into four groups, treatment group 150 is right by patient
According to data such as group 300, two groups of ages, there was no significant difference, is comparable.
2. treatment method, treatment group takes orally Chinese medicine composition made from optimization formula embodiment 5 of the present invention, per bu sooner or later
Decoction, course for the treatment of 3-5 weeks are taken twice.
3. diagnostic criteria
Reference《Modern Chinese medicine clinical diagnostics》In diagnosis basis carry out clinical diagnosis:
Cure:Joint motion and its shape recover normal, and blood uric acid concentration is normal;
It is effective:Joint motion recovers function substantially, and blood uric acid concentration is decreased obviously;
Improve:Joint movement function has improved, and blood uric acid concentration has declined;
It is invalid:After treatment, symptom does not improve.
Total effective rate=(cure+effective+improve)/n × 100%.
4. clinical observation experiment result:
Case load 450, wherein treatment group 150;Control group 300, control group stochastic averagina are divided into three groups, every group 100
Example.
Treatment group:The preparation method that the prescription used provides for the prescription of embodiment 5, embodiment 9,
Control group 1:Using scarce monarch drug in a prescription (Rhizoma Atractylodis Macrocephalae):A kind of Chinese medicine composition for treating gout, in parts by weight, in this
Drug composition is made of the raw material of following parts by weight:12 parts of Poria cocos, 15 parts of coix seed, 12 parts of rhizoma atractylodis, 20 parts of gypsum, cassia twig 12
Part, 15 parts of rhizoma anemarrhenae, 13 parts of the root bark of tree peony, 13 parts of Cortex Phellodendri, 20 parts of Radix Salviae Miltiorrhizae, 17 parts of reticulate millettia, 13 parts of pangolin, damp 13 parts of sunset, centipede 2
Bar, 18 parts of zaocys dhumnade, 14 parts of rhizoma cyperi, 17 parts of corydalis tuber, 13 parts of the banksia rose, 7 parts of Semen Strychni (processed).
Control group 2:Using scarce ministerial drug (Poria cocos):A kind of Chinese medicine composition for treating gout, in parts by weight, in this
Drug composition is made of the raw material of following parts by weight:16 parts of Rhizoma Atractylodis Macrocephalae, 15 parts of coix seed, 12 parts of rhizoma atractylodis, 20 parts of gypsum, cassia twig 12
Part, 15 parts of rhizoma anemarrhenae, 13 parts of the root bark of tree peony, 13 parts of Cortex Phellodendri, 20 parts of Radix Salviae Miltiorrhizae, 17 parts of reticulate millettia, 13 parts of pangolin, damp 13 parts of sunset, centipede 2
Bar, 18 parts of zaocys dhumnade, 14 parts of rhizoma cyperi, 17 parts of corydalis tuber, 13 parts of the banksia rose, 7 parts of Semen Strychni (processed).
Control group 3:Using scarce ministerial drug (coix seed):A kind of Chinese medicine composition for treating gout, in parts by weight, should
Chinese medicine composition is made of the raw material of following parts by weight:16 parts of Rhizoma Atractylodis Macrocephalae, 12 parts of Poria cocos, 12 parts of rhizoma atractylodis, 20 parts of gypsum, cassia twig 12
Part, 15 parts of rhizoma anemarrhenae, 13 parts of the root bark of tree peony, 13 parts of Cortex Phellodendri, 20 parts of Radix Salviae Miltiorrhizae, 17 parts of reticulate millettia, 13 parts of pangolin, damp 13 parts of sunset, centipede 2
Bar, 18 parts of zaocys dhumnade, 14 parts of rhizoma cyperi, 17 parts of corydalis tuber, 13 parts of the banksia rose, 7 parts of Semen Strychni (processed).
Treatment group, male 75, women 75, age 20-70 Sui, -2 years March of disease time.Treatment cycle is 3-5
The course for the treatment of, cure rate 65%, obvious effective rate 75%, effective percentage 85%.
Control group 1, male 50, women 50, age 20-70 Sui, -2 years March of disease time.Treatment cycle is 3-5
The course for the treatment of, cure rate 3%, obvious effective rate 15%, effective percentage are 30%.
