NZ337958A - Motilin homolog designated zsig33 for treating gastrointestinal cell contractility, secretion of digestive enzymes, gastrointestinal motility, recruitment of digestive enzymes, reflux disease and regulation of nutrient absorption - Google Patents

Motilin homolog designated zsig33 for treating gastrointestinal cell contractility, secretion of digestive enzymes, gastrointestinal motility, recruitment of digestive enzymes, reflux disease and regulation of nutrient absorption

Info

Publication number
NZ337958A
NZ337958A NZ337958A NZ33795898A NZ337958A NZ 337958 A NZ337958 A NZ 337958A NZ 337958 A NZ337958 A NZ 337958A NZ 33795898 A NZ33795898 A NZ 33795898A NZ 337958 A NZ337958 A NZ 337958A
Authority
NZ
New Zealand
Prior art keywords
digestive enzymes
motilin
zsig33
recruitment
secretion
Prior art date
Application number
NZ337958A
Other languages
English (en)
Inventor
Paul O Sheppard
Theresa A Deisher
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/822,897 external-priority patent/US6380158B1/en
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of NZ337958A publication Critical patent/NZ337958A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NZ337958A 1997-03-24 1998-03-23 Motilin homolog designated zsig33 for treating gastrointestinal cell contractility, secretion of digestive enzymes, gastrointestinal motility, recruitment of digestive enzymes, reflux disease and regulation of nutrient absorption NZ337958A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4110297P 1997-03-24 1997-03-24
US08/822,897 US6380158B1 (en) 1997-03-24 1997-03-24 Motilin homologs
PCT/US1998/005620 WO1998042840A1 (fr) 1997-03-24 1998-03-23 Homologues de la motiline

Publications (1)

Publication Number Publication Date
NZ337958A true NZ337958A (en) 2001-03-30

Family

ID=26717805

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ337958A NZ337958A (en) 1997-03-24 1998-03-23 Motilin homolog designated zsig33 for treating gastrointestinal cell contractility, secretion of digestive enzymes, gastrointestinal motility, recruitment of digestive enzymes, reflux disease and regulation of nutrient absorption

Country Status (9)

Country Link
JP (1) JP4335318B2 (fr)
KR (1) KR20010005701A (fr)
CN (1) CN1170933C (fr)
AU (1) AU726423B2 (fr)
BR (1) BR9808059A (fr)
CA (1) CA2284733C (fr)
NO (1) NO994614L (fr)
NZ (1) NZ337958A (fr)
WO (1) WO1998042840A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627729B1 (en) 1997-03-24 2003-09-30 Zymogenetics, Inc. TML peptides
JP2003503055A (ja) * 1999-06-30 2003-01-28 ザイモジェネティクス，インコーポレイティド Ｓｇｉｐペプチド
US6420521B1 (en) 1999-06-30 2002-07-16 Zymogenetics, Inc. Short gastrointestinal peptides
US7385026B1 (en) * 1999-07-23 2008-06-10 Kenji Kangawa Modified ghrelin polypeptides
JP4800537B2 (ja) * 1999-11-22 2011-10-26 ザイモジェネティクス， インコーポレイテッド Ｚｓｉｇ３３によるペプチド−受容体複合体の形成方法
DE60142511D1 (de) * 2000-05-11 2010-08-19 Zymogenetics Inc Zsig33-ähnliche peptide
US6897286B2 (en) 2000-05-11 2005-05-24 Zymogenetics, Inc. Zsig33-like peptides
US6967237B2 (en) 2000-05-30 2005-11-22 Merck & Co., Inc. Ghrelin analogs
EP1633774B1 (fr) 2003-06-18 2010-02-17 Tranzyme Pharma Inc. Antagonistes macrocycliques du recepteur de motiline
CA2662897C (fr) 2006-09-11 2017-11-07 Tranzyme Pharma, Inc. Antagonistes macrocycliques du recepteur de la motiline pour le traitement de troubles de dysmotilite gastro-intestinale
AU2010279076B2 (en) * 2009-07-29 2014-09-25 Daiichi Sankyo Company,Limited Motilin-like peptide compound having transmucosal absorbability imparted thereto
JP7049775B2 (ja) 2017-04-03 2022-04-07 リンナイ株式会社 表示装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8611832D0 (en) 1986-05-15 1986-06-25 Holland I B Polypeptide
US5006469A (en) * 1988-02-09 1991-04-09 Oregon Health Sciences University Vectors and host cells expressing prepromotilin and motilin-associated peptide (MAP)
US5037743A (en) 1988-08-05 1991-08-06 Zymogenetics, Inc. BAR1 secretion signal
JPH04299990A (ja) * 1991-03-27 1992-10-23 Sanwa Kagaku Kenkyusho Co Ltd モチリンアナログの精製方法

Also Published As

Publication number Publication date
JP2001513651A (ja) 2001-09-04
BR9808059A (pt) 2000-03-08
CN1254375A (zh) 2000-05-24
CA2284733A1 (fr) 1998-10-01
NO994614L (no) 1999-11-23
JP4335318B2 (ja) 2009-09-30
AU726423B2 (en) 2000-11-09
CA2284733C (fr) 2010-10-26
NO994614D0 (no) 1999-09-23
KR20010005701A (ko) 2001-01-15
CN1170933C (zh) 2004-10-13
WO1998042840A1 (fr) 1998-10-01
AU6576998A (en) 1998-10-20

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