CN113750065A - Spleen-tonifying and lung-benefiting pill, preparation method and special processing method of raw materials - Google Patents
Spleen-tonifying and lung-benefiting pill, preparation method and special processing method of raw materials Download PDFInfo
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Abstract
The invention discloses a spleen-tonifying and lung-benefiting pill, a preparation method and a special processing method of raw materials, wherein the spleen-tonifying and lung-benefiting pill consists of the following raw materials: radix Codonopsis, rhizoma Dioscoreae, radix astragali, Poria processed with mare's milk, fructus Amomi, rhizoma Atractylodis processed with oleum Sesami, radix Ophiopogonis, Atractylodis rhizoma, fructus Schisandrae, semen Nelumbinis, fructus Jujubae, and Glycyrrhrizae radix. In the composition of the pill for tonifying spleen and lung, the codonopsis pilosula and the Chinese yam have the effects of tonifying spleen and lung; radix astragali has effects of invigorating qi and benefiting lung. Three of the raw materials specially prepared: the formula comprises Indian buead processed by mare's milk, salted fructus amomi and rhizoma atractylodis fried by sesame oil, and has unique effects of strengthening spleen and tonifying spleen. Other flavors are all effective supplements for the spleen-tonifying and lung-benefiting effects. The spleen-tonifying and lung-benefiting pill has reasonable formula, accords with the principle of monarch, minister, assistant and guide formula of traditional Chinese medicine, and has unique effects of tonifying spleen, invigorating qi and benefiting lung.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a spleen-tonifying and lung-benefiting pill, a preparation method and a special processing method of raw materials.
Background
With the increasing living standard of modern people, the diets of people are diversified. The diet health problem is gradually highlighted, and dysfunction of the spleen and the lung is a common symptom and often troubles people.
The pattern of qi deficiency of both the spleen and lung refers to the condition of weakness due to qi deficiency of both the spleen and lung. The clinical symptoms mainly include cough and asthma, anorexia, abdominal distension and loose stool. Codonopsis pilosula, sweet in flavor and mild in nature; spleen and lung meridian entered; has effects in invigorating spleen, benefiting lung, nourishing blood, and promoting salivation; can be used for treating deficiency of spleen-qi and lung-qi, anorexia, listlessness, cough, asthma, deficiency of qi and blood, sallow complexion, palpitation, short breath, thirst due to body fluid consumption, internal heat, and diabetes. Astragalus root, sweet in taste, slightly warm; entering lung and spleen meridians; has effects in invigorating qi, invigorating yang, consolidating superficial resistance, arresting sweating, inducing diuresis, relieving swelling, promoting salivation, nourishing blood, activating stagnancy, and relieving arthralgia; is suitable for treating deficiency of middle-warmer energy, sweating due to deficiency, short breath, and asthenia. The codonopsis pilosula and astragalus root combined medicine is used as a medicine composition for tonifying spleen and benefiting lung, use records are available in a traditional Chinese medicine prescription, but the traditional Chinese medicine prescription has good control on partial symptoms of a patient, but the treatment effect is not comprehensive, and the effect has a great promotion space.
Disclosure of Invention
Aiming at the problem of dysfunction of the spleen and the lung of people, the invention aims to provide a pill for tonifying the spleen and benefiting the lung, a preparation method and a special processing method of raw materials.
The applicant is a member of the life of the ancestor who is a heritage of non-material culture inherits the traditional Chinese medicine inheritance venation of father ancestors. He found an empirical prescription of [ moistening the spleen and stomach ] from a book of Mr. Huochun Dan House medical record of Mr. Heng, a famous medical doctor of the Qing Dynasty. The spleen-tonifying and lung-benefiting pill is innovatively developed by combining the modern traditional Chinese medicine theory and medication habits through years of research and clinical diagnosis and treatment. The pill for tonifying spleen and benefiting lung is used by Mr. in an outpatient room to treat the dysfunction of spleen and lung, and has good effect.