Control group 2, male 50, women 50, age 20-70 Sui, -2 years March of disease time.Treatment cycle is 3-5
The course for the treatment of, cure rate 5%, obvious effective rate 25%, effective percentage are 35%.
Control group 3, male 50, women 50, age 20-70 Sui, -2 years March of disease time.Treatment cycle is 3-5
The course for the treatment of, cure rate 8%, obvious effective rate 10%, effective percentage are 35%.
5. model case
5.1 Chens, Anyang people from Tangyin County, man, 59 years old.Left leg joint is red and swollen, heat pain, involves Minor articulus and ankle, foot,
Blood uric acid is 560umol/L, takes western medicine three months, and curative effect is little, and Uric Acid Content remains high, then to inventor institute
Traditional chinese medical science clinic go to a doctor, give the Chinese medicine of the treatment gout of the embodiment of the present invention 5, after a week, Minor articulus and ankle, foot are no longer swollen
Bitterly, left leg joint is no longer red and swollen after two weeks, hot detection blood uric acid is 352umol/L bitterly, recovery from illness.Visited after half a year:Without recurrence.
5.2 Feng so-and-so, Anyang people from Tangyin County, man, 46 years old.It is right crus of diaphragm ankle heat pain, swelling, stiff, it can not walk, blood urine
Acid is 502umol/L, gives the Chinese medicine of the treatment gout of the embodiment of the present invention 5, after a week, no longer swells and ache, no longer stiff after two weeks
Firmly, it is 349umol/L to detect blood uric acid, recovery from illness.Visited after half a year:Without recurrence.
5.3 Weis so-and-so, man, 43 years old, Anyang people from Tangyin County.Starting within 2001 the causus pain in big toe joint, day at light night is heavy,
It cannot land, wrist, elbow joint pain.Do not improve by western medicines in treatment.In June, the 2007 big breaking-out of arthralgia, purine of moaning.
It cannot land, to county hospital inspection, the increase of blood uric acid concentration, is diagnosed as gout.The embodiment of the present invention is taken from July, 2007
The Chinese medicine of 5 treatment gout, take one week posterior joint not pain, can walk.The activity of medication four weeks posterior joint and its shape
Recover normal, blood uric acid concentration is normal.Cure.
5.4 Ouyang so-and-so, man, 45 years old, Anyang people from Tangyin County.Start within 2006 the causus pain in big toe joint occur, no
It can land, with fever and chills, headache, palpitaition, recurrent exerbation.The causus pain in big toe in October, 1999 joint, big breaking-out, it is impossible to
Ground.Chilly, headache, palpitaition, the increase of blood uric acid concentration, are diagnosed as gout.Through the treatment gout for taking the embodiment of the present invention 5
Chinese medicine is treated, and medication one week joint not pain, can walk;The activity of medication four weeks posterior joint and its shape recover normal,
Blood uric acid concentration is normal.Cure.
5.5 Guo so-and-so, man, 68 years old, Anyang people from Tangyin County.Big toe joint is violent within 2006, and day at light night is heavy, it is impossible to
Ground, wrist joint pain.It is ineffective by western medicines in treatment.Aggravation in 2009, blood uric acid concentration increase, is diagnosed as
Gout.The Chinese medicine of the treatment gout of the embodiment of the present invention 5 is taken from 5 days March in 2009, pain relief after a week, can walk.
The posterior joint activity of four weeks and its shape recover normal, and blood uric acid concentration is normal.Cure.
5.6 it is deep so-and-so, female, 24 years old, Anyang people from Tangyin County.Start within 2008 the causus pain in sufficient big toe joint, it is impossible to
Ground, has palpitation, palpitaition.It is gout through examination in hospital.In January, 2008 takes the Chinese medicine of the treatment gout of the embodiment of the present invention 5, and one
Pain relief after week, joint motion freely, can walk.The posterior joint activity of five weeks and its shape recover normal, blood urine
Acid concentration is normal.Cure.
The foregoing description of the disclosed embodiments, enables professional and technical personnel in the field to realize or use the present invention.
