RU2218402C2 - Выделенный полипептид, имеющий гомологию относительно комплемент родственного белка адипоцитов (варианты), гибридный белок (варианты), экспрессирующий вектор, способ получения полипептида, поликлональное антитело, фрагмент выделенного полинуклеотида (варианты) - Google Patents

Выделенный полипептид, имеющий гомологию относительно комплемент родственного белка адипоцитов (варианты), гибридный белок (варианты), экспрессирующий вектор, способ получения полипептида, поликлональное антитело, фрагмент выделенного полинуклеотида (варианты) Download PDF

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RU2218402C2
RU2218402C2 RU2000103824/13A RU2000103824A RU2218402C2 RU 2218402 C2 RU2218402 C2 RU 2218402C2 RU 2000103824/13 A RU2000103824/13 A RU 2000103824/13A RU 2000103824 A RU2000103824 A RU 2000103824A RU 2218402 C2 RU2218402 C2 RU 2218402C2
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seq
amino acid
acid sequence
polypeptide
positions
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RU2000103824/13A
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Russian (ru)
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RU2000103824A (ru
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Пол О. ШЕППАРД
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Займодженетикс, Инк.
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
RU2000103824/13A 1997-07-18 1998-07-17 Выделенный полипептид, имеющий гомологию относительно комплемент родственного белка адипоцитов (варианты), гибридный белок (варианты), экспрессирующий вектор, способ получения полипептида, поликлональное антитело, фрагмент выделенного полинуклеотида (варианты) RU2218402C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5315497P 1997-07-18 1997-07-18
US60/053,154 1997-07-18

Publications (2)

Publication Number Publication Date
RU2000103824A RU2000103824A (ru) 2001-12-10
RU2218402C2 true RU2218402C2 (ru) 2003-12-10

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RU2000103824/13A RU2218402C2 (ru) 1997-07-18 1998-07-17 Выделенный полипептид, имеющий гомологию относительно комплемент родственного белка адипоцитов (варианты), гибридный белок (варианты), экспрессирующий вектор, способ получения полипептида, поликлональное антитело, фрагмент выделенного полинуклеотида (варианты)

Country Status (18)

