CN104491753A - Detoxifying preparation for treating damp-heat toxin accumulated type cholecystitis and preparation method of detoxifying preparation - Google Patents

Detoxifying preparation for treating damp-heat toxin accumulated type cholecystitis and preparation method of detoxifying preparation Download PDF

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CN104491753A
CN104491753A CN201510013671.6A CN201510013671A CN104491753A CN 104491753 A CN104491753 A CN 104491753A CN 201510013671 A CN201510013671 A CN 201510013671A CN 104491753 A CN104491753 A CN 104491753A
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parts
fructus
damp
fine powder
toxic substances
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白忠可
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Abstract

The invention discloses a detoxifying preparation for treating damp-heat toxin accumulated type cholecystitis and a preparation method of the detoxifying preparation. The detoxifying preparation is prepared from the following main crude drugs in parts by weight: 9-16 parts of salvia chinensis, 15-30 parts of semen cuscutae, 9-16 parts of sedum sarmentosum, 20-40 parts of astragalus, 10-20 parts of wolfberries, 6-12 parts of curcuma zedoaria, 8-16 parts of medical stone, 8-16 parts of dendrobe, 7-14 parts of grifola, 9-15 parts of fructus aurantii, 12-16 parts of jasmine, 9-15 parts of liquorice, 12-24 parts of radix isatidis, 8-12 parts of hedyotis, 6-15 parts of aralia decaisneana hance and 8-16 parts of szechwan chinaberry fruits. The detoxifying preparation is high in cure rate, capable of simultaneously treating both symptoms and root causes, noninvasive, free of side effects, remarkable in curative effect, relatively low in treatment cost, free of dependence and capable of ensuring that cholecystitis does not easily recur.

Description

Damp and hotly accumulate malicious type cholecystitis removing toxic substances medicament and preparation
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to and a kind of damp and hotly accumulate malicious type cholecystitis removing toxic substances medicament and preparation.
Background technology
Cholecystitis is a kind of inflammatory lesion caused because gallbladder suffers bacterial infection or chemical irritation (bile component change), and be abdominal surgery commonly encountered diseases clinically, its sickness rate is only second to appendicitis, up to more than 10%, and in the trend risen year by year.The multiple middle age of being born in 35 ~ 55 years old of cholecystitis, wherein female patient is more than male patient.The many patients of acute cholecystitis fall ill after midnight in the greasy dinner of oil-feed, because high fat diet can make gallbladder strengthen shrinking, and flat sleeping be easy to little cholelithiasis and slip into and incarceration cystic duct.Main manifestations is right upper quadrant rest pain, paroxysmal aggravation, can take on back of the body radiation to the right; Often occur together heat, nausea and vomiting, but it is rare to shiver with cold, and jaundice is light.Abdomen examination finds that upper right abdomen is full, gallbladder area tension of abdominal muscle, obviously tenderness, rebound tenderness.Chronic cholecystitis symptom, sign are not true to type.Majority shows as bile peretinitis dyspepsia, detests greasy food, epigastrium vexed swollen, belch, scorching hot etc., is similar to Peptic Ulcers or chronic appendicitis; Sometimes because of Stone obstruction cystic duct, can be acute attack, but when calculus moves, blocks releasing, namely take a turn for the better rapidly.Body is looked into, and can there be mild tenderness or percussion pain in gallbladder area; If gallbladder hydrops, often can lay one's hand on and circular, smooth cystic mass.
Chinese medicine is thought, the reason causing primary disease has in damaged by excess of seven emotions, cold temperature discomfort, intemperance of taking food and calculus and ascarid disturbs.Its etiology and pathogenesis feature is as follows.1. stagnation of QI due to depression of the liver: disorder of emotion, depression of liver-QI, or rage impairing the liver, azulene Jiao failure, vapour lock network numbness, and send out as primary disease.2. dampness-heat in the liver and gallbladder: invade in exogenous damp, or thick greasy, the eating and drinking too much at one meal of addiction to greasy and sweet foods, cause dysfunction of the spleen in transportation, stagnation of phlegm-damp in middle-JIAO, heat resulting from stagnation of QI; Or insobriety, retention of damp-heat in the interior, makes liver and gall lose it and flows bar and reach, and send out as primary disease.3. blood stasis is at a stop: the stagnation of QI with the passing of time, thrombosis.Blood stasis stops amassing, or damp-heat blocking in the body, and the bright blood stasis of heat, causes the bile stasis of blood stagnant, and side of body network numbness hinders and sends out as primary disease.4. asthenia of both the spleen and kidney: prolonged illness or labor are for excessively, or ferritic deficiency of spleen-YANG and kidneyYANG, side of body network loses supports in wet warm moistening and sends out as primary disease.Cholecystitis typing: 1, stagnation of QI due to depression of the liver: intermittent dull pain under upper right abdomen or xiphoid-process, can involve to shoulder back pain, can have low grade fever, dry pharynx, impatient easily tired, anorexia.Light red tongue, white and thin fur or micro-Huang, stringy pulse or stringy and tense pulse.2, dampness-heat in the liver and gallbladder: right flank or epigastrium pain, tenderness, in persistence angor, paroxysmal is aggravated, the multidirectional right shoulder radiation of its pain, distension and fullness in the abdomen, the thirsty or fever with aversion to cold of fever of the body, or nausea and vomiting, indigestion and loss of appetite, has icteric sclera, yellowish body more.Tongue is partially red, yellow and greasy fur, wiry and frequent pulse.3, accumulate in scorchingly hot: the high heat of shiver with cold, right flank and epigastric pain tenderness, jaundice increases the weight of, and short urination is red, constipation, very then coma, tachypnea, cold extremities.Crimson tongue is red, dry, greasy fur or greyish black, no fur, wiry and frequent pulse or count accurately.4, deficiecny of liver-YIN: pain in the right hypochondrium, how in dull pain, the vertigo, xerostomia, deafness and tinnitus, being irritable and getting angry easily, little sleep disturbed by dreams.Red tongue or have crackle or see stripped fur, stringy and thready pulse.
