CN115252910A - 脂肪组织产品以及产生方法 - Google Patents

脂肪组织产品以及产生方法 Download PDF

Info

Publication number
CN115252910A
CN115252910A CN202210669481.XA CN202210669481A CN115252910A CN 115252910 A CN115252910 A CN 115252910A CN 202210669481 A CN202210669481 A CN 202210669481A CN 115252910 A CN115252910 A CN 115252910A
Authority
CN
China
Prior art keywords
tissue
matrix
adipose tissue
particles
adipose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202210669481.XA
Other languages
English (en)
Chinese (zh)
Inventor
辉·许
方弘
姆里纳尔·沙阿
伊瑟烈·詹姆斯·杰瑟普
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LifeCell Corp
Original Assignee
LifeCell Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LifeCell Corp filed Critical LifeCell Corp
Publication of CN115252910A publication Critical patent/CN115252910A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/04—Materials or treatment for tissue regeneration for mammary reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
CN202210669481.XA 2017-10-18 2018-10-18 脂肪组织产品以及产生方法 Pending CN115252910A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762573892P 2017-10-18 2017-10-18
US62/573,892 2017-10-18
CN201880065592.1A CN111201046B (zh) 2017-10-18 2018-10-18 脂肪组织产品以及产生方法
PCT/US2018/056473 WO2019079570A1 (en) 2017-10-18 2018-10-18 ADIPOSE TISSUE PRODUCTS AND METHODS OF PRODUCTION

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201880065592.1A Division CN111201046B (zh) 2017-10-18 2018-10-18 脂肪组织产品以及产生方法

Publications (1)

Publication Number Publication Date
CN115252910A true CN115252910A (zh) 2022-11-01

Family

ID=64267918

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202210669481.XA Pending CN115252910A (zh) 2017-10-18 2018-10-18 脂肪组织产品以及产生方法
CN201880065592.1A Active CN111201046B (zh) 2017-10-18 2018-10-18 脂肪组织产品以及产生方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201880065592.1A Active CN111201046B (zh) 2017-10-18 2018-10-18 脂肪组织产品以及产生方法

Country Status (7)

Country Link
US (3) US10821205B2 (https=)
EP (2) EP4541385A3 (https=)
JP (4) JP7297739B2 (https=)
CN (2) CN115252910A (https=)
AU (3) AU2018351051A1 (https=)
CA (1) CA3075099A1 (https=)
WO (1) WO2019079570A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150037436A1 (en) 2013-07-30 2015-02-05 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
CN115252910A (zh) * 2017-10-18 2022-11-01 生命细胞公司 脂肪组织产品以及产生方法
US11123375B2 (en) 2017-10-18 2021-09-21 Lifecell Corporation Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products
US11246994B2 (en) 2017-10-19 2022-02-15 Lifecell Corporation Methods for introduction of flowable acellular tissue matrix products into a hand
WO2019079672A1 (en) 2017-10-19 2019-04-25 Lifecell Corporation ACELLULAR TISSUE MATRIX PRODUCTS FLUIDS AND METHODS OF PRODUCTION
MX2021014654A (es) * 2019-05-30 2022-03-11 Lifecell Corp Implante de mama biologico.
WO2021003321A1 (en) * 2019-07-03 2021-01-07 Lifecell Corporation Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products
US20210052774A1 (en) * 2019-08-21 2021-02-25 Lifecell Corporation Fixed-shape tissue matrix and related methods
US20230044236A1 (en) * 2019-12-17 2023-02-09 L&C Bio Co., Ltd. Medical Composition Comprising Adipose Tissue-Derived Extracellular Matrix And Method For Preparing Same
KR102433259B1 (ko) * 2019-12-17 2022-08-17 주식회사 엘앤씨바이오 지방조직 유래 세포외기질을 포함하는 의료용 조성물 및 그 제조방법
US20250332250A1 (en) * 2020-10-23 2025-10-30 Sk Bioscience Co., Ltd. Vaccine composition or kit for reducing size or volume of target tissue, containing genetic material that encodes foreign antigen
EP4052734B1 (en) * 2021-03-02 2024-04-24 Solidified Inc. Immunocompatible tissue scaffold and methods of forming the same
US12351621B1 (en) 2023-05-03 2025-07-08 Humabiologics, Inc. Composite collagen product and method of making thereof
US12134792B1 (en) 2023-05-03 2024-11-05 Humabiologics, Inc. Process for production of a soluble and insoluble collagen product from mammalian dermis tissue
US12351620B1 (en) 2023-05-03 2025-07-08 Humabiologics, Inc. Process for production of a soluble and insoluble collagen product from mammalian dermis tissue

