CN102631481B - Chinese medicinal preparation for treating viral hepatitis - Google Patents
Chinese medicinal preparation for treating viral hepatitis Download PDFInfo
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- CN102631481B CN102631481B CN2012101545961A CN201210154596A CN102631481B CN 102631481 B CN102631481 B CN 102631481B CN 2012101545961 A CN2012101545961 A CN 2012101545961A CN 201210154596 A CN201210154596 A CN 201210154596A CN 102631481 B CN102631481 B CN 102631481B
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a Chinese medicinal preparation for treating viral hepatitis, which is prepared through years of repeated verifications in clinical tests, and is in accordance with the traditional Chinese medicine. The Chinese medicinal preparation comprises gold cypress, rheum officinale, red peony root, teasel root, selfheal spike, costustoot, gentian, artemisia capillaries, abrus herb, fructus toosendan, golden thread, Chinese dodder seed, peach kernel, bidentate achyranthes root, 20 to 40 parts of fennel, lotus plumule, peony, prepared rehmannia, ganoderma lucidum, Chinese brake herb, bunge corydalis herb, fingered citron, stone-like omphalia and sea-ear shell. The preparation is prepared by the following steps: soaking, crushing and extracting to separate required components; and compounding to prepare medicaments, tablets, capsules and the like. According to the Chinese medicinal preparation, the liver is subjected to deficiency and excess regulation and regulating and tonifying combination based on both principal and secondary aspect of disease treatment, and anti-inflammatory compatibility is assisted, so that the viral hepatitis is healed.
Description
Technical field
The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine preparation for the treatment of viral hepatitis.
Background technology
Viral hepatitis be by several different have a liking for that hepatovirus (hepatitis virus) causes based on the liver inflammation for a long time with one group of infectious disease of downright bad pathological changes, be legal Category B notifiable disease, have that infectiousness is strong, characteristics such as complicated, popular wide general, the sickness rate height in route of transmission; Part is B-mode, third type and hepatitis D patient can develop into chronicly, and can develop into liver cirrhosis and primary hepatoma, and is very big to people ' s health harm.At present fixed have five types of first type, B-mode, third type, fourth type and hepatitis E, wherein first type and hepatitis E mainly show as the B-mode third type hepatitis D of acute hepatitis and can be the performance of acute hepatitis or chronic hepatitis, and the possibility that develops into liver cirrhosis and hepatocarcinoma is arranged.
Clinically, some are non-has a liking for hepatovirus such as clinically big and small, though some non-ly have a liking for hepatovirus such as infection such as cytomegalovirus, Epstein-Barr virus also can cause hepatic injury, does not belong to viral hepatitis; Once hepatitis G virus of being discussed warmly (HGV) and menses transmitted virus (TTV) was pathogenic still disputable, but thought now not belong to and have a liking for hepatovirus.
Viral hepatitis is a popular disease in the world wide, be characteristics with hepatocellular degeneration, necrosis, inflammatory reaction on the pathology, clinical serves as main performance to feel sick, vomit, to detest oil, weak, loss of appetite, hepatomegaly, abnormal liver function, jaundice can appear in part patient, can also show as symptomless infection or self limiting inapparent infection, some patient also can show as chronic hepatitis or liver failure.Dissimilar viral hepatitis routes of transmission are not quite similar, mainly propagate as hepatitis A and hepatitis E by digestive tract (excrement-mouth approach), virus by contaminated food or/and the water source cause popular on a large scale, once in 1988 because the edible Scapharca subcrenata of viral pollution that is subjected to caused in Shanghai that maximum since the establishment of the nation hepatitis A was popular; Because contaminated water source, it is popular to break out hepatitis E in JIUYUE, 1986 to 1988 China's southern Xinjiang in year April.B-mode, third type and hepatitis D are by blood, body fluid approach and mother and baby's vertical transmission, statistical data in 2006 shows that China 1-59 year crowd hepatitis B surface antigen carrying rate is 7.18%, popular area in belonging to, among the older patient, mainly obtain to infect by mother-to-baby transmission, along with the enforcement of hepatitis B planned immunization, the mother-to-baby transmission rate obviously descends, and the HBsAg carrying rate of child below 5 years old only is 0.96%; China's general crowd's antibody to hepatitis C recall rate is 3.2%, propagate by blood transfusion or blood product, but the propagation that causes by IDU is in recent years paid much attention to; Hepatitis D is just can take place on the basis of hepatitis B, and the hepatitis D virus antibody positive rate is about 2% among the positive crowd of China HBsAG.
Physician of all times has created the medicine of a large amount of treatment viral hepatitis in continuous exploration, and most medicines all are " curing the symptoms, not the disease ".Some medicines also are easy to generate drug resistance, and patient just can keep curative effect using certain medicine article kind of just must changing dressings after reaching certain hour, and some effective prescriptions can only be because of human side, and often the cause of disease is not to the ill and poor effect.
Summary of the invention
The present invention provides a kind of Chinese medicine preparation for the treatment of viral hepatitis in order to solve the deficiencies in the prior art part.
