CN109453317A - A kind of anaesthetic and its preparation process for strengthening by means of tonics - Google Patents

A kind of anaesthetic and its preparation process for strengthening by means of tonics Download PDF

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Publication number
CN109453317A
CN109453317A CN201811650301.3A CN201811650301A CN109453317A CN 109453317 A CN109453317 A CN 109453317A CN 201811650301 A CN201811650301 A CN 201811650301A CN 109453317 A CN109453317 A CN 109453317A
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parts
water
anaesthetic
alkali ion
spare
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不公告发明人
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AFFILIATED HOSPITAL OF INNER MONGOLIA UNIVERSITY FOR NATIONALITIES
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016Disaccharides, e.g. lactose, lactulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20Milk; Whey; Colostrum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/24Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8965Asparagus, e.g. garden asparagus or asparagus fern
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The present invention relates to a kind of drugs and preparation method thereof, i.e. a kind of anaesthetic and its preparation process for strengthening by means of tonics, it is characterised in that: this drug is made of according to a certain weight ratio 15 taste ingredients such as honey, butter, milk, rock sugar, brown sugar, radix polygonati officinalis, radices trichosanthis, lucid asparagus, rhizoma polygonati, cortex cinnamomi (removing rough bark), Concretio Silicea Bambusae, rhizoma gymnadeniae, natural salt, excrementum pteropi, HALITUM PURPUREUMs.The preparation process of this drug is: by part material medicine through acid electrolyzed functional water sterilizing, then being decocted with alkali ion water, is eventually adding remaining ingredient, oily ball is made.The beneficial effect is that: it is theoretical according to Mongolian medicine Six-element effect, in conjunction with anaesthetic pharmacological property, research and develop it is a kind of with healthcare, enhancing physique, tonifying kidney and prolonging life effect health medicine prescription, and combine traditional handicraft with modern technologies, obtain a kind of easy to operate, unique pharmaceutical preparation of method.

Description

A kind of anaesthetic and its preparation process for strengthening by means of tonics
Technical field
The present invention relates to a kind of drug and preparation method thereof, i.e., a kind of anaesthetic and its preparation process for strengthening by means of tonics.
Background technique
With the arrival of China's aging society, health, health care, the quality of life of the elderly etc. are by more next The highest attention of more people.In general, with advancing age, many elderlys are it is possible that physiological function and metabolism function Degeneration or damage that can be different degrees of, bring serious harm to health.In addition, the elderly especially man at an advanced age is to life The demands such as treatment, rehabilitation nursing, health care rapidly increase, and bring certain economic pressures to personal and family.It can be said that old Year people's Physical Health Status directly affects the harmony of the quality of life in their old ages and the stabilization of family and society.In addition, For present more and more office workers since work, life stress are big, spirit is overstretched, along with diet is irregular, sleeps not The reasons such as foot can not reach the standard of health, show as tired nothing although causing them specific disease does not occur Power, joint pain, dizzy headache, palpitaition is uncomfortable in chest, sleep disordered, vigor reductions, immunity degradation, function and adaptability decline Equal subhealth symptoms.
It is flooded with the health care medicinal of various anti-aging classes, extra-nutrition class, health class, the class that is guaranteed to cure all diseases currently on the market Product make the confusion of health medicine market grow thickly.The reason of causing this phenomenon although have industry threshold is low, government regulation is difficult, lack The factors such as knowledge on drug abuse, but also illustrate that quality is high, effect is good, low-cost health care product and drug are relatively deficient.It is domestic regular Health medicine mainly based on traditional Chinese medicine health care prescription, and important composition portion of the Mongolia Medicine as China's traditional medicine Point, there is unique theoretical, recipe and dosage form in terms of health care, but due to a lack of modern pharmacology, pharmacodynamic study, promote Application difficult.Under the high-incidence background of aging society and inferior health, it is badly in need of under Mongolian medicine's theoretical direction and anaesthetic tradition prescription On the basis of, exploitation is used for the anaesthetic novel composing prescription of health care, and further expansion people select the range of high quality health medicine, Meet people to build up health, regulative mechanism, ensure healthy medication demand.
Summary of the invention
The purpose of the present invention is developing, a kind of quality is high, effect is good, the low-cost anaesthetic prescription for strengthening by means of tonics.
It is a further object of the present invention to provide a kind of preparation processes of anaesthetic for strengthening by means of tonics.
Above-mentioned purpose is realized by the following technical solutions: providing a kind of anaesthetic for strengthening by means of tonics, it is characterised in that: The raw material medicaments in part by weight proportion of this drug is 4800-7200 parts of honey, 4000-6000 parts of butter, milk 2000- 3000 parts, 800-1200 parts of rock sugar, 720-1080 parts of brown sugar, 80-120 parts of excrementum pteropi, 72-108 parts of rhizoma gymnadeniae, radix polygonati officinalis 40-60 parts, 40-60 parts of radices trichosanthis, 40-60 parts of lucid asparagus, 40-60 parts of rhizoma polygonati, 8-12 parts of cortex cinnamomi (removing rough bark), nandina Yellow 8-12 parts, 8-12 parts of natural salt, 8-12 parts of HALITUM PURPUREUM.
The preferred embodiment of above-mentioned formula material medicine by weight ratio is: 6000 parts of honey, 5000 parts of butter, milk 2500 Part, 1000 parts of rock sugar, 900 parts of brown sugar, 100 parts of excrementum pteropi, 90 parts of rhizoma gymnadeniae, 50 parts of radix polygonati officinalis, 50 parts of radices trichosanthis, lucid asparagus 50 Part, 50 parts of rhizoma polygonati, 10 parts of cortex cinnamomi (removing rough bark), 10 parts of Concretio Silicea Bambusae, 10 parts of natural salt, 10 parts of HALITUM PURPUREUM.
The preparation process of above-mentioned anaesthetic is: purified tap water is fitted into ionic water generator, by positive and negative electrode, Alkali ion water and acid electrolyzed functional water are respectively obtained under the action of electric field, it is spare, by excrementum pteropi, rhizoma gymnadeniae, radix polygonati officinalis, smallpox Powder, lucid asparagus, rhizoma polygonati, cortex cinnamomi (removing rough bark), Concretio Silicea Bambusae mixing, Plus acidic ionized water impregnate 5min, filter out acid electrolyzed functional water, It is dried, crushed into coarse powder, adds alkali ion water, alkali ion water water there was not 1-2cm of medicinal material, continues after impregnating 30min, uses It uses mild fire after boiling with strong fire instead, keeps slightly boiled, after decocting 20min, filtering obtains extracting solution, and the dregs of a decoction decoct 2 with alkali ion water again It is secondary, merge No. 3 extracting solutions, it is spare, natural salt, HALITUM PURPUREUM are mixed, crushes, sieves with 100 mesh sieve, it is spare, by butter, milk, bee Honey, brown sugar, rock sugar, natural salt, HALITUM PURPUREUM are added in extracting solution, are concentrated into no moisture, when being presented glossy damp, red-black transparent, Be made oily ball to get.