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101161298A (zh) * 2007-11-20 2008-04-16 郑隆泗 一种以明胶为原料制备明胶海绵颗粒栓塞剂的工艺
CN101574539A (zh) * 2009-06-15 2009-11-11 北京大学 一种明胶海绵及其制备方法
CN101991875A (zh) * 2010-10-29 2011-03-30 上海硅健生物材料有限公司 介孔生物活性玻璃和壳聚糖复合多孔止血材料及制备方法
CN102575229A (zh) * 2009-08-11 2012-07-11 约翰霍普金斯大学 用于植入经加工的脂肪组织和经加工的脂肪组织产品的组合物和方法

Family Cites Families (146)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1562244A (en) 1976-11-11 1980-03-05 Lock P M Wound dressing materials
US4569348A (en) 1980-02-22 1986-02-11 Velcro Usa Inc. Catheter tube holder strap
US4373519A (en) 1981-06-26 1983-02-15 Minnesota Mining And Manufacturing Company Composite wound dressing
US4582640A (en) 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
MX163953B (es) 1984-03-27 1992-07-03 Univ New Jersey Med Procedimiento para preparar una matriz biodegradable a base de colageno
US4969912A (en) 1988-02-18 1990-11-13 Kelman Charles D Human collagen processing and autoimplant use
US5024841A (en) 1988-06-30 1991-06-18 Collagen Corporation Collagen wound healing matrices and process for their production
US4950483A (en) 1988-06-30 1990-08-21 Collagen Corporation Collagen wound healing matrices and process for their production
US4902508A (en) 1988-07-11 1990-02-20 Purdue Research Foundation Tissue graft composition
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
WO1991006568A1 (en) 1988-11-07 1991-05-16 Synergen, Inc. High molecular weight human angiogenic factors
JP2719671B2 (ja) 1989-07-11 1998-02-25 日本ゼオン株式会社 創傷被覆材
US5290558A (en) 1989-09-21 1994-03-01 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
US5131850A (en) 1989-11-03 1992-07-21 Cryolife, Inc. Method for cryopreserving musculoskeletal tissues
US5104957A (en) 1990-02-28 1992-04-14 Autogenesis Technologies, Inc. Biologically compatible collagenous reaction product and articles useful as medical implants produced therefrom
US5336616A (en) 1990-09-12 1994-08-09 Lifecell Corporation Method for processing and preserving collagen-based tissues for transplantation
US8067149B2 (en) 1990-09-12 2011-11-29 Lifecell Corporation Acellular dermal matrix and method of use thereof for grafting
CA2051092C (en) 1990-09-12 2002-07-23 Stephen A. Livesey Method and apparatus for cryopreparation, dry stabilization and rehydration of biological suspensions
US5231169A (en) 1990-10-17 1993-07-27 Norian Corporation Mineralized collagen
US5263971A (en) 1991-02-13 1993-11-23 Life Medical Sciences, Inc. Apparatus for the closure of wide skin defects by stretching of skin
US5254133A (en) 1991-04-24 1993-10-19 Seid Arnold S Surgical implantation device and related method of use
US5149331A (en) 1991-05-03 1992-09-22 Ariel Ferdman Method and device for wound closure
US5160313A (en) 1991-05-14 1992-11-03 Cryolife, Inc. Process for preparing tissue for transplantation
US5636643A (en) 1991-11-14 1997-06-10 Wake Forest University Wound treatment employing reduced pressure
US5645081A (en) 1991-11-14 1997-07-08 Wake Forest University Method of treating tissue damage and apparatus for same
US7198046B1 (en) 1991-11-14 2007-04-03 Wake Forest University Health Sciences Wound treatment employing reduced pressure
US5275826A (en) 1992-11-13 1994-01-04 Purdue Research Foundation Fluidized intestinal submucosa and its use as an injectable tissue graft
