BR9808059A - Molécula de plinucleotìdeo isolada codificando um polipeptìdeo, polinucleotìdeo, vetor de expressão, célula cultivada, polipeptìdeo isolado, composição farmacêutica, anticorpo, processos para produzir polipeptìdeo zsig33, e, para estimular a motilidde gástrica - Google Patents

Molécula de plinucleotìdeo isolada codificando um polipeptìdeo, polinucleotìdeo, vetor de expressão, célula cultivada, polipeptìdeo isolado, composição farmacêutica, anticorpo, processos para produzir polipeptìdeo zsig33, e, para estimular a motilidde gástrica

Info

Publication number
BR9808059A
BR9808059A BR9808059-8A BR9808059A BR9808059A BR 9808059 A BR9808059 A BR 9808059A BR 9808059 A BR9808059 A BR 9808059A BR 9808059 A BR9808059 A BR 9808059A
Authority
BR
Brazil
Prior art keywords
polypeptide
isolated
processes
antibody
pharmaceutical composition
Prior art date
Application number
BR9808059-8A
Other languages
English (en)
Inventor
Paul O Sheppard
Theresa A Deisher
Original Assignee
Zimogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/822,897 external-priority patent/US6380158B1/en
Application filed by Zimogenetics Inc filed Critical Zimogenetics Inc
Publication of BR9808059A publication Critical patent/BR9808059A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

"MOLéCULAS DE POLINUCLEOTìDEO ISOLADA CODIFICANDO UM POLIPEPTìDEO, POLINUCLEOTìDEO, VETOR DE EXPRESSãO, CéLULA CULTIVADA, POLIPEPTìDEO ISOLADO, COMPOSIçãO FARMACêUTICA, ANTICORPO, PROCESSOS PARA PRODUZIR POLIPEPTìDEO ZSIG33, E, PARA ESTIMULAR A MOTILIDADE GáSTRICA". A presente invenção é dirigida a polinucleotídeos, polipeptídeos e fragmentos de peptídeos dos mesmos, e usos dos mesmos para uma nova sequência de cDNA que tem homologia para motilina. A distribuição de tecido de mRNA para o novo polipeptídeo é específica para o estómago, intestino delgado e pâncreas. A presente invenção ainda inclui agonistas, antagonistas, anticorpos, células hospedeitas, expressando o cDNA codificando os novos homólogos de motilina e processos para aumentar a motilidade gástrica usando as novas moléculas.
BR9808059-8A 1997-03-24 1998-03-23 Molécula de plinucleotìdeo isolada codificando um polipeptìdeo, polinucleotìdeo, vetor de expressão, célula cultivada, polipeptìdeo isolado, composição farmacêutica, anticorpo, processos para produzir polipeptìdeo zsig33, e, para estimular a motilidde gástrica BR9808059A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4110297P 1997-03-24 1997-03-24
US08/822,897 US6380158B1 (en) 1997-03-24 1997-03-24 Motilin homologs
PCT/US1998/005620 WO1998042840A1 (en) 1997-03-24 1998-03-23 Motilin homologs

Publications (1)

Publication Number Publication Date
BR9808059A true BR9808059A (pt) 2000-03-08

Family

ID=26717805

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9808059-8A BR9808059A (pt) 1997-03-24 1998-03-23 Molécula de plinucleotìdeo isolada codificando um polipeptìdeo, polinucleotìdeo, vetor de expressão, célula cultivada, polipeptìdeo isolado, composição farmacêutica, anticorpo, processos para produzir polipeptìdeo zsig33, e, para estimular a motilidde gástrica

Country Status (9)

Country Link
JP (1) JP4335318B2 (pt)
KR (1) KR20010005701A (pt)
CN (1) CN1170933C (pt)
AU (1) AU726423B2 (pt)
BR (1) BR9808059A (pt)
CA (1) CA2284733C (pt)
NO (1) NO994614L (pt)
NZ (1) NZ337958A (pt)
WO (1) WO1998042840A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627729B1 (en) 1997-03-24 2003-09-30 Zymogenetics, Inc. TML peptides
AU5911000A (en) * 1999-06-30 2001-01-31 Zymogenetics Inc. Sgip peptides
US6420521B1 (en) 1999-06-30 2002-07-16 Zymogenetics, Inc. Short gastrointestinal peptides
DK1197496T3 (da) * 1999-07-23 2007-10-22 Kenji Kangawa Hidtil ukendte peptider
CA2392019A1 (en) 1999-11-22 2001-05-31 Zymogenetics, Inc. Method of forming a peptide-receptor complex with zsig33
US6897286B2 (en) 2000-05-11 2005-05-24 Zymogenetics, Inc. Zsig33-like peptides
WO2001087933A2 (en) * 2000-05-11 2001-11-22 Zymogenetics, Inc. Zsig33-like peptides
US6967237B2 (en) 2000-05-30 2005-11-22 Merck & Co., Inc. Ghrelin analogs
US7521420B2 (en) 2003-06-18 2009-04-21 Tranzyme Pharma, Inc. Macrocyclic antagonists of the motilin receptor
JP5684474B2 (ja) 2006-09-11 2015-03-11 オセラ セラピューティクス， インコーポレイテッド 胃腸の運動障害疾患の治療のためのモチリン受容体の大環状アンタゴニスト
AU2010279076B2 (en) * 2009-07-29 2014-09-25 Daiichi Sankyo Company,Limited Motilin-like peptide compound having transmucosal absorbability imparted thereto
JP7049775B2 (ja) 2017-04-03 2022-04-07 リンナイ株式会社 表示装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8611832D0 (en) 1986-05-15 1986-06-25 Holland I B Polypeptide
US5006469A (en) * 1988-02-09 1991-04-09 Oregon Health Sciences University Vectors and host cells expressing prepromotilin and motilin-associated peptide (MAP)
US5037743A (en) 1988-08-05 1991-08-06 Zymogenetics, Inc. BAR1 secretion signal
JPH04299990A (ja) * 1991-03-27 1992-10-23 Sanwa Kagaku Kenkyusho Co Ltd モチリンアナログの精製方法

Also Published As

Publication number Publication date
CA2284733A1 (en) 1998-10-01
CN1170933C (zh) 2004-10-13
NO994614D0 (no) 1999-09-23
NZ337958A (en) 2001-03-30
AU726423B2 (en) 2000-11-09
JP2001513651A (ja) 2001-09-04
AU6576998A (en) 1998-10-20
NO994614L (no) 1999-11-23
KR20010005701A (ko) 2001-01-15
CA2284733C (en) 2010-10-26
JP4335318B2 (ja) 2009-09-30
CN1254375A (zh) 2000-05-24
WO1998042840A1 (en) 1998-10-01

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Legal Events

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B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: DE ACORDO COM O ART. 37, INDEFIRO O PRESENTE PEDIDO, UMA VEZ QUE NAO PREENCHE O DISPOSTO NO ART. 8O COMBINADO COM O ART. 13 DA LPI, ALEM DE REIVINDICAR MATERIA QUE NAO E PASSIVEL DE PRIVILEGIO DE ACORDO COM O DISPOSTO NO ARTIGO 10 (IX) DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

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