CN113925922A - Chinese patent medicine preparation for treating acute gastroenteritis - Google Patents
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Abstract
The invention discloses a Chinese patent medicine preparation for treating acute gastroenteritis, which is characterized by being prepared from the following components: semen litchi, radix aucklandiae, fructus Schisandrae chinensis, flos Sophorae Immaturus, Ginseng radix, rhizoma Dioscoreae and cortex Cinnamomi; the weight parts of the components are as follows: 8-12 parts of lychee seed, 5-8 parts of elecampane, 2-5 parts of schisandra chinensis, 1-3 parts of sophora flower, 3-6 parts of ginseng, 4-6 parts of Chinese yam and 2-4 parts of cinnamon. The invention also discloses a preparation method and an administration method of the Chinese patent medicine preparation for treating acute gastroenteritis. The Chinese patent medicine preparation for treating acute gastroenteritis, disclosed by the invention, has the advantages of obvious treatment effect on acute gastroenteritis, no toxic or side effect, few and refined prescription medicines, safety in use and convenience in taking.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a Chinese patent medicine preparation for treating acute gastroenteritis.
Background
In recent years, with the acceleration of the pace of life and the increase of the pressure of life and work, the incidence of acute gastroenteritis is one of common clinical diseases and tends to increase year by year. The disease is most frequently seen in summer and autumn, and is usually caused by acute inflammatory changes of gastrointestinal mucosa due to improper diet or food containing pathogenic bacteria and toxins thereof. The clinical manifestations mainly include nausea, vomiting, abdominal pain, diarrhea, fever, etc., and severe cases may cause dehydration, electrolyte disturbance, shock bowel perforation, septicemia, etc. Seriously affecting the normal life of the patients and bringing endless pain to the patients. Therefore, the development of the medicine for treating the acute gastroenteritis is important for the immediate targeted treatment of the acute gastroenteritis.
At present, the clinical treatment methods of acute gastroenteritis are many, antibiotics, gastrointestinal mucosa protective agents and the like are selected, however, the side effects of the medicaments are relatively large, certain stimulation is caused to the stomach and the body, the health of the patient is extremely bad, and the curative effect is poor. Under the situation, the Chinese patent medicine for treating acute gastroenteritis is produced at the same time, and the medicine is widely favored by people due to the characteristics of small side effect and good curative effect.
The existing Chinese patent medicines for treating acute gastroenteritis are few, and only a few products have the defects of unsatisfactory treatment effect, high cost, complex preparation process, excessive medicinal ingredients and complex components. For example, chinese patent CN109771488A discloses a Chinese patent medicine for treating acute gastroenteritis in children and its preparation process. The Chinese patent medicine for treating infantile acute gastroenteritis is mainly prepared from the following Chinese medicinal materials in parts by mass: 500 portions of astragalus root, 400 portions of engelhardtia chrysolepis, 700 portions of rhizoma coptidis, 50-120 portions of rhizoma coptidis, 500 portions of chuanling, 500 portions of rhizoma cimicifugae, 200 portions of loquat, 350 portions of perilla, and 50-120 portions of perilla. The Chinese patent medicine for treating the acute gastroenteritis of children has reasonable formula, less and refined medicinal ingredients, and can generate good effect of the acute gastroenteritis of children by virtue of synergistic effect of the medicines, however, the Chinese patent medicine is suitable for children, and has the advantage of further improving the treatment effect of the acute gastroenteritis of adults.
Therefore, the Chinese patent medicine preparation for treating acute gastroenteritis, which has the advantages of obvious treatment effect on acute gastroenteritis, no toxic or side effect, less and refined prescription medicine taste, safe use and convenient taking, is in line with market demands, has wide market value and application prospect, and has very important significance for promoting the further development of Chinese patent medicines and relieving the pain of patients with acute gastroenteritis.
Disclosure of Invention
The invention mainly aims to provide a Chinese patent medicine preparation for treating acute gastroenteritis, which has the advantages of obvious treatment effect on acute gastroenteritis, no toxic or side effect, less and refined prescription medicine taste, safe use and convenient taking. Meanwhile, the invention also provides a preparation method of the Chinese patent medicine preparation for treating acute gastroenteritis.