US5641518A (en) 1992-11-13 1997-06-24 Purdue Research Foundation Method of repairing bone tissue
US5437651A (en) 1993-09-01 1995-08-01 Research Medical, Inc. Medical suction apparatus
US5549584A (en) 1994-02-14 1996-08-27 The Kendall Company Apparatus for removing fluid from a wound
WO1995024873A1 (en) 1994-03-14 1995-09-21 Cryolife, Inc. Treated tissue for implantation and preparation methods
US5489304A (en) 1994-04-19 1996-02-06 Brigham & Women's Hospital Method of skin regeneration using a collagen-glycosaminoglycan matrix and cultured epithelial autograft
US5906827A (en) 1994-06-03 1999-05-25 Creative Biomolecules, Inc. Matrix for the manufacture of autogenous replacement body parts
US5599852A (en) 1994-10-18 1997-02-04 Ethicon, Inc. Injectable microdispersions for soft tissue repair and augmentation
US5622867A (en) 1994-10-19 1997-04-22 Lifecell Corporation Prolonged preservation of blood platelets
US6485723B1 (en) 1995-02-10 2002-11-26 Purdue Research Foundation Enhanced submucosal tissue graft constructs
US5834232A (en) 1996-05-01 1998-11-10 Zymogenetics, Inc. Cross-linked gelatin gels and methods of making them
US6666892B2 (en) 1996-08-23 2003-12-23 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
US6066325A (en) 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US8603511B2 (en) * 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
WO1998019719A1 (en) 1996-11-05 1998-05-14 Purdue Research Foundation Myocardial graft constructs
US6998418B1 (en) 1996-11-05 2006-02-14 Gp Medical, Inc. Acellular biological material chemically treated with genipin
AUPO599897A0 (en) 1997-04-03 1997-05-01 Vidal, Linus Clear collagen for facial implants
US5993844A (en) 1997-05-08 1999-11-30 Organogenesis, Inc. Chemical treatment, without detergents or enzymes, of tissue to form an acellular, collagenous matrix
US6135116A (en) 1997-07-28 2000-10-24 Kci Licensing, Inc. Therapeutic method for treating ulcers
US6613278B1 (en) 1998-11-13 2003-09-02 Regeneration Technologies, Inc. Tissue pooling process
GB9719520D0 (en) 1997-09-12 1997-11-19 Kci Medical Ltd Surgical drape and suction heads for wound treatment
US6371992B1 (en) 1997-12-19 2002-04-16 The Regents Of The University Of California Acellular matrix grafts: preparation and use
US6071267A (en) 1998-02-06 2000-06-06 Kinetic Concepts, Inc. Medical patient fluid management interface system and method
US6326018B1 (en) 1998-02-27 2001-12-04 Musculoskeletal Transplant Foundation Flexible sheet of demineralized bone
US20030039678A1 (en) 1998-03-16 2003-02-27 Stone Kevin R. Xenograft bone matrix for orthopedic applications
US6179872B1 (en) 1998-03-17 2001-01-30 Tissue Engineering Biopolymer matt for use in tissue repair and reconstruction
US6432710B1 (en) 1998-05-22 2002-08-13 Isolagen Technologies, Inc. Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
ES2257050T3 (es) 1998-05-26 2006-07-16 Lifecell Corporation Conservacion por el frio de hematies humanos.
US6933326B1 (en) 1998-06-19 2005-08-23 Lifecell Coporation Particulate acellular tissue matrix
CA2335686C (en) 1998-06-19 2008-11-18 Lifecell Corporation Particulate acellular tissue matrix
WO2000016822A1 (en) 1998-09-21 2000-03-30 The Brigham And Women's Hospital, Inc. Compositions and methods for tissue repair