A kind of Chinese medicine preparation for the treatment of viral hepatitis of the present invention forms by clinic tests and repeated verification for many years configuration, meets the theory of Chinese medicine.Prescription is to be raw material with the Chinese herbal medicine, isolates required composition through immersion, pulverizing and extraction etc., makes medicament, tablet, capsule etc. again after composite.The present invention carries out deficiency and excess to liver and transfers and transfer the benefit combination mutually from treating both the principal and secondary aspects of a disease, auxiliary special antiinflammatory compatibility, thus viral hepatitis is cured.
A kind of Chinese medicine preparation for the treatment of viral hepatitis is to be made by following weight portion raw material:
Cortex Phellodendri 40-60 part, Radix Et Rhizoma Rhei 40-60 part, Radix Paeoniae Rubra 40-60 part, Radix Dipsaci 40-60 part, Spica Prunellae 40-60 part, Radix Aucklandiae 40-60 part, Radix Gentianae 30-50 part, Herba Artemisiae Scopariae 30-50 part, Herba Abri 30-50 part, Fructus Toosendan 30-50 part, Rhizoma Coptidis 30-50 part, Semen Cuscutae 30-50 part, Semen Persicae 20-40 part, Radix Achyranthis Bidentatae 20-40 part, Fructus Foeniculi 20-40 part, Plumula Nelumbinis 20-40 part, Flos Moutan 20-40 part, Radix Rehmanniae Preparata 20-40 part, Ganoderma 10-30 part, Herba Pteridis Multifidae 10-30 part, Herba Violae 10-30 part, Fructus Citri Sarcodactylis 10-30 part, Omphalia 10-30 part, Concha Haliotidis 10-30 part;
Preparation method:
1, it is standby Omphalia clean → to be dried → be crushed to 300-400 order fine powder by formula proportion;
2, by formula proportion surplus stock was added qdx water logging bubble 40-60 minute, decocted 1-2 hour, after the filtrate, the medicinal residues water gaging that doubles was fried in shallow oil 15 minutes, and the filtrate waste with twice filtrate collecting decoction, is evaporated to thick paste;
3, will concentrate and add standby fine powder mixing after thick paste oven dry is crushed to 300-400 order fine powder, it is encapsulated seal after 72 hours branch.
A kind of Chinese medicine preparation for the treatment of viral hepatitis is to be made by following weight portion raw material:
Cortex Phellodendri 42-58 part, Radix Et Rhizoma Rhei 42-58 part, Radix Paeoniae Rubra 42-58 part, Radix Dipsaci 42-58 part, Spica Prunellae 42-58 part, Radix Aucklandiae 42-58 part, Radix Gentianae 32-48 part, Herba Artemisiae Scopariae 32-48 part, Herba Abri 32-48 part, Fructus Toosendan 32-48 part, Rhizoma Coptidis 32-48 part, Semen Cuscutae 32-48 part, Semen Persicae 22-38 part, Radix Achyranthis Bidentatae 22-38 part, Fructus Foeniculi 22-38 part, Plumula Nelumbinis 22-38 part, Flos Moutan 22-38 part, Radix Rehmanniae Preparata 22-38 part, Ganoderma 12-28 part, Herba Pteridis Multifidae 12-28 part, Herba Violae 12-28 part, Fructus Citri Sarcodactylis 12-28 part, Omphalia 12-28 part, Concha Haliotidis 12-28 part.
A kind of Chinese medicine preparation for the treatment of viral hepatitis is to be made by following weight portion raw material:
50 parts of Cortex Phellodendris, 50 parts of Radix Et Rhizoma Rhei, 50 parts of Radix Paeoniae Rubras, 50 parts of Radix Dipsacis, 50 parts of Spica Prunellaes, 50 parts of the Radix Aucklandiae, 40 parts of Radix Gentianaes, 40 parts of Herba Artemisiae Scopariae, 40 parts of Herba Abris, 40 parts of Fructus Toosendans, 40 parts of Rhizoma Coptidis, 40 parts of Semen Cuscutae, 30 parts in Semen Persicae, 30 parts of Radix Achyranthis Bidentataes, 30 parts in Fructus Foeniculi, 30 parts of Plumula Nelumbiniss, 30 parts of Flos Moutaies, 30 parts of Radix Rehmanniae Preparata, 20 parts of Ganodermas, 20 parts of Herba Pteridis Multifidaes, 20 parts of Herba Violaes, 20 parts of Fructus Citri Sarcodactylis, 20 parts of Omphalias, 20 parts of Concha Haliotidis.
The herbal pharmacology and the property of medicine that the present invention relates to are as follows:
Cortex Phellodendri:
[meridian distribution of property and flavor] hardship, cold.Return kidney, urinary bladder channel.
[function cures mainly] heat clearing and damp drying, pathogenic fire purging are removed and are steamed, and skin ulcer is treated in detoxifcation.Be used for damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity { is warded off }, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.The stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.Be used for hyperactivity of fire caused by deficiency of YIN, the night sweat hectic fever due to YIN-deficiency.