In order to achieve the above purpose, the invention adopts the technical scheme that:
the spleen-tonifying and lung-benefiting pill is prepared from the following raw materials in parts by weight: 10.0-30.0% of codonopsis pilosula, 10.0-30.0% of Chinese yam, 5.5-15.0% of astragalus membranaceus, 3.5-15.0% of Indian buead processed by mare's milk, 2.0-10.0% of villous amomum fruit, 2.0-10.0% of rhizoma atractylodis processed by sesame oil, 2.5-8.0% of dwarf lilyturf tuber, 4.0-11.0% of largehead atractylodes rhizome, 2.0-7.0% of Chinese magnoliavine fruit, 2.5-8.0% of lotus seed, 2.5-8.0% of Chinese date and 1.2-4.0% of liquorice.
Further, the spleen-tonifying and lung-benefiting pill is prepared from the following raw materials in parts by weight: 18.0-25.0% of codonopsis pilosula, 18.0-25.0% of Chinese yam, 8.5-12.0% of astragalus membranaceus, 6.5-12.0% of Indian buead processed by mare's milk, 3.0-8.0% of villous amomum fruit, 3.0-8.0% of rhizoma atractylodis processed by sesame oil, 3.5-7.0% of dwarf lilyturf tuber, 6.0-9.0% of largehead atractylodes rhizome, 3.0-6.0% of Chinese magnoliavine fruit, 3.5-7.0% of lotus seed, 3.5-7.0% of Chinese date and 2.0-3.0% of liquorice.
In the composition of the pill for tonifying spleen and lung, the codonopsis pilosula and the Chinese yam have the effects of tonifying spleen and lung; radix astragali has effects of invigorating qi and benefiting lung; other flavors are all effective supplements for the spleen-tonifying and lung-benefiting effects. The spleen-tonifying and lung-benefiting pill has reasonable formula, accords with the principle of monarch, minister, assistant and guide formula of traditional Chinese medicine, and has unique effects of tonifying spleen, invigorating qi and benefiting lung. Three of the raw materials specially prepared: the formula comprises Indian buead processed by mare's milk, salted fructus amomi and rhizoma atractylodis fried by sesame oil, and has unique effects of strengthening spleen and tonifying spleen.
The changes of the property, taste and function of the herbs are recorded in Qing De concocting with herbs. That is, the property and taste of the herbs can be changed by processing the herbs, so as to change their functions. Ming Dy Li Ting is loaded in Yi Xue Men, where the herbs are stir-baked with honey for lung, salt for kidney and vinegar for liver. The Ming Dynasty famous medical Li Zhen Zi also says that the Ming Dynasty famous medical Li Zhen Zi is processed with wine to raise the body weight, and then with salt to moisten the body weight and then with vinegar to astringe the body weight. The "guiding the herbs to the meridians" is one of the objectives of processing Chinese herbs, and the special selection of Chinese herbs can be enhanced or changed by processing the Chinese herbs with different excipients.
The preparation method of the three special raw materials comprises the following steps:
the preparation method of the salty fructus amomi comprises the following steps: adding water into fructus amomi, salt and salt, and stirring to prepare 50-100 (g/L) saline water; according to the solid-liquid ratio of fructus amomi to saline water (2.5-5): 1(kg/L), stirring uniformly, standing and soaking for 3-18 h; placing in a frying container, heating with slow fire, taking out when the surface is dry, and cooling.
Further, the preparation method of the fructus amomi salted comprises the following steps: adding water into fructus amomi, salt and salt, and stirring to prepare 60-80 (g/L) saline water; according to the solid-liquid ratio of fructus amomi to saline water (3-4): 1(kg/L), stirring uniformly, standing and soaking for 6-12 h; placing in a frying container, heating with slow fire, taking out when the surface is dry, and cooling.
The preparation method of the rhizoma atractylodis fried with sesame oil comprises the following steps: putting rhizoma Atractylodis in a stir-frying container, and heating with slow fire; taking sesame oil, and mixing the rhizoma atractylodis and the sesame oil according to the solid-to-liquid ratio (7-15): 1(kg/L), spraying oleum Sesami, parching until the surface is glossy, taking out, and cooling.
Further, the preparation method of the rhizoma atractylodis fried with sesame oil comprises the following steps: putting rhizoma Atractylodis in a stir-frying container, and heating with slow fire; taking sesame oil, and mixing the rhizoma atractylodis and the sesame oil according to the solid-to-liquid ratio (9-11): 1(kg/L), spraying oleum Sesami, parching until the surface is glossy, taking out, and cooling.
