CN103977084A - Traditional Chinese medicine preparation capable of promoting urination and freeing strangury and preparation method thereof - Google Patents
Traditional Chinese medicine preparation capable of promoting urination and freeing strangury and preparation method thereof Download PDFInfo
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- CN103977084A CN103977084A CN201410173512.8A CN201410173512A CN103977084A CN 103977084 A CN103977084 A CN 103977084A CN 201410173512 A CN201410173512 A CN 201410173512A CN 103977084 A CN103977084 A CN 103977084A
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Abstract
The invention relates to a traditional Chinese medicine preparation capable of promoting urination and freeing strangury and a preparation method thereof. The traditional Chinese medicine preparation is made of the following raw materials in parts by weight: 5 to 10 parts of baeckea frutescens, 10 to 20 parts of plantain, 20 to 30 parts of desmodium, and 5 to 15 parts of tetrapanax papyriferus. The raw materials can be made into powder, granules, capsules, liquid, suspension, or other medicinal dosages. The preparation can effectively prevent and treat symptoms caused by kidney diseases and urine tract infection such as oliguria, anuria, difficulty in urination, and the like, and has the advantages of rapid effect and no side effect. The successful development of the preparation has an important meaning in the field of traditional Chinese medicine diuretics treatment.
Description
Technical field
The present invention relates to Chinese herbal and crude drugs preparations technical field, be specially a kind of Chinese medicine preparation for the treatment of inducing diuresis for treating stranguria syndrome and preparation method thereof.
Background technology
Quickening along with urbanization process, social life rhythm is accelerated now, work, life stress invisible be centered around us at one's side, the increasing person is in overdraw, excessive psychological burden, the erratic people of living habit, as irregular in sing karaoke all night, the life such as play Mah-Jong, do not go home all night, body constitution acidify is increased the weight of in capital, easily suffers from diabetes; In addition, bad living habit, as sitting, suppress urine, Sal for a long time and too much also can cause human kidney over-burden, if things go on like this, human body autoimmune systemic-function and resistance against diseases decline, and not only easily cause injury of bladder, also there will be edema, often with eyelid, starting (having some patients were edema first from lower limb), even there is hydrothorax and ascites in the serious whole body that involves.Hypertension is one of nephropathy performance.Frequent micturition (often), urgent micturition (can't help doing urine), dysurea (lower abdomen and urethralgia while urinating).Lumbago, great majority are dull pain, can there is violent angor in surgical disease.Oliguria or anuria are often less than round the clock 400 milliliters and are oliguria, are less than 100 milliliters and are anuria.Polyuria, often surpasses 2500 milliliters round the clock and is polyuria.Hematuria, contains hemocyte in urine, or occult blood positive (having plus sige) is shown in chemical examination.In urine, how foam may be the performance that urine protein increases, and chemical examination urine protein positive is the admissible evidence that urine protein increases.Other as being off one's feed, weak, pale complexion etc.There is renal insufficiency, uremia's series of clinical manifestations late period in various nephropathy.This just needs the human body can diuresis toxin expelling, as early as possible toxin is excreted, and recovers renal function.
Diuresis principle refers to when blood vessel osmotic pressure forces down than the infiltration of kidney peripheral blood vessel in kidney, easily absorbs peripheral blood vessel moisture content, and reduce in kidney osmotic pressure with medicine, makes it absorb moisture content to increase, and the discharge that makes urine increases and reaches the effect of diuresis.And the disease that affects human body urinary function comprises prostatitis, nephritis and diabetes etc.Prostatitic symptom is: high heat, shiver with cold, acute urinary retention, urgent micturition, frequent micturition, dysurea, abscess, prostatic hyperplasia perineal position pain etc.; The symptom of nephritis is: facial edema, oliguria, anuria, hematuria, companion's albuminuria, intermittent hematuria, lower limbs edema, hypertension etc.; The symptom of diabetes is: polyuria, and polydipsia, excessive thirst polydipsia, increases in right amount, loses weight, and becomes thin, weak, blood sugar increasing etc.