Application publication number CN 103301393 A(application number 201210067663.6) Chinese patent literature disclose a kind of Chinese medicine pill for the treatment of cholecystitis, it is made up of the raw material of following weight portion: Radix Aucklandiae 90-100 part, Fructus Aurantii 90-100 part, Radix Curcumae 90-100 part, Herba Artemisiae Scopariae 120-150 part, Radix Gentianae 90-100 part, Fel Sus domestica 500-550 part.Application publication number CN 103263516 A(application number 201310209982.0) Chinese patent literature disclose a kind of medicine for the treatment of cholecystitis, it is made up of the raw material of following weight proportioning: Radix Notoginseng 10 ~ 30, Fructus Crataegi 10 ~ 20, Pericarpium Citri Reticulatae 10 ~ 25, Flos Caryophylli 10 ~ 25, Radix Bupleuri 15 ~ 35, the Radix Paeoniae Alba 15 ~ 35, Fructus Aurantii 20 ~ 35, the Radix Aucklandiae 10 ~ 20, Fructus Toosendan 10 ~ 20, Herba Artemisiae Scopariae 6 ~ 15, Herba Lysimachiae 20 ~ 35, Radix Glycyrrhizae 3 ~ 10.Application publication number CN 104147523 A(application number 201410412895.X) Chinese patent literature disclose a kind of Chinese medicine preparation being used for the treatment of cholecystitis, the crude drug chosen and composition by weight thereof be respectively: Herba Artemisiae Scopariae 20-30 gram, Radix Gentianae 10-20 gram, Radix Paeoniae Alba 10-20 gram, Folium Isatidis 10-20 gram, Herba Duchesneae Indicae 10-20 gram, Radix osterici citriodori (Radix Angelicae Citriodorae) 10-20 gram, Herba Lysimachiae 10-20 gram, Radix Curcumae 10-20 gram, Rhizoma Curcumae 8-12 gram, Semen Plantaginis 8-15 gram, Herba Centipedae 8-12 gram, Radix et Rhizoma Rhei (processed) 8-12 gram, Radix Glycyrrhizae 8-12 gram, Radix Scutellariae 8-12 gram, Radix Aucklandiae 8-12 gram, Fructus Forsythiae 8-12 gram, Flos Carthami 8-12 gram.
The current treatment for cholecystitis generally adopts the method for oral western medicine or operation, and use Western medicine easily to recur, thorough cure rate is lower, and easily produces drug resistance, and side effect is larger.There is certain risk in operative treatment, causes wound larger to health.Market has the Chinese medicine formula of a lot for the treatment of cholecystitis but mostly poor effect and price is higher.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide and a kind of damp and hotly accumulate malicious type cholecystitis removing toxic substances medicament and preparation.Cure rate of the present invention is high, treating both the principal and secondary aspects of a disease, not easily recurrence, hurtless measure, have no side effect, evident in efficacy, medical expense is lower, no dependence.
Technical scheme of the present invention is:
Damp and hot accumulate malicious type cholecystitis removing toxic substances medicament, take off the primary raw material medicine stating weight proportion and be prepared from: Herba Salviae Chinensis 9-16, Semen Cuscutae 15-30, Herba Sedi 9-16, Radix Astragali 20-40, Fructus Lycii 10-20, Rhizoma Curcumae 6-12, Maifanitum 8-16, Herba Dendrobii 8-16, Polyporus 7-14, Fructus Aurantii 9-15, Fructus Gardeniae 12-16, Radix Glycyrrhizae 9-15, Radix Isatidis 12-24, Auricled Hedyotis Herb 8-12, Aralia decaisneana Hance 6-15, Fructus Toosendan 8-16.
Damp and hot accumulate malicious type cholecystitis removing toxic substances medicament, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Herba Salviae Chinensis 12-14, Semen Cuscutae 20-24, Herba Sedi 11-15, Radix Astragali 28-31, Fructus Lycii 13-16, Rhizoma Curcumae 8-10, Maifanitum 12-14, Herba Dendrobii 10-14, Polyporus 9-12, Fructus Aurantii 11-13, Fructus Gardeniae 13-15, Radix Glycyrrhizae 11-13, Radix Isatidis 16-20, Auricled Hedyotis Herb 9-11, Aralia decaisneana Hance 8-12, Fructus Toosendan 10-13.
Damp and hot accumulate malicious type cholecystitis removing toxic substances medicament, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: Herba Salviae Chinensis 13, Semen Cuscutae 22, Herba Sedi 13, the Radix Astragali 30, Fructus Lycii 14, Rhizoma Curcumae 9, Maifanitum 13, Herba Dendrobii 12, Polyporus 11, Fructus Aurantii 12, Fructus Gardeniae 14, Radix Glycyrrhizae 12, Radix Isatidis 18, Auricled Hedyotis Herb 10, Aralia decaisneana Hance 9, Fructus Toosendan 11.
Present invention also offers and accumulate damp and hot the preparation method that malicious type cholecystitis removing toxic substances medicament makes pharmaceutically acceptable pill, decoction, granule and powder.
The preparation method of described pill is:
(1) Fructus Gardeniae is pulverized, be laid on the pallet in microwave oven, power 1KW, heat 4-9 minute (preferably heating 7 minutes), once stirred every one minute, take out, cool, be ground into fine powder, cross No. six sieves;
(2) first pot is burnt heat, evenly be sprinkled into Testa Tritici, with moderate heat heating, treat that cigarette plays input Fructus Toosendan, every 100kg Fructus Toosendan Testa Tritici 8-14kg(is every 100kg Fructus Toosendan Testa Tritici 10kg preferably), constantly stir, fry 14-26 minute (preferably frying 20 minutes), take out, sieve removes Testa Tritici, cool, be ground into fine powder, cross No. six sieves;
(3) all the other the 14 taste medical materials except Fructus Gardeniae and Fructus Toosendan are ground into fine powder respectively, cross No. six sieves;
(4) step (1), step (2) and step (3) gained fine powder are fully mixed, add water pill, the weight of obtained every ball is the weight of the preferably obtained every ball of 0.25-0.6g(is 0.4g), dry at the temperature of 50-60 DEG C (preferably dry at the temperature of 55 DEG C), make pill water content control within 8%, to obtain final product.
