CN103071116B - Traditional Chinese medicine preparation for treating esophagus cancer and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating esophagus cancer and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating esophagus cancer. The traditional Chinese medicine composition mainly comprises pseudo-ginseng, solanum lyratum, hairyvein agrimony, edible tulip, rhizoma bletillae, oldenlandia diffusa, sculellaria barbata, asparagus cochinchinensis, rhizoma dioscoreae, flos sophorae, subprostrate sophora, rhizoma corydalis, bighead atractylodes rhizome, rhizoma curcumae longae and dried alum. The traditional Chinese medicine composition has a remarkable treatment effect for the esophagus cancer and has the effects of relieving pain, stopping bleeding and resisting cancers and tumors; the rhizoma dioscoreae in the prescription has a good opsonization effect for cancer patients subjected to chemoradiotherapy or operative treatment; and most of local common cheap herbs are selected and used, so that the economic burden on the patients is reduced.
Description
Technical field
The invention discloses one and treat esophageal carcinoma Chinese medicine composition, especially treat Chinese medicine composition of cancer and preparation method thereof.Belong to Chinese medicine field.
Background technology
Esophageal carcinoma, is the one of malignant tumor, by controlling the not normal and disease that causes of growth and proliferation of cell mechanism.The feature of cancerous cell be unrestrictedly, hypertrophy without end, the nutrient substance in patient body is consumed in a large number; Cancerous cell discharges multiple toxin, makes human body produce series of symptoms; Cancerous cell also can be transferred to whole body growth and breeding everywhere, cause that human body is become thin, unable, anemia, inappetence, heating and serious organ function impaired etc.And cancer also can disorganize, the 26S Proteasome Structure and Function of organ, causes downright bad hemorrhage concurrent infection, patient is finally dead due to organ failure.Esophageal carcinoma blocks dysphagia of esophagus.
For the treatment of esophageal carcinoma, doctor trained in Western medicine adopts operative treatment, radiotherapy or chemotherapy three one conventionally now, or the method for together treating.Operative treatment: generally include radical surgery, palliative operation, the operation of detecting property.Taking operation as means complete removal of lesions was or cut-out focus, reach the method for curing or controlling cancer.Radiotherapy: being called for short radiotherapy, is to utilize high-energy electromagnetic radiation line to act on life entity, changes biomolecular structure, reaches a kind of Therapeutic Method of destruction of cancer cells object.It is to lonizing radiation sensitivity because of cancerous cell that radiation can be treated cancer.The lonizing radiation of application have x-ray treatment and r line to treat two kinds clinically at present.Chemotherapy: chemotherapy is to take medicine intravascular to whole body, and health all cells is had to impact.This therapy is sometimes also referred to as " born of the same parents poison therapy ", because medicine used is all harmful to, or even with toxicity, and cells in vivo, no matter whether malignant cell, is all damaged.
No matter be adopt operative treatment, radiotherapy or adopt chemotherapy, all patient's health caused to great burden, and costly, sufferer is born painful large.
Summary of the invention
Along with the development of Chinese Chinese medicine, in treatment and control cancer, people have recognized that treatment by Chinese herbs esophageal carcinoma therapeutic process has no side effect gradually, patient bears painful little, and the advantage that cost is saved relatively, for the present situation of existing western medical treatment cancer, one of object of the present invention is to provide a kind of Chinese medicine composition for the treatment of esophagus cancer, there is feature easy to operate, evident in efficacy, and its adopts, and comparatively common Chinese crude drug is as raw material, with low cost in the localities.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat a Chinese medicine composition for esophageal carcinoma, take off the primary raw material of stating weight proportion and be prepared from: Radix Notoginseng 3-9 part, Herba Solani Lyrati 15-30 part, Herba Agrimoniae 10-30 part, Pseudobulbus Cremastrae Seu Pleiones 3-9 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 3-10 part, Herba Hedyotidis Diffusae 15-30 part (preferred, Herba Hedyotidis Diffusae 15.5-29.5 part), Herba Scutellariae Barbatae 15-30 part, Radix Asparagi 10-20 part, Rhizoma Dioscoreae 10-20 part, Flos Sophorae 5-9 part, Radix Sophorae Tonkinensis 3-6 part, Rhizoma Corydalis 3-15 part, Rhizoma Atractylodis Macrocephalae 15-40 part, Rhizoma Curcumae Longae 10-30 part, dried Alumen 10-30 part.