Radix Et Rhizoma Rhei:
[meridian distribution of property and flavor] bitter in the mouth, cold; Return spleen, stomach, large intestine, liver, pericardium channel.
[function cures mainly] purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.Be used for the excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, heat in blood is told nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.Be used for the conjunctival congestion pharyngeal swelling, gums is swollen.Radix Et Rhizoma Rhei rushes down exerts oneself to delay eliminating fire and detoxication.Be used for pathogenic fire,toxin and furuncles.The hemostasis of charred Radix Et Rhizoma Rhei cooling blood and removing stasis.Be used for heat in blood stasis of blood hemorrhage is arranged.
Radix Paeoniae Rubra:
[meridian distribution of property and flavor] bitter in the mouth is slightly cold, and returns Liver Channel.
[function cures mainly] clearing away heat and cooling blood, eliminating stasis to stop pain.Be used for maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen stomachache, injury from falling down, carbuncle skin infection.
Radix Dipsaci:
[meridian distribution of property and flavor] bitter in the mouth, suffering, tepor is returned liver, kidney channel.
[function cures mainly] invigorating the liver and kidney, bone and muscle strengthening, continuous folding is hindered, and ends metrorrhagia.Be used for soreness of the waist and knees, rheumatic arthralgia, metrorrhagia, vaginal bleeding during pregnancy, injury from falling down.Prepared RADIX DIPSACI with yellow rice wine is used for rheumatic arthralgia more, injury from falling down.Prepared RADIX DIPSACI with salt solution is used for soreness of the waist and knees more." the southern regions of the Yunnan Province book on Chinese herbal medicine ": " meridians are decided in tonifying liver, bone and muscle strengthening, end through in (muscles and bones) ache, antiabortive, control the married woman leucorrhea, tissue regeneration promoting blood, removing blood stasis with potent drugs blood, the stillborn fetus that falls, the cough-relieving hemoptysis of coughing is controlled red white turbid urine.”
Spica Prunellae: acrid in the mouth, bitterness are cold, return Liver Channel, but liver heat removing and eyesight improving, dispersing swelling and dissipating binds, suppressing the hyperactive liver sun.
The Radix Aucklandiae:
[nature and flavor] are warm in nature, acrid in the mouth, hardship.
[function cures mainly] function promoting the circulation of QI to relieve pain, warming middle-JIAO for easing the stomach is applicable to the intestines and stomach stagnation of QI, stagnant caused abdominal and hypochondriac pain of chest and abdomen swelling and pain and liver and gall damp-heat and vomiting are had loose bowels, dysentery, pain in the abdomen is strict heavy, colic of cold type etc.Radix Gentianae:
[meridian distribution of property and flavor] hardship, cold.Return liver, gallbladder meridian.
[function cures mainly] heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire.Be used for jaundice due to damp-heat, swelling of the vulva pudendal pruritus, leukorrhagia, persistent erection of the penis, eczema pruritus, conjunctival congestion, deafness, hypochondriac pain, bitter taste, convulsion with spasms.
1, control calentura stomachache: Radix Gentianae 30 grams, beat salt extracting juice clothes.
2, control hematodiarrhoea: Radix Gentianae, each 15 gram of Flos Bombacis Malabarici, female dish 30 grams of red pig are decocted in water for oral dose.
3, control conjunctival congestion and swelling pain: ⑴ Radix Gentianae 15-30 gram, beat the juice clothes.⑵ Radix Gentianae 15-30 gram is spent Peng Qi grass 30 grams in vain, and YEXIAHONG 15 grams are decocted in water for oral dose.⑶ Radix Gentianae 15-30 gram, decocting, towards the brown sugar clothes, slag is beaten the mashed eye that pastes, in stay a hole.
4, control parotitis: each is an amount of for Radix Gentianae, Herba monochoriae vaginalis, beats mashedly altogether with brown sugar, pastes the affected part.
5, control women's mastalgia: each is an amount of for Radix Gentianae, Herba Taraxaci, Fructus Seu Herba Pubescentis, beats mashedly altogether, pastes the affected part.
6, controlling the skin knife injury swells and ache: Radix Gentianae is an amount of, adds Oleum Camelliae, beats mashedly, pastes the affected part.
7, control the red and swollen pyretic toxicity of sores ulceration of skin: Radix Gentianae is an amount of, with brown sugar, beats mashedly, pastes the affected part.Or add YEXIAHONG, each is an amount of for Herba pteridis vittatae, beats mashedly, pastes the affected part.
Herba Artemisiae Scopariae:
[nature and flavor] toil, cold.
1. " herbal classic ": " bitter in the mouth is flat."
2. " not Lu ": " be slightly cold, nontoxic."
3. " property of medicine opinion ": " the bitter in the mouth suffering, slightly poisonous."
4. " pearl sac ": " bitter sweet."
[return through] goes into liver, spleen, urinary bladder channel.
1. Zhang Yuansu: " go into meridian of Foot-TAI YANG."
2. " Bencao Jingshu ": " bright, lunar, the sun three warps of foot sun."
3. " book on Chinese herbal medicine is new again ": " go into liver, kidney two warps."