The preparation method of the Indian buead prepared from the mare's milk comprises the following steps: taking the poria blocks, putting the poria blocks into a frying container, and heating the poria blocks by slow fire; taking horse milk, and mixing the horse milk with poria cocos and the horse milk according to the solid-to-liquid ratio (5-10): 1(kg/L), spraying horse milk while parching, mixing, taking out, and cooling.
Further, the preparation method of the mare milk poria cocos comprises the following steps: taking the poria blocks, putting the poria blocks into a frying container, and heating the poria blocks by slow fire; taking horse milk, and mixing the horse milk with poria cocos and the horse milk according to the solid-to-liquid ratio (6-8): 1(kg/L), spraying horse milk while parching, mixing, taking out, and cooling.
Compared with the prior art, the three special raw materials have the following advantages:
preparing poria cocos from horse milk: poria cocos, sweet and light in flavor, neutral in nature, enters heart, lung, spleen and kidney channels, and has the effects of promoting diuresis, eliminating dampness, invigorating spleen and calming heart. Mare's milk, sweet in taste, cool in nature, has the effects of enriching blood, moistening dryness, clearing heat and quenching thirst. The Indian buead is prepared by the mare's milk, which not only relieves the effects of diuresis and dampness removal of the Indian buead to prevent the Indian buead from excessively inducing diuresis and excreting dampness, but also enhances the spleen-tonifying effect of the Indian buead, and the preparation method of the Indian buead prepared by the mare's milk is unique and achieves two purposes by one.
And (2) fructus amomi salted: fructus amomi is pungent in taste and warm in nature, enters spleen, stomach and kidney channels, and has the effects of resolving dampness, stimulating appetite, warming spleen, checking diarrhea, regulating qi and preventing miscarriage. The preparation method of the fructus amomi enables the fructus amomi to warm the spleen and stop diarrhea and warm the kidney and strengthen yang, and the medicine has double effects.
Roasting rhizoma atractylodis with sesame oil: rhizoma atractylodis, pungent and bitter in flavor and warm in nature, enters spleen, stomach and liver channels, and has the effects of eliminating dampness, strengthening spleen, dispelling wind and cold and improving eyesight. The sesame oil is sweet in taste and cool in nature, and has the effects of relaxing bowel, detoxifying and promoting tissue regeneration. The rhizoma atractylodis is roasted by sesame oil, dampness of the rhizoma atractylodis is discharged out of a body by relaxing bowels by the sesame oil, the dampness excess of the rhizoma atractylodis is relieved by detoxification of the sesame oil, and the effect of the rhizoma atractylodis in strengthening spleen is not influenced by the sesame oil.
According to the invention, the medicinal raw materials are prepared by using special processing methods such as salt fructus amomi, sesame oil roasted rhizoma atractylodis, mare milk prepared poria cocos and the like, so that the performance is improved, and the effects of tonifying spleen and benefiting lung are achieved.
The invention also aims to provide a preparation method of the spleen-tonifying and lung-benefiting pill, which comprises the following steps:
(1) processing raw materials:
weighing the following raw materials in parts by weight: 75-225 g of codonopsis pilosula, 75-225 g of Chinese yam, 40-120 g of astragalus, 40-120 g of poria cocos processed with mare's milk, 15-45 g of fructus amomi preparata, 15-45 g of rhizoma atractylodis fried with sesame oil, 20-60 g of radix ophiopogonis, 30-90 g of bighead atractylodes rhizome, 15-45 g of schisandra chinensis, 20-60 g of lotus seed, 20-60 g of Chinese date and 10-30 g of liquorice. Crushing the raw materials of each component into fine powder by using a crusher respectively, sieving the fine powder by using a sieve of 100-200 meshes, and uniformly mixing the medicinal powder of each component for later use;
(2) processing auxiliary materials-refining honey:
pouring honey into a honey refining pot for refining honey, boiling the honey with strong fire, removing froth impurities, refining with slow fire until the honey is orange yellow;
(3) preparation of the pill:
A. blank preparation: weighing the weight of the mixed medicinal powder, and mixing the medicinal powder and the honey according to the solid-liquid ratio of 1: (1.1-1.5), slowly and discontinuously pouring the honey into the mixed medicinal powder while stirring, and when the dry medicinal powder is basically not seen, continuously mixing and stirring to fully and uniformly mix the honey and the medicinal powder, and pouring the honey into a clean container to knead the honey into blanks;
B. pelleting: cutting the prepared honey base into a plurality of equal parts; twisting each honey blank into a strip shape, wherein the cross section diameter of the twisted medicine strip is 1-2 cm; cutting the medicine strip into a plurality of small pills with the weight of 11 +/-1 g; finally kneading into pills, bagging and packaging. The traditional Chinese medicine pill for tonifying spleen and benefiting lung is obtained.