Treat a Chinese medicine composition for esophageal carcinoma, preferred scheme, takes off the primary raw material of stating weight proportion and is prepared from: Radix Notoginseng 5-9 part, Herba Solani Lyrati 16-25 part, Herba Agrimoniae 15-25 part, Pseudobulbus Cremastrae Seu Pleiones 4-8 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 4-8 part, Herba Hedyotidis Diffusae 18-28 part, Herba Scutellariae Barbatae 18-25 part, Radix Asparagi 12-18 part, Rhizoma Dioscoreae 14-18 part, Flos Sophorae 6-8 part, Radix Sophorae Tonkinensis 3.5-5 part, Rhizoma Corydalis 6-14 part, Rhizoma Atractylodis Macrocephalae 20-38 part, Rhizoma Curcumae Longae 15-28 part, dried Alumen 12-28 part.
Treat a Chinese medicine composition for esophageal carcinoma, best scheme, takes off the primary raw material of stating weight proportion and is prepared from: 8 parts of Radix Notoginseng, 20 parts of Herba Solani Lyratis, 20 parts of Herba Agrimoniaes, 6 parts of Pseudobulbus Cremastrae Seu Pleioness, 5 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 parts of Herba Hedyotidis Diffusaes, 20 parts of Herba Scutellariae Barbataes, 15 parts of Radix Asparagis, 15 parts of Rhizoma Dioscoreaes, 7 parts, Flos Sophorae, 4 parts of Radix Sophorae Tonkinensiss, 12 parts of Rhizoma Corydalis, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 25 parts, Rhizoma Curcumae Longae, 15 parts of dried Alumens.
Another object of the present invention is just to provide the preparation method of above-mentioned treatment esophageal carcinoma.
Treat a preparation method for the Chinese medicine composition of esophageal carcinoma, be mainly prepared from by following step:
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, dried Alumen are smashed to the 20-60 minute that is soaked in water, boiled with high heat, change slow fire heating distillation equipment and collect distillate or pass into vapor distillation 30-120 minute, volatile oil and water are together distilled, collect distillate, leave standstill 20-50 minute, distillate is cooled to 20-30 DEG C, after get upper strata fluid, fluid is heated to 100 DEG C-200 DEG C, keep sterilization in 2-8 minute, be cooled to room temperature, after to be distributed into air-tight bottle for subsequent use;
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Pseudobulbus Bletillae (Rhizoma Bletillae) intense fire are fried open, turn 10-20 minute at a simmer, then put into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Rhizoma Dioscoreae, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis and change intense fire and be fried open, rear slow fire is continuous decocts 20-40 minute, leaches medicinal liquid for subsequent use.
Treat a preparation method for the Chinese medicine composition of esophageal carcinoma, preferred, be mainly prepared from by following step:
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, dried Alumen are smashed to the 30-50 minute that is soaked in water, boiled with high heat, change slow fire and add thermal distillation or pass into vapor distillation 40-80 minute, volatile oil and water are together distilled, collect distillate, leave standstill 25-40 minute, distillate is cooled to 25-28 DEG C, after get upper strata fluid, fluid is heated to 120-180 DEG C, keep sterilization in 3-6 minute, be cooled to room temperature, after to be distributed into air-tight bottle for subsequent use;
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Pseudobulbus Bletillae (Rhizoma Bletillae) intense fire are fried open, turn 12-18 minute at a simmer, then put into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Rhizoma Dioscoreae, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis and change intense fire and be fried open, rear slow fire is continuous decocts 25-35 minute, leaches medicinal liquid for subsequent use.