[function cures mainly] clearing away heat-damp and promoting diuresis.Control jaundice due to damp-heat, dysuria, pruritus due to wind pathogen skin ulcer scabies.Join Fructus Gardeniae, Radix Et Rhizoma Rhei is controlled YANG jaundice; Join Radix Aconiti Lateralis Preparata, Rhizoma Zingiberis is controlled YIN jaundice.
Herba Abri:
[nature and flavor] are sweet, bitter; Cool; Nontoxic
[return through] heart; Lung; Liver; Stomach; Kidney channel
[function cures mainly] clearing away heat-damp and promoting diuresis, eliminating stasis to stop pain.Main icterohepatitis, stomachache, rheumatic ostalgia, traumatic injury stasis of blood pain, mastalgia.
Fructus Toosendan has another name called Fructus Toosendan:
[nature and flavor] are cold in nature, bitter in the mouth,
[function] is a kind of of qi-activating drug; Mainly go into Liver Channel, the catharsis liver-heat, promoting the circulation of QI to relieve pain have except that damp and hot, clearing away liver-fire, pain relieving, parasiticidal function.But also be the important source material of making the efficient free of contamination novel plant class of no residual hazard pesticide.
Rhizoma Coptidis:
[meridian distribution of property and flavor] hardship, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.
[function cures mainly] heat clearing and damp drying, eliminating fire and detoxication.Be used for damp and hot feeling of fullness, the vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, the carbuncle furuncle is quenched one's thirst in toothache; External treatment eczema, eczema, auditory meatus is suppurated.The kind clear part of the body cavity above the diaphragm housing the heart and lungs of Rhizoma Coptidis (processed with wine) is burning hot.Be used for conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Be used for cold and heat and tie mutually, damp and hot middle resistance, feeling of fullness vomiting.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.Be used for incoordination between the liver and stomach, the vomiting acid regurgitation.
Semen Cuscutae:
[nature and flavor] Gan Xinping goes into liver, kidney channel.
[function cures mainly] the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, antiabortive.Be used for caused by liver and kidney deficiency, soreness of waist and knee joint, impotence and seminal emission, frequent urination and enuresis, two blurred visions are dark, diseases such as frequent fetal movement.
Semen Persicae:
Sweet flat, the bitter in the mouth of [meridian distribution of property and flavor] property is gone into lung, liver, large intestine channel;
[function cures mainly] has blood stasis removing and clots absorbing, moisturizes the effect of laxation; Control amenorrhea, dysmenorrhea, abdominal mass abdominal mass mass in the abdomen, traumatic injury, dryness of the intestine constipation.Effects such as Semen Persicae has antiinflammatory, sees allergy, antitumor, antitussive.
Radix Achyranthis Bidentatae:
[meridian distribution of property and flavor] bitter in the mouth, acid, flat; Return liver, kidney channel.
[function cures mainly] invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards.Be used for soreness of waist and knee joint, muscles and bones is unable, amenorrhea lump in the abdomen, dizziness due to hyperactivity of liver-YANG.
Fructus Foeniculi:
[nature and flavor] are warm in nature, acrid in the mouth; Return liver,kidney,spleen, stomach warp.
[function cures mainly] warming YANG to expel cold, regulating QI to relieve pain.Be used for colic of cold type stomachache, lumbago due to renal deficiency, gastrofrigid vomiting, coldness and pain in the epigastrium.
Plumula Nelumbinis:
[nature and flavor] hardship, cold, nontoxic;
[effect] clears away heart-fire, and reduces phlegm and internal heat hemostasis, arresting seminal emission.Control vexedly, thirsty, spit blood seminal emission, conjunctival congestion and swelling pain." book on Chinese herbal medicine is new again ": clearing away heart-fire, the suppressing the hyperactive liver fire, lung-fire falls in the purgation of spleen excess fire.The relieving restlessness of relieving summer heat, promoting the production of body fluid to quench thirst is controlled the order redness.
Flos Moutan:
Paeonia suffruticosa not only has ornamental value, but also has very high medical value.The root of Paeonia suffruticosa is processed into " Cortex Moutan ", is famous and precious Chinese herbal medicine.Its cold nature, acrid in the mouth, nontoxic, go into the heart, liver, kidney three warps, dissipating blood stasis blood is arranged, purify the blood and blood, pain relieving, the effect of stimulating the menstrual flow, bring high blood pressure down in addition, the effect of anti-inflammation, clothes can be lengthened the life by beneficial body for a long time.The regulating liver-QI that nourishes blood, is applicable to chloasma faciei at the strongly fragrant blood stasis dispelling that looses, and skin aging is often drunk the QI and blood lung of living, and appearance is ruddy, improves menoxenia, and dysmenorrhea is ended sweating due to debility, night sweat.
Radix Rehmanniae Preparata:
Sweet, the tepor of [meridian distribution of property and flavor] property is gone into liver, kidney channel.
[effect] nourishing the blood and yin, vital essence replenishing and marrow benifiting.
Ganoderma:
[nature and flavor] are sweet, and are flat, GUIXIN, lung, liver, kidney channel.
[curing mainly] asthenia, cough, asthma, insomnia, dyspepsia, malignant tumor etc.
Herba Pteridis Multifidae:
[meridian distribution of property and flavor] light, little hardship, cold.
[function cures mainly] clearing away heat-damp and promoting diuresis, the detoxifcation dysentery relieving, cooling blood for hemostasis is used for dysentery, gastroenteritis, hepatitis, urinary system infection, cat fever, laryngopharynx swelling and pain, leucorrhea, metrorrhagia, pesticide intoxication; Traumatic hemorrhage is controlled in external, burn and scald.
Herba Violae:
[meridian distribution of property and flavor] is cold in nature, bitter in the mouth, and mild toxicity is gone into the heart, spleen channel;
[function cures mainly] heat-clearing and toxic substances removing.Control epidemic febrile disease hyperpyrexia agitation, influenza, infectious hepatitis, nephritis, scrofula, parotitis, furuncle and other pyogenic infection.
Fructus Citri Sarcodactylis:
[meridian distribution of property and flavor] is hot, bitter, sour, and temperature is returned liver, spleen, lung meridian.
[function cures mainly] tonifying liver warming the stomach, preventing or arresting vomiting is told, and the cold syndrome of the stomach that disappears expectorant is controlled gastric qi pain, ends the cold painful and middle circulation of qi promoting of face.Be used for stagnation of liver-QI and stomach-QI, leukorrhagia, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, lack of appetite vomiting.
Omphalia:
[nature and flavor] hardship, cold, slightly poisonous.1. " herbal classic ": bitter in the mouth, cold.2. " not Lu ": salty, be slightly cold slightly poisonous 3. " detailed outline ": sweet little hardship, flat.4. " the medical center bun is wanted ": picric acid is salty, and is cold.
[return through] goes into stomach, large intestine channel.1. " book on Chinese herbal medicine converge with speech ": start with, sufficient Yangming Channel.2. " Thunder God is concocted the property of medicine and is separated ": go into lung, spleen, stomach three warps.3. " beautiful Chinese catalpa medicine is separated ": start with few cloudy heart, liver channel of foot-Jueyin.
[function cures mainly] removing food stagnancy, parasite killing.Control abdominal pain due to worm stagnation, infantile malnutrition, acute infantile convulsion.1. " herbal classic ": main three worms extremely, by poison, pathogenic heat in the stomach, sharp husband, unfavorable woman, the cream that rubs removes children's's all kinds of diseases and ailments.2. " not Lu ": by pathogen, aversion to wind sweating, allowance for bark middle heat, knot is long-pending, tapeworm, very little white more than from going out.3. " property of medicine opinion ": can pursue wind, main epilepsy is mad to be walked, and kills ascarid.4. " beautiful Chinese catalpa medicine is separated ": heat clearing away is soothing the liver, kills proglottid of tapeworm, and body wind removes epilepsy, ends children's's antiperspirant.5. " Shaanxi Chinese medicinal herbal ": eliminating stagnated food and killing intestinal worms, heat-clearing and toxic substances removing.Control abdominal pain due to worm stagnation, infantile malnutrition, pathogenic heat in the stomach, more remarkable to the taeniasis curative effect.
[method for making] cleaned, and dries, and pulverizes.Must not steaming and decocting or high-temperature baking.
Concha Haliotidis:
[nature and flavor] are salty, flat, nontoxic.
[curing mainly] be photophobia 1..With Concha Haliotidis, Herba Tagetis Patulae, each money of Radix Glycyrrhizae, decocting, cold back clothes.2. corneal nebula after the pox.Forged with the Concha Haliotidis naked light, and ground and be the end, and added the Flos Eriocauli five equilibrium, porphyrize can be baked Hepar Sus domestica and eat altogether.3. deficiency of the liver corneal nebula (deficiency of vital energy, blood deficiency, deficiency of the liver, one's eyes became bloodshot, night such as chicken peck, and bear cataract).With Concha Haliotidis (incinerating), Herba Equiseti Hiemalis's (roasting), be divided into the end.Whenever get two money, use decocting together, connect the slag clothes down with Rhizoma Zingiberis Recens, Fructus Jujubae.Obey every day three times.4. optic atrohic blindness, nyctalopia.With Concha Haliotidis one or two (charred medicinal herb with its property retained), add three liang of Rhizoma Atractylodis (peeling), be ground into the end.Whenever get three money, put into the Hepar Sus domestica of incision, it is fixed to prick, and it is ripe to add decocting, takes advantage of the hot smoking order, after waiting to change temperature, and food liver drink juice.5. urine stranguria.Remove rough bark with Concha Haliotidis, grind and be the end, water flies over.Every clothes two money, boiled water send down.
One day clothes secondary.In drenching, the soft or hard thing is arranged, promptly add rotten wood end five minutes.
