CN104324091A - Traditional Chinese medicine formula for treating rectal cancer - Google Patents
Traditional Chinese medicine formula for treating rectal cancer Download PDFInfo
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- CN104324091A CN104324091A CN201410627817.1A CN201410627817A CN104324091A CN 104324091 A CN104324091 A CN 104324091A CN 201410627817 A CN201410627817 A CN 201410627817A CN 104324091 A CN104324091 A CN 104324091A
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- 208000015634 Rectal Neoplasms Diseases 0.000 title claims abstract description 32
- 239000003814 drug Substances 0.000 title claims abstract description 30
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Classifications
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Abstract
The invention relates to a traditional Chinese medicine formula for treating rectal cancer, belonging to the field of traditional Chinese medicines. The traditional Chinese medicine formula is prepared from the following components in parts by weight: 10-20 parts of Chinese sage herb, 10-20 parts of long-noded pit viper, 10-20 parts of cynanchum otophyllum schneid, 10-14 parts of panax notoginseng, 5-15 parts of centipede, 4-8 parts of honeysuckle stem and 5-15 parts of rheum officinale. The medicine composition has efficacy of reinforcing qi, nourishing blood, promoting blood circulation, removing blood stasis, clearing away heat and toxic materials and resisting cancers and is capable of effectively treating the rectal cancer and strengthening appetite of a patient and immunity.
Description
[technical field]
The present invention relates to technical field of Chinese medicine, particularly a kind of Chinese medicine formula for the treatment of rectal cancer.
[technical background]
At present in the field of Chinese medicines for the treatment of rectal cancer, there is the weak point of two aspects: one is that therapeutic effect is obvious not, two be take effect slower.So that large quantities of rectal cancer patient or can not with the growth for the treatment of Chinese medicine Tumor suppression, or tumor recurrence, transfer, diffusion after excision, patient and family members thereof are unsatisfied with this.
For problem set forth above, the invention provides a kind of Chinese medicine for the treatment of rectal cancer, it can effectively solve in the past in rectum cancer treatment effect obvious not, take effect slower problem, the present invention is effective, instant effect, has the advantage of Be very effective, determined curative effect.
[summary of the invention]
The object of the present invention is to provide a kind of Chinese medicine formula effectively can treating rectal cancer, provided by the present invention be treatment rectal cancer Chinese medicine formula can invigorating the spleen and benefiting QI, YIN nourishing is logical falls.Rectal cancer can be treated preferably, have no side effect, safe and reliable.
Technical scheme of the present invention is as follows:
Treat a Chinese medicine formula for rectal cancer, it is characterized in that: the active ingredient of described pharmaceutical composition is prepared from by following raw material:
Herba Salviae Chinensis, Agkistrodon, Radix Astagali, Radix Notoginseng, Scolopendra, vine of Flos Lonicerae, Radix Et Rhizoma Rhei.
Further, the active ingredient of preferred described pharmaceutical composition is prepared from by the raw material of following weight portion:
Herba Salviae Chinensis 10 parts-20 parts, Agkistrodon 10 parts-20 parts, Radix Astagali 10 parts-20 parts,
Radix Notoginseng 10 parts-14 parts, Scolopendra 5 parts-15 parts, vine of Flos Lonicerae 4 parts-8 parts, Radix Et Rhizoma Rhei 5 parts-15 parts.
Further, the active ingredient of preferred described pharmaceutical composition is prepared from by the raw material of following weight portion:
Herba Salviae Chinensis 15 parts, Agkistrodon 15 parts, Radix Astagali 15 parts,
Radix Notoginseng 12 parts, Scolopendra 10 parts, vine of Flos Lonicerae 6 parts, Radix Et Rhizoma Rhei 10 parts.
The dosage form of above-mentioned arbitrary pharmaceutical composition is preferably oral liquid, granule, capsule or tablet.