Treat a preparation method for the Chinese medicine composition of esophageal carcinoma, best, be mainly prepared from by following step:
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, dried Alumen are smashed and be soaked in water 35 minutes, boiled with high heat, change slow fire and add thermal distillation or pass into vapor distillation 45 minutes, volatile oil and water are together distilled, collect distillate, leave standstill 30 minutes, distillate is cooled to 26 DEG C, after get upper strata fluid, fluid is heated to 150 DEG C, keep sterilization in 4 minutes, be cooled to room temperature, after to be distributed into air-tight bottle for subsequent use;
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Pseudobulbus Bletillae (Rhizoma Bletillae) intense fire are fried open, turn 15 minutes at a simmer, then put into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Rhizoma Dioscoreae, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis and change intense fire and be fried open, rear slow fire is continuous to be decocted 30 minutes, leaches medicinal liquid for subsequent use.
This Chinese medicine composition is remarkable to esophageal carcinoma effect, not only has effect of pain relieving, hemostasis, also has anticancer antineoplastic action, and Rhizoma Dioscoreae in formula is for the cancer patient through chemotherapy radiotherapy or operative treatment, has good opsonic action.Local common medical material for multiselect of the present invention, cheap, alleviate patient's financial burden.
The pharmacological effect of each crude drug is respectively:
Radix Notoginseng: the property of medicine: sweet in the mouth, micro-hardship, warm in nature.Have styptic powder blood, antiinflammatory, protects the liver, antitumor, and effect of analgesic therapy, for having a delicate constitution and all kinds of mass formed by blood stasis patient.
Herba Solani Lyrati: another name Herba Solani Lyrati, Pennisetum centrasiaticum Tzvel, hair Herba Senecionis Scandentis, hair Radix seu Caulis fici Martinii, Solanum lyratum Thunb., hair Xiucai, calabash grass, gold thread mossback.The property of medicine: bitter in the mouth, property is flat, slightly poisonous.There is removing toxic substances and promoting subsidence of swelling, anticancer effect, for cancer, icterohepatitis.
Herba Agrimoniae: cry again Western Agrimony.Bitter in the mouth, warm in nature.Astringing to arrest bleeding, dysentery relieving, parasite killing.Be widely used in various hemorrhage cards, for example: haematemesis, hematuria, have blood in stool, metrorrhagia, spitting of blood, epistaxis, dysentery, impairment caused by overstrain takes off power, carbuncle, traumatic injury, the cards such as wound hemorrhage, have inhibitory action to cancerous cell, for cancer and various hemorrhage disease.
Pseudobulbus Cremastrae Seu Pleiones: sweet in the mouth, cool in nature.There is heat-clearing and toxic substances removing, eliminating stagnation, antineoplastic effect.
Pseudobulbus Bletillae (Rhizoma Bletillae): call sweet, Bletilla striata (Thunb.ex A.Murray)Rchb.f., gives free of charge, the Pseudobulbus Bletillae (Rhizoma Bletillae), pleionebulbocodioides rolfe, white black youngster's head, Pseudobulbus Bletillae (Rhizoma Bletillae), YANGJIAOQI, Rhizoma Curculiginis, monarch's ball, a pocket palm fibre, Cold boiled chicken, chap mouth medicine, profit are known son.The property of medicine: bitter sweet, be slightly cold, property is puckery.Effect: spasmolytic heresy, blood heresy, dysentery, acute conjunctivitis ， Disorder knot, carbuncle on the back, scrofula, hemorrhoidal hamorrhage, hemorrhoid wart, cutter arrow skin ulcer is flutterred damage, warm malaria, dysentery, sore due to scald and burn, granulation promoting pain relieving, migratory arthralgia.
Herba Hedyotidis Diffusae: another name: Herba Hedyotidis Diffusae, Herba Turczaninowiae Fastigiatae, Radix Picriae felterrae are the dry herb of Maguireothamnus speciosus Herba Hedyotidis Diffusae.The property of medicine: bitter in the mouth, cold nature.There is heat reliving and toxin-eliminating, resolving carbuncle and expulsing boil, detumescence, antitumor, effect of antiinflammatory, for tumors such as acute lymphoblastic type, granulocyte types.
