CN102293851B - Externally applied traditional Chinese medicine preparation for treating exudation type eczema in babies and preparation method thereof - Google Patents
Externally applied traditional Chinese medicine preparation for treating exudation type eczema in babies and preparation method thereof Download PDFInfo
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Abstract
The invention discloses an externally applied traditional Chinese medicine preparation for treating exudation type eczema in babies and a preparation method thereof. The externally applied traditional Chinese medicine preparation is prepared from 5 to 15 parts by weight of divaricate saposhnikovia root, 5 to 15 parts by weight of fructus forsythiae, 2 to 8 parts by weight of indigo naturalis, 5 to 10 parts by weight of patrinia, 3 to 8 parts by weight of radix sophorae flavescentis, 3 to 8 parts by weight of common cnidium fruit, 5 to 10 parts by weight of amur corktree bark, 5 to 15 parts by weight of rheum officinale, 3 to 8 parts by weight of root of large-flowered skullcap and 3 to 8 parts by weight of calamine. A result of a test shows that the externally applied traditional Chinese medicine preparation for treating exudation type eczema in babies can treat exudation type eczema in babies effectively, wherein through the externally applied traditional Chinese medicine preparation for treating exudation type eczema in babies, babies with mild symptoms can be cured in 3 to 4 days and babies with serious symptoms can be cured in two courses of treatment. The externally applied traditional Chinese medicine preparation for treating exudation type eczema in babies has the advantages of simple treatment mode, convenience of use, no pain in treatment, short onset time, high safety, no toxic and side effect, high cure rate reaching above 80%, low cost and no recurrence after cure.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method for the treatment of infantile eczema.
Background technology
Infantile eczema (infantileeczema) is a kind of a kind of allergic skin inflammation common, that caused by internal and external factor.Skin lesion shows effect repeatedly take papulovesicle as main pleomorphism infringement, and the acute and chronic phase overlaps alternately, accompanies violent pruritus.Eczema can be divided into three types by skin lesion, i.e. seborrhea, exudative type and drying type.Exudative type is more common in 3~6 months fat babies.Come across first Head And Face.Except being difficult for around the mouth and nose occuring, the red little pimple of the visible symmetry small rice grain size of two buccals has phlysis and erythema, the substrate edema, and the lamellar erosion is oozed out, and yellow serosity incrustation is thicker.Common hemorrhage because scratching, the soft crust of yellowish-brown is arranged.Expose the wet mashed face of cerise after peelling off crust, be graininess, the surface is easily hemorrhage.Such as untimely treatment, can be to trunk, extremity and whole body spread, and can secondary infection.During falling ill, infant is because the pain of itching is understood dysphoria, and cry and scream night, has a strong impact on sleep.
The infantile eczema sickness rate is higher at present, and easily repeatedly, child is because too little, misery can not be expressed after being ill, only can cry and scream, so that father and mother and other heads of a family feel both distressed, very thorny again, after hospital, medicine commonly used is some hormones external preparation, onset during medication, after the drug withdrawal namely repeatedly, add that again baby's health is small and weak, use hormone can produce many side effect.
The traditional Chinese medical science thinks that eczema is main relevant with damp, but wet intrinsic heat, and sending out is damp and hot card, take clearing away heat-damp and promoting diuresis as main, some irritated factors also easily cause eczema simultaneously, therefore should also be noted that antiallergic during treatment, for exudative type eczema, should also be noted that antiinflammatory, promote wound surface more after.Radix Scutellariae, Fructus Forsythiae all have the effect of heat-clearing and toxic substances removing in the prescription of the present invention; Indigo Naturalis, Herba Patriniae, Radix Et Rhizoma Rhei share, and have the effect of heat-clearing and toxic substances removing, removing heat from blood, antiinflammatory; Radix Saposhnikoviae has heat clearing away, antianaphylactic effect; Radix Sophorae Flavescentis, Cortex Phellodendri are share, and have the effect of stronger clearing heat and expelling damp; Fructus Cnidii has the effect of killing parasites for relieving itching; Calamina can absorb wound extract, and convergence, protective effect are arranged, and still can suppress local staphylococcic growth.