A variety of modifications to these embodiments will be apparent for those skilled in the art, as defined herein
General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, it is of the invention
The embodiments shown herein is not intended to be limited to, but more to be met and the principles and novel features disclosed herein phase
Consistent most wide scope.
Claims (8)
1. a kind of Chinese medicine composition for treating gout, it is characterised in that in parts by weight, the Chinese medicine composition is by following parts by weight
Raw material composition:10~20 parts of Rhizoma Atractylodis Macrocephalae, 10~15 parts of Poria cocos, 10~20 parts of coix seed, 10~15 parts of rhizoma atractylodis, gypsum 15~30
Part, 10~15 parts of cassia twig, 10~20 parts of rhizoma anemarrhenae, 10~15 parts of the root bark of tree peony, 10~15 parts of Cortex Phellodendri, 10~30 parts of Radix Salviae Miltiorrhizae, reticulate millettia 15
~20 parts, 10~15 parts of pangolin, damp 10~20 parts of sunset, centipede 2,15~20 parts of zaocys dhumnade, 10~15 parts of rhizoma cyperi, corydalis tuber 10
~20 parts, 10~15 parts of the banksia rose, 6~9 parts of Semen Strychni (processed).
2. the Chinese medicine composition for the treatment of gout according to claim 1, it is characterised in that in parts by weight, the Chinese medicine group
Compound is made of the raw material of following parts by weight:15~18 parts of Rhizoma Atractylodis Macrocephalae, 11~13 parts of Poria cocos, 13~18 parts of coix seed, rhizoma atractylodis 12~
13 parts, 18~25 parts of gypsum, 11~14 parts of cassia twig, 13~18 parts of rhizoma anemarrhenae, 12~15 parts of the root bark of tree peony, 12~15 parts of Cortex Phellodendri, Radix Salviae Miltiorrhizae 18
~26 parts, 17~19 parts of reticulate millettia, 12~15 parts of pangolin, damp 10~18 parts of sunset, centipede 2,16~20 parts of zaocys dhumnade, rhizoma cyperi
13~15 parts, 15~20 parts of corydalis tuber, 10~15 parts of the banksia rose, 6~9 parts of Semen Strychni (processed).
3. the Chinese medicine composition for the treatment of gout according to claim 2, it is characterised in that in parts by weight, the Chinese medicine group
Compound is made of the raw material of following parts by weight:16 parts of Rhizoma Atractylodis Macrocephalae, 12 parts of Poria cocos, 15 parts of coix seed, 12 parts of rhizoma atractylodis, 20 parts of gypsum, osmanthus
12 parts of branch, 15 parts of rhizoma anemarrhenae, 13 parts of the root bark of tree peony, 13 parts of Cortex Phellodendri, 20 parts of Radix Salviae Miltiorrhizae, 17 parts of reticulate millettia, 13 parts of pangolin, damp 13 parts of sunset, Wu
Centipede 2,18 parts of zaocys dhumnade, 14 parts of rhizoma cyperi, 17 parts of corydalis tuber, 13 parts of the banksia rose, 7 parts of Semen Strychni (processed).
4. the Chinese medicine composition for the treatment of gout according to claim 2, it is characterised in that in parts by weight, the Chinese medicine group
Compound is made of the raw material of following parts by weight:17 parts of Rhizoma Atractylodis Macrocephalae, 13 parts of Poria cocos, 16 parts of coix seed, 13 parts of rhizoma atractylodis, 23 parts of gypsum, osmanthus
13 parts of branch, 17 parts of rhizoma anemarrhenae, 14 parts of the root bark of tree peony, 14 parts of Cortex Phellodendri, 24 parts of Radix Salviae Miltiorrhizae, 18 parts of reticulate millettia, 14 parts of pangolin, damp 16 parts of sunset, Wu
Centipede 2,19 parts of zaocys dhumnade, 15 parts of rhizoma cyperi, 18 parts of corydalis tuber, 15 parts of the banksia rose, 8 parts of Semen Strychni (processed).
5. according to the Chinese medicine composition of any treatment gouts of claim 1-4, it is characterised in that the Chinese medicine composition can
Any one in pulvis, capsule and decoction is made.