The preparation method of described decoction is:
(1) Fructus Gardeniae is pulverized, be laid on the pallet in microwave oven, power 1KW, heat 4-9 minute (preferably heating 7 minutes), once stirred every one minute, take out, cool, be ground into fine powder, cross No. seven sieves;
(2) first pot is burnt heat, evenly be sprinkled into Testa Tritici, with moderate heat heating, treat that cigarette plays input Fructus Toosendan, every 100kg Fructus Toosendan Testa Tritici 8-14kg(is every 100kg Fructus Toosendan Testa Tritici 10kg preferably), constantly stir, fry 14-26 minute (preferably frying 20 minutes), take out, sieve removes Testa Tritici, cool, be ground into fine powder, cross No. seven sieves;
(3) Maifanitum is put into marmite, add water, amount of water be the 2.7-4.2 of Maifanitum weight doubly (preferred amount of water is 3.5 times of Maifanitum weight), first boil follow-up giving slow fire boiling 40-60 minute (preferably first boil with intense fire and follow-uply give slow fire boiling 50 minutes) with intense fire, leach medicinal liquid;
(4) Semen Cuscutae is loaded in gauze bag, the above-mentioned marmite filling medicinal residues is put into together with all the other the 12 taste medical materials except Fructus Gardeniae, Fructus Toosendan, Maifanitum, add water, amount of water is 3.8-6.2 times (preferred amount of water is 5.0 times of the 13 taste medical material gross weights added) of the 13 taste medical material gross weights added, first boil follow-up giving slow fire boiling 30-45 minute (preferably first boil with intense fire and follow-uply give slow fire boiling 35 minutes) with intense fire, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid are merged, add step (1) and step (2) gained fine powder, to obtain final product.
The preparation method of described granule is:
(1) Fructus Gardeniae is pulverized, be laid on the pallet in microwave oven, power 1KW, heat 4-9 minute (preferably heating 7 minutes), once stirred every one minute, take out, cool, be ground into fine powder, cross No. six sieves;
(2) first pot is burnt heat, evenly be sprinkled into Testa Tritici, with moderate heat heating, treat that cigarette plays input Fructus Toosendan, every 100kg Fructus Toosendan Testa Tritici 8-14kg(is every 100kg Fructus Toosendan Testa Tritici 10kg preferably), constantly stir, fry 14-26 minute (preferably frying 20 minutes), take out, sieve removes Testa Tritici, cool, be ground into fine powder, cross No. six sieves;
(3) all the other the 14 taste medical materials except Fructus Gardeniae and Fructus Toosendan are ground into fine powder respectively, cross No. six sieves;
(4) step (1), step (2) and step (3) gained fine powder and supplementary product starch are put in container and fully mix, add water and make soft material;
(5) step (4) gained soft material is passed through 18-28 eye mesh screen (preferably step (4) gained soft material being passed through 24 eye mesh screens with fashion of extrusion) with fashion of extrusion, make uniform granule;
(6) by dry at the temperature of 58 DEG C-68 DEG C for step (5) gained granule (preferably that step (5) gained granule is dry at the temperature of 62 DEG C), the water content control of granule, within 2%, to obtain final product.
The preparation method of described powder is:
(1) Fructus Gardeniae is pulverized, be laid on the pallet in microwave oven, power 1KW, heat 4-9 minute (preferably heating 7 minutes), once stirred every one minute, take out, cool, be ground into fine powder, cross No. seven sieves;
(2) first pot is burnt heat, evenly be sprinkled into Testa Tritici, with moderate heat heating, treat that cigarette plays input Fructus Toosendan, every 100kg Fructus Toosendan Testa Tritici 8-14kg(is every 100kg Fructus Toosendan Testa Tritici 10kg preferably), constantly stir, fry 14-26 minute (preferably frying 20 minutes), take out, sieve removes Testa Tritici, cool, be ground into fine powder, cross No. seven sieves;
(3) all the other the 14 taste medical materials except Fructus Gardeniae and Fructus Toosendan are ground into fine powder respectively, cross No. seven sieves;
(4) step (1), step (2) and step (3) gained fine powder fully being mixed, by often wrapping 3 grams of subpackages, obtaining final product.
Provided by the inventionly damp and hotly accumulate malicious type cholecystitis removing toxic substances medicament efficiently, safely, have no side effect.In addition, excellent results of the present invention also shows:
1, treating both the principal and secondary aspects of a disease, cure rate are high, not easily recur;
2, hurtless measure;
3, medical expense is lower, alleviates patient economy burden;
4, no dependence;
5, have the effects such as heat-clearing and toxic substances removing, damp eliminating spleen invigorating, nourishing the liver and kidney, pathogenic fire purging relieving restlessness, promoting flow of QI and blood, mass dissipating and swelling eliminating, removing food stagnancy pain relieving, for treatment, damp and hot to accumulate malicious type cholecystitis evident in efficacy.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Herba Salviae Chinensis: base is former: be the herb of labiate Herba Salviae Chinensis.Chemical analysis: herb is containing sterol, Triterpenoid, aminoacid.Root is containing stachyose.The property of medicine: pungent, bitter, is slightly cold.Return liver, spleen channel.Function cures mainly: blood circulation promoting and blood stasis dispelling, clearing away heat-damp and promoting diuresis, mass dissipating and swelling eliminating.Main menoxenia, dysmenorrhea, amenorrhea, metrorrhagia, has blood in stool, jaundice due to damp-heat, hot toxic-heat and blood stasis, drenches pain, leukorrhagia, rheumatic ostalgia, scrofula, and skin ulcer swells, acute mastitis, herpes zoster, leprosy, and traumatic injury wound is swollen.
Semen Cuscutae: base is former: be the dry mature seed of convolvulus cuscuta plant.The property of medicine: sweet, temperature.Return liver,kidney,spleen warp.Function cures mainly: nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.For impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen is suffered from a deficiency of the kidney and is rushed down, externally treating leucoderma.
Herba Sedi: base is former: be the herb of crassulaceae plants Herba Sedi.The property of medicine: sweet, light, cool, acid.Return liver, gallbladder, small intestine meridian.Function cures mainly: clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Main jaundice due to damp-heat, gonorrhea, dysentery, lung abscess, acute appendicitis, furuncle toxic swelling, snake bite and insect sting, burn due to hot liquid or fire, laryngopharynx swelling and pain, oral ulcer and eczema, herpes zoster.
The Radix Astragali: base is former: be the dry root of leguminous plant Radix Astagali or Radix Astragali.The property of medicine: sweet, temperature.Return lung, spleen channel.Function cures mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst, chronic nephritis proteinuria, diabetes.
Fructus Lycii: base is former: be the mature fruit of matrimony vine of solanaceae plant or lycium barbarum.The property of medicine: sweet, flat.Return liver, kidney channel.Function cures mainly: nourishing kidney, lung moistening, tonifying liver, improving eyesight.Control hepatic and renal YIN deficiency, soreness of the waist and knees, dizzy, dizzy, the many tear of blurred vision, cough due to consumptive disease, quenches one's thirst, seminal emission.