In order to achieve the above purposes, the technical scheme adopted by the invention is as follows: a Chinese patent medicine preparation for treating acute gastroenteritis is characterized by being prepared from the following components: semen litchi, radix aucklandiae, fructus Schisandrae chinensis, flos Sophorae Immaturus, Ginseng radix, rhizoma Dioscoreae and cortex Cinnamomi.
Further, the weight parts of the components are as follows: 8-12 parts of lychee seed, 5-8 parts of elecampane, 2-5 parts of schisandra chinensis, 1-3 parts of sophora flower, 3-6 parts of ginseng, 4-6 parts of Chinese yam and 2-4 parts of cinnamon.
As a preferred embodiment of the invention, the Chinese patent medicine preparation for treating acute gastroenteritis is prepared from the following components in parts by mass: 11.9 parts of lychee seed, 7 parts of costustoot, 3.5 parts of Chinese magnoliavine fruit, 2 parts of sophora flower, 4.5 parts of ginseng, 5 parts of Chinese yam and 3 parts of cinnamon.
As a preferred embodiment of the present invention, the Chinese patent medicine preparation for treating acute gastroenteritis further comprises: 2-4 parts of dried orange peel, 3-5 parts of magnolia officinalis, 2-5 parts of pomegranate rind, 1-3 parts of osbeckia chinensis and 2-5 parts of green tangerine peel.
Another object of the present invention is to provide a method for preparing the Chinese patent medicine preparation for treating acute gastroenteritis, which is characterized by comprising the following steps: grinding the above materials respectively, sieving, mixing, and making into preparation by conventional method.
According to the preparation method of the Chinese patent medicine preparation for treating acute gastroenteritis, the sieving is preferably 500-800 mesh sieving.
According to the preparation method of the Chinese patent medicine preparation for treating acute gastroenteritis, the preparation is preferably at least one of tablets, capsules and water aqua.
According to the preparation method of the Chinese patent medicine preparation for treating acute gastroenteritis in the embodiment of the invention, the grinding machine used for grinding is preferably an ultrafine grinding machine.
The invention also aims to provide a method for taking the Chinese patent medicine preparation for treating acute gastroenteritis, which is taken by warm water, 3 times a day and 5-10g of the Chinese patent medicine preparation for treating acute gastroenteritis once.
The invention also aims to provide application of the Chinese patent medicine preparation for treating acute gastroenteritis in treating acute gastroenteritis.
Due to the application of the technical scheme, compared with the prior art, the invention has the following advantages:
(1) the preparation method of the Chinese patent medicine preparation for treating acute gastroenteritis, provided by the invention, has the advantages that the components are ground and uniformly mixed to prepare the required preparation type, the preparation process is simple, the operation is convenient, the labor intensity is low, the requirements on production equipment and a production line are not high, the preparation method can be directly applied without modifying the original production line, and the safe, efficient and rapid preparation of the medicine can be realized.
(2) The Chinese patent medicine preparation for treating acute gastroenteritis provided by the invention is prepared from the following components: semen litchi, radix aucklandiae, fructus Schisandrae chinensis, flos Sophorae Immaturus, Ginseng radix, rhizoma Dioscoreae and cortex Cinnamomi. Through the mutual matching and the combined action of the components, the composition formed by the components has good treatment effect on acute gastroenteritis, no toxic or side effect and good taste, can supplement nutrition for human body, and can realize the effect of obviously improving or even healing under the condition of small dosage.
(3) The Chinese patent medicine preparation for treating acute gastroenteritis, provided by the invention, comprises the following components in parts by weight: 8-12 parts of lychee seed, 5-8 parts of elecampane, 2-5 parts of schisandra chinensis, 1-3 parts of sophora flower, 3-6 parts of ginseng, 4-6 parts of Chinese yam and 2-4 parts of cinnamon. The components can play their roles and influence each other by adjusting the proportion of the components, so that the prepared preparation has good quality stability, long shelf life, palatable medicinal taste, good compliance for patients, sufficient nutrition and health-care function while treating acute gastroenteritis.