The invention also aims to provide a finished product dosage form prepared from the traditional Chinese medicine composition for tonifying spleen and benefiting lung, wherein the finished product dosage form comprises pills, tablets, granules, paste or powder.
The oral dosage form of the Chinese medicinal composition of the invention is usually a pill.
The dosage form of the Chinese medicinal composition of the invention is not limited to the pill of the invention, but also includes oral liquid, tablet, capsule, suspension and the like. When different dosage forms are prepared, the traditional Chinese medicine composition also comprises carriers allowed to be used in pharmaceutics, such as excipient and auxiliary material, besides the medicinal ingredients in the traditional Chinese medicine composition.
Detailed Description
The following describes in detail specific embodiments of the present invention. It should be understood that the detailed description and specific examples, while indicating the present invention, are given by way of illustration and explanation only, not limitation.
EXAMPLE 1 preparation of three particular starting materials
A. Preparing the salted fructus amomi:
adding water into fructus Amomi, salt, and stirring to obtain 70g/L salt water; according to the solid-liquid ratio of fructus amomi to saline water of 3.5: 1(kg/L), stirring uniformly, standing and soaking for 8 h; placing in a frying container, heating with slow fire, taking out when the surface is dry, and cooling.
B. Preparing rhizoma atractylodis fried with sesame oil:
putting rhizoma Atractylodis in a stir-frying container, and heating with slow fire; taking sesame oil, and mixing the rhizoma atractylodis and the sesame oil according to the solid-to-liquid ratio of 10: 1(kg/L), spraying oleum Sesami, parching until the surface is glossy, taking out, and cooling.
C. Preparing horse milk poria cocos:
taking the poria blocks, putting the poria blocks into a frying container, and heating the poria blocks by slow fire; taking horse milk, and mixing the raw materials according to the solid-to-liquid ratio of the poria cocos to the horse milk of 6: 1(kg/L), spraying horse milk while parching, mixing, taking out, and cooling.
Example 2 preparation of a powder of a Chinese medicinal composition for invigorating spleen and benefiting lung
Weighing the following raw materials in parts by weight: 150 g of codonopsis pilosula, 150 g of Chinese yam, 80 g of astragalus, 80 g of Indian buead processed with mare's milk, 30 g of villous amomum fruit, 30 g of rhizoma atractylodis fried with sesame oil, 40 g of dwarf lilyturf tuber, 60 g of largehead atractylodes rhizome, 30 g of Chinese magnoliavine fruit, 40 g of lotus seed, 40 g of Chinese date and 20 g of liquoric root, all the components are respectively ground into fine powder by a grinder, and the fine powder is sieved by a 150-mesh sieve and mixed uniformly to obtain the traditional Chinese medicine composition powder for tonifying spleen and lung; packaging into bags, each bag is 25 g, and the total amount is 30 bags.
The medication method comprises the following steps: it is administered with warm water 1 bag each time, 3 times daily.
