BR9810917A - Polipeptìdeo isolado, proteìna de fusão, vetor de expressão, célula cultivada, processo para produzir um polipeptìdeo, composição farmacêutica, anticorpo, proteìna de ligação, polinucleotìdeo isolado, e, sonda de oligonucleotìdeo ou iniciador - Google Patents
Polipeptìdeo isolado, proteìna de fusão, vetor de expressão, célula cultivada, processo para produzir um polipeptìdeo, composição farmacêutica, anticorpo, proteìna de ligação, polinucleotìdeo isolado, e, sonda de oligonucleotìdeo ou iniciadorInfo
- Publication number
- BR9810917A BR9810917A BR9810917-0A BR9810917A BR9810917A BR 9810917 A BR9810917 A BR 9810917A BR 9810917 A BR9810917 A BR 9810917A BR 9810917 A BR9810917 A BR 9810917A
- Authority
- BR
- Brazil
- Prior art keywords
- polypeptide
- isolated
- antibody
- pharmaceutical composition
- produce
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 7
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 7
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
- 108091033319 polynucleotide Proteins 0.000 title abstract 4
- 102000040430 polynucleotide Human genes 0.000 title abstract 4
- 239000002157 polynucleotide Substances 0.000 title abstract 4
- 239000013604 expression vector Substances 0.000 title abstract 2
- 108020001507 fusion proteins Proteins 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 102000014914 Carrier Proteins Human genes 0.000 title 1
- 108020005187 Oligonucleotide Probes Proteins 0.000 title 1
- -1 antibody Proteins 0.000 title 1
- 108091008324 binding proteins Proteins 0.000 title 1
- 210000004748 cultured cell Anatomy 0.000 title 1
- 102000037865 fusion proteins Human genes 0.000 title 1
- 239000002751 oligonucleotide probe Substances 0.000 title 1
- 239000013615 primer Substances 0.000 title 1
- 239000002987 primer (paints) Substances 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 238000006471 dimerization reaction Methods 0.000 abstract 1
- 238000006384 oligomerization reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5315497P | 1997-07-18 | 1997-07-18 | |
| PCT/US1998/014864 WO1999004000A1 (en) | 1997-07-18 | 1998-07-17 | Adipocyte-specific protein homologs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9810917A true BR9810917A (pt) | 2000-08-15 |
Family
ID=21982287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9810917-0A BR9810917A (pt) | 1997-07-18 | 1998-07-17 | Polipeptìdeo isolado, proteìna de fusão, vetor de expressão, célula cultivada, processo para produzir um polipeptìdeo, composição farmacêutica, anticorpo, proteìna de ligação, polinucleotìdeo isolado, e, sonda de oligonucleotìdeo ou iniciador |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US6265544B1 (enExample) |
| EP (1) | EP1002075B1 (enExample) |
| JP (1) | JP3762220B2 (enExample) |
| KR (1) | KR100385868B1 (enExample) |
| CN (1) | CN1201003C (enExample) |
| AT (1) | ATE327328T1 (enExample) |
| AU (1) | AU743745B2 (enExample) |
| BR (1) | BR9810917A (enExample) |
| CA (1) | CA2296530A1 (enExample) |
| DE (1) | DE69834643T2 (enExample) |
| DK (1) | DK1002075T3 (enExample) |
| ES (1) | ES2264207T3 (enExample) |
| HU (1) | HUP0003762A3 (enExample) |
| IL (1) | IL134011A0 (enExample) |
| NO (1) | NO20000215L (enExample) |
| PL (1) | PL338139A1 (enExample) |
| RU (1) | RU2218402C2 (enExample) |
| WO (1) | WO1999004000A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020137890A1 (en) * | 1997-03-31 | 2002-09-26 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| EP1002075B1 (en) * | 1997-07-18 | 2006-05-24 | ZymoGenetics, Inc. | Adipocyte-specific protein homologs |
| US6566499B1 (en) * | 1997-07-18 | 2003-05-20 | Zymogenetics, Inc. | Adipocyte-specific protein homologs |
| FR2767135B1 (fr) * | 1997-08-06 | 2002-07-12 | Genset Sa | Recepteur complexe lsr, activite, clonage, et application au diagnostic, a la prevention et/ou au traitement de d'obesite et des risques ou complications associes |
| US20030129691A1 (en) * | 1998-02-09 | 2003-07-10 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US7300774B1 (en) * | 1999-12-09 | 2007-11-27 | The Regents Of The University Of California | Multimeric fusion proteins of the TNF superfamily ligands |
| US6544946B1 (en) * | 1999-02-19 | 2003-04-08 | Zymogenetics, Inc. | Inhibitors for use in hemostasis and immune function |
| US20040014650A1 (en) * | 2002-07-17 | 2004-01-22 | Sheppard Paul D | Methods for enhancing wound repair |
| HK1039892A1 (zh) * | 1999-02-19 | 2002-05-17 | Zymogenetics, Inc. | 止血和免疫功能的抑制剂 |