Herba Scutellariae Barbatae: the property of medicine: acrid in the mouth, hardship, cold in nature.There is heat-clearing and toxic substances removing, dissipating blood stasis hemostasis, anticancer effect, for leukemia, gastric cancer, esophageal carcinoma.
Radix Asparagi: the property of medicine: sweet in the mouth, cold in nature, be tonic.Have nourshing Yin and drynsessmoistening prescription, antibacterial, antineoplastic effect, for leukemia, the disease of the deficiency of YIN.
Rhizoma Dioscoreae: the property of medicine: survivor is cool in nature, ripe change cool for temperature.Gui Jing: enter lung, spleen, kidney channel.Effect: spleen invigorating, tonifying the lung, reinforces the kidney, benefit essence.Control diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease, quenches one's thirst, seminal emission, leukorrhagia, frequent micturition.Cure mainly: weakness of the spleen and stomach, the diet of not pursuing progress.
Flos Sophorae: the property of medicine: bitter in the mouth, cold nature.There is hemostasis, pain relieving, antiinflammatory, antiulcer effect, for spitting blood, gastroenteritic ulcer etc.
Radix Sophorae Tonkinensis: the property of medicine: bitter in the mouth, cold in nature.There is removing toxic substances, detumescence, pain relieving, antineoplastic effect is remarkable for malignant tumor effect.
Rhizoma Corydalis: the property of medicine: acrid in the mouth, warm in nature.There is promoting blood circulation to remove blood stasis, promoting the circulation of QI pain relieving, the breast side of body, epigastric pain. amenorrhea dysmenorrhea, postpartum stagnation, effect of tumbling and swelling.
The Rhizoma Atractylodis Macrocephalae: the property of medicine: sweet in the mouth, warm in nature.There is invigorating the spleen and benefiting QI, improve resistance against diseases, antineoplastic effect, for esophageal carcinoma, deficiency of the spleen causing weakness of QI.
Rhizoma Curcumae Longae: the property of medicine: acrid in the mouth, warm in nature.There is circulation of qi promoting, inducing menstruation to relieve menalgia, antitumor, antiinflammatory, effect of blood fat reducing, for lymphatic cancer, the twinge of the breast side of body.
Dried Alumen: another name: Alumen.The property of medicine: sour and astringent, cold.Poisonous.Effect: expectorant, antidiarrheal, hemostasis, removing toxic substances, parasite killing.Cure mainly: hepatitis, jaundice, general edema with yellowish skin, stomach, uterine prolapse, leucorrhea, aphtha of the mouth and tongue.
Chinese medicine composition of the present invention meets Chinese medicine and debates the principle of disease treatment.The medical material of selecting is divided into Orally-administered decoction medicine and the external volatile oil of applying ointment or plaster, and inside and outsidely treats simultaneously, treats more comprehensively, and affected area administration is rapider, and lasting medicine is taken into account inside and outside belonging to, the esophageal carcinoma prescription for the treatment of both the principal and secondary aspects of a disease.Esophageal carcinoma is had to fabulous therapeutical effect, for having fabulous opsonic action because of the long-term thin and weak health of chemicotherapy.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1the Chinese medicine preparation for the treatment of esophageal carcinoma, takes off the primary raw material of stating weight proportion and is prepared from: 3 grams of Radix Notoginseng, 15 grams of Herba Solani Lyratis, 10 grams of Herba Agrimoniaes, 3 grams of Pseudobulbus Cremastrae Seu Pleioness, 3 grams of Pseudobulbus Bletillae (Rhizoma Bletillae), 15 grams of Herba Hedyotidis Diffusaes, 15 grams of Herba Scutellariae Barbataes, 10 grams of Radix Asparagis, 10 grams of Rhizoma Dioscoreaes, 5 grams, Flos Sophorae, 3 grams of Radix Sophorae Tonkinensiss, 3 grams of Rhizoma Corydalis, 15 grams of the Rhizoma Atractylodis Macrocephalaes, 10 grams, Rhizoma Curcumae Longae, 10 grams of dried Alumens.