According to its diuresis usefulness, diuretic is divided into high-effect, middle usefulness and 3 grades of low usefulness clinically: 1. high ceiling diuretic.Claim again loop of Henle diuretic.The most frequently used is furosemide, and ethacrynate sodium is used less, may be larger because of its side effect.Bumetanide effect is stronger.2. middle usefulness diuretic.The most frequently used is thiazide diuretic, as Hydrochlorothiazide.3. low ceiling diuretic.Claim again potassium-sparing diuretic.Normal and phenothiazine drug use in conjunction.Increase thiazide curative effect on the one hand, reduce on the other hand the discharge of potassium.There are aldactone (claiming again spironolactone), triamterene, amiloride.Still there is in addition osmotic diuretic.Organic mercury diuretic (as mersalyl) is eliminated greatly because of toxicity.A little less than carbonic anhydrase inhibitors (as acetazolamide) diuresis, ophthalmology, for reducing intraocular pressure, is treated glaucoma etc. at present.These Western medicine diuretic toxic and side effects are large above, and expensive, and are not suitable for most people use.At present, treat urinary disease on market, also more for the Chinese medicine preparation of diuresis, its therapeutic effect is also sure.But treatment cycle is long, diuretic effect is very indefinite, and patient conventionally has the demand for the treatment of as early as possible after taking, to remove slight illness, recovers normal work and life.Therefore, develop a kind of fast and effectively, cheaply, there is diuresis row and drench the Chinese medicine preparation of effect and seem particularly important.
Summary of the invention
The object of the invention is for above-mentioned prior art not enough and propose a kind of fast and effectively, cheaply, there is diuresis row and drench effect, have no side effect, can effectively effect a radical cure that urine nasal obstruction is obstructed, nerve urine retention, bladder inflammation, lithangiuria, injury of urinary tract and the oliguria causing for renal insufficiency, anuria.
The present invention realizes by the following technical solutions:
The Chinese medicine preparation of inducing diuresis for treating stranguria syndrome of the present invention, by the raw material of following parts by weight, made:
Folium Baeckeae 5-10 part
Herba Plantaginis 10-20 part
Herba Lysimachiae 20-30 part
Medulla Tetrapanacis 5-15 part.
Preferably, the Chinese medicine preparation of described inducing diuresis for treating stranguria syndrome, by the raw material of following parts by weight, made:
Folium Baeckeae 6-8 part
Herba Plantaginis 12-18 part
Herba Lysimachiae 22-28 part
Medulla Tetrapanacis 8-12 part.
Preferably, the Chinese medicine preparation of described inducing diuresis for treating stranguria syndrome, by the raw material of following parts by weight, made:
7 parts of Folium Baeckeaes
15 parts of Herba Plantaginiss
25 parts of Herba Lysimachiaes
10 parts of Medulla Tetrapanaciss
Analysis of effective component in the above-described Chinese medicine preparation that is used for the treatment of inducing diuresis for treating stranguria syndrome is as follows:
1, Folium Baeckeae (
baeckea frutescensl), belong to Dicotyledoneae, original perianth subclass, Myrtales, Myrtaceae, Leptospermoideae Xi Zi family, Folium Baeckeae belongs to.Folium Baeckeae leaf is containing volatile oil, main component is australene (α-pinene), to P-cymene (p-cymene), trans carveol (trans-carneol), myrtanal (myrtenal), cineole (cineole), Eucarvone (d-carnone), limonene (limonene), α-(king is ancient) (king's bar) alkene (α-copaene), linalool (linalool), 4-terpinenol (4-terpinenol), Jin Zhong analyses alcohol (occidentalol), guaiaci lignum regretful (guaiazulene), Borneolum Syntheticum (borneol), pull aromatic (elemol), nerol (nerol), thymol (thy-mol), Flos Caryophylli alkene (caryophyllene), CAOPU alkene (calamenene), 19 kinds of the clear casket alcohol of Bi (cadinol) etc.Bitter in the mouth; Pungent; Cool in nature.Blood-activating analgetic; Heat clearing away unit of weight measurement, about six liang poison; Inducing diuresis for treating stranguria syndrome; Killing parasites for relieving itching.Cure mainly traumatic injury; Tripe sclerosis; Diarrhea of heat type; Pyretic stranguria; Dysuria; Pudendal pruritus; Foot gas; Eczema; Skin pruritus; Scabies; Burn due to hot liquid or fire; Worm venom.1. < < Guangzhou flora > >: control calentura.2. < < Luchuan book on Chinese herbal medicine > >: detumescence, pain relieving, blood stasis removing, parasite killing.Control traumatic injury stupor, scabies, ulcer, venom.3. < < Nanning City medicine will > >: convergence, parasite killing, hemostasis, pain relieving, granulation promoting.With washing skin infection, pruritus.4. < < Guangxi Chinese medicinal herbal > >: have diuresis promoting effect.Control bladder heat, dysuria, pudendal pruritus, skin steam.Decoct that washing skin is rottenly itched, eczema; Leaf, smashes depositedly, controls Scolopendra wound, branch and leaf, and steam oil, controls skin ulcer leprosy etc.