(4) The Chinese patent medicine preparation for treating acute gastroenteritis provided by the invention also comprises the following components: 2-4 parts of dried orange peel, 3-5 parts of magnolia officinalis, 2-5 parts of pomegranate rind, 1-3 parts of osbeckia chinensis and 2-5 parts of green tangerine peel. The prior art does not have the technical inspiration of combining and adding the components into the composition in the technical scheme of the invention, and the components are matched with other components to act together after being added, so that the composition has better treatment effect, lower side effect, better taste, richer nutrition, higher preparation and use safety, exact treatment effect and high cure rate, and can treat both symptoms and root causes.
Detailed Description
The following description is presented to disclose the invention so as to enable any person skilled in the art to practice the invention. The preferred embodiments in the following description are given by way of example only, and other obvious variations will occur to those skilled in the art.
Example 1
A Chinese patent medicine preparation for treating acute gastroenteritis is characterized by being prepared from the following components: semen litchi, radix aucklandiae, fructus Schisandrae chinensis, flos Sophorae Immaturus, Ginseng radix, rhizoma Dioscoreae and cortex Cinnamomi.
The weight parts of the components are as follows: 8 parts of lychee seed, 5 parts of costustoot, 2 parts of Chinese magnoliavine fruit, 1 part of sophora flower, 3 parts of ginseng, 4 parts of Chinese yam and 2 parts of cinnamon.
The Chinese patent medicine preparation for treating acute gastroenteritis further comprises: 2 parts of dried orange peel, 3 parts of magnolia officinalis, 2 parts of pomegranate peel, 1 part of osbeckia chinensis and 2 parts of green tangerine peel.
The preparation method of the Chinese patent medicine preparation for treating acute gastroenteritis is characterized by comprising the following steps of: grinding the above materials respectively, sieving, mixing, and making into preparation by conventional method; the sieving is to sieve by a 500-mesh sieve; the preparation is a tablet; the pulverizer used for pulverizing is a superfine pulverizer.
An application of the Chinese patent medicine preparation for treating acute gastroenteritis in treating acute gastroenteritis is provided.
Example 2
A Chinese patent medicine preparation for treating acute gastroenteritis is characterized by being prepared from the following components: semen litchi, radix aucklandiae, fructus Schisandrae chinensis, flos Sophorae Immaturus, Ginseng radix, rhizoma Dioscoreae and cortex Cinnamomi.
The weight parts of the components are as follows: 9 parts of lychee seed, 6 parts of costustoot, 3 parts of Chinese magnoliavine fruit, 1.5 parts of sophora flower, 4 parts of ginseng, 4.5 parts of Chinese yam and 2.5 parts of cinnamon.
The Chinese patent medicine preparation for treating acute gastroenteritis further comprises: 2.5 parts of dried orange peel, 3.5 parts of officinal magnolia bark, 3 parts of pomegranate bark, 1.5 parts of osbeckia chinensis and 3 parts of green tangerine peel.
The preparation method of the Chinese patent medicine preparation for treating acute gastroenteritis is characterized by comprising the following steps of: grinding the above materials respectively, sieving, mixing, and making into preparation by conventional method; the sieving is 600 mesh sieving; the preparation is a capsule; the pulverizer used for pulverizing is a superfine pulverizer.
An application of the Chinese patent medicine preparation for treating acute gastroenteritis in treating acute gastroenteritis is provided.
Example 3
A Chinese patent medicine preparation for treating acute gastroenteritis is characterized by being prepared from the following components: semen litchi, radix aucklandiae, fructus Schisandrae chinensis, flos Sophorae Immaturus, Ginseng radix, rhizoma Dioscoreae and cortex Cinnamomi.
The weight parts of the components are as follows: 11.9 parts of lychee seed, 7 parts of costustoot, 3.5 parts of Chinese magnoliavine fruit, 2 parts of sophora flower, 4.5 parts of ginseng, 5 parts of Chinese yam and 3 parts of cinnamon.
The Chinese patent medicine preparation for treating acute gastroenteritis further comprises: 3 parts of dried orange peel, 4 parts of officinal magnolia bark, 3.5 parts of pomegranate bark, 2 parts of osbeckia chinensis and 3.5 parts of green tangerine peel.
