CN105796951A - External-use preparation used by radiology department for treating nasal polyp and preparation method - Google Patents
External-use preparation used by radiology department for treating nasal polyp and preparation method Download PDFInfo
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- CN105796951A CN105796951A CN201610175256.5A CN201610175256A CN105796951A CN 105796951 A CN105796951 A CN 105796951A CN 201610175256 A CN201610175256 A CN 201610175256A CN 105796951 A CN105796951 A CN 105796951A
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Abstract
The invention discloses an external-use preparation used by a radiology department for treating nasal polyp and a preparation method.The preparation is prepared from, by weight, 7-14 parts of fructus corni, 5-10 parts of whiteflower cacalia seeds, 3-7 parts of roots and rhizomes of ripqrian greenbrier, 6-11 parts of roots of apricotleaf ladybell, 5-9 parts of common lophatherum herbs, 3-7 parts of flos carthami, 4-8 parts of black bamboo, 6-11 parts of javan waterdropwort herbs, 5-11 parts of roots of beautiful sweetgum, 3-8 parts of arabian jasmine flowers, 4-9 parts of spica prunellae, 5-10 parts of mongolian snakegourd roots and 3-6 parts of rush-like bulrush herbs.The external-use preparation is free of side effect, cannot generate drug resistance and dependence and is short in treatment course and quick in effectiveness, and the disease is not prone to relapse.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of for treating polypous external preparation and preparation method.
Background technology
Nasal polyp, otorhinolaryngology disease, betide the vegetation of nasal cavity.The traditional Chinese medical science claims nasal polyp.Nasal polyp many because of usually addicted to
Eat and pungent process savoury, accumulate raw damp and hot；On steam in lung, tie stagnant nose key；Or wind-heat evil toxin invasion and attack lung meridian, lung qi must not be declared freely, long-pending
Caused by poly-nose key.Having one or more vegetation, smooth surface in mainly showing as nose key, color is light white or light red, and that touches is soft
Soft and the most bitterly, have a stuffy nose with persistence, hyposmia, nasal mucus increases, headache, dizzy etc..Treatment: section's medicine within the least polyp
Treatment is main.2. Drug therapy nonresponder row functional scope nasal surgery.The most multiple or recurrent polyp row is conventional
Operative treatment.
Application publication number CN 104815284 A(application number 201510139268.8) Chinese patent literature disclose one
Kind treat polypous Chinese medicine composition, the weight portion of its constitutive material is: Rhizoma Chuanxiong 4-6, Herba Menthae 10-12, Radix Platycodonis 8-10,
Radix Astragali 5-7, Flos Lonicerae 18-20, Radix Curcumae 4-6, Radix Notoginseng 2-4, Poria 1-3, Radix Bupleuri 8-10, Fructus Xanthii 5-6, Bombyx Batryticatus 2-4, goose
BUSHICAO 6-8, Radix Tripterygii Wilfordii 4-6, Cortex Lycii 2-4, Radix Angelicae Dahuricae 1-3, Rhizoma Acori Graminei 6-8, Rhizoma Curcumae 3-5, Radix Panacis Quinquefolii 2-4, five times
Sub-5-6, Radix Puerariae 3-4, Folium Eupatorii 2-4, Radix Pottsiae Laxiflorae 1-3 and Ramulus et folium berchemiae floribundae 2-4.Application publication number CN 105168694 A
The Chinese patent literature of (application number 201510639439.3) discloses one and treats polypous Chinese medicine composition, by following former
Material is made: Herba Moslae, Herba Coriandri, Fructus Arctii, Periostracum Cicadae, Herba Spirodelae, Radix Trichosanthis, Spica Prunellae, Cortex Dictamni, Natrii Sulfas, Radix Cynanchi Paniculati, Semen Phaseoli, long-pending
Snow grass, Flos Chrysanthemi Indici, Tremella, Herba Centipedae, Radix Polygalae, Rhizoma Acori Graminei.Application publication number CN 104606631 A(application number
201510001541.0) Chinese patent literature discloses one and treats nasal polyp Chinese medicine formula, Chinese medicine used in its formula
Raw material and weight is: Herba Xanthii 42 grams, Herba Menthae 26 grams, Herba Eupatorii 19 grams, Ganoderma 32 grams, Fructus Forsythiae 23 grams, 18 grams of Poria, Fructus Lycii 31
Gram, Radix Asparagi 21 grams, Flos Lonicerae 29 grams, the Radix Angelicae Dahuricae 33 grams, the Radix Paeoniae Alba 17 grams, Radix Et Caulis Acanthopanacis Senticosi 42 grams, Radix Curcumae 29 grams, Folium Aconiti Kusnezoffii 34 grams, bear
Caulis Lonicerae 53 grams, Semen Juglandis 176 grams, 60 grams of Ovum Gallus domesticus album and Mel 45 grams.