US6565874B1 (en) 1998-10-28 2003-05-20 Atrix Laboratories Polymeric delivery formulations of leuprolide with improved efficacy
WO2000047114A1 (en) 1999-02-12 2000-08-17 Collagenesis, Inc. Injectable collagen-based delivery system for bone morphogenic proteins
US6856821B2 (en) 2000-05-26 2005-02-15 Kci Licensing, Inc. System for combined transcutaneous blood gas monitoring and vacuum assisted wound closure
US6599318B1 (en) 1999-11-30 2003-07-29 Shlomo Gabbay Implantable support apparatus and method of using same
US6576265B1 (en) 1999-12-22 2003-06-10 Acell, Inc. Tissue regenerative composition, method of making, and method of use thereof
AU9109201A (en) 2000-09-18 2002-03-26 Organogenesis Inc Methods for treating a patient using a bioengineered flat sheet graft prostheses
IL139708A0 (en) 2000-11-15 2002-02-10 Amiel Gilad Process of decellularizing biological matrices and acellular biological matrices useful in tissue engineering
US7763769B2 (en) 2001-02-16 2010-07-27 Kci Licensing, Inc. Biocompatible wound dressing
US7700819B2 (en) 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
US7070584B2 (en) 2001-02-20 2006-07-04 Kci Licensing, Inc. Biocompatible wound dressing
AU2002329884A1 (en) 2001-08-27 2003-03-10 Regeneration Technologies, Inc. Processed soft tissue for topical or internal application
WO2003032735A1 (en) 2001-10-18 2003-04-24 Lifecell Corporation Remodeling of tissues and organs
JP4489437B2 (ja) 2002-02-21 2010-06-23 エンセル，インコーポレイテッド 表面コーティングとしての固定化生物活性ヒドロゲルマトリックス
WO2003080119A1 (en) 2002-03-26 2003-10-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Responsive biomedical composites
US20030225347A1 (en) 2002-06-03 2003-12-04 Argenta Louis C. Directed tissue growth employing reduced pressure
US7498040B2 (en) 2005-10-12 2009-03-03 Lifenet Health Compositions for repair of defects in osseous tissues, and methods of making the same
US20040037735A1 (en) 2002-08-23 2004-02-26 Depaula Carl Alexander Allograft tissue purification process for cleaning bone
US7402319B2 (en) 2002-09-27 2008-07-22 Board Of Regents, The University Of Texas System Cell-free tissue replacement for tissue engineering
US6840960B2 (en) 2002-09-27 2005-01-11 Stephen K. Bubb Porous implant system and treatment method
US7824701B2 (en) 2002-10-18 2010-11-02 Ethicon, Inc. Biocompatible scaffold for ligament or tendon repair
US7115100B2 (en) 2002-11-15 2006-10-03 Ethicon, Inc. Tissue biopsy and processing device
FR2856305B1 (fr) 2003-06-19 2007-08-24 Inst Nat Sante Rech Med Protheses avec revetements biologiquement actifs
WO2005001080A2 (en) 2003-06-27 2005-01-06 Ethicon, Incorporated Postpartum-derived cells for use in treatment of disease of the heart and circulatory system
CA2533259C (en) 2003-07-21 2014-01-28 Lifecell Corporation Acellular tissue matrices made from galactose .alpha.-1,3-galactose-deficient tissue
US7901461B2 (en) 2003-12-05 2011-03-08 Ethicon, Inc. Viable tissue repair implants and methods of use
AU2005223617A1 (en) 2004-03-17 2005-09-29 Revivicor, Inc. Tissue products from animals lacking functional alpha 1,3 galactosyl transferase
KR100680134B1 (ko) 2004-06-10 2007-02-08 박우삼 무세포 진피를 주사가능하도록 입자 형태로 가공한 필러