2, Herba Plantaginis (
plantagoasiatical;
plantagodepressawilld), have another name called wheel dish, grass is filled with in field, for Plantaginaceae herbaceos perennial, belongs to Plantaginaceae, Plantago L..[nature and flavor] are sweet, cold.[return through] returns liver, kidney, lung, small intestine meridian.Clearing away heat and promoting diuresis, removing heat from blood, removing toxic substances.Cure mainly accumulation of heat in the urinary bladder, dysuria, stranguria with turbid discharge leukorrhagia, heat-damp in summer dysentery, epistaxis, hematuria, liver-heat conjunctival congestion, laryngopharynx swelling and pain, carbuncle sore tumefacting virus.Herb is containing plantagin (Plantago astiatice L), aucubin (Aucnbin), ursolic acid (Uraolicacid), B-sitosterol, Palmic acid B-paddy steroid acid esters, brown tamarind sterol ester, vitamin B, vitamin C and plantaglucide (Plantaglusidc) (being to be comprised of D-gala aldehydic acid methyl ester .D-half sugar, L-arabinose, L-rhamnose etc.).Protein, succinic acid, adenine, choline, catalpol, stearic acid, arachidic acid, linolenic acid, Asia there are not the fatty acids such as acid.Herba Plantaginis is sweet in flavor and cold in property, the effect of have diuretic, heat clearing away, improving eyesight, eliminating the phlegm.Cure mainly gonorrhea, hematuria, urinary obstruction, yellow cellulitis, edema, hematodiarrhoea, have loose bowels, conjunctival congestion and swelling pain, laryngalgia etc.< < grass opinion > > carry " control hematuria, can tonifying five ZANG-organs, improving eyesight, the little Herba Plantaginis of drying of profit just, logical five types of stranguria ".< < book on Chinese herbal medicine meets former > > to carry " if empty spermatorrhea gas is not consolidated person's forbidding ".Nature and flavor and function are sweet, cold, return the hands sun, Yangming Channel.Diuretic, heat clearing away, improving eyesight, eliminates the phlegm, for urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, jaundice, edema, hematodiarrhoea is had loose bowels, epistaxis, conjunctival congestion and swelling pain, laryngalgia, cough, skin ulcer.
3, Herba Lysimachiae (
dichondra repensforst), original name Herba Dichodrae, another name: Lysimachia christinae Hance, Drymoglossum subcordatum, Cui Pingcao, lotus bud grass, Boiled small dumplings with pork are careless, JINSUOSHI etc., belong to Metachlamydeae tubular flower order, Convolvulaceae, Horse hoof metal.Meridian distribution of property and flavor: sweet in the mouth, bitter in the mouth, cool in nature; Return liver, kidney, urinary bladder channel.Effect: relieving stranguria by diuresis; Heat-clearing and toxic substances removing; Dissipating blood stasis for subsidence of swelling.Cure mainly liver and gall and urinary system calculus; Pyretic stranguria; Oedema due to nephritis; Jaundice due to damp-heat; Sore carbuncle; Venom; Traumatic injury.Application compatibility: for liver and bile stone and lithangiuria, pyretic stranguria, jaundice.Herba Lysimachiae has good dampness removing jaundice eliminating and the treating stranguria effect of calculus, and treating the liver cholelithiasis and jaundice can be decocted soup for tea-drinking by alone these product, or compatibility Herba Artemisiae Scopariae, Radix Curcumae, Radix Et Rhizoma Rhei etc. are to strengthen clearing liver-gallbladder and calculus effect.Control stranguria caused by urinary stone, pyretic stranguria and also can alonely get effect or be equal to use with Spora Lygodii, Endothelium Corneum Gigeriae Galli, Folium Pyrrosiae, to strengthen the merit of clear damp-heat in lower-JIAO, Tonglin Paishi; Stranguria caused by urinary stone has the proposita of suffering from a deficiency of the kidney concurrently, can with the compatibility application such as the Herba Taxilli of the kidney invigorating, semen juglandis.For sore carbuncle, acute mastitis, erysipelas, venom and traumatic injury.Herba Lysimachiae has removing toxic substances dissipating blood stasis, the merit of reducing swelling and alleviating pain, and conventional fresh goods is taken orally or external application, can smash juice drink by alone fresh grass, or smash deposited affected part, also can be equal to strengthen antipyretic and antidote functions with Flos Chrysanthemi Indici, Herba Taraxaci, Rohdea japonica Roth.In addition, Herba Lysimachiae is used for edema, tympanites, merit for oral administration, external application all has inducing diuresis to remove edema, and for cough due to lung-heat, infantile hyperpyrexia, is to get its antipyretic and antidote functions.