[pharmacological action] 1. has heat clearing away, calmness, blood pressure lowering, sympatheticomimetic effect.2. anti-infectious function: the antibacterial experiment of haliotis diversicolor Reeve extracting solution (cylinder plate method) shows, and is the strongest to the inhibitory effect of staphylococcus aureus, escherichia coli, bacillus pyocyaneus.Its shell internal layer hydrolyzed solution shows that through the anti-carbon tetrachloride acute poisoning of white mice (hepatitis model) experiment administration group glutamate pyruvate transaminase obviously descends than matched group.Pathology section examination matched group hepatocyte has obvious necrosis region, and several no degeneration of administration group hepatocyte.Sheep Carnis Haliotidis juice has an anti-effect that has golden yellow suppuration staphylococcus (Staphylococcusaureus), influenza to emit virus in external.3. other work
With: haliotis diversicolor Reeve acidic extraction liquid is external to rabbit, and the influence experiment of body intravascular coagulation time shows all have significant anticoagulation (P＜0.001).Its shell extracting solution shows that to scarce ammonia experiment under the white mice normal pressure obvious oxytolerant effect is arranged; The perfusion flow of isolated mouse lung is increased, expand tracheobronchial smooth muscle (spreading rate 17%).By irritating stomach and the two kinds of approach in abdominal cavity, give white mice haliotis diversicolor Reeve water decoction-alcohol sedimentation shallow lake extracting solution after one week continuously, measure the special rosette number of spleen and show to have immunosuppressive action (P＜0.001).
Specific implementation method:
Embodiment 1, prescription:
Cortex Phellodendri 40g, Radix Et Rhizoma Rhei 40g, Radix Paeoniae Rubra 40g, Radix Dipsaci 40g, Spica Prunellae 40g, Radix Aucklandiae 40g, Radix Gentianae 30g, Herba Artemisiae Scopariae 30g, Herba Abri 30g, Fructus Toosendan 30g, Rhizoma Coptidis 30g, Semen Cuscutae 30g, Semen Persicae 20g, Radix Achyranthis Bidentatae 20g, Fructus Foeniculi 20g, Plumula Nelumbinis 20g, Flos Moutan 20g, Radix Rehmanniae Preparata 20g, Ganoderma 10g, Herba Pteridis Multifidae 10g, Herba Violae 10g, Fructus Citri Sarcodactylis 10g, Omphalia 10g, Concha Haliotidis 10g;
Preparation method:
1, it is standby Omphalia clean → to be dried → be crushed to 300-400 order fine powder by formula proportion;
2, by formula proportion surplus stock was added qdx water logging bubble 40-60 minute, decocted 1-2 hour, after the filtrate, the medicinal residues water gaging that doubles was fried in shallow oil 15 minutes, and the filtrate waste with twice filtrate collecting decoction, is evaporated to thick paste;
3, will concentrate and add standby fine powder mixing after thick paste oven dry is crushed to 300-400 order fine powder, it is encapsulated seal after 72 hours branch.
Embodiment 2, prescription:
Cortex Phellodendri 42g, Radix Et Rhizoma Rhei 42g, Radix Paeoniae Rubra 42g, Radix Dipsaci 42g, Spica Prunellae 42g, Radix Aucklandiae 42g, Radix Gentianae 32g, Herba Artemisiae Scopariae 32g, Herba Abri 32g, Fructus Toosendan 32g, Rhizoma Coptidis 32g, Semen Cuscutae 32g, Semen Persicae 22g, Radix Achyranthis Bidentatae 22g, Fructus Foeniculi 22g, Plumula Nelumbinis 22g, Flos Moutan 22g, Radix Rehmanniae Preparata 22g, Ganoderma 12g, Herba Pteridis Multifidae 12g, Herba Violae 12g, Fructus Citri Sarcodactylis 12g, Omphalia 12g, Concha Haliotidis 12g.
Preparation method is identical with embodiment 1 with usage and dosage.
Embodiment 3, prescription:
Cortex Phellodendri 50g, Radix Et Rhizoma Rhei 50g, Radix Paeoniae Rubra 50g, Radix Dipsaci 50g, Spica Prunellae 50g, Radix Aucklandiae 50g, Radix Gentianae 40g, Herba Artemisiae Scopariae 40g, Herba Abri 40g, Fructus Toosendan 40g, Rhizoma Coptidis 40g, Semen Cuscutae 40g, Semen Persicae 30g, Radix Achyranthis Bidentatae 30g, Fructus Foeniculi 30g, Plumula Nelumbinis 30g, Flos Moutan 30g, Radix Rehmanniae Preparata 30g, Ganoderma 20g, Herba Pteridis Multifidae 20g, Herba Violae 20g, Fructus Citri Sarcodactylis 20g, Omphalia 20g, Concha Haliotidis 20g.
Preparation method is identical with embodiment 1 with usage and dosage.
Embodiment 4, prescription:
Cortex Phellodendri 58g, Radix Et Rhizoma Rhei 58g, Radix Paeoniae Rubra 58g, Radix Dipsaci 58g, Spica Prunellae 58g, Radix Aucklandiae 58g, Radix Gentianae 48g, Herba Artemisiae Scopariae 48g, Herba Abri 48g, Fructus Toosendan 48g, Rhizoma Coptidis 48g, Semen Cuscutae 48g, Semen Persicae 38g, Radix Achyranthis Bidentatae 38g, Fructus Foeniculi 38g, Plumula Nelumbinis 38g, Flos Moutan 38g, Radix Rehmanniae Preparata 38g, Ganoderma 28g, Herba Pteridis Multifidae 28g, Herba Violae 28g, Fructus Citri Sarcodactylis 28g, Omphalia 28g, Concha Haliotidis 28g.