4800-7200 parts of the honey, 4000-6000 parts of butter, 2000-3000 parts of milk, rock sugar 800-1200 Part, 720-1080 parts of brown sugar, 80-120 parts of excrementum pteropi, 72-108 parts of rhizoma gymnadeniae, 40-60 parts of radix polygonati officinalis, radices trichosanthis 40-60 Part, 40-60 parts of lucid asparagus, 40-60 parts of rhizoma polygonati, 8-12 parts of cortex cinnamomi (removing rough bark), 8-12 parts of Concretio Silicea Bambusae, natural salt 8-12 120-180 parts of myrobalan, 120-180 parts of Fructus meliae toosendan, 120-180 parts of pomegranate, gypsum rubrum is added in part, 8-12 parts of HALITUM PURPUREUM 120-180 parts of (system), 52-78 parts of Bi Bi, 60-90 parts of cape jasmine, 44-66 parts of pepper, 40-60 parts of puncture vine (system), oriental wormwood 40-60 parts, 40-60 parts of cacumen biotae, 40-60 parts of Chinese ephedra, 40-60 parts of rhododendron leaves, 28-42 parts of Amomum cardamomum, galangal 24- 36 parts, 20-30 parts of Radix Ophiopogonis, 20-30 parts of safflower, 12-18 parts of nutmeg, 8-12 parts of cloves, 8-12 parts of tsaoko.
The preparation process of above-mentioned anaesthetic is: purified tap water is fitted into ionic water generator, by positive and negative electrode, Alkali ion water and acid electrolyzed functional water are respectively obtained under the action of electric field, it is spare, by excrementum pteropi, rhizoma gymnadeniae, radix polygonati officinalis, smallpox Powder, lucid asparagus, rhizoma polygonati, cortex cinnamomi (removing rough bark), Concretio Silicea Bambusae, myrobalan, Fructus meliae toosendan, cape jasmine, puncture vine (system), pomegranate, galangal, wheat Winter, Amomum cardamomum, Bi Bi, oriental wormwood, pepper, cacumen biotae, Chinese ephedra, rhododendron leaves, nutmeg, safflower, cloves, tsaoko mixing, it is Plus acidic Ionized water impregnates 5min, filters out acid electrolyzed functional water, be dried, crushed into coarse powder, add alkali ion water, alkali ion water water does not have 1-2cm of medicinal material is crossed, continues after impregnating 30min, uses mild fire after boiled with high heat instead, keeps slightly boiled, after decocting 20min, filtering, Extracting solution is obtained, the dregs of a decoction are decocted 2 times with alkali ion water again, merge No. 3 extracting solutions, and it is spare, by natural salt, HALITUM PURPUREUM, gypsum rubrum (system) mixing, crushes, sieves with 100 mesh sieve, spare, by butter, milk, honey, brown sugar, rock sugar, natural salt, HALITUM PURPUREUM, gypsum rubrum (system) is added in extracting solution, is concentrated into no moisture, present glossy pool, it is red-black transparent when, be made oily ball to get.
The beneficial effects of the present invention are: theoretical according to Mongolian medicine Six-element effect, in conjunction with anaesthetic pharmacological property, researching and developing one kind has The health medicine prescription that healthcare, enhancing physique, tonifying kidney and prolonging life act on, and traditional handicraft is combined with modern technologies, it obtains Obtain a kind of easy to operate, unique pharmaceutical preparation of method.
Specific embodiment
The first embodiment: purified tap water is fitted into ionic water generator, by positive and negative electrode, in electric field Alkali ion water and acid electrolyzed functional water are respectively obtained under effect, it is spare.80-120 parts of excrementum pteropi, rhizoma gymnadeniae are taken by weight 72-108 parts, 40-60 parts of radix polygonati officinalis, 40-60 parts of radices trichosanthis, 40-60 parts of lucid asparagus, 40-60 parts of rhizoma polygonati, cortex cinnamomi (go thick Skin) 8-12 parts, 8-12 parts of Concretio Silicea Bambusae mixing, Plus acidic ionized water impregnates 5min, filters out acid electrolyzed functional water, be dried, crushed into Coarse powder adds alkali ion water, and alkali ion water water there was not 1-2cm of medicinal material, continues after impregnating 30min, changes after boiled with high heat With mild fire, keep slightly boiled, after decocting 20min, filtering obtains extracting solution, and the dregs of a decoction are decocted 2 times with alkali ion water again, merges 3 times and mentions Liquid is taken, it is spare.8-12 parts of natural salt, 8-12 parts of HALITUM PURPUREUM mixing are taken by weight, are crushed, are sieved with 100 mesh sieve, it is spare, by weight Amount part takes 4800-7200 parts of honey, 4000-6000 parts of butter, 2000-3000 parts of milk, 800-1200 parts of rock sugar, brown sugar 720-1080 parts, 8-12 parts of natural salt, 8-12 parts of HALITUM PURPUREUM be added in extracting solution, be concentrated into no moisture, present glossy Pool, it is red-black transparent when, be made oily ball to get.
Above-mentioned raw materials medicine prescription and processing method can in the following manner preferably: 100 parts of excrementum pteropi preferred by weight, palm 90 parts of ginseng, 50 parts of radix polygonati officinalis, 50 parts of radices trichosanthis, 50 parts of lucid asparagus, 50 parts of rhizoma polygonati, 10 parts of cortex cinnamomi (removing rough bark), 10 parts of Concretio Silicea Bambusae it is mixed It closes, Plus acidic ionized water, impregnates 5min, filter out acid electrolyzed functional water, be dried, crushed into coarse powder, add alkali ion water, alkali ion Water water there was not 1-2cm of medicinal material, continues after impregnating 30min, uses mild fire after boiled with high heat instead, keeps slightly boiled, decocts 20min Afterwards, it filters, obtains extracting solution, the dregs of a decoction are decocted 2 times with alkali ion water again, merge No. 3 extracting solutions, spare, light preferred by weight 10 parts of bright salt, 10 parts of HALITUM PURPUREUM mixing, crush, sieve with 100 mesh sieve, it is spare, take by weight 6000 parts of honey, 5000 parts of butter, 2500 parts of milk, 1000 parts of rock sugar, 900 parts of brown sugar, 10 parts of natural salt, 10 parts of HALITUM PURPUREUM be added in extracting solution, be concentrated into nothing Moisture, present glossy pool, it is red-black transparent when, be made oily ball to get.Adult is every to take 6g, 2 times a day.
