CN1168715C - 新的苯磺胺化合物、其制备方法以及含有它们的药物组合物 - Google Patents
新的苯磺胺化合物、其制备方法以及含有它们的药物组合物 Download PDFInfo
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- CN1168715C CN1168715C CNB021241619A CN02124161A CN1168715C CN 1168715 C CN1168715 C CN 1168715C CN B021241619 A CNB021241619 A CN B021241619A CN 02124161 A CN02124161 A CN 02124161A CN 1168715 C CN1168715 C CN 1168715C
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0109338A FR2827287B1 (fr) | 2001-07-13 | 2001-07-13 | Nouveaux derives de benzene sulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR0109338 | 2001-07-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1397550A CN1397550A (zh) | 2003-02-19 |
| CN1168715C true CN1168715C (zh) | 2004-09-29 |
Family
ID=8865461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB021241619A Expired - Fee Related CN1168715C (zh) | 2001-07-13 | 2002-07-15 | 新的苯磺胺化合物、其制备方法以及含有它们的药物组合物 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6589956B2 (enExample) |
| EP (1) | EP1275644A1 (enExample) |
| JP (1) | JP4138382B2 (enExample) |
| KR (1) | KR100498864B1 (enExample) |
| CN (1) | CN1168715C (enExample) |
| AR (1) | AR036340A1 (enExample) |
| AU (1) | AU2002300093B2 (enExample) |
| BR (1) | BR0202674A (enExample) |
| CA (1) | CA2394037C (enExample) |
| EA (1) | EA005403B1 (enExample) |
| FR (1) | FR2827287B1 (enExample) |
| HU (1) | HUP0202286A2 (enExample) |
| MX (1) | MXPA02006852A (enExample) |
| NO (1) | NO323868B1 (enExample) |
| NZ (1) | NZ520140A (enExample) |
| PL (1) | PL354948A1 (enExample) |
| ZA (1) | ZA200205598B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101296914B (zh) * | 2005-08-26 | 2012-07-18 | 盐野义制药株式会社 | 具有ppar激动活性的衍生物 |
| WO2014047427A2 (en) | 2012-09-21 | 2014-03-27 | Vanderbilt University | Substituted benzofuran, benzothiophene and indole mcl-1 inhibitors |
| US10005728B2 (en) | 2013-08-28 | 2018-06-26 | Vanderbilt University | Substituted indole Mcl-1 inhibitors |
| CA2943815C (en) | 2014-03-27 | 2023-04-04 | Vanderbilt University | Substituted indole mcl-1 inhibitors |
| US9949965B2 (en) | 2014-10-17 | 2018-04-24 | Vanderbilt University | Tricyclic indole Mcl-1 inhibitors and uses thereof |
| EP4292662A3 (en) | 2016-03-04 | 2024-02-21 | Vanderbilt University | Substituted indole mcl-1 inhibitors |
| MX2022007947A (es) * | 2019-12-24 | 2022-07-27 | Sumitomo Pharma Co Ltd | Derivado de amida de acido alifatico. |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3468882A (en) * | 1966-10-07 | 1969-09-23 | Sterling Drug Inc | Phenylhydrazone derivatives as intermediates for preparing indoles |
| GB8419575D0 (en) * | 1984-08-01 | 1984-09-05 | Glaxo Group Ltd | Chemical compounds |
| KR940007458B1 (ko) * | 1991-11-21 | 1994-08-18 | 주식회사 금성사 | 박막 트랜지스터 제조 방법 |
| TW219358B (enExample) * | 1991-12-20 | 1994-01-21 | Hokuriku Pharmaceutical | |
| KR950704252A (ko) * | 1992-12-21 | 1995-11-17 | 우에하라 아키라 | N-치환 이미다졸 유도체 |
| GB9317764D0 (en) * | 1993-08-26 | 1993-10-13 | Pfizer Ltd | Therapeutic compound |