At present, the polypous medicine of clinical treatment mostly is Western medicine and Chinese patent medicine, and Western medicine side effect is big, should not use for a long time, for a long time
Use and easily develop immunity to drugs.Treat polypous Chinese medicine preparation on market of a great variety, but great majority also exist take effect slow,
The course for the treatment of length, the shortcoming such as easy recurrence, bring bigger misery and inconvenience to patient.
Summary of the invention
For the deficiencies in the prior art, it is an object of the invention to provide a kind of for treating polypous external preparation and system
Method.The present invention has no side effect, and will not develop immunity to drugs and dependency, short treating period, instant effect, is difficult to recurrence.
The technical scheme is that
For treating polypous external preparation, take off and state the primary raw material medicine of weight proportion and be prepared from: Fructus Corni 7-14, bitter
Semen Nelumbinis 5-10, Radix et Rhizoma Smilacis Ripariae 3-7, shepherd's purse 6-11, Herba Lophatheri 5-9, Flos Carthami 3-7, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 4-8, Herba Oenanthes Javanicae 6-11, Radix Liquidambaris 5-
11, Flos Jasmini Sambac 3-8, Spica Prunellae 4-9, Radix Trichosanthis 5-10, Herba scirpi juncoidis 3-6.
For treating polypous external preparation, preferred scheme is, takes off and states the primary raw material medicine of weight proportion and prepare
Form: Fructus Corni 9-12, Semen Caesalpiniae Minacis 7-9, Radix et Rhizoma Smilacis Ripariae 4-6, shepherd's purse 8-10, Herba Lophatheri 6-8, Flos Carthami 4-6, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 5-7, Herba Oenanthes Javanicae
7-10, Radix Liquidambaris 7-10, Flos Jasmini Sambac 5-7, Spica Prunellae 5-8, Radix Trichosanthis 6-8, Herba scirpi juncoidis 4-5.
For treating polypous external preparation, scheme more preferably is, takes off the primary raw material medicine stating weight proportion
It is prepared from: Fructus Corni 11, Semen Caesalpiniae Minacis 8, Radix et Rhizoma Smilacis Ripariae 5, shepherd's purse 9, Herba Lophatheri 7, Flos Carthami 5, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 6, Herba Oenanthes Javanicae 9, Radix Liquidambaris
8, Flos Jasmini Sambac 6, Spica Prunellae 7, Radix Trichosanthis 7, Herba scirpi juncoidis 4.5.
The above-mentioned preparation method for treating polypous external preparation is:
(1) taking Semen Caesalpiniae Minacis and put into the edible oil cauldron cooked, the amount of edible oil is 1.8-2.6 times of Semen Caesalpiniae Minacis weight, and slow fire explodes
16-25 minute, leaching medicine oil, medicinal residues are dried；
(2) take Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and Radix Trichosanthis to be placed in pot, stir-fry 15-22 minute with slow fire, be spilled into and be watered vinegar,
The amount being watered vinegar is Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and the 1/8-1/3 of Radix Trichosanthis gross weight, and water is 1 with the volume ratio of vinegar:
1, stir-fry limit, limit is spilt, and continues to fry 12 minutes, takes out, dry；
(3) by remaining the 8 taste crude drug in addition to Semen Caesalpiniae Minacis, Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and Radix Trichosanthis and step (1) gained medicine
Slag and step (2) gained are put in pot, boiling twice, add the water of 8 taste crude drug gross weights 5.3-6.8 times, often every time
Secondary decoction 1.2 hours, merges twice medicinal liquid；
(4) step (1) gained medicine oil and step (3) gained medicinal liquid are mixed, with the rotating speed centrifugation 18 points of 4500r/min
Clock, takes upper liquid, is condensed into the thick paste that relative density is 1.4-1.44, sterile packaged, to obtain final product.
Preferably being in step (1), the amount of edible oil is 2-2.5 times of Semen Caesalpiniae Minacis weight.
Preferably it is that in step (1), slow fire explodes 18-23 minute.
Preferably it is in step (2), stir-fries 17-21 minute with slow fire.
Preferably being in step (2), the amount being watered vinegar is Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and the 1/ of Radix Trichosanthis gross weight
7-1/5。
Preferably it is in step (3), adds the water of 8 taste crude drug gross weights 5.7-6.6 times every time.
Preferably it is in step (4), is condensed into the thick paste that relative density is 1.41-1.43.
More preferably, in step (1) amount is Semen Caesalpiniae Minacis weight 2.3 times of edible oil.
More preferably, in step (1), slow fire explodes 21 minutes.
