CN1170933C - 促胃动素同系物 - Google Patents

促胃动素同系物 Download PDF

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Publication number
CN1170933C
CN1170933C CNB988046822A CN98804682A CN1170933C CN 1170933 C CN1170933 C CN 1170933C CN B988046822 A CNB988046822 A CN B988046822A CN 98804682 A CN98804682 A CN 98804682A CN 1170933 C CN1170933 C CN 1170933C
Authority
CN
China
Prior art keywords
polypeptide
seq
residue
amino acid
forming
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB988046822A
Other languages
English (en)
Chinese (zh)
Other versions
CN1254375A (zh
Inventor
P・O・舍帕德
P·O·舍帕德
戴舍尔
T·A·戴舍尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/822,897 external-priority patent/US6380158B1/en
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of CN1254375A publication Critical patent/CN1254375A/zh
Application granted granted Critical
Publication of CN1170933C publication Critical patent/CN1170933C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CNB988046822A 1997-03-24 1998-03-23 促胃动素同系物 Expired - Fee Related CN1170933C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US4110297P 1997-03-24 1997-03-24
US08/822,897 US6380158B1 (en) 1997-03-24 1997-03-24 Motilin homologs
US60/041,102 1997-03-24
US08/822,897 1997-03-24

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNB2004100567973A Division CN100410375C (zh) 1997-03-24 1998-03-23 促胃动素同系物抗体

Publications (2)

Publication Number Publication Date
CN1254375A CN1254375A (zh) 2000-05-24
CN1170933C true CN1170933C (zh) 2004-10-13

Family

ID=26717805

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB988046822A Expired - Fee Related CN1170933C (zh) 1997-03-24 1998-03-23 促胃动素同系物

Country Status (9)

Country Link
JP (1) JP4335318B2 (fr)
KR (1) KR20010005701A (fr)
CN (1) CN1170933C (fr)
AU (1) AU726423B2 (fr)
BR (1) BR9808059A (fr)
CA (1) CA2284733C (fr)
NO (1) NO994614L (fr)
NZ (1) NZ337958A (fr)
WO (1) WO1998042840A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627729B1 (en) 1997-03-24 2003-09-30 Zymogenetics, Inc. TML peptides
AU5911000A (en) * 1999-06-30 2001-01-31 Zymogenetics Inc. Sgip peptides
US6420521B1 (en) 1999-06-30 2002-07-16 Zymogenetics, Inc. Short gastrointestinal peptides
DK1197496T3 (da) * 1999-07-23 2007-10-22 Kenji Kangawa Hidtil ukendte peptider
CA2392019A1 (fr) 1999-11-22 2001-05-31 Zymogenetics, Inc. Methode permettant de produire un complexe forme d'un recepteur peptidique et de zsig33
US6897286B2 (en) 2000-05-11 2005-05-24 Zymogenetics, Inc. Zsig33-like peptides
WO2001087933A2 (fr) * 2000-05-11 2001-11-22 Zymogenetics, Inc. Peptides de type zsig33
US6967237B2 (en) 2000-05-30 2005-11-22 Merck & Co., Inc. Ghrelin analogs
US7521420B2 (en) 2003-06-18 2009-04-21 Tranzyme Pharma, Inc. Macrocyclic antagonists of the motilin receptor
JP5684474B2 (ja) 2006-09-11 2015-03-11 オセラ セラピューティクス， インコーポレイテッド 胃腸の運動障害疾患の治療のためのモチリン受容体の大環状アンタゴニスト
AU2010279076B2 (en) * 2009-07-29 2014-09-25 Daiichi Sankyo Company,Limited Motilin-like peptide compound having transmucosal absorbability imparted thereto
JP7049775B2 (ja) 2017-04-03 2022-04-07 リンナイ株式会社 表示装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8611832D0 (en) 1986-05-15 1986-06-25 Holland I B Polypeptide
US5006469A (en) * 1988-02-09 1991-04-09 Oregon Health Sciences University Vectors and host cells expressing prepromotilin and motilin-associated peptide (MAP)
US5037743A (en) 1988-08-05 1991-08-06 Zymogenetics, Inc. BAR1 secretion signal
JPH04299990A (ja) * 1991-03-27 1992-10-23 Sanwa Kagaku Kenkyusho Co Ltd モチリンアナログの精製方法

Also Published As

Publication number Publication date
CA2284733A1 (fr) 1998-10-01
NO994614D0 (no) 1999-09-23
NZ337958A (en) 2001-03-30
AU726423B2 (en) 2000-11-09
JP2001513651A (ja) 2001-09-04
AU6576998A (en) 1998-10-20
BR9808059A (pt) 2000-03-08
NO994614L (no) 1999-11-23
KR20010005701A (ko) 2001-01-15
CA2284733C (fr) 2010-10-26
JP4335318B2 (ja) 2009-09-30
CN1254375A (zh) 2000-05-24
WO1998042840A1 (fr) 1998-10-01

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