Rhizoma Curcumae: base is former: be the rhizome of zingiberaceous plant Rhizoma Curcumae, Guangxi zedoary and RADIX CURCUMAE.The property of medicine: pungent, bitter, temperature.Return liver, spleen channel.Function cures mainly: circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.Main vim and vigour are pained, eating accumulation, abdominal distention, amenorrhea due to stagnation of blood, dysmenorrhea, lump in the abdomen tumor mass in the abdomen, traumatic injury.
Maifanitum: base is former: be Acid-intermediate igneous rock rocks beschtauite.Composition: Maifanitum main component has silicon dioxide, aluminium oxide, ferrum oxide, ferrous oxide, magnesium oxide, calcium oxide, sodium oxide, potassium oxide, titanium dioxide, phosphorus pentoxide, manganese oxide, carbon dioxide, and the trace element such as fluorine, sulfur, strontium, barium, copper, zinc.The property of medicine: " detailed outline ": " sweet, temperature, nontoxic." function cures mainly: removing toxic substances and promoting granulation, damp eliminating spleen invigorating.Cure mainly carbuncle carbuncle on the back, acne, eczema, beriberi, miliaria, finger is chapped, chloasma, toothache, oral ulcer, rheumatic arthralgia, lumbago and backache, chronic hepatitis, gastritis, dysentery, diabetes, neurasthenia, wound is red and swollen, hypertension, senile sclerosis of blood vessels, tumor, lithangiuria.Generally make health product.Compatibility and incompatibility of drugs: superfine end need be ground during external application, otherwise easily cause pain.
Herba Dendrobii: base is former: be the stem of orchid Dendrobium nobile or its multiple congener.Chemical analysis: Dendrobium nobile contains dendrobine, dendramine, Herba Dendrobii time alkali, dendroxine, dendrine, 6-hydroxydendroxine, still mucous matter, starch.Dendrobium moniliformeSweet is containing dendrobine, dendramine and N-methyl dendrobine (quaternary ammonium salt).Sieve river Herba Dendrobii is containing shihunine.The property of medicine: sweet, light, micro-salty, cold.Return stomach, lung, kidney channel.Function cures mainly: promote the production of body fluid stomach reinforcing, clearing away heat and nourishing YIN.Control consumption of body fluid caused by febrile disease, xerostomia excessive thirst, after being ill deficiency-heat, it is dark that the moon hinders order.
Polyporus: base is former: be On Polyporaceae Polyporus dry sclerotia.The property of medicine: sweet, light, flat.Return kidney, urinary bladder channel.Function cures mainly: promoting diuresis to eliminate damp pathogen.For dysuria, edema, has loose bowels, stranguria with turbid discharge, leukorrhagia.
Fructus Aurantii: base is former: be the mellow fruit nearly such as rutaceae Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus), Citrus aurantium Linn., fragrant circle or Citrus aurantium L. var. amara Engl..The property of medicine: bitter, sour, is slightly cold.Return lung, spleen, liver, stomach, large intestine channel.Function cures mainly: dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.
Fructus Gardeniae: base is former: be the dry mature fruit of Maguireothamnus speciosus Fructus Gardeniae.The property of medicine: bitter, cold.GUIXIN, lung, tri-jiao channel.Function cures mainly: pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, yellow cellulitis dark coloured urine, blood strangury and dry pain, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles, external treatment bruise pain.
Radix Glycyrrhizae: base is former: be the dry root and rhizome of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..The property of medicine: sweet, flat.GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of institute's abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Radix Isatidis: base is former: be the dry root of cruciferae isatis.The property of medicine: bitter, cold.GUIXIN, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving.For maculae caused by violent heat pathogen, crimson tongue is purple dark, mumps, sore throat, scarlet fever, major part pestilence, erysipelas, carbuncle.
Auricled Hedyotis Herb: base is former: be the herb of Maguireothamnus speciosus Auricled Hedyotis Herb.Chemical analysis: herb contains cupreol, hydrocarbon, hedyotine.The property of medicine: bitter, cool.Function cures mainly: heat-clearing and toxic substances removing, and removing heat from blood is subsided a swelling.Main cold, fever, cough due to lung-heat, laryngopharynx swelling and pain, enteritis, dysentery, bleeding hemorrhoids, metrorrhagia, venom, mastitis, carbuncle furuncle and phyma poison, eczema, traumatic injury.
Aralia decaisneana Hance: base is former: be the root of Araliaceae Aralia decaisneana Hance.The property of medicine: bitter, pungent, flat.Function cures mainly: expelling wind and removing dampness, promoting blood circulation to restore menstrual flow, removing toxic substances and promoting subsidence of swelling.The hot headache due to common cold of main air, cough, rheumatic arthralgia, waist and leg ache, jaundice due to damp-heat, edema, stranguria with turbid discharge, leukorrhagia, amenorrhea, puerperal exposure to wind pain, treating swelling and pain by traumatic injury, gastric abscess, laryngopharynx swelling and pain, gingival swelling and pain.
Fructus Toosendan: base is former: be the fruit of canella Fructus Toosendan.Chemical analysis: containing Toosendanin, alkaloid, kaempferol, resin, tannin.The property of medicine: bitter, cold, poisonous.Return liver, stomach, small intestine meridian.Function cures mainly: except damp and hot, clearing away liver-fire, pain relieving, parasite killing.Control epigastric pain with cold limbs due to adverseness of heat, hypochondriac pain, colic, abdominal pain due to worm stagnation.
embodiment 1damp and hotly accumulate malicious type cholecystitis removing toxic substances medicament, the primary raw material medicine getting following weight parts is prepared from (every part for 40g): Herba Salviae Chinensis 9 parts, Semen Cuscutae 15 parts, Herba Sedi 9 parts, the Radix Astragali 20 parts, Fructus Lycii 10 parts, Rhizoma Curcumae 6 parts, Maifanitum 8 parts, Herba Dendrobii 8 parts, Polyporus 7 parts, Fructus Aurantii 9 parts, Fructus Gardeniae 12 parts, 9 parts, Radix Glycyrrhizae, Radix Isatidis 12 parts, Auricled Hedyotis Herb 8 parts, Aralia decaisneana Hance 6 parts, Fructus Toosendan 8 parts.
Above-mentioned damp and hot preparation method of accumulateing malicious type cholecystitis removing toxic substances medicament decoction is:
(1) Fructus Gardeniae is pulverized, be laid on the pallet in microwave oven, power 1KW, heat 4 minutes, once stirred every one minute, take out, cool, be ground into fine powder, cross No. seven sieves;
(2) first pot is burnt heat, be evenly sprinkled into Testa Tritici, with moderate heat heating, treat that cigarette plays input Fructus Toosendan, every 100kg Fructus Toosendan Testa Tritici 8kg, constantly stirs, and fries 14 minutes, takes out, and sieve removes Testa Tritici, cools, is ground into fine powder, crosses No. seven sieves;
(3) Maifanitum is put into marmite, add water, amount of water is 2.7 times of Maifanitum weight, first boils with intense fire and follow-uply gives slow fire boiling 40 minutes, leach medicinal liquid;
(4) Semen Cuscutae is loaded in gauze bag, put into the above-mentioned marmite filling medicinal residues together with all the other the 12 taste medical materials except Fructus Gardeniae, Fructus Toosendan, Maifanitum, add water, amount of water is 3.8 times of the 13 taste medical material gross weights added, first boil with intense fire and follow-uply give slow fire boiling 30 minutes, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid are merged, add step (1) and step (2) gained fine powder, to obtain final product.
The damp and hot using method of accumulateing malicious type cholecystitis removing toxic substances medicament decoction of the present invention: oral, every day twice (warm), each 230mL 7 days is a course for the treatment of.
embodiment 2damp and hotly accumulate malicious type cholecystitis removing toxic substances medicament, the primary raw material medicine getting following weight parts is prepared from (every part for 40g): Herba Salviae Chinensis 16 parts, Semen Cuscutae 30 parts, Herba Sedi 16 parts, the Radix Astragali 40 parts, Fructus Lycii 20 parts, Rhizoma Curcumae 12 parts, Maifanitum 16 parts, Herba Dendrobii 16 parts, Polyporus 14 parts, Fructus Aurantii 15 parts, Fructus Gardeniae 16 parts, 15 parts, Radix Glycyrrhizae, Radix Isatidis 24 parts, Auricled Hedyotis Herb 12 parts, Aralia decaisneana Hance 15 parts, Fructus Toosendan 16 parts.
Above-mentioned damp and hot preparation method of accumulateing malicious type cholecystitis removing toxic substances medicament pill is:
(1) Fructus Gardeniae is pulverized, be laid on the pallet in microwave oven, power 1KW, heat 7 minutes, once stirred every one minute, take out, cool, be ground into fine powder, cross No. six sieves;
(2) first pot is burnt heat, be evenly sprinkled into Testa Tritici, with moderate heat heating, treat that cigarette plays input Fructus Toosendan, every 100kg Fructus Toosendan Testa Tritici 10kg, constantly stirs, and fries 20 minutes, takes out, and sieve removes Testa Tritici, cools, is ground into fine powder, crosses No. six sieves;
(3) all the other the 14 taste medical materials except Fructus Gardeniae and Fructus Toosendan are ground into fine powder respectively, cross No. six sieves;
(4) step (1), step (2) and step (3) gained fine powder are fully mixed, add water pill, the weight of obtained every ball is 0.4g, dry at the temperature of 55 DEG C, makes pill water content control within 8%, to obtain final product.
model case one:xXX, female, 57 years old.Right flank continues dull pain 2 years, examines as cholecystitis through ultrasonic.Multi-treatment is invalid.Closely gradually weigh over the past half year, right flank contraction is anxious and bitterly, anorexia is greasy, generate heat fear of cold, indigestion and loss of appetite, nausea vomiting, bitter taste in the mouth and dry throat, yellowish fur, stringy and tense pulse uncomfortable in chest.Examine and see upper right abdomen mild tenderness, pale tongue with white fur, deep-slow pulse.Card accumulates poison for damp and hot.Use the present embodiment gained is damp and hot accumulates malicious type cholecystitis removing toxic substances medicament pill, every day three times, each 10 balls, warm water delivery service.Take 6 days, its above-mentioned symptom obviously alleviates.Take two weeks, all cards calm down, and ultrasonic examination gallbladder contraction function is normal.Follow up a case by regular visits to and do not recur.
embodiment 3damp and hotly accumulate malicious type cholecystitis removing toxic substances medicament, the primary raw material medicine getting following weight parts is prepared from (every part for 40g): Herba Salviae Chinensis 12 parts, Semen Cuscutae 20 parts, Herba Sedi 11 parts, the Radix Astragali 28 parts, Fructus Lycii 13 parts, Rhizoma Curcumae 8 parts, Maifanitum 12 parts, Herba Dendrobii 10 parts, Polyporus 9 parts, Fructus Aurantii 11 parts, Fructus Gardeniae 13 parts, 11 parts, Radix Glycyrrhizae, Radix Isatidis 16 parts, Auricled Hedyotis Herb 9 parts, Aralia decaisneana Hance 8 parts, Fructus Toosendan 10 parts.
Above-mentioned damp and hot preparation method of accumulateing malicious type cholecystitis removing toxic substances medicament granule is:
(1) Fructus Gardeniae is pulverized, be laid on the pallet in microwave oven, power 1KW, heat 7 minutes, once stirred every one minute, take out, cool, be ground into fine powder, cross No. six sieves;
(2) first pot is burnt heat, be evenly sprinkled into Testa Tritici, with moderate heat heating, treat that cigarette plays input Fructus Toosendan, every 100kg Fructus Toosendan Testa Tritici 10kg, constantly stirs, and fries 20 minutes, takes out, and sieve removes Testa Tritici, cools, is ground into fine powder, crosses No. six sieves;
(3) all the other the 14 taste medical materials except Fructus Gardeniae and Fructus Toosendan are ground into fine powder respectively, cross No. six sieves;
(4) step (1), step (2) and step (3) gained fine powder and supplementary product starch are put in container and fully mix, add water and make soft material;
(5) step (4) gained soft material is passed through 24 eye mesh screens with fashion of extrusion, make uniform granule;
(6) step (5) gained granule is dry at the temperature of 62 DEG C, the water content control of granule, within 2%, to obtain final product.