6. according to the preparation method of the Chinese medicine composition of any treatment gouts of claim 1-4, formulation is capsule, it is special
Sign is, includes the following steps:
Step (1):Parts by weight of raw materials according to the Chinese medicine composition of the treatment gout weighs Rhizoma Atractylodis Macrocephalae, Poria cocos, coix seed, grey
Art, gypsum, cassia twig, rhizoma anemarrhenae, the root bark of tree peony, Cortex Phellodendri, Radix Salviae Miltiorrhizae, reticulate millettia, pangolin, damp sunset, centipede, zaocys dhumnade, rhizoma cyperi, corydalis tuber, wood
Fragrant, Semen Strychni (processed);
Step (2):The Chinese medicine material weighed in step (1) is placed in clear water and soaks 10-15min, removes debris in medicinal powder;
Step (3):Chinese medicine material obtained by step (2) is pulled out from water, is placed under natural light and dries;Dry rear moisture content control
System is less than or equal to 98%;
Step (4):Step (3) dried Chinese medicine is placed in grinding machine for Chinese herb medicines and is pulverized, after crossing 500-800 mesh sieves point,
When sterilization processing 12-24 is small under UV light sterilization lamp;
Step (5):The herb powder that step (4) obtains is filled in capsule, that is, the Chinese medicinal capsule for the gout that obtains medical treatment.
7. according to the preparation method of the Chinese medicine composition of any treatment gouts of claim 1-4, formulation is pulvis, it is special
Sign is, includes the following steps:
Step (1):Parts by weight of raw materials according to the Chinese medicine composition of the treatment gout weighs Rhizoma Atractylodis Macrocephalae, Poria cocos, coix seed, grey
Art, gypsum, cassia twig, rhizoma anemarrhenae, the root bark of tree peony, Cortex Phellodendri, Radix Salviae Miltiorrhizae, reticulate millettia, pangolin, damp sunset, centipede, zaocys dhumnade, rhizoma cyperi, corydalis tuber, wood
Fragrant, Semen Strychni (processed);
Step (2):The Chinese medicine material weighed in step (1) is placed in clear water and soaks 10-15min, removes debris in medicinal powder;
Step (3):Chinese medicine material obtained by step (2) is pulled out from water, is placed under natural light and dries;Dry rear moisture content control
System is less than or equal to 98%;
Step (4):Step (3) dried Chinese medicine is placed in grinding machine for Chinese herb medicines and is pulverized, after crossing 500-800 mesh sieves point,
When sterilization processing 12-24 is small under UV light sterilization lamp;
Step (5):The herb powder that step (4) obtains is fitted into Chinese medicine net bag, that is, the Chinese medicine powder for the gout that obtains medical treatment.
8. according to the preparation method of the Chinese medicine composition of any treatment gouts of claim 1-4, formulation is decoction, it is special
Sign is, includes the following steps:
Step (1):Parts by weight of raw materials according to the Chinese medicine composition of the treatment gout weighs Rhizoma Atractylodis Macrocephalae, Poria cocos, coix seed, grey
Art, gypsum, cassia twig, rhizoma anemarrhenae, the root bark of tree peony, Cortex Phellodendri, Radix Salviae Miltiorrhizae, reticulate millettia, pangolin, damp sunset, centipede, zaocys dhumnade, rhizoma cyperi, corydalis tuber, wood
Fragrant, Semen Strychni (processed);
Step (2):The Chinese medicine material weighed in step (1) is placed in medicine pot, and adds clear water immersion 30min, removes medicinal powder
Middle debris;The addition of clear water is advisable with flooding all Chinese medicine materials, after immersion, after boiling by intense fire, and slow boiling heating 30-50
Minute, filter to obtain a liquid;
Step (3):Clear water is added in the dregs of a decoction into step (2) in marmite, the addition of clear water is advisable with flooding all dregs of a decoction,
Carry out second to decoct, first boil by intense fire, then be cooked by slow fire 30 minutes, filter to obtain secondary liquid;
Step (4):Gained liquid in step (2) and step (3) is merged, pack, cooled to room temperature is placed in refrigerator
Refrigeration, refrigerated storage temperature are controlled at 0-5 DEG C, and the traditional Chinese herbal decoction for the treatment of gout is thus made.
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