| FR2712591B1 (fr) * | 1993-11-19 | 1996-02-09 | Pf Medicament | Nouvelles arylpipérazines dérivées d'indole, leur préparation et leur utilisation thérapeutique. |
| KR100436812B1 (ko) * | 1995-01-06 | 2004-08-31 | 도레이 가부시끼가이샤 | 벤젠축합헤테로환유도체및그유도체를유효성분으로함유하는의약조성물 |
| WO1997016446A1 (en) * | 1995-11-02 | 1997-05-09 | Merck Sharp & Dohme Limited | Bicyclic heteroaryl-alkylene-(homo)piperazinones and thione analogues thereof, their preparation and their use as selective agonists of 5-ht1-like receptors |
| GB9523243D0 (en) * | 1995-11-14 | 1996-01-17 | Merck Sharp & Dohme | Therapeutic agents |
| GB9523250D0 (en) * | 1995-11-14 | 1996-01-17 | Merck Sharp & Dohme | Therapeutic agents |
-
2001
- 2001-07-13 FR FR0109338A patent/FR2827287B1/fr not_active Expired - Fee Related
-
2002
- 2002-07-08 PL PL02354948A patent/PL354948A1/xx not_active Application Discontinuation
- 2002-07-10 BR BR0202674-0A patent/BR0202674A/pt not_active IP Right Cessation
- 2002-07-10 JP JP2002200910A patent/JP4138382B2/ja not_active Expired - Fee Related
- 2002-07-11 MX MXPA02006852A patent/MXPA02006852A/es active IP Right Grant
- 2002-07-11 EP EP02291746A patent/EP1275644A1/fr not_active Withdrawn
- 2002-07-12 NZ NZ520140A patent/NZ520140A/en unknown
- 2002-07-12 US US10/195,031 patent/US6589956B2/en not_active Expired - Fee Related
- 2002-07-12 AR ARP020102608A patent/AR036340A1/es not_active Application Discontinuation
- 2002-07-12 AU AU2002300093A patent/AU2002300093B2/en not_active Ceased
- 2002-07-12 EA EA200200665A patent/EA005403B1/ru not_active IP Right Cessation
- 2002-07-12 NO NO20023389A patent/NO323868B1/no not_active IP Right Cessation
- 2002-07-12 ZA ZA200205598A patent/ZA200205598B/xx unknown
- 2002-07-12 HU HU0202286A patent/HUP0202286A2/hu unknown
- 2002-07-13 KR KR10-2002-0040945A patent/KR100498864B1/ko not_active Expired - Fee Related
- 2002-07-15 CA CA002394037A patent/CA2394037C/fr not_active Expired - Fee Related
- 2002-07-15 CN CNB021241619A patent/CN1168715C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR100498864B1 (ko) | 2005-07-04 |
| AR036340A1 (es) | 2004-09-01 |
| NO323868B1 (no) | 2007-07-16 |
| ZA200205598B (en) | 2003-03-27 |
| BR0202674A (pt) | 2003-05-06 |
| US20030109533A1 (en) | 2003-06-12 |
| EA200200665A1 (ru) | 2003-02-27 |
| US6589956B2 (en) | 2003-07-08 |
| NO20023389L (no) | 2003-01-14 |
| AU2002300093B2 (en) | 2007-07-12 |
| FR2827287A1 (fr) | 2003-01-17 |
| JP4138382B2 (ja) | 2008-08-27 |
| HU0202286D0 (enExample) | 2002-09-28 |
| EP1275644A1 (fr) | 2003-01-15 |
| FR2827287B1 (fr) | 2003-10-31 |
| KR20030007173A (ko) | 2003-01-23 |
| NO20023389D0 (no) | 2002-07-12 |
| CA2394037A1 (fr) | 2003-01-13 |
| CA2394037C (fr) | 2008-04-29 |
| CN1397550A (zh) | 2003-02-19 |
| HK1050681A1 (en) | 2003-07-04 |
| NZ520140A (en) | 2003-09-26 |
| MXPA02006852A (es) | 2005-07-25 |
| EA005403B1 (ru) | 2005-02-24 |
| HUP0202286A2 (hu) | 2003-08-28 |
| PL354948A1 (en) | 2003-01-27 |
| JP2003064055A (ja) | 2003-03-05 |
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