CN1186014C - 程序化和随时间释放的多颗粒药物剂型及其制备方法 - Google Patents

程序化和随时间释放的多颗粒药物剂型及其制备方法 Download PDF

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Publication number
CN1186014C
CN1186014C CNB998074322A CN99807432A CN1186014C CN 1186014 C CN1186014 C CN 1186014C CN B998074322 A CNB998074322 A CN B998074322A CN 99807432 A CN99807432 A CN 99807432A CN 1186014 C CN1186014 C CN 1186014C
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CN
China
Prior art keywords
pharmaceutical dosage
polymer
dosage form
water
described pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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CNB998074322A
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English (en)
Chinese (zh)
Other versions
CN1305371A (zh
Inventor
E·根德罗特
G·考森
F·拉格特
M－C·克里－博维特
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Laboratories Prographarm SA
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Laboratories Prographarm SA
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Publication of CN1305371A publication Critical patent/CN1305371A/zh
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Publication of CN1186014C publication Critical patent/CN1186014C/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNB998074322A 1998-05-20 1999-05-20 程序化和随时间释放的多颗粒药物剂型及其制备方法 Expired - Lifetime CN1186014C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR98/06384 1998-05-20
FR9806384A FR2778848B1 (fr) 1998-05-20 1998-05-20 Forme pharmaceutique multiparticulaire a liberation programmee et pulsee et son procede de preparation

Publications (2)

Publication Number Publication Date
CN1305371A CN1305371A (zh) 2001-07-25
CN1186014C true CN1186014C (zh) 2005-01-26

Family

ID=9526556

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998074322A Expired - Lifetime CN1186014C (zh) 1998-05-20 1999-05-20 程序化和随时间释放的多颗粒药物剂型及其制备方法

Country Status (24)

Country Link
EP (1) EP1077687B1 (enExample)
JP (1) JP2002515423A (enExample)
KR (1) KR100583065B1 (enExample)
CN (1) CN1186014C (enExample)
AT (1) ATE214598T1 (enExample)
AU (1) AU758299B2 (enExample)
BG (1) BG64764B1 (enExample)
BR (1) BR9910606A (enExample)
CA (1) CA2333188C (enExample)
DE (1) DE69901062T2 (enExample)
DK (1) DK1077687T3 (enExample)
ES (1) ES2173739T3 (enExample)
FR (1) FR2778848B1 (enExample)
GE (1) GEP20022750B (enExample)
HU (1) HU224193B1 (enExample)
IL (1) IL139774A (enExample)
MX (1) MXPA00011364A (enExample)
NO (1) NO330501B1 (enExample)
NZ (1) NZ508392A (enExample)
PL (1) PL192950B1 (enExample)
PT (1) PT1077687E (enExample)
TR (1) TR200100107T2 (enExample)
WO (1) WO1999059557A1 (enExample)
ZA (1) ZA200006768B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US8802139B2 (en) 2003-06-26 2014-08-12 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
US20060105039A1 (en) 2004-10-21 2006-05-18 Jin-Wang Lai Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
AU2013273835B2 (en) * 2005-05-02 2016-07-07 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
US9161918B2 (en) * 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
WO2008136016A1 (en) * 2007-05-08 2008-11-13 Medreich Limited A stable controlled release oral solid dosage form composition and a process thereof
NZ600256A (en) 2009-12-02 2014-05-30 Aptalis Pharma Ltd Fexofenadine microcapsules and compositions containing them
FR2999432B1 (fr) 2012-12-17 2014-12-12 Ethypharm Sa Comprimes orodispersibles obtenus par compression moulage

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2558396B2 (ja) * 1990-06-28 1996-11-27 田辺製薬株式会社 放出制御型製剤
US5567441A (en) * 1995-03-24 1996-10-22 Andrx Pharmaceuticals Inc. Diltiazem controlled release formulation
FR2754710B1 (fr) * 1996-10-22 1998-12-31 Prographarm Lab Procede de preparation d'une forme pharmaceutique multiparticulaire a liberation controlee plurisequentielle

Also Published As

Publication number Publication date
BG64764B1 (bg) 2006-03-31
DE69901062T2 (de) 2002-10-31
HUP0102027A3 (en) 2002-12-28
KR100583065B1 (ko) 2006-06-08
BR9910606A (pt) 2001-10-02
AU3830299A (en) 1999-12-06
EP1077687A1 (fr) 2001-02-28
BG104963A (en) 2001-07-31
ATE214598T1 (de) 2002-04-15
CN1305371A (zh) 2001-07-25
CA2333188C (fr) 2010-07-06
ES2173739T3 (es) 2002-10-16
HU224193B1 (hu) 2005-06-28
NO330501B1 (no) 2011-05-02
DE69901062D1 (de) 2002-04-25
NO20005838D0 (no) 2000-11-17
NO20005838L (no) 2001-01-10
PT1077687E (pt) 2002-09-30
TR200100107T2 (tr) 2001-06-21
NZ508392A (en) 2002-09-27
EP1077687B1 (fr) 2002-03-20
HK1033271A1 (en) 2001-08-24
AU758299B2 (en) 2003-03-20
IL139774A0 (en) 2002-02-10
FR2778848A1 (fr) 1999-11-26
DK1077687T3 (da) 2002-06-17
KR20010052370A (ko) 2001-06-25
CA2333188A1 (fr) 1999-11-25
FR2778848B1 (fr) 2001-11-23
PL344314A1 (en) 2001-10-22
HUP0102027A2 (hu) 2002-03-28
WO1999059557A1 (fr) 1999-11-25
GEP20022750B (en) 2002-08-26
MXPA00011364A (es) 2008-09-09
JP2002515423A (ja) 2002-05-28
ZA200006768B (en) 2001-11-20
IL139774A (en) 2005-09-25
PL192950B1 (pl) 2006-12-29

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Granted publication date: 20050126