One, anaesthetic prescription theory is analyzed:
Plurality of raw materials medicine is often divided into sweet, sour, salty, bitter, pungent, puckery six kinds of tastes by anaesthetic, it is believed that different flavour of a drug have different Therapeutic effect, and identical flavour of a drug, there is close or identical effect.Wherein clearing heat and detoxicating, the regulation of qi and blood of sugariness energy is nourished strong Body prolongs life, and adds smart mends marrow, and synthetism is cured the wound, and improves eyesight, hearing etc., and for deficiency of vital energy and blood, consumptive disease internal injury etc., drug has Radix Glycyrrhizae, radix polygonati officinalis, rhizoma polygonati, fatty oil, honey, carbohydrate, milk etc.;Tart flavour can reconcile stomach fire, decomposed food, and appetite-stimulating and indigestion-relieving etc. is used for Stomach fire is weak, indigestion, loss of appetite, abdominal distension uncomfortable in chest etc., and drug has pomegranate, persimmon, wild jujube, sea-buckthorn etc.;Saline taste can make body Body is solid, dredges spasmolysis, controls occlusion obstruction, adjusts sun, and appetizing is weak, swollen for tetany, constipation, abdominal distension, stasis, digestion The diseases such as tumor, drug have green salt, red salt, natural salt, sal ammoniac, saltcake, nitre etc.;Bitter taste can disappear, and heat drop is fiery, and removing toxic substances is calm, detumescence, Sharp larynx, eliminating dampness, preventing or arresting vomiting etc., for warm blood pyreticosis, poisoning, pestilence, acute mastitis, abscess of throat, uncommon drawing disease, polydipsia, and headache Dizziness, Nausea and vomiting, dysphoria etc., drug have the coptis, Hu Lian, Cortex Phellodendri, radix scutellariae, cape jasmine, Chinese violet, Fructus Forsythiae, sweet wormwood etc.;It is pungent Taste can dispel conspicuous according to dispersing wind and cold, and strongly fragrant, promotion ideas-straightening is opened in stomach invigorating, dampness removing and diarrhea-relieving, treatment trauma, appetite-stimulating and indigestion-relieving etc., weak for stomach fire, disappear Change bad, loss of appetite, incoordination between the spleen and the stomach, vomiting hiccup, fullness and oppression of chest and abdomen, edema water, cold dysentery abdominal pain, wind-cold-dampness arthralgia, waist and leg ache Etc. diseases, drug have rhizoma zingiberis, pepper, capsicum, asafoetide, garlic etc.;Astringent taste can restrain sore sore, improve the colour of skin, eliminating dampness, disappear rouge, only It rushes down, removing heat from blood, fall fire etc., has myrobalan, Fructus meliae toosendan, acorn nut etc. for diseases, drugs such as sore, diarrhea, pyogenic infections, blood-head.
Mongolian medicine thinks to decompose after compatibility of drugs is taken by digestion, its original flavour of a drug can be changed, effect also changes correspondingly. Six-element converts substantially in vivo 3 kinds, referred to as " new three taste ".It is sugariness after the i.e. sweet and stronger conversion of saline taste, tart flavour is stronger Conversion after be still tart flavour, be bitter taste after the conversion of bitter, pungent, puckery three tastes.
The anaesthetic principles of formulating prescriptions in the present embodiment are to take into account single anaesthetic according to anaesthetic Six-element and " new three taste " effect theory Pharmacological property and removing toxic substances, abirritation, and combine monarch, minister, help, make to carry out prescription and compatibility, on the basis of traditional mongolian medicine prescription, It is obtained by a large amount of pharmacological evaluation and clinical trial.The present embodiment anaesthetic prescription element is sugariness or saline taste medicinal material, in people It is sugariness efficiency after conversion after being digested and decomposed in body alimentary canal, has to human body and nourish strong kidney, keep fit and healthy, improve Voxel prolongs life, and improves eyesight, hearing and other effects.
Two, anaesthetic prescription element is analyzed:
The reprocessing product after white sugar is made for gramineae plant sugarcane Saccharum sinensis Roxb in rock sugar.This taste It is sweet, there is tonifying middle-Jiao and Qi, stomach function regulating moistening lung is relieving cough and reducing sputum, dispel it is tired quench one's thirst, turbid, nourishing Yin and promoting production of body fluid, hidroschesis removing toxic substances and other effects drop in heat-clearing.
Honey is Hymenoptera honeybee kind insect apis cerana Apis cerana Fabricius or apis mellifera Linnaeus Apis The honey that mellifera L. is made.This product is sweet in flavor, has the Ba Dagan that dispels, ease constipation removing toxic substances, and dry purulence and yellow water, harmonizing the spleen and stomach increase The effect of strong nutrition.
Cortex cinnamomi is the dry bark of lauraceae plant cortex cinnamomi Cinnamomun cassia Presl.This product is sweet in flavor, pungent, micro- It is salty, it is slightly poisonous, have dispelling cold it is conspicuous according to, adjust stomach fire, antidiarrheal, the effect of holding back purulence.
Excrementum pteropi is the drying of flying squirrel section animal trogopterus xanthipes Milne-Edwards Trogopterus xanthipes Milne-Edwards Excrement.It is this product bitter, micro- salty.With heat-clearing, voxel is improved, the effect of analgesic, diuresis, stagnation resolvation.
Concretio Silicea Bambusae is gramineae plant bambusa texlitis Bambusa toxtilis Mc Clure etc. because by parasitic tabasheer bee After stinging hole, the juice stored up between ring, through block made of dry condensation.This product is sweet in flavor, have heat-clearing, cough-relieving, slit phlegm, Cool heart arresting convulsion.
Radix polygonati officinalis, for the dry rhizome of liliaceous plant radix polygonati officinalis Polygonatum Odratum(Mill.) Druce.This taste It is sweet, there is strengthening by means of tonics, dry yellow water, kidney of dispelling is cold, and suppression is conspicuous according to the effect of adjusting stomach fire.
Rhizoma polygonati is liliaceous plant polygonatum kingianurn Polygonatum Kingianum Goll. et Hemsl., more rhizoma polygonatis Polygonatum sibiricum Delar. Ex Pedoute's and flower rhizoma polygonati Polygonatum cyrtonema Hua. is dry Dry rhizome.This product is sweet in flavor, puckery, bitter, has Yang nourishing-strengthening, adjusts stomach fire, and appetizing, dispel Ba Dagan, restrains fester, the function for yellow water of dispelling Effect.
Lucid asparagus, for the dry of liliaceae plant asparagus Asparagus cochinchinen-sisi(Lour.) Merr. Dry root tuber.This product is sweet in flavor, puckery, bitter, has nourishing, controls spermatorrhea, removes yellow water, suppression it is conspicuous according to, clear latent pyrexia and it is old hot the effect of.
Radices trichosanthis is Curcurbitaceae Trichosanthes snakegourd Trichosanthes Kirilowii Maxim., or Japanese Chinese juniper The dry root of building Trichosanthes Japonica Regel..This product is sweet in flavor, has Yang nourishing-strengthening, and kidney of dispelling is cold, removes yellow water, The effect of broken stone ruffian.
Rhizoma gymnadeniae is the dry tuber of orchid rhizoma gymnadeniae Gymnadenia conopsea (L.) R. Br..This product It is sweet in flavor, the effect of there are benefiting male body essence and invigorating sex functions, control spermatorrhea.
Natural salt is Natural Food salt crystal, and main component is sodium chloride.This product is sweet in flavor, salty, has conditioning stomach fire, disappears Food, the Ba Dagan that dispels are conspicuous according to the effect of improving eyesight.
HALITUM PURPUREUM, the lump shaped crystalline body of purple halite Halite Violaceous, main component is sodium chloride.This taste It is salty, pungent, there is the effect of inhibition Ba Dagan, He Yi, tune stomach fire, soft stool, analgesic.
Milk, butter, brown sugar are the object of sweetness, have strengthening by means of tonics, promote longevity, and stomach invigorating salubrity improves constitution, helps Digestion promotes essence and waste matter to decompose, and soft skin improves sleep and other effects, and the figuration substance as anaesthetic finish dosage form.
Three, industrial analysis:
Ionized water is one kind of function water, is the general designation of alkali ion water and acid electrolyzed functional water.Tap water is through ionic water generator After electrolysis, cathode chamber generates alkali ion water, and anode chamber generates acid electrolyzed functional water.
For the pH of alkali ion water generally 7.5-9.5 or so, it can neutralize intracorporal acidic metabolite, be conducive to balance Due to the lactic acid of overworked generation in human body, constitution acidification is prevented, a variety of disease risks are eliminated.Alkali ion water contains rich Rich minerals and microelement, and being easily absorbed by the human body in ionic state, can effectively supplement trace minerals and microelement, Be conducive to human health.Adhere to drinking alkali ion water for a long time, is a kind of cheap, effective health care and the method cured the disease.Alkalinity Ionized water is different from the micel of light water, and common water clusters have 9-13 hydrones, and alkali ion water clusters only have 5-6 hydrones, the subset of alkali ion water have that penetration is strong, solubility is high, movement velocity is fast, are more advantageous to medicine Object effective component leaches.
The pH of acid electrolyzed functional water is between 5-6.5.Acid electrolyzed functional water can effectively remove all kinds of bacteriums, virus.Acid ion Water one touches bacterium, just can capture the electronics of bacterium, changes the balance inside and outside its cell membrane, destroys cell membrane, plays sterilization Effect, acid electrolyzed functional water can effectively remove such as staphylococcus 209P, Escherichia coli W3110 and salmonella UTB29, sterilize Bactericidal effect is clearly.Acid electrolyzed functional water as a kind of completely new disinfection sanitizer, have generate it is easy, easy to use, kill The advantages that bacterium power is strong, sterilizing time is short and noresidue.
First by the of short duration immersion of the medicinal acid electrolyzed functional water of raw material in the present embodiment, then sterilizing uses alkali ion decocting It boils, alkali ion water is more advantageous to effective ingredient leaching, and minerals in alkali ion water and microelement are in moisture content It is stayed in drug after being evaporated, increases the content of drug mineral and microelement.
Four, process test research: purified water, which is decocted, decocts comparative experiments with ionized water:
Take excrementum pteropi 100g, rhizoma gymnadeniae 90g, radix polygonati officinalis 50g, radices trichosanthis 50g, lucid asparagus 50g, rhizoma polygonati 50g, cortex cinnamomi (removing rough bark) 10g, Concretio Silicea Bambusae 10g mixing, are ground into coarse powder, add purified water, and water there was not 1-2cm of medicinal material, after impregnating 30min, baked wheaten cake of useing force It uses mild fire after opening instead, keeps slightly boiled, after decocting 20min, filtering obtains extracting solution, and the dregs of a decoction are decocted 2 times with purified water again, merges 3 times Extracting solution obtains solution A, measures colony counts, minerals and the active constituent content of solution A respectively.Measurement result is shown in Table 1.
Excrementum pteropi 100g, rhizoma gymnadeniae 90g, radix polygonati officinalis 50g, radices trichosanthis 50g, lucid asparagus 50g, rhizoma polygonati 50g, cortex cinnamomi is taken (to go thick Skin) 10g, Concretio Silicea Bambusae 10g mixing, Plus acidic ionized water, impregnate 5min, filter out acid electrolyzed functional water, be dried, crushed into coarse powder, add Alkali ion water, alkali ion water water there were not 1-2cm of medicinal material, continued after impregnating 30min, used mild fire instead after boiled with high heat, Keep slightly boiled, after decocting 20min, filtering obtains extracting solution, and the dregs of a decoction are decocted 2 times with alkali ion water again, merge No. 3 extracting solutions, obtain Solution B measures colony counts, minerals and the active constituent content of solution B respectively.Measurement result is shown in Table 1.
It can be seen that the content of effective component protocatechuic acid and cinnaldehydrum in solution B from 1 measurement result of table and be all remarkably higher than solution Content in A;The content of solution B mineral Ca and Mg are all remarkably higher than the content in solution A;In solution B staphylococcus and The quantity of Escherichia coli is substantially less than the quantity in solution A.Illustrate the medicinal ionized water sterilizing of raw material, immersion, decoct effect Fruit is better than purified water.
Five, toxicological experiment:
The preparation of anaesthetic: excrementum pteropi 100g, rhizoma gymnadeniae 90g, radix polygonati officinalis 50g, radices trichosanthis 50g, lucid asparagus 50g, rhizoma polygonati 50g, meat are taken 10 parts of osmanthus (removing rough bark) g, Concretio Silicea Bambusae 10g mixing, Plus acidic ionized water impregnate 5min, filter out acid electrolyzed functional water, dry, pulverize At coarse powder, add alkali ion water, alkali ion water water there was not 1-2cm of medicinal material, continued after impregnating 30min, after boiled with high heat It uses mild fire instead, keeps slightly boiled, after decocting 20min, filtering obtains extracting solution, and the dregs of a decoction are decocted 2 times with alkali ion water again, merges 3 times Extracting solution, it is spare, it takes natural salt 10g, HALITUM PURPUREUM 10g to mix, crushes, sieve with 100 mesh sieve, it is spare, take honey 6000g, butter 5000g, milk 2500g, rock sugar 1000g, brown sugar 900g, natural salt 10g, HALITUM PURPUREUM 10g are added in extracting solution, are concentrated into nothing Moisture, present glossy pool, it is red-black transparent when, be made oily ball to get.
Mouse Acute Toxicity experiment: concentration and administered volume by drug are limited, the mouse median lethal dose of anaesthetic (LD50) can not measure, therefore only carried out the experiment of mouse maximal tolerance dose.Specific experiment is as follows: taking experiment grade mouse 40, body Weight (20 ± 2) g, half male and half female are randomly divided into blank group and observation group, and every group 20, half male and half female.After being deprived of food but not water 12h, The every 10g mouse of the mouse of observation group gives 0.3g anaesthetic, is equivalent to 300 times of adult clinical equivalent dosage, stomach-filling on the one 2 times, Every minor tick 6h.The mouse of blank group gives same dose of distilled water, stomach-filling on the one 2 times, every minor tick 6h.It is continuous after administration Observe 6h, from administration second day play administration after the 14th day, daily morning and afternoon respectively observe and record an animal toxic reaction and Death condition, and weigh within the 7th day and the 14th day after administration, record mouse weight growth pattern;Cervical dislocation is put to death within 14th day All mouse are dissected rapidly, visually observe each tissue, internal organs, have obvious lesion Zhe Qu linked groups to do pathological examination.Mouse Acute toxicity testing result: after anaesthetic administration, observation group mouse is shown normally.All mouse of observation group the 7th day and 14 days Body weight increase is normal, is dissected and observed after execution, each tissue, organ Non Apparent Abnormality.Prompt the medicine free of toxic effects.
