CN114436893A - 一种氘代乙腈的生产工艺 - Google Patents
一种氘代乙腈的生产工艺 Download PDFInfo
- Publication number
- CN114436893A CN114436893A CN202210210567.6A CN202210210567A CN114436893A CN 114436893 A CN114436893 A CN 114436893A CN 202210210567 A CN202210210567 A CN 202210210567A CN 114436893 A CN114436893 A CN 114436893A
- Authority
- CN
- China
- Prior art keywords
- acetonitrile
- deuterated acetonitrile
- deuterated
- stirring
- production process
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000007960 acetonitrile Chemical class 0.000 title claims abstract description 35
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 16
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims abstract description 40
- 239000003054 catalyst Substances 0.000 claims abstract description 31
- 239000000047 product Substances 0.000 claims abstract description 25
- XLYOFNOQVPJJNP-ZSJDYOACSA-N Heavy water Chemical compound [2H]O[2H] XLYOFNOQVPJJNP-ZSJDYOACSA-N 0.000 claims abstract description 24
- 238000003756 stirring Methods 0.000 claims abstract description 21
- PBCJIPOGFJYBJE-UHFFFAOYSA-N acetonitrile;hydrate Chemical class O.CC#N PBCJIPOGFJYBJE-UHFFFAOYSA-N 0.000 claims abstract description 18
- 238000006243 chemical reaction Methods 0.000 claims abstract description 16
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims abstract description 11
- 229910052938 sodium sulfate Inorganic materials 0.000 claims abstract description 11
- 235000011152 sodium sulphate Nutrition 0.000 claims abstract description 11
- 239000007795 chemical reaction product Substances 0.000 claims abstract description 8
- 238000004821 distillation Methods 0.000 claims abstract description 8
- 239000000126 substance Substances 0.000 claims abstract description 3
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 claims description 28
- 229910000027 potassium carbonate Inorganic materials 0.000 claims description 14
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims description 11
- 229910052593 corundum Inorganic materials 0.000 claims description 11
- 229910001845 yogo sapphire Inorganic materials 0.000 claims description 11
- 238000001035 drying Methods 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 239000008367 deionised water Substances 0.000 claims description 7
- 229910021641 deionized water Inorganic materials 0.000 claims description 7
- 238000001354 calcination Methods 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims 1
- 238000010438 heat treatment Methods 0.000 abstract description 6
- 239000007788 liquid Substances 0.000 abstract description 5
- 238000003889 chemical engineering Methods 0.000 abstract description 2
- 239000012847 fine chemical Substances 0.000 abstract description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical class [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 230000032683 aging Effects 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 238000005481 NMR spectroscopy Methods 0.000 description 2
- 229910052783 alkali metal Inorganic materials 0.000 description 2
- 150000001340 alkali metals Chemical class 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 229910052805 deuterium Inorganic materials 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 238000003760 magnetic stirring Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 239000003960 organic solvent Substances 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- WEVYAHXRMPXWCK-FIBGUPNXSA-N acetonitrile-d3 Chemical compound [2H]C([2H])([2H])C#N WEVYAHXRMPXWCK-FIBGUPNXSA-N 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 239000000010 aprotic solvent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002431 foraging effect Effects 0.000 description 1
- 239000012074 organic phase Substances 0.000 description 1
- 238000006053 organic reaction Methods 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 229910001868 water Inorganic materials 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/32—Separation; Purification; Stabilisation; Use of additives
- C07C253/34—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/584—Recycling of catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
Abstract
Description