model case two:xXX, female, 42 years old.First visit: patient coerces down and chest and diaphragm pain more than 3 years, and doctor trained in Western medicine is examined as " chronic cholecystitis ".When sending out when this is sick only, when outbreak is heavy, hurt like hell, heating fear of cold, vomits bitter, yellowish complexion bluish lip, inappetence, night difficult peacefully sleeping.Though in many ways cure, the state of an illness still.Feeling the pulse, it is hard to resemble left pass string, right stringy and thready pulse, and tongue fur HUANGBAI(sic) is thick greasy micro-dry.Card accumulates poison for damp and hot.Use the present embodiment gained is damp and hot accumulates malicious type cholecystitis removing toxic substances medicament granule, and every day three times, each 15g, boiled water is taken after mixing it with water.Take 5 days, pain comparatively subtracts, and vomiting stops.Yellowish fur gradually moves back, still bitter in mouth.Arteries and veins left pass string is hard softer, right existing thin and delicate.Slightly can take food.Stool every other day a line, still freely not well, oliguria with yellow urine.Crouch night and do not pacify.Take 10 days, fullness and distention in the chest and hypochondrium pain day by day alleviates, and breathes happy, and the vomiting heart is general only complete, and micro-hardship in mouth, can enter diet.Stool day a line, clear urine in large amounts.The left string of pulse condition is gradually put down, and the right side is still thin and delicate, and light red tongue is yellow and moisten.Continue to take one week, pain is stopped entirely, normal sensation in the mouth, and food increases dormancy and adds, and two is just normal, and all diseases disappear.Cholecystitis does not recur so far.
embodiment 4damp and hotly accumulate malicious type cholecystitis removing toxic substances medicament, the primary raw material medicine getting following weight parts is prepared from (every part for 40g): Herba Salviae Chinensis 14 parts, Semen Cuscutae 24 parts, Herba Sedi 15 parts, the Radix Astragali 31 parts, Fructus Lycii 16 parts, Rhizoma Curcumae 10 parts, Maifanitum 14 parts, Herba Dendrobii 14 parts, Polyporus 12 parts, Fructus Aurantii 13 parts, Fructus Gardeniae 15 parts, 13 parts, Radix Glycyrrhizae, Radix Isatidis 20 parts, Auricled Hedyotis Herb 11 parts, Aralia decaisneana Hance 12 parts, Fructus Toosendan 13 parts.
Above-mentioned damp and hot preparation method of accumulateing malicious type cholecystitis removing toxic substances medicament powder is:
(1) Fructus Gardeniae is pulverized, be laid on the pallet in microwave oven, power 1KW, heat 7 minutes, once stirred every one minute, take out, cool, be ground into fine powder, cross No. seven sieves;
(2) first pot is burnt heat, be evenly sprinkled into Testa Tritici, with moderate heat heating, treat that cigarette plays input Fructus Toosendan, every 100kg Fructus Toosendan Testa Tritici 10kg, constantly stirs, and fries 20 minutes, takes out, and sieve removes Testa Tritici, cools, is ground into fine powder, crosses No. seven sieves;
(3) all the other the 14 taste medical materials except Fructus Gardeniae and Fructus Toosendan are ground into fine powder respectively, cross No. seven sieves;
(4) step (1), step (2) and step (3) gained fine powder fully being mixed, by often wrapping 3 grams of subpackages, obtaining final product.
model case three:xXX, man, 50 years old.Paroxysmal has epigastrium pain, and the shoulder back of the body diffuses more than 3 years to the right.Once repeatedly used western medicine, violated during fashion, recurrent exerbation, often brought out after eating fat.The pain increased recently unbearably, and disease opinion has epigastrium pain, can take on back of the body radiation to the right, fever of the body, heavy sensation of the body, restlessness and thirst, indigestion and loss of appetite loss of appetite, the micro-Huang of skin, oliguria with reddish urine, red tongue with yellow fur, stringy and rolling pulse and counting.B ultrasonic shows: gallbladder wall owes smooth, prompting cholecystitis.Card accumulates poison for damp and hot.Use the present embodiment gained is damp and hot accumulates malicious type cholecystitis removing toxic substances medicament powder, every day twice, and each 1 bag, boiled water is taken after mixing it with water.After taking 10 days, above-mentioned symptom obviously alleviates.Continue to take one week, all diseases are all removed, and check B ultrasonic is normal.Recurrence of following up a case by regular visits to that so far there are no.
embodiment 5damp and hotly accumulate malicious type cholecystitis removing toxic substances medicament, the primary raw material medicine getting following weight parts is prepared from (every part for 40g): Herba Salviae Chinensis 13 parts, Semen Cuscutae 22 parts, Herba Sedi 13 parts, the Radix Astragali 30 parts, Fructus Lycii 14 parts, Rhizoma Curcumae 9 parts, Maifanitum 13 parts, Herba Dendrobii 12 parts, Polyporus 11 parts, Fructus Aurantii 12 parts, Fructus Gardeniae 14 parts, 12 parts, Radix Glycyrrhizae, Radix Isatidis 18 parts, Auricled Hedyotis Herb 10 parts, Aralia decaisneana Hance 9 parts, Fructus Toosendan 11 parts.
Above-mentioned damp and hot preparation method of accumulateing malicious type cholecystitis removing toxic substances medicament decoction is:
(1) Fructus Gardeniae is pulverized, be laid on the pallet in microwave oven, power 1KW, heat 7 minutes, once stirred every one minute, take out, cool, be ground into fine powder, cross No. seven sieves;
(2) first pot is burnt heat, be evenly sprinkled into Testa Tritici, with moderate heat heating, treat that cigarette plays input Fructus Toosendan, every 100kg Fructus Toosendan Testa Tritici 10kg, constantly stirs, and fries 20 minutes, takes out, and sieve removes Testa Tritici, cools, is ground into fine powder, crosses No. seven sieves;
(3) Maifanitum is put into marmite, add water, amount of water is 3.5 times of Maifanitum weight, first boils with intense fire and follow-uply gives slow fire boiling 50 minutes, leach medicinal liquid;
(4) Semen Cuscutae is loaded in gauze bag, put into the above-mentioned marmite filling medicinal residues together with all the other the 12 taste medical materials except Fructus Gardeniae, Fructus Toosendan, Maifanitum, add water, amount of water is 5.0 times of the 13 taste medical material gross weights added, first boil with intense fire and follow-uply give slow fire boiling 35 minutes, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid are merged, add step (1) and step (2) gained fine powder, to obtain final product.