Rat long term toxicity test: by rat Animal Lab. breeding observing 1 week, including appearance sign, row before experiment For activity, glandular secretion, breathing, fecal character, appetite, weight etc..Experiment grade rat 120, weight (100 ± 20) g is taken, it is female It is male fifty-fifty, 4 groups, every group 30 are randomly divided by gender and weight.Observation group is divided into high, medium and low three dosage groups, is administered respectively Dosage gives 0.05,0.03,0.02g(for every 10g mouse and is respectively equivalent to 50 times of adult clinical equivalent dosage, 30 times, 20 Times), by successive administration 180 days, stomach-filling on the one 2 times, every minor tick 6h.And it is being administered the 90th day, the 180th day and is being discontinued extensive respectively At multiple 30th day, every group is cutd open and kills 10 rats.Rat body weight, food ration, fur, color and autonomic activities etc. are observed respectively General physical signs detects 12 physiochemical indices, 17 biochemical indicators and 28 histopathologic slides.The mouse of blank group is given Give same dose of distilled water, stomach-filling on the one 2 times, every minor tick 6h.
Rat long term toxicity test result: the influence of 1. pairs of rat general status: during administration 6 months and drug withdrawal 1 month, Behavioral activity, diet, excrement of animal etc. are showed no exception, have no that overt toxicity reacts, also have no rats death.Each administration group Animal each time weight respectively compared with naive animals weight, group difference is not statistically significant.2. pair hematology Influence: each dosage group animal hematology index of observation group has no notable difference compared with blank group.3. pair blood parameters Influence: each dosage group items biochemical indicator no significant difference compared with blank group of observation group.4. pathological examination: successive administration 90 days, 180 days and be discontinued restore 30 days after the observation of each organs and tissues of rat as a result, items institutional framework is normal, no abnormality seen Pathological change.Show that anaesthetic continuous 180 days large dosage of gastric infusions have no obvious toxic action to Rats Organs and Tissues.
In long term toxicity test, rat body weight, hematology and the biochemical indicator of 3 dosage groups, pathologic finding etc. are just In normal range, has no that overt toxicity reacts, show the anaesthetic without cumulative toxicity, clinical safety is reliable.
Six, pharmacological effect is tested:
The preparation of anaesthetic: excrementum pteropi 100g, rhizoma gymnadeniae 90g, radix polygonati officinalis 50g, radices trichosanthis 50g, lucid asparagus 50g, rhizoma polygonati 50g, meat are taken 10 parts of osmanthus (removing rough bark) g, Concretio Silicea Bambusae 10g mixing, Plus acidic ionized water impregnate 5min, filter out acid electrolyzed functional water, dry, pulverize At coarse powder, add alkali ion water, alkali ion water water there was not 1-2cm of medicinal material, continued after impregnating 30min, after boiled with high heat It uses mild fire instead, keeps slightly boiled, after decocting 20min, filtering obtains extracting solution, and the dregs of a decoction are decocted 2 times with alkali ion water again, merges 3 times Extracting solution, it is spare, it takes natural salt 10g, HALITUM PURPUREUM 10g to mix, crushes, sieve with 100 mesh sieve, it is spare, take honey 6000g, butter 5000g, milk 2500g, rock sugar 1000g, brown sugar 900g, natural salt 10g, HALITUM PURPUREUM 10g are added in extracting solution, are concentrated into nothing Moisture, present glossy pool, it is red-black transparent when, be made oily ball to get.
Strengthening by means of tonics, antifatigue experiment
Healthy adult is taken to test grade male mice 60, weight (20 ± 2g) is randomly divided into blank group, experimental group, and experimental group fills Stomach gives anaesthetic 15 days, and every 10g mouse is each taking 0.001g anaesthetic, and 2 times a day, blank group gives isometric water.After 15 days respectively Every mouse of blank group and experimental group is placed on the fixed rope in the both ends root long 5m, with stopwatch record mouse from just climb to Rope compares mouse rope climbing ability lasting on rope up to the time of landing, counts two groups of differences, is shown in Table 2.It again will be above-mentioned After mouse continues gastric infusion 3 days, mouse is placed in water tank, and adds 1.5g load in mouse tail, records mouse in water tank The time of interior swimming cannot be emerged as deadline again with mouse cascading water bottom, count two groups of differences.It the results are shown in Table 3.
The experimental results showed that experimental mice is averaged, the rope climbing time is significantly higher than blank group (P < 0.05).Experimental mice continues Swimming time is significantly higher than blank group (P < 0.05).Mouse, which takes anaesthetic, can significantly extend rope climbing time and swimming time.Show Anaesthetic has strengthening by means of tonics and antifatigue effect.
The influence of mouse normobaric hypoxia state lower time-to-live is tested:
Healthy adult is taken to test grade male mice 40, weight (20 ± 2g) is randomly divided into blank group and experimental group, and every group 20 Only, experimental group stomach-filling gives anaesthetic 15 days, and every 10g mouse is each taking 0.001g anaesthetic, and 2 times a day, blank group gives isometric water. All mouse are put into the closed wide-mouth bottle of 500ml after 15 days, 10g soda lime is put in wide-mouth bottle, absorb the titanium dioxide of exhalation Carbon and moisture, observe and record mouse breathing dwell time, and statistical result is shown in Table 4.
The result shows that: anaesthetic can significantly extend the time-to-live under anoxia in mice state.
Andrin-like action experiment:
Healthy adult is taken to test grade male rat, weight (100 ± 20) g, 40 are randomly divided into blank group and experimental group, and stomach-filling is given Medicine, every 10g rat is each taking 0.001g anaesthetic, 2 times a day, blank control group water supply, after continuous 15 days, etherization, cavity of resorption Venous blood sampling, collects anticoagulated blood, centrifuging and taking blood plasma, and radioimmunoassay surveys Testosterone.It the results are shown in Table 5.
The result shows that anaesthetic can dramatically increase the content of stosterone in rat plasma.
Seven, clinical test:
Volunteer 80 that the age is 55-85 years old are chosen, wherein male 56, female 24, average age 61.5 years old.It records Everyone every senile symptom and sign.Before taking anaesthetic, other all antiaging agents and nourishing agent are cut out, is taken medicine Period does not change eating habit and exercise method.
The preparation of anaesthetic: excrementum pteropi 100g, rhizoma gymnadeniae 90g, radix polygonati officinalis 50g, radices trichosanthis 50g, lucid asparagus 50g, rhizoma polygonati are taken 50g, 10 parts of g of cortex cinnamomi (removing rough bark), Concretio Silicea Bambusae 10g mixing, Plus acidic ionized water impregnate 5min, filter out acid electrolyzed functional water, do It is dry, it is ground into coarse powder, adds alkali ion water, alkali ion water water there was not 1-2cm of medicinal material, continues after impregnating 30min, uses force Baked wheaten cake uses mild fire instead after opening, keep slightly boiled, and after decocting 20min, filtering obtains extracting solution, and the dregs of a decoction decoct 2 with alkali ion water again It is secondary, merge No. 3 extracting solutions, it is spare, it takes natural salt 10g, HALITUM PURPUREUM 10g to mix, crushes, sieve with 100 mesh sieve, it is spare, take honey 6000g, butter 5000g, milk 2500g, rock sugar 1000g, brown sugar 900g, natural salt 10g, HALITUM PURPUREUM 10g are added to extracting solution In, be concentrated into no moisture, present glossy pool, it is red-black transparent when, be made oily ball to get.