The preparation method of above-mentioned arbitrary pharmaceutical composition, is characterized in that, gets Herba Salviae Chinensis, Agkistrodon, Radix Astagali, Radix Notoginseng, Scolopendra, vine of Flos Lonicerae and Radix Et Rhizoma Rhei by weight ratio, add water 4-5 doubly by gross weight, and temperature fire decocts 2-3 hour, collecting decoction after decocting twice, filter, make oral liquid.
The preparation method of above-mentioned arbitrary pharmaceutical composition, is characterized in that, gets Herba Salviae Chinensis, Agkistrodon, Radix Astagali, Radix Notoginseng, Scolopendra, vine of Flos Lonicerae and Radix Et Rhizoma Rhei by weight ratio, add water 4-5 doubly by gross weight, temperature fire decocts 2-3 hour, and collecting decoction after decocting twice filters; Be concentrated into the paste that relative density is 1.32-1.40, then dry, pulverize into fine powder below 80 degree, add adjuvant, mixing, makes granule.
The preparation method of above-mentioned arbitrary pharmaceutical composition, is characterized in that, gets Herba Salviae Chinensis, Agkistrodon, Radix Astagali, Radix Notoginseng, Scolopendra, vine of Flos Lonicerae and Radix Et Rhizoma Rhei by weight ratio, add water 4-5 doubly by gross weight, temperature fire decocts 2-3 hour, and collecting decoction after decocting twice filters; Be concentrated into the paste that relative density is 1.32-1.40, then dry, pulverize into fine powder below 80 degree, add adjuvant, mixing, makes tablet.
The raw material of Chinese medicine medicine details adopted in the present invention is as follows:
Herba Salviae Chinensis, removing blood stasis, circulation of qi promoting, removing food stagnancy, pain relieving.Zhi lumps in the chest and abdomen, coagulation of QI-blood, trusted subordinate's pain, the lower swollen pain of the side of body, amenorrhea, postnatal blood stasis is suffered from abdominal pain, and traumatic injury, skin ulcer swells hard.
Agkistrodon, sweet in the mouth, cold in nature.Return stomach, lung, large intestine, urinary bladder channel, heat-clearing and toxic substances removing, eliminating carbuncle is loose straight, promoting urination to remove dampness.
Radix Astagali, invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Radix Notoginseng, cures mainly spitting of blood, and spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, and breast ventral spine pain, tumbling down swells and ache.
Scolopendra, has activating QI to eliminate phlegm, preventing or arresting vomiting relieving distension, the liver soothing and the spleen invigorating, the multiple medicinal function of stomach function regulating.
Vine of Flos Lonicerae, has regulating qi-flowing for strengthening spleen, and in tune, dampness, reduces phlegm.Cure mainly distension and fullness in the abdomen or pain, the dyspepsia of stagnation of QI in spleen and stomach.The cough and asthma of the abdominal distention uncomfortable in chest in turbid damp resistance, indigestion and loss of appetite loose stool, phlegm-damp heap soil or fertilizer over and around the roots lung.
Radix Et Rhizoma Rhei, dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.
The present invention adopts above technical scheme, compared with prior art, has the following advantages: effect that pharmaceutical composition tool benefiting QI and nourishing blood of the present invention, blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing are anticancer, effectively can treat rectal cancer, strengthens patient's appetite, enhancing immunity.
Directly close detailed description of the invention to be below described further technical scheme of the present invention.
[detailed description of the invention]
Embodiment 1
Treat a Chinese medicine formula for rectal cancer, be made up of (every part of 1g) according to weight classification following component:
Herba Salviae Chinensis 10 parts, Agkistrodon 10 parts of Radix Astagali 10 parts, three
27 10 parts, Scolopendra 5 parts of vine of Flos Lonicerae 4 parts, Radix Et Rhizoma Rhei 5 parts.
After above weight classification composition, add water 4-5 doubly by gross weight, temperature fire decocts 2-3 hour, and collecting decoction after decocting twice filters, adds adjuvant, make oral liquid.
Embodiment 2
Treat a Chinese medicine formula for rectal cancer, be made up of (every part of 1g) according to weight classification following component:
Herba Salviae Chinensis 15 parts, Agkistrodon 15 parts, Radix Astagali 15 parts, Radix Notoginseng 12 parts, Scolopendra 10 parts, vine of Flos Lonicerae 6 parts, Radix Et Rhizoma Rhei 10 parts.