But not document record, above-mentioned prescription have the effect for the treatment of baby exudative type eczema.
Summary of the invention
The objective of the invention is to overcome the deficiencies in the prior art, a kind of Chinese medicine for outer use of the baby's for the treatment of exudative type eczema is provided.
Second purpose of the present invention provides a kind of preparation method of Chinese medicine for outer use of the baby's for the treatment of exudative type eczema.
Technical scheme of the present invention is summarized as follows:
A kind of Chinese medicine for outer use for the treatment of baby's exudative type eczema is made by following raw materials according: 3~8 parts of 5~15 parts of Radix Saposhnikoviaes, 5~15 parts of Fructus Forsythiaes, 3~8 parts of Indigo Naturaliss, 5~10 parts of Herba Patriniae, 3~8 parts of Radix Sophorae Flavescentiss, 3~8 parts of Fructus Cnidiis, 5~10 parts of Cortex Phellodendris, 5~15 parts of Radix Et Rhizoma Rhei, 3~8 parts of Radix Scutellariaes and Calaminas by weight.
Preferably: described Radix Saposhnikoviae is 7~10 parts, 7~10 parts of Fructus Forsythiaes, 4~6 parts of Indigo Naturaliss, 6~8 parts of Herba Patriniae, 4~6 parts of Radix Sophorae Flavescentiss, 4~6 parts of Fructus Cnidiis, 6~8 parts of Cortex Phellodendris, 7~10 parts of Radix Et Rhizoma Rhei, 4~6 parts of Radix Scutellariaes, 4~6 parts of Calaminas.
A kind of preparation method for the treatment of the Chinese medicine for outer use of baby's exudative type eczema comprises the steps:
(1) takes by weighing by weight following raw materials according: 3~8 parts of 5~15 parts of Radix Saposhnikoviaes, 5~15 parts of Fructus Forsythiaes, 3~8 parts of Indigo Naturaliss, 5~10 parts of Herba Patriniae, 3~8 parts of Radix Sophorae Flavescentiss, 3~8 parts of Fructus Cnidiis, 5~10 parts of Cortex Phellodendris, 5~15 parts of Radix Et Rhizoma Rhei, 3~8 parts of Radix Scutellariaes and Calaminas;
(2) be 1 in mass ratio: the ratio of 6-8, described Radix Saposhnikoviae, Fructus Forsythiae, Indigo Naturalis, Herba Patriniae, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Phellodendri, Radix Et Rhizoma Rhei and Radix Scutellariae are decocted with water twice, each 1.5h-2h that decocts, filter, filtrate is merged, and concentrated, the weight ratio that makes concentrated solution and raw material is 1: 1, micron-sized Calamina powder is mixed with described concentrated solution, namely make a kind of Chinese medicine for outer use of the baby's for the treatment of exudative type eczema.
Preferably: described Radix Saposhnikoviae is 7~10 parts, 7~10 parts of Fructus Forsythiaes, 4~6 parts of Indigo Naturaliss, 6~8 parts of Herba Patriniae, 4~6 parts of Radix Sophorae Flavescentiss, 4~6 parts of Fructus Cnidiis, 6~8 parts of Cortex Phellodendris, 7~10 parts of Radix Et Rhizoma Rhei, 4~6 parts of Radix Scutellariaes, 4~6 parts of Calaminas.
Evidence, the Chinese medicine for outer use for the treatment of baby exudative type eczema of the present invention can effectively be treated baby's exudative type eczema, and slight infant can be fully recovered in 3~4 days, needed two courses for the treatment of for heavier infant.Use that preparation for treating mode of the present invention is simple, infant is easy to use, no pain in the therapeutic process, instant effect, safe, have no side effect, cure rate can reach more than 80%, and it is low to have a cost, the advantage such as does not recur after more.
The specific embodiment
The present invention is further illustrated below in conjunction with specific embodiment.