More preferably, step (2) stir-fries 19 minutes with slow fire.
More preferably, the amount being watered vinegar in step (2) is Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and Radix Trichosanthis gross weight
1/6。
More preferably, step (3) adds the water of 8 taste crude drug gross weight 6.4 times every time.
More preferably, step (4) is condensed into the thick paste that relative density is 1.42.
What the present invention provided is used for treating polypous external preparation scientific formula, and preparation method is simple, easy to use.Remove
Outside this, the excellent results of the present invention is also manifested by:
1, the present invention has no side effect, and will not develop immunity to drugs and dependency；
2, short treating period, instant effect, is difficult to recurrence；
3, there is effect of liver and kidney tonifying, moistening the lung and resolving the phlegm, clearing away heat and eliminating dampness, mass dissipating and swelling eliminating, moistening the lung and resolving phlegm, expelling phlegm for arresting cough, for controlling
Treatment nasal polyp is evident in efficacy.
Detailed description of the invention
Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.
Embodiment 1 is used for treating polypous external preparation, and the primary raw material medicine taking following weight parts is prepared from (every part
For 480g): Fructus Corni 7 parts, Semen Caesalpiniae Minacis 5 parts, Radix et Rhizoma Smilacis Ripariae 3 parts, shepherd's purse 6 parts, Herba Lophatheri 5 parts, 3 parts of Flos Carthami, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 4 parts, water
Celery 6 parts, Radix Liquidambaris 5 parts, Flos Jasmini Sambac 3 parts, Spica Prunellae 4 parts, Radix Trichosanthis 5 parts, Herba scirpi juncoidis 3 parts.
The above-mentioned preparation method for treating polypous external preparation is:
(1) taking Semen Caesalpiniae Minacis and put into the edible oil cauldron cooked, the amount of edible oil is 1.8 times of Semen Caesalpiniae Minacis weight, and slow fire explodes 16 points
Clock, leaches medicine oil, and medicinal residues are dried；
(2) take Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and Radix Trichosanthis to be placed in pot, stir-fry 15 minutes with slow fire, be spilled into and be watered vinegar, convert
The amount of water vinegar is Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and the 1/8 of Radix Trichosanthis gross weight, and water is 1:1 with the volume ratio of vinegar, and limit is fried
While spill, continue to fry 12 minutes, take out, dry；
(3) by remaining the 8 taste crude drug in addition to Semen Caesalpiniae Minacis, Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and Radix Trichosanthis and step (1) gained medicine
Slag and step (2) gained are put in pot, boiling twice, add the water of 8 taste crude drug gross weight 5.3 times every time, decoct every time
Boil 1.2 hours, merge twice medicinal liquid；
(4) step (1) gained medicine oil and step (3) gained medicinal liquid are mixed, with the rotating speed centrifugation 18 points of 4500r/min
Clock, takes upper liquid, is condensed into the thick paste that relative density is 1.4, sterile packaged, to obtain final product.
Gained of the present invention for treating the using method of polypous external preparation is: after cleaning nasal cavity, by institute of the present invention
Obtain product and be applied directly to nasal cavity affected part, smear 2 every day.
Embodiment 2 is used for treating polypous external preparation, and the primary raw material medicine taking following weight parts is prepared from (every part
For 480g): Fructus Corni 14 parts, Semen Caesalpiniae Minacis 10 parts, Radix et Rhizoma Smilacis Ripariae 7 parts, shepherd's purse 11 parts, Herba Lophatheri 9 parts, 7 parts of Flos Carthami, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 8 parts,
Herba Oenanthes Javanicae 11 parts, Radix Liquidambaris 11 parts, Flos Jasmini Sambac 8 parts, Spica Prunellae 9 parts, Radix Trichosanthis 10 parts, Herba scirpi juncoidis 6 parts.
The above-mentioned preparation method for treating polypous external preparation is:
(1) taking Semen Caesalpiniae Minacis and put into the edible oil cauldron cooked, the amount of edible oil is 2.6 times of Semen Caesalpiniae Minacis weight, and slow fire explodes 25 points
Clock, leaches medicine oil, and medicinal residues are dried；
(2) take Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and Radix Trichosanthis to be placed in pot, stir-fry 22 minutes with slow fire, be spilled into and be watered vinegar, convert
The amount of water vinegar is Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and the 1/3 of Radix Trichosanthis gross weight, and water is 1:1 with the volume ratio of vinegar, and limit is fried
While spill, continue to fry 12 minutes, take out, dry；
(3) by remaining the 8 taste crude drug in addition to Semen Caesalpiniae Minacis, Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and Radix Trichosanthis and step (1) gained medicine
Slag and step (2) gained are put in pot, boiling twice, add the water of 8 taste crude drug gross weight 6.8 times every time, decoct every time
Boil 1.2 hours, merge twice medicinal liquid；
(4) step (1) gained medicine oil and step (3) gained medicinal liquid are mixed, with the rotating speed centrifugation 18 points of 4500r/min
Clock, takes upper liquid, is condensed into the thick paste that relative density is 1.44, sterile packaged, to obtain final product.
