ES8702138A1 - Metodo de preparar composiciones farmaceuticas con perfil de desprendimiento controlado bifasico de sustancia activa desde un nucleo de farmaco y desde los poros de un revestimiento de membrana circundante del nucleo. - Google Patents

Metodo de preparar composiciones farmaceuticas con perfil de desprendimiento controlado bifasico de sustancia activa desde un nucleo de farmaco y desde los poros de un revestimiento de membrana circundante del nucleo.

Info

Publication number
ES8702138A1
ES8702138A1 ES546728A ES546728A ES8702138A1 ES 8702138 A1 ES8702138 A1 ES 8702138A1 ES 546728 A ES546728 A ES 546728A ES 546728 A ES546728 A ES 546728A ES 8702138 A1 ES8702138 A1 ES 8702138A1
Authority
ES
Spain
Prior art keywords
drug
controlled
tablet
active substance
medical preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES546728A
Other languages
English (en)
Other versions
ES546728A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leo AB
Original Assignee
Leo AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo AB filed Critical Leo AB
Publication of ES546728A0 publication Critical patent/ES546728A0/es
Publication of ES8702138A1 publication Critical patent/ES8702138A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Slot Machines And Peripheral Devices (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Control Of Temperature (AREA)

Abstract

METODO PARA PREPARAR COMPOSICIONES FARMACEUTICAS CON PERFIL DE DESPRENDIMIENTO BIFASICO. COMPRENDE: A) DISOLVER UN POLIMERO FORMADOR DE PELICULA SELECCIONADO DEL GUPO COMPUESTO POR DERIVADOS DE CELULOSA, POLIMEROS ACRILICOS Y POLIMEROS VINILICOS, QUE ES INSOLUBLE EN AGUA Y FLUIDOS GASTROINTESTINALES, EN UN DISOLVENTE ORGANICO COMO LAS CETONAS; B) DISOLVER PARTICULAS DE 0,5 A 100 MM DE UN MATERIAL CREADOR DE POROS QUE INCLUYE UNA SUSTANCIA ACTIVA COMO FARMACO EN CANTIDAD TERAPEUTICAMENTE EFICAZ, QUE PUEDE SER IGUAL O DISTINTA A LA DE LA TABLETA; C) PREPARAR UNA SUSPENSION CON A) Y B) PARA FORMAR UN FLUIDO DE REVESTIMIENTO; Y D) APLICAR EL FLUIDO DE REVESTIMIENTO A UNA TABLETA DE FARMACO DURANTE DE 10 MINUTOS A 10 HORAS, A UNA TEMPERATURA DE 5 A 80JC, Y DEJARLO SECAR PARA OBTENER UNA TABLETA REVESTIDA. UTILIZABLE PARA FABRICACION DE MEDICAMENTOS QUE PROPORCIONAN DOS SUSTANCIAS ACTIVAS EN COMBINACION.
ES546728A 1984-09-06 1985-09-05 Metodo de preparar composiciones farmaceuticas con perfil de desprendimiento controlado bifasico de sustancia activa desde un nucleo de farmaco y desde los poros de un revestimiento de membrana circundante del nucleo. Expired ES8702138A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8404467A SE8404467D0 (sv) 1984-09-06 1984-09-06 Controlled-release medical preparations

Publications (2)

Publication Number Publication Date
ES546728A0 ES546728A0 (es) 1986-12-16
ES8702138A1 true ES8702138A1 (es) 1986-12-16

Family

ID=20356934

Family Applications (1)

Application Number Title Priority Date Filing Date
ES546728A Expired ES8702138A1 (es) 1984-09-06 1985-09-05 Metodo de preparar composiciones farmaceuticas con perfil de desprendimiento controlado bifasico de sustancia activa desde un nucleo de farmaco y desde los poros de un revestimiento de membrana circundante del nucleo.

Country Status (21)

