CN110812468B - Gymnadenia conopsea-37-flavor Mongolian medicinal ointment formula and preparation method thereof - Google Patents

Abstract

The invention discloses a conic gymnadenia tuber-37 Mongolian medicinal ointment formula and a preparation method thereof, wherein the formula is prepared from the following medicinal components in parts by weight: 50g of northern calcite, 50g of conic gymnadenia rhizome, 50g of pomegranate, 50g of myrobalan, 50g of dried white grape, 25g of round cardamom, 25g of areca nut, 25g of trogopterus dung, 25g of crab, 25g of black borneol, 20g of long pepper, 20g of sealwort, 20g of asparagus cochinchinensis, 15g of polygonatum odoratum, 15g of cinnamon, 15g of dried ginger, 15g of mirabilis jalapa root, 15g of caltrop, 15g of nutmeg, 15g of agilawood, 15g of common rhododendron leaf, 15g of dalbergia wood, 15g of cluster mallow seed, 15g of white pepper, 10g of caoguo, 10g of fructus choerospondiatis, 10g of sword bean, 10g of sal ammoniac, 10g of hot pepper, 5g of flos caryophylli, 5g of asafetida, 5g of notopterygium root, 150g of white sugar or crystal sugar, 250g of brown sugar, 50g of honey, 100ml of milk wine and 5ml of sesame oil. The medicine composition has obvious curative effect, treats both principal and secondary aspects of diseases, has no toxic or side effect, and has obvious curative effect on dizziness and tinnitus, insomnia and dreaminess, palpitation and shortness of breath, aversion to cold, cold limbs, hectic fever and sweating, soreness and weakness of waist and knees and other diseases caused by deficiency of both yin and yang.

Description

Gymnadenia conopsea-37-flavor Mongolian medicinal ointment formula and preparation method thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicines, in particular to a conic gymnadenia tuber-37 Mongolian medicinal ointment formula and an ointment preparation method thereof.

Background

Kidney deficiency refers to the deficiency of kidney essence, qi, yin and yang. There are many kinds of kidney deficiency, and the most common of them is kidney yin deficiency and kidney yang deficiency. Symptoms of kidney-yang deficiency include soreness of waist, cold limbs, intolerance of cold, even edema, and cold, and the deficiency of kidney-yang can also lead to poor sexual function; the symptom of kidney yin deficiency is "heat", and mainly includes soreness of waist, dryness-heat, night sweat, sweating due to debility, dizziness, tinnitus, etc. Modern science proves that when people suffer from kidney deficiency, the immunity of people is reduced no matter the kidney is yin deficient or the kidney is yang deficient, and more evidence shows that when the kidney deficiency occurs, the immunity of the kidney is reduced, the microcirculation system of the kidney is also blocked, and the kidney collaterals are blocked. Therefore, the treatment of kidney deficiency should be combined with prevention and treatment.

Generally speaking, waist sleepiness, night sweat, premature ejaculation and sexual hypofunction are considered as kidney yin deficiency, a lot of people take pills of six ingredients with rehmannia by themselves, but the effects are not always good, and some pills with golden taste and kidney qi are taken orally, the effect is not ideal; modern people change the human body along with changes of natural environment, social environment, family environment, diet types, psychological factors and the like, for example, the human body generally becomes fat, generally becomes young and the like, so that the patients with kidney-yang deficiency are increasingly increased due to changes of indigestion, blood turbidity, metabolic disorder, insufficient clarity and the like; at present, a plurality of Chinese patent medicines for treating kidney-yang deficiency have certain curative effect for treating kidney-yang deficiency, but the Chinese patent medicines have the defects of not accurate curative effect, failing to treat both symptoms and root causes and the like in different degrees.

The prior conic gymnadenia tuber-37 medicine generally adopts the preparation mode and the taking mode of pills or powder, and the traditional powder comprises the following components: the taste is poor, and the medicine is not easy to take; the milk wine is easy to volatilize, and the components are easy to lose; white sugar, brown sugar, honey, dried white grapes, milk wine and other high-viscosity components which are not easy to crush and dry in the sun to prepare powder; the crude drugs are abundant, and some of the drugs have certain stimulation response to the stomach and intestine (such as abdominal discomfort, heartburn, nausea and the like) in long-term service.

Traditional pill preparation: has poor digestion function, and is not easy to digest and absorb the effective components of the pill for the patients with weak health.

Disclosure of Invention

Aiming at the problems, the invention aims to provide a pharmaceutical composition for treating kidney-yang deficiency and a paste preparation method thereof, wherein the pharmaceutical composition has the advantages of obvious curative effect, treatment of both symptoms and root causes, and no toxic or side effect.

In order to achieve the purpose, the technical scheme adopted by the invention is as follows:

the formula of the gymnadenia conopsea-37-flavor Mongolian ointment is characterized in that the medicinal composition is prepared from the following medicinal components in parts by weight:

main materials: 45-55g of conic gymnadenia rhizome, 45-55g of pomegranate, 45-55g of myrobalan, 45-55g of dried white grape, 20-30 g of round cardamom, 20-30 g of areca nut, 20-30 g of trogopterus dung, 20-30 g of crab, 20-30 g of borneol, 18-22 g of long pepper, 18-22 g of rhizoma polygonati, 18-22 g of asparagus cochinchinensis, 12-18g of polygonatum odoratum, 12-18g of cinnamon, 12-18g of dried ginger, 12-18g of mirabilis jalapa root, 12-18g of tribulus terrestris, 12-18g of nutmeg, 12-18g of rhododendron, 12-18g of chingma abutilon seed, 12-18g of white pepper, 8-12g of tsaoko kernel, 8-12g of fructus choerospondiatis, 8-12g of hot pepper, 4-8g of flos caryophylli, 8-12g of sword bean, 4-6 ml of red sesame oil, 45-55g of calcite, 12-18g of agilawood, 12-18g of rosewood, 8-4 g of white sugar or 145 g of white sugar, 250g of brown sugar 245-.