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, dried Alumen are smashed and be soaked in water 20 minutes, boiled with high heat, change slow fire heating distillation equipment and collect distillate or pass into vapor distillation 30 minutes, volatile oil and water are together distilled, collect distillate, leave standstill 20 minutes, distillate is cooled to 20 DEG C, after get upper strata fluid, fluid is heated to 100 DEG C DEG C, keep sterilization in 2 minutes, be cooled to room temperature, after to be distributed into air-tight bottle for subsequent use.
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Pseudobulbus Bletillae (Rhizoma Bletillae) intense fire are fried open, turn 10 minutes at a simmer, then put into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Rhizoma Dioscoreae, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis and change intense fire and be fried open, rear slow fire is continuous to be decocted 20 minutes, leaches medicinal liquid for subsequent use.
embodiment 2the Chinese medicine preparation for the treatment of esophageal carcinoma, takes off the primary raw material of stating weight proportion and is prepared from: 5 grams of Radix Notoginseng, 16 grams of Herba Solani Lyratis, 15 grams of Herba Agrimoniaes, 4 grams of Pseudobulbus Cremastrae Seu Pleioness, 4 grams of Pseudobulbus Bletillae (Rhizoma Bletillae), 18 grams of Herba Hedyotidis Diffusaes, 18 grams of Herba Scutellariae Barbataes, 12 grams of Radix Asparagis, 14 grams of Rhizoma Dioscoreaes, 6 grams, Flos Sophorae, 3.5 grams of Radix Sophorae Tonkinensiss, 6 grams of Rhizoma Corydalis, 20 grams of the Rhizoma Atractylodis Macrocephalaes, 15 grams, Rhizoma Curcumae Longae, 12 grams of dried Alumens.
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, dried Alumen are smashed and be soaked in water 30 minutes, boiled with high heat, change slow fire and add thermal distillation or pass into vapor distillation 40 minutes, volatile oil and water are together distilled, collect distillate, leave standstill 25 minutes, distillate is cooled to 25 DEG C, after get upper strata fluid, fluid is heated to 120, keep sterilization in 3-6 minute, be cooled to room temperature, after to be distributed into air-tight bottle for subsequent use.
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Pseudobulbus Bletillae (Rhizoma Bletillae) intense fire are fried open, turn 12 minutes at a simmer, then put into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Rhizoma Dioscoreae, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis and change intense fire and be fried open, rear slow fire is continuous to be decocted 25 minutes, leaches medicinal liquid for subsequent use.
embodiment 3the Chinese medicine composition for the treatment of esophageal carcinoma, takes off the primary raw material of stating weight proportion and is prepared from: 9 grams of Radix Notoginseng, 25 grams of Herba Solani Lyratis, 25 grams of Herba Agrimoniaes, 8 grams of Pseudobulbus Cremastrae Seu Pleioness, 8 grams of Pseudobulbus Bletillae (Rhizoma Bletillae), 28 grams of Herba Hedyotidis Diffusaes, 25 grams of Herba Scutellariae Barbataes, 18 grams of Radix Asparagis, 18 grams of Rhizoma Dioscoreaes, 8 grams, Flos Sophorae, 5 grams of Radix Sophorae Tonkinensiss, 14 grams of Rhizoma Corydalis, 38 grams of the Rhizoma Atractylodis Macrocephalaes, 28 grams, Rhizoma Curcumae Longae, 28 grams of dried Alumens.
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, dried Alumen are smashed and be soaked in water 50 minutes, boiled with high heat, change slow fire and add thermal distillation or pass into vapor distillation 80 minutes, volatile oil and water are together distilled, collect distillate, leave standstill 25-40 minute, distillate is cooled to 28 DEG C, after get upper strata fluid, fluid is heated to 180 DEG C, keep sterilization in 6 minutes, be cooled to room temperature, after to be distributed into air-tight bottle for subsequent use.