Model case one: Zhao XX, man, 29 years old.Before more than 1 year, there are the symptoms such as nasal obstruction, rhinorrhea, giddy, headache in patient,
Check suffer from nasal polyp at local hospital.Taking multiple Chinese and western drugs, effect does not shows.The present embodiment gained is used to be used for controlling
Treat polypous external preparation, after cleaning nasal cavity, the present embodiment products obtained therefrom is applied directly to nasal cavity affected part, smears 2 every day
Secondary.After treatment two weeks, symptom, sign are wholly absent, and nasal sinuses CT examination is normal.Follow up a case by regular visits to without recurrence.
Embodiment 3 is used for treating polypous external preparation, takes the primary raw material medicine of following weight parts and is prepared from that (every part is
480g): Fructus Corni 9 parts, Semen Caesalpiniae Minacis 7 parts, Radix et Rhizoma Smilacis Ripariae 4 parts, shepherd's purse 8 parts, Herba Lophatheri 6 parts, 4 parts of Flos Carthami, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 5 parts, Herba Oenanthes Javanicae 7
Part, Radix Liquidambaris 7 parts, Flos Jasmini Sambac 5 parts, Spica Prunellae 5 parts, Radix Trichosanthis 6 parts, Herba scirpi juncoidis 4 parts.
The above-mentioned preparation method for treating polypous external preparation is:
(1) taking Semen Caesalpiniae Minacis and put into the edible oil cauldron cooked, the amount of edible oil is 2 times of Semen Caesalpiniae Minacis weight, and slow fire explodes 18 minutes,
Leaching medicine oil, medicinal residues are dried；
(2) take Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and Radix Trichosanthis to be placed in pot, stir-fry 17 minutes with slow fire, be spilled into and be watered vinegar, convert
The amount of water vinegar is Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and the 1/5 of Radix Trichosanthis gross weight, and water is 1:1 with the volume ratio of vinegar, and limit is fried
While spill, continue to fry 12 minutes, take out, dry；
(3) by remaining the 8 taste crude drug in addition to Semen Caesalpiniae Minacis, Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and Radix Trichosanthis and step (1) gained medicine
Slag and step (2) gained are put in pot, boiling twice, add the water of 8 taste crude drug gross weight 5.7 times every time, decoct every time
Boil 1.2 hours, merge twice medicinal liquid；
(4) step (1) gained medicine oil and step (3) gained medicinal liquid are mixed, with the rotating speed centrifugation 18 points of 4500r/min
Clock, takes upper liquid, is condensed into the thick paste that relative density is 1.41, sterile packaged, to obtain final product.
Model case two: Xue XX, female, 55 years old.Before more than 4 years, there are the symptoms such as nasal obstruction, watery nasal discharge viscous, hyposmia in vain in patient,
Examine as nasal polyp to examination in hospital.Taking multiple Chinese and western drugs, effect does not shows.Under the introduction of friend, my institute's diagnosis and treatment of coming.
Patient's nasal obstruction, watery nasal discharge viscous, hyposmia in vain, nose heave dusk are vexed, abundant expectoration uncomfortable in chest.Polyp color is in vain such as fat, and light water skiing is bright；Pale tongue with white fur
Greasy, moderate pulse is sliding.The present embodiment gained is used to be used for treating polypous external preparation, after cleaning nasal cavity, by the present embodiment gained
Product is applied directly to nasal cavity affected part, smears 2 every day.After treatment two weeks, symptom, sign are wholly absent, nasal sinuses CT examination
Normally.Follow up a case by regular visits to without recurrence.
Embodiment 4 is used for treating polypous external preparation, and the primary raw material medicine taking following weight parts is prepared from (every part
For 480g): Fructus Corni 12 parts, Semen Caesalpiniae Minacis 9 parts, Radix et Rhizoma Smilacis Ripariae 6 parts, shepherd's purse 10 parts, Herba Lophatheri 8 parts, 6 parts of Flos Carthami, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 7 parts,
Herba Oenanthes Javanicae 10 parts, Radix Liquidambaris 10 parts, Flos Jasmini Sambac 7 parts, Spica Prunellae 8 parts, Radix Trichosanthis 8 parts, Herba scirpi juncoidis 5 parts.