Preferably, the pharmaceutical composition comprises the following main materials in parts by weight:

50g of conic gymnadenia rhizome, 50g of pomegranate, 50g of myrobalan, 50g of dried white grape, 25g of round cardamom, 25g of areca nut, 25g of trogopterus dung, 25g of crab, 25g of borneol, 20g of long pepper, 20g of rhizoma polygonati, 20g of asparagus cochinchinensis, 15g of polygonatum odoratum, 15g of cinnamon, 15g of dried ginger, 15g of mirabilis jalapa root, 15g of caltrop, 15g of nutmeg, 15g of common rhododendron leaf, 15g of cluster mallow, 15g of white pepper, 10g of grass nut, 10g of fructus choerospondiatis, 10g of hot pepper, 5g of flos caryophylli, 10g of sword bean, 5ml of sesame oil, 50g of northern glauber rock, 15g of agilawood, 15g of rosewood, 5g of purple sal, 5g of asafetida, 5g of notopterygium root, 150g of white sugar or rock sugar, 250g of brown sugar, 50g of honey and 100ml of milk wine.

A preparation method of a formula of conic gymnadenia rhizome-37 Mongolian medicinal ointment comprises the following steps:

s1, weighing 45-55g of conic gymnadenia rhizome, 45-55g of pomegranate, 45-55g of myrobalan, 45-55g of dried white grape, 22.5-27.5 g of northern calcite, 20-30 g of round cardamom, 20-30 g of areca nut, 20-30 g of trogopterus dung, 20-30 g of crab, 20-30 g of borneol, 18-22 g of long pepper, 18-22 g of rhizoma polygonati, 18-22 g of asparagus, 12-18g of radix polygonati officinalis, 12-18g of cinnamon, 12-18g of dried ginger, 12-18g of mirabilis root, 12-18g of caltrop, 12-18g of nutmeg, 12-18g of common rhododendron rhizome, 12-18g of cluster mallow fruit, 12-18g of white pepper, 8-12g of cayenne kernel, 8-12g of fructus choerospondiatis, 8-12g of hot pepper, 4-6 g of purple arenaceous litum, 4-8g of clove bud and 8-12g of sword bean, adding water to soak for 12 hours, and adding 1.5-2 times of water according to the formula weight;

s2, decocting the soaked medicines for three times, and mixing and containing liquid medicines decocted for three times;

s3, standing and precipitating the decocted liquid medicine, and filtering by using gauze;

s4, decocting the filtered liquid medicine to be thick by three stages of strong fire, medium fire and slow fire;

s5, adding 4-6 ml of sesame oil, 22.5-27.5 g of north gypsum rubrum, 12-18g of agilawood, 12-18g of dalbergia wood, 4-6 g of sal ammoniac, 4-8g of asafetida, 4-8g of notopterygium, 155g of white sugar or rock sugar 145-plus, 250g of brown sugar 245-plus, 45-55g of honey and 90-110ml of milk wine into the thick paste liquid medicine, and collecting the paste by small fire;

and S6, placing the prepared ointment prescription into a sealed container, and placing the sealed container into a refrigerator for storage.

As a further improvement of the invention, in the step S2, three times of decoction are carried out, wherein no water is added in the first time of decoction, 6 times of medicine water is added in the second time of decoction, 3 times of medicine water is added in the third time of decoction, and the time of each time of decoction is 1 hour.

As a further improvement of the invention, in the step S3, the temperature of the slow fire stage is 150-.

As a further improvement of the invention, the ointment in step S6 is preserved in a sealed manner at a temperature of 4 ℃.

Northern glauberite: removing dampness, removing heat, stopping vomiting, relieving diarrhea, resolving food stagnation, relieving distension and fullness, tonifying, eliminating edema, removing toxic substances, setting bone, and regulating body fluid.

Palm ginseng: nourishing essence, and can be used for treating spermatorrhea, menorrhagia, and asthenia.

Pomegranate: tonifying fire, expelling pathogenic wind, relieving dryness and cold, resolving food stagnation, stimulating appetite, and relieving diarrhea.

Myrobalan fruit: removing symptoms and pathological changes, removing toxic substances, and regulating body fluid.

Raisin: dispelling lung heat, relieving cough, relieving asthma, and regulating body fluid.

Tapping: dispelling kidney cold, relieving Heryi, invigorating fire, resolving food stagnation, promoting appetite, and stopping vomiting.

Betel nut: nourishing kidney, expelling parasites, and nourishing teeth.

Trogopterus dung: removing heat, relieving pain, relieving lymphadenectasis, and regulating body volume

Crab processing: induce diuresis and resolve edema.

Black borneol: removing Hila, eliminating indigestion, killing sticky, and disintegrating masses.

Long pepper picking: tonifying fire, removing cataplasma, regulating body fluid, supporting yang, relieving asthma, eliminating phlegm, and relieving pain.

Rhizoma polygonati: nourishing, strengthening yang, dryness and pus, and blackening hair.

Asparagus: nourishing, tonifying yang, stopping nocturnal emission, eliminating NIUDUSU, relieving HEYI, and eliminating old hidden heat.

Fragrant solomonseal rhizome: nourishing, dryness coordinating with Niuhusu, removing kidney cold HEYI, and invigorating stomach fire.

Cinnamon: dispelling cold, nourishing fire, relieving diarrhea, and suppurating

Dried ginger: tonifying fire, promoting digestion, stimulating appetite, and removing bara and dryness of heryi

Radix Mirabilis: dispelling kidney cold, dryness, relieving superficies, removing calculus and oppression

Caltrop fruit: dispelling kidney cold, strengthening yang, promoting urination, and eliminating edema

Nutmeg: zhenhei, Buxie, Xiaoshi and appetizing

Agilawood: relieving heryi, dispelling heat and relieving stabbing pain

Turning to white: removing dryness, tonifying fire, eliminating edema, relieving stabbing pain, relieving cough, eliminating phlegm, nourishing, and regulating body volume

And (3) rosewood heart wood: zhenhei, dispel heat and alleviate stabbing pain.

