CA2296530A1 - Adipocyte-specific protein homologs - Google Patents
Adipocyte-specific protein homologs Download PDFInfo
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- CA2296530A1 CA2296530A1 CA002296530A CA2296530A CA2296530A1 CA 2296530 A1 CA2296530 A1 CA 2296530A1 CA 002296530 A CA002296530 A CA 002296530A CA 2296530 A CA2296530 A CA 2296530A CA 2296530 A1 CA2296530 A1 CA 2296530A1
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- 230000003830 regulated secretory pathway Effects 0.000 description 1
- 238000010405 reoxidation reaction Methods 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000004007 reversed phase HPLC Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 239000002336 ribonucleotide Substances 0.000 description 1
- 125000002652 ribonucleotide group Chemical group 0.000 description 1
- 238000002805 secondary assay Methods 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 239000011669 selenium Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 108010048818 seryl-histidine Proteins 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 230000037432 silent mutation Effects 0.000 description 1
- 210000001013 sinoatrial node Anatomy 0.000 description 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 description 1
- AWUCVROLDVIAJX-GSVOUGTGSA-N sn-glycerol 3-phosphate Chemical compound OC[C@@H](O)COP(O)(O)=O AWUCVROLDVIAJX-GSVOUGTGSA-N 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000000527 sonication Methods 0.000 description 1
- 230000009870 specific binding Effects 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 108010018381 streptavidin-binding peptide Proteins 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 description 1
- 230000002889 sympathetic effect Effects 0.000 description 1
- 210000002820 sympathetic nervous system Anatomy 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 230000028016 temperature homeostasis Effects 0.000 description 1
- NPDBDJFLKKQMCM-UHFFFAOYSA-N tert-butylglycine Chemical compound CC(C)(C)C(N)C(O)=O NPDBDJFLKKQMCM-UHFFFAOYSA-N 0.000 description 1
- 229960000814 tetanus toxoid Drugs 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 229960004072 thrombin Drugs 0.000 description 1
- 229940113082 thymine Drugs 0.000 description 1
- 210000001541 thymus gland Anatomy 0.000 description 1
- 238000011830 transgenic mouse model Methods 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 102000003390 tumor necrosis factor Human genes 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 108010003137 tyrosyltyrosine Proteins 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 229940035893 uracil Drugs 0.000 description 1
- 229940116269 uric acid Drugs 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 108010015385 valyl-prolyl-proline Proteins 0.000 description 1
- 108010009962 valyltyrosine Proteins 0.000 description 1
- 210000003556 vascular endothelial cell Anatomy 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5315497P | 1997-07-18 | 1997-07-18 | |
| US60/053,154 | 1997-07-18 | ||
| PCT/US1998/014864 WO1999004000A1 (en) | 1997-07-18 | 1998-07-17 | Adipocyte-specific protein homologs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2296530A1 true CA2296530A1 (en) | 1999-01-28 |
Family
ID=21982287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002296530A Abandoned CA2296530A1 (en) | 1997-07-18 | 1998-07-17 | Adipocyte-specific protein homologs |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US6265544B1 (enExample) |
| EP (1) | EP1002075B1 (enExample) |
| JP (1) | JP3762220B2 (enExample) |
| KR (1) | KR100385868B1 (enExample) |
| CN (1) | CN1201003C (enExample) |
| AT (1) | ATE327328T1 (enExample) |
| AU (1) | AU743745B2 (enExample) |
| BR (1) | BR9810917A (enExample) |
| CA (1) | CA2296530A1 (enExample) |
| DE (1) | DE69834643T2 (enExample) |
| DK (1) | DK1002075T3 (enExample) |
| ES (1) | ES2264207T3 (enExample) |
| HU (1) | HUP0003762A3 (enExample) |
| IL (1) | IL134011A0 (enExample) |
| NO (1) | NO20000215L (enExample) |
| PL (1) | PL338139A1 (enExample) |
| RU (1) | RU2218402C2 (enExample) |
| WO (1) | WO1999004000A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020137890A1 (en) * | 1997-03-31 | 2002-09-26 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US6566499B1 (en) * | 1997-07-18 | 2003-05-20 | Zymogenetics, Inc. | Adipocyte-specific protein homologs |
| US6265544B1 (en) * | 1997-07-18 | 2001-07-24 | Zymogenetics, Inc. | Adipocyte-specific protein homologs |
| FR2767135B1 (fr) | 1997-08-06 | 2002-07-12 | Genset Sa | Recepteur complexe lsr, activite, clonage, et application au diagnostic, a la prevention et/ou au traitement de d'obesite et des risques ou complications associes |
| US20030129691A1 (en) * | 1998-02-09 | 2003-07-10 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US7300774B1 (en) | 1999-12-09 | 2007-11-27 | The Regents Of The University Of California | Multimeric fusion proteins of the TNF superfamily ligands |