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Pseudobulbus Bletillae (Rhizoma Bletillae) intense fire are fried open, turn 12-18 minute at a simmer, then put into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Rhizoma Dioscoreae, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis and change intense fire and be fried open, rear slow fire is continuous to be decocted 35 minutes, leaches medicinal liquid for subsequent use.
embodiment 4the Chinese medicine composition for the treatment of esophageal carcinoma, takes off the primary raw material of stating weight proportion and is prepared from: 9 grams of Radix Notoginseng, 30 grams of Herba Solani Lyratis, 30 grams of Herba Agrimoniaes, 9 grams of Pseudobulbus Cremastrae Seu Pleioness, 10 grams of Pseudobulbus Bletillae (Rhizoma Bletillae), 30 grams of Herba Hedyotidis Diffusaes, 30 grams of Herba Scutellariae Barbataes, 20 grams of Radix Asparagis, 20 grams of Rhizoma Dioscoreaes, 9 grams, Flos Sophorae, 6 grams of Radix Sophorae Tonkinensiss, 15 grams of Rhizoma Corydalis, 40 grams of the Rhizoma Atractylodis Macrocephalaes, 30 grams, Rhizoma Curcumae Longae, 30 grams of dried Alumens.
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, Bulbus Allii Cepae are smashed and be soaked in water 60 minutes, boiled with high heat, change slow fire and add thermal distillation or pass into vapor distillation 120 minutes, volatile oil and water are together distilled, collect distillate, leave standstill 50 minutes, distillate is cooled to 30 DEG C, after get upper strata fluid, fluid is heated to 200 DEG C, keep sterilization in 8 minutes, be cooled to room temperature, after to be distributed into air-tight bottle for subsequent use.
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Rhizoma Pinelliae intense fire are fried open, turn 20 minutes at a simmer, then put into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Radix Ophiopogonis, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis and change intense fire and be fried open, rear slow fire is continuous to be decocted 40 minutes, leaching medicinal liquid, is a pair, once a day.
embodiment 5the Chinese medicine composition for the treatment of esophageal carcinoma, takes off the primary raw material of stating weight proportion and is prepared from: 8 grams of Radix Notoginseng, 20 grams of Herba Solani Lyratis, 20 grams of Herba Agrimoniaes, 6 grams of Pseudobulbus Cremastrae Seu Pleioness, 5 grams of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 grams of Herba Hedyotidis Diffusaes, 20 grams of Herba Scutellariae Barbataes, 15 grams of Radix Asparagis, 15 grams of Rhizoma Dioscoreaes, 7 grams, Flos Sophorae, 4 grams of Radix Sophorae Tonkinensiss, 12 grams of Rhizoma Corydalis, 30 grams of the Rhizoma Atractylodis Macrocephalaes, 25 grams, Rhizoma Curcumae Longae, 15 grams of dried Alumens.
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, dried Alumen are smashed and be soaked in water 35 minutes, boiled with high heat, change slow fire and add thermal distillation or pass into vapor distillation 45 minutes, volatile oil and water are together distilled, collect distillate, leave standstill 30 minutes, distillate is cooled to 26 DEG C, after get upper strata fluid, fluid is heated to 150 DEG C, keep sterilization in 4 minutes, be cooled to room temperature, after to be distributed into air-tight bottle for subsequent use.
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Pseudobulbus Bletillae (Rhizoma Bletillae) intense fire are fried open, turn 15 minutes at a simmer, then put into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Rhizoma Dioscoreae, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis and change intense fire and be fried open, rear slow fire is continuous to be decocted 30 minutes, leaches medicinal liquid for subsequent use.