Mallow seeds: dredging vessels, promoting urination, eliminating edema, promoting pus discharge, relieving diarrhea, quenching thirst

White pepper: tonify fire, promote digestion, stimulate appetite, dispel the dryness and cold.

And (3) nutlet: removing spleen and stomach cold, tonifying fire, and promoting digestion

Fructus Choerospondiatis: dispelling heart-heat and nourishing heart

Cutting beans: dispel kidney heat and nourish kidney.

Cyanide: tonifying fire, relieving hyperactive liver, relieving constipation, relieving spasm, and relieving stabbing pain

Hot pepper: tonify fire, break stuffiness, relieve edema, scrofula and kill parasites.

Flos caryophyllata: dispelling cold, benefiting throat, invigorating fire, resolving food stagnation, promoting appetite, removing toxic substance, promoting eruption

Asafetida: relieving heryi, killing parasite, relieving stabbing pain, invigorating fire, resolving food stagnation, and stimulating appetite

Notopterygium: strengthening yang, nourishing vital essence and qi, and dispelling kidney cold

Sesame: tranquilizing, moistening skin, tonifying yang, relieving oppression, tonifying fire, and tranquilizing.

White sugar or rock sugar: dispel heat, stop vomiting, moisten five sense organs, quench thirst.

Brown sugar: dispelling cold, strengthening yang, increasing weight, and relieving diarrhea.

Honey: removing dampness, removing toxic substance, promoting pus discharge, nourishing, and healing wound.

Milk wine: dispelling cold, promoting blood circulation, and tonifying.

The invention has the beneficial effects that: the medicine has obvious treatment effect on dizziness and tinnitus, insomnia and dreaminess, palpitation and shortness of breath, intolerance of cold and cold limbs, hectic fever and sweating, soreness and weakness of waist and knees and other diseases caused by deficiency of both yin and yang.

The medicine has obvious treatment effect on waist soreness, cold limbs, intolerance of cold, even edema and poor sexual function caused by kidney-yang deficiency, and also has effect on symptoms of kidney-yin deficiency, such as waist soreness, dryness-heat, night sweat, deficient sweat, dizziness, tinnitus and the like. The traditional preparation has the functions of dispelling cold, calming the nerves, warming and tonifying, and the like; it is mainly used for treating cold syndrome, such as dyspepsia due to stomach cold, gastrectasia and gastralgia, soreness and weakness of waist and knees, night sweat, cold limbs, edema of face, sexual hypofunction, cough, expectoration, and breath holding caused by lung qi disease, dyspepsia and chronic diarrhea caused by liver cold, palpitation, short breath, restlessness, insomnia caused by heart Heryi disease, hemorrhoid, pudendal pyocutaneous disease, pollakisuria, rheumatic disease, asthenia, emaciation, malnutrition, male sexual hypofunction, and female leukorrhagia.

The application improves the traditional formulation of honeyed pills into a paste formula through a new idea, so that the absorption of active ingredients of the medicine is increased, the treatment effect of the medicine is improved, particularly the nourishing function is increased, the treatment effect on the sexual hypofunction is obviously improved, and the medicine has treatment effects on dizziness and tinnitus, insomnia and dreaminess, palpitation and shortness of breath, intolerance of cold and cold limbs, hectic fever and sweating, soreness and weakness of waist and knees and other diseases caused by deficiency of yin and yang in traditional Chinese medicine.

Meanwhile, clinical pharmacodynamic research shows that the medicine is suitable for modern kidney tonifying and nourishing and body building medicines, is easy to absorb by a human body after being prepared into a paste formula, and has an increased nourishing effect.

Detailed Description

In order to make those skilled in the art better understand the technical solution of the present invention, the following further describes the technical solution of the present invention with reference to the embodiments.

Example 1:

a formula of conic gymnadenia tuber-37-flavor Mongolian medicinal ointment is prepared from the following medicinal components in parts by weight: 5ml of sesame oil, 50g of northern calcite, 50g of conic gymnadenia rhizome, 50g of pomegranate, 50g of myrobalan fruit, 50g of dried white grape, 25g of white kowter, 25g of areca seed, 25g of trogopterus dung, 25g of crab, 25g of black borneol, 20g of long pepper, 20g of rhizoma polygonati, 20g of asparagus fern, 15g of polygonatum odoratum, 15g of cinnamon, 15g of dried ginger, 15g of mirabilis japonicas, 15g of tribulus terrestris, 15g of nutmeg, 15g of agilawood, 15g of common alstonia, 15g of dalbergia wood, 15g of white pepper, 10g of grass nut, 10g of fructus choerospondiatis, 10g of sal ammoniac, 10g of hot pepper, 5g of flos caryophylli, 10g of sword bean, 5g of asafetida, 5g of notopterygium root, 4-6 ml of red sesame oil, 45-55g of northern calcite, 12-18g of agilawood, 12-18g of dalbergia, 8-12g of violet, 8g of rock candy, 4-8g of brown sugar or 145 g of white sugar, 45-55g of honey and 90-110ml of milk wine.

A preparation method of a formula of conic gymnadenia rhizome-37 Mongolian medicinal ointment comprises the following steps:

s1, weighing 12.5g of northern glauberite, 50g of conic gymnadenia rhizome, 50g of pomegranate, 50g of myrobalan, 50g of white raisin, 25g of white kowter, 25g of areca nut, 25g of trogopterus dung, 25g of crab, 25g of black borneol, 20g of long pepper, 20g of rhizoma polygonati, 20g of asparagus cochinchinensis, 15g of radix polygonati officinalis, 15g of cinnamon, 15g of dried ginger, 15g of mirabilis jalapa, 15g of caltrop, 15g of nutmeg, 15g of shinyleaf pricklyash root, 15g of cluster mallow seed, 15g of white pepper, 10g of caoguo, 10g of fructus choerospondiatis, 5g of sal ammoniac, 10g of hot pepper, 5g of flos caryophylli and 10g of sword bean, adding water to soak for 12 hours according to the formula, increasing the amount of the formula according to the proportion, such as 1.5 times and 2 times;