Medical value: herb hyoscine, has the merit of clearing away heat and promoting diuresis, wind-expelling pain-stopping, hemostasia and promoting granulation, eliminating inflammation and expelling toxin, parasite killing.Can treating acute and chronic hepatitis, icterohepatitis, cholecystitis, nephritis, urinary system infection, tonsillitis, stomatitis and carbuncle furuncle are treated poison, venom, acute mastitis, dysentery, malaria, pneumorrhagia etc.A, calculus effect: Herba Lysimachiae has cholagogic and lithagogue and diuresis and expelling stone effect.The main component Calcium oxalate (CaC2O4) monohydrate CaC of polysaccharide component in the alcohol-insoluble substances of Herba Lysimachiae to lithangiuria
2o
4h
2the crystallization of O has inhibitory action.And inhibitory action increases with the increase of concentration.Herba Lysimachiae also can make blood, urine slant acidity, makes the litholysis that could exist in alkaline environment.CaC slows down
2o
4h
2o growth rate, reduces the degree of crystal accumulation, thereby is conducive to treat calculus.By modern clinic extensive use and obtain good result.B, choleretic effect: pharmacology and clinical confirmation truly have choleretic effect, choleretic effect may be to promote hepatocyte secretion of bile, and bile in liver and gall is increased, intrinsic pressure increasing, Oddi's sphincter is lax, causes bile excretion to increase.Thrombosis inhibitory action Lysimachia herb total flavone can significantly alleviate the thrombotic weight in wet base of rat body angular vein and dry weight under pathological state, reduces thrombotic percentage rate, demonstrates significant thrombosis inhibitory action.C, immune system effect Herba Lysimachiae is had to inhibitory action to cellular immunization, can strengthen the phagocytic function of mouse macrophage.Herba Lysimachiae is useful as the immunosuppressant of organ transplantation or self-immunological diseases.
4, Medulla Tetrapanacis (
tetrapanax papyriferus), another name bandit is de-, from southern, Huo Tuo, lean on business etc., be the stem pith of Araliaceae rice-paper plant, belong to Dicotyledoneae, original perianth subclass, Ranales, Araliaceae, rice-paper plant belongs to.Nature and flavor: sweet in the mouth; Light; Cold nature.1. < < Bencao Shiyi > >: nontoxic.2. < < medicine origin > >: gas is flat, sweet in the mouth.3. < < book on Chinese herbal medicine covers bamboo fish trap > >: slightly sweet flavor, gas is flat.4. < < detailed outline > >: sweet light, cold, nontoxic.Gui Jing: enter lung, stomach warp.1. < < detailed outline > >: enter lunar lung, positive bright stomach warp.2. < < Thunder God is concocted property of medicine solution > >: enter lung, large and small intestinal three warps.3. < < Bencao Jingshu > >: enter few cloudy, the sun of foot, few cloudy, the sun of hands.Efficacy effect: wet clearly diuretic; Lactogenesis.The puckery pain of main stranguria; Dysuria; Edema; Jaundice; Damp-warm diseases; Oliguria with reddish urine; Puerperal, breast was few; Amenorrhea; Leukorrhagia.For hygropyrexia dark coloured urine, the puckery pain of gonorrhea, edema oliguria, agalactia.[3] 1. < < Japan hanako materia medica > >: improving eyesight, bring down a fever, expedite the emergence of lower eyelid, stimulating milk secretion.2. < < Bencao Tujing > >: diuresis, hold concurrently and separate all poison of drug.3. < < medicine origin > >: except the edema difficulty in urination, control five types of stranguria.< < cures mainly secret formula > > cloud, eliminating the pathogens from the lung.4. < < book on Chinese herbal medicine narrow-necked earthen jar is wanted > >: control blurred vision deafness, nasal obstruction aphonia.5. < < Changsha medicine solution > >: stimulate the menstrual flow and close, treat jaundice, eliminating carbuncle cellulitis, sharp nose carbuncle, except vexed.
The Chinese medicine preparation of described inducing diuresis for treating stranguria syndrome is powder, granule, capsule, liquor, dry outstanding agent or other pharmaceutically useful exterior-applied formulation.
The preparation method of described powder is: by weight by dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae, Medulla Tetrapanacis coarse pulverization, then be crushed to below 100 orders, then with plastic bag vacuum packing, obtain powder.
The preparation method of described granule is: by weight dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae and Medulla Tetrapanacis being pulverized is 100 order coarse powder, add appropriate dextrin, PEG400 and appropriate amount of purified water, extruding or mist projection granulating, pack with opaque plastics bottle evacuation, obtains granule.
Described dextrin and PEG400 play adjuvant, improve taste and cementation in the preparation process of granule, the Chinese medicinal granule mouthfeel of preparing with these two kinds of adjuvants is good, is difficult for fragmentation, and the shelf life life-span is long, quality long shelf-life, and to effective ingredient without decomposition.
The preparation method of described capsule has two kinds:
A, described powder is pressed to method preparation described in claims 4, standby; Take edible Gelatinum oxhide, guar gum, glycerol, sodium alginate and pure water as rubber raw material, through changing glue, mixing the acquisition glue that heats up, then powder and glue are carried out to pelleting, setting, dry, packing, obtains.
B, will be by weight dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae and Medulla Tetrapanacis to be pulverized be 100 order coarse powder, and the pure water that adds 2-6 doubly to measure, decocts 20-40 minute, naturally be cooled to 20-45 ℃, filter, obtain filtrate, concentrating under reduced pressure, the density concentrated solution that is 1.12-1.15, concentrated solution is mixed to pelleting, setting, dry with the glue that step a makes, packing, obtains.
Preferably, b, will be by weight dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae and Medulla Tetrapanacis to be pulverized be 100 order coarse powder, the pure water that adds 3-5 doubly to measure, decoct 30 minutes, be naturally cooled to 35 ℃, filter, obtain filtrate, concentrating under reduced pressure, obtains the concentrated solution that density is 1.13-1.14, and concentrated solution is mixed with the glue that step a makes, pelleting, setting, dry, packing, obtains.
The preparation method of described liquor is: by weight dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae and Medulla Tetrapanacis being pulverized is 100 order coarse powder, the pure water that adds 2-6 doubly to measure, decoct 20-40 minute, naturally be cooled to 20-45 ℃, filter, obtain filtrate, add antiseptic, sterilization, after sterilization, vacuum packaging and get final product.
Preferably, the preparation method of described liquor is: by weight dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae and Medulla Tetrapanacis being pulverized is 100 order coarse powder, the pure water that adds 3-5 doubly to measure, decocts 30 minutes, is naturally cooled to 35 ℃, filter, obtain filtrate, add antiseptic, sterilization, after sterilization, vacuum packaging and get final product.
The preparation method of described dry outstanding agent is: by weight dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae and Medulla Tetrapanacis being pulverized is 100 order coarse powder, the pure water that adds 2-6 doubly to measure, decoct 20-40 minute, be naturally cooled to 20-45 ℃, remove filtering residue, filter, obtain filtrate, concentrating under reduced pressure obtains the extractum that density is 1.13-1.14, the dry fine grained that to obtain of spraying, after adding dextrin, food starch, be crushed to 200-400 order, vacuum packaging and get final product.
Preferably, the preparation method of described dry outstanding agent is: by weight dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae and Medulla Tetrapanacis being pulverized is 100 order coarse powder, and the pure water that adds 3-5 doubly to measure, decocts 30 minutes, naturally be cooled to 35 ℃, remove filtering residue, filter, obtain filtrate, concentrating under reduced pressure obtains the extractum that density is 1.13-1.14, the dry fine grained that to obtain of spraying, is crushed to 400 orders after adding dextrin, food starch, vacuum packaging and get final product.
Above-mentioned Chinese medicine of the present invention, according to different situations and pharmaceutical factory condition, can also make other preparation.
The application of the Chinese medicine preparation of inducing diuresis for treating stranguria syndrome in the medicine of the logical woods of preparation diuresis, is characterized in that: be included in preparation spleen invigorating eliminating dampness by diuresis, diuresis, improve renal function, discharge the application of the medicine of renal calculus.Can treat the symptoms such as lithangiuria, cystitis, urinary tract infection, urgent micturition frequent micturition, chronic nephritis, renal calculus.
The invention has the beneficial effects as follows:
1, the present invention develops diuresis row is drenched Chinese medicine preparation, inaccessible to the urine being caused by prostatitis, cystitis, urinary tract infection, chronic renal insufficiency, drop not under, oliguria, the symptoms such as anuria have good therapeutic effect.
2, use that 1-2 of the present invention is monthly can effectively be alleviated, total effective rate reaches more than 99%, and human body is had no side effect, easy to use, and cost is with low.
3, the present invention can prepare the several formulations forms such as granule, liquor, powder, dry suspending agent, capsule, and using method is various, the multiple instructions of taking such as can take after mixing it with water, directly take.
4, the relative Western medicine diuretic of the present invention toxic and side effects is little, and cost is low, and applicable crowd is wide, through inventor's checking, each age group crowd is all had to good therapeutic effect.
