CN114958772A - 端到端细胞治疗自动化 - Google Patents
端到端细胞治疗自动化 Download PDFInfo
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- CN114958772A CN114958772A CN202210735994.6A CN202210735994A CN114958772A CN 114958772 A CN114958772 A CN 114958772A CN 202210735994 A CN202210735994 A CN 202210735994A CN 114958772 A CN114958772 A CN 114958772A
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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- A61K40/00—Cellular immunotherapy
- A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
- A61K40/31—Chimeric antigen receptors [CAR]
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4202—Receptors, cell surface antigens or cell surface determinants
- A61K40/4203—Receptors for growth factors
- A61K40/4205—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ ErbB4
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C12M23/42—Integrated assemblies, e.g. cassettes or cartridges
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- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/20—Degassing; Venting; Bubble traps
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- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- A61K2239/59—Reproductive system, e.g. uterus, ovaries, cervix or testes
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- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C12N2501/51—B7 molecules, e.g. CD80, CD86, CD28 (ligand), CD152 (ligand)
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Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762553214P | 2017-09-01 | 2017-09-01 | |
| US62/553,214 | 2017-09-01 | ||
| US201862670391P | 2018-05-11 | 2018-05-11 | |
| US62/670,391 | 2018-05-11 | ||
| PCT/US2018/049171 WO2019046766A2 (en) | 2017-09-01 | 2018-08-31 | AUTOMATION OF CELLULAR THERAPY FROM END TO END |
| CN201880070590.1A CN111373030A (zh) | 2017-09-01 | 2018-08-31 | 端到端细胞治疗自动化 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880070590.1A Division CN111373030A (zh) | 2017-09-01 | 2018-08-31 | 端到端细胞治疗自动化 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114958772A true CN114958772A (zh) | 2022-08-30 |
Family
ID=63684512
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210735994.6A Pending CN114958772A (zh) | 2017-09-01 | 2018-08-31 | 端到端细胞治疗自动化 |
| CN201880070590.1A Pending CN111373030A (zh) | 2017-09-01 | 2018-08-31 | 端到端细胞治疗自动化 |
| CN202210736272.2A Pending CN115216450A (zh) | 2017-09-01 | 2018-08-31 | 端到端细胞治疗自动化 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880070590.1A Pending CN111373030A (zh) | 2017-09-01 | 2018-08-31 | 端到端细胞治疗自动化 |
| CN202210736272.2A Pending CN115216450A (zh) | 2017-09-01 | 2018-08-31 | 端到端细胞治疗自动化 |
Country Status (9)
| Country | Link |
|---|---|
| US (7) | US11447745B2 (enExample) |
| EP (1) | EP3662056A2 (enExample) |
| JP (5) | JP2020528284A (enExample) |
| KR (4) | KR102546681B1 (enExample) |
| CN (3) | CN114958772A (enExample) |
| AU (2) | AU2018324180B2 (enExample) |
| CA (3) | CA3248436A1 (enExample) |
| IL (2) | IL315340A (enExample) |
| WO (1) | WO2019046766A2 (enExample) |
Families Citing this family (84)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2520643B8 (en) | 2007-12-07 | 2019-11-27 | Miltenyi Biotec B.V. & Co. KG | Sample processing systems and methods |
| DK3256850T3 (da) | 2015-02-09 | 2025-08-18 | Slingshot Biosciences Inc | Hydrogelpartikler med justerbare optiske egenskaber og fremgangsmåder til anvendelse deraf |