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202210210567.6A CN114436893B (zh) | 2022-03-04 | 2022-03-04 | 一种氘代乙腈的生产工艺 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202210210567.6A CN114436893B (zh) | 2022-03-04 | 2022-03-04 | 一种氘代乙腈的生产工艺 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN114436893A true CN114436893A (zh) | 2022-05-06 |
CN114436893B CN114436893B (zh) | 2024-03-19 |
Family
ID=81359464
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202210210567.6A Active CN114436893B (zh) | 2022-03-04 | 2022-03-04 | 一种氘代乙腈的生产工艺 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN114436893B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114773226A (zh) * | 2022-05-27 | 2022-07-22 | 安徽贵朋功能材料科技有限公司 | 一种用光电一体催化制备氘代乙腈的方法 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1394089A (en) * | 1971-07-29 | 1975-05-14 | Ca Atomic Energy Ltd | Hydrophobic support catalyst for h-d exchange |
US20130079554A1 (en) * | 2011-09-22 | 2013-03-28 | Ut-Battelle, Llc | Methods for the synthesis of deuterated acrylate salts |
CN110885985A (zh) * | 2019-12-05 | 2020-03-17 | 深圳大学 | 一种氘代化学品的制备方法 |
CN112409257A (zh) * | 2020-11-30 | 2021-02-26 | 天津阿尔塔科技有限公司 | 一种氘标记的去甲乌药碱稳定性同位素化合物的制备方法 |
CN114773226A (zh) * | 2022-05-27 | 2022-07-22 | 安徽贵朋功能材料科技有限公司 | 一种用光电一体催化制备氘代乙腈的方法 |
-
2022
- 2022-03-04 CN CN202210210567.6A patent/CN114436893B/zh active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1394089A (en) * | 1971-07-29 | 1975-05-14 | Ca Atomic Energy Ltd | Hydrophobic support catalyst for h-d exchange |
US20130079554A1 (en) * | 2011-09-22 | 2013-03-28 | Ut-Battelle, Llc | Methods for the synthesis of deuterated acrylate salts |
CN110885985A (zh) * | 2019-12-05 | 2020-03-17 | 深圳大学 | 一种氘代化学品的制备方法 |
CN112409257A (zh) * | 2020-11-30 | 2021-02-26 | 天津阿尔塔科技有限公司 | 一种氘标记的去甲乌药碱稳定性同位素化合物的制备方法 |
CN114773226A (zh) * | 2022-05-27 | 2022-07-22 | 安徽贵朋功能材料科技有限公司 | 一种用光电一体催化制备氘代乙腈的方法 |
Non-Patent Citations (1)
Title |
---|
余绍火等总编: "《中国粉体工业通鉴 2005版》", vol. 1, 西安地图出版社, pages: 197 - 198 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114773226A (zh) * | 2022-05-27 | 2022-07-22 | 安徽贵朋功能材料科技有限公司 | 一种用光电一体催化制备氘代乙腈的方法 |
CN114773226B (zh) * | 2022-05-27 | 2022-10-21 | 安徽贵朋功能材料科技有限公司 | 一种用光电一体催化制备氘代乙腈的方法 |
Also Published As
Publication number | Publication date |
---|---|
CN114436893B (zh) | 2024-03-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN1189242C (zh) | 一种颗粒型固体超强酸催化剂及制备方法 | |
CN113101914A (zh) | 一种碱性位点高分散、耐流失的单原子固体碱催化剂的制备方法和产品及其应用 | |
CN115646501B (zh) | 熔融盐法合成的钴单原子催化剂及其应用 | |
CN114436893A (zh) | 一种氘代乙腈的生产工艺 | |
CN105195188A (zh) | 镍-碳化钨/多孔碳纳米纤维复合催化剂及中间体与制备 | |
CN113751080B (zh) | 一种改性氧化铝载体及其制备方法和应用 | |
CN113058601B (zh) | 用于光解水催化制氢的三元复合催化剂的制备方法及应用 | |
CN108722486A (zh) | 一种窄带氮化碳修饰铁基金属有机骨架复合光催化剂的制备方法 | |
CN116003262B (zh) | 一种n,n-二甲基苯胺的合成方法 | |
CN110354882B (zh) | 一种BiVO4@ZnIn2S4/g-C3N4可见光响应光催化剂及其制备方法 | |
CN110327959B (zh) | 一种BiVO4@CdIn2S4/g-C3N4可见光响应光催化剂及其制备方法 | |
CN112354559A (zh) | 一种二维受体分子/多级孔TiO2复合光催化剂及其制备方法和光催化应用 | |
CN114849747B (zh) | 高岭土负载Keggin型杂多酸催化剂及制备和在甲基丙烯醛氧化中的应用 | |
CN111167443A (zh) | 一种新型钌基催化剂及其制备方法和应用 | |
CN114950561B (zh) | 一种co2光还原催化剂的制备方法 | |
CN114540840B (zh) | 一种FeCo/N-C纳米复合材料及其制备方法和应用 | |
CN114210351B (zh) | 一种硫酸乙烯酯合成用催化剂及硫酸乙烯酯合成方法 | |
CN105413728A (zh) | 一种与碳氮复合的二氧化钛中空微球及其制备方法 | |
CN110354883B (zh) | 一种BiVO4@CuIn2S4/g-C3N4可见光响应光催化剂及其制备方法 | |
CN102091647B (zh) | 磷酸盐修饰的小粒径NaY分子筛催化剂及其制法和用途 | |
CN104815639A (zh) | 一种生物柴油催化剂的制备方法 | |
CN113511637A (zh) | 一种双金属化合物/碳复合材料的制备方法 | |
CN113477266A (zh) | 一种Bi12O17Cl2/g-C3N4复合体系及其制备方法与应用 | |
CN110833845B (zh) | 一种固体碱催化剂的制备方法、固体碱催化剂及其应用 | |
CN109967085A (zh) | 一种催化燃烧含氯挥发性有机化合物的微纤复合分子筛膜催化剂及其制备方法与应用 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20240206 Address after: Room 2007, Incubation Building, Electronic Information Industry Park, No. 5 Jingwei Road, High tech Industrial Development Zone, Xuzhou City, Jiangsu Province, 221100 Applicant after: Juncheng (Xuzhou) New Materials Technology Co.,Ltd. Country or region after: China Address before: 272503 room 320, Jindu Xicheng, Yinsi Town, Wenshang County, Jining City, Shandong Province Applicant before: Shandong Hanfeng New Material Technology Co.,Ltd. Country or region before: China |
|
GR01 | Patent grant | ||
GR01 | Patent grant |