For making the present invention reach optimum therapeuticing effect, Chinese medicine decoction of the present invention, once a day, each pair, volatile oil is applied in the body surface at Ashi point (generally all determine with sick at acupuncture point, and multidigit is around pathological changes), the tsusanli acupoint (two) and position, tumor place, twice of every day.
model case one
Liu xx, man, 39 years old, Meng Jia village, Jin Zhuan town, Sishui County, Jining City in Shandong Province.Symptom: the difficulty of swallowing of eating, weight loss, intermittent pharyngeal pain and hoarseness, with serious vomiting, removing hospital diagnosis is advanced esophageal cancer.Sick age: 10 months.Examine the time: on July 3rd, 2010; Take Chinese medicine decoction of the present invention, once a day, and smear volatile oil in the tsusanli acupoint (two), diaphragm shu cave, every day twice, use traditional Chinese medicine composition for treating of the present invention 10 days, symptoms of emesis alleviates, and pain has very large alleviation; Use traditional Chinese medicine composition for treating of the present invention 3 months, function of deglutition recovers completely, obviously diminishes through examination in hospital tumor.Use traditional Chinese medicine composition for treating of the present invention 10 months, tumor disappears; Use separately volatile oil to consolidate one month, so far without recurrence.
model case two
Solemn xx, man, 68 years old, Liaocheng retired professor.Patient because of carrying out property dysphagia, through the parallel biopsy of boroscopy, is diagnosed as esophageal carcinoma mid-term and row operative treatment in October, 2000.Postoperative patient is abandoned chemicotherapy, and selects this Chinese medicine composition to take orally and external, and adheres to acupoint massage, and appetite, spirit, muscle power are all recovered to some extent.In annual periodic review, it is normal that indices all belongs to.Habit calligraphy, white silk skill in playing chess, singing Qu Jun have achievement, complete recovery of health people's life in person now.
model case three
Korea Spro xx, female, 48 years old, the Su Han village, Pingdu City Lan Di town, Shandong Province.Symptom: just started to swallow pain obstinate, after with the symptom of serious cough, spitting of blood, the obvious enlargement of throat.Be diagnosed as esophageal carcinoma in mid-term through examination in hospital.Sick age: 6 months.Examine the time: on July 22nd, 2010; Take Chinese medicine decoction of the present invention, once a day, and smear the medicine for external use of this Chinese medicine in the tsusanli acupoint (two), diaphragm shu cave, shaoshang acupoint, every day twice, use traditional Chinese medicine composition for treating of the present invention 10 days, spitting of blood symptom alleviates, and esophagus pain is alleviated to some extent; Use traditional Chinese medicine composition for treating of the present invention 2 months, esophageal tumor is dwindled; Use traditional Chinese medicine composition for treating of the present invention 5 months, after hospital's check, find atrophy of tumor, rehabilitation at present.
model case four
The xx of Tang, man, 55 years old, the Tang Cun of Jining City in Shandong Province Zoucheng City.Symptom: on November 29th, 2010 because of bottleneck throat severe pain medical, while examining, esophagus position enlargement on inspection, patient main suit, the difficulty of having a meal, stool blackout, belongs to middle and advanced stage esophageal carcinoma, sick age: 1 year.Examine the time: on March 12nd, 2011; Take Chinese medicine decoction of the present invention, once a day, and in cave, Liangqiu, massage is coated with the medicine for external use of originally wanting, and every day twice, uses traditional Chinese medicine composition for treating of the present invention 20 days, and self-induction esophagus position pain symptom alleviates; Use traditional Chinese medicine composition for treating of the present invention 1 month, feed obviously increases, continue medication to 2011 year August, complexion, than originally there being very large change, is checked through hospital, cancerous cell is without diffusing phenomenon, body weight increases, and there is very large change quality of life during than western medical treatment, and mood is more optimistic than originally, life has been had to new hope, at present rehabilitation.
Specific experiment result is as following table:
Table 1: in order to verify the effect of medicament of the present invention, we have carried out drug study according to embodiment 5 gained Chinese medicines to 240 patients, and accurately data have been carried out to statistics and mathematical analysis.