| US20050042719A1 (en) * | 1999-05-27 | 2005-02-24 | Zymogenetics, Inc. | Adipocyte complement related protein homolog zacrp5 |
| AU5037100A (en) * | 1999-05-27 | 2000-12-18 | Zymogenetics Inc. | Adipocyte complement related protein homolog zacrp6 |
| WO2000073444A1 (en) * | 1999-05-27 | 2000-12-07 | Zymogenetics, Inc. | Adipocyte complement related protein homolog zacrp5 |
| EP1953173B1 (en) * | 1999-06-15 | 2009-11-18 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids endoding the same |
| WO2001002565A2 (en) * | 1999-07-01 | 2001-01-11 | Zymogenetics, Inc. | Secreted protein zacrp4 |
| DE19963859A1 (de) * | 1999-12-30 | 2001-07-12 | Apotech Res & Dev Ltd | Bi- oder Oligomer eines Di-, Tri-, Quattro- oder Pentamers von rekombinanten Fusionsproteinen |
| AU2001297656A1 (en) * | 2000-11-29 | 2002-09-19 | Zymogenetics, Inc. | Adipocyte complement related protein zacrp11 |
| US7348406B2 (en) | 2001-01-16 | 2008-03-25 | Serono Genetics Institute S.A. | Metabolic gene polynucleotides and polypeptides and uses thereof |
| US7326678B2 (en) | 2001-01-16 | 2008-02-05 | Serono Genetics Institute S.A. | GMG-3 GMG-4 and GMG-6 polynucleotides and polypeptides and uses thereof |
| CA2478675A1 (en) * | 2002-03-08 | 2003-09-18 | Zymogenetics, Inc. | Inhibitors for use in hemostasis |
| EP1756159A1 (en) * | 2004-05-21 | 2007-02-28 | Xencor, Inc. | C1q family member proteins with altered immunogenicity |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2153480A1 (en) | 1993-11-12 | 1995-06-01 | Kenichi Matsubara | Gene signature |
| US5869330A (en) | 1995-06-05 | 1999-02-09 | Whitehead Institute For Biomedical Research | DNA encoding a novel serum protein produced exclusively in adipocytes |
| EP1002075B1 (en) * | 1997-07-18 | 2006-05-24 | ZymoGenetics, Inc. | Adipocyte-specific protein homologs |
| NZ522634A (en) * | 1997-12-03 | 2004-02-27 | Genentech Inc | PRO243 encoding a polypeptide with homology to chordin and antibodies and vectors |
-
1998
- 1998-07-17 EP EP98934630A patent/EP1002075B1/en not_active Expired - Lifetime
- 1998-07-17 KR KR10-2000-7000538A patent/KR100385868B1/ko not_active Expired - Fee Related
- 1998-07-17 AU AU84113/98A patent/AU743745B2/en not_active Ceased
- 1998-07-17 DE DE69834643T patent/DE69834643T2/de not_active Expired - Fee Related
- 1998-07-17 WO PCT/US1998/014864 patent/WO1999004000A1/en not_active Ceased
- 1998-07-17 PL PL98338139A patent/PL338139A1/xx not_active IP Right Cessation
- 1998-07-17 ES ES98934630T patent/ES2264207T3/es not_active Expired - Lifetime
- 1998-07-17 CN CNB988089114A patent/CN1201003C/zh not_active Expired - Fee Related
- 1998-07-17 BR BR9810917-0A patent/BR9810917A/pt not_active Application Discontinuation
- 1998-07-17 HU HU0003762A patent/HUP0003762A3/hu unknown
- 1998-07-17 CA CA002296530A patent/CA2296530A1/en not_active Abandoned
- 1998-07-17 IL IL13401198A patent/IL134011A0/xx unknown
- 1998-07-17 US US09/118,408 patent/US6265544B1/en not_active Expired - Lifetime
- 1998-07-17 JP JP2000503206A patent/JP3762220B2/ja not_active Expired - Fee Related
- 1998-07-17 RU RU2000103824/13A patent/RU2218402C2/ru not_active IP Right Cessation
- 1998-07-17 DK DK98934630T patent/DK1002075T3/da active
- 1998-07-17 AT AT98934630T patent/ATE327328T1/de not_active IP Right Cessation
-
2000
- 2000-01-17 NO NO20000215A patent/NO20000215L/no not_active Application Discontinuation
-
2001
- 2001-07-23 US US09/911,176 patent/US6518403B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1002075B1 (en) | 2006-05-24 |
| RU2218402C2 (ru) | 2003-12-10 |
| HUP0003762A3 (en) | 2005-11-28 |
| DE69834643T2 (de) | 2007-05-10 |
| HUP0003762A2 (hu) | 2001-08-28 |
| JP3762220B2 (ja) | 2006-04-05 |
| KR100385868B1 (ko) | 2003-06-02 |
| KR20010021973A (ko) | 2001-03-15 |
| NO20000215D0 (no) | 2000-01-17 |
| EP1002075A1 (en) | 2000-05-24 |
| IL134011A0 (en) | 2001-04-30 |
| WO1999004000A1 (en) | 1999-01-28 |
| JP2001510045A (ja) | 2001-07-31 |
| NO20000215L (no) | 2000-03-17 |
| US20020156243A1 (en) | 2002-10-24 |
| AU8411398A (en) | 1999-02-10 |
| AU743745B2 (en) | 2002-02-07 |
| ES2264207T3 (es) | 2006-12-16 |
| US6265544B1 (en) | 2001-07-24 |
| PL338139A1 (en) | 2000-09-25 |
| CN1201003C (zh) | 2005-05-11 |
| CA2296530A1 (en) | 1999-01-28 |
| ATE327328T1 (de) | 2006-06-15 |
| DE69834643D1 (de) | 2006-06-29 |
| CN1272883A (zh) | 2000-11-08 |
| DK1002075T3 (da) | 2006-09-18 |
| US6518403B2 (en) | 2003-02-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: DE ACORDO COM O ART 36 DA LPI (LEI 9.279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR. |