CN103877393A - Traditional Chinese medicine composition for treating traumatic gonarthromeningitis and application of composition - Google Patents
Traditional Chinese medicine composition for treating traumatic gonarthromeningitis and application of composition Download PDFInfo
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- CN103877393A CN103877393A CN201410072781.5A CN201410072781A CN103877393A CN 103877393 A CN103877393 A CN 103877393A CN 201410072781 A CN201410072781 A CN 201410072781A CN 103877393 A CN103877393 A CN 103877393A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating traumatic gonarthromeningitis and an application of the composition. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 21-30 parts of rhizoma atractylodis, 21-30 parts of eclipta alba, 9-16 parts of dendrobe, 11-20 parts of rhizoma bletillae, 11-20 parts of glechoma hedracea, 5-11 parts of pangolin scales, 25-37 parts of cassia twig, 25-37 parts of nux vomica and 15-24 parts of mouse ears. The traditional Chinese medicine composition provided by the invention can promote blood circulation of joints and surrounding tissues by local medication to protect the synovial membrane, change the condition of nutrition, reduce inflammation exudation and promote absorption of the synovial fluid so as to relieve the symptoms of ankylosis, edema and pains.
Description
Technical field
The invention belongs to Chinese medicine technical field, in particular to a kind of medicine for the treatment of Treatment of knee joint acute traumatic synovitis, relate in particular to a kind of Chinese medicine composition and application thereof for the treatment of Treatment of knee joint acute traumatic synovitis.
Background technology
Traumatic synovitis of knee joint refers to that acute and chronic wound makes knee joint synovial tissue be subject to the stimulation of machinery, biology, chemical, cause synovial membrane congestion and edema, synovial fluid excessive secretion, absorption reduce, thereby produce the disease taking the outbreak repeatedly of knee joint swelling pain, function limitation, amyotrophy etc. as main clinical manifestation.At the clinical general fixing joints that adopt, the methods such as arthrocentesiS and injection meticortelone are treated more.Because these methods can cause pain to patient, and the course for the treatment of of treatment is long, and the absorption of intraarticular hydrops is slow, thereby easily causes atrophy of quadriceps femoris and joint accretion, thereby has affected the therapeutic effect of sufferer.
Summary of the invention
The deficiency existing when Treatment of knee joint acute traumatic synovitis in treatment in view of doctor trained in Western medicine, the object of the present invention is to provide a kind of Chinese medicine composition and application thereof for the treatment of Treatment of knee joint acute traumatic synovitis, this medicine determined curative effect, few side effects, bring misery to patient when medication hardly.
In order to realize object of the present invention, inventor studies and persistent exploration by lot of experiments, has finally obtained following technical scheme:
Treat a Chinese medicine composition for Treatment of knee joint acute traumatic synovitis, this Chinese medicine composition is prepared from by the traditional Chinese medicinal material raw materials of following weight portion: Rhizoma Atractylodis 21-30 part, Herba Ecliptae 21-30 part, Herba Dendrobii 9-16 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 11-20 part, Herba Glechomae 11-20 part, Squama Manis 5-11 part, Ramulus Cinnamomi 25-37 part, Semen Strychni 25-37 part, Ramulus et Folium Berchemiae Lineatae 15-24 part.
Preferably, the Chinese medicine composition for the treatment of Treatment of knee joint acute traumatic synovitis as mentioned above, it is prepared from by the traditional Chinese medicinal material raw materials of following weight portion: Rhizoma Atractylodis 23-27 part, Herba Ecliptae 23-27 part, Herba Dendrobii 11-13 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 13-17 part, Herba Glechomae 13-17 part, Squama Manis 7-9 part, Ramulus Cinnamomi 29-32 part, Semen Strychni 29-32 part, Ramulus et Folium Berchemiae Lineatae 18-20 part.
In a most preferred embodiment of the present invention, the Chinese medicine composition for the treatment of Treatment of knee joint acute traumatic synovitis as mentioned above, it is prepared from by the traditional Chinese medicinal material raw materials of following weight portion: 25 parts of Rhizoma Atractylodis, 25 parts of Herba Ecliptaes, 12 parts of Herba Dendrobiis, 15 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 15 parts of Herba Glechomaes, 8 parts of Squama Manis, 30 parts of Ramulus Cinnamomi, 30 parts of Semen Strychni, 19 parts of Ramulus et Folium Berchemiae Lineataes.
Again further preferably, treat as mentioned above the Chinese medicine composition of Treatment of knee joint acute traumatic synovitis, it is external preparation, comprises gel, ointment.
The gel the present invention relates to or the preparation method of ointment comprise the steps: to take Rhizoma Atractylodis 21-30 part, Herba Ecliptae 21-30 part, Herba Dendrobii 9-16 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 11-20 part, Herba Glechomae 11-20 part, Squama Manis 5-11 part, Ramulus Cinnamomi 25-37 part, Semen Strychni 25-37 part and Ramulus et Folium Berchemiae Lineatae 15-24 part, be placed in mix homogeneously in jacketed pan, add water and cover powder 2cm, soak 10-30 minute, heated and boiled 1h, cooled and filtered, the filtering residue appropriate post-heating that adds water again boils 1h, refilter, twice filtrate is merged, be condensed into extractum, 78～82 DEG C of dry getting dry extract, again dried cream powder was broken into 150 object fine powders, powder gets dry extract, be prepared into gel with common process again, ointment.
Study discovery by lot of experiments, the Treatment of knee joint acute traumatic synovitis patient's that Chinese medicine composition of the present invention causes mechanical factor after by local external application for curing curative effect highly significant, side effect is simultaneously little, and patient institute suffer is little.Therefore, second object of the present invention is to provide a kind of pharmaceutical applications, i.e. the application of above-mentioned Chinese medicine composition in the external used medicine of preparation treatment Treatment of knee joint acute traumatic synovitis.
Compared with prior art, Chinese medicinal external application treatment Treatment of knee joint acute traumatic synovitis can play relaxing muscles and tendons to promote blood circulation, reducing swelling and alleviating pain, promoting blood circulation to remove blood stasis, the effect of expelling wind and cold.Especially adopt Chinese medicine dried cream powder mass external application for curing of the present invention; it is extremely strong at local penetration, and drug molecule absorbs and participates in blood circulation through skin, through affected part; by skin conductance to meridians, muscles and bones; thereby excite the regulatory function of human body to promote the blood circulation of joint and surrounding tissue, protection synovial membrane, improves nutritional status; reducing inflammation oozes out; promote joint fluid to absorb, to remove ankylosis, edema, pain symptom, reach healing object thereby promotion functions recovers.
Detailed description of the invention
It should be noted that, the traditional Chinese medicinal material raw materials that various embodiments of the present invention adopt has following source: Rhizoma Atractylodis are selected feverfew Atractylodes lancea (Thunb.) DC. Atractylodes lancea(Thunb.) dry rhizome of DC..Herba Ecliptae is selected the dry aerial parts of feverfew Eclipta prostrata Eclipta prostrata L..Herba Dendrobii is selected the dry stem of orchid dendrobium loddigesii Rolfe Dendrobium loddigesii Rolfe..Pseudobulbus Bletillae (Rhizoma Bletillae) is selected orchid Pseudobulbus Bletillae (Rhizoma Bletillae) Bletilla striata(Thunb.) dry tuber of Reichb.f..Herba Glechomae is selected from the dry aerial parts into Labiatae herbaceos perennial HUOXUEDAN (Glechomalongituba (Nakai) Kupr.).Squama Manis is selected the scute into Manidae animal Manitis.Ramulus Cinnamomi is selected the dry twig of Lauraceae aiphyllium plant Cortex Cinnamomi.Semen Strychni is selected the dry mature seed of loganiaceae plant Semen Strychni Strychnos nuxvomica L..Ramulus et Folium Berchemiae Lineatae is selected the dry young stem and leaf of Rhamnaceae plant Ramulus et Folium Berchemiae Lineatae Berchemia lineata (L.) DC..
Be below specific embodiments of the invention, technical scheme of the present invention is done to further description, but protection scope of the present invention is not limited to these embodiment.Every do not deviate from the change of the present invention design or be equal to substitute include within protection scope of the present invention.
The preparation of embodiment 1 Chinese medicine dried cream powder
Take Rhizoma Atractylodis 2.5kg, Herba Ecliptae 2.5kg, Herba Dendrobii 1.5kg, Pseudobulbus Bletillae (Rhizoma Bletillae) 1.5kg, Herba Glechomae 1.5kg, Squama Manis 0.8kg, Ramulus Cinnamomi 3.0kg, Semen Strychni 3.0kg and Ramulus et Folium Berchemiae Lineatae 1.9kg, be placed in mix homogeneously in jacketed pan, add water and cover powder 2cm, soak 20 minutes, heated and boiled 1h, cooled and filtered, the filtering residue appropriate post-heating that adds water again boils 1h, refilter, twice filtrate is merged, be condensed into extractum, 80 DEG C of dry getting dry extract, dried cream powder was broken into 150 object fine powders, powder gets dry extract again.