The above-mentioned preparation method for treating polypous external preparation is:
(1) taking Semen Caesalpiniae Minacis and put into the edible oil cauldron cooked, the amount of edible oil is 2.5 times of Semen Caesalpiniae Minacis weight, and slow fire explodes 23 points
Clock, leaches medicine oil, and medicinal residues are dried；
(2) take Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and Radix Trichosanthis to be placed in pot, stir-fry 21 minutes with slow fire, be spilled into and be watered vinegar, convert
The amount of water vinegar is Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and the 1/5 of Radix Trichosanthis gross weight, and water is 1:1 with the volume ratio of vinegar, and limit is fried
While spill, continue to fry 12 minutes, take out, dry；
(3) by remaining the 8 taste crude drug in addition to Semen Caesalpiniae Minacis, Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and Radix Trichosanthis and step (1) gained medicine
Slag and step (2) gained are put in pot, boiling twice, add the water of 8 taste crude drug gross weight 6.6 times every time, decoct every time
Boil 1.2 hours, merge twice medicinal liquid；
(4) step (1) gained medicine oil and step (3) gained medicinal liquid are mixed, with the rotating speed centrifugation 18 points of 4500r/min
Clock, takes upper liquid, is condensed into the thick paste that relative density is 1.43, sterile packaged, to obtain final product.
Model case three: Liu XX, man, 22 years old.Before more than 2 years, patient occurs that Progressive symmetric erythrokeratodermia bilateral is had a stuffy nose, with rhinorrhea, head
Bitterly, the symptom such as tinnitus.Bilateral nasal polyp is diagnosed at local hospital.Taking multiple Chinese and western medical thing, effect does not shows.Use this reality
Execute example gained for treating polypous external preparation, after cleaning nasal cavity, the present embodiment products obtained therefrom is applied directly to nasal cavity
Affected part, smears 2 every day.After treatment two weeks, symptom, sign are wholly absent, and nasal sinuses CT examination is normal.Follow up a case by regular visits to without recurrence.
Embodiment 5 is used for treating polypous external preparation, and the primary raw material medicine taking following weight parts is prepared from (every part
For 480g): Fructus Corni 11 parts, Semen Caesalpiniae Minacis 8 parts, Radix et Rhizoma Smilacis Ripariae 5 parts, shepherd's purse 9 parts, Herba Lophatheri 7 parts, 5 parts of Flos Carthami, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 6 parts, water
Celery 9 parts, Radix Liquidambaris 8 parts, Flos Jasmini Sambac 6 parts, Spica Prunellae 7 parts, Radix Trichosanthis 7 parts, Herba scirpi juncoidis 4.5 parts.
The above-mentioned preparation method for treating polypous external preparation is:
(1) taking Semen Caesalpiniae Minacis and put into the edible oil cauldron cooked, the amount of edible oil is 2.3 times of Semen Caesalpiniae Minacis weight, and slow fire explodes 21 points
Clock, leaches medicine oil, and medicinal residues are dried；
(2) take Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and Radix Trichosanthis to be placed in pot, stir-fry 19 minutes with slow fire, be spilled into and be watered vinegar, convert
The amount of water vinegar is Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and the 1/6 of Radix Trichosanthis gross weight, and water is 1:1 with the volume ratio of vinegar, and limit is fried
While spill, continue to fry 12 minutes, take out, dry；
(3) by remaining the 8 taste crude drug in addition to Semen Caesalpiniae Minacis, Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and Radix Trichosanthis and step (1) gained medicine
Slag and step (2) gained are put in pot, boiling twice, add the water of 8 taste crude drug gross weight 6.4 times every time, decoct every time
Boil 1.2 hours, merge twice medicinal liquid；
(4) step (1) gained medicine oil and step (3) gained medicinal liquid are mixed, with the rotating speed centrifugation 18 points of 4500r/min
Clock, takes upper liquid, is condensed into the thick paste that relative density is 1.42, sterile packaged, to obtain final product.
Used by the present invention, the pharmacology of main raw material of Chinese medicine is as follows:
Fructus Corni: base: for the sarcocarp of Cornaceae plant Fructus Corni.The property of medicine: sour, puckery, tepor.Return liver, kidney channel.Function master
Control: liver and kidney tonifying, essence astringing and desertion stemming.For vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating is empty
De-, interior-heat is quenched one's thirst.
Semen Caesalpiniae Minacis: base: for the seed of leguminous plant beak pod Semen Caesalpiniae.The property of medicine: bitter；Cool cold；Nontoxic.GUIXIN；Spleen；Kidney channel.
Function cures mainly: clearing away heat and eliminating dampness, eliminating stasis to stop pain.Main anemopyretic cold, dysentery stranguria with turbid discharge, hiccup, carbuncle, skin ulcer tinea, traumatic injury, poisonous snake stings
Wound.