Preparation method is identical with embodiment 1 with usage and dosage.
Embodiment 5, prescription:
Cortex Phellodendri 60g, Radix Et Rhizoma Rhei 60g, Radix Paeoniae Rubra 60g, Radix Dipsaci 60g, Spica Prunellae 60g, Radix Aucklandiae 60g, Radix Gentianae 50g, Herba Artemisiae Scopariae 50g, Herba Abri 50g, Fructus Toosendan 50g, Rhizoma Coptidis 50g, Semen Cuscutae 50g, Semen Persicae 40g, Radix Achyranthis Bidentatae 40g, Fructus Foeniculi 40g, Plumula Nelumbinis 40g, Flos Moutan 40g, Radix Rehmanniae Preparata 40g, Ganoderma 30g, Herba Pteridis Multifidae 30g, Herba Violae 30g, Fructus Citri Sarcodactylis 30g, Omphalia 30g, Concha Haliotidis 30g;
Preparation method is identical with embodiment 1 with usage and dosage.
Index is checked in four of hepatic fibrosis:
Serum liver fibrosis mark mainly contains following several:
1. PCIII (III procollagen type): the III Collagen Type VI is synthetic in the reflection liver, and serum content is consistent with liver fibre degree, and obviously relevant with serum T-globulin levels.Normal value＜120ug/L.
2. IV-C (IV Collagen Type VI): be to constitute the basement membrane Main Ingredients and Appearance, the turnover rate of reflection basement membrane collagen, content increases that sensitivity reflects the fine process of liver, is one of early sign of liver fibre.Normal value＜75ug/L.
3. LN (laminin):, be proportionate with hepatic fibrosis active level and portal venous pressure for distinctive non-collagen structural protein in the basement membrane.Normal value＜130ug/ml.
4. HA (hyaluronidase): be one of matrix components, synthetic by Interstitial cell, can accurately reflect fibre weight and the hepatocyte condition in damaged that has generated in the liver delicately, there is this index of thinking more can completely reflect disease liver overall picture than the liver biopsy.
[0072]5. PLD (prolinase) is the key enzyme of collagen protein degraded, and is consistent with collagen fiber active proliferation degree in the liver, is the good index of reflection liver fiber progress.Normal value 1107 ± 19.5u/L[5] [6].
In the above-mentioned serum hepatic fibrosis index, clinical common combinations of reaching common understanding is: PCIII+PCIV+HA+LN is called four inspections of hepatic fibrosis.
A kind of 500 patient's clinical trials that viral hepatitis selects to have symptoms such as viral hepatitis for the treatment of of the present invention.Wherein, male 338 people, women 162 people take 2 days produce effects, maximum 5 all transference cures, total effective rate 96.52% shows more rate 85.96%, shows that this medicine has obvious curative effects to hepatopaths such as viral hepatitis.
Model case:
Case 1:
King x, 45 years old, take Chinese medicine preparation of the present invention, young waiter in a wineshop or an inn sun patient changes into great three positive and treat successfully, passes through and takes three courses of treatment of Chinese medicine preparation of the present invention, and inspection liver function normal virus amount is that feminine gender all is normal.
Case 2:
Thank to x, man, 34 years old.The patient began to occur diarrhoea, yellowish complexion, hepatalgia, anorexia, detests symptoms such as greasy in 2009.Diagnosis: the patient comes institute on August 5th, 2010 and checks, finds that through looking into the patient is hepatitis B great three positive (HBsAg25, HBeAg19, HBcAb+), and liver function has obvious damage, and transaminase's numerical value has all surpassed 300. and hepatalgia occurred.Through taking three courses of treatment of Chinese medicine preparation of the present invention, check that liver function normal virus amount is that feminine gender all is normal.
Case 3:
Field xx, the man, 35 years old ill virus hepatitis is after the medicine that I had never expected two courses of treatment has been obeyed, significantly felt oneself variation, in high spirits a lot, face is also ruddy, and is individual just as having changed, the inspection liver function recovery is normal, the DNA normal scope of becoming a full member, and in the time of three months, cAg is turned out cloudy.
Case 4:
Wu xx, the man, 63 years old, from March, 2009, that sb.'s illness took a turn for the worse was serious because of more than 20 years hepatitis B small three positive, hepatalgia appears, general fatigue is unable, dizzy, xerostomia, bitter taste, loss of appetite, feel sick, detest a series of symptoms such as greasy local hospital that arrives and be checked, and is the inspection of having done liver power checking and virus quantity at that time, and the doctor says at that time, the transaminase is severe overweight, and liver dysfunction is serious.Ultrasound diagnosis is liver cirrhosis period.The task of top priority is the disease controlling of hastening, and a course of treatment, it is normal that liver function and virus quantity have recovered substantially, after the medicine clothes of two courses of treatment, checks that liver function recovery is normal, the DNA normal scope of becoming a full member, and in the time of three months, cAg is turned out cloudy.
