CN1201003C - 脂肪细胞特异性蛋白质同系物 - Google Patents

脂肪细胞特异性蛋白质同系物 Download PDF

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Publication number
CN1201003C
CN1201003C CNB988089114A CN98808911A CN1201003C CN 1201003 C CN1201003 C CN 1201003C CN B988089114 A CNB988089114 A CN B988089114A CN 98808911 A CN98808911 A CN 98808911A CN 1201003 C CN1201003 C CN 1201003C
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CN
China
Prior art keywords
polypeptide
seq
sequence
gly
residue
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Expired - Fee Related
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CNB988089114A
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English (en)
Chinese (zh)
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CN1272883A (zh
Inventor
P·O·施帕德
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Zymogenetics Inc
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Zymogenetics Inc
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Publication of CN1272883A publication Critical patent/CN1272883A/zh
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Publication of CN1201003C publication Critical patent/CN1201003C/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CNB988089114A 1997-07-18 1998-07-17 脂肪细胞特异性蛋白质同系物 Expired - Fee Related CN1201003C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5315497P 1997-07-18 1997-07-18
US60/053,154 1997-07-18

Publications (2)

Publication Number Publication Date
CN1272883A CN1272883A (zh) 2000-11-08
CN1201003C true CN1201003C (zh) 2005-05-11

Family

ID=21982287

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB988089114A Expired - Fee Related CN1201003C (zh) 1997-07-18 1998-07-17 脂肪细胞特异性蛋白质同系物

Country Status (18)

Country Link
US (2) US6265544B1 (enExample)
EP (1) EP1002075B1 (enExample)
JP (1) JP3762220B2 (enExample)
KR (1) KR100385868B1 (enExample)
CN (1) CN1201003C (enExample)
AT (1) ATE327328T1 (enExample)
AU (1) AU743745B2 (enExample)
BR (1) BR9810917A (enExample)
CA (1) CA2296530A1 (enExample)
DE (1) DE69834643T2 (enExample)
DK (1) DK1002075T3 (enExample)
ES (1) ES2264207T3 (enExample)
HU (1) HUP0003762A3 (enExample)
IL (1) IL134011A0 (enExample)
NO (1) NO20000215L (enExample)
PL (1) PL338139A1 (enExample)
RU (1) RU2218402C2 (enExample)
WO (1) WO1999004000A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP1002075B1 (en) * 1997-07-18 2006-05-24 ZymoGenetics, Inc. Adipocyte-specific protein homologs
US6566499B1 (en) * 1997-07-18 2003-05-20 Zymogenetics, Inc. Adipocyte-specific protein homologs
FR2767135B1 (fr) * 1997-08-06 2002-07-12 Genset Sa Recepteur complexe lsr, activite, clonage, et application au diagnostic, a la prevention et/ou au traitement de d'obesite et des risques ou complications associes
US20030129691A1 (en) * 1998-02-09 2003-07-10 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7300774B1 (en) * 1999-12-09 2007-11-27 The Regents Of The University Of California Multimeric fusion proteins of the TNF superfamily ligands
US6544946B1 (en) * 1999-02-19 2003-04-08 Zymogenetics, Inc. Inhibitors for use in hemostasis and immune function
US20040014650A1 (en) * 2002-07-17 2004-01-22 Sheppard Paul D Methods for enhancing wound repair
HK1039892A1 (zh) * 1999-02-19 2002-05-17 Zymogenetics, Inc. 止血和免疫功能的抑制剂
US20050042719A1 (en) * 1999-05-27 2005-02-24 Zymogenetics, Inc. Adipocyte complement related protein homolog zacrp5
AU5037100A (en) * 1999-05-27 2000-12-18 Zymogenetics Inc. Adipocyte complement related protein homolog zacrp6
WO2000073444A1 (en) * 1999-05-27 2000-12-07 Zymogenetics, Inc. Adipocyte complement related protein homolog zacrp5
EP1953173B1 (en) * 1999-06-15 2009-11-18 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids endoding the same
WO2001002565A2 (en) * 1999-07-01 2001-01-11 Zymogenetics, Inc. Secreted protein zacrp4
DE19963859A1 (de) * 1999-12-30 2001-07-12 Apotech Res & Dev Ltd Bi- oder Oligomer eines Di-, Tri-, Quattro- oder Pentamers von rekombinanten Fusionsproteinen
AU2001297656A1 (en) * 2000-11-29 2002-09-19 Zymogenetics, Inc. Adipocyte complement related protein zacrp11
US7348406B2 (en) 2001-01-16 2008-03-25 Serono Genetics Institute S.A. Metabolic gene polynucleotides and polypeptides and uses thereof
US7326678B2 (en) 2001-01-16 2008-02-05 Serono Genetics Institute S.A. GMG-3 GMG-4 and GMG-6 polynucleotides and polypeptides and uses thereof
CA2478675A1 (en) * 2002-03-08 2003-09-18 Zymogenetics, Inc. Inhibitors for use in hemostasis
EP1756159A1 (en) * 2004-05-21 2007-02-28 Xencor, Inc. C1q family member proteins with altered immunogenicity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2153480A1 (en) 1993-11-12 1995-06-01 Kenichi Matsubara Gene signature
US5869330A (en) 1995-06-05 1999-02-09 Whitehead Institute For Biomedical Research DNA encoding a novel serum protein produced exclusively in adipocytes
EP1002075B1 (en) * 1997-07-18 2006-05-24 ZymoGenetics, Inc. Adipocyte-specific protein homologs
NZ522634A (en) * 1997-12-03 2004-02-27 Genentech Inc PRO243 encoding a polypeptide with homology to chordin and antibodies and vectors

Also Published As

Publication number Publication date
EP1002075B1 (en) 2006-05-24
BR9810917A (pt) 2000-08-15
RU2218402C2 (ru) 2003-12-10
HUP0003762A3 (en) 2005-11-28
DE69834643T2 (de) 2007-05-10
HUP0003762A2 (hu) 2001-08-28
JP3762220B2 (ja) 2006-04-05
KR100385868B1 (ko) 2003-06-02
KR20010021973A (ko) 2001-03-15
NO20000215D0 (no) 2000-01-17
EP1002075A1 (en) 2000-05-24
IL134011A0 (en) 2001-04-30
WO1999004000A1 (en) 1999-01-28
JP2001510045A (ja) 2001-07-31
NO20000215L (no) 2000-03-17
US20020156243A1 (en) 2002-10-24
AU8411398A (en) 1999-02-10
AU743745B2 (en) 2002-02-07
ES2264207T3 (es) 2006-12-16
US6265544B1 (en) 2001-07-24
PL338139A1 (en) 2000-09-25
CA2296530A1 (en) 1999-01-28
ATE327328T1 (de) 2006-06-15
DE69834643D1 (de) 2006-06-29
CN1272883A (zh) 2000-11-08
DK1002075T3 (da) 2006-09-18
US6518403B2 (en) 2003-02-11

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