Specific experiment result is as following table:
Prove through clinical trial, use compared with the means of Chinese medicine composition of the present invention and western medical treatment esophageal carcinoma, control recurrence rate after healing low, treatment means is more comprehensive thoroughly, between the operating period, have no side effect, in treatment esophageal carcinoma, can alleviate the symptom such as pain, inappetence of being brought by esophageal carcinoma.Prove through clinical trial, Chinese drugs agentia effective percentage of the present invention is 96.8%, for early, in and advanced esophageal cancer disease all have good therapeutical effect, most of esophageal cancer patients are in medication about 5 days, pain symptom has obviously and alleviates.For early esophageal cancer patient, adhere to using Chinese medicine composition of the present invention, about ten months, can thoroughly remove focus, middle and terminal cancer patient is using Chinese medicine composition of the present invention about 6 months, can reach the object of controlling or curing cancer, and for patient with advanced cancer, use Chinese medicine composition of the present invention, in effectively controlling cancerous cell high speed diffusion, can make the quality of life that remains life improve, increase the confidence for future life.Therefore Chinese medicine composition of the present invention is a kind of medicine for the treatment of safely and effectively esophagus cancer.
Claims (1)
1. the preparation method of Chinese medicine preparation for the treatment of esophageal carcinoma, is characterized in that, takes off the crude drug of stating weight proportion and is prepared from: 8 grams of Radix Notoginseng, 20 grams of Herba Solani Lyratis, 20 grams of Herba Agrimoniaes, 6 grams of Pseudobulbus Cremastrae Seu Pleioness, 5 grams of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 grams of Herba Hedyotidis Diffusaes, 20 grams of Herba Scutellariae Barbataes, 15 grams of Radix Asparagis, 15 grams of Rhizoma Dioscoreaes, 7 grams, Flos Sophorae, 4 grams of Radix Sophorae Tonkinensiss, 12 grams of Rhizoma Corydalis, 30 grams of the Rhizoma Atractylodis Macrocephalaes, 25 grams, Rhizoma Curcumae Longae, 15 grams of dried Alumens, step is as follows:
1. the Rhizoma Atractylodis Macrocephalae, Rhizoma Curcumae Longae, dried Alumen are smashed and be soaked in water 35 minutes, boiled with high heat, change slow fire and add thermal distillation or pass into vapor distillation 45 minutes, volatile oil and water are together distilled, collect distillate, leave standstill 30 minutes, distillate is cooled to 26 DEG C, after get upper strata fluid, fluid is heated to 150 DEG C, keep sterilization in 4 minutes, be cooled to room temperature, after to be distributed into air-tight bottle be the external volatile oil of applying ointment or plaster;
2. Herba Solani Lyrati, Pseudobulbus Cremastrae Seu Pleiones and Pseudobulbus Bletillae (Rhizoma Bletillae) intense fire are fried open, turn 15 minutes at a simmer, then put into Radix Notoginseng, Herba Agrimoniae, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Asparagi, Rhizoma Dioscoreae, Flos Sophorae, Radix Sophorae Tonkinensis and Rhizoma Corydalis and change intense fire and be fried open, rear slow fire is continuous to be decocted 30 minutes, and leaching medicinal liquid is Orally-administered decoction medicine.
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| CN104800585A (en) * | 2015-05-14 | 2015-07-29 | 奉化科创科技服务有限公司 | Traditional Chinese medicine for treating esophageal cancer |
| CN104971316A (en) * | 2015-07-22 | 2015-10-14 | 赵洪礼 | Composition for treating esophageal cancer and preparation method thereof |
| CN104998110A (en) * | 2015-07-24 | 2015-10-28 | 卢德国 | Traditional Chinese medicine for treating phlegm-damp internal obstructing type esophageal cancer and preparation method thereof |
| CN105998760A (en) * | 2016-04-29 | 2016-10-12 | 吕彦丽 | Medicine for treating esophagus cancer |
| CN106860768A (en) * | 2017-04-13 | 2017-06-20 | 河南中医药大学 | A kind of Chinese medicine compound prescription for treating the cancer of the esophagus |
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