test example 1the damp and hot clinical practice of accumulateing malicious type cholecystitis removing toxic substances medicament (embodiment 5) of gained of the present invention: in November ,-2012 in May, 2009, accumulate malicious type cholecystitis 6 hospitals screening 224 example is damp and hot, wherein male 90 example, women 134 example, oldest 63 years old, minimum 28 years old of age, 44.5 years old mean age, the course of disease 5 months-4 years, average course of disease 2.5 years.Be divided into two groups at random, experimental group and matched group.Experimental group male 45 example, women 67 example, oldest 63 years old, minimum 28 years old of age, 44.5 years old mean age, the course of disease 5 months-4 years, average course of disease 2.5 years.Matched group male 45 example, women 67 example, oldest 63 years old, minimum 28 years old of age, 44.5 years old mean age, the course of disease 5 months-4 years, average course of disease 2.5 years.The difference remarkable (P > 0.05) of two groups of patients in the physical data such as sex, age, the course of disease and the state of an illness, does not have statistical significance, has comparability.Experimental group uses products obtained therefrom of the present invention, using method: oral, every day twice (warm), each 230mL, within 7 days, is a course for the treatment of.Matched group uses the damp and hot medicine (as cholagogic and lithagogue tablet, Yinshanlian granules, ZANGYINCHEN sheet, XIAOYAN LIDAN PIAN etc.) accumulateing malicious type cholecystitis of conventional therapy.Curative effect situation criterion: cure: the clinical symptoms of patient disappears completely, and imaging examination result and laboratory examination results all return to normal range; Take a turn for the better: the clinical symptoms of patient disappears substantially, and imaging examination result and laboratory examination results all improve significantly; Invalid: the clinical symptoms of patient, imaging examination result and laboratory examination results are all without any improvement, even increase the weight of.Total effectively comprising cures and takes a turn for the better.After treating two courses for the treatment of, result is as shown in table 1.
Table 1: gained of the present invention is damp and hot accumulates malicious type cholecystitis removing toxic substances medicament compliance test result
Efficacy analysis: after two groups of cases treat 2 courses for the treatment of, experimental group cures 84 examples, and take a turn for the better 25 examples, total effective rate 97.32%; Matched group cures 38 examples, and take a turn for the better 40 examples, total effective rate 69.64%.The clinical efficacy of experimental group is obviously better than matched group, and significant difference (P < 0.05), has statistical significance.
The present invention with pure Chinese herbal medicine such as Herba Salviae Chinensis, Semen Cuscutae, Herba Sedi and the Radixs Astragali for primary raw material, make damp and hot accumulate malicious type cholecystitis removing toxic substances medicament, safety, has no side effect.Herba Salviae Chinensis blood circulation promoting and blood stasis dispelling in side, clearing away heat-damp and promoting diuresis, mass dissipating and swelling eliminating.Semen Cuscutae nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.Herba Sedi clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Radix Astragali invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Fructus Lycii nourishing kidney, lung moistening, tonifying liver, improving eyesight.Rhizoma Curcumae circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.Maifanitum removing toxic substances and promoting granulation, damp eliminating spleen invigorating.Herba Dendrobii promotes the production of body fluid stomach reinforcing, clearing away heat and nourishing YIN.Polyporus promoting diuresis to eliminate damp pathogen.Fructus Aurantii dispelling the stagnated QI, row expectorant, removing food stagnancy.Fructus Gardeniae pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Radix Isatidis heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving.Auricled Hedyotis Herb heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.Aralia decaisneana Hance expelling wind and removing dampness, promoting blood circulation to restore menstrual flow, removing toxic substances and promoting subsidence of swelling.Fructus Toosendan removes damp and hot, clearing away liver-fire, pain relieving, parasite killing.All medicines share, and have the effects such as heat-clearing and toxic substances removing, damp eliminating spleen invigorating, nourishing the liver and kidney, pathogenic fire purging relieving restlessness, promoting flow of QI and blood, mass dissipating and swelling eliminating, removing food stagnancy pain relieving, and for treatment, damp and hot to accumulate malicious type cholecystitis evident in efficacy.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. damp and hot accumulate malicious type cholecystitis removing toxic substances medicament, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Herba Salviae Chinensis 9-16, Semen Cuscutae 15-30, Herba Sedi 9-16, Radix Astragali 20-40, Fructus Lycii 10-20, Rhizoma Curcumae 6-12, Maifanitum 8-16, Herba Dendrobii 8-16, Polyporus 7-14, Fructus Aurantii 9-15, Fructus Gardeniae 12-16, Radix Glycyrrhizae 9-15, Radix Isatidis 12-24, Auricled Hedyotis Herb 8-12, Aralia decaisneana Hance 6-15, Fructus Toosendan 8-16.
2. as claimed in claim 1 damp and hot accumulate malicious type cholecystitis removing toxic substances medicament, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Herba Salviae Chinensis 12-14, Semen Cuscutae 20-24, Herba Sedi 11-15, Radix Astragali 28-31, Fructus Lycii 13-16, Rhizoma Curcumae 8-10, Maifanitum 12-14, Herba Dendrobii 10-14, Polyporus 9-12, Fructus Aurantii 11-13, Fructus Gardeniae 13-15, Radix Glycyrrhizae 11-13, Radix Isatidis 16-20, Auricled Hedyotis Herb 9-11, Aralia decaisneana Hance 8-12, Fructus Toosendan 10-13.
3. as claimed in claim 1 damp and hot accumulate malicious type cholecystitis removing toxic substances medicament, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Herba Salviae Chinensis 13, Semen Cuscutae 22, Herba Sedi 13, the Radix Astragali 30, Fructus Lycii 14, Rhizoma Curcumae 9, Maifanitum 13, Herba Dendrobii 12, Polyporus 11, Fructus Aurantii 12, Fructus Gardeniae 14, Radix Glycyrrhizae 12, Radix Isatidis 18, Auricled Hedyotis Herb 10, Aralia decaisneana Hance 9, Fructus Toosendan 11.
4. damp and hot as described in as arbitrary in claims 1 to 3 accumulates malicious type cholecystitis removing toxic substances medicament, and it is characterized in that, this damp and hot malicious type cholecystitis removing toxic substances medicament that accumulates is made pharmaceutically acceptable pill, and the preparation method of described pill is:
(1) Fructus Gardeniae is pulverized, be laid on the pallet in microwave oven, power 1KW, heat 4-9 minute (preferably heating 7 minutes), once stirred every one minute, take out, cool, be ground into fine powder, cross No. six sieves;
(2) first pot is burnt heat, evenly be sprinkled into Testa Tritici, with moderate heat heating, treat that cigarette plays input Fructus Toosendan, every 100kg Fructus Toosendan Testa Tritici 8-14kg(is every 100kg Fructus Toosendan Testa Tritici 10kg preferably), constantly stir, fry 14-26 minute (preferably frying 20 minutes), take out, sieve removes Testa Tritici, cool, be ground into fine powder, cross No. six sieves;
(3) all the other the 14 taste medical materials except Fructus Gardeniae and Fructus Toosendan are ground into fine powder respectively, cross No. six sieves;
(4) step (1), step (2) and step (3) gained fine powder are fully mixed, add water pill, the weight of obtained every ball is the weight of the preferably obtained every ball of 0.25-0.6g(is 0.4g), dry at the temperature of 50-60 DEG C (preferably dry at the temperature of 55 DEG C), make pill water content control within 8%, to obtain final product.
