CN1240701C - 用作5HT2C激动剂的2,3,4,4a－四氢－1H－吡嗪并(1,2－a)喹喔啉－5(6H)酮衍生物 - Google Patents

用作5HT2C激动剂的2,3,4,4a－四氢－1H－吡嗪并(1,2－a)喹喔啉－5(6H)酮衍生物 Download PDF

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Publication number
CN1240701C
CN1240701C CNB998144169A CN99814416A CN1240701C CN 1240701 C CN1240701 C CN 1240701C CN B998144169 A CNB998144169 A CN B998144169A CN 99814416 A CN99814416 A CN 99814416A CN 1240701 C CN1240701 C CN 1240701C
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China
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hydrogen
compound
pyrazine
quinoxaline
chloro
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Expired - Fee Related
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CNB998144169A
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English (en)
Chinese (zh)
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CN1330652A (zh
Inventor
A·L·萨布
G·S·维尔马克
J·A·纳尔逊
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Wyeth LLC
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Wyeth LLC
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CNB998144169A 1998-12-17 1999-12-16 用作5HT2C激动剂的2,3,4,4a－四氢－1H－吡嗪并(1,2－a)喹喔啉－5(6H)酮衍生物 Expired - Fee Related CN1240701C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21347198A 1998-12-17 1998-12-17
US09/213,471 1998-12-17

Publications (2)

Publication Number Publication Date
CN1330652A CN1330652A (zh) 2002-01-09
CN1240701C true CN1240701C (zh) 2006-02-08

Family

ID=22795247

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998144169A Expired - Fee Related CN1240701C (zh) 1998-12-17 1999-12-16 用作5HT2C激动剂的2,3,4,4a－四氢－1H－吡嗪并(1,2－a)喹喔啉－5(6H)酮衍生物

Country Status (18)

Country Link
EP (1) EP1140940A1 (ru)
JP (1) JP2002532504A (ru)
KR (1) KR20010108025A (ru)
CN (1) CN1240701C (ru)
AR (1) AR022687A1 (ru)
AU (1) AU3123400A (ru)
BR (1) BR9916326A (ru)
CA (1) CA2351385A1 (ru)
CZ (1) CZ20012193A3 (ru)
EA (1) EA200100671A1 (ru)
HU (1) HUP0104773A3 (ru)
IL (1) IL143323A0 (ru)
NO (1) NO20013001D0 (ru)
NZ (1) NZ512765A (ru)
PL (1) PL348815A1 (ru)
SK (1) SK8192001A3 (ru)
WO (1) WO2000035922A1 (ru)
ZA (1) ZA200104598B (ru)

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Also Published As

Publication number Publication date
CZ20012193A3 (cs) 2001-12-12
SK8192001A3 (en) 2001-12-03
PL348815A1 (en) 2002-06-17
EA200100671A1 (ru) 2001-12-24
AU3123400A (en) 2000-07-03
HUP0104773A2 (hu) 2002-04-29
EP1140940A1 (en) 2001-10-10
JP2002532504A (ja) 2002-10-02
WO2000035922A1 (en) 2000-06-22
AR022687A1 (es) 2002-09-04
IL143323A0 (en) 2002-04-21
CN1330652A (zh) 2002-01-09
KR20010108025A (ko) 2001-12-07
NZ512765A (en) 2003-10-31
NO20013001L (no) 2001-06-15
BR9916326A (pt) 2001-10-02
HUP0104773A3 (en) 2004-10-28
NO20013001D0 (no) 2001-06-15
CA2351385A1 (en) 2000-06-22
ZA200104598B (en) 2002-09-05

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