NZ337958A - Motilin homolog designated zsig33 for treating gastrointestinal cell contractility, secretion of digestive enzymes, gastrointestinal motility, recruitment of digestive enzymes, reflux disease and regulation of nutrient absorption - Google Patents

Motilin homolog designated zsig33 for treating gastrointestinal cell contractility, secretion of digestive enzymes, gastrointestinal motility, recruitment of digestive enzymes, reflux disease and regulation of nutrient absorption

Info

Publication number
NZ337958A
NZ337958A NZ337958A NZ33795898A NZ337958A NZ 337958 A NZ337958 A NZ 337958A NZ 337958 A NZ337958 A NZ 337958A NZ 33795898 A NZ33795898 A NZ 33795898A NZ 337958 A NZ337958 A NZ 337958A
Authority
NZ
New Zealand
Prior art keywords
digestive enzymes
motilin
zsig33
recruitment
secretion
Prior art date
Application number
NZ337958A
Other languages
English (en)
Inventor
Paul O Sheppard
Theresa A Deisher
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/822,897 external-priority patent/US6380158B1/en
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of NZ337958A publication Critical patent/NZ337958A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NZ337958A 1997-03-24 1998-03-23 Motilin homolog designated zsig33 for treating gastrointestinal cell contractility, secretion of digestive enzymes, gastrointestinal motility, recruitment of digestive enzymes, reflux disease and regulation of nutrient absorption NZ337958A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4110297P 1997-03-24 1997-03-24
US08/822,897 US6380158B1 (en) 1997-03-24 1997-03-24 Motilin homologs
PCT/US1998/005620 WO1998042840A1 (en) 1997-03-24 1998-03-23 Motilin homologs

Publications (1)

Publication Number Publication Date
NZ337958A true NZ337958A (en) 2001-03-30

Family

ID=26717805

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ337958A NZ337958A (en) 1997-03-24 1998-03-23 Motilin homolog designated zsig33 for treating gastrointestinal cell contractility, secretion of digestive enzymes, gastrointestinal motility, recruitment of digestive enzymes, reflux disease and regulation of nutrient absorption

Country Status (9)

Country Link
JP (1) JP4335318B2 (xx)
KR (1) KR20010005701A (xx)
CN (1) CN1170933C (xx)
AU (1) AU726423B2 (xx)
BR (1) BR9808059A (xx)
CA (1) CA2284733C (xx)
NO (1) NO994614L (xx)
NZ (1) NZ337958A (xx)
WO (1) WO1998042840A1 (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627729B1 (en) 1997-03-24 2003-09-30 Zymogenetics, Inc. TML peptides
US6420521B1 (en) 1999-06-30 2002-07-16 Zymogenetics, Inc. Short gastrointestinal peptides
CA2377721A1 (en) * 1999-06-30 2001-01-04 Zymogenetics, Inc. Sgip peptides
PT1197496E (pt) * 1999-07-23 2007-08-29 Kenji Kangawa Novos péptidos
ATE435871T1 (de) 1999-11-22 2009-07-15 Zymogenetics Inc Methode zur bildung einen peptid-rezeptor komplex mit zsig33 polypeptiden.
WO2001087933A2 (en) * 2000-05-11 2001-11-22 Zymogenetics, Inc. Zsig33-like peptides
US6897286B2 (en) 2000-05-11 2005-05-24 Zymogenetics, Inc. Zsig33-like peptides
US6967237B2 (en) 2000-05-30 2005-11-22 Merck & Co., Inc. Ghrelin analogs
EP1633774B1 (en) 2003-06-18 2010-02-17 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor
CN101528765B (zh) 2006-09-11 2015-04-22 欧塞拉治疗有限公司 用于治疗胃肠动力障碍病症的促胃动素受体的大环拮抗剂
CN102574904B (zh) * 2009-07-29 2014-11-26 第一三共株式会社 赋予了经粘膜吸收性的胃动素样肽化合物
JP7049775B2 (ja) 2017-04-03 2022-04-07 リンナイ株式会社 表示装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8611832D0 (en) 1986-05-15 1986-06-25 Holland I B Polypeptide
US5006469A (en) * 1988-02-09 1991-04-09 Oregon Health Sciences University Vectors and host cells expressing prepromotilin and motilin-associated peptide (MAP)
US5037743A (en) 1988-08-05 1991-08-06 Zymogenetics, Inc. BAR1 secretion signal
JPH04299990A (ja) * 1991-03-27 1992-10-23 Sanwa Kagaku Kenkyusho Co Ltd モチリンアナログの精製方法

Also Published As

Publication number Publication date
WO1998042840A1 (en) 1998-10-01
JP4335318B2 (ja) 2009-09-30
NO994614D0 (no) 1999-09-23
AU6576998A (en) 1998-10-20
CN1170933C (zh) 2004-10-13
KR20010005701A (ko) 2001-01-15
CA2284733C (en) 2010-10-26
AU726423B2 (en) 2000-11-09
NO994614L (no) 1999-11-23
CN1254375A (zh) 2000-05-24
JP2001513651A (ja) 2001-09-04
CA2284733A1 (en) 1998-10-01
BR9808059A (pt) 2000-03-08

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