The preparation of embodiment 2 Chinese medicine dried cream powders
Take Rhizoma Atractylodis 2.1kg, Herba Ecliptae 2.5kg, Herba Dendrobii 1.2kg, Pseudobulbus Bletillae (Rhizoma Bletillae) 2.0kg, Herba Glechomae 1.5kg, Squama Manis 0.8kg, Ramulus Cinnamomi 3.5kg, Semen Strychni 3.0kg and Ramulus et Folium Berchemiae Lineatae 2.4kg, be placed in mix homogeneously in jacketed pan, add water and cover powder 2cm, soak 30 minutes, heated and boiled 1h, cooled and filtered, the filtering residue appropriate post-heating that adds water again boils 1h, refilter, twice filtrate is merged, be condensed into extractum, 80 DEG C of dry getting dry extract, dried cream powder was broken into 150 object fine powders, powder gets dry extract again.
The preparation of embodiment 3 Chinese medicine dried cream powders
Take Rhizoma Atractylodis 2.8kg, Herba Ecliptae 2.2kg, Herba Dendrobii 1.6kg, Pseudobulbus Bletillae (Rhizoma Bletillae) 1.1kg, Herba Glechomae 2.0kg, Squama Manis 1.0kg, Ramulus Cinnamomi 2.5kg, Semen Strychni 3.5kg and Ramulus et Folium Berchemiae Lineatae 1.5kg, be placed in mix homogeneously in jacketed pan, add water and cover powder 2cm, soak 30 minutes, heated and boiled 1h, cooled and filtered, the filtering residue appropriate post-heating that adds water again boils 1h, refilter, twice filtrate is merged, be condensed into extractum, 80 DEG C of dry getting dry extract, dried cream powder was broken into 150 object fine powders, powder gets dry extract again.
The effectiveness study of embodiment 4 Chinese medicine dried cream powder external applications to Treatment of knee joint acute traumatic synovitis patient
Treatment of knee joint acute traumatic synovitis patient 29 examples, male's 16 examples, female patient 13 examples, age l7～55 year old, 35.2 years old mean age, course of disease 2h-1d.All patients' damage reason is sprain for exercise, the visible significantly tenderness of patient's knee joint, and floating patella test is positive, and arthrocentesiS is faint yellow or buff liquid, checks without obvious abnormal or slight kneed degenerative change through x-ray.
All patients are accepting after general conventional treatment, adopt Chinese medicine dried cream powder (prepared by the embodiment of the present invention 1) to be modulated into pasty state with Mel, then knee joint are carried out to external application, and 1 time/d, 7d is 1 course for the treatment of, uses continuously 2 courses for the treatment of.After treating two courses for the treatment of, add up therapeutic outcome by following curative effect judging standard: if patient's pain, swelling disappears, and joint motion is normal, can recover normal activity and can think recovery from illness; If pain, swelling disappears substantially, and joint motion obviously improves, and can do some adaptive activities and can think effective; If pain, swelling alleviates, and joint motion makes moderate progress and can think effectively; If but symptom and function of joint do not improve significantly, it is invalid to be considered as.Recovery from illness and effective being considered as are almost recovered, and effectively can be considered improvement.
Therapeutic outcome: through the Chinese medicine dried cream powder external application for curing of 2 courses for the treatment of, the person's of being almost recovered 19 examples in 29 routine Treatment of knee joint acute traumatic synovitis patients, the person's of taking a favorable turn 9 examples, invalid 1 example, total effective rate 96.6%.All patients have no obvious side effect, and curative effect is more remarkable.
Claims (5)
1. a Chinese medicine composition for the treatment of Treatment of knee joint acute traumatic synovitis, is characterized in that: described Chinese medicine composition is prepared from by the traditional Chinese medicinal material raw materials of following weight portion: Rhizoma Atractylodis 21-30 part, Herba Ecliptae 21-30 part, Herba Dendrobii 9-16 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 11-20 part, Herba Glechomae 11-20 part, Squama Manis 5-11 part, Ramulus Cinnamomi 25-37 part, Semen Strychni 25-37 part, Ramulus et Folium Berchemiae Lineatae 15-24 part.