US20060058892A1 (en) 2004-09-16 2006-03-16 Lesh Michael D Valved tissue augmentation implant
US20060073592A1 (en) 2004-10-06 2006-04-06 Wendell Sun Methods of storing tissue matrices
US7905826B2 (en) 2004-11-03 2011-03-15 Cook Incorporated Methods for modifying vascular vessel walls
DE102005002644A1 (de) 2005-01-19 2006-07-20 Schülke & Mayr GmbH Zusammensetzungen für die hygienische Händedesinfektion und die desinfizierende Händewaschung
EP1887967A2 (en) 2005-04-25 2008-02-20 Eric F. Bernstein Dermal fillers for biomedical applications in mammals and methods of using the same
JP5478884B2 (ja) 2005-09-26 2014-04-23 ライフセル コーポレーション 乾燥血小板組成物
US7498041B2 (en) 2005-10-12 2009-03-03 Lifenet Health Composition for repair of defects in osseous tissues
JP5002805B2 (ja) 2005-10-14 2012-08-15 財団法人ヒューマンサイエンス振興財団 生物由来スキャフォールドの作製方法
US9456860B2 (en) 2006-03-14 2016-10-04 Kci Licensing, Inc. Bioresorbable foaming tissue dressing
US8267918B2 (en) 2006-03-14 2012-09-18 Kci Licensing, Inc. System and method for percutaneously administering reduced pressure treatment using a flowable manifold
US20070248575A1 (en) 2006-04-19 2007-10-25 Jerome Connor Bone graft composition
EP2021536B1 (en) 2006-04-24 2014-02-26 Coloplast A/S Non-woven structures produced by a non-toxic dry solvent spinning process
EP2015707B1 (en) 2006-05-09 2019-01-23 LifeCell Corporation Reinforced biological tissue
JP5050197B2 (ja) 2006-07-31 2012-10-17 財団法人ヒューマンサイエンス振興財団 生物由来スキャフォールドの作製方法
TWI362925B (en) 2006-11-09 2012-05-01 Kci Licensing Inc Method for preparing a bioresorbable dressing comprising bioresorbable microparticles and method for preparing a bioresorbable dressing comprising bioresorbable microspheres
CA2682034C (en) * 2007-03-26 2015-01-27 Baxter International Inc. Injectable void filler for soft tissue augmentation
JP2010524644A (ja) 2007-04-26 2010-07-22 アドバンスト・テクノロジーズ・アンド・リジェネレイティブ・メディスン・エルエルシー 内腔器官用の組織工学装置及び方法
US9034367B2 (en) 2007-05-10 2015-05-19 Cormatrix Cardiovascular, Inc. Articles for tissue regeneration with biodegradable polymer
MX2009013767A (es) 2007-06-29 2010-01-26 Kci Licensing Inc Activacion de la formacion de hueso y cartilago.
ES2840251T3 (es) 2007-07-10 2021-07-06 Lifecell Corp Composiciones acelulares de matriz tisular para reparación de tejidos
US20090024224A1 (en) 2007-07-16 2009-01-22 Chen Silvia S Implantation of cartilage
US9161970B2 (en) * 2007-12-12 2015-10-20 Allergan, Inc. Dermal filler
US9782300B2 (en) 2008-02-01 2017-10-10 Kci Licensing, Inc. Fiber-microsphere bioresorbable composite scaffold for wound healing
JP5290405B2 (ja) 2008-05-13 2013-09-18 ケーシーアイ ライセンシング インコーポレイテッド カテーテル／フィラメント型装置および皮膚表面下の傷を治療する方法
CA2726350C (en) 2008-06-06 2016-07-19 Lifecell Corporation Elastase treatment of tissue matrices
CN102123747B (zh) 2008-06-25 2015-10-14 凯希特许有限公司 可吸收减压歧管和系统
KR20110022706A (ko) 2008-06-26 2011-03-07 케이씨아이 라이센싱 인코포레이티드 감압 치료 및 연골세포를 사용한 연골 형성의 자극
EP2319548B1 (en) 2008-08-14 2016-06-01 KCI Licensing, Inc. Tissue scaffolds
US7927414B2 (en) 2008-09-05 2011-04-19 Ethicon, Inc. Method of manufacturing acellular matrix glue
EP2349089A4 (en) 2008-11-21 2014-01-15 Lifecell Corp REINFORCED BIOLOGICAL MATERIAL
CN102264430B (zh) 2008-12-31 2013-01-23 凯希特许有限公司 用于产生流体流动以刺激组织生长的系统
JP5643224B2 (ja) 2008-12-31 2014-12-17 ケーシーアイ ライセンシング インコーポレイテッド 組織に流体フローを提供するシステム