Radix et Rhizoma Smilacis Ripariae: base: for the root and rhizome of liliaceous plant Radix et Rhizoma Smilacis Ripariae.The property of medicine: sweet；Bitter；Flat.Return liver, lung meridian.Function
Cure mainly: wind-damp dispelling；The meridian dredging；Expelling phlegm for arresting cough.Main air arthralgia chiefly caused by damp pathogen is demonstrate,proved；Impairment caused by overstrain lumbago；Traumatic injury；Cough and asthma.
Shepherd's purse: base: for Campanulaceae shepherd's purse, the root of slender lobule shepherd's purse.The property of medicine: sweet in the mouth；Cold in nature.Return lung；Spleen channel.Merit
With curing mainly: moistening the lung and resolving the phlegm；Heat-clearing and toxic substances removing.Main xeropulmonary cough；Laryngopharynx swelling and pain；Quench one's thirst；Furuncle ulcerative carbuncle poison；Drug intoxication.
Herba Lophatheri: base: for grass Herba Lophatheri or the herb of China Herba Lophatheri.The property of medicine: sweet；Light；Cold.Function master
Control: heat clearing away；Relieving restlessness；Diuresis.Main dysphoria with smothery sensation is thirsty, aphtha of the mouth and tongue, gingival swelling and pain, children's's night crying due to fright in infant, hot urination, stranguria with turbid discharge.
Flos Carthami: base: for the dry flower of feverfew Flos Carthami.The property of medicine: pungent, temperature.GUIXIN, Liver Channel.Function cures mainly: invigorate blood circulation logical
Warp, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, abdominal mass mass in the abdomen, traumatic injury, skin infection swells and ache.
Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle: base: the spire do not put for the volume of grass family Phyllostachys plant phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle etc..The property of medicine: hardship sweet, micro-, light,
Cold.GUIXIN, Liver Channel.Function cures mainly: clear away heart-fire relieving restlessness, diuresis, removing toxic substances.Cure mainly that calentura is tired becomes soaked with sweat, oliguria with reddish urine, burn and scald.
Herba Oenanthes Javanicae: base: the root of Umbelliferae Herba Apii platymiscium Herba Oenanthes Javanicae and herb.The property of medicine: sweet, flat.Function cures mainly: heat clearing away profit
Wet, hemostasis, blood pressure lowering.For cold, fever, vomiting and diarrhoea, urinary tract infection, metrorrhagia, leucorrhea, hypertension.
Radix Liquidambaris: base: for the tree root of Hamamelidaceae Plants sweetgum.The property of medicine: Quanzhou book on Chinese herbal medicine ": " pungent, bitter, property is put down, nothing
Poison." " Quanzhou book on Chinese herbal medicine ": " enter spleen, kidney, liver three warp." function cures mainly: control carbuncle, furuncle, rheumatic arthritis.
Flos Jasmini Sambac: base: for the flower of Oleaceae plants jasmine.The property of medicine: pungent, micro-sweet, warm in nature.Return spleen, stomach, Liver Channel.Function
Cure mainly: regulating QI to relieve pain, ward off dirty dissipating depression of QI.Hindering in main wet method, chest and diaphragm does not relaxes；Dysentery is suffered from abdominal pain；Dizziness headache；Conjunctival congestion；Sore.
Spica Prunellae: base: for the dry fruit ear of labiate Spica Prunellae.The property of medicine: pungent, bitter, cold.Return liver, gallbladder meridian.Merit
With curing mainly: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, mesh pearl nyctalgia, dizziness of having a headache, scrofula, goiter, acute mastitis swells and ache,
Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Radix Trichosanthis: base: for cucurbitaceous plant Fructus Trichosanthis and the root of China's Fructus Trichosanthis.The property of medicine: sweet in the mouth, micro-hardship, cold nature.Return
Lung, stomach warp.Function cures mainly: clearing away heat and promoting production of body fluid, moistening the lung and resolving phlegm, detumescence and apocenosis.Main calentura is thirsty, polydipsia of quenching one's thirst, lung-heat type cough, skin infection
Toxic swelling.
Herba scirpi juncoidis: base: the herb of Cyperaceae firefly Lin.The property of medicine: sweet, light, cool.Function cures mainly: heat-clearing and toxic substances removing, removing heat from blood profit
Water.Cure mainly pulmonary tuberculosis hemoptysis, acute toothache, conjunctival congestion and swelling pain, urinary tract infection.
Test example 1 gained of the present invention is used for treating the clinical practice of polypous external preparation (embodiment 5): 2012 10
In May ,-2014 moon, screen 340 example Nasal Polyps Patients in 3 hospitals.Being randomly divided into two groups, experimental group and matched group (often organize 170
Example).Between two groups of patients, the aspect such as sex, age, the cause of disease and the course of disease compares, no significant difference (P ＞ 0.05), tool
There is comparability.