the water adding amount of the soaked medicine is generally 20 times of the total weight of the decoction pieces, the formula is used for soaking the medicine with the total weight of 595g, and the medicine is soaked in 12L of water;

specifically, the method comprises the following steps: soaking medicinal materials such as conic gymnadenia rhizome, pomegranate, myrobalan, 50g of calcined northern gypsum rubrum of the white raisin, round cardamom, areca-nut, trogopterus dung, crab, 25g of long pepper of the black borneol, rhizoma polygonati, 20g of asparagus cochinchinensis of the asparagus, fragrant solomonseal rhizome, cassia bark, dried ginger, mirabilis jalapa (root), puncturevine caltrop fruit, nutmeg, Chinese ilex leaf (rhododendron seniavinii or rhododendron pulchrum), cluster mallow fruit, 15g of caoguo of the white pepper, fructus choerospondiatis, 10g of red sal ammoniac of the hot pepper and 5g of flos caryophylli. The medicinal materials are soaked for 12 hours generally to fully absorb water, so that the active ingredients in the medicaments can be absorbed;

s2, decocting the soaked medicines for three times, and mixing and containing liquid medicines decocted for three times;

soaking the medicinal materials 20 times, decocting the medicinal materials and the soaking liquid together without adding water for three times, wherein each time of decoction is 1 hour, the first decoction is not added with water, the second decoction is added with 6 times of medicinal water, and the third decoction is added with 3 times of medicinal water, and the decocting process comprises the steps of firstly heating the medicinal materials to 100 ℃ by strong fire at 180-200 ℃, and then heating the medicinal materials for 1 hour by slow fire at 100-120 ℃. Taking out the decoction, and decocting for the next time in the same manner as above;

the specific method comprises the following three decoction medicines: the medicine is immersed by adding water every time, and is not needed to be too much, because the medicinal materials at the moment are fully soaked with water, the medicinal materials are decocted to be boiled firstly, then the medicinal materials are decocted for 20 minutes by using small fire, the medicinal liquid is taken out after filtration, meanwhile, the residual medicinal liquid is squeezed out by using a flat-bottomed bowl with proper size, the medicine residues are added with cold water and decocted again, the operation is repeated for three times, the medicinal liquid is combined, the medicinal liquid is very light when the medicinal liquid reaches the third juice, the medicine residues are just like bean curd residues, and the whole decocting process generally needs 3 hours;

s3, standing and precipitating the liquid medicine, and filtering the liquid medicine by using gauze;

mixing the decocted liquid after the three times of decoction, placing the mixture in a stainless steel barrel for standing for 12 hours, passing the decocted liquid after standing through a 200-mesh filter screen, placing the filtered liquid in a heating container at 180-200 ℃ with strong fire, concentrating, adding 150g of white sugar or rock sugar, 250g of brown sugar, 50g of honey and 100ml of milk wine when the filtered liquid is concentrated to 1/3 ℃ with total filtered liquid, changing to 150 ℃ with slow fire, collecting ointment, stirring the liquid medicine uninterruptedly in the process to avoid the liquid medicine from being burnt, stopping heating when the liquid medicine drops to form beads or hang flags, completing the ointment collection, placing the prepared ointment in a medicine charging container (a sealed bag or a preservation box), and cooling at room temperature;

the essence is specifically concentrated: standing and precipitating the decocted liquid medicine of the three-juice decoction, filtering for 3 times by using 4 layers of gauze, reducing impurities in the liquid medicine as much as possible, putting the filtered liquid medicine into a container with high heat conduction such as a steel pot, decocting, evaporating and concentrating by using strong fire, continuously stirring, preventing overflow, enabling the liquid medicine to gradually form a thick state, generally requiring about 4 hours, concentrating the liquid medicine of a small paste prescription, generally having the amount of about 1 liter, and having sticky feeling during stirring and accompanied with resistance;

s4, decocting the filtered liquid medicine to be thick by three stages of strong fire, medium fire and slow fire;

s5, adding 5ml of sesame oil, 12.5g of north gypsum rubrum, 15g of agilawood, 15g of dalbergia wood, 5g of cyanide, 5g of asafetida and 5g of notopterygium, and collecting the ointment with slow fire;

in the preparation process, the two substances of the north hanshui stone and the purple sal ammoniac are both needed in two steps, and half of the total amount is needed, so that the powder has good curative effect on gastrointestinal diseases, and the decoction is easy to absorb;

s6, placing the prepared ointment prescription into a sealed container, and placing the container into a refrigerator for storage;

specifically, the method comprises the following steps of: adding semen Sesami Indici oil 5ml, crystal sugar, Mel, milk wine, brown sugar, etc. into the thick paste, and concentrating with slow fire; 25g of north gypsum rubrum (calcined), 15g of agilawood, 15g of dalbergia wood, 5g of sal ammoniac, asafetida and notopterygium root, which are respectively decocted into thick juice or ground into fine powder by small fire and added when the ointment is collected; the self-made paste formula can also achieve the effect of dripping water into beads, and if the paste is too thin and thick after being cooled, the paste can be added into a pot to be boiled and evaporated; finally, the prepared ointment is placed in a sealed container and placed in a refrigerator, and the ointment can be taken every day. The medicine is taken one spoon every morning and one spoon each night after one week;

the sealed bagged ointment can be stored for 6 months at room temperature and can be stored for one year at 4 ℃; the fresh-keeping box-packed ointment can be stored for 3 months at room temperature and can be stored for 6 months at 4 ℃.

The formula belongs to an oral nourishing medicine, and the optimal taking time is as follows: the medicine is taken once a spoon (5ml-10ml) in the morning and once a week later, and the dosage is increased to one spoon in the morning and night, with a treatment course of 1-3 months.

The adult can drink a proper amount of warm boiled water before breakfast or sleeping 5-10ml before supper or 5-10ml before fasting before breakfast and sleeping at night respectively after taking the medicine with a small spoon or adding the medicine into warm boiled water for dissolving.

Example 2:

clinical report

1. General data:

2. diagnostic criteria: the syndrome of kidney yang deficiency can be diagnosed according to the Mongolian three diagnostic methods (inquiry, disease symptoms, inspection, general condition, tongue diagnosis, urine image, palpation, mainly pulse taking).