CN102264405B (zh) 2008-12-31 2013-07-03 凯希特许有限公司 用于向神经组织提供流体流的系统
AU2010249805B2 (en) 2009-05-20 2015-06-11 Humacyte, Inc. Elastin for soft tissue augmentation
MX2012006759A (es) * 2009-12-17 2012-07-30 Univ Kingston Tejido adiposo descelularizado.
JP5818372B2 (ja) 2010-01-22 2015-11-18 ケーシーアイ ライセンシング インク 陰圧創傷療法に関する発泡流体灌注デバイス、システムおよび方法
US8632512B2 (en) 2010-04-09 2014-01-21 Kci Licensing, Inc. Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds
AU2011276246B2 (en) 2010-07-08 2014-12-04 Lifecell Corporation Method for shaping tissue matrices
EP3597226A1 (en) 2010-08-10 2020-01-22 Lifecell Corporation Regenerative tissue scaffolds
CN102068714A (zh) * 2011-01-19 2011-05-25 北京大学 一种胶原海绵及其制备方法
EP2696908B1 (en) 2011-04-14 2015-03-11 Lifecell Corporation Regenerative materials
US20140271454A1 (en) * 2011-04-21 2014-09-18 Cytograft Tissue Engineering, Inc. Cell-synthesized particles
EP3851131A1 (en) 2011-05-31 2021-07-21 LifeCell Corporation Adipose tissue matrices
DK2766056T3 (en) 2011-10-11 2017-08-21 Allergan Holdings France S A S THREAD OF THE CROSS-LOWER HYALURONIC ACID AND PROCEDURES FOR USING IT
JP6362540B2 (ja) * 2011-11-09 2018-07-25 トラスティーズ・オブ・タフツ・カレッジＴｒｕｓｔｅｅｓ Ｏｆ Ｔｕｆｔｓ Ｃｏｌｌｅｇｅ 注射可能なシルクフィブロイン粒子およびその使用
US20130121970A1 (en) 2011-11-10 2013-05-16 Lifecell Corporation Method for elimination of space through tissue approximation
US9549805B2 (en) * 2011-12-20 2017-01-24 Lifecell Corporation Flowable tissue products
EP3842078A1 (en) 2011-12-20 2021-06-30 LifeCell Corporation Sheet tissue products
BR112014026090A8 (pt) 2012-04-24 2019-08-27 Lifecell Corp composição de matriz tecidual apta a fluir
US9999637B2 (en) 2012-04-24 2018-06-19 Lifecell Corporation Functionalized tissue matrices
EP2968417A4 (en) 2013-03-15 2016-09-14 Univ Leland Stanford Junior INJECTABLE COMPOSITION FOR IN-SITU REPAIR AND RE-GENERATION OF INJURED TAPES OR TONES AND METHODS OF USE
FR3006689A1 (fr) * 2013-06-11 2014-12-12 Benedicte Vincente Tauzin Procede de reticulation de l'acide hyaluronique; procede de preparation d'un hydrogel injectable; hydrogel obtenu; utilisation de l'hydroget obtenu
WO2015048317A1 (en) 2013-09-25 2015-04-02 The Children's Mercy Hospital Decellularized hyaline cartilage powder for tissue scaffolds
WO2016048946A1 (en) * 2014-09-25 2016-03-31 Acell, Inc. Porous foams derived from extracellular matrix, porous foam ecm medical devices, and methods of use and making thereof
KR101729127B1 (ko) * 2014-10-24 2017-04-26 주식회사 엘앤씨바이오 입자형 무세포 진피와 히알루론산이 전자빔을 통해 물리적으로 가교된 생체 이식용 조성물의 제조방법
US20170021058A1 (en) * 2015-07-24 2017-01-26 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
GB201514788D0 (en) 2015-08-20 2015-10-07 Ecole Polytech Malleable scaffold material and uses thereof
US20170224869A1 (en) 2016-02-08 2017-08-10 Lifecell Corporation Biologic breast implant
US11123375B2 (en) 2017-10-18 2021-09-21 Lifecell Corporation Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products
CN115252910A (zh) * 2017-10-18 2022-11-01 生命细胞公司 脂肪组织产品以及产生方法
WO2019079672A1 (en) 2017-10-19 2019-04-25 Lifecell Corporation ACELLULAR TISSUE MATRIX PRODUCTS FLUIDS AND METHODS OF PRODUCTION
US11246994B2 (en) 2017-10-19 2022-02-15 Lifecell Corporation Methods for introduction of flowable acellular tissue matrix products into a hand