Example 3 preparation of a spleen-invigorating and lung-benefiting pill
(1) Processing raw materials:
weighing the following raw materials in parts by weight: 150 g of codonopsis pilosula, 150 g of Chinese yam, 80 g of astragalus membranaceus, 80 g of Indian buead processed with mare's milk, 30 g of villous amomum fruit, 30 g of rhizoma atractylodis processed with sesame oil, 40 g of dwarf lilyturf tuber, 60 g of largehead atractylodes rhizome, 30 g of Chinese magnoliavine fruit, 40 g of lotus seed, 40 g of Chinese date and 20 g of liquorice, crushing the raw materials of the components into fine powder by using a crusher respectively, sieving the fine powder by a 150-mesh sieve, and uniformly mixing the medicinal powder of the components for later use;
(2) processing auxiliary materials-refining honey:
pouring honey into a honey refining pot for refining honey, boiling the honey with strong fire, removing froth impurities, refining with slow fire until the honey is orange yellow;
(3) preparation of the pill:
A. blank preparation: weighing the weight of the mixed medicinal powder, and mixing the medicinal powder and the honey according to the solid-liquid ratio of 1: 1.2, slowly and discontinuously pouring the refined honey into the mixed medicinal powder while stirring, continuing to mix and stir when the dry medicinal powder is basically not seen, fully and uniformly mixing the refined honey and the medicinal powder, pouring the mixture into a clean container, and kneading the mixture into a blank;
B. pelleting: cutting the prepared honey base into a plurality of equal parts; twisting each honey blank into strips respectively, wherein the cross section diameter of each twisted medicine strip is 1 cm; cutting the medicine strip into 150 pills with the weight of 11 +/-1 g; finally kneading into pills, obtaining 150 pills in total, and packaging into bags. ,
the medication method comprises the following steps: it is administered with warm water 5 pills each time, 3 times daily.
Test example 1 acute toxicity test
Test materials:
animals: 36 mice are taken, each mouse weighs 18 g-22 g, and the male and female halves are respectively.
Medicine preparation: the invention relates to a pulverized traditional Chinese medicine composition powder.
Mice were randomly divided into 3 groups of 12 mice each, male and female halves. The drug powder was adjusted to a paste (maximum concentration) and each mouse was perfused with a maximum dose of the drug twice a day for 14 consecutive days and observed for the condition of the animals. In the observation period of 14 days, the mice were normal in appetite, activity, hair color, mental status, etc., developed normally, and had no death. The medicine of the present invention has high safety, no obvious side effect and very low acute toxicity.
Test example 2 drug efficacy test
The influence of the traditional Chinese medicine composition on the mouse cough model is as follows:
comparing the whole formula with the formula: the prescription removing group does not contain the Indian buead prepared from mare's milk, the villous amomum fruit and the stir-fried Chinese atractylodes rhizome with sesame oil, and the whole prescription group and the prescription removing group are applied in a stomach-filling mode by using traditional Chinese medicine composition powder.
Mice are randomly divided into model control groups, and a blank control group, a full formula high dose group, a full formula low dose group, a formula-disassembled high dose group and a full formula low dose group are arranged. The administration is carried out by intragastric administration for 3 days every day, and after the last administration for 1h, the mice are placed in a bell jar, and concentrated ammonia water is uniformly sprayed for 5s to stimulate the mice to cause cough, and the cough frequency of the mice within 2min is observed.
TABLE 1 Effect of Chinese medicinal composition on mouse cough model
Note: p < 0.05, P < 0.01 compared to the blank control.
The experimental result shows that compared with a blank control group, the cough times of the high-dose group and the low-dose group of the whole formula have statistical significance, and the cough times of the high-dose group and the low-dose group of the formula are obviously different, which shows that the traditional Chinese medicine components mainly comprising codonopsis pilosula, astragalus and the like have an inhibiting effect on the cough caused by strong ammonia water, but the formula of the Chinese medicine composition has a more obvious inhibiting effect on the cough caused by strong ammonia water, and the effect after the formula is removed is lower than that of the formula of the whole formula.
Test example 3 clinical test
General materials: 99 adult patients with spleen-lung qi deficiency diagnosed by traditional Chinese medicine in last two years are selected as study objects, 42 young people of 18-29 years old are selected, 22 male people and 20 female people are selected, 57 middle-aged people of 30-60 years old are selected, and 28 male people and 28 female people simultaneously meet the requirements of low immune function, repeated respiratory tract infection and western medicine diagnosis.
Dividing the tested population into powder group, pill group and control group according to a random control grouping method, wherein each group comprises 33 patients, and the sex and age of each patient are uniformly distributed. The common data of the three groups of patients, such as the disease causes, the past history, the family environment and the like, are compared, have no significant difference (P is more than 0.05), and have comparability. The clinical efficacy changes of the powder group, the pill group and the control group after treatment are shown in table 1.