The preparation method of the Chinese patent medicine preparation for treating acute gastroenteritis is characterized by comprising the following steps of: grinding the above materials respectively, sieving, mixing, and making into preparation by conventional method; the sieving is 650 mesh sieving; the preparation is a water agent; the pulverizer used for pulverizing is a superfine pulverizer.
An application of the Chinese patent medicine preparation for treating acute gastroenteritis in treating acute gastroenteritis is provided.
Example 4
A Chinese patent medicine preparation for treating acute gastroenteritis is characterized by being prepared from the following components: semen litchi, radix aucklandiae, fructus Schisandrae chinensis, flos Sophorae Immaturus, Ginseng radix, rhizoma Dioscoreae and cortex Cinnamomi.
The weight parts of the components are as follows: 11 parts of lychee seed, 7 parts of costustoot, 3.5 parts of Chinese magnoliavine fruit, 2 parts of sophora flower, 4.5 parts of ginseng, 5 parts of Chinese yam and 3 parts of cinnamon.
The Chinese patent medicine preparation for treating acute gastroenteritis further comprises: 3.5 parts of dried orange peel, 4.5 parts of officinal magnolia bark, 4.5 parts of pomegranate bark, 3 parts of osbeckia chinensis and 4.5 parts of green tangerine peel.
The preparation method of the Chinese patent medicine preparation for treating acute gastroenteritis is characterized by comprising the following steps of: grinding the above materials respectively, sieving, mixing, and making into preparation by conventional method; the sieving is 800 mesh sieving; the preparation is a capsule; the pulverizer used for pulverizing is a superfine pulverizer.
An application of the Chinese patent medicine preparation for treating acute gastroenteritis in treating acute gastroenteritis is provided.
Example 5
A Chinese patent medicine preparation for treating acute gastroenteritis is characterized by being prepared from the following components: semen litchi, radix aucklandiae, fructus Schisandrae chinensis, flos Sophorae Immaturus, Ginseng radix, rhizoma Dioscoreae and cortex Cinnamomi.
The weight parts of the components are as follows: 12 parts of lychee seed, 8 parts of costustoot, 5 parts of Chinese magnoliavine fruit, 3 parts of sophora flower, 6 parts of ginseng, 6 parts of Chinese yam and 4 parts of cinnamon.
The Chinese patent medicine preparation for treating acute gastroenteritis further comprises: 4 parts of dried orange peel, 5 parts of officinal magnolia bark, 5 parts of pomegranate bark, 3 parts of osbeckia chinensis and 5 parts of green tangerine peel.
The preparation method of the Chinese patent medicine preparation for treating acute gastroenteritis is characterized by comprising the following steps of: grinding the above materials respectively, sieving, mixing, and making into preparation by conventional method; the sieving is 800 mesh sieving; the preparation is a tablet; the pulverizer used for pulverizing is a superfine pulverizer.
An application of the Chinese patent medicine preparation for treating acute gastroenteritis in treating acute gastroenteritis is provided.
Comparative example 1
The present example provides a Chinese patent medicine preparation for treating acute gastroenteritis, the formulation and preparation method are basically the same as example 1, except that lychee seed is not added.
Comparative example 2
This example provides a Chinese medicinal preparation for treating acute gastroenteritis, which has a formulation and a preparation method substantially the same as those of example 1, except that no radix aucklandiae is added.
In order to further illustrate the beneficial technical effects of the Chinese patent medicine preparation for treating acute gastroenteritis in the embodiment of the present invention, the Chinese patent medicine preparation for treating acute gastroenteritis prepared in the above embodiments 1-5 and comparative examples 1-2 was subjected to clinical experiments, the experimental results are shown in table 1, and the experimental methods are as follows: randomly taking 140 acute gastroenteritis volunteers, randomly dividing into 7 groups, each group corresponding to examples 1-5 and comparative examples 1-2, and orally administering the Chinese medicinal preparation for treating acute gastroenteritis with warm water 3 times a day, 5g each time; statistical patient profiles were observed after 1 week.