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101161298A (zh) * 2007-11-20 2008-04-16 郑隆泗 一种以明胶为原料制备明胶海绵颗粒栓塞剂的工艺
CN101574539A (zh) * 2009-06-15 2009-11-11 北京大学 一种明胶海绵及其制备方法
CN102575229A (zh) * 2009-08-11 2012-07-11 约翰霍普金斯大学 用于植入经加工的脂肪组织和经加工的脂肪组织产品的组合物和方法
CN101991875A (zh) * 2010-10-29 2011-03-30 上海硅健生物材料有限公司 介孔生物活性玻璃和壳聚糖复合多孔止血材料及制备方法

Also Published As

Publication number Publication date
JP7785886B2 (ja) 2025-12-15
JP2025011092A (ja) 2025-01-23
JP7559144B2 (ja) 2024-10-01
CN111201046B (zh) 2022-06-28
US10821205B2 (en) 2020-11-03
JP7297739B2 (ja) 2023-06-26
US20210038767A1 (en) 2021-02-11
EP4541385A3 (en) 2025-06-25
AU2018351051A1 (en) 2020-03-19
AU2025263895A1 (en) 2025-12-04
EP3697460A1 (en) 2020-08-26
JP2021500091A (ja) 2021-01-07
EP4541385A2 (en) 2025-04-23
CN111201046A (zh) 2020-05-26
JP2026062652A (ja) 2026-04-10
US20190111183A1 (en) 2019-04-18
US20250065018A1 (en) 2025-02-27
CA3075099A1 (en) 2019-04-25
AU2024205150A1 (en) 2024-08-15
JP2023123578A (ja) 2023-09-05
WO2019079570A1 (en) 2019-04-25

Similar Documents

Publication Publication Date Title
CN111201046B (zh) 脂肪组织产品以及产生方法
Xia et al. Decellularized cartilage as a prospective scaffold for cartilage repair
US11123375B2 (en) Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products
US20240226375A1 (en) Flowable acellular tissue matrix products and methods of production
US20230211048A1 (en) Biologic breast implant
US11246994B2 (en) Methods for introduction of flowable acellular tissue matrix products into a hand
WO2021003321A1 (en) Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products
WO2021202965A1 (en) Adipose tissue matrix with tropoelastin

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination