CN112755138A - Qi-tonifying and spleen-tonifying lollipop and preparation method thereof - Google Patents
Qi-tonifying and spleen-tonifying lollipop and preparation method thereof Download PDFInfo
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Classifications
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K35/56—Materials from animals other than mammals
- A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
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- A—HUMAN NECESSITIES
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- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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- A61K2236/30—Extraction of the material
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- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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Abstract
The invention discloses a qi-tonifying and spleen-invigorating lollipop which comprises the following raw materials in parts by mass: 7-10 parts of radix pseudostellariae; 7-13 parts of bighead atractylodes rhizome; 7-13 parts of poria cocos; 10-17 parts of Chinese date; 7-13 parts of endothelium corneum gigeriae galli; 7-13 parts of malt; 7-13 parts of medicated leaven; 7-10 parts of immature bitter orange; 7-10 parts of dried orange peel; 7-10 parts of liquorice, and the preparation method comprises the following steps: repeatedly decocting for 3 times according to a conventional traditional Chinese medicine decoction method, finally combining the decoctions for 3 times, filtering by using a 160-mesh filter screen to obtain filtrate, concentrating the filtrate into clear paste, adding crushed maltose and crystal sugar in a ratio of 50: 2, stirring for about 30min, decocting with slow fire until fine bubbles exist and the bubbles are not easy to fade out after stirring, putting a sterile paper stick into a mold, filling the mold with a small spoon of syrup, and cooling and demolding the syrup to obtain the qi-tonifying and spleen-tonifying lollipop. Clinical efficacy tests prove that the traditional Chinese medicine composition has better treatment effect on patients who lose health after spleen transportation, the average effective rate is 97.5 percent in the treatment process, and the treatment effect is obvious.
Description
Technical Field
The invention relates to the technical field of medicines, and particularly relates to a qi-tonifying and spleen-invigorating lollipop and a preparation method thereof.
Background
The children are easy to lose the spleen transportation and health due to age, development and other reasons, and are mostly characterized by lusterless complexion, no appetite or food odor, refusal to eat, emaciation and mental state without special abnormality, basically normal defecation and urination, white or thin and greasy tongue coating and forceful pulse. The kidney is the innate root, the spleen is the acquired root, the five flavors cannot be known if the spleen is not harmonized, the infant is in the vigorous growth and development period, the spleen is healthy and transported, and essence and micro powder are spread to generate qi and blood, nourish the five internal organs and six internal organs, and make the four limbs and bones. At present, children who lose health in spleen transportation are mostly treated by traditional Chinese medicine decoction, ointment formula and patent medicine, but the traditional Chinese medicine decoction, the ointment formula and the patent medicine can not achieve good effects. For example, children often reject the decoction and the ointment when taking the decoction and the ointment, the phenomena of nausea and vomiting and the like are often caused when children reject the decoction and the ointment, swallowing difficulty and incapability of insisting after taking the patent medicine occur, so that the economic burden of patients is caused by the waste of medicinal materials, the disease condition is delayed due to the influence of the curative effect, and the optimal treatment time is missed. In view of this, we have taken measures such as: when the traditional Chinese medicine decoction is taken, some sugar is added to change the taste, or the traditional Chinese medicine decoction is diluted by water or taken for multiple times, but the traditional Chinese medicine decoction is not satisfactory.
At present, no Chinese medicine dosage form is favored by children. Therefore, how to provide a lollipop dosage form which is easy to accept by children and convenient to take and is used for treating children to replenish qi and invigorate spleen becomes a long-term technical appeal for technical personnel in the field.
In view of the characteristics of difficulty in taking traditional Chinese medicine decoction, paste formula, patent medicine and the like by children, the applicant innovates the mode of taking traditional Chinese medicine by children, and combines the psychological characteristics of children to prepare the traditional Chinese medicine decoction, paste formula, patent medicine and the like which are inconvenient for children to take into various cartoon-shaped qi-tonifying and spleen-tonifying lollipops which are liked by children.
Disclosure of Invention
The invention aims to overcome the defects in the background technology and provide a lollipop capable of tonifying qi and spleen.
The technical scheme for solving the technical problems is that the traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by mass:
7-10 parts of radix pseudostellariae; 7-13 parts of bighead atractylodes rhizome; 7-13 parts of poria cocos; 10-17 parts of Chinese date; 7-13 parts of endothelium corneum gigeriae galli; 7-13 parts of malt; 7-13 parts of medicated leaven; 7-10 parts of immature bitter orange; 7-10 parts of dried orange peel; and 7-10 parts of liquorice.
The lollipop for tonifying qi and spleen is prepared from the following traditional Chinese medicine raw materials in the optimal mass part ratio:
9 parts of radix pseudostellariae; 10 parts of bighead atractylodes rhizome; 10 parts of poria cocos; 14 parts of Chinese dates; 10 parts of endothelium corneum gigeriae galli; 10 parts of malt; 10 parts of medicated leaven; 9 parts of immature bitter orange; 9 parts of dried orange peel; and 9 parts of liquorice.
Further, the white atractylodes rhizome is stir-fried with bran;
further, the poria cocos is white poria cocos;
further, the endothelium corneum gigeriae galli is fried endothelium corneum gigeriae galli;
further, the malt is fried malt;
further, the medicated leaven is fried medicated leaven;
further, the licorice is prepared licorice.
The preparation method of the lollipop with the effects of tonifying qi and strengthening spleen comprises the following steps:
firstly, mixing the pseudostellaria root, the bighead atractylodes rhizome, the poria cocos, the Chinese date, the endothelium corneum gigeriae galli, the malt, the medicated leaven, the immature bitter orange, the dried orange peel and the liquorice in parts by mass, then putting the mixture into a stainless steel decoction pot, adding water to a position 2 cm higher than the medicine surface, soaking for 120-180 min, putting the decoction pot on a natural gas stove, firstly decocting the mixture with strong fire until the mixture is boiled, decocting the mixture with slow fire for 120-180 min after the mixture is boiled, then removing the residues, taking the decoction, repeatedly decocting the decoction for 3 times, finally combining all the decoction, filtering all the combined decoction by adopting a 160-mesh filter screen to obtain filtrate, concentrating the filtrate into clear paste, adding crushed maltose and rock candy in a ratio of 50: 2, stirring for about 30min, decocting with slow fire to obtain sugar with viscous degree, having many fine bubbles, stirring, dripping into cold water to harden, placing sterile paper stick into mold, filling the mold with syrup with a spoon, cooling to zero deg.C for 3min, and demolding to obtain the final product.
The weight of each lollipop for tonifying qi and spleen is 3-5 g.
The ratio of the clear paste to the crystal sugar to the maltose is 50: 5 parts during preparation of the qi-tonifying and spleen-tonifying lollipop.
The rock candy is a single crystal rock candy; the maltose is water-containing beta-maltose.
By adopting the technical scheme, the invention has the beneficial effects that:
the radix pseudostellariae, the bighead atractylodes rhizome and the poria cocos are mild in drug property, and have the effects of tonifying qi, promoting the production of body fluid, excreting dampness and strengthening spleen; the dried orange peel has the effects of regulating qi and regulating middle warmer, the immature bitter orange has the effects of removing food retention and relieving stuffiness, the chicken's gizzard-membrane has the effects of activating spleen and promoting digestion, the medicated leaven has the effects of promoting digestion and harmonizing stomach, the roasted malt has the effects of promoting digestion and regulating the middle warmer, the Chinese date and the liquorice have the effects of tonifying middle warmer and qi and relieving drug properties, and the medicines are used together, so that the effects of tonifying; meanwhile, the qi-tonifying and spleen-invigorating lollipop has the advantages of high drug concentration, small volume, various shapes, stable drug effect, convenience in taking, good taste, deep enjoyment of children, convenience in carrying, convenience in popularization and the like.
Detailed Description
The present invention will be explained in more detail by the following examples, but the present invention is not limited to the following examples.
The invention relates to a qi-tonifying and spleen-invigorating lollipop which is prepared from the following traditional Chinese medicine raw materials in parts by mass:
7-10 parts of radix pseudostellariae; 7-13 parts of bighead atractylodes rhizome; 7-13 parts of poria cocos; 10-17 parts of Chinese date; 7-13 parts of endothelium corneum gigeriae galli; 7-13 parts of malt; 7-13 parts of medicated leaven; 7-10 parts of immature bitter orange; 7-10 parts of dried orange peel; and 7-10 parts of liquorice.
Wherein the Atractylodis rhizoma is bran parched Atractylodis rhizoma, Poria is Poria, endothelium corneum Gigeriae Galli is parched endothelium corneum Gigeriae Galli, fructus Hordei Germinatus is parched fructus Hordei Germinatus, Massa Medicata Fermentata is parched Massa Medicata Fermentata, and Glycyrrhrizae radix is radix Glycyrrhizae Preparata.
The optimal mass ratio of the traditional Chinese medicine raw materials for preparing the medicine is as follows:
9 parts of radix pseudostellariae; 10 parts of bighead atractylodes rhizome; 10 parts of poria cocos; 14 parts of Chinese dates; 10 parts of endothelium corneum gigeriae galli; 10 parts of malt; 10 parts of medicated leaven; 9 parts of immature bitter orange; 9 parts of dried orange peel; and 9 parts of liquorice.
The invention relates to a preparation method of a lollipop capable of tonifying qi and spleen, which comprises the following steps:
step one, preparing a formula: firstly, Chinese herbal pieces of radix pseudostellariae, bighead atractylodes rhizome, poria cocos, Chinese date, endothelium corneum gigeriae galli, malt, medicated leaven, immature bitter orange, dried orange peel and liquorice are mixed with auxiliary materials of crystal sugar and maltose to be subpackaged.
Soaking in a second step: checking the matched medicines once, putting the medicines into a clean container with the same volume, adding water 2 cm higher than the medicine surface to soak the medicines, fully absorbing and expanding the medicines, and soaking for 120-180 min.
Step three, decocting: decocting the soaked materials with fire. Boiling with strong fire, decocting with slow fire for 120-180 min, concentrating the decoction, pouring out the first decoction with a 160-mesh filter screen, adding clear water to soak the original residue, and decocting with the same method for the second decoction, wherein the smell is light when the third decoction is carried out, and the decoction is filtered completely, and then the residue is discarded. Mixing the decoctions, standing, precipitating, and filtering to obtain the final product with less residue.
Step four, concentration: the filtered medicine juice is poured into a pot for concentration, the medicine juice can be decocted for 240min by strong fire firstly, the water evaporation is accelerated, floating foam is skimmed at any time, the medicine juice slowly becomes thick, then the medicine juice is further decocted for 120min by small fire for concentration, the stirring is continuously carried out at the moment, the medicine juice is extremely easy to stick to the bottom and scorch when being thickened, the medicine juice is stirred until the medicine juice is not scattered on paper, the decocting can be suspended at the moment, and the medicine juice is the clear paste formed by concentration.
Step five, paste collection: adding crystal sugar and maltose into the fluid extract at a ratio of 50: 5, decocting over slow fire for about 30min, stirring with a shovel continuously to make the decocted syrup have many fine bubbles and not fade easily after stirring, and instantly hardening after dropping into cold water.
Step six, forming: and (3) placing the sterile paper lollipop into a mold, filling the mold with syrup by using a small spoon, and demolding to obtain the qi-tonifying and spleen-invigorating lollipop after the syrup is cooled to zero ℃ for 3min, wherein each lollipop contains 3-5 g of lollipop.
Step seven, packaging and storing: packaging with plastic bag in a working room after ultraviolet sterilization for 60min, sealing, and storing in a cool and dry place.
When the invention is used for treatment, only one lollipop is needed to be taken each time, so that the lollipop is easy to accept and take by children, can persist in the treatment course, has no adverse reaction, greatly reduces the medical cost and saves social resources. In addition, the invention can tightly buckle the current pathogenesis of spleen dysfunction of children, starts with the prescription of 'tonifying qi and spleen and promoting digestion and relieving stasis' and prepares the lollipop for the children with spleen dysfunction. The final purpose of the invention is to enable children patients who have lusterless complexion, no appetite or no taste of food, refusal to eat, thin and thin body but no special abnormality in mental state, normal stool and urine basically, white or thin and greasy tongue coating and forceful pulse to recover health as soon as possible by taking the qi-tonifying and spleen-tonifying lollipop, thereby embodying the clinical advantages of the qi-tonifying and spleen-tonifying lollipop.
The invention treats the children who are unhealthy in spleen transportation, and 30 children in the group are treated before and after taking the medicine
The clinical curative effect and the drug safety are evaluated by the set observation indexes, so that the clinical curative effect of the invention is further researched and confirmed.
The efficacy test is as follows:
test drugs: the medicine of the invention is a lollipop for replenishing qi and invigorating spleen, 4 g per stick, and each stick contains g of raw material medicine.
Clinical data: 120 patients with spleen dysfunction are treated by the traditional Chinese medicine composition, wherein the age of the patients is 10 years at most, and the age of the patients is 4 years at least.
Diagnostic criteria:
1. the face is lusterless, the spirit is soft, the food is not thought or tasteless, and the people refuse to eat the food.
2. Anorexia, restlessness, and emaciation.
3. Stool and urine are basically normal, the tongue coating is white or thin and greasy, and the pulse is still forceful.
The treatment method comprises the following steps: the preparation is taken once a day, one lollipop each time, for 30 days.
The evaluation standard of the curative effect is as follows:
(1) children like to insist on taking the medicine.
(2) The appetite is increased and the anorexia symptom is relieved.
(3) Defecation is normal.
(4) The body weight is increased.
(5) The complexion changes.
The curative effect is as follows:
(1) children like to insist on taking the medicine.
(2) The appetite is increased, the appetite is normal, and the anorexia is cured.
(3) Strong body and ruddy complexion.
(4) During the period, no cold and fever occur.
The evaluation standard of the curative effect is as follows:
and (3) curing: the functions of the children are recovered to normal after taking food and human body, the children are spiritual and have spiritual vigor, ears and eyes are wonderful, the expression is lively, the face color is ruddy, the breathing is even, and the bowels are normal.
Improvement: improve the functions of both food and human body.
The disease is not cured: the function of the human body is not improved after receiving food.
Typical cases are:
1. when a woman is in 8 years old and goes to our hospital in 2018 months, anorexia is diagnosed, the clinical symptoms are lusterless complexion, no appetite is thought or food is tasteless, the woman refuses to eat, the body is thin and thin, the mental state is generally not special abnormal, the urine and the stool are basically normal, the tongue coating is white or thin and greasy, and the pulse is still powerful. After the traditional Chinese medicine is taken for 1 course, the symptoms are obviously improved, and the medicine is healed and recovered to be normal after the medicine is taken for 2 courses; follow-up after 3 months without recurrence.
2. After the patient takes the traditional Chinese medicine composition for 2 treatment courses, the symptoms are obviously improved, and the patient can be healed and recovered to be normal after taking the traditional Chinese medicine composition for 1 treatment course; follow-up after 3 months without recurrence.
3. When a patient is diagnosed in 6 years old in 2019 and 10 months, listlessness, absence of spirit, dull complexion, fatigue, sleepiness, dull expression and poor appetite of the patient are not improved. After the medicine is taken for 2 courses, the symptoms are relieved, the medicine is continuously taken for 2 courses, the symptoms disappear, and the follow-up is carried out after 3 months without relapse.
4. The patient is diagnosed with anorexia, mental fatigue, anorexia, dysphoria and emaciation in 2019 for 8 months after being cured, and the symptoms disappear after taking the traditional Chinese medicine preparation for 2 courses of treatment. Follow-up after 3 months without recurrence.
5. The patient has a certain plum age of 10 years, has speckles before taking, is emaciated in body, is tired, is not easy to talk, is poor in appetite, has relieved symptoms after taking for 2 treatment courses, has disappeared symptoms after continuing taking for 1 treatment course, and is relapsed after 3 months.
6. The patient is higher, 6 years old, and suffers from listlessness, no spirit in eyes, dark complexion, fatigue, sleepiness, expression dull and no appetite in 11 months in 2018, the symptoms are relieved after taking the traditional Chinese medicine preparation for 2 treatment courses, the symptoms are relieved after taking the traditional Chinese medicine preparation for 1 treatment course, and the return visit symptoms are relieved after 3 months.
The treatment results are as follows: the results of the treatment are shown in Table 1
Table 1 shows the results of the tests carried out by the present invention
As can be seen from Table 1, the average effective rate is 97.5% in the treatment process, and the treatment effect is remarkable. Test results show that the traditional Chinese medicine composition has the function of treating spleen dysfunction.
The specification of the invention is as follows: the lollipops of the present invention each weigh 4 grams.
The usage and dosage of the invention are as follows: 1 time daily, 1 time.
The storage of the invention: sealing, storing in a cool and dry place.
The validity period of the invention is as follows: for 1 year.
Claims (4)
1. The qi-tonifying and spleen-invigorating lollipop is characterized by comprising the following traditional Chinese medicine raw materials in parts by mass:
7-10 parts of radix pseudostellariae; 7-13 parts of bighead atractylodes rhizome; 7-13 parts of poria cocos; 10-17 parts of Chinese date; 7-13 parts of endothelium corneum gigeriae galli; 7-13 parts of malt; 7-13 parts of medicated leaven; 7-10 parts of immature bitter orange; 7-10 parts of dried orange peel; and 7-10 parts of liquorice.
2. The lollipop with effects of replenishing qi to invigorate the spleen as claimed in claim 1, wherein the traditional Chinese medicine raw materials are prepared from the following raw materials in parts by mass:
9 parts of radix pseudostellariae; 10 parts of bighead atractylodes rhizome; 10 parts of poria cocos; 14 parts of Chinese dates; 10 parts of endothelium corneum gigeriae galli; 10 parts of malt; 10 parts of medicated leaven; 9 parts of immature bitter orange; 9 parts of dried orange peel; and 9 parts of liquorice.
3. A preparation method of a lollipop capable of tonifying qi and spleen is characterized by comprising the following steps: the preparation method comprises the following steps according to the mass ratio of the traditional Chinese medicine raw materials of claim 2:
step one, preparing a formula: firstly, Chinese herbal pieces of radix pseudostellariae, bighead atractylodes rhizome, poria cocos, Chinese date, endothelium corneum gigeriae galli, malt, medicated leaven, immature bitter orange, dried orange peel and liquorice are mixed with auxiliary materials of crystal sugar and maltose to be subpackaged.
Soaking in a second step: checking the matched medicines once, putting the medicines into a clean container with the same volume, adding water 2 cm higher than the medicine surface to soak the medicines, fully absorbing and expanding the medicines, and soaking for 120-180 min.
Step three, decocting: decocting the soaked materials with fire. Boiling with strong fire, decocting with slow fire for 120-180 min, concentrating the decoction, pouring out the first decoction with a 160-mesh filter screen, adding clear water to soak the original residue, and decocting with the same method for the second decoction, wherein the smell is light when the third decoction is carried out, and the decoction is filtered completely, and then the residue is discarded. Mixing the decoctions, standing, precipitating, and filtering to obtain the final product with less residue.
Step four, concentration: the filtered medicine juice is poured into a pot for concentration, the medicine juice can be decocted for 240min by strong fire firstly, the water evaporation is accelerated, floating foam is skimmed at any time, the medicine juice slowly becomes thick, then the medicine juice is further decocted for 120min by small fire for concentration, the stirring is continuously carried out at the moment, the medicine juice is extremely easy to stick to the bottom and scorch when being thickened, the medicine juice is stirred until the medicine juice is not scattered on paper, the decocting can be suspended at the moment, and the medicine juice is the clear paste formed by concentration.
Step five, paste collection: adding crystal sugar and maltose into the fluid extract at a ratio of 50: 2, decocting over slow fire for about 30min, stirring with a shovel continuously to make the decocted syrup have many fine bubbles and not fade easily after stirring, and instantly hardening after dropping into cold water.
Step six, forming: and (3) placing the sterile paper lollipop into a mold, filling the mold with syrup by using a small spoon, and demolding to obtain the qi-tonifying and spleen-invigorating lollipop after the syrup is cooled to zero ℃ for 3min, wherein each lollipop contains 3-5 g of lollipop.
Step seven, packaging and storing: packaging with plastic bag in a working room after ultraviolet sterilization for 60min, sealing, and storing in a cool and dry place.
4. The preparation method of the lollipop for replenishing qi to invigorate the spleen according to claim 3, wherein the lollipop comprises the following steps: the rock candy is a single crystal rock candy; the maltose is water-containing beta-maltose.
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| CN115777825A (en) * | 2021-09-10 | 2023-03-14 | 大连正源中医门诊部有限公司 | Eight-treasure lollipop and production process thereof |
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