CN115667212A - 高纯度的n-(5-甲氧基-2-苯氧基苯基)甲磺酰胺及其制造方法 - Google Patents

高纯度的n-(5-甲氧基-2-苯氧基苯基)甲磺酰胺及其制造方法 Download PDF

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Publication number
CN115667212A
CN115667212A CN202180038860.2A CN202180038860A CN115667212A CN 115667212 A CN115667212 A CN 115667212A CN 202180038860 A CN202180038860 A CN 202180038860A CN 115667212 A CN115667212 A CN 115667212A
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CN
China
Prior art keywords
methoxy
compound
phenoxyphenyl
methanesulfonamide
solvent
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CN202180038860.2A
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English (en)
Chinese (zh)
Inventor
长远裕介
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Toyama Chemical Co Ltd
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Toyama Chemical Co Ltd
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Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of CN115667212A publication Critical patent/CN115667212A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/38—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reaction of ammonia or amines with sulfonic acids, or with esters, anhydrides, or halides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/42—Separation; Purification; Stabilisation; Use of additives
    • C07C303/44—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202180038860.2A 2020-05-29 2021-05-28 高纯度的n-(5-甲氧基-2-苯氧基苯基)甲磺酰胺及其制造方法 Pending CN115667212A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020093975 2020-05-29
JP2020-093975 2020-05-29
PCT/JP2021/020368 WO2021241725A1 (ja) 2020-05-29 2021-05-28 高純度のｎ－（５－メトキシ―２－フェノキシフェニル）メタンスルホンアミド及びその製造方法

Publications (1)

Publication Number Publication Date
CN115667212A true CN115667212A (zh) 2023-01-31

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CN202180038860.2A Pending CN115667212A (zh) 2020-05-29 2021-05-28 高纯度的n-(5-甲氧基-2-苯氧基苯基)甲磺酰胺及其制造方法

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Country Link
JP (1) JP7453365B2 (https=)
CN (1) CN115667212A (https=)
WO (1) WO2021241725A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117185939A (zh) * 2023-09-13 2023-12-08 佳尔科生物科技南通有限公司 一种艾拉莫德中间体的制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0249778A (ja) * 1987-10-08 1990-02-20 Toyama Chem Co Ltd ４ｈ―１―ベンゾピラン―４―オン誘導体およびその塩、それらの製造法並びにそれらを含有する抗炎症剤
CN102807515A (zh) * 2012-09-04 2012-12-05 江苏昊华精细化工有限公司 3-甲磺酰胺基-4-苯氧基-6-（n-甲酰）胺基乙酰基苯酚的合成方法
CN103508927A (zh) * 2012-06-25 2014-01-15 天津药物研究院 一种2-甲磺酰氨基二苯醚的制备方法
CN107021891A (zh) * 2017-04-24 2017-08-08 常州佳德医药科技有限公司 一种艾拉莫德中间体的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL86462A (en) * 1987-05-29 1992-12-01 Fujisawa Pharmaceutical Co Alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same
TW200745096A (en) 2005-08-23 2007-12-16 Organon Nv Indole derivatives
MX2012009851A (es) 2010-02-26 2012-09-12 Boehringer Ingelheim Int Tienopirimidinas que contienen un grupo alquilo sustituido para composiciones farmaceuticas.
GB201601301D0 (en) 2016-01-25 2016-03-09 Takeda Pharmaceutical Novel compounds
CN106986797B (zh) * 2017-04-24 2018-09-28 常州佳德医药科技有限公司 N-(2-(4-乙酰苯氧基)-5-甲氧基苯基)甲磺酰胺及其制备方法
CN109400507A (zh) 2018-10-09 2019-03-01 常州工程职业技术学院 艾拉莫德中间体杂质的合成
WO2021020481A1 (ja) * 2019-07-29 2021-02-04 株式会社トクヤマ イグラチモド誘導体の中間体の製造方法、イグラチモドの製造方法、並びに新規結晶構造を有するイグラチモド及びその製造方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0249778A (ja) * 1987-10-08 1990-02-20 Toyama Chem Co Ltd ４ｈ―１―ベンゾピラン―４―オン誘導体およびその塩、それらの製造法並びにそれらを含有する抗炎症剤
CN103508927A (zh) * 2012-06-25 2014-01-15 天津药物研究院 一种2-甲磺酰氨基二苯醚的制备方法
CN102807515A (zh) * 2012-09-04 2012-12-05 江苏昊华精细化工有限公司 3-甲磺酰胺基-4-苯氧基-6-（n-甲酰）胺基乙酰基苯酚的合成方法
CN107021891A (zh) * 2017-04-24 2017-08-08 常州佳德医药科技有限公司 一种艾拉莫德中间体的制备方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117185939A (zh) * 2023-09-13 2023-12-08 佳尔科生物科技南通有限公司 一种艾拉莫德中间体的制备方法

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JPWO2021241725A1 (https=) 2021-12-02
WO2021241725A1 (ja) 2021-12-02

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