| US6544946B1 (en) * | 1999-02-19 | 2003-04-08 | Zymogenetics, Inc. | Inhibitors for use in hemostasis and immune function |
| AU772103B2 (en) | 1999-02-19 | 2004-04-08 | Zymogenetics Inc. | Inhibitors for use in hemostasis and immune function |
| US20040014650A1 (en) * | 2002-07-17 | 2004-01-22 | Sheppard Paul D | Methods for enhancing wound repair |
| AU5037100A (en) * | 1999-05-27 | 2000-12-18 | Zymogenetics Inc. | Adipocyte complement related protein homolog zacrp6 |
| JP2003501027A (ja) * | 1999-05-27 | 2003-01-14 | ザイモジェネティクス，インコーポレイティド | 脂肪細胞補体関連タンパク質同族体ｚａｃｒｐ５ |
| US20050042719A1 (en) * | 1999-05-27 | 2005-02-24 | Zymogenetics, Inc. | Adipocyte complement related protein homolog zacrp5 |
| DE60043367D1 (de) * | 1999-06-15 | 2009-12-31 | Genentech Inc | Sekretierte und Transmembran-Polypeptide sowie Nukleinsäuren zu deren Kodierung |
| JP2003504022A (ja) * | 1999-07-01 | 2003-02-04 | ザイモジェネティクス，インコーポレイティド | 分泌されるタンパク質ｚａｃｒｐ４ |
| DE19963859A1 (de) * | 1999-12-30 | 2001-07-12 | Apotech Res & Dev Ltd | Bi- oder Oligomer eines Di-, Tri-, Quattro- oder Pentamers von rekombinanten Fusionsproteinen |
| AU2001297656A1 (en) * | 2000-11-29 | 2002-09-19 | Zymogenetics, Inc. | Adipocyte complement related protein zacrp11 |
| IL156864A0 (en) | 2001-01-16 | 2004-02-08 | Genset Sa | Polynucleotides and polypeptides and their use in metabolic disorders |
| WO2002055694A2 (en) * | 2001-01-16 | 2002-07-18 | Genset Sa | Discriminative nucleic acid analysis using clone sequence signatures |
| US20030220253A1 (en) * | 2002-03-08 | 2003-11-27 | Lasser Gerald W. | Inhibitors for use in hemostasis |
| JP2008507591A (ja) * | 2004-05-21 | 2008-03-13 | ゼンコー・インコーポレイテッド | 免疫原性が改変されたＣ１ｑファミリーメンバータンパク質 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0679716A4 (en) * | 1993-11-12 | 1999-06-09 | Kenichi Matsubara | GENE SIGNATURE. |
| US5869330A (en) * | 1995-06-05 | 1999-02-09 | Whitehead Institute For Biomedical Research | DNA encoding a novel serum protein produced exclusively in adipocytes |
| US6265544B1 (en) * | 1997-07-18 | 2001-07-24 | Zymogenetics, Inc. | Adipocyte-specific protein homologs |
| NZ522634A (en) * | 1997-12-03 | 2004-02-27 | Genentech Inc | PRO243 encoding a polypeptide with homology to chordin and antibodies and vectors |
-
1998
- 1998-07-17 US US09/118,408 patent/US6265544B1/en not_active Expired - Lifetime
- 1998-07-17 IL IL13401198A patent/IL134011A0/xx unknown
- 1998-07-17 BR BR9810917-0A patent/BR9810917A/pt not_active Application Discontinuation
- 1998-07-17 JP JP2000503206A patent/JP3762220B2/ja not_active Expired - Fee Related
- 1998-07-17 CN CNB988089114A patent/CN1201003C/zh not_active Expired - Fee Related
- 1998-07-17 DK DK98934630T patent/DK1002075T3/da active
- 1998-07-17 PL PL98338139A patent/PL338139A1/xx not_active IP Right Cessation
- 1998-07-17 CA CA002296530A patent/CA2296530A1/en not_active Abandoned
- 1998-07-17 WO PCT/US1998/014864 patent/WO1999004000A1/en not_active Ceased
- 1998-07-17 ES ES98934630T patent/ES2264207T3/es not_active Expired - Lifetime
- 1998-07-17 KR KR10-2000-7000538A patent/KR100385868B1/ko not_active Expired - Fee Related
- 1998-07-17 AU AU84113/98A patent/AU743745B2/en not_active Ceased
- 1998-07-17 RU RU2000103824/13A patent/RU2218402C2/ru not_active IP Right Cessation
- 1998-07-17 EP EP98934630A patent/EP1002075B1/en not_active Expired - Lifetime
- 1998-07-17 AT AT98934630T patent/ATE327328T1/de not_active IP Right Cessation
- 1998-07-17 HU HU0003762A patent/HUP0003762A3/hu unknown
- 1998-07-17 DE DE69834643T patent/DE69834643T2/de not_active Expired - Fee Related
-
2000
- 2000-01-17 NO NO20000215A patent/NO20000215L/no not_active Application Discontinuation
-
2001
- 2001-07-23 US US09/911,176 patent/US6518403B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU743745B2 (en) | 2002-02-07 |
| HUP0003762A2 (hu) | 2001-08-28 |
| NO20000215L (no) | 2000-03-17 |
| KR100385868B1 (ko) | 2003-06-02 |
| DE69834643D1 (de) | 2006-06-29 |
| AU8411398A (en) | 1999-02-10 |
| CN1201003C (zh) | 2005-05-11 |
| CN1272883A (zh) | 2000-11-08 |
| RU2218402C2 (ru) | 2003-12-10 |
| ES2264207T3 (es) | 2006-12-16 |
| JP3762220B2 (ja) | 2006-04-05 |
| PL338139A1 (en) | 2000-09-25 |
| KR20010021973A (ko) | 2001-03-15 |
| BR9810917A (pt) | 2000-08-15 |
| US6518403B2 (en) | 2003-02-11 |
| DE69834643T2 (de) | 2007-05-10 |
| WO1999004000A1 (en) | 1999-01-28 |
| JP2001510045A (ja) | 2001-07-31 |
| DK1002075T3 (da) | 2006-09-18 |
| IL134011A0 (en) | 2001-04-30 |
| ATE327328T1 (de) | 2006-06-15 |
| US6265544B1 (en) | 2001-07-24 |
| US20020156243A1 (en) | 2002-10-24 |
| EP1002075B1 (en) | 2006-05-24 |
| EP1002075A1 (en) | 2000-05-24 |
| HUP0003762A3 (en) | 2005-11-28 |
| NO20000215D0 (no) | 2000-01-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |