CN107875281A - A kind of diabetes food drug composition and preparation method thereof - Google Patents

A kind of diabetes food drug composition and preparation method thereof Download PDF

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Publication number
CN107875281A
CN107875281A CN201711239228.6A CN201711239228A CN107875281A CN 107875281 A CN107875281 A CN 107875281A CN 201711239228 A CN201711239228 A CN 201711239228A CN 107875281 A CN107875281 A CN 107875281A
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diabetes
food
drug composition
raw material
food drug
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子荣安
子颖晔
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Yunnan Wildlife Research Institute Of Wild Fungi (limited Partnership)
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Yunnan Wildlife Research Institute Of Wild Fungi (limited Partnership)
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    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
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    • A61K36/8968Ophiopogon (Lilyturf)
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    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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Abstract

The present invention discloses a kind of diabetes food drug composition and preparation method thereof, belongs to health care food medicine technical field.The raw material of the food drug composition eats medicine weight percent composition:The Radix Astragali 12 13%, the dried rhizome of rehmannia 13 14%, the root of kudzu vine 10 11%, radix scrophulariae 10 11%, Chinese yam 8 9%, Poria cocos 7 8%, hawthorn 13 14%, the tuber of dwarf lilyturf 12 13%, Fructus Corni 10 11%.Dry raw medicinal material is taken, cleaning, cleans, after drying, is ground into raw material medicinal powder, then weighs raw material medicinal powder respectively by weight percentage and is well mixed.Have the advantages that therapeutic effect is good, pure natural, inexpensive, convenient to take, the treatment of suitable type II diabetes uses.

Description

A kind of diabetes food drug composition and preparation method thereof
Technical field
The present invention relates to a kind of diabetes food drug composition and preparation method thereof, belongs to health care food medicine technical field.
Background technology
Diabetes are a kind of common endocrine metabolism diseases, and hyperglycaemia is due to then defect of insulin secretion or symbiosis Thing effect is impaired, or both have concurrently and cause, be the disease of the third-largest serious threat human health after tumour, vascular lesion, With high mortality, the feature of high disability rate and high health care costs, turn into asking for the publilc health that whole world various countries face jointly Topic.Diabetes mellitus in China illness rate is up to 9.7%, far above the average illness rate 6.4% in the whole world.Counted within 2016 according to the World Health Organization As shown by data, for China's diabetes number of patients more than 1.1 hundred million, diabetes number of patients accounts for the 1/3 of global diabetes number, Expect the year two thousand forty China diabetic and be up to 1.5 hundred million.
Diabetes have two kinds of I type and II type.IDDM is that one kind causes insulin exhausted due to islet p-cell destruction To lacking, there are the diabetes of Ketosis-prone.Type II diabetes is mainly due to islet beta cell function obstacle and insulin resistance Caused by, and with the development of the course of disease, the damage of islet beta cell function is usually associated with until apoptosis.At present, for I The treatment means of patients with type Ⅰ DM are mainly insulin therapy, and the clinical treatment means of type II diabetes are mainly using oral drop Sugared medicine.
Treatment for type II diabetes, the oral hypoglycemic drug of clinic is currently used for mainly by promoting internal pancreas islet Element secretion increases endogenous GLP-1's to increase the sensitiveness of insulin, or by suppressing dipeptidyl peptidase (DPP-IV) Level, so as to realize the purpose for reducing blood glucose, but its shortcoming is that can only to suppress blood sugar level too high, and β cells can not be prevented to wither Die, " can only cure the symptoms, not the disease ", can not the fundamentally reverting diabetes course of disease development, offer limited effectiveness.Moreover, these medicines are more For chemical drugs, side effect is larger, unsuitable long-term use of.It is, therefore, desirable to provide the treatment primarily directed to patients with NIDDM Prescription, type II diabetes is effectively treated.
The content of the invention
The technical problem to be solved in the present invention is can not fundamentally to reverse sugar for existing type II diabetes medicine The deficiency of disease disease is urinated, a kind of plant composition for treating diabetes and preparation method thereof is proposed, realizes to II type glycosuria Effective treatment of disease.
In order to solve the above technical problems, the present invention provides a kind of diabetes food drug composition, its raw material food medicine weight percent It is than component:Radix Astragali 12-13%, dried rhizome of rehmannia 13-14%, root of kudzu vine 10-11%, radix scrophulariae 10-11%, Chinese yam 8-9%, Poria cocos 7-8%, hawthorn 13-14%, tuber of dwarf lilyturf 12-13%, Fructus Corni 10-11%.Each raw material food medicine is the food medicinal material after drying, dehydration:
The preparation method of diabetes of the present invention food drug composition is:Take respectively the dry Radix Astragali, the dried rhizome of rehmannia, the root of kudzu vine, radix scrophulariae, Chinese yam, Poria cocos, hawthorn, the tuber of dwarf lilyturf, Fructus Corni raw material food medicinal material, go the removal of impurity and mildew and rot rotten part, dry or dry naturally after cleaning It is dry, raw material food medicinal powder is respectively crushed into, then weigh above-mentioned raw materials food medicinal powder respectively by weight percentage, it is well mixed, i.e., Obtain diabetes food drug composition.
The granularity of the raw material food medicinal powder is below 0.5mm, convenient directly edible, absorption.
Diabetes food drug composition product of the present invention is fine-powdered, can directly be taken with warm water, can also fill capsule for medicine side Housecoat is used.
In diabetes food drug composition of the present invention, the percentage by weight of each component bulk drug can be specific true according to being actually needed It is fixed, ensure the effect of good.I.e. according to the sick hair-like condition of diabetes patient, the time length of diabetes, fasting blood-glucose are suffered from Height and the index of correlation relevant with blood glucose rise analysis, depending on the different situations of diabetic, adjust each raw material food The dosage ratio of medicine, to reach optimum efficiency, reach the requirement cured completely.
The raw material food medicine that the present invention uses is respectively provided with the medicinal efficacy for diabetes.
The Radix Astragali:It is sweet warm-natured.Containing astragaloside, astragalus polyose, flavone compound, also containing amino acid, protein, core The Multiple components such as flavine, folic acid, vitamin D, cupreol, daucosterol, caffeic acid, chlorogenic acid, trace element, there is QI invigorating Gu table, arrest sweating admittedly take off, inducing diuresis to remove edema, torr sore apocenosis, regulation blood pressure, regulation blood glucose, liver protecting, strengthen immunity, cardiac stimulant etc. Effect.
The dried rhizome of rehmannia:It is sweet cold in nature.Containing compositions such as rehmannioside, Dihuang polysaccharide, amino acid, there is clearing heat and cooling blood, yin-nourishing, promote the production of body fluid Effect.
The root of kudzu vine:It is sweet cool in nature.Containing the mineral matters such as flavone compound, protein, amino acid, sugar, iron, calcium, copper, selenium, tool There is expelling pathogenic factors from muscles and skin to bring down a fever, promoting eruption, promote the production of body fluid to quench thirst, the effect of Shengyang Zhixie.
Radix scrophulariae:Bitter and puckery flavor is mild-natured.Containing iridoids, phytosterol, oleic acid, leukotrienes, carbohydrate, left-handed asparagine and Alkaloid.With clearing heat and cooling blood, removing toxic substances, dissipating bind relieving sore-throat, the effect of enriching yin.
Chinese yam:It is sweet warm-natured.Containing compositions such as diosgenin, hydrochloric acid Chinese yam alkali, polyphenol oxidase, glycoprotein, have and mend Spleen nourishing the stomach, engender liquid and benefic lung, the puckery smart effect of kidney tonifying.
Poria cocos:It is sweet mild-natured.Containing compositions such as protein, fat, vitamin A, vitamin B, trace elements, disappear with Li Shui Swollen, invigorating the spleen to arrest diarrhea, the effect of mental-tranquilization.
Hawthorn:Sour sweet slightly warm in nature.Containing multivitamin, crataegolic acid, tartaric acid, citric acid, malic acid, flavonoids, sugar The mineral matter such as class, protein, fat and calcium, phosphorus, iron.Have the function that to eat stomach invigorating, promoting blood circulation and removing blood stasis, convergence and dysentery clearly.
The tuber of dwarf lilyturf:Bitter and puckery flavor is mild-natured.Glycosides containing dwarf lilyturf, steroid saponin, alkaloid, sitosterol, glucose, amino acid, Vitamin etc., there is antifatigue, increase hepatic glycogen, improve cellular immune function and hypoglycemic.
Fructus Corni:Sour-puckery flavor slightly warm in nature.Containing volatile ingredient, glucoside and glucoside member, palmitic acid, oleic acid, linoleic acid etc. into Point, have the function that to tonify the liver and kidney, restrain astringent or styptic treatment for spontaneous sweating, astringent sperm contracting urine, hidroschesis, promote the production of body fluid to quench thirst.
The present invention is mixed through scientific compatibility using pure plant food medicinal material, after long-term use of, can effectively be adjusted people The glycometabolism of body, sugar tolerance is improved, promote insulin cell reparation, regeneration and recover function, strengthen immune function of human body, reduce Blood viscosity, prevent cardiovascular and cerebrovascular from surprisingly occurring, and then reduce the purpose of blood glucose.It is good, pure natural, low with therapeutic effect Cost, it is convenient to take the advantages that, the treatment of suitable type II diabetes uses.
Embodiment
The embodiment of the present invention is further described in detail below.Unreceipted technology or production in embodiment Product are prior art or can be by buying the conventional products obtained.
Embodiment 1:The raw material of diabetes food drug composition eats medicine weight percent composition and is:The Radix Astragali 12.6%(252g), it is raw Ground 13.44%(268.8g), the root of kudzu vine 10.92%(218.4g), radix scrophulariae 10.92%(218.4g), Chinese yam 8.4%(168g), Poria cocos 7.56%(151.2g), hawthorn 13.44%(268.8g), the tuber of dwarf lilyturf 12.64%(252.8g), Fructus Corni 10.08%(201.6g);Each original Material food medicine is the food medicinal material after drying, dehydration.
The preparation method of thing is:The dry Radix Astragali, the dried rhizome of rehmannia, the root of kudzu vine, radix scrophulariae, Chinese yam, Poria cocos, hawthorn, the tuber of dwarf lilyturf, mountain are taken respectively Fruit of medicinal cornel raw medicinal material, the removal of impurity and mildew and rot rotten part are gone, dries or dries naturally after cleaning, be respectively crushed into Below 0.5mm raw material food medicinal powder, then weigh above-mentioned raw materials food medicinal powder respectively by weight percentage, it is well mixed, that is, obtains sugar Urine disease food drug composition.
The diabetes food drug composition of the present embodiment is used to treat certain patients with NIDDM(52 years old), with 1 month for one The individual course for the treatment of.The patient suffers from diabetes 3 years, fasting blood-glucose 13mmol/L, takes melbine always and maintains the substantially flat of blood glucose Surely.This diabetes food drug composition is continuously taken afterwards, it is early, middle and late three times per natural gift, mixed with warm water take 22g every time.Take 10 The former melbine and Acarbose taken is disabled after it, hospital's check fasting blood-glucose is down to 9.3mmol/L after two weeks, after half a year Fasting blood-glucose is down to 7.2mmol/L, and fasting blood-glucose is down to 4.7mmol/L after 1 year, reaches the purpose cured completely.Hereafter adjust Taken twice for early, evening, after treatment half a year, blood glucose is normal, and diet and body have recovered normal, have no bounce-back.
Embodiment 2:The raw material of diabetes food drug composition eats medicine weight percent composition and is:The Radix Astragali 13%(260g), the dried rhizome of rehmannia 13.3%(266g), the root of kudzu vine 10%(200g), radix scrophulariae 11%(220g), Chinese yam 8%(160g), Poria cocos 8%(160g), hawthorn 14% (280g), the tuber of dwarf lilyturf 12%(240g), Fructus Corni 10.7%(214g);Each raw material food medicine is the food medicinal material after drying, dehydration.
The diabetes food drug composition preparation method be:Take respectively the dry Radix Astragali, the dried rhizome of rehmannia, the root of kudzu vine, radix scrophulariae, Chinese yam, Poria cocos, hawthorn, the tuber of dwarf lilyturf, Fructus Corni raw medicinal materials, the removal of impurity and mildew and rot rotten part are gone, dries or dries naturally after cleaning, Below 0.2mm raw material food medicinal powder is respectively crushed into, then weighs above-mentioned raw materials food medicinal powder, mixing respectively by weight percentage Uniformly, that is, diabetes food drug composition is obtained.
The diabetes food drug composition of the present embodiment is used to treat certain diabetic(60 years old), it was a treatment with 1 month Journey.The patient suffered from diabetes before 7 years, during morbidity, clinical manifestation be breathes hard, night night sweat, legs and feet cramp, do not feel like eating, Great quantity of water drinking, diuresis, ten days bodies of falling ill decline 20 kilograms, serious dehydration occur.Through examination in hospital, fasting blood-glucose is up to 33mmol/L, clinical manifestation are diabetic ketoacidosis.After in hospital, treated with insulin injection, maintain glucostasis 3 Year.Hereafter, patient continuously takes this diabetes food drug composition, takes per natural gift are early, middle and late, is mixed every time with warm water three times Take 22g.Stop insulin injection after taking 3 months, 9.5mmol/L is down to through hospital's check fasting blood-glucose;After continue to take this sugar Urine disease food 5 courses for the treatment of of drug composition, 6.3mmol/L is down to through hospital's check fasting blood-glucose, uninterrupted monitoring blood glucose during taking, Dosage is adjusted to early, evening, persistently medication 1 year half, rear fasting blood-glucose was held between 6.0-7.0mmol/L, treatment twice Work well.
Embodiment 3:The raw material of diabetes food drug composition eats medicine weight percent composition and is:The Radix Astragali 12%(240g), the dried rhizome of rehmannia 13.8%(276g), the root of kudzu vine 10.5%(210g), radix scrophulariae 10%(200g), Chinese yam 9%(180g), Poria cocos 7%(140g), hawthorn 13.9% (278g), the tuber of dwarf lilyturf 12.8%(256g), Fructus Corni 11%(220g);Each raw material food medicine is the food medicinal material after drying, dehydration.
The diabetes food drug composition preparation method be:Take respectively the dry Radix Astragali, the dried rhizome of rehmannia, the root of kudzu vine, radix scrophulariae, Chinese yam, Poria cocos, hawthorn, the tuber of dwarf lilyturf, Fructus Corni raw medicinal materials, the removal of impurity and mildew and rot rotten part are gone, dries or dries naturally after cleaning, Below 0.1mm raw material food medicinal powder is respectively crushed into, then weighs above-mentioned raw materials food medicinal powder, mixing respectively by weight percentage Uniformly, that is, diabetes food drug composition is obtained.
The diabetes food drug composition of the present embodiment is used to treat certain patients with NIDDM(57 years old), with 1 month for one The individual course for the treatment of.Before taking this food drug composition, the patient has suffered from diabetes 9 years, and during morbidity, fasting blood-glucose is repeatedly checked through hospital Between 9-13mmol/L, type II diabetes is diagnosed as, takes Chinese medicine expectant treatment ever since, but the state of an illness does not improve, it is empty Abdomen blood glucose is still between 9-12mmol/L.After start to take this diabetes food drug composition, is taken three times per natural gift are early, middle and late, Mixed every time with warm water and take 22g.After taking half a year, fasting blood-glucose is down to 6.2mmol/L, but irregular, frequently due to living Drink, cause blood glucose to rise to 9.8 mmol/L again, 4 treatments of this food drug composition are taken by adjusting life style and holding on Journey, 7.1mmol/L is had dropped to through hospital's check fasting blood-glucose, effectively controls blood glucose.It is adjusted to early afterwards, evening continues twice Take so far, blood glucose keeps stable.
Embodiment 4-8:The raw material food medicine weight percent composition such as following table of each embodiment diabetes food drug composition, each original Material food medicine is the food medicinal material after drying, dehydration:
Diabetes food drug composition is prepared using with previous embodiment identical method in the various embodiments described above, raw material food medicinal material Grinding particle size be below 0.1-0.5mm.
Diabetes food drug composition is used to treat five groups of patients with NIDDM obtained by above-described embodiment(Every group of 5 people), with 1 Individual month is a course for the treatment of, early, middle and late three times per natural gift, each 22g, with warm water mixes clothes.Continuously take this diabetes food medicine group After 1-2 course for the treatment of of compound, fasting blood-glucose is decreased obviously, empty after continuously taking this diabetes food 3-7 course for the treatment of of drug composition Abdomen blood glucose is down to below 7.0mmol/L, and is showed no state of an illness bounce-back.
The technology contents of the present invention are described above, but protection scope of the present invention is not limited to the content, , can also be on the premise of present inventive concept not be departed to this hair in one of ordinary skill in the art's possessed knowledge Bright technology contents make a variety of changes, within the spirit and principles of the invention, any modification for being made, equivalent substitution, Improve etc., it should be included in the scope of the protection.

