ES2004693A6 - Un procedimiento para la preparacion de una composicion farmaceutica solida administrable por via oral, que contiene vinburnina como principio activo. - Google Patents

Un procedimiento para la preparacion de una composicion farmaceutica solida administrable por via oral, que contiene vinburnina como principio activo.

Info

Publication number
ES2004693A6
ES2004693A6 ES8700706A ES8700706A ES2004693A6 ES 2004693 A6 ES2004693 A6 ES 2004693A6 ES 8700706 A ES8700706 A ES 8700706A ES 8700706 A ES8700706 A ES 8700706A ES 2004693 A6 ES2004693 A6 ES 2004693A6
Authority
ES
Spain
Prior art keywords
vinburnine
preparing
pharmaceutical compositions
compositions containing
active principle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8700706A
Other languages
English (en)
Inventor
Paolo Chiesi
Luciana Pavesi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chiesi Farmaceutici SpA
Original Assignee
Chiesi Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farmaceutici SpA filed Critical Chiesi Farmaceutici SpA
Publication of ES2004693A6 publication Critical patent/ES2004693A6/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE UNA COMPOSICION FARMACEUTICA SOLIDA ADMINISTRABLE POR VIA ORAL, QUE CONTIENE VINBURNINA COMO PRINCIPIO ACTIVO. EL PROCEDIMIENTO CONSISTE EN APLICAR EL PRINCIPIO ACTIVO MEZCLADO CON EXCIPIENTE IDONEOS SOBRE GRANULOS INERTES (CONSTITUIDOS POR GRANULOS DE SACAROSA Y DE ALMIDON DE MAIZ) OBTENIENDOSE UNOS GRANULOS QUE SEREVISTEN CON UNA MEMBRANA RETARDANTE CONSTITUIDA POR UN POLIMERO ANIONICO DE ACIDO METACRILICO PARCIALMENTE ESTERIFICADO CON METILO. LAS COMPOSICIONES FARMACEUTICAS ASI OBTENIDAS, EN FORMA DE CAPSULAS O COMPRIMIDOS, ESTAN CONSTITUIDAS POR MICROGRANULOS QUE CONTIENEN EL PRINCIPIO ACTIVO, EXCIPIENTES DE GRANULACION Y UN ACIDO ORGANICO PARA REGULAR EL PH, REVESTIDOS POR UN POLIMERO ANIONICO; TIENEN MEJORADAS FAVORABLEMENTE LA FARMACOCINETICA Y BIO DISPONIBILIDAD DEL PRINCIPIO ACTIVO Y SON UTILES PARA EL TRATAMIENTO DE TRASTORNOS CEREBROVASCULARES.
ES8700706A 1986-03-14 1987-03-13 Un procedimiento para la preparacion de una composicion farmaceutica solida administrable por via oral, que contiene vinburnina como principio activo. Expired ES2004693A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19751/86A IT1204839B (it) 1986-03-14 1986-03-14 Composizioni farmaceutiche contenenti vinburnina e loro procedimento di preparazione

Publications (1)

Publication Number Publication Date
ES2004693A6 true ES2004693A6 (es) 1989-02-01

Family

ID=11160928

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8700706A Expired ES2004693A6 (es) 1986-03-14 1987-03-13 Un procedimiento para la preparacion de una composicion farmaceutica solida administrable por via oral, que contiene vinburnina como principio activo.

Country Status (8)

Country Link
BE (1) BE1000087A3 (es)
DE (1) DE3708068A1 (es)
ES (1) ES2004693A6 (es)
FR (1) FR2597340B1 (es)
GR (1) GR870422B (es)
IT (1) IT1204839B (es)
MY (1) MY102368A (es)
PT (1) PT84465B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113402506B (zh) * 2021-06-17 2023-06-16 四川大学 中间体和制备方法及其在合成长春布宁上的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2313915A1 (fr) * 1976-01-26 1977-01-07 Corneille Gilbert Nouvelle forme galenique d'administration de la vincamine et de ses derives, son procede de preparation et medicaments comprenant cette nouvelle forme
CH647676A5 (fr) * 1978-12-22 1985-02-15 Donald E Panoz Formes galeniques a usage oral, a liberation programmee et leurs procedes de preparation.

Also Published As

Publication number Publication date
DE3708068A1 (de) 1987-09-17
PT84465B (pt) 1989-10-04
FR2597340A1 (fr) 1987-10-23
IT8619751A0 (it) 1986-03-14
MY102368A (en) 1992-06-17
PT84465A (en) 1987-04-01
BE1000087A3 (fr) 1988-02-02
GR870422B (en) 1987-07-10
FR2597340B1 (fr) 1990-04-13
IT1204839B (it) 1989-03-10

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20020401