5, raw material of Chinese medicine Folium Baeckeae required for the present invention, Herba Plantaginis, Herba Lysimachiae and Medulla Tetrapanacis wide material sources, can artificial growth, and required Chinese crude drug almost Herb can be used as medicine, and utilization rate is high, and nonstaining property side-product produces.
the specific embodiment:
embodiment 1: the preparation of inducing diuresis for treating stranguria syndrome Chinese medicine powder
Formula:
7 parts of Folium Baeckeaes
15 parts of Herba Plantaginiss
25 parts of Herba Lysimachiaes
10 parts of Medulla Tetrapanaciss
More than the powder preparation method of formula is:
The preparation method of powder is: by weight by dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae, Medulla Tetrapanacis coarse pulverization, then be crushed to below 100 orders, then with plastic bag vacuum packing, obtain powder.
embodiment 2: the preparation of inducing diuresis for treating stranguria syndrome Chinese medicine granules
Formula:
8 parts of Folium Baeckeaes
12 parts of Herba Plantaginiss
20 parts of Herba Lysimachiaes
10 parts of Medulla Tetrapanaciss
The preparation method of granule is: by weight dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae and Medulla Tetrapanacis being pulverized is 100 order coarse powder, add appropriate dextrin, PEG400 and appropriate amount of purified water, extruding or mist projection granulating, pack with opaque plastics bottle evacuation, obtains granule.
embodiment 3: the preparation of inducing diuresis for treating stranguria syndrome Chinese medicinal capsule
Formula:
5 parts of Folium Baeckeaes
10 parts of Herba Plantaginiss
20 parts of Herba Lysimachiaes
5 parts of Medulla Tetrapanaciss
The preparation method of capsule has two kinds:
A, by preparing powder in embodiment 1, by flow process, prepare, standby; Take edible Gelatinum oxhide, guar gum, glycerol, sodium alginate and pure water as rubber raw material, through changing glue, mixing the acquisition glue that heats up, then powder and glue are carried out to pelleting, setting, dry, packing, obtains.
B, will be by weight dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae and Medulla Tetrapanacis to be pulverized be 100 order coarse powder, and the pure water that adds 2-6 doubly to measure, decocts 20-40 minute, naturally be cooled to 20-45 ℃, filter, obtain filtrate, concentrating under reduced pressure, the density concentrated solution that is 1.12-1.15, concentrated solution is mixed to pelleting, setting, dry with the glue that step a makes, packing, obtains.
embodiment 4: the preparation of inducing diuresis for treating stranguria syndrome Chinese medicine dry suspending agent
Formula:
10 parts of Folium Baeckeaes
20 parts of Herba Plantaginiss
30 parts of Herba Lysimachiaes
15 parts of Medulla Tetrapanaciss
The preparation method of dry outstanding agent is: by weight dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae and Medulla Tetrapanacis being pulverized is 100 order coarse powder, the pure water that adds 2-6 doubly to measure, decoct 20-40 minute, be naturally cooled to 20-45 ℃, remove filtering residue, filter, obtain filtrate, concentrating under reduced pressure obtains the extractum that density is 1.13-1.14, the dry fine grained that to obtain of spraying, after adding dextrin, food starch, be crushed to 200-400 order, vacuum packaging and get final product.
embodiment 5: the preparation of inducing diuresis for treating stranguria syndrome liquor
6 parts of Folium Baeckeaes
17 parts of Herba Plantaginiss
28 parts of Herba Lysimachiaes
13 parts of Medulla Tetrapanaciss
The preparation method of liquor is: by weight dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae and Medulla Tetrapanacis being pulverized is 100 order coarse powder, and the pure water that adds 2-6 doubly to measure decocts 20-40 minute, is naturally cooled to 20-45 ℃, filter, obtain filtrate, add antiseptic, sterilization, after sterilization, vacuum packaging and get final product.
embodiment 5: clinical therapeutic efficacy
The inducing diuresis for treating stranguria syndrome Chinese medicine preparation that 2010-2013 inventor develops the present invention is treated 1098 patients, male patient's 766 examples wherein, female patient's 332 examples, minimum patient 8 years old, maximum patient 75 years old, each age group patient situation is 8-18 year 211 examples, 18-25 year 129 examples, 25-35 year 453 examples, 35-45 year patient's 98 examples, 45-55 year patient's 82 examples, 55 years old above patient's 55 examples, according to the cause of disease, can be divided into: patients of urinary tract infection 433 examples, lithangiuria 109 examples, nephrotic's 556 examples, through treatment, have 1023 patients and obtained thorough radical cure, 1089 patients have positive effect, total effective rate reaches 99.18%.Through taking after inducing diuresis for treating stranguria syndrome preparation of the present invention, all have no side effect, all-ages, and effect is remarkable, be embodied in: take and can play positive effect in latter 15 days, within 45 days, can effectively improve, continue to take after 60-90 days, can thoroughly effect a radical cure, relapse rate is low.