Country Link
US (2) US6265544B1 (enExample)
EP (1) EP1002075B1 (enExample)
JP (1) JP3762220B2 (enExample)
KR (1) KR100385868B1 (enExample)
CN (1) CN1201003C (enExample)
AT (1) ATE327328T1 (enExample)
AU (1) AU743745B2 (enExample)
BR (1) BR9810917A (enExample)
CA (1) CA2296530A1 (enExample)
DE (1) DE69834643T2 (enExample)
DK (1) DK1002075T3 (enExample)
ES (1) ES2264207T3 (enExample)
HU (1) HUP0003762A3 (enExample)
IL (1) IL134011A0 (enExample)
NO (1) NO20000215L (enExample)
PL (1) PL338139A1 (enExample)
RU (1) RU2218402C2 (enExample)
WO (1) WO1999004000A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US6566499B1 (en) * 1997-07-18 2003-05-20 Zymogenetics, Inc. Adipocyte-specific protein homologs
HUP0003762A3 (en) * 1997-07-18 2005-11-28 Zymogenetics Inc Adipocyte-specific protein homologs
FR2767135B1 (fr) 1997-08-06 2002-07-12 Genset Sa Recepteur complexe lsr, activite, clonage, et application au diagnostic, a la prevention et/ou au traitement de d'obesite et des risques ou complications associes
US20030129691A1 (en) * 1998-02-09 2003-07-10 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7300774B1 (en) 1999-12-09 2007-11-27 The Regents Of The University Of California Multimeric fusion proteins of the TNF superfamily ligands
US20040014650A1 (en) * 2002-07-17 2004-01-22 Sheppard Paul D Methods for enhancing wound repair
US6544946B1 (en) 1999-02-19 2003-04-08 Zymogenetics, Inc. Inhibitors for use in hemostasis and immune function
AU772103B2 (en) 1999-02-19 2004-04-08 Zymogenetics Inc. Inhibitors for use in hemostasis and immune function
WO2000073444A1 (en) * 1999-05-27 2000-12-07 Zymogenetics, Inc. Adipocyte complement related protein homolog zacrp5
US20050042719A1 (en) * 1999-05-27 2005-02-24 Zymogenetics, Inc. Adipocyte complement related protein homolog zacrp5
WO2000073446A2 (en) * 1999-05-27 2000-12-07 Zymogenetics, Inc. Adipocyte complement related protein homolog zacrp6
EP1978029A3 (en) * 1999-06-15 2008-10-15 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids endoding the same
CA2378951A1 (en) * 1999-07-01 2001-01-11 Zymogenetics, Inc. Secreted protein zacrp4
DE19963859A1 (de) * 1999-12-30 2001-07-12 Apotech Res & Dev Ltd Bi- oder Oligomer eines Di-, Tri-, Quattro- oder Pentamers von rekombinanten Fusionsproteinen
US20020160474A1 (en) * 2000-11-29 2002-10-31 Fox Brian A. Adipocyte complement related protein zacrp11
JP2004531234A (ja) 2001-01-16 2004-10-14 ジェンセット Gmg−3、gmg−4、およびgmg−6ポリヌクレオチドおよびポリペプチド並びにそれらの使用
US7348406B2 (en) 2001-01-16 2008-03-25 Serono Genetics Institute S.A. Metabolic gene polynucleotides and polypeptides and uses thereof
WO2003075848A2 (en) * 2002-03-08 2003-09-18 Zymogenetics, Inc. Inhibitors for use in hemostasis
JP2008507591A (ja) * 2004-05-21 2008-03-13 ゼンコー・インコーポレイテッド 免疫原性が改変されたC1qファミリーメンバータンパク質

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0679716A4 (en) 1993-11-12 1999-06-09 Kenichi Matsubara GENE SIGNATURE.
US5869330A (en) * 1995-06-05 1999-02-09 Whitehead Institute For Biomedical Research DNA encoding a novel serum protein produced exclusively in adipocytes
HUP0003762A3 (en) * 1997-07-18 2005-11-28 Zymogenetics Inc Adipocyte-specific protein homologs
AU736506B2 (en) * 1997-12-03 2001-07-26 Genentech Inc. Polypeptides and nucleic acids encoding the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NAKANO Y. et al., Isolation and characterisation. of GBP28, a novel gelatin-binding protein purified from human plasma, Journal of Biochemistry, vol. 120, 1996, p. 803-812. *

Also Published As

Publication number Publication date
CA2296530A1 (en) 1999-01-28
JP3762220B2 (ja) 2006-04-05
DK1002075T3 (da) 2006-09-18
KR20010021973A (ko) 2001-03-15
CN1201003C (zh) 2005-05-11
JP2001510045A (ja) 2001-07-31
EP1002075B1 (en) 2006-05-24
DE69834643D1 (de) 2006-06-29
NO20000215L (no) 2000-03-17
WO1999004000A1 (en) 1999-01-28
EP1002075A1 (en) 2000-05-24
HUP0003762A2 (hu) 2001-08-28
AU8411398A (en) 1999-02-10
CN1272883A (zh) 2000-11-08
IL134011A0 (en) 2001-04-30
PL338139A1 (en) 2000-09-25
BR9810917A (pt) 2000-08-15
US20020156243A1 (en) 2002-10-24
ES2264207T3 (es) 2006-12-16
US6265544B1 (en) 2001-07-24
HUP0003762A3 (en) 2005-11-28
AU743745B2 (en) 2002-02-07
DE69834643T2 (de) 2007-05-10
NO20000215D0 (no) 2000-01-17
ATE327328T1 (de) 2006-06-15
US6518403B2 (en) 2003-02-11
KR100385868B1 (ko) 2003-06-02

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Effective date: 20070718