Country Link
US (1) US4824678A (es)
EP (1) EP0173928B1 (es)
JP (1) JP2527713B2 (es)
KR (1) KR930003114B1 (es)
AT (1) ATE53490T1 (es)
AU (1) AU576891B2 (es)
CA (1) CA1252723A (es)
DE (1) DE3578123D1 (es)
DK (1) DK164256C (es)
ES (1) ES8702138A1 (es)
FI (1) FI87042C (es)
GR (1) GR852158B (es)
HU (1) HU194495B (es)
IE (1) IE58263B1 (es)
IL (2) IL76257A (es)
NO (1) NO169996C (es)
NZ (1) NZ213245A (es)
PH (1) PH22119A (es)
PT (1) PT81092B (es)
SE (1) SE8404467D0 (es)
ZA (1) ZA856547B (es)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE56999B1 (en) * 1983-12-22 1992-03-11 Elan Corp Plc Pharmaceutical formulation
US4917899A (en) * 1983-12-22 1990-04-17 Elan Corporation Plc Controlled absorption diltiazem formulation
DK62184D0 (da) * 1984-02-10 1984-02-10 Benzon As Alfred Diffusionsovertrukket polydepotpraeparat
IE59287B1 (en) * 1984-02-10 1994-02-09 Benzon Pharma As Diffusion coated multiple-units dosage form
US5624683A (en) * 1986-08-06 1997-04-29 Eisai Co., Ltd. Sustained-release multi-granule tablet
DE3720757A1 (de) * 1987-06-24 1989-01-05 Bayer Ag Dhp-manteltablette
US5073381A (en) * 1988-08-15 1991-12-17 University Of Akron Amphiphilic networks
US5612059A (en) * 1988-08-30 1997-03-18 Pfizer Inc. Use of asymmetric membranes in delivery devices
SE8803822D0 (sv) * 1988-10-26 1988-10-26 Novel dosage form
US5178868A (en) * 1988-10-26 1993-01-12 Kabi Pharmacia Aktiebolaq Dosage form
US5240601A (en) * 1988-11-09 1993-08-31 Chembiomed, Ltd. Affinity supports for hemoperfusion
US5149425A (en) * 1988-11-09 1992-09-22 Chembiomed, Ltd. Affinity supports for hemoperfusion
ES2067957T3 (es) * 1990-08-07 1995-04-01 Pfizer Uso de membranas polimerizadas interfacialmente en dispositivos de liberacion.
US5288505A (en) * 1991-06-26 1994-02-22 Galephar P.R., Inc., Ltd. Extended release form of diltiazem
US5407686A (en) * 1991-11-27 1995-04-18 Sidmak Laboratories, Inc. Sustained release composition for oral administration of active ingredient
JPH0733645A (ja) * 1992-05-28 1995-02-03 Elan Corp Plc 錠剤製剤
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
ATE258685T1 (de) * 1993-03-09 2004-02-15 Baxter Int Makromolekulare mikropartikel und verfahren zur ihrer herstellung
US5547948A (en) * 1995-01-17 1996-08-20 American Home Products Corporation Controlled release of steroids from sugar coatings
EP1005863A1 (en) * 1998-12-04 2000-06-07 Synthelabo Controlled-release dosage forms comprising a short acting hypnotic or a salt thereof
EP1064937A1 (en) * 1999-06-28 2001-01-03 Sanofi-Synthelabo Timed dual release dosage forms comprising a short acting hypnotic or a salt thereof
GB9923045D0 (en) * 1999-09-29 1999-12-01 Novartis Ag New oral formulations
US7108866B1 (en) 1999-12-10 2006-09-19 Biovall Laboratories International Srl Chronotherapeutic diltiazem formulations and the administration thereof
US20060153914A1 (en) * 1999-12-10 2006-07-13 Biovail Laboratories International S.R.L. Chronotherapeutic diltiazem formulations and the administration thereof
WO2001045668A2 (en) 1999-12-20 2001-06-28 Schering Corporation Stable extended release oral dosage composition comprising pseudoephedrine and desloratadine
AU2276801A (en) 1999-12-20 2001-07-03 Schering Corporation Extended release oral dosage composition
SE0100200D0 (sv) 2001-01-24 2001-01-24 Astrazeneca Ab New film coating
US6960357B2 (en) 2001-05-25 2005-11-01 Mistral Pharma Inc. Chemical delivery device
ATE477795T1 (de) * 2001-07-04 2010-09-15 Sun Pharma Advanced Res Co Ltd Magenretentionssystem mit kontrollierter arzneimittelfreisetzung
US6602911B2 (en) * 2001-11-05 2003-08-05 Cypress Bioscience, Inc. Methods of treating fibromyalgia
WO2003051340A1 (en) 2001-12-19 2003-06-26 Astrazeneca Ab New film coating
PL223471B1 (pl) * 2002-03-15 2016-10-31 Cypress Bioscience Inc Kompozycja farmaceutyczna zawierająca milnacypran do stosowania w leczeniu zespołu nadwrażliwości jelita grubego
US20060003004A1 (en) * 2002-10-25 2006-01-05 Collegium Pharmaceutical, Inc. Pulsatile release compositions of milnacipran
US20040121010A1 (en) * 2002-10-25 2004-06-24 Collegium Pharmaceutical, Inc. Pulsatile release compositions of milnacipran
GB0227948D0 (en) * 2002-11-29 2003-01-08 Cipla Ltd Pharmaceutical combinations comprising b-2 adrenoreceptor agonists and xanthines
US20040228830A1 (en) * 2003-01-28 2004-11-18 Collegium Pharmaceutical, Inc. Multiparticulate compositions of milnacipran for oral administration
US7862835B2 (en) * 2004-10-27 2011-01-04 Boston Scientific Scimed, Inc. Method of manufacturing a medical device having a porous coating thereon
US7994220B2 (en) * 2005-09-28 2011-08-09 Cypress Bioscience, Inc. Milnacipran for the long-term treatment of fibromyalgia syndrome
US8148393B2 (en) * 2005-11-18 2012-04-03 Synthon Bv Zolpidem tablets
US7427414B2 (en) * 2006-01-18 2008-09-23 Astron Research Limited Modified release oral dosage form using co-polymer of polyvinyl acetate
CN102440992A (zh) * 2011-12-19 2012-05-09 岳阳新华达制药有限公司 含有盐酸班布特罗和多索茶碱复方制剂及其制备方法
WO2017026950A1 (en) 2015-08-07 2017-02-16 Santa Farma Ilac San. A. S. Controlled release propiverine formulations
EP3796908B1 (en) 2018-11-16 2023-05-10 Santa Farma Ilaç Sanayi A.S. Controlled release propiverine formulations
WO2022115056A1 (en) 2020-11-27 2022-06-02 Santa Farma Ilac Sanayii A.S. Sustained release formulation compositions comprising propiverine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL108838C (es) * 1956-03-27
US3538214A (en) * 1969-04-22 1970-11-03 Merck & Co Inc Controlled release medicinal tablets
EP0013131A3 (en) * 1978-12-27 1981-01-07 Mundipharma A.G. Pharmaceutical composition in solid dosage form, and process for its production
US4557925A (en) * 1982-07-08 1985-12-10 Ab Ferrosan Membrane-coated sustained-release tablets and method
JPH075457B2 (ja) * 1983-08-16 1995-01-25 ザ ウエルカム フアウンデ−シヨン リミテツド 調節された方法による有効成分の放出を可能にする医薬組成物
US4769027A (en) * 1984-08-15 1988-09-06 Burroughs Wellcome Co. Delivery system