Embodiment 1
A kind of preparation method for the treatment of the Chinese medicine for outer use of baby's exudative type eczema comprises the steps:
(1) takes by weighing by weight following raw materials according: 5 parts of 8 parts of Radix Saposhnikoviaes, 8 parts of Fructus Forsythiaes, 5 parts of Indigo Naturaliss, 7 parts of Herba Patriniae, 5 parts of Radix Sophorae Flavescentiss, 5 parts of Fructus Cnidiis, 7 parts of Cortex Phellodendris, 8 parts of Radix Et Rhizoma Rhei, 5 parts of Radix Scutellariaes and Calaminas;
(2) Radix Saposhnikoviae, Fructus Forsythiae, Indigo Naturalis, Herba Patriniae, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Phellodendri, Radix Et Rhizoma Rhei and Radix Scutellariae are decocted with water twice, add water 8 times of weight for the first time, decoct 2h, filter, get filtrate, filtering residue is added water 6 times of weight, decoct 1.5h, filter, filtrate, twice filtrate is merged, being concentrated into the medical material weight ratio is 1: 1 concentrated solution, micron-sized Calamina powder is mixed with described concentrated solution, namely make a kind of Chinese medicine for outer use of the baby's for the treatment of exudative type eczema.
Embodiment 2
A kind of preparation method for the treatment of the Chinese medicine for outer use of baby's exudative type eczema comprises the steps:
(1) takes by weighing by weight following raw materials according: 8 parts of 5 parts of Radix Saposhnikoviaes, 15 parts of Fructus Forsythiaes, 6 parts of Indigo Naturaliss, 6 parts of Herba Patriniae, 3 parts of Radix Sophorae Flavescentiss, 8 parts of Fructus Cnidiis, 8 parts of Cortex Phellodendris, 7 parts of Radix Et Rhizoma Rhei, 3 parts of Radix Scutellariaes and Calaminas;
(2) Radix Saposhnikoviae, Fructus Forsythiae, Indigo Naturalis, Herba Patriniae, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Phellodendri, Radix Et Rhizoma Rhei and Radix Scutellariae are decocted with water twice, add water 8 times of weight for the first time, decoct 2h, filter, get filtrate, filtering residue is added water 8 times of weight, decoct 1.5h, filter, filtrate, twice filtrate is merged, being concentrated into the medical material weight ratio is 1: 1 concentrated solution, micron-sized Calamina powder is mixed with described concentrated solution, namely make a kind of Chinese medicine for outer use of the baby's for the treatment of exudative type eczema.
Embodiment 3
A kind of preparation method for the treatment of the Chinese medicine for outer use of baby's exudative type eczema comprises the steps:
(1) takes by weighing by weight following raw materials according: 3 parts of 7 parts of Radix Saposhnikoviaes, 5 parts of Fructus Forsythiaes, 8 parts of Indigo Naturaliss, 8 parts of Herba Patriniae, 4 parts of Radix Sophorae Flavescentiss, 3 parts of Fructus Cnidiis, 10 parts of Cortex Phellodendris, 10 parts of Radix Et Rhizoma Rhei, 4 parts of Radix Scutellariaes and Calaminas;
(2) Radix Saposhnikoviae, Fructus Forsythiae, Indigo Naturalis, Herba Patriniae, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Phellodendri, Radix Et Rhizoma Rhei and Radix Scutellariae are decocted with water twice, add water 6 times of weight for the first time, decoct 2h, filter, get filtrate, filtering residue is added water 6 times of weight, decoct 1.5h, filter, filtrate, twice filtrate is merged, being concentrated into the medical material weight ratio is 1: 1 concentrated solution, micron-sized Calamina powder is mixed with described concentrated solution, namely make a kind of Chinese medicine for outer use of the baby's for the treatment of exudative type eczema.
