FR2778848B1 - Forme pharmaceutique multiparticulaire a liberation programmee et pulsee et son procede de preparation - Google Patents

Forme pharmaceutique multiparticulaire a liberation programmee et pulsee et son procede de preparation

Info

Publication number
FR2778848B1
FR2778848B1 FR9806384A FR9806384A FR2778848B1 FR 2778848 B1 FR2778848 B1 FR 2778848B1 FR 9806384 A FR9806384 A FR 9806384A FR 9806384 A FR9806384 A FR 9806384A FR 2778848 B1 FR2778848 B1 FR 2778848B1
Authority
FR
France
Prior art keywords
active principle
polymer
hours
preparation
coating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9806384A
Other languages
English (en)
French (fr)
Other versions
FR2778848A1 (fr
Inventor
Edouard Gendrot
Francoise Di Costanzo Ragot
Gerard Cousin
Bouvet Marie Christine Clee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratories Prographarm SA
Original Assignee
Laboratories Prographarm SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9806384A priority Critical patent/FR2778848B1/fr
Application filed by Laboratories Prographarm SA filed Critical Laboratories Prographarm SA
Priority to MXPA00011364A priority patent/MXPA00011364A/es
Priority to AU38302/99A priority patent/AU758299B2/en
Priority to NZ508392A priority patent/NZ508392A/xx
Priority to GEAP19995632A priority patent/GEP20022750B/en
Priority to ES99920897T priority patent/ES2173739T3/es
Priority to JP2000549222A priority patent/JP2002515423A/ja
Priority to PCT/FR1999/001201 priority patent/WO1999059557A1/fr
Priority to DE69901062T priority patent/DE69901062T2/de
Priority to IL13977499A priority patent/IL139774A/xx
Priority to HU0102027A priority patent/HU224193B1/hu
Priority to CNB998074322A priority patent/CN1186014C/zh
Priority to AT99920897T priority patent/ATE214598T1/de
Priority to PL344314A priority patent/PL192950B1/pl
Priority to CA2333188A priority patent/CA2333188C/fr
Priority to DK99920897T priority patent/DK1077687T3/da
Priority to BR9910606-0A priority patent/BR9910606A/pt
Priority to TR2001/00107T priority patent/TR200100107T2/xx
Priority to KR1020007013020A priority patent/KR100583065B1/ko
Priority to EP99920897A priority patent/EP1077687B1/fr
Priority to PT99920897T priority patent/PT1077687E/pt
Priority to HK01103971.6A priority patent/HK1033271B/xx
Publication of FR2778848A1 publication Critical patent/FR2778848A1/fr
Priority to BG104963A priority patent/BG64764B1/bg
Priority to NO20005838A priority patent/NO330501B1/no
Priority to ZA200006768A priority patent/ZA200006768B/en
Application granted granted Critical
Publication of FR2778848B1 publication Critical patent/FR2778848B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR9806384A 1998-05-20 1998-05-20 Forme pharmaceutique multiparticulaire a liberation programmee et pulsee et son procede de preparation Expired - Lifetime FR2778848B1 (fr)

Priority Applications (25)