Criterion of therapeutical effect: effective: the symptoms were significantly improved after treatment;Effective: symptom improves after treatment;It is invalid: symptom after treatment Without improvement.
Treatment method: 80 volunteer oral's anaesthetics, it is every to take 6g, 2 times a day.3 months are 1 course for the treatment of, continuously take 2 The course for the treatment of.Clinical observation and record are carried out to 80 volunteers referring to " screening specification and clinical evaluation of antiaging agent research ". It the results are shown in Table 6.
Obvious effective rate=effective number/total number of persons × 100%;Effective percentage=efficiently individual quantity/total number of persons × 100%;Inefficiency=invalid people Number/total number of persons × 100%;Total efficiently individual quantity=effective number+efficiently individual quantity;Total effective rate=total efficiently individual quantity/total number of persons × 100%。
As the result is shown: after 80 volunteers take 2 courses for the treatment of of anaesthetic, 9 senile symptoms have different degrees of change Kind, anaesthetic prescription can be improved life efficiency, improve constitution, delay organism physiology aging course, enhance immunocompetence and extension Service life can clinically reach preferable curative effect.
Second of embodiment: the therapeutic effect in order to enhance drug expands drug use groups, in the first embodiment On the basis of, increase 120-180 parts of anaesthetic myrobalan, 120-180 parts of Fructus meliae toosendan, 120-180 parts of pomegranate, gypsum rubrum (system) newly 120-180 parts, 52-78 parts of Bi Bi, 60-90 parts of cape jasmine, 44-66 parts of pepper, 40-60 parts of puncture vine (system), oriental wormwood 40-60 Part, 40-60 parts of cacumen biotae, 40-60 parts of Chinese ephedra, 40-60 parts of rhododendron leaves, 28-42 parts of Amomum cardamomum, 24-36 parts of galangal, 20-30 parts of Radix Ophiopogonis, 20-30 parts of safflower, 12-18 parts of nutmeg, 8-12 parts of cloves, 8-12 parts of tsaoko.Its processing method is such as Under:
Purified tap water is fitted into ionic water generator, by positive and negative electrode, respectively obtains alkali under the action of electric field Property ionized water and acid electrolyzed functional water, it is spare, 80-120 parts of excrementum pteropi, 72-108 parts of rhizoma gymnadeniae, radix polygonati officinalis 40-are taken by weight 60 parts, 40-60 parts of radices trichosanthis, 40-60 parts of lucid asparagus, 40-60 parts of rhizoma polygonati, 8-12 parts of cortex cinnamomi (removing rough bark), Concretio Silicea Bambusae 8- 12 parts, 120-180 parts of myrobalan, 120-180 parts of Fructus meliae toosendan, 120-180 parts of pomegranate, 52-78 parts of Bi Bi, cape jasmine 60-90 Part, 44-66 parts of pepper, 40-60 parts of puncture vine (system), 40-60 parts of oriental wormwood, 40-60 parts of cacumen biotae, 40-60 parts of Chinese ephedra, Du 40-60 parts of cuckoo leaf, 28-42 parts of Amomum cardamomum, 24-36 parts of galangal, 20-30 parts of Radix Ophiopogonis, 20-30 parts of safflower, nutmeg 12-18 parts, 8-12 parts of cloves, 8-12 parts of tsaoko mixing, Plus acidic ionized water impregnate 5min, filter out acid electrolyzed functional water, do It is dry, it is ground into coarse powder, adds alkali ion water, alkali ion water water there was not 1-2cm of medicinal material, continues after impregnating 30min, uses force Baked wheaten cake uses mild fire instead after opening, keep slightly boiled, and after decocting 20min, filtering obtains extracting solution, and the dregs of a decoction decoct 2 with alkali ion water again It is secondary, merge No. 3 extracting solutions, it is spare, 8-12 parts of natural salt, 8-12 parts of HALITUM PURPUREUM, gypsum rubrum (system) 120-are taken by weight 180 parts of mixing, crush, sieve with 100 mesh sieve, spare, take 4800-7200 parts of honey, 4000-6000 parts of butter, ox by weight 2000-3000 portions of milk, 720-1080 parts of brown sugar, 8-12 parts of natural salt, 8-12 parts of HALITUM PURPUREUM, is trembled with fear at 800-1200 parts of rock sugar 120-180 parts of water stone (system) is added in extracting solution, is concentrated into no moisture, and when being presented glossy damp, red-black transparent, oily ball is made, To obtain the final product.
Instructions of taking: adult is every to take 6g, 2 times a day.
Newly-increased anaesthetic component analysis:
Cloves, acrid flavour, slight bitter have dispelling cold conspicuous according to helping stomach fire, help digestion, whet the appetite, the effect of removing toxic substances, table rash, throat.Cloves It is lifeblood good medicine for one of six good medicine, there is good effect to dizzy, insomnia, asthma.
The effect of nutmeg, acrid flavour have and adjust stomach fire, help digestion, appetizing.It is vexed for fullness sensation in chest, it sighs, nervous, dizziness is lost Sleep etc..
Tsaoko, acrid flavour have dispel spleen, stomach cold and He Yi, the effect of helping stomach fire, help digestion.Tsaoko is the good medicine of spleen, be can be used for Each disease of spleen fever and chills.
Amomum cardamomum, acrid flavour, hardship have kidney of dispelling cold, and suppression is conspicuous according to adjusting stomach fire, help digestion, whet the appetite, the effect of antiemetic.Amomum cardamomum is It is conspicuous according to disease, kidney chronic illness, the dry disease in kidney Dagri etc. to can be used for kidney for the good medicine of kidney.
Gypsum rubrum, acrid flavour have and dispel bar up to xeothermic, antiemetic, and antidiarrheal helps digestion, and detoxifies, and breaks ruffian, nourish, detumescence, and synthetism is adjusted The effect of managing voxel.For malnutrition, anti-aging increases appetite, strengthens body.
Galangal, it is acrid flavour, sweet, there is conditioning stomach fire, appetizing helps digestion, and the Ba Dagan that dispels is conspicuous according to restraining purulence, phlegm, strengthening body The effect of.Cold, lumbocrural pain, physical decline, impotence, the diseases such as indigestion for kidney.
The effect of pepper, acrid flavour have conditioning stomach fire, help digestion, whet the appetite, and the Ba Dagan that dispels trembles with fear.Do not change for food, digestion is not Good, abdominal distension, iron dirt bar reaches dry etc..
Myrobalan, puckery have the effect of all diseases caused by three disadvantages of dispelling, conditioning voxel, removing toxic substances.For it is conspicuous according to, Xi La, bar Up to dry complication and all cards of polymerism, the side fit applications corresponding to each disease.
Fructus meliae toosendan, it is bitter, puckery, have the Ba Dagan that dispels is uncommon to draw, the effect of dry yellow water, analgesic, desinsection, improving eyesight.For alopecia, Painful swelling of joints, pruitus, red eye, swell pain etc..
The effect of cape jasmine, bitter have removing heat from blood, and improving eyesight, the Ba Dagan that dispels is uncommon to be drawn, and nourish strong and conditioning voxel.For Hepatopyretic disease, physically weak, few essence, spermatorrhea, diabete etc..