Also Published As

Publication number Publication date
AU576891B2 (en) 1988-09-08
HUT40333A (en) 1986-12-28
US4824678A (en) 1989-04-25
AU4693585A (en) 1986-03-13
JPS61112013A (ja) 1986-05-30
NO853407L (no) 1986-03-07
CA1252723A (en) 1989-04-18
DK164256C (da) 1992-10-19
GR852158B (es) 1986-01-08
IL76256A0 (en) 1986-01-31
HU194495B (en) 1988-02-29
KR930003114B1 (ko) 1993-04-19
SE8404467D0 (sv) 1984-09-06
FI853406L (fi) 1986-03-07
FI853406A0 (fi) 1985-09-05
PT81092B (pt) 1988-01-22
IE58263B1 (en) 1993-08-25
ES546728A0 (es) 1986-12-16
ZA856547B (en) 1986-04-30
EP0173928B1 (en) 1990-06-13
NO169996C (no) 1992-09-02
IL76256A (en) 1990-06-10
DK164256B (da) 1992-06-01
DK400685A (da) 1986-03-07
ATE53490T1 (de) 1990-06-15
KR860002271A (ko) 1986-04-24
IL76257A (en) 1989-05-15
PT81092A (en) 1985-10-01
NO169996B (no) 1992-05-25
DK400685D0 (da) 1985-09-02
DE3578123D1 (de) 1990-07-19
PH22119A (en) 1988-06-01
NZ213245A (en) 1988-06-30
EP0173928A1 (en) 1986-03-12
FI87042C (fi) 1992-11-25
IE852070L (en) 1986-03-06
JP2527713B2 (ja) 1996-08-28
FI87042B (fi) 1992-08-14

Similar Documents

Publication Publication Date Title
ES8702138A1 (es) Metodo de preparar composiciones farmaceuticas con perfil de desprendimiento controlado bifasico de sustancia activa desde un nucleo de farmaco y desde los poros de un revestimiento de membrana circundante del nucleo.
IE883810L (en) Sustained release pharmaceutical compositions
HUT59321A (en) Process for producing pharmaceutical compositions having controlled release of active ingredient
NO175186C (no) Fremgangsmåte for fremstilling av et osmotisk avgivende, oralt avleveringssystem inneholdende et moderat vannopplöselig, farmasöytisk akseptabelt salt av metoprolol
EP0171528A3 (en) Controlled release pharmaceutical preparations
CA2000932A1 (en) Oral pharmaceutical controlled release multiple unit dosage form
DE69508580D1 (en) Pellets
AU574220B2 (en) Sustained release drug in ter polymer coat (pvc and pvacand pvom)
AUPM814994A0 (en) Codeine-containing formulations
ES2004693A6 (es) Un procedimiento para la preparacion de una composicion farmaceutica solida administrable por via oral, que contiene vinburnina como principio activo.
ATE104847T1 (de) Feste und poroese einzeldosisform, enthaltend perlpartikel und verfahren zu ihrer herstellung.
ES8704080A1 (es) Metodo para producir una tableta farmaceutica revestida esencialmente con un terpolimero de poli (cloruro de vinilo) poli (acetato de vinilo) y poli (alcohol vinilico)
MY103627A (en) A controlled release pharmaceutical dosage form and a process for preparing same.
TH4686EX (th) การเตรียมยาชนิดใหม่สำหรับการใช้ทางปาก