The content of inquiry is as follows: impotence, premature ejaculation, dizziness, tinnitus, insomnia, dreaminess, palpitation, short breath, aversion to cold, cold limbs, cold sweat, soreness of the waist and knees, etc.

Inspection content: pale or pale complexion, no light color, no discharge of food or five more diarrhea, no semen collection, and other weak states; tongue diagnosis: pale and swollen tongue with teeth marks and white coating; urine diagnosis: light color, smell, little urine fog, slow fog dispersion, etc.

Palpation: the deep and thready pulse is common.

3. The treatment method comprises the following steps: one spoon (5ml-10ml) is taken in the morning with empty stomach every day, and one spoon is taken in the morning and at night after one week, with a treatment course of 1-3 months.

4. The treatment effect is as follows: 40 male patients were treated, 32 (30-55 years old), 8 (55 years old) aged, 33, 5, and 2 with obvious effect. The effective rate reaches 95 percent.

Has obvious therapeutic effect on impotence, premature ejaculation, dizziness and tinnitus, insomnia and dreaminess, palpitation and shortness of breath, intolerance of cold and cold limbs, cold sweating, soreness and weakness of waist and knees and other diseases caused by kidney-yang deficiency.

The following are typical cases of treatment with the cream formulation of the present invention:

case 1: name: baxx, male, 32 years old, intraductal mongolian akange city, no history of drug allergy. 2016.12.15 the physician needs to see the doctor in Mongolian medicine. The main complaints are: premature ejaculation, soreness and weakness of waist and knees for more than 2 years; the current medical history: the patients have no obvious induction of sexual life premature ejaculation before 2 years, are easy to fatigue, have difficulty in overcoming, have soreness and weakness of waist and knees and are not treated; history of the past: the lumbar vertebra has a history of 5 years, often lumbago, no history of hypertension and diabetes, no history of infection diseases such as tuberculosis, hepatitis B and the like, and no history of operation and trauma; history of marriage and childbirth: marrying with a healthy female at 26 years old, carrying 2 women, and performing physical examination on children; positive signs: the face color is dark, and tenderness is generated at the 19 th lumbar vertebra moxibustion point; the pulse condition: settling and delaying; tongue diagnosis: big, swollen and tender tongue with light color; and (3) diagnosis: kidney deficiency syndrome (kidney cold). The treatment method comprises the following steps: the principle of treating kidney cold dispelling and kidney qi nourishing is that the ointment formula of the invention is taken orally for one month and then rechecked. The symptoms of soreness and weakness of waist and knees of the patients are obviously improved during the reexamination, the patients are full of energy in the daytime, the appetite is increased, the sexual function is improved, and the like.

Physical examination: the face color is smooth, and the tenderness disappears at the 19 th lumbar vertebra moxibustion point; the pulse condition: regulating the pulse; tongue diagnosis: pale red, thin and white fur.

Case 2: name: jin x, male, age 39, Nei Mongolia red peak, no history of drug allergy. 2017.2.11 the physician needs to see the doctor in Mongolian medicine. The main complaints are: sexual function declined for more than 3 years. The current medical history: the patients have no obvious inducement for sexual life before 3 years, can not erect the yin channels, can not maintain sexual life after erection, and the like, and do not have symptoms in sexual life, and are not diagnosed and treated. History of the past: body health, no history of hypertension, diabetes, tuberculosis, hepatitis B and other infectious diseases, and no history of operation and trauma. History of marriage and childbirth: married with a healthy woman at age 22, born with 1 son and 1 woman, and examined the children. Positive signs: pale complexion and fat body; the pulse condition: settling and delaying;

tongue diagnosis: big, swollen and tender tongue with light color; and (3) diagnosis: kidney deficiency syndrome (kidney cold). The treatment method comprises the following steps: the formula of the invention is taken orally for one month, and then the health is exercised.

2017.3.12 the double diagnosis is made in Mongolian medicine. Patient complaint: after the medicine is taken for 1 week, the erection of the sexual life yin channel is improved, after the medicine is taken for 2 weeks, the sexual life is obviously improved, and at present, after the medicine is taken for 1 month, the sexual life is basically recovered to be normal. The face is ruddy and the body is fat; the pulse condition: regulating the pulse;

tongue diagnosis: thin and white moss; and (3) diagnosis: the pattern of kidney deficiency (kidney cold) is better. The treatment method comprises the following steps: continuously dispelling the kidney cold and nourishing the kidney qi are taken as the treatment principle, and the paste formula is orally taken for one month; discomfort and follow-up diagnosis.

Case 3: name: hoxx, male, 50 years old, inner mongolia sn allied dong wuqi flag, no history of drug allergy. 2015.09.03 the physician needs to see the doctor in Mongolian medicine. The main complaints are: premature ejaculation, soreness of waist and knees for 2 months; the current medical history: the patient has no obvious induction of sexual life premature ejaculation, fatigue, soreness and weakness of waist and knees, intermittent palpitation and insomnia before 2 months, and is diagnosed in our department at present, the appetite is good, and the stool is normal; history of the past: the history of chronic gastritis, stomachache and gastrectasia after intermittent meals is 5 years, the history of hypertension and diabetes, the history of infection diseases such as tuberculosis, hepatitis B and the like, and the history of operation and trauma are avoided; history of marriage and childbirth: marrying with a healthy female at the age of 20 years, breeding 2 women, and performing physical examination on children; positive signs: the surface color is black and dull; tongue diagnosis: pale tongue with white coating; urine diagnosis: light color, frequent urination, etc.; palpation: deep and thready pulse; and (3) diagnosis: kidney deficiency (kidney cold), stomach cold. The treatment method comprises the following steps: dispelling cold and nourishing kidney qi are treatment principles, and the ointment formula of the invention is rechecked after being orally taken for one month.