Puncture vine, sweet in flavor, bitter, have kidney of dispelling it is cold it is conspicuous according to, yang-tonifying, inducing diuresis to remove edema the effect of.For edema, oedema, urine It closes, frequent micturition, lumbago caused by deficiency of kidney, passes out semen, impotence is physically weak etc..
The effect of pomegranate, sweet in flavor, sour, with conditioning stomach fire, the Ba Dagan that dispels is cold to be demonstrate,proved, and is helped digestion, is whetted the appetite, antidiarrheal.For not disappearing Change disease, nausea, gasteremphraxis, borborygmus, belch, stomach, lung, kidney, cold card of liver etc..
Radix Ophiopogonis, sweet in flavor, bitter have the effect of Ping Xila, heat-clearing, removing toxic substances.For having a fever, headache, polydipsia, mesh, body, urine The hot uncommon drawing disease such as jaundice.
Bi Bi, acrid flavour have conditioning stomach fire, and the Ba Dagan that dispels is conspicuous according to conditioning voxel, strengthening by means of tonics is relievingd asthma, eliminating the phlegm, analgesic And other effects.It decays for stomach fire, do not feel like eating, kidney is cold, impotence, insomnia, in poor health etc..
Oriental wormwood, bitter, pungent, resolving sputum hot with clearing lung-heat, normalizing gallbladder to cure jaundice.For cough with lung heat, icterohepatitis etc..
Cacumen biotae, it is bitter, puckery, there is the effect of cool blood, hemostasis, clearing lung and relieving cough.For warm blood alopecia, cough with lung heat etc..
Chinese ephedra, it is bitter, puckery, there is removing heat from the liver, hemostasis breaks ruffian, cures the wound, and reduces swelling, the effect of sweating.For hepatic injury, spit Blood, traumatic hemorrhage, kidney arteries and veins shake wound etc..
Rhododendron leaves, it is sweet in flavor, bitter, puckery, there is conditioning stomach fire, appetizing, dispel Ba Dagan, analgesic, cough-relieving, and eliminating the phlegm is reduced swelling, and grows The effect of supporting, improving voxel.For indigestion disease, iron dirt Ba Dagan, physically weak, malnutrition is old and frail etc..
The effect of safflower, sweet in flavor, bitter have removing heat from the liver, and menstruation regulating is invigorated blood circulation, and is stopped blooding, and relieve pain, detumescence, nourish positive essence.With In liver disease, irregular menstruation, waist and leg ache etc..
It is compared with the first embodiment, the drug of the present embodiment expands application range, a variety of sub- strong to what is occurred in recent years Health type has exact curative effect.Present people's life and operating pressure are generally big, and spiritual high-pressure, rhythm of life is fast, adds It is in the radiation condition of computer, mobile phone and a variety of electronic products for a long time, can feel to feel exhausted, anxious, face Hold aging, mental depression, in addition cause endocrine disorder, immunity degradation and lead to the generations of various physiological maladies.In addition It states bulk pharmaceutical chemicals and forms new prescription, the state of mind of adjustable people relieves stress, and eliminates fatigue, and strengthen immunity prevents disease The generation of disease.
Clinical curative effect analysis:
In December, 2017 in December, 2016-is chosen at volunteer 118 of the progress health examination of Hospital Physical Examination center, male 70 Name, the age 35-68 years old, average age 45.2 years old, meets the diagnostic criteria of fatigability inferior health, and use by women 48 Fatigue scale-14 (FS-14) evaluates fatigue conditions, and score is all larger than 3.The diagnostic criteria of fatigability inferior health: 1. Main Diagnosis Standard: (1) lasting or recurrent exerbation fatigue continues at 6 months or more;(2) it is checked and is tied according to medical history, sign or laboratory Fruit can exclude the various organic diseases for causing confirmed fatigue.2. symptom standard: (1) physical strength or mental load is overweight causes It is not easy the fatigue released;(2) muscle of not clear reason is powerless;(3) insomnia is generally existing, or has dreaminess and early awakening; (4) alliteration, giddy or headache;(5) difficult concentrating, failure of memory;(6) loss of appetite;(7) shoulder back discomfort, chest There is girdle sensation in portion, or has lumbago, the myalgia of delocalization and arthralgia, without specific rheumatism or trauma history;(8) feel depressed, Anxiety or anxiety, fear;(9) interest decline or forfeiture;(10) hypogona dism;(11) low-heat;(12) dry throat, pharyngalgia or throat There is girdle sensation.
The preparation of anaesthetic: purified tap water is fitted into ionic water generator, by positive and negative electrode, in the work of electric field Alkali ion water and acid electrolyzed functional water are respectively obtained under, it is spare, 80-120g of excrementum pteropi, rhizoma gymnadeniae 72-are taken by weight 108g, 40-60g of radix polygonati officinalis, 40-60g of radices trichosanthis, 40-60g of lucid asparagus, 40-60g of rhizoma polygonati, 8-12g of cortex cinnamomi (removing rough bark), 8-12g of Concretio Silicea Bambusae, 120-180 parts of myrobalan, 120-180 parts of Fructus meliae toosendan, 120-180 parts of pomegranate, 52-78 parts of Bi Bi, cape jasmine 60-90 parts, 44-66 parts of pepper, 40-60 parts of puncture vine (system), 40-60 parts of oriental wormwood, 40-60 parts of cacumen biotae, Chinese ephedra 40-60 Part, 40-60 parts of rhododendron leaves, 28-42 parts of Amomum cardamomum, 24-36 parts of galangal, 20-30 parts of Radix Ophiopogonis, 20-30 parts of safflower, meat 12-18 parts of cardamom, 8-12 parts of cloves, 8-12 parts of tsaoko mixing, Plus acidic ionized water impregnate 5min, filter out acid ion Water is dried, crushed into coarse powder, adds alkali ion water, and alkali ion water water there was not 1-2cm of medicinal material, continues after impregnating 30min, It uses mild fire after boiled with high heat instead, keeps slightly boiled, after decocting 20min, filtering obtains extracting solution, the dregs of a decoction use alkali ion decocting again It boils 2 times, merges No. 3 extracting solutions, it is spare, 8-12g of natural salt, 8-12g of HALITUM PURPUREUM, gypsum rubrum (system) 120-are taken by weight 180g mixing, crushes, sieves with 100 mesh sieve, spare, takes 4800-7200g of honey, 4000-6000g of butter, milk by weight 2000-3000g, 800-1200g of rock sugar, 720-1080g of brown sugar, 8-12g of natural salt, 8-12g of HALITUM PURPUREUM, gypsum rubrum (system) 120-180g is added in extracting solution, is concentrated into no moisture, present glossy pool, it is red-black transparent when, be made oily ball to get. Adult is every to take 6g, 2 times a day.
Criterion of therapeutical effect: cure: symptom disappears after treatment;Effective: symptom improves after treatment;Invalid: treatment symptom is without improvement.
Treatment method: 118 volunteer oral's anaesthetics, it is every to take 6g, 2 times a day.3 months are 1 course for the treatment of, continuously take 2 A course for the treatment of.Treatment results are shown in Table 7.