Case 1:
A surname certain, Zhengzhou, henan people, man, 28 years old, be engaged in pesticidal preparations R&D work, contact with pesticide chemical product for a long time, wherein is no lack of high malicious product, as Bayer 71628, thimet, Aldicarb etc., feel the second half year in 2011 dysurea, removing examination in hospital is urinary tract infection, through having Western medicine treatment, curative effect is very micro-, long-term dysurea finally develops into oliguria, every day urine amount seldom, there is urine to suppress sense, do not want again the treatment of having an operation, such life allows his endurable, duty is poor, hear after inducing diuresis for treating stranguria syndrome medicament of the present invention, bought immediately the capsule preparations of this invention, after starting to take, by 3.0 grams/times of meterings, every day 3 times, take continuously after 10 days, dysurea sense obviously alleviates, continue to take after 20 days, urinary tract is unobstructed, after continue to strengthen again and treated 45 days, urine amount reaches 1.0-2.3L every day, recover normal.
Case 2:
Grandson, female, 37 years old, oneself be owner of a private enterprise, be engaged in hardware products operation, be diagnosed as urinary stone in April, 2012, symptom is dysurea, can not urinate, and calculus amount is large, after laser therapy, recurrence after month again, takes liquor of the present invention immediately, take continuously after 5 days, dysurea sense disappears, and takes continuously after 30 days, on inspection, calculus has been eliminated, later recurrence never again.
Case 3:
Zhang, man, 65 years old, these administrative affairs of village agriculture, continuous work all the year round, detected nephritis in 2010, felt at that time frequent urination at night, frequent micturition, will go to lavatory an evening 5-10 time, developed into afterwards oliguria, can not urinate, and goes after examination in hospital, take western medicine, do not feel any better, take powder of the present invention, each serving with 1 gram, every day 3 times, one after each meal, takes after 20 days continuously, nephritis, every day, urine amount returned to normal person's standard, and symptom obviously alleviates.
Case 4:
Jiang, 33 years old, be engaged in marine product sale, in 2012 annual tests, found urinary tract infection, symptom is oliguria, and every day, urine amount only had 500mL, and has urine to suppress sense, takes capsule of the present invention, after 15 days, take a favorable turn, within 30 days, recover afterwards normal, consolidate and take 30 days again, no longer recurrence.
Case 5:
Appoint certain, female, 54 years old, in the Wuming County of Nanning, build people, manage Yi Ge chop house, renal calculus has been suffered from fatigue all the year round, urinate unable, urine is suppressed, oliguria, go Wuming County institute of traditional Chinese medicine therapeutic effect poor, after one month, take Liniaotonglin capsule of the present invention, take after 7 days, take an evident turn for the better, continue to take after 30 days, recover normal.
Case 6:
Wei, man, 42 years old, people from Nanning City, Guangxi province, manages dish menu in food market, work as getting in stocks morning every day, within one day, sell goods, fatigue year after year allows him suffer from chronic nephritis, and symptom has shank edema, weak all over, urine retention, frequent urination at night, urine amount is few, take after Liniaotonglin capsule of the present invention 3 months, recover normal.
Case 7:
Song, man, 67 years old, people from Guigang, Guangxi province, cane planting rich and influential family, works for many years, allow it suffer from chronic renal insufficiency, shank edema, waist does not feel like oneself, and urine amount is few, after half a year, develop into anuria, the Hai Kun Sheng Xi Capsule that has Western medicine, curative effect is very micro-, takes immediately Liniaotonglin capsule after 3 months, sensation waist is comfortable, shank edema is disappeared, and continues to take after 2 months, and urine amount is increased to 1.0-1.5L every day, old man Song continues to take this product 1 year, it is normal that urine amount is recovered, and goes to hospital to detect, and finds that chronic renal insufficiency has obtained effective control.
Case 8:
Permitted certain, female 39 years old, is engaged in business administration work, and obtains urinary tract infection in 2011, and oliguria is urinated unablely, takes after liquor of the present invention 30 days, feels to be clearly better, and continues to take after 15 days, recovers normal, and there is no any discomfort sense, has no side effect.
Case 9:
Agriculture, man 55 years old, people from Liuzhou city, Guangxi province, Professional drivers, driver's work all the year round, day and night puts upside down, and diet is irregular, suppresses urine and allows it obtain chronic prostatitis, early stage, symptom was that waist does not feel well, and nocturia is frequent, and urine amount is few, dripping urination, take after dry suspending agent of the present invention 20 days, feel that waist is happy, without distending pain sense, continue to take after 40 days, sensation urine amount increases to some extent, and there is no above symptom, continue to take after 90 days, recover normal, and not recurrence.