After above weight classification composition, add water 4-5 doubly by gross weight, temperature fire decocts 2-3 hour, and collecting decoction after decocting twice filters, be concentrated into the paste that relative density is 1.32-1.40, below 80 degree, dry, pulverize into fine powder again, add adjuvant (starch oar 10%, dextrin 10%, lactose 5%, dry starch 5%, stearic acid 2%, mannitol 1%, Talcum acid 2%), mixing, makes capsule.
Embodiment 3
Treat a Chinese medicine formula for rectal cancer, be made up of (every part of 1g) according to weight classification following component:
Herba Salviae Chinensis 20 parts, Agkistrodon 20 parts, Radix Astagali 20 parts, Radix Notoginseng 14 parts, Scolopendra 15 parts, vine of Flos Lonicerae 8 parts, Radix Et Rhizoma Rhei 15 parts.
After above weight classification composition, add water 4-5 doubly by gross weight, temperature fire decocts 2-3 hour, and collecting decoction after decocting twice filters, be concentrated into the paste that relative density is 1.32-1.40, below 80 degree, dry, pulverize into fine powder again, add adjuvant (starch oar 10%, dextrin 10%, lactose 5%, dry starch 5%, stearic acid 2%, magnesium stearate 1%, Talcum acid 2%), mixing, makes granule.
Above three embodiment gained medicines are used for rectal cancer clinical trial, and use efficacy assessment standard is:
1, effective: body constitution strengthens, limbs are strong, and digestion and defecation etc. are uncomfortable obviously to be alleviated, and CT examination rectum region tumors tumor body reduces, and other position does not find nascent tumor.
2, effective: body constitution strengthens, the discomforts such as digestion and defecation have alleviation, and CT examination rectal neoplasm tumor body has no increase, and other position has no nascent tumor.
3, worsen: disease is unchanged, and rectal neoplasm tumor body increases to some extent, or other position finds nascent tumor.
The 80 routine rectal cancer patients that year March in February, 2012 to 2014 seeks medical advice, man 43 example, female 37 example, age 20-85 year, the course of disease 3 months to 3 years.
This test is provided with 3 test group altogether, and each test group random assortment patient treats.Test group 1 use-case 1 gained Drug therapy, test group 2 uses the Drug therapy of embodiment 2 gained, and test group 3 uses the Drug therapy of embodiment 3 gained, if 20 examples are matched group, matched group adopts western medicine treatment, and total effective rate is 50%.
The straight fruit obtained is as following table:
| Test group | Number of cases | Effectively | Effective | Worsen | Effective percentage (%) |
| Test group 1 | 20 | 17 | 2 | 1 | 85％ |
| Test group 2 | 20 | 16 | 4 | 0 | 80％ |
| Test group 3 | 20 | 17 | 4 | 0 | 85％ |
| Matched group | 20 | 10 | 6 | 4 | 50％ |
From above data analysis, can draw the medicine of gained of the present invention treatment rectal cancer, total effective rate reaches more than 80%, safe and reliable, have no side effect, and embodiment 3 is preferred plan, and effective percentage can reach 85%.
Although for reaching illustration purpose, the above is the preferred embodiments of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme that foregoing embodiments is recorded, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. treat a Chinese medicine formula for rectal cancer, it is characterized in that, the active ingredient of described pharmaceutical composition is prepared from by following raw material: Herba Salviae Chinensis, Agkistrodon, Radix Astagali, Radix Notoginseng, Scolopendra, vine of Flos Lonicerae, Radix Et Rhizoma Rhei.
2. treat the Chinese medicine formula of rectal cancer for one kind, it is characterized in that, the active ingredient of described pharmaceutical composition is prepared from by the raw material of following weight portion: Herba Salviae Chinensis 10 parts-20 parts, Agkistrodon 10 parts-20 parts, Radix Astagali 10 parts-20 parts, Radix Notoginseng 10 parts-14 parts, Scolopendra 5 parts-15 parts, vine of Flos Lonicerae 4 parts-8 parts, Radix Et Rhizoma Rhei 5 parts-15 parts.