Clinical symptom assessment criteria:
and (3) healing: clinical symptoms and physical signs disappear or basically disappear, and the syndrome score is reduced by more than or equal to 95 percent; remarkably: the clinical symptoms and physical signs are obviously improved, and the syndrome integral is reduced by more than or equal to 70 percent; the method has the following advantages: the clinical symptoms and physical signs are all improved, the syndrome integral is reduced by more than or equal to 30 percent, and the effect is not good: clinical symptoms and physical signs are not obviously improved or even aggravated, and the syndrome integral is reduced by less than 30%.
TABLE 2 clinical efficacy changes after treatment of powder group, pill group and control group
As can be seen from the above table, the syndrome score of the treatment group (powder group and pill group) is reduced by 12 points before and after treatment (12.56 points for powder group and 12.16 points for pill group), which is significantly higher than 8.34 points for the control group, and the treatment efficacy of the treatment group reaches 96.97%, and is also significantly better than 84.85% of the control group. The traditional Chinese medicine composition has obvious effect on the treatment effect of tonifying spleen and benefiting lung.
According to the invention, the medicinal materials are processed by using special methods such as salt fructus amomi, sesame oil roasted rhizoma atractylodis, mare milk prepared poria cocos and the like, so that the performance of the medicinal materials is improved, and the effects of tonifying spleen and benefiting lung are achieved.
According to the traditional Chinese medicine composition, the codonopsis pilosula and the Chinese yam have the effects of tonifying spleen and benefiting lung; astragalus root, radix astragali, etc. has the effects of invigorating qi and benefiting lung. Other flavors are all effective supplements for the spleen-tonifying and lung-benefiting effects. The formula is reasonable, accords with the principle of monarch, minister, assistant and guide formula of traditional Chinese medicine, and has the unique effects of tonifying spleen, tonifying qi and benefiting lung. The three specially prepared raw materials, namely the Indian buead prepared from mare's milk, the villous amomum fruit salt and the rhizoma atractylodis fried with sesame oil, have unique effects of strengthening spleen and tonifying spleen in the formula.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are merely illustrative of the principles of the invention, but that various changes and modifications may be made without departing from the spirit and scope of the invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (10)
1. The spleen-tonifying and lung-benefiting pill is characterized by comprising the following raw materials in parts by weight: 10.0-30.0% of codonopsis pilosula, 10.0-30.0% of Chinese yam, 5.5-15.0% of astragalus membranaceus, 3.5-15.0% of Indian buead processed by mare's milk, 2.0-10.0% of villous amomum fruit, 2.0-10.0% of rhizoma atractylodis processed by sesame oil, 2.5-8.0% of dwarf lilyturf tuber, 4.0-11.0% of largehead atractylodes rhizome, 2.0-7.0% of Chinese magnoliavine fruit, 2.5-8.0% of lotus seed, 2.5-8.0% of Chinese date and 1.2-4.0% of liquorice.
2. The pill for tonifying spleen and lung according to claim 1, wherein the Chinese medicinal composition comprises the following raw materials by weight: 18.0-25.0% of codonopsis pilosula, 18.0-25.0% of Chinese yam, 8.5-12.0% of astragalus membranaceus, 6.5-12.0% of Indian buead processed by mare's milk, 3.0-8.0% of villous amomum fruit, 3.0-8.0% of rhizoma atractylodis processed by sesame oil, 3.5-7.0% of dwarf lilyturf tuber, 6.0-9.0% of largehead atractylodes rhizome, 3.0-6.0% of Chinese magnoliavine fruit, 3.5-7.0% of lotus seed, 3.5-7.0% of Chinese date and 2.0-3.0% of liquorice.
3. The processing method of raw materials of the spleen-tonifying and lung-benefiting pill as claimed in claim 1, wherein the preparation method of the salted fructus amomi is as follows: adding water into fructus amomi, salt and salt, and stirring to prepare 50-100 (g/L) saline water; according to the solid-liquid ratio of fructus amomi to saline water (2.5-5): 1(kg/L), stirring uniformly, standing and soaking for 3-18 h; placing in a frying container, heating with slow fire, taking out when the surface is dry, and cooling.
4. The processing method of raw materials of the spleen-tonifying and lung-benefiting pill as claimed in claim 3, wherein the preparation method of the salted fructus amomi is as follows: adding water into fructus amomi, salt and salt, and stirring to prepare 60-80 (g/L) saline water; according to the solid-liquid ratio of fructus amomi to saline water (3-4): 1(kg/L), stirring uniformly, standing and soaking for 6-12 h; placing in a frying container, heating with slow fire, taking out when the surface is dry, and cooling.