Claims (3)

1. a kind of diabetes eat drug composition, it is characterised in that:The raw material of the composition eats medicine weight percent composition:It is yellow Stilbene 12-13%, dried rhizome of rehmannia 13-14%, root of kudzu vine 10-11%, radix scrophulariae 10-11%, Chinese yam 8-9%, Poria cocos 7-8%, hawthorn 13-14%, the tuber of dwarf lilyturf 12-13%, Fructus Corni 10-11%.
A kind of 2. preparation method of the diabetes food drug composition described in claim 1, it is characterised in that:Dry Huang is taken respectively Stilbene, the dried rhizome of rehmannia, the root of kudzu vine, radix scrophulariae, Chinese yam, Poria cocos, hawthorn, the tuber of dwarf lilyturf, Fructus Corni raw medicinal material, go the removal of impurity and mildew and rot rotten portion Point, dry or dry naturally after cleaning, be respectively crushed into raw material food medicinal powder, then weigh above-mentioned original respectively by weight percentage Material food medicinal powder, is well mixed, that is, obtains diabetes food drug composition.
3. the preparation method of diabetes food drug composition according to claim 2, it is characterised in that:The raw material eats medicinal powder Granularity be below 0.5mm.
CN201711239228.6A 2017-11-30 2017-11-30 A kind of diabetes food drug composition and preparation method thereof Pending CN107875281A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109528946A (en) * 2019-01-21 2019-03-29 杨景屏 Reduce Chinese medicine composition and its application and particle, tablet and preparation method thereof of blood glucose

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Application publication date: 20180406