Claims (3)
1. a Chinese medicine preparation for the treatment of viral hepatitis is characterized in that, is to be made by following weight portion raw material:
Cortex Phellodendri 40-60 part, Radix Et Rhizoma Rhei 40-60 part, Radix Paeoniae Rubra 40-60 part, Radix Dipsaci 40-60 part, Spica Prunellae 40-60 part, Radix Aucklandiae 40-60 part, Radix Gentianae 30-50 part, Herba Artemisiae Scopariae 30-50 part, Herba Abri 30-50 part, Fructus Toosendan 30-50 part, Rhizoma Coptidis 30-50 part, Semen Cuscutae 30-50 part, Semen Persicae 20-40 part, Radix Achyranthis Bidentatae 20-40 part, Fructus Foeniculi 20-40 part, Plumula Nelumbinis 20-40 part, Flos Moutan 20-40 part, Radix Rehmanniae Preparata 20-40 part, Ganoderma 10-30 part, Herba Pteridis Multifidae 10-30 part, Herba Violae 10-30 part, Fructus Citri Sarcodactylis 10-30 part, Omphalia 10-30 part, Concha Haliotidis 10-30 part;
Preparation method:
It is standby Omphalia clean → to be dried → be crushed to 300-400 order fine powder by formula proportion;
By formula proportion surplus stock was added qdx water logging bubble 40-60 minute, decocted 1-2 hour, after the filtrate, the medicinal residues water gaging that doubles was fried in shallow oil 15 minutes, and the filtrate waste with twice filtrate collecting decoction, is evaporated to thick paste;
Add standby fine powder mixing with concentrating after the thick paste oven dry is crushed to 300-400 order fine powder, it is encapsulated seal after 72 hours branch.
2. a kind of Chinese medicine preparation for the treatment of viral hepatitis according to claim 1 is characterized in that, is to be made by following weight portion raw material:
Cortex Phellodendri 42-58 part, Radix Et Rhizoma Rhei 42-58 part, Radix Paeoniae Rubra 42-58 part, Radix Dipsaci 42-58 part, Spica Prunellae 42-58 part, Radix Aucklandiae 42-58 part, Radix Gentianae 32-48 part, Herba Artemisiae Scopariae 32-48 part, Herba Abri 32-48 part, Fructus Toosendan 32-48 part, Rhizoma Coptidis 32-48 part, Semen Cuscutae 32-48 part, Semen Persicae 22-38 part, Radix Achyranthis Bidentatae 22-38 part, Fructus Foeniculi 22-38 part, Plumula Nelumbinis 22-38 part, Flos Moutan 22-38 part, Radix Rehmanniae Preparata 22-38 part, Ganoderma 12-28 part, Herba Pteridis Multifidae 12-28 part, Herba Violae 12-28 part, Fructus Citri Sarcodactylis 12-28 part, Omphalia 12-28 part, Concha Haliotidis 12-28 part.
3. a kind of Chinese medicine preparation for the treatment of viral hepatitis according to claim 2 is characterized in that, is to be made by following weight portion raw material:
50 parts of Cortex Phellodendris, 50 parts of Radix Et Rhizoma Rhei, 50 parts of Radix Paeoniae Rubras, 50 parts of Radix Dipsacis, 50 parts of Spica Prunellaes, 50 parts of the Radix Aucklandiae, 40 parts of Radix Gentianaes, 40 parts of Herba Artemisiae Scopariae, 40 parts of Herba Abris, 40 parts of Fructus Toosendans, 40 parts of Rhizoma Coptidis, 40 parts of Semen Cuscutae, 30 parts in Semen Persicae, 30 parts of Radix Achyranthis Bidentataes, 30 parts in Fructus Foeniculi, 30 parts of Plumula Nelumbiniss, 30 parts of Flos Moutaies, 30 parts of Radix Rehmanniae Preparata, 20 parts of Ganodermas, 20 parts of Herba Pteridis Multifidaes, 20 parts of Herba Violaes, 20 parts of Fructus Citri Sarcodactylis, 20 parts of Omphalias, 20 parts of Concha Haliotidis.
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Non-Patent Citations (6)
| Title |
|---|
| 21世纪抗肝炎中药研究开发的机遇与挑战;肖小河等;《中国中药杂志》;20011031;第26卷(第10期);662-666 * |
| 田海河.董建华教授治疗乙型肝炎临床经验.《新中医》.1992,(第1期),1-2. |
| 祖武.试论肝炎的中医治疗.《湖南中医药导报》.1995,第1卷(第5期),26-27. |
| 肖小河等.21世纪抗肝炎中药研究开发的机遇与挑战.《中国中药杂志》.2001,第26卷(第10期),662-666. |
| 董建华教授治疗乙型肝炎临床经验;田海河;《新中医》;19921231(第1期);1-2 * |
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