Cure rate=healing number/total number of persons × 100%;Effective percentage=efficiently individual quantity/total number of persons × 100%;Inefficiency=invalid people Number/total number of persons × 100%;Total efficiently individual quantity=effective number+efficiently individual quantity;Total effective rate=total efficiently individual quantity/total number of persons × 100%。
As the result is shown: anaesthetic is to the muscle inability of 118 fatigability inferior health volunteers, sexual hypoesthesia, dizzy alliteration, mistake Dormancy dreaminess, anxiety and tense, food indigestion, mouth parched and tongue scorched, throat discomfort, the symptoms such as have a pain in the back total effective rate be respectively 93.88%, 83.11%, 95.74%, 94.32%, 84.78%, 97.15%, 97.56%, 93.33%, 96.43%, illustrate anaesthetic to 118 Name fatigability inferior health volunteer has clinically reached good therapeutic effect.

Claims (5)

1. a kind of anaesthetic for strengthening by means of tonics, it is characterised in that: the raw material medicaments in part by weight of the anaesthetic matches are as follows: honey 4800-7200 parts, 4000-6000 parts of butter, 2000-3000 parts of milk, 800-1200 parts of rock sugar, brown sugar 720-1080 Part, 80-120 parts of excrementum pteropi, 72-108 parts of rhizoma gymnadeniae, 40-60 parts of radix polygonati officinalis, 40-60 parts of radices trichosanthis, lucid asparagus 40-60 Part, 40-60 parts of rhizoma polygonati, 8-12 parts of cortex cinnamomi (removing rough bark), 8-12 parts of Concretio Silicea Bambusae, 8-12 parts of natural salt, HALITUM PURPUREUM 8-12 Part.
2. a kind of anaesthetic for strengthening by means of tonics according to claim 1, it is characterised in that: the bulk pharmaceutical chemicals of the anaesthetic are pressed Weight are as follows: 6000 parts of honey, 5000 parts of butter, 2500 parts of milk, 1000 parts of rock sugar, 900 parts of brown sugar, excrementum pteropi 100 Part, 90 parts of rhizoma gymnadeniae, 50 parts of radix polygonati officinalis, 50 parts of radices trichosanthis, 50 parts of lucid asparagus, 50 parts of rhizoma polygonati, 10 parts of cortex cinnamomi (removing rough bark), Concretio Silicea Bambusae 10 parts, 10 parts of natural salt, 10 parts of HALITUM PURPUREUM.
3. a kind of preparation process of the anaesthetic for strengthening by means of tonics as claimed in claim 1 or 2, it is characterised in that: will purify Tap water afterwards is fitted into ionic water generator, by positive and negative electrode, respectively obtained under the action of electric field alkali ion water and Acid electrolyzed functional water, it is spare, radix polygonati officinalis, radices trichosanthis, lucid asparagus, rhizoma polygonati, cortex cinnamomi (removing rough bark), Concretio Silicea Bambusae, rhizoma gymnadeniae, excrementum pteropi is mixed It closes, Plus acidic ionized water, impregnates 5min, filter out acid electrolyzed functional water, be dried, crushed into coarse powder, add alkali ion water, alkali ion Water water there was not 1-2cm of medicinal material, continues after impregnating 30min, uses mild fire after boiled with high heat instead, keeps slightly boiled, decocts 20min Afterwards, it filtering, obtains extracting solution, the dregs of a decoction are decocted 2 times with alkali ion water again, merge No. 3 extracting solutions, and it is spare, by natural salt, HALITUM PURPUREUM Mixing is crushed, is sieved with 100 mesh sieve, spare, and butter, milk, honey, brown sugar, rock sugar, natural salt, HALITUM PURPUREUM are added to extracting solution In, be concentrated into no moisture, present glossy pool, it is red-black transparent when, be made oily ball to get.
4. a kind of anaesthetic for strengthening by means of tonics according to claim 1, it is characterised in that: the raw material medicaments in part by weight 120-180 parts of myrobalan, 120-180 parts of Fructus meliae toosendan, 120-180 parts of pomegranate, 120-180 parts of gypsum rubrum (system), Bi Bi is added 52-78 parts, 60-90 parts of cape jasmine, 44-66 parts of pepper, 40-60 parts of puncture vine (system), 40-60 parts of oriental wormwood, cacumen biotae 40-60 It is part, 40-60 parts of Chinese ephedra, 40-60 parts of rhododendron leaves, 28-42 parts of Amomum cardamomum, 24-36 parts of galangal, 20-30 parts of Radix Ophiopogonis, red Spend 20-30 parts, 12-18 parts of nutmeg, 8-12 parts of cloves, 8-12 parts of tsaoko.
5. a kind of preparation process of the anaesthetic for strengthening by means of tonics as claimed in claim 4, it is characterised in that: will be purified Tap water is fitted into ionic water generator, by positive and negative electrode, respectively obtains alkali ion water and acidity under the action of electric field Ionized water, it is spare, by radix polygonati officinalis, radices trichosanthis, lucid asparagus, rhizoma polygonati, cortex cinnamomi (removing rough bark), Concretio Silicea Bambusae, rhizoma gymnadeniae, excrementum pteropi, myrobalan, Fructus meliae toosendan, cape jasmine, puncture vine (system), pomegranate, galangal, Radix Ophiopogonis, Amomum cardamomum, Bi Bi, oriental wormwood, pepper, cacumen biotae, Chinese ephedra, cuckoo Leaf, nutmeg, safflower, cloves, tsaoko mixing, Plus acidic ionized water impregnate 5min, filter out acid electrolyzed functional water, be dried, crushed into Coarse powder adds alkali ion water, and alkali ion water water there was not 1-2cm of medicinal material, continues after impregnating 30min, changes after boiled with high heat With mild fire, keep slightly boiled, after decocting 20min, filtering obtains extracting solution, and the dregs of a decoction are decocted 2 times with alkali ion water again, merges 3 times and mentions Liquid is taken, it is spare, natural salt, HALITUM PURPUREUM, gypsum rubrum (system) are mixed, crushes, sieves with 100 mesh sieve, it is spare, by butter, milk, bee Honey, brown sugar, rock sugar, natural salt, HALITUM PURPUREUM, gypsum rubrum (system) are added in extracting solution, are concentrated into no moisture, present glossy pool, When red-black transparent, be made oily ball to get.
CN201811650301.3A 2018-12-31 2018-12-31 A kind of anaesthetic and its preparation process for strengthening by means of tonics Pending CN109453317A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110559345A (en) * 2019-09-06 2019-12-13 漳州卫生职业学院 health-care electuary for relieving pain of menstruation cold syndrome and preparation method thereof
CN110812468A (en) * 2019-12-16 2020-02-21 额尔敦毕力格 Gymnadenia conopsea-37-flavor Mongolian medicinal ointment formula and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110559345A (en) * 2019-09-06 2019-12-13 漳州卫生职业学院 health-care electuary for relieving pain of menstruation cold syndrome and preparation method thereof
CN110812468A (en) * 2019-12-16 2020-02-21 额尔敦毕力格 Gymnadenia conopsea-37-flavor Mongolian medicinal ointment formula and preparation method thereof

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