2017.4.16 the double diagnosis is made in Mongolian medicine. Patient complaint: after the medicine is taken for 1 week, the appetite is increased, the stomachache and gastrectasia times are reduced, the premature ejaculation and the waist difficulty are obviously improved after the medicine is taken for 2 weeks, the symptoms of the stomach illness and the waist difficulty are improved after the medicine is taken for 1 month, and the sexual life is recovered to be normal. The face is smooth and the body is thin; the pulse condition: the normal pulse; tongue diagnosis: thin and white moss; and (3) diagnosis: the pattern of kidney deficiency (kidney cold) and the improvement of stomach cold. The treatment method comprises the following steps: continuing to take the ointment of the invention orally for one month; discomfort and follow-up diagnosis.

Case 4: name: sxx, male, 48 years old, right flag of inner mongolian bailin, no history of herbal and mongolian allergies. 2015.04.18 the physician needs to see the doctor in Mongolian medicine. The main complaints are: impotence, premature ejaculation for more than 5 years; the current medical history: the patient has no obvious inducement to sexual hypofunction, sexual life premature ejaculation, fatigue, intermittent palpitation and insomnia before 5 years, and is diagnosed with appetite and chronic diarrhea (3-5 times a day, rare) in our family; history of the past: the health is good, the beer is drunk easily, the history of hypertension and diabetes, the history of infection diseases such as tuberculosis, hepatitis B and the like, and the history of operation and trauma are avoided; history of marriage and childbirth: marrying with a healthy female at age 22, carrying 1 woman, and performing physical examination on the woman; positive signs: the complexion is pale; tongue diagnosis: pale tongue with white coating; urine diagnosis: the color is light; palpation: sinking the pulse; and (3) diagnosis: kidney deficiency (kidney cold), liver cold. The treatment method comprises the following steps: dispelling cold and nourishing kidney qi are treatment principles, and the ointment formula of the invention is rechecked after being orally taken for one month.

2015.5.16 the double diagnosis is made in Mongolian medicine. Patient complaint: after 2 weeks of administration, the stool becomes thick and the sleep is improved, and after 1 month of administration, the palpitation, the diarrhea are improved, the libido is increased, and the sexual life premature ejaculation is slightly improved. White complexion and fat body; the pulse condition: sinking the pulse; tongue diagnosis: pale tongue with white coating; and (3) diagnosis: kidney deficiency (kidney cold), liver cold. The treatment method comprises the following steps: the cream formulation of the invention is taken orally continuously for one month and then reviewed.

2015.6.25 the double diagnosis is made in Mongolian medicine. Patient complaint: after 2 months of administration, the frequency of defecating is reduced (1-2 times per day), the defecating becomes thick, the color becomes normal, the sleep is improved, palpitation is avoided, and the sexual life is improved. The complexion is moist, and the body is fat; the pulse condition: the normal pulse; tongue diagnosis: pale tongue with thin and white coating; and (3) diagnosis: the pattern of kidney deficiency (kidney cold) is better. The treatment method comprises the following steps: the oral administration of the ointment formula of the invention is continued for one month, and the patient is not suitable for follow-up diagnosis.

Case 5: name: bexx, male, 52 years old, left flag of bailin, city of inner mongolian akang, without a history of herbal allergies. 2017.06.06 the physician needs to see the doctor in Mongolian medicine. The main complaints are: premature ejaculation, soreness and weakness of waist and knees for more than half a year; the current medical history: the patient has no obvious induction of sexual life premature ejaculation, fatigue, waist soreness and backache, night sweat and intermittent palpitation before half a year, and is diagnosed in our department at present, so that the patient can sleep, have appetite and have normal excrement; history of the past: rheumatic osteoarthropathy is caused by 5 years, perennial lumbocrural pain, no history of hypertension and diabetes, no history of infection such as tuberculosis, hepatitis B and the like, and no history of operation and trauma; history of marriage and childbirth: marrying with a healthy female at the age of 20 years, carrying 1 son, and carrying out physical examination on the son; positive signs: the surface color is black and dull; tongue diagnosis: thick tongue with yellow coating; urine diagnosis: the color is dark yellow; palpation: excessive pulse; and (3) diagnosis: kidney deficiency (kidney heat), joint-coordinating Niuhsu disease. The treatment method comprises the following steps: the treatment principle of nourishing kidney and harmonizing dryness with Niuhusu is that the ointment formula of the invention is taken orally for one month and then reviewed.

2017.7.10 the double diagnosis is made in Mongolian medicine. Patient complaint: symptoms of palpitation, waist distress and premature ejaculation are improved after the medicine is taken for 2 weeks, symptoms of waist distress, arthralgia and night sweat are improved after the medicine is taken for 1 month, and sexual life is obviously improved. The face is dark and the body is thin; the pulse condition: the normal pulse; tongue diagnosis: yellow moss; and (3) diagnosis: urine diagnosis: the color is light; kidney deficiency (kidney heat), joint-coordinating Niuhsu disease. The treatment method comprises the following steps: nourishing kidney, and coordinating dryness with Niuhusu as the treatment principle, the treatment method comprises the following steps: because joint synechiae disease is relatively stubborn, the ointment of the invention is continuously taken for 2 months to consolidate the treatment; discomfort and follow-up diagnosis.

Case 6: name: herxx, male, 36 years old, alucor qin, intraductal akange, no history of herbal allergies. 2018.08.14 the physician needs to see the doctor in Mongolian medicine. The main complaints are: premature ejaculation, soreness and weakness of waist and knees for 1 year, asthenia, night sweat and half-moon; the current medical history: the patient has no obvious induction of sexual life premature ejaculation and soreness and weakness of waist and knees before 1 year, and is diagnosis and treatment, the patient has weakness, night sweat and tiredness before drinking big wine before half a month and is occasionally worried, the patient can take the six-ingredient rehmannia pill (concentrated water pill), 8 pills and twice a day by himself, the symptom is not improved, the patient is diagnosed with the disease in our department at present, the appetite is poor after half a month, the defecation frequency is increased (4-6 times a day), and the stool is thin and small in amount; history of the past: health, no history of hypertension, diabetes, tuberculosis, hepatitis B and other infectious diseases, no history of operation and trauma; history of marriage and childbirth: marrying with a healthy female at 24 years old, carrying 2 children, and carrying out physical examination on children; positive signs: the face color is white and dull; tongue diagnosis: pale tongue with white coating; urine diagnosis: the color is light; palpation: sinking the pulse; and (3) diagnosis: kidney deficiency (kidney cold), and heart-induced heyi disease. The treatment method comprises the following steps: the treatment principles of dispelling cold, nourishing kidney fire and tonifying qi and blood are that the ointment formula of the invention is taken orally for one month and then rechecked.