5. The raw material processing method of the spleen-tonifying and lung-benefiting pill as claimed in claim 1, wherein the preparation method of the rhizoma atractylodis fried with sesame oil is as follows: putting rhizoma Atractylodis in a stir-frying container, and heating with slow fire; taking sesame oil, and mixing the rhizoma atractylodis and the sesame oil according to the solid-to-liquid ratio (7-15): 1(kg/L), spraying oleum Sesami, parching until the surface is glossy, taking out, and cooling.
6. The raw material processing method of the spleen-tonifying and lung-benefiting pill as claimed in claim 5, wherein the preparation method of the rhizoma atractylodis fried with sesame oil is as follows: putting rhizoma Atractylodis in a stir-frying container, and heating with slow fire; taking sesame oil, and mixing the rhizoma atractylodis and the sesame oil according to the solid-to-liquid ratio (9-11): 1(kg/L), spraying oleum Sesami, parching until the surface is glossy, taking out, and cooling.
7. The processing method of raw materials of the spleen-tonifying and lung-benefiting pill as claimed in claim 1, wherein the preparation method of the mare's milk poria cocos is as follows: taking the poria blocks, putting the poria blocks into a frying container, and heating the poria blocks by slow fire; taking horse milk, and mixing the horse milk with poria cocos and the horse milk according to the solid-to-liquid ratio (5-10): 1(kg/L), spraying horse milk while parching, mixing, taking out, and cooling.
8. The processing method of raw materials of the spleen-tonifying and lung-benefiting pill as claimed in claim 7, wherein the preparation method of the mare's milk poria cocos is as follows: the preparation method of the mare milk poria cocos comprises the following steps: taking the poria blocks, putting the poria blocks into a frying container, and heating the poria blocks by slow fire; taking horse milk, and mixing the horse milk with poria cocos and the horse milk according to the solid-to-liquid ratio (6-8): 1(kg/L), spraying horse milk while parching, mixing, taking out, and cooling.
9. A finished dosage form prepared from the traditional Chinese medicine composition of the spleen-tonifying and lung-benefiting pill as claimed in any one of claims 1 to 8, wherein the finished dosage form comprises pills, tablets, granules, paste or powder.
10. A method for preparing a traditional Chinese medicine pill for tonifying spleen and benefiting lung according to claim 9, which comprises the following steps:
(1) processing raw materials:
weighing the following raw materials in parts by weight: 75-225 g of codonopsis pilosula, 75-225 g of Chinese yam, 40-120 g of astragalus, 40-120 g of poria cocos processed with mare's milk, 15-45 g of fructus amomi preparata, 15-45 g of rhizoma atractylodis fried with sesame oil, 20-60 g of radix ophiopogonis, 30-90 g of bighead atractylodes rhizome, 15-45 g of schisandra chinensis, 20-60 g of lotus seed, 20-60 g of Chinese date and 10-30 g of liquorice. Crushing the raw materials of each component into fine powder by using a crusher respectively, sieving the fine powder by using a sieve of 100-200 meshes, and uniformly mixing the medicinal powder of each component for later use;
(2) processing auxiliary materials-refining honey:
pouring honey into a honey refining pot for refining honey, boiling the honey with strong fire, removing froth impurities, refining with slow fire until the honey is orange yellow;
(3) preparation of the pill:
A. blank preparation: weighing the weight of the mixed medicinal powder, and mixing the medicinal powder and the honey according to the solid-liquid ratio of 1: (1.1-1.5), slowly and discontinuously pouring the honey into the mixed medicinal powder while stirring, and when the dry medicinal powder is basically not seen, continuously mixing and stirring to fully and uniformly mix the honey and the medicinal powder, and pouring the honey into a clean container to knead the honey into blanks;
B. pelleting: cutting the prepared honey base into a plurality of equal parts; twisting each honey blank into a strip shape, wherein the cross section diameter of the twisted medicine strip is 1-2 cm; cutting the medicine strip into a plurality of small pills with the weight of 11 +/-1 g; finally kneading into pills, bagging and packaging. The traditional Chinese medicine pill for tonifying spleen and benefiting lung is obtained.
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Application publication date: 20211207 |