3. treat the Chinese medicine formula of rectal cancer as claimed in claim 1, it is characterized in that, the active ingredient of described pharmaceutical composition is prepared from by the raw material of following weight portion: Herba Salviae Chinensis 10 parts, Agkistrodon 10 parts, Radix Astagali 10 parts, Radix Notoginseng 10 parts, Scolopendra 5 parts, vine of Flos Lonicerae 4 parts, Radix Et Rhizoma Rhei 5 parts.
4. treat the Chinese medicine formula of rectal cancer as claimed in claim 1, it is characterized in that, the active ingredient of described pharmaceutical composition is prepared from by the raw material of following weight portion: Herba Salviae Chinensis 15 parts, Agkistrodon 15 parts, Radix Astagali 15 parts, Radix Notoginseng 12 parts, Scolopendra 10 parts, vine of Flos Lonicerae 6 parts, Radix Et Rhizoma Rhei 10 parts.
5. treat the Chinese medicine formula of rectal cancer for one kind, it is characterized in that, the active ingredient of described pharmaceutical composition is prepared from by the raw material of following weight portion: Herba Salviae Chinensis 20 parts, Agkistrodon 20 parts, Radix Astagali 20 parts, Radix Notoginseng 14 parts, Scolopendra 15 parts, vine of Flos Lonicerae 8 parts, Radix Et Rhizoma Rhei 15 parts.
6. the Chinese medicine formula for the treatment of rectal cancer as claimed in claim 1, it is characterized in that, the dosage form of described pharmaceutical composition is oral liquid, granule, capsule or tablet.
7. the Chinese medicine formula for the treatment of rectal cancer as claimed in claim 1, it is characterized in that, get Herba Salviae Chinensis, Agkistrodon, Radix Astagali, Radix Notoginseng, Scolopendra, vine of Flos Lonicerae and Radix Et Rhizoma Rhei by weight ratio, add water 4-5 doubly by gross weight, temperature fire decocts 2-3 hour, collecting decoction after decocting twice, filters, makes oral liquid.
8. the Chinese medicine formula for the treatment of rectal cancer as claimed in claim 1, is characterized in that, get Herba Salviae Chinensis, Agkistrodon, Radix Astagali, Radix Notoginseng, Scolopendra, vine of Flos Lonicerae and Radix Et Rhizoma Rhei by weight ratio, add water 4-5 doubly by gross weight, temperature fire decocts 2-3 hour, and collecting decoction after decocting twice filters, be concentrated into the paste that relative density is 1.32-1.40, below 80 degree, dry, pulverize into fine powder again, add adjuvant, mixing, makes granule.
9. the Chinese medicine formula for the treatment of rectal cancer as claimed in claim 1, is characterized in that, get Herba Salviae Chinensis, Agkistrodon, Radix Astagali, Radix Notoginseng, Scolopendra, vine of Flos Lonicerae and Radix Et Rhizoma Rhei by weight ratio, add water 4-5 doubly by gross weight, temperature fire decocts 2-3 hour, and collecting decoction after decocting twice filters, be concentrated into the paste that relative density is 1.32-1.40, below 80 degree, dry, pulverize into fine powder again, add adjuvant, mixing, makes tablet.
10. the Chinese medicine formula for the treatment of rectal cancer as claimed in claim 1 or 2 or 3 or 4, is characterized in that, get Herba Salviae Chinensis, Agkistrodon, Radix Astagali, Radix Notoginseng, Scolopendra, vine of Flos Lonicerae and Radix Et Rhizoma Rhei by weight ratio, add water 4-5 doubly by gross weight, temperature fire decocts 2-3 hour, and collecting decoction after decocting twice filters, be concentrated into the paste that relative density is 1.32-1.40, below 80 degree, dry, pulverize into fine powder again, add adjuvant, mixing, makes capsule.
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