KR100498864B1 - 벤젠설폰아미드 화합물, 이들의 제조 방법 및 이들을함유하는 약제 조성물 - Google Patents

벤젠설폰아미드 화합물, 이들의 제조 방법 및 이들을함유하는 약제 조성물 Download PDF

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KR100498864B1
KR100498864B1 KR10-2002-0040945A KR20020040945A KR100498864B1 KR 100498864 B1 KR100498864 B1 KR 100498864B1 KR 20020040945 A KR20020040945 A KR 20020040945A KR 100498864 B1 KR100498864 B1 KR 100498864B1
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compound
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KR20030007173A (ko
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질베르 라비엘
베르나르드 시메티에르
토니 베르베렝
세르쥬 시모네
크리스틴 바이세트-쿠르샤이
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르 라보레또레 쎄르비에르
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
KR10-2002-0040945A 2001-07-13 2002-07-13 벤젠설폰아미드 화합물, 이들의 제조 방법 및 이들을함유하는 약제 조성물 Expired - Fee Related KR100498864B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0109338A FR2827287B1 (fr) 2001-07-13 2001-07-13 Nouveaux derives de benzene sulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR01.09338 2001-07-13

Publications (2)

Publication Number Publication Date
KR20030007173A KR20030007173A (ko) 2003-01-23
KR100498864B1 true KR100498864B1 (ko) 2005-07-04

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KR10-2002-0040945A Expired - Fee Related KR100498864B1 (ko) 2001-07-13 2002-07-13 벤젠설폰아미드 화합물, 이들의 제조 방법 및 이들을함유하는 약제 조성물

Country Status (17)

Country Link
US (1) US6589956B2 (enExample)
EP (1) EP1275644A1 (enExample)
JP (1) JP4138382B2 (enExample)
KR (1) KR100498864B1 (enExample)
CN (1) CN1168715C (enExample)
AR (1) AR036340A1 (enExample)
AU (1) AU2002300093B2 (enExample)
BR (1) BR0202674A (enExample)
CA (1) CA2394037C (enExample)
EA (1) EA005403B1 (enExample)
FR (1) FR2827287B1 (enExample)
HU (1) HUP0202286A2 (enExample)
MX (1) MXPA02006852A (enExample)
NO (1) NO323868B1 (enExample)
NZ (1) NZ520140A (enExample)
PL (1) PL354948A1 (enExample)
ZA (1) ZA200205598B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8097610B2 (en) * 2005-08-26 2012-01-17 Shionogi & Co., Ltd. Derivative having PPAR agonistic activity
WO2014047427A2 (en) 2012-09-21 2014-03-27 Vanderbilt University Substituted benzofuran, benzothiophene and indole mcl-1 inhibitors
EP3038618B1 (en) 2013-08-28 2020-10-14 Vanderbilt University Substituted indole mcl-1 inhibitors
JP6757312B2 (ja) 2014-03-27 2020-09-16 ヴァンダービルト ユニバーシティー 置換インドールｍｃｌ−１阻害剤
US9949965B2 (en) 2014-10-17 2018-04-24 Vanderbilt University Tricyclic indole Mcl-1 inhibitors and uses thereof
BR112018067775B1 (pt) 2016-03-04 2024-02-15 Vanderbilt University Compostos inibidores de mcl-1 indol substituídos, composição farmacêutica compreendendo ditos compostos e usos terapêuticos dos mesmos
MX2022007947A (es) * 2019-12-24 2022-07-27 Sumitomo Pharma Co Ltd Derivado de amida de acido alifatico.

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR860001788A (ko) * 1984-08-01 1986-03-22 베리 앤소니 뉴샘 인돌 유도체의 제조방법
KR930011299A (ko) * 1991-11-21 1993-06-24 이헌조 박막 트랜지스터 제조방법
WO1994014769A1 (fr) * 1992-12-21 1994-07-07 Taisho Pharmaceutical Co., Ltd. Derive indolique a substitution n
US5726177A (en) * 1993-11-19 1998-03-10 Pierre Fabre Medicament Indole-derived arylpiperazines as ligands for 5HT1 -like, 5HT1B and 5HT1D receptors
US5744488A (en) * 1993-08-26 1998-04-28 Pfizer Inc. Indole derivatives thromboxane A2 antagonists

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3468882A (en) * 1966-10-07 1969-09-23 Sterling Drug Inc Phenylhydrazone derivatives as intermediates for preparing indoles
TW219358B (enExample) * 1991-12-20 1994-01-21 Hokuriku Pharmaceutical
FI963477A7 (fi) * 1995-01-06 1996-11-04 Toray Industries Benseenin kanssa renkaaksi suljettu heterosyklinen johdannainen
US5998415A (en) * 1995-11-02 1999-12-07 Merck Sharp & Dohme Ltd. Bicyclic heteroaryl-alkylene-(homo)piperazinones and thione analogues thereof, their preparation, and their use of as selective agonists of 5-HT1 -like receptors
GB9523243D0 (en) * 1995-11-14 1996-01-17 Merck Sharp & Dohme Therapeutic agents
GB9523250D0 (en) * 1995-11-14 1996-01-17 Merck Sharp & Dohme Therapeutic agents

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR860001788A (ko) * 1984-08-01 1986-03-22 베리 앤소니 뉴샘 인돌 유도체의 제조방법
KR930011299A (ko) * 1991-11-21 1993-06-24 이헌조 박막 트랜지스터 제조방법
WO1994014769A1 (fr) * 1992-12-21 1994-07-07 Taisho Pharmaceutical Co., Ltd. Derive indolique a substitution n
US5744488A (en) * 1993-08-26 1998-04-28 Pfizer Inc. Indole derivatives thromboxane A2 antagonists
US5726177A (en) * 1993-11-19 1998-03-10 Pierre Fabre Medicament Indole-derived arylpiperazines as ligands for 5HT1 -like, 5HT1B and 5HT1D receptors

Also Published As

Publication number Publication date
HUP0202286A2 (hu) 2003-08-28
CA2394037A1 (fr) 2003-01-13
CA2394037C (fr) 2008-04-29
JP4138382B2 (ja) 2008-08-27
ZA200205598B (en) 2003-03-27
AU2002300093B2 (en) 2007-07-12
JP2003064055A (ja) 2003-03-05
EP1275644A1 (fr) 2003-01-15
CN1397550A (zh) 2003-02-19
KR20030007173A (ko) 2003-01-23
EA200200665A1 (ru) 2003-02-27
AR036340A1 (es) 2004-09-01
HU0202286D0 (enExample) 2002-09-28
PL354948A1 (en) 2003-01-27
EA005403B1 (ru) 2005-02-24
FR2827287A1 (fr) 2003-01-17
BR0202674A (pt) 2003-05-06
NO20023389L (no) 2003-01-14
CN1168715C (zh) 2004-09-29
MXPA02006852A (es) 2005-07-25
NZ520140A (en) 2003-09-26
HK1050681A1 (en) 2003-07-04
NO20023389D0 (no) 2002-07-12
FR2827287B1 (fr) 2003-10-31
US6589956B2 (en) 2003-07-08
US20030109533A1 (en) 2003-06-12
NO323868B1 (no) 2007-07-16

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