2018.9.14 consult the patient by telephone. Patient complaint: after 2 weeks of administration, appetite is improved, debilitation and night sweat are obviously improved, stool becomes normal, waist sleepiness and night sweat symptoms are improved after 1 month of administration, stool is normal, sleep is normal, and sexual life is obviously improved. And (3) diagnosis: syndrome of kidney yang deficiency, improvement of heart-fire-heyi disease. Ordering: it is contraindicated for drinking, cold food and discomfort.

Case 7: name: maxx, male, 66 years old, intra-mongolian cattle, no history of herbal allergies. 2018.03.02 the physician needs to see the doctor in Mongolian medicine. The main complaints are: impotence for more than 2 years; the current medical history: the patients have no obvious inducement of sexual hypofunction, slow erection of yin essence, no erection and insomnia before 2 years, so the patients are diagnosed in our family at present, have appetite, normal stool and frequent nocturia (3-6 times at night); history of the past: health, no history of hypertension, diabetes, tuberculosis, hepatitis B and other infectious diseases, no history of operation and trauma; history of marriage and childbirth: marrying with a healthy female at the age of 24 years, breeding 2 women 1, and performing physical examination on the children; positive signs: wrinkles appear on the forehead, and the face is white; tongue diagnosis: pale tongue with white coating; urine diagnosis: the color is light; palpation: sinking the pulse; and (3) diagnosis: kidney deficiency syndrome (kidney cold). The treatment method comprises the following steps: the patient takes the ointment formula of the invention orally for one month and then rechecks according to the treatment principle of age, kidney qi loss, essence qi deficiency and long-term kidney qi nourishing.

2018.4.6 the double diagnosis is made in Mongolian medicine. Patient complaint: the nocturia is improved after the medicine is taken for 1 month, and the sexual life is improved. White complexion and fat body; the pulse condition: weak pulse; tongue diagnosis: pale tongue with white coating; and (3) diagnosis: kidney deficiency syndrome (kidney cold). The treatment method comprises the following steps: the compound of the invention is taken orally for 2 months and then is reviewed.

2018.6.10 the double diagnosis is made in Mongolian medicine. Patient complaint: after the medicine is taken for 2 months, the nocturia is reduced (1-2 times), the sexual life is obviously improved, and the spirit is refreshed. The face is ruddy and the body is fat; the pulse condition: the normal pulse; tongue diagnosis: pale tongue with thin and white coating; and (3) diagnosis: the pattern of kidney deficiency (kidney cold) is better. The treatment method comprises the following steps: according to the principle of reinforcing in summer and purging in winter, the ointment formula is continuously taken in winter, so that the patient is not suitable for diagnosis at any time.

Case 8: name: agaxx, male, 51 years old, alucor qin, intraductal erythropeak, no history of drug allergy. 2018.10.10 the physician needs to see the doctor in Mongolian medicine. The main complaints are: hyposexuality, intermittent cough, phlegm cough, asthma, and suffocating for more than 4 years; the current medical history: the patient has no obvious reason for hyposexuality, no interest in sexual life, intermittent cough, white phlegm cough and dyspnea, and is diagnosed in our department at present, so that the patient has a moderate appetite and normal defecation; history of the past: the bronchial allergic asthma is treated by Mongolian medicines and western medicines (the name and the amount of the medicines are not detailed) which are taken intermittently for 8 years, and the treatment has no history of hypertension and diabetes, no history of infectious diseases such as tuberculosis, hepatitis B and the like, and no history of operation and trauma; history of marriage and childbirth: marrying a healthy female at 26 years old, carrying 1 son, and carrying out physical examination on the son; positive signs: the face color is white and dull; tongue diagnosis: pale tongue with white coating; urine diagnosis: the color is light; palpation: deep and thready pulse; and (3) diagnosis: kidney deficiency (kidney cold), lung heyi disease. The treatment method comprises the following steps: the treatment principles of dispelling cold, nourishing kidney qi, warming and tonifying lung and relieving asthma are that the ointment formula of the invention is taken orally for one month and then rechecked.

2018.11.14 the double diagnosis is made in Mongolian medicine. Patient complaint: after the medicine is taken for 1 week, the appetite is increased, the symptoms of cough, expectoration and asthma are obviously improved, and the sexual life is improved. The face is bright and the body is fat; the pulse condition: weak pulse; tongue diagnosis: thin and white moss; and (3) diagnosis: the pattern of kidney deficiency (kidney cold) and improvement of lung He Yi disease. The treatment method comprises the following steps: continuously taking the ointment of the invention for 2 months; discomfort and follow-up diagnosis.

Case 9: name: xxx, male, 68 year old, meng xingjiang alliance, 361699, Teqi.

2018.12.18 the physician needs to see the doctor in Mongolian medicine. The main complaints are: the cold is good, the cough and the asthma are suffocated for more than 2 years; the current medical history: patients become cold with winter weather, cough, white phlegm and suffocating, see local hospitals for tracheitis, give roxithromycin capsules and montelukast sodium tablets, are confident and the like (dosage and use are unknown) and see our family at present. Poor sleep, appetite, normal stool and urine; history of the past: the health is good, no smoke or alcohol is drunk, no history of hypertension and diabetes, no history of infection such as tuberculosis, hepatitis B and the like, and no history of operation and trauma; history of marriage and childbirth: marrying with a healthy female at age 22, breeding 2 women, and performing physical examination of children; positive signs: the color of the face is dark; tongue diagnosis: pale tongue with white coating; urine diagnosis: the color is light; palpation: weak pulse; and (3) diagnosis: lung deficiency (cold). The treatment method comprises the following steps: the principle of dispelling cold and benefiting lung is that the ointment formula of the invention is taken orally for one month and then is reviewed.