Claims (9)
1. a Chinese medicine preparation for inducing diuresis for treating stranguria syndrome, is made by the raw material of following parts by weight: Folium Baeckeae 5-10 part, Herba Plantaginis 10-20 part, Herba Lysimachiae 20-30 part, Medulla Tetrapanacis 5-15 part;
The Chinese medicine preparation of described inducing diuresis for treating stranguria syndrome is powder, granule, capsule, liquor, dry outstanding agent or other pharmaceutically useful exterior-applied formulation.
2. the Chinese medicine preparation of inducing diuresis for treating stranguria syndrome according to claim 1, is characterized in that: the raw material by following parts by weight is made: Folium Baeckeae 6-8 part, Herba Plantaginis 12-18 part, Herba Lysimachiae 22-28 part, Medulla Tetrapanacis 8-12 part.
3. the Chinese medicine preparation of inducing diuresis for treating stranguria syndrome according to claim 1, is characterized in that: the raw material by following parts by weight is made: 7 parts of Folium Baeckeaes, 15 parts of Herba Plantaginiss, 25 parts of Herba Lysimachiaes, 10 parts of Medulla Tetrapanaciss.
4. the Chinese medicine preparation of inducing diuresis for treating stranguria syndrome according to claim 1, it is characterized in that: the preparation method of described powder is: by weight by dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae, Medulla Tetrapanacis coarse pulverization, be crushed to again below 100 orders, then with plastic bag vacuum packing, obtain powder.
5. the Chinese medicine preparation of inducing diuresis for treating stranguria syndrome according to claim 1, it is characterized in that: the preparation method of described granule is: by weight dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae and Medulla Tetrapanacis powder are broken to 100 order coarse powder, add appropriate dextrin, PEG400 and appropriate amount of purified water, extruding or mist projection granulating, with opaque plastics bottle evacuation, pack, obtain granule.
6. the Chinese medicine preparation of inducing diuresis for treating stranguria syndrome according to claim 1, is characterized in that: the preparation method of described capsule has two kinds:
A, described powder is pressed to method preparation described in claims 4, standby; Take edible Gelatinum oxhide, guar gum, glycerol, sodium alginate and pure water as rubber raw material, through changing glue, mixing the acquisition glue that heats up, then powder and glue are carried out to pelleting, setting, dry, packing, obtains;
B, will be by weight dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae and Medulla Tetrapanacis to be pulverized be 100 order coarse powder, and the pure water that adds 2-6 doubly to measure, decocts 20-40 minute, naturally be cooled to 20-45 ℃, filter, obtain filtrate, concentrating under reduced pressure, the density concentrated solution that is 1.12-1.15, concentrated solution is mixed to pelleting, setting, dry with the glue that step a makes, packing, obtains.
7. the Chinese medicine preparation of inducing diuresis for treating stranguria syndrome according to claim 1, it is characterized in that: the preparation method of described liquor is: by weight dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae and Medulla Tetrapanacis being pulverized is 100 order coarse powder, the pure water that adds 2-6 doubly to measure, decocts 20-40 minute, is naturally cooled to 20-45 ℃, filter, obtain filtrate, add antiseptic, sterilization, after sterilization, vacuum packaging and get final product.
8. the Chinese medicine preparation of inducing diuresis for treating stranguria syndrome according to claim 1, it is characterized in that: the preparation method of described dry outstanding agent is: by weight dry Folium Baeckeae, Herba Plantaginis, Herba Lysimachiae and Medulla Tetrapanacis being pulverized is 100 order coarse powder, the pure water that adds 2-6 doubly to measure, decoct 20-40 minute, naturally be cooled to 20-45 ℃, remove filtering residue, filter, obtain filtrate, concentrating under reduced pressure obtains the extractum that density is 1.12-1.15, the dry fine grained that to obtain of spraying, is crushed to 200-400 order after adding dextrin, food starch, vacuum packaging and get final product.
9. the Chinese medicine preparation of inducing diuresis for treating stranguria syndrome claimed in claim 1, is characterized in that: the Chinese medicine preparation of producing is used for the treatment of lithangiuria, cystitis, urinary tract infection, urgent micturition frequent micturition, chronic nephritis, renal calculus.
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| CN104306737A (en) * | 2014-11-09 | 2015-01-28 | 朱海燕 | Traditional Chinese medicine composition for treating kidney calculi as well as preparation method and application thereof |
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Non-Patent Citations (2)
| Title |
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| 刘彬编著: "《百草良方》", 31 August 2007, article "岗松/车前草", pages: 174-175 * |
| 李志文主编: "《妇科病常用对药》", 30 November 2012, article "车前草/通草/金钱草", pages: 219-222 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104306737A (en) * | 2014-11-09 | 2015-01-28 | 朱海燕 | Traditional Chinese medicine composition for treating kidney calculi as well as preparation method and application thereof |
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