2. the Chinese medicine composition for the treatment of according to claim 1 Treatment of knee joint acute traumatic synovitis, is characterized in that: described Chinese medicine composition is prepared from by the traditional Chinese medicinal material raw materials of following weight portion: Rhizoma Atractylodis 23-27 part, Herba Ecliptae 23-27 part, Herba Dendrobii 11-13 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 13-17 part, Herba Glechomae 13-17 part, Squama Manis 7-9 part, Ramulus Cinnamomi 29-32 part, Semen Strychni 29-32 part, Ramulus et Folium Berchemiae Lineatae 18-20 part.
3. the Chinese medicine composition for the treatment of according to claim 2 Treatment of knee joint acute traumatic synovitis, is characterized in that: described Chinese medicine composition is prepared from by the traditional Chinese medicinal material raw materials of following weight portion: 25 parts of Rhizoma Atractylodis, 25 parts of Herba Ecliptaes, 12 parts of Herba Dendrobiis, 15 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 15 parts of Herba Glechomaes, 8 parts of Squama Manis, 30 parts of Ramulus Cinnamomi, 30 parts of Semen Strychni, 19 parts of Ramulus et Folium Berchemiae Lineataes.
4. according to the Chinese medicine composition for the treatment of Treatment of knee joint acute traumatic synovitis described in claim 1 or 2 or 3, it is characterized in that: described Chinese medicine composition is external preparation, and described external preparation comprises gel, ointment.
5. the application of the Chinese medicine composition described in claim 1 or 2 or 3 in the external used medicine of preparation treatment Treatment of knee joint acute traumatic synovitis.
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| CN201410072781.5A CN103877393B (en) | 2014-03-03 | 2014-03-03 | A kind of Chinese medicine composition and application thereof for the treatment of Treatment of knee joint acute traumatic synovitis |
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| CN201410072781.5A CN103877393B (en) | 2014-03-03 | 2014-03-03 | A kind of Chinese medicine composition and application thereof for the treatment of Treatment of knee joint acute traumatic synovitis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104491703A (en) * | 2014-12-09 | 2015-04-08 | 张爱英 | Oral traditional Chinese medicine composition for treating traumatic synovitis of knee joint |
| CN104587218A (en) * | 2015-02-05 | 2015-05-06 | 闫秀敏 | Traditional Chinese medicine for treating spleen-and-kidney-deficiency type knee joint traumatic synovitis |
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| CN1424024A (en) * | 2001-10-23 | 2003-06-18 | 罗明新 | External used paste for orthopedic diseases |
| CN1947790A (en) * | 2006-05-31 | 2007-04-18 | 胡成章 | Medicine for treating paralysis and its prepn. method |
| CN101085078A (en) * | 2007-06-13 | 2007-12-12 | 毕书平 | Exterior-applied medicine liquid for treating osteoarthrilis |
| CN102327339A (en) * | 2011-09-10 | 2012-01-25 | 杨玉宝 | Traditional Chinese medicine synovium inflammation-removing plaster for treating chronic gonarthromeningitis |
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| CN1424024A (en) * | 2001-10-23 | 2003-06-18 | 罗明新 | External used paste for orthopedic diseases |
| CN1947790A (en) * | 2006-05-31 | 2007-04-18 | 胡成章 | Medicine for treating paralysis and its prepn. method |
| CN101085078A (en) * | 2007-06-13 | 2007-12-12 | 毕书平 | Exterior-applied medicine liquid for treating osteoarthrilis |
| CN102327339A (en) * | 2011-09-10 | 2012-01-25 | 杨玉宝 | Traditional Chinese medicine synovium inflammation-removing plaster for treating chronic gonarthromeningitis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104491703A (en) * | 2014-12-09 | 2015-04-08 | 张爱英 | Oral traditional Chinese medicine composition for treating traumatic synovitis of knee joint |
| CN104587218A (en) * | 2015-02-05 | 2015-05-06 | 闫秀敏 | Traditional Chinese medicine for treating spleen-and-kidney-deficiency type knee joint traumatic synovitis |
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| CN103877393B (en) | 2016-05-11 |
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Inventor after: Yuan Xiaoyan Inventor after: Yu Yan Inventor after: Wang Shengying Inventor after: Lu Haiying Inventor before: Wang Shengying Inventor before: Guo Chuanyou Inventor before: Liu Ying Inventor before: Yuan Xiaoyan |
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