Therapeutic Method: experimental group takes gained of the present invention for treating polypous external preparation, and using method is: cleaning
After nasal cavity, products obtained therefrom of the present invention is applied directly to nasal cavity affected part, smears 2 every day.Matched group uses glucocorticoid, resists
The Drug therapys such as raw element, antifungal agent, antihistaminic.Within 5 days, it is a course for the treatment of, after treating 3 courses for the treatment of, carries out comparitive study.
Curative effect situation criterion: cure: cure: symptom, sign are wholly absent, and nasal sinuses CT examination is normal；Take a turn for the better: nasal cavity
Pus tears significantly reduce, and have mild nasal congestion, concha nasalis inferior hyperemia swelling substantially to disappear, and nasal meatus has a small amount of glutinous pus tears, nasal sinuses CT examination, with
Comparing before treatment, sinus cavities increase in density shadow scope is obviously reduced；Invalid: symptom, sign are substantially without improving.Total effectively including cures
And improvement, result is as shown in table 1.
Table 1: gained of the present invention is used for treating polypous external preparation compliance test result
Efficacy analysis: as it can be seen from table 1 experimental group cures 148 examples, cure rate 87.06%, take a turn for the better 19 examples, improvement rate
11.18%, invalid 3 examples, inefficiency 1.76%, total effective rate 98.24%；Matched group cures 83 examples, cure rate 48.82%, improvement 41
Example, improvement rate 24.12%, invalid 46 examples, inefficiency 27.06%, total effective rate 72.94%.The cure rate of experimental group and total effective rate
Apparently higher than matched group.Test shows, the clinical efficacy of experimental group is substantially better than matched group, significant difference (P ＜ 0.05), has
Statistical significance.
The present invention, with Fructus Corni, Semen Caesalpiniae Minacis, Radix et Rhizoma Smilacis Ripariae and shepherd's purse etc. for primary raw material medicine, makes for treating polypous
External preparation.Fructus Corni liver and kidney tonifying in side, essence astringing and desertion stemming.Semen Caesalpiniae Minacis clearing away heat and eliminating dampness, eliminating stasis to stop pain.Radix et Rhizoma Smilacis Ripariae wind-damp dispelling；Logical
Meridians；Expelling phlegm for arresting cough.Shepherd's purse moistening the lung and resolving the phlegm；Heat-clearing and toxic substances removing.Herba Lophatheri heat clearing away；Relieving restlessness；Diuresis.Flos Carthami promoting blood circulation to restore menstrual flow, dissipating blood stasis is only
Bitterly.Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle clears away heart-fire relieving restlessness, diuresis, removing toxic substances.Herba Oenanthes Javanicae clearing away heat-damp and promoting diuresis, hemostasis, blood pressure lowering.Flos Jasmini Sambac regulating QI to relieve pain, wards off dirty dissipating depression of QI.
Spica Prunellae relieves inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.Radix Trichosanthis clearing away heat and promoting production of body fluid, moistening the lung and resolving phlegm, detumescence and apocenosis.Herba scirpi juncoidis heat-clearing and toxic substances removing,
Removing heat from blood diuretic.Many medicines share, mutually coordinated, play altogether liver and kidney tonifying, moistening the lung and resolving the phlegm, clearing away heat and eliminating dampness, mass dissipating and swelling eliminating, moistening the lung and resolving phlegm,
The effect of expelling phlegm for arresting cough, evident in efficacy for treatment nasal polyp.
Finally it should be noted that embodiment is the optimum detailed description of the invention of the present invention, be not limited to this
Invention, although being described in detail the present invention with reference to previous embodiment, for a person skilled in the art, it depends on
So the technical scheme described in foregoing embodiments can be modified, or wherein portion of techniques feature is carried out equivalent replace
Change.All within the spirit and principles in the present invention, any modification, equivalent substitution and improvement etc. made, should be included in the present invention
Protection domain within.
Claims (10)
1. it is used for treating polypous external preparation, it is characterised in that take off and state the primary raw material medicine of weight proportion and be prepared from:
Fructus Corni 7-14, Semen Caesalpiniae Minacis 5-10, Radix et Rhizoma Smilacis Ripariae 3-7, shepherd's purse 6-11, Herba Lophatheri 5-9, Flos Carthami 3-7, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 4-8, Herba Oenanthes Javanicae 6-
11, Radix Liquidambaris 5-11, Flos Jasmini Sambac 3-8, Spica Prunellae 4-9, Radix Trichosanthis 5-10, Herba scirpi juncoidis 3-6.