| JP6987080B2 (ja) | 2016-05-05 | 2021-12-22 | サウスウェスト リサーチ インスティテュート | 細胞増殖のための三次元バイオリアクター及び関連用途 |
| US11590167B2 (en) | 2016-12-03 | 2023-02-28 | Juno Therapeutic, Inc. | Methods and compositions for use of therapeutic T cells in combination with kinase inhibitors |
| IL327498A (en) | 2017-06-02 | 2026-05-01 | Juno Therapeutics Inc | Articles of manufacture and methods for treatment using adoptive cell therapy |
| MX2019015505A (es) | 2017-06-30 | 2020-07-28 | Inscripta Inc | Metodos, modulos, instrumentos y sistemas de procesamiento de celulas automatizados. |
| EP3675835A4 (en) | 2017-08-28 | 2021-06-09 | Matthias Wagner | MICROFLUIDIC LASER ACTIVATED INTRACELLULAR DELIVERY SYSTEMS AND METHODS |
| KR102546681B1 (ko) * | 2017-09-01 | 2023-06-22 | 론차 콜로그네 게엠베하 | 엔드-투-엔드 세포 요법의 자동화 |
| US11932842B2 (en) | 2018-02-09 | 2024-03-19 | Global Life Sciences Solutions Usa Llc | Bioprocessing apparatus |
| US12252682B2 (en) | 2018-02-09 | 2025-03-18 | Global Life Sciences Solutions Usa Llc | System and method for fluid flow management in a bioprocessing system |
| US10889792B2 (en) | 2018-02-09 | 2021-01-12 | Global Life Sciences Solutions Usa Llc | Cell expansion vessel systems and methods |
| US11920119B2 (en) | 2018-02-09 | 2024-03-05 | Global Life Sciences Solutions Usa Llc | Systems and methods for bioprocessing |
| US12077743B2 (en) | 2018-02-09 | 2024-09-03 | Global Life Sciences Solutions Usa Llc | Apparatus for fluid line management in a bioprocessing system |
| US11371007B2 (en) | 2018-02-09 | 2022-06-28 | Global Life Sciences Solutions Usa Llc | System and method for fluid flow management in a bioprocessing system |
| US11414639B2 (en) | 2018-02-09 | 2022-08-16 | Global Life Sciences Solutions Usa Llc | Bioprocessing vessel |
| US11149244B2 (en) | 2018-04-04 | 2021-10-19 | Southwest Research Institute | Three-dimensional bioreactor for T-cell activation and expansion for immunotherapy |
| CA3100050A1 (en) * | 2018-05-11 | 2019-11-14 | Lupagen, Inc. | Systems and methods for closed loop, real-time modifications of patient cells |
| US11142740B2 (en) | 2018-08-14 | 2021-10-12 | Inscripta, Inc. | Detection of nuclease edited sequences in automated modules and instruments |
| US11447731B2 (en) | 2018-09-24 | 2022-09-20 | Southwest Research Institute | Three-dimensional bioreactors |
| EP3877748A4 (en) | 2018-11-06 | 2022-11-09 | Cellino Biotech, Inc. | Systems for cell control |
| JP2022008735A (ja) * | 2018-11-06 | 2022-01-14 | テルモ株式会社 | 細胞製造システム、細胞製造方法、医療装置及び医療デバイス |
| WO2020123649A1 (en) * | 2018-12-11 | 2020-06-18 | Lonza Walkersville, Inc. | Bedside automated cell engineering system and methods |
| JP7598864B2 (ja) | 2018-12-21 | 2024-12-12 | ロンザ ウォーカーズヴィル,インコーポレーテッド | ウイルスベクターの自動産生方法 |
| EP3898932A4 (en) * | 2018-12-21 | 2022-08-03 | Octane Biotech Inc. | CAROUSEL FOR MODULAR BIOLOGICAL PRODUCTION UNITS |
| IL284450B2 (en) | 2018-12-28 | 2026-04-01 | Octane Biotech Inc | Cell culture and tissue engineering systems with controlled environmental zones |
| SG11202108473XA (en) | 2019-02-08 | 2021-09-29 | Lonza Walkersville Inc | Cell concentration methods and devices for use in automated bioreactors |
| US12168087B2 (en) | 2019-03-05 | 2024-12-17 | Fenwal, Inc. | Collection, genome editing, and washing of T-cell lymphocytes |
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