2019.1.16 the double diagnosis is made in Mongolian medicine. Patient complaint: after taking the medicine for one treatment course, the sleep is improved, the cough and asthma are improved, the appetite is increased, and the physical strength is recovered. The color of the face is ruddy; the pulse condition: regulating the pulse; and (3) diagnosis: the lung-deficiency syndrome is better. The treatment method comprises the following steps: the oral administration of the cream formulation of the present invention was continued for one month.

Case 10: name: qiao X, male, age 52, province Hebei.

2018.06.14 the physician needs to see the doctor in Mongolian medicine. The main complaints are: abdominal distension and abdominal discomfort for more than 6 years; the current medical history: patients are diagnosed in local hospitals for abdominal discomfort, abdominal distension, anorexia and the like caused by fatigue, improper diet and other discomfort factors 6 years ago, liver cirrhosis and chronic hepatitis B are diagnosed, oral entecavir dispersible tablets, lactobacillus tablets, omeprazole capsules, turtle shell liver softening tablets and the like (dosage is unknown) are given, the illness state is good and bad, and the patients are diagnosed in our department at present, and the patients have emaciation, sleep quality, poor appetite, clear stool, slight yellow urine and appropriate dosage; history of the past: the health is strong, the history of hypertension, diabetes and tuberculosis does not exist, the history of hepatitis B is found for more than 20 years through physical examination, and the history of operation and trauma does not exist; history of marriage and childbirth: marrying with a healthy female at age 22, bearing 1 son, and carrying out physical examination of the son; positive signs: the surface color is black and dull; tongue diagnosis: thick tongue with yellow coating; urine diagnosis: the color is dark yellow; palpation: deficient pulse; and (3) diagnosis: liver deficiency syndrome (liver cold). The treatment method comprises the following steps: the basic treatment principles of dispelling liver cold, clearing turbidity and nourishing liver are that the ointment formula of the invention is taken orally for one month and then rechecked.

2018.7.15 the double diagnosis is made in Mongolian medicine. After the medicine is taken for 1 month, the appetite is increased, the abdominal distension, the abdominal discomfort and the hypodynamia are improved, and the spirit is obviously improved. The complexion is improved, and the body is thin; the pulse condition: weak pulse; tongue diagnosis: yellow moss; and (3) diagnosis: urine diagnosis: the color is light; syndrome of liver deficiency. The treatment method comprises the following steps: the treatment principle of continuously dispelling cold and nourishing liver is that the treatment method comprises the following steps: the paste formula of the invention is continuously taken orally for 2 months to consolidate the treatment; discomfort and follow-up diagnosis.

Case 11: name: herxx, female, 36 years old, alucor qin, intraductal akange, no history of herbal allergies.

2018.1.10 the physician needs to see the doctor in Mongolian medicine. The main complaints are: dysmenorrhea, menoxenia 10 more years; the current medical history: the patients have irregular menstruation after being cooled before 10 years, the menstrual period is shortened, generally 20 days are menstrual, the menstrual period lasts for 5-9 days, the premenstrual period is accompanied by abdominal pain and lumbago, the effects of taking black-bone chicken and white phoenix pills, golden lack kidney qi pills and the like are poor, and the patients are diagnosed in the department today; history of the past: health, no history of hypertension, diabetes, tuberculosis, hepatitis B and other infectious diseases, no history of operation and trauma; history of marriage and childbirth: marrying with a healthy female at 24 years old, carrying 1 son, and carrying out physical examination on the son; positive signs: the surface color is grey and dull; tongue diagnosis: pale tongue with thin and yellow coating; urine diagnosis: the color is light; palpation: sinking the pulse; and (3) diagnosis: pattern of uterus cold. The treatment method comprises the following steps: the treatment principles of dispelling cold, nourishing kidney fire and tonifying qi and blood are that the ointment formula of the invention is rechecked after 2 months of oral administration, is forbidden to produce cold food and is discomfortable for follow-up diagnosis.

2018.3.12 the patient is consulted by telephone on day. Patient complaint: after the medicine is taken for two months, hands and feet are heated, the physical strength is obviously improved, and the symptoms of dysmenorrheal are improved. And (3) diagnosis: the pattern of cold in the uterus is better.

The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (1)

1. A Mongolian medicine for treating kidney-yang deficiency is characterized by comprising the following steps:

s1, weighing 12.5g of northern glauberite, 50g of conic gymnadenia rhizome, 50g of pomegranate, 50g of myrobalan, 50g of white raisin, 25g of white kowter, 25g of areca nut, 25g of trogopterus dung, 25g of crab, 25g of black borneol, 20g of long pepper, 20g of rhizoma polygonati, 20g of radix asparagi, 15g of radix polygonati officinalis, 15g of cinnamon, 15g of dried ginger, 15g of piper nigrum, 15g of tribulus terrestris, 15g of nutmeg, 15g of snap white, 15g of malva seed, 15g of white pepper, 10g of caoguo, 10g of fructus choerospondiatis, 5g of sal ammoniac, 10g of hot pepper, 5g of flos caryophylli and 10g of sword bean, and adding water to soak for 12 hours;

s2, decocting the soaked medicines for three times, and mixing and containing liquid medicines decocted for three times;

s3, standing and precipitating the decocted liquid medicine, and filtering by using gauze;

s4, decocting the filtered liquid medicine to be thick by three stages of strong fire, medium fire and slow fire;

s5, adding 5ml of sesame oil, 12.5g of north gypsum rubrum, 15g of agilawood, 15g of dalbergia wood, 5g of sal ammoniac, 5g of asafetida, 5g of notopterygium, 150g of white sugar or rock sugar, 250g of brown sugar, 50g of honey and 100ml of milk wine into the thick paste liquid medicine, and collecting the paste with small fire;

and S6, placing the prepared plaster into a sealed container, and storing in a refrigerator.