The evaluation criteria were:
and (3) curing: the abdominal pain, diarrhea and nausea symptoms disappear completely, and the body returns to normal after being checked.
Improvement: the abdominal pain, diarrhea and nausea symptoms basically disappear, and the physical indexes basically return to normal after being checked;
and (4) invalidation: the symptoms are not improved after the treatment.
TABLE 1 results of clinical experiments
| Item | Cure of disease | Improvement of life | Invalidation | High efficiency |
| Unit of | Human being | Human being | Human being | % |
| Example 1 | 16 | 3 | 1 | 95.0 |
| Example 2 | 18 | 1 | 1 | 95.0 |
| Example 3 | 16 | 4 | 0 | 100.0 |
| Example 4 | 19 | 1 | 0 | 100.0 |
| Example 5 | 20 | 0 | 0 | 100.0 |
| Comparative example 1 | 8 | 6 | 6 | 70.0 |
| Comparative example 2 | 10 | 3 | 7 | 65.0 |
The results of the data show that the effective rate of the Chinese patent medicine preparation for treating acute gastroenteritis is more than or equal to 95.0 percent, and the effective rate of the comparative product is less than or equal to 70.0 percent, so the Chinese patent medicine preparation for treating acute gastroenteritis has better treatment effect and is the result of synergistic effect of all the components.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are merely illustrative of the principles of the invention, but that various changes and modifications may be made without departing from the spirit and scope of the invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (9)
1. A Chinese patent medicine preparation for treating acute gastroenteritis is characterized by being prepared from the following components: semen litchi, radix aucklandiae, fructus Schisandrae chinensis, flos Sophorae Immaturus, Ginseng radix, rhizoma Dioscoreae and cortex Cinnamomi.
2. The Chinese patent medicine preparation for treating acute gastroenteritis according to claim 1, wherein the weight parts of the components are as follows: 8-12 parts of lychee seed, 5-8 parts of elecampane, 2-5 parts of schisandra chinensis, 1-3 parts of sophora flower, 3-6 parts of ginseng, 4-6 parts of Chinese yam and 2-4 parts of cinnamon.
3. The Chinese patent medicine preparation for treating acute gastroenteritis according to claim 1, which is prepared from the following components in parts by mass: 11.9 parts of lychee seed, 7 parts of costustoot, 3.5 parts of Chinese magnoliavine fruit, 2 parts of sophora flower, 4.5 parts of ginseng, 5 parts of Chinese yam and 3 parts of cinnamon.
4. The Chinese patent medicine preparation for treating acute gastroenteritis according to claim 1, further comprising: 2-4 parts of dried orange peel, 3-5 parts of magnolia officinalis, 2-5 parts of pomegranate rind, 1-3 parts of osbeckia chinensis and 2-5 parts of green tangerine peel.
5. A method for preparing a Chinese patent medicinal preparation for treating acute gastroenteritis according to any one of claims 1 to 4, comprising the steps of: grinding the above materials respectively, sieving, mixing, and making into preparation by conventional method.
6. The method for preparing a Chinese patent medicine preparation for treating acute gastroenteritis according to claim 5, wherein the sieving is 500-800 mesh sieving.
7. The preparation method of the Chinese patent medicine preparation for treating acute gastroenteritis according to claim 5, wherein the preparation is at least one of tablets, capsules and water aqua.
8. The method for preparing a Chinese patent drug preparation for treating acute gastroenteritis according to claim 5, wherein the milling machine used for milling is an ultra-fine milling machine.
9. Use of a Chinese medicinal preparation according to any one of claims 1 to 4 for the treatment of acute gastroenteritis.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202111419086.8A CN113925922A (en) | 2021-11-26 | 2021-11-26 | Chinese patent medicine preparation for treating acute gastroenteritis |
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| CN1490021A (en) * | 2002-10-20 | 2004-04-21 | 张满栋 | Chinese patent drug for preventing enterogastrocele |
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| 刘珍华等: "山药五味子粉治疗婴幼儿腹泻26例", 《时珍国医国药》 * |
| 钟晓凤: "泄泻的辨证施护", 《辽宁中医杂志》 * |
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Application publication date: 20220114 |