Embodiment 4
A kind of preparation method for the treatment of the Chinese medicine for outer use of baby's exudative type eczema comprises the steps:
(1) takes by weighing by weight following raw materials according: 4 parts of 10 parts of Radix Saposhnikoviaes, 7 parts of Fructus Forsythiaes, 3 parts of Indigo Naturaliss, 10 parts of Herba Patriniae, 6 parts of Radix Sophorae Flavescentiss, 4 parts of Fructus Cnidiis, 5 parts of Cortex Phellodendris, 15 parts of Radix Et Rhizoma Rhei, 6 parts of Radix Scutellariaes and Calaminas;
(2) Radix Saposhnikoviae, Fructus Forsythiae, Indigo Naturalis, Herba Patriniae, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Phellodendri, Radix Et Rhizoma Rhei and Radix Scutellariae are decocted with water twice, add water 8 times of weight for the first time, decoct 2h, filter, get filtrate, filtering residue is added water 8 times of weight, decoct 2h, filter, filtrate, twice filtrate is merged, being concentrated into the medical material weight ratio is 1: 1 concentrated solution, micron-sized Calamina powder is mixed with described concentrated solution, namely make a kind of Chinese medicine for outer use of the baby's for the treatment of exudative type eczema.
Embodiment 5
A kind of preparation method for the treatment of the Chinese medicine for outer use of baby's exudative type eczema comprises the steps:
(1) takes by weighing by weight following raw materials according: 6 parts of 15 parts of Radix Saposhnikoviaes, 10 parts of Fructus Forsythiaes, 4 parts of Indigo Naturaliss, 5 parts of Herba Patriniae, 8 parts of Radix Sophorae Flavescentiss, 6 parts of Fructus Cnidiis, 6 parts of Cortex Phellodendris, 5 parts of Radix Et Rhizoma Rhei, 8 parts of Radix Scutellariaes and Calaminas;
(2) Radix Saposhnikoviae, Fructus Forsythiae, Indigo Naturalis, Herba Patriniae, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Phellodendri, Radix Et Rhizoma Rhei and Radix Scutellariae are decocted with water twice, add water 8 times of weight for the first time, decoct 1.5h, filter, get filtrate, filtering residue is added water 8 times of weight, decoct 1.5h, filter, filtrate, twice filtrate is merged, being concentrated into the medical material weight ratio is 1: 1 concentrated solution, micron-sized Calamina powder is mixed with described concentrated solution, namely make a kind of Chinese medicine for outer use of the baby's for the treatment of exudative type eczema.
Using method is that Chinese medicine preparation of the present invention is applied in affected part, erythra surface with cotton swab, is coated with every day 3 times, and 5 days is a course for the treatment of.
Clinical trial:
One, clinical data:
Exudative type eczema infant 80 examples, boy baby's 49 examples wherein, girl baby's 31 examples, age reckling 2 months 03 days, 7 first quarter moons of the maximum have 65 examples to have with after the other drug treatment in the infant, invalid or effect is relatively poor or the treatment of repeatedly outbreak experience.
Two, clinical observation:
After using preparation of the present invention (embodiment 1 preparation) treatment, antalgesic-antipruritic immediately, the infant wound fluid reduces immediately, fades away, and wound surface progressively heals, and the lighter is coated with 3~4 days and can fully recovers, and uses to fully recover 2 courses for the treatment of than severe one.
Three, concrete therapeutic outcome:
After using Drug therapy of the present invention, cure infant 64 examples, account for 80%; Effective 12 examples account for 15%; Not obvious person's 4 examples of therapeutic effect account for 5%.
Four, model case:
1, certain boy baby, 2 first quarter moons, when 1 first quarter moon is large, find eczema, the beginning head of a family be not present to the mind very much, after increase the weight of gradually, during by two months, face by beginning develops into cervical region, chest, and light during by firm find of eczema, sparse erythema is developed to erythema in blocks, and following transudate to occur, baby always cries and screams, not yum-yum milk, father and mother are with it to children's hospital, used the hormones external-applied ointment, symptom has obtained alleviation when bringing into use, but symptom namely occurs after the drug withdrawal, even increase the weight of, it is very thorny that father and mother feel, then use this Chinese medicine after, symptom has obtained alleviation very soon, second day after using, the infant number of times of crying and screaming obviously reduces, used for one and half courses for the treatment of after, infant is is no longer cry and screamed, food milk amount has increased by one times nearly, and epidermis loses transudate substantially, the macule major part is thin out even disappear, after continued again to have used state of an illness recovery from illness 3 days.Carried out Effect of follow-up visit by telephone in 1 month afterwards, not again morbidity.