Application Number Priority Date Filing Date Title
FR9806384A FR2778848B1 (fr) 1998-05-20 1998-05-20 Forme pharmaceutique multiparticulaire a liberation programmee et pulsee et son procede de preparation
DK99920897T DK1077687T3 (da) 1998-05-20 1999-05-20 Multipartikulær farmaceutisk form med programmeret og pulserende frigørelse og fremstillingsmetode deraf
NZ508392A NZ508392A (en) 1998-05-20 1999-05-20 Multiparticulate delayed release pharmaceutical form comprising at least two independent polymers with different permeability rates
GEAP19995632A GEP20022750B (en) 1998-05-20 1999-05-20 Multiparticulate Pharmaceutical Composition in the Form of Spheroids and Method for its Production
ES99920897T ES2173739T3 (es) 1998-05-20 1999-05-20 Forma farmaceutica multiparticular con liberacion programada y pulsada y su procedimiento de preparacion.
JP2000549222A JP2002515423A (ja) 1998-05-20 1999-05-20 プログラム放出性及びパルス放出性の多微粒子薬剤形態、及びその調製方法
PCT/FR1999/001201 WO1999059557A1 (fr) 1998-05-20 1999-05-20 Forme pharmaceutique multiparticulaire a liberation programmee et pulsee et son procede de preparation
DE69901062T DE69901062T2 (de) 1998-05-20 1999-05-20 Multipartikuläre pharmazeutische form mit gesteuerter und gepulster wirkstoffabgabe und verfahren zu deren herstellung
IL13977499A IL139774A (en) 1998-05-20 1999-05-20 Multiparticular pharmaceutical form with programmed and timed release and preparation method
HU0102027A HU224193B1 (hu) 1998-05-20 1999-05-20 Késleltetett és időzített hatóanyag-felszabadulást biztosító multipartikuláris gyógyszerforma
CNB998074322A CN1186014C (zh) 1998-05-20 1999-05-20 程序化和随时间释放的多颗粒药物剂型及其制备方法
AT99920897T ATE214598T1 (de) 1998-05-20 1999-05-20 Multipartikuläre pharmazeutische form mit gesteuerter und gepulster wirkstoffabgabe und verfahren zu deren herstellung
MXPA00011364A MXPA00011364A (es) 1998-05-20 1999-05-20 Forma farmaceutica de multiparticulas de liberacion programada y de tiempo y su procedimiento de preparacion.
CA2333188A CA2333188C (fr) 1998-05-20 1999-05-20 Forme pharmaceutique multiparticulaire a liberation programmee et pulsee et son procede de preparation
TR2001/00107T TR200100107T2 (tr) 1998-05-20 1999-05-20 Programlı ve fasılalı salınımlı çok parçacıklı farmasötik form ve hazırlanması için işlem.
PT99920897T PT1077687E (pt) 1998-05-20 1999-05-20 Forma farmaceutica em particulas multiplas com libertacao programada e pulsada e processo para a sua preparacao
BR9910606-0A BR9910606A (pt) 1998-05-20 1999-05-20 Forma farmacêutica multiparticular com liberação programada e pulsada e seu processo de preparo
KR1020007013020A KR100583065B1 (ko) 1998-05-20 1999-05-20 프로그램화 및 펄스화 방출식 다립형 의약 제형 및 그의 제조 방법
EP99920897A EP1077687B1 (fr) 1998-05-20 1999-05-20 Forme pharmaceutique multiparticulaire a liberation programmee et pulsee et son procede de preparation
AU38302/99A AU758299B2 (en) 1998-05-20 1999-05-20 Multiparticulate pharmaceutical form with programmed and timed release and preparation method
HK01103971.6A HK1033271B (en) 1998-05-20 1999-05-20 Multiparticulate pharmaceutical form with programmed and timed release and preparation method
PL344314A PL192950B1 (pl) 1998-05-20 1999-05-20 Wielocząstkowa postać farmaceutyczna o opóźnionym i stopniowym uwalnianiu, oraz sposób jej wytwarzania
BG104963A BG64764B1 (bg) 1998-05-20 2000-11-17 Многочастична фармацевтична форма със забавено и пулсационно освобождаване и метод за получаването й
NO20005838A NO330501B1 (no) 1998-05-20 2000-11-17 Farmasoytisk multipartikkelform med forsinket og pulset frigivning, samt fremstilling derav
ZA200006768A ZA200006768B (en) 1998-05-20 2000-11-20 Multiparticulate pharmaceutical form with programmed and timed release and preparation method.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9806384A FR2778848B1 (fr) 1998-05-20 1998-05-20 Forme pharmaceutique multiparticulaire a liberation programmee et pulsee et son procede de preparation

Publications (2)

Publication Number Publication Date
FR2778848A1 FR2778848A1 (fr) 1999-11-26
FR2778848B1 true FR2778848B1 (fr) 2001-11-23

Family

ID=9526556

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9806384A Expired - Lifetime FR2778848B1 (fr) 1998-05-20 1998-05-20 Forme pharmaceutique multiparticulaire a liberation programmee et pulsee et son procede de preparation

Country Status (24)