It is used for the most as claimed in claim 1 treating polypous external preparation, it is characterised in that take off the master stating weight proportion
Crude drug is wanted to be prepared from: Fructus Corni 9-12, Semen Caesalpiniae Minacis 7-9, Radix et Rhizoma Smilacis Ripariae 4-6, shepherd's purse 8-10, Herba Lophatheri 6-8, Flos Carthami 4-6, bamboo
Volume heart 5-7, Herba Oenanthes Javanicae 7-10, Radix Liquidambaris 7-10, Flos Jasmini Sambac 5-7, Spica Prunellae 5-8, Radix Trichosanthis 6-8, Herba scirpi juncoidis 4-5.
It is used for the most as claimed in claim 1 treating polypous external preparation, it is characterised in that take off the master stating weight proportion
Crude drug is wanted to be prepared from: Fructus Corni 11, Semen Caesalpiniae Minacis 8, Radix et Rhizoma Smilacis Ripariae 5, shepherd's purse 9, Herba Lophatheri 7, Flos Carthami 5, Phyllostachys nigra (Lodd.) Munrovar.henonis(Mitf.) Stapfex Rendle 6, Herba Oenanthes Javanicae 9,
Radix Liquidambaris 8, Flos Jasmini Sambac 6, Spica Prunellae 7, Radix Trichosanthis 7, Herba scirpi juncoidis 4.5.
4. the preparation method for treating polypous external preparation as described in claims 1 to 3 is arbitrary, it is characterised in that
Step is as follows:
(1) taking Semen Caesalpiniae Minacis and put into the edible oil cauldron cooked, the amount of edible oil is 1.8-2.6 times of Semen Caesalpiniae Minacis weight, and slow fire explodes
16-25 minute, leaching medicine oil, medicinal residues are dried；
(2) take Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and Radix Trichosanthis to be placed in pot, stir-fry 15-22 minute with slow fire, be spilled into and be watered vinegar,
The amount being watered vinegar is Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and the 1/8-1/4 of Radix Trichosanthis gross weight, and water is 1 with the volume ratio of vinegar:
1, stir-fry limit, limit is spilt, and continues to fry 12 minutes, takes out, dry；
(3) by remaining the 8 taste crude drug in addition to Semen Caesalpiniae Minacis, Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and Radix Trichosanthis and step (1) gained medicine
Slag and step (2) gained are put in pot, boiling twice, add the water of 8 taste crude drug gross weights 5.3-6.8 times, often every time
Secondary decoction 1.2 hours, merges twice medicinal liquid；
(4) step (1) gained medicine oil and step (3) gained medicinal liquid are mixed, with the rotating speed centrifugation 18 points of 4500r/min
Clock, takes upper liquid, is condensed into the thick paste that relative density is 1.4-1.44, sterile packaged, to obtain final product.
5. the preparation method for treating polypous external preparation as claimed in claim 4, it is characterised in that step (1)
The amount of edible oil is 2-2.5 times (the preferably amount of edible oil is 2.3 times of Semen Caesalpiniae Minacis weight) of Semen Caesalpiniae Minacis weight.
6. the preparation method for treating polypous external preparation as claimed in claim 4, it is characterised in that step (1)
Slow fire explodes 18-23 minute (preferably slow fire explodes 21 minutes).
7. the preparation method for treating polypous external preparation as claimed in claim 4, it is characterised in that step (2)
17-21 minute (preferably stir-frying 19 minutes) is stir-fried with slow fire with slow fire.
8. the preparation method for treating polypous external preparation as claimed in claim 4, it is characterised in that step (2)
Being watered the 1/7-1/5(that amount is Fructus Corni, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and Radix Trichosanthis gross weight of vinegar and being preferably watered the amount of vinegar is mountain
The Fructus Evodiae, Radix et Rhizoma Smilacis Ripariae, shepherd's purse and the 1/6 of Radix Trichosanthis gross weight).
9. the preparation method for treating polypous external preparation as claimed in claim 4, it is characterised in that step (3)
Add the water (the most every time adding the water of 8 taste crude drug gross weight 6.4 times) of 8 taste crude drug gross weights 5.7-6.6 times every time.
10. the preparation method for treating polypous external preparation as claimed in claim 4, it is characterised in that step (4)
It is condensed into the thick paste (being preferably condensed into the thick paste that relative density is 1.42) that relative density is 1.41-1.43.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106039135A (en) * | 2016-08-13 | 2016-10-26 | 华梅 | Traditional Chinese medicine composition for treating nasal polyp, and preparation method thereof |
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| CN106039135A (en) * | 2016-08-13 | 2016-10-26 | 华梅 | Traditional Chinese medicine composition for treating nasal polyp, and preparation method thereof |
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