2, certain baby, 7 months, in the time of 4 months, begin to find eczema, the head of a family thinks that it takes the anaphylaxis of some compositions in the milk powder, changed immediately its brand milk powder of taking, after taking new milk powder, the infant symptom has obtained some alleviations, can probably cross two weeks after, the infant symptom begins again to increase the weight of, eczema is developed to face by original cervical region, head and arm, and hemophoric yellow transudate appears, and ceaselessly cry and scream at night, ceaselessly scratch the affected part with little hands, some other external preparation even folk prescriptions have also been used during this time, but curative effect is all undesirable, uses behind this Chinese medicine the 3rd day, and infant was changed into by former crying and screaming has has whole night only cry and screamed 1 time, no longer cry and scream at night after using a course for the treatment of, continue again afterwards to have used a course for the treatment of, transudate and macule all disappear, and crust comes off naturally, skin is soft, the infant recovery from illness.By Effect of follow-up visit by telephone, not again recurrence.
The preparation that experiment showed, embodiment 2-embodiment 5 preparations also has similar result.
Claims (4)
1. Chinese medicine for outer use for the treatment of baby's exudative type eczema is characterized in that being made by following raw materials according by weight: 3~8 parts of 5~15 parts of Radix Saposhnikoviaes, 5~15 parts of Fructus Forsythiaes, 3~8 parts of Indigo Naturaliss, 5~10 parts of Herba Patriniae, 3~8 parts of Radix Sophorae Flavescentiss, 3~8 parts of Fructus Cnidiis, 5~10 parts of Cortex Phellodendris, 5~15 parts of Radix Et Rhizoma Rhei, 3~8 parts of Radix Scutellariaes and Calaminas.
2. the Chinese medicine for outer use for the treatment of according to claim 1 baby exudative type eczema is characterized in that described Radix Saposhnikoviae is 7~10 parts, 7~10 parts of Fructus Forsythiaes, 4~6 parts of Indigo Naturaliss, 6~8 parts of Herba Patriniae, 4~6 parts of Radix Sophorae Flavescentiss, 4~6 parts of Fructus Cnidiis, 6~8 parts of Cortex Phellodendris, 7~10 parts of Radix Et Rhizoma Rhei, 4~6 parts of Radix Scutellariaes, 4~6 parts of Calaminas.
3. a preparation method for the treatment of the Chinese medicine for outer use of baby's exudative type eczema is characterized in that comprising the steps:
(1) takes by weighing by weight following raw materials according: 3~8 parts of 5~15 parts of Radix Saposhnikoviaes, 5~15 parts of Fructus Forsythiaes, 3~8 parts of Indigo Naturaliss, 5~10 parts of Herba Patriniae, 3~8 parts of Radix Sophorae Flavescentiss, 3~8 parts of Fructus Cnidiis, 5~10 parts of Cortex Phellodendris, 5~15 parts of Radix Et Rhizoma Rhei, 3~8 parts of Radix Scutellariaes and Calaminas;
(2) be 1 in mass ratio: the ratio of 6-8, described Radix Saposhnikoviae, Fructus Forsythiae, Indigo Naturalis, Herba Patriniae, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Phellodendri, Radix Et Rhizoma Rhei and Radix Scutellariae are decocted with water twice, each 1.5h-2h that decocts, filter, filtrate is merged, and concentrated, the weight ratio that makes concentrated solution and raw material is 1: 1, micron-sized Calamina powder is mixed with described concentrated solution, namely make a kind of Chinese medicine for outer use of the baby's for the treatment of exudative type eczema.
4. a kind of preparation method for the treatment of the Chinese medicine for outer use of baby's exudative type eczema according to claim 3 is characterized in that described Radix Saposhnikoviae is 7~10 parts, 7~10 parts of Fructus Forsythiaes, 4~6 parts of Indigo Naturaliss, 6~8 parts of Herba Patriniae, 4~6 parts of Radix Sophorae Flavescentiss, 4~6 parts of Fructus Cnidiis, 6~8 parts of Cortex Phellodendris, 7~10 parts of Radix Et Rhizoma Rhei, 4~6 parts of Radix Scutellariaes, 4~6 parts of Calaminas.
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