Country Link
EP (1) EP1077687B1 (enExample)
JP (1) JP2002515423A (enExample)
KR (1) KR100583065B1 (enExample)
CN (1) CN1186014C (enExample)
AT (1) ATE214598T1 (enExample)
AU (1) AU758299B2 (enExample)
BG (1) BG64764B1 (enExample)
BR (1) BR9910606A (enExample)
CA (1) CA2333188C (enExample)
DE (1) DE69901062T2 (enExample)
DK (1) DK1077687T3 (enExample)
ES (1) ES2173739T3 (enExample)
FR (1) FR2778848B1 (enExample)
GE (1) GEP20022750B (enExample)
HU (1) HU224193B1 (enExample)
IL (1) IL139774A (enExample)
MX (1) MXPA00011364A (enExample)
NO (1) NO330501B1 (enExample)
NZ (1) NZ508392A (enExample)
PL (1) PL192950B1 (enExample)
PT (1) PT1077687E (enExample)
TR (1) TR200100107T2 (enExample)
WO (1) WO1999059557A1 (enExample)
ZA (1) ZA200006768B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8802139B2 (en) 2003-06-26 2014-08-12 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
EP2417969A1 (en) 2004-10-21 2012-02-15 Aptalis Pharmatech, Inc. Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
AU2013273835B2 (en) * 2005-05-02 2016-07-07 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
WO2008136016A1 (en) * 2007-05-08 2008-11-13 Medreich Limited A stable controlled release oral solid dosage form composition and a process thereof
WO2011067667A2 (en) 2009-12-02 2011-06-09 Eurand Pharmaceuticals Limited Fexofenadine microcapsules and compositions containing them
FR2999432B1 (fr) 2012-12-17 2014-12-12 Ethypharm Sa Comprimes orodispersibles obtenus par compression moulage

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2558396B2 (ja) * 1990-06-28 1996-11-27 田辺製薬株式会社 放出制御型製剤
US5567441A (en) * 1995-03-24 1996-10-22 Andrx Pharmaceuticals Inc. Diltiazem controlled release formulation
FR2754710B1 (fr) * 1996-10-22 1998-12-31 Prographarm Lab Procede de preparation d'une forme pharmaceutique multiparticulaire a liberation controlee plurisequentielle

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8802139B2 (en) 2003-06-26 2014-08-12 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient

Also Published As

Publication number Publication date
ATE214598T1 (de) 2002-04-15
BG104963A (en) 2001-07-31
DK1077687T3 (da) 2002-06-17
FR2778848A1 (fr) 1999-11-26
MXPA00011364A (es) 2008-09-09
NO330501B1 (no) 2011-05-02
HUP0102027A2 (hu) 2002-03-28
AU3830299A (en) 1999-12-06
JP2002515423A (ja) 2002-05-28
DE69901062T2 (de) 2002-10-31
GEP20022750B (en) 2002-08-26
TR200100107T2 (tr) 2001-06-21
KR20010052370A (ko) 2001-06-25
HU224193B1 (hu) 2005-06-28
IL139774A0 (en) 2002-02-10
BG64764B1 (bg) 2006-03-31
AU758299B2 (en) 2003-03-20
CN1186014C (zh) 2005-01-26
HUP0102027A3 (en) 2002-12-28
NZ508392A (en) 2002-09-27
PL192950B1 (pl) 2006-12-29
PL344314A1 (en) 2001-10-22
IL139774A (en) 2005-09-25
KR100583065B1 (ko) 2006-06-08
BR9910606A (pt) 2001-10-02
EP1077687B1 (fr) 2002-03-20
DE69901062D1 (de) 2002-04-25
ZA200006768B (en) 2001-11-20
ES2173739T3 (es) 2002-10-16
CA2333188C (fr) 2010-07-06
NO20005838D0 (no) 2000-11-17
NO20005838L (no) 2001-01-10
CA2333188A1 (fr) 1999-11-25
HK1033271A1 (en) 2001-08-24
WO1999059557A1 (fr) 1999-11-25
CN1305371A (zh) 2001-07-25
PT1077687E (pt) 2002-09-30
EP1077687A1 (fr) 2001-02-28

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GC Lien (pledge) constituted

Effective date: 20160120

RG Lien (pledge) cancelled

Effective date: 20160226

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