5. damp and hot as described in as arbitrary in claims 1 to 3 accumulates malicious type cholecystitis removing toxic substances medicament, and it is characterized in that, this damp and hot malicious type cholecystitis removing toxic substances medicament that accumulates is made pharmaceutically acceptable decoction, and the preparation method of described decoction is:
(1) Fructus Gardeniae is pulverized, be laid on the pallet in microwave oven, power 1KW, heat 4-9 minute (preferably heating 7 minutes), once stirred every one minute, take out, cool, be ground into fine powder, cross No. seven sieves;
(2) first pot is burnt heat, evenly be sprinkled into Testa Tritici, with moderate heat heating, treat that cigarette plays input Fructus Toosendan, every 100kg Fructus Toosendan Testa Tritici 8-14kg(is every 100kg Fructus Toosendan Testa Tritici 10kg preferably), constantly stir, fry 14-26 minute (preferably frying 20 minutes), take out, sieve removes Testa Tritici, cool, be ground into fine powder, cross No. seven sieves;
(3) Maifanitum is put into marmite, add water, amount of water be the 2.7-4.2 of Maifanitum weight doubly (preferred amount of water is 3.5 times of Maifanitum weight), first boil follow-up giving slow fire boiling 40-60 minute (preferably first boil with intense fire and follow-uply give slow fire boiling 50 minutes) with intense fire, leach medicinal liquid;
(4) Semen Cuscutae is loaded in gauze bag, the above-mentioned marmite filling medicinal residues is put into together with all the other the 12 taste medical materials except Fructus Gardeniae, Fructus Toosendan, Maifanitum, add water, amount of water is 3.8-6.2 times (preferred amount of water is 5.0 times of the 13 taste medical material gross weights added) of the 13 taste medical material gross weights added, first boil follow-up giving slow fire boiling 30-45 minute (preferably first boil with intense fire and follow-uply give slow fire boiling 35 minutes) with intense fire, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid are merged, add step (1) and step (2) gained fine powder, to obtain final product.
6. damp and hot as described in as arbitrary in claims 1 to 3 accumulates malicious type cholecystitis removing toxic substances medicament, and it is characterized in that, this damp and hot malicious type cholecystitis removing toxic substances medicament that accumulates is made pharmaceutically acceptable granule, and the preparation method of described granule is:
(1) Fructus Gardeniae is pulverized, be laid on the pallet in microwave oven, power 1KW, heat 4-9 minute (preferably heating 7 minutes), once stirred every one minute, take out, cool, be ground into fine powder, cross No. six sieves;
(2) first pot is burnt heat, evenly be sprinkled into Testa Tritici, with moderate heat heating, treat that cigarette plays input Fructus Toosendan, every 100kg Fructus Toosendan Testa Tritici 8-14kg(is every 100kg Fructus Toosendan Testa Tritici 10kg preferably), constantly stir, fry 14-26 minute (preferably frying 20 minutes), take out, sieve removes Testa Tritici, cool, be ground into fine powder, cross No. six sieves;
(3) all the other the 14 taste medical materials except Fructus Gardeniae and Fructus Toosendan are ground into fine powder respectively, cross No. six sieves;
(4) step (1), step (2) and step (3) gained fine powder and supplementary product starch are put in container and fully mix, add water and make soft material;
(5) step (4) gained soft material is passed through 18-28 eye mesh screen (preferably step (4) gained soft material being passed through 24 eye mesh screens with fashion of extrusion) with fashion of extrusion, make uniform granule;
(6) by dry at the temperature of 58 DEG C-68 DEG C for step (5) gained granule (preferably that step (5) gained granule is dry at the temperature of 62 DEG C), the water content control of granule, within 2%, to obtain final product.
7. damp and hot as described in as arbitrary in claims 1 to 3 accumulates malicious type cholecystitis removing toxic substances medicament, and it is characterized in that, this damp and hot malicious type cholecystitis removing toxic substances medicament that accumulates is made pharmaceutically acceptable powder, and the preparation method of described powder is:
(1) pulverized by Fructus Gardeniae, be laid on the pallet in microwave oven, power 1KW, heating 4-9 minute, once stirred every one minute, took out, cooled, be ground into fine powder, crossed No. seven sieves;
(2) first pot is burnt heat, be evenly sprinkled into Testa Tritici, with moderate heat heating, treat that cigarette plays input Fructus Toosendan, every 100kg Fructus Toosendan Testa Tritici 8-14kg, constantly stirs, and fries 14-26 minute, takes out, and sieve removes Testa Tritici, cools, is ground into fine powder, crosses No. seven sieves;
(3) all the other the 14 taste medical materials except Fructus Gardeniae and Fructus Toosendan are ground into fine powder respectively, cross No. seven sieves;
(4) step (1), step (2) and step (3) gained fine powder fully being mixed, by often wrapping 3 grams of subpackages, obtaining final product.
8. damp and hot preparation method of accumulateing malicious type cholecystitis removing toxic substances medicament granule as claimed in claim 7, is characterized in that, heating 7 minutes in step (1).
9. damp and hot preparation method of accumulateing malicious type cholecystitis removing toxic substances medicament granule as claimed in claim 7, is characterized in that, every 100kg Fructus Toosendan Testa Tritici 10kg in step (2).
10. damp and hot preparation method of accumulateing malicious type cholecystitis removing toxic substances medicament granule as claimed in claim 7, is characterized in that, fry 20 minutes in step (2).
CN201510013671.6A 2015-01-12 2015-01-12 Detoxifying preparation for treating damp-heat toxin accumulated type cholecystitis and preparation method of detoxifying preparation Pending CN104491753A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106237232A (en) * 2016-09-26 2016-12-21 防城港思创信息技术有限公司 A kind of clearing heat in YING system purging FU-organs removing toxic substances medicament

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘汉阁: ""中医药治疗胆囊炎浅识"", 《实用中医内科杂志》 *
罗杰: "《补益中药食养一本通》", 31 December 2013, 陕西科学技术出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106237232A (en) * 2016-09-26 2016-12-21 防城港思创信息技术有限公司 A kind of clearing heat in YING system purging FU-organs removing toxic substances medicament

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