BR0202674A - Compostos de benzenossulfonamida, processo para a sua preparação e composições farmacêuticas contendo os mesmos - Google Patents

Compostos de benzenossulfonamida, processo para a sua preparação e composições farmacêuticas contendo os mesmos

Info

Publication number
BR0202674A
BR0202674A BR0202674-0A BR0202674A BR0202674A BR 0202674 A BR0202674 A BR 0202674A BR 0202674 A BR0202674 A BR 0202674A BR 0202674 A BR0202674 A BR 0202674A
Authority
BR
Brazil
Prior art keywords
group
preparation
pharmaceutical compositions
compositions containing
processes
Prior art date
Application number
BR0202674-0A
Other languages
English (en)
Inventor
Gilbert Lavielle
Bernard Cimetiere
Tony Verbeuren
Serge Simonet
Christine Vayssettes-Courchay
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of BR0202674A publication Critical patent/BR0202674A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Abstract

"COMPOSTOS DE BENZENOSSULFONAMIDA, PROCESSO PARA A SUA PREPARAçãO E COMPOSIçõES FARMACêUTICAS CONTENDO OS MESMOS". Composto de fórmula (I): em que: R~ a~ representa um grupo hidróxi, alcóxi, arilóxi ou arilalquilóxi, A representa um grupo CH ou um átomo de nitrogênio, em cujo caso R^ 1^ é como definido na descrição, ou R^ 1^-A juntos representam um átomo de oxigênio ou um grupo em que R^ 3^ e R^ 4^ São como definidos na descrição, R^ 2^ sendo um átomo de hidrogênio ou um grupo alquila, R~ b~ e R~ c~, os quais podem ser idênticos ou diferentes, cada um representa um átomo de hidrogênio, um átomo de halogênio, um grupo alquila, um grupo alcóxi, um grupo hidróxi ou um grupo trialoalquila, n é um número inteiro de 2 a 6 inclusive, m e p são números inteiros de O a 6 inclusive, Medicamentos.
BR0202674-0A 2001-07-13 2002-07-10 Compostos de benzenossulfonamida, processo para a sua preparação e composições farmacêuticas contendo os mesmos BR0202674A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0109338A FR2827287B1 (fr) 2001-07-13 2001-07-13 Nouveaux derives de benzene sulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
BR0202674A true BR0202674A (pt) 2003-05-06

Family

ID=8865461

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0202674-0A BR0202674A (pt) 2001-07-13 2002-07-10 Compostos de benzenossulfonamida, processo para a sua preparação e composições farmacêuticas contendo os mesmos

Country Status (18)

Country Link
US (1) US6589956B2 (pt)
EP (1) EP1275644A1 (pt)
JP (1) JP4138382B2 (pt)
KR (1) KR100498864B1 (pt)
CN (1) CN1168715C (pt)
AR (1) AR036340A1 (pt)
AU (1) AU2002300093B2 (pt)
BR (1) BR0202674A (pt)
CA (1) CA2394037C (pt)
EA (1) EA005403B1 (pt)
FR (1) FR2827287B1 (pt)
HK (1) HK1050681A1 (pt)
HU (1) HUP0202286A2 (pt)
MX (1) MXPA02006852A (pt)
NO (1) NO323868B1 (pt)
NZ (1) NZ520140A (pt)
PL (1) PL354948A1 (pt)
ZA (1) ZA200205598B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8097610B2 (en) * 2005-08-26 2012-01-17 Shionogi & Co., Ltd. Derivative having PPAR agonistic activity
WO2014047427A2 (en) 2012-09-21 2014-03-27 Vanderbilt University Substituted benzofuran, benzothiophene and indole mcl-1 inhibitors
US10005728B2 (en) 2013-08-28 2018-06-26 Vanderbilt University Substituted indole Mcl-1 inhibitors
US10533010B2 (en) 2014-03-27 2020-01-14 Vanderbilt University Substituted indole Mcl-1 inhibitors
US9949965B2 (en) 2014-10-17 2018-04-24 Vanderbilt University Tricyclic indole Mcl-1 inhibitors and uses thereof
EP3423435B1 (en) 2016-03-04 2023-08-23 Vanderbilt University Substituted indole mcl-1 inhibitors
EP4082616A4 (en) * 2019-12-24 2024-01-03 Sumitomo Pharma Co Ltd AMIDE DERIVATIVE OF ALIPHATIC ACID

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3468882A (en) * 1966-10-07 1969-09-23 Sterling Drug Inc Phenylhydrazone derivatives as intermediates for preparing indoles
GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
KR940007458B1 (ko) * 1991-11-21 1994-08-18 주식회사 금성사 박막 트랜지스터 제조 방법
TW219358B (pt) * 1991-12-20 1994-01-21 Hokuriku Pharmaceutical
AU5715494A (en) * 1992-12-21 1994-07-19 Taisho Pharmaceutical Co., Ltd. N-substituted indole derivative
GB9317764D0 (en) * 1993-08-26 1993-10-13 Pfizer Ltd Therapeutic compound
FR2712591B1 (fr) * 1993-11-19 1996-02-09 Pf Medicament Nouvelles arylpipérazines dérivées d'indole, leur préparation et leur utilisation thérapeutique.
KR100436812B1 (ko) * 1995-01-06 2004-08-31 도레이 가부시끼가이샤 벤젠축합헤테로환유도체및그유도체를유효성분으로함유하는의약조성물
AU7319096A (en) * 1995-11-02 1997-05-22 Merck Sharp & Dohme Limited Bicyclic heteroaryl-alkylene-(homo)piperazinones and thione analogues thereof, their preparation and their use as selective agonists of 5-ht1-like receptors
GB9523243D0 (en) * 1995-11-14 1996-01-17 Merck Sharp & Dohme Therapeutic agents
GB9523250D0 (en) * 1995-11-14 1996-01-17 Merck Sharp & Dohme Therapeutic agents

Also Published As

Publication number Publication date
CA2394037A1 (fr) 2003-01-13
JP2003064055A (ja) 2003-03-05
EP1275644A1 (fr) 2003-01-15
HUP0202286A2 (hu) 2003-08-28
FR2827287A1 (fr) 2003-01-17
AR036340A1 (es) 2004-09-01
NO20023389L (no) 2003-01-14
HK1050681A1 (en) 2003-07-04
CA2394037C (fr) 2008-04-29
KR20030007173A (ko) 2003-01-23
AU2002300093B2 (en) 2007-07-12
EA005403B1 (ru) 2005-02-24
JP4138382B2 (ja) 2008-08-27
CN1168715C (zh) 2004-09-29
US6589956B2 (en) 2003-07-08
PL354948A1 (en) 2003-01-27
ZA200205598B (en) 2003-03-27
US20030109533A1 (en) 2003-06-12
MXPA02006852A (es) 2005-07-25
NO20023389D0 (no) 2002-07-12
HU0202286D0 (pt) 2002-09-28
EA200200665A1 (ru) 2003-02-27
NZ520140A (en) 2003-09-26
FR2827287B1 (fr) 2003-10-31
KR100498864B1 (ko) 2005-07-04
NO323868B1 (no) 2007-07-16
CN1397550A (zh) 2003-